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Michel Cogné

44
Documents

Présentation

Domaines de recherche


Compétences

Immunologie Génétique

Publications

"Animals"

Impaired Lysosomal Function Underlies Monoclonal Light Chain–Associated Renal Fanconi Syndrome

Alessandro Luciani , Christophe Sirac , Sara Terryn , Vincent Javaugue , Jenny Ann Prange
Journal of the American Society of Nephrology, 2016, 27 (7), pp.2049-2061. ⟨10.1681/ASN.2015050581⟩
Article dans une revue hal-02364437v1

Immunoglobulin genes undergo legitimate repair in human B cells not only after cis- but also frequent trans-class switch recombination.

Brice Laffleur , Sylvia M. Bardet , Armand Garot , M Brousse , A Baylet
Genes and Immunity, 2014, 15 (5), pp.341-6. ⟨10.1038/gene.2014.25⟩
Article dans une revue hal-01112042v1

The Eμ enhancer region influences H chain expression and B cell fate without impacting IgVH repertoire and immune response in vivo.

Marie Marquet , Armand Garot , Sébastien Bender , Claire Carrion , Pauline Rouaud
Journal of Immunology, 2014, 193 (3), pp.1171-83. ⟨10.4049/jimmunol.1302868⟩
Article dans une revue hal-01110453v1

The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells.

Pauline Rouaud , Christelle Vincent-Fabert , Alexis Saintamand , Rémi Fiancette , Marie Marquet
Journal of Experimental Medicine, 2013, 210 (8), pp.1501-7. ⟨10.1084/jem.20130072⟩
Article dans une revue hal-00903790v1

Production of human or humanized antibodies in mice.

Brice Laffleur , Virginie Pascal , Christophe Sirac , Michel Cogné
Methods in Molecular Biology, 2012, 901, pp.149-59. ⟨10.1007/978-1-61779-931-0_9⟩
Article dans une revue hal-00779395v1

[IgH locus suicide recombination, or when B cells surrender!].

Sophie Péron , Brice Laffleur , Nicolas Denis-Lagache , Jeanne Cook-Moreau , Matthieu Filloux
Médecine/Sciences, 2012, 28 (5), pp.551-4. ⟨10.1051/medsci/2012285023⟩
Article dans une revue hal-00779352v1

Enhancers located in heavy chain regulatory region (hs3a, hs1,2, hs3b, and hs4) are dispensable for diversity of VDJ recombination.

Pauline Rouaud , Christelle Vincent-Fabert , Rémi Fiancette , Michel Cogné , Eric Pinaud
Journal of Biological Chemistry, 2012, 287 (11), pp.8356-60. ⟨10.1074/jbc.M112.341024⟩
Article dans une revue hal-00696502v1
Image document

Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.

Laureline Berthelot , Christina Papista , Thiago T Maciel , Martine Biarnes-Pelicot , Emilie Tissandie
Journal of Experimental Medicine, 2012, 209 (4), pp.793-806. ⟨10.1084/jem.20112005⟩
Article dans une revue hal-00903832v1

Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin.

Pauline Rouaud , Rémi Fiancette , Christelle Vincent-Fabert , Virginie Magnone , Michel Cogné
Oncotarget, 2012, 3 (5), pp.586-93
Article dans une revue hal-00779350v1

Class-specific effector functions of therapeutic antibodies.

Virginie Pascal , Brice Laffleur , Michel Cogné
Methods in Molecular Biology, 2012, 901, pp.295-317. ⟨10.1007/978-1-61779-931-0_19⟩
Article dans une revue hal-00779398v1

Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development.

Aurélien Tinguely , Guillaume Chemin , Sophie Péron , Christophe Sirac , Stéphane Reynaud
Molecular and Cellular Biology, 2012, 32 (1), pp.107-17. ⟨10.1128/MCB.06138-11⟩
Article dans une revue hal-00696497v1

Toward understanding renal Fanconi syndrome: step by step advances through experimental models.

Christophe Sirac , Franck Bridoux , Marie Essig , Olivier Devuyst , Guy Touchard
Contributions to Nephrology, 2011, 169, pp.247-61. ⟨10.1159/000313962⟩
Article dans une revue hal-00696465v1

Similarity of fine specificity of IgA anti-gliadin antibodies between patients with celiac disease and humanized α1KI mice.

Daniel Sánchez , Gaël Champier , Armelle Cuvillier , Michel Cogné , Aneta Pekáriková
Journal of Agricultural and Food Chemistry, 2011, 59 (7), pp.3092-100. ⟨10.1021/jf1044519⟩
Article dans une revue hal-00696473v1

The IgH locus 3' regulatory region: pulling the strings from behind.

Eric Pinaud , Marie Marquet , Rémi Fiancette , Sophie Péron , Christelle Vincent-Fabert
Advances in immunology, 2011, 110, pp.27-70. ⟨10.1016/B978-0-12-387663-8.00002-8⟩
Article dans une revue hal-00696444v1

Strategies to model AL amyloidosis in mice.

Christophe Sirac , Sébastien Bender , Arnaud Jaccard , Franck Bridoux , C. Lacombe
Amyloid: The Journal of Protein Folding Disorders, 2011, 18 (Suppl 1), pp.45-47. ⟨10.3109/13506129.2011.574354016⟩
Article dans une revue hal-00617188v2

Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia.

Séverine Coulon , Michaël Dussiot , Damien Grapton , Thiago Trovati Maciel , Pamella Huey Mei Wang
Nature Medicine, 2011, 17 (11), pp.1456-65. ⟨10.1038/nm.2462⟩
Article dans une revue hal-00696