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bruno lefebvre

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MUC1 Drives the Progression and Chemoresistance of Clear Cell Renal Carcinomas

Emma Bourdon , Thomas Swierczewski , Marine Goujon , Nihad Boukrout , Sandy Fellah
Cancers, 2024, 16 (2), pp.391. ⟨10.3390/cancers16020391⟩
Article dans une revue inserm-04479812v1
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Cancer Cells Upregulate Tau to Gain Resistance to DNA Damaging Agents

Thomas Rico , Marine Denecha , Raphaelle Caillierez , Thomas Comptdaer , Eric Adriaenssens
Cancers, 2023, 15 (1), pp.116. ⟨10.3390/cancers15010116⟩
Article dans une revue inserm-03985380v1
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Tau promotes oxidative stress-associated cycling neurons in S phase as a pro-survival mechanism: Possible implication for Alzheimer’s disease

Marine Denechaud , Sarah Geurs , Thomas Comptdaer , Séverine Bégard , Alejandro Garcia-Núñez
Progress in Neurobiology, 2023, 223, pp.102386. ⟨10.1016/j.pneurobio.2022.102386⟩
Article dans une revue hal-04309994v1
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Tau Stabilizes Chromatin Compaction

Thomas Rico , Melissa Gilles , Alban Chauderlier , Thomas Comptdaer , Romain Magnez
Frontiers in Cell and Developmental Biology, 2021, 9, pp.740550. ⟨10.3389/fcell.2021.740550⟩
Article dans une revue hal-03429442v1
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Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy

Jin Zheng , Mansour Akbari , Claire Schirmer , Marie-Line Reynaert , Anne Loyens
Acta Neuropathologica Communications, 2020, 8 (1), pp.25. ⟨10.1186/s40478-020-00896-8⟩
Article dans une revue inserm-02999922v1

Genome-wide identification of genic and intergenic neuronal DNA regions bound by Tau protein under physiological and stress conditions

Houda Benhelli-Mokrani , Zeyni Mansuroglu , Alban Chauderlier , Benoit Albaud , David Gentien
Nucleic Acids Research, 2018, ⟨10.1093/nar/gky929⟩
Article dans une revue hal-02404215v1

Tau/DDX6 interaction increases microRNA activity

Alban Chauderlier , Melissa Gilles , Andrea Spolcova , Raphaëlle Caillierez , Maggy Chwastyniak
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2018, 1861 (8), pp.762-772. ⟨10.1016/j.bbagrm.2018.06.006⟩
Article dans une revue hal-02251328v1
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Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin

Zeyni Mansuroglu , Houda Benhelli-Mokrani , Vasco Marcato , Audrey Sultan , Marie Violet
Scientific Reports, 2016, 6 (1), pp.33047. ⟨10.1038/srep33047⟩
Article dans une revue hal-03093346v1

Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo

Marie Violet , Alban Chauderlier , Lucie Delattre , Meryem Tardivel , Meliza Sendid Chouala
Neurobiology of Disease, 2015, 82, pp.540-551. ⟨10.1016/j.nbd.2015.09.003⟩
Article dans une revue hal-03093353v1

Regulation of human MAPT gene expression

Marie-Laure Caillet-Boudin , Luc Buée , Nicolas Sergeant , Bruno Lefebvre
Molecular Neurodegeneration, 2015, 10 (1), pp.28. ⟨10.1186/s13024-015-0025-8⟩
Article dans une revue inserm-04532389v1
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A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions

Marie Violet , Lucie Delattre , Meryem Tardivel , Audrey Sultan , Alban Chauderlier
Frontiers in Cellular Neuroscience, 2014, 8 (2), pp.350-358. ⟨10.3389/fncel.2014.00084⟩
Article dans une revue inserm-04532387v1

mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells

Olivier Le Bacquer , Gurvan Queniat , Valery Gmyr , Julie Kerr-Conte , Bruno Lefebvre
Journal of Endocrinology, 2013, 216 (1), pp.21-29. ⟨10.1530/JOE-12-0351⟩
Article dans une revue inserm-04532381v1

Regulation and functional effects of ZNT8 in human pancreatic islets

Bruno Lefebvre , Brigitte Vandewalle , Anne-Sophie Balavoine , Gurvan Queniat , Ericka Moerman
Journal of Endocrinology, 2012, 214 (2), pp.225-232. ⟨10.1530/JOE-12-0071⟩
Article dans une revue inserm-04532375v1

The proteosomal degradation of retinoid X receptora reprograms Peroxisone Proliferator-Activated-Receptor g transcriptional activity in obesity

B. Lefebvre , Y. Yacir Benomar , A. Guedin , A. Langlois , Nathalie Hennuyer
Journal of Clinical Investigation, 2010, 120, pp.1454-1468
Article dans une revue hal-02661661v1

Efficient gene delivery and silencing of mouse and human pancreatic islets

Bruno Lefebvre , Brigitte Vandewalle , Justine Longue , Ericka Moerman , Bruno Lukowiak
BMC Biotechnology, 2010, 10 (1), pp.28. ⟨10.1186/1472-6750-10-28⟩
Article dans une revue inserm-04532371v1

5′-AZA induces Ngn3 expression and endocrine differentiation in the PANC-1 human ductal cell line

Bruno Lefebvre , Sandrine Belaich , Justine Longue , Brigitte Vandewalle , Jose Oberholzer
Biochemical and Biophysical Research Communications, 2010, 391 (1), pp.305-309. ⟨10.1016/j.bbrc.2009.11.054⟩
Article dans une revue inserm-04532368v1

Coadministration of coenzyme Q prevents rosiglitazone-induced adipogenesis in ob/ob mice

Maria Carmen Carmona , Philippe Lefebvre , Bruno Lefebvre , Anne Galinier , Alexandre Benani
International Journal of Obesity, 2009, 33 (2), pp.204-11. ⟨10.1038/ijo.2008.265⟩
Article dans une revue hal-00462260v1

Induction of CXCR2 Receptor by Peroxisome Proliferator-Activated Receptor γ in Human Macrophages

Elena Rigamonti , Coralie Fontaine , Bruno Lefebvre , Christian Duhem , Philippe Lefebvre
Arteriosclerosis, Thrombosis, and Vascular Biology, 2008, 28 (5), pp.932-939. ⟨10.1161/ATVBAHA.107.161679⟩
Article dans une revue inserm-04532363v1

PPARγ-dependent and -independent effects of Rosiglitazone on lipotoxic human pancreatic islets

Brigitte Vandewalle , Ericka Moerman , Bruno Lefebvre , Frédérique Defrance , Valéry Gmyr
Biochemical and Biophysical Research Communications, 2008, 366 (4), pp.1096-1101. ⟨10.1016/j.bbrc.2007.12.088⟩
Article dans une revue inserm-04532358v1
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The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor

Sébastien Flajollet , Bruno Lefebvre , Céline Cudejko , Bart Staels , Philippe Lefebvre
Molecular and Cellular Endocrinology, 2007, 270 (1-2), pp.23. ⟨10.1016/j.mce.2007.02.004⟩
Article dans une revue hal-00531916v1

Down-regulation of the tumor suppressor gene RAR{beta}2 through the PI3K/Akt signaling pathway.

Bruno Lefebvre , Céline Brand , Sébastien Flajollet , Philippe Lefebvre
Mol Endocrinol, 2006, 20 (9), pp.2109-21. ⟨10.1210/me.2005-0321⟩
Article dans une revue inserm-00079317v1

Distinct roles of the steroid receptor coactivator 1 and of MED1 in retinoid-induced transcription and cellular differentiation.

Sébastien Flajollet , Bruno Lefebvre , Christophe Rachez , Philippe Lefebvre
Journal of Biological Chemistry, 2006, 281, pp.20338-48. ⟨10.1074/jbc.M603023200⟩
Article dans une revue inserm-00079314v1

Regulation of Human ApoA-I by Gemfibrozil and Fenofibrate Through Selective Peroxisome Proliferator-Activated Receptor α Modulation

Hélène Duez , Bruno Lefebvre , Philippe Poulain , Inés Pineda Torra , Frédéric Percevault
Arteriosclerosis, Thrombosis, and Vascular Biology, 2005, 25 (3), pp.585-591. ⟨10.1161/01.ATV.0000154140.73570.00⟩
Article dans une revue inserm-04532346v1

Transcriptional activities of retinoic acid receptors

P. Lefebvre , P.J. Martin , S. Flajollet , S. Dedieu , X. Billaut
Vitam. Horm., 2005, 70, pp.199-264
Article dans une revue hal-00013311v1

Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma.

Christel Rousseaux , Bruno Lefebvre , Laurent Dubuquoy , Philippe Lefebvre , Olivier Romano
Journal of Experimental Medicine, 2005, 201 (8), pp.1205-15. ⟨10.1084/jem.20041948⟩
Article dans une revue hal-00187736v1

Phosphorylation of histone H3 is functionally linked to retinoic acid receptor β promoter activation

Bruno Lefebvre , Keiko Ozato , Philippe Lefebvre
EMBO Reports, 2002, 3 (4), pp.335-340. ⟨10.1093/embo-reports/kvf066⟩
Article dans une revue inserm-04532312v1

H11-H12 Loop Retinoic Acid Receptor Mutants Exhibit Distinct trans-Activating and trans-Repressing Activities in the Presence of Natural or Synthetic Retinoids

Bruno Lefebvre , Arnaud Mouchon , Pierre Formstecher , Philippe Lefebvre
Biochemistry, 1998, 37 (26), pp.9240-9249. ⟨10.1021/bi9804840⟩
Article dans une revue inserm-04532229v1

Binding of Retinoic Acid Receptor Heterodimers to DNA

Philippe Lefebvre , Arnaud Mouchon , Bruno Lefebvre , Pierre Formstecher
Journal of Biological Chemistry, 1998, 273 (20), pp.12288-12295. ⟨10.1074/jbc.273.20.12288⟩
Article dans une revue inserm-04532228v1

Distinct modes of interaction of the retinoic acid receptor alpha with natural and synthetic retinoids

Bruno Lefebvre , Arnaud Mouchon , Pierre Formstecher , Philippe Lefebvre
Molecular and Cellular Endocrinology, 1998, 139 (1-2), pp.161-169. ⟨10.1016/s0303-7207(98)00065-3⟩
Article dans une revue inserm-04532233v1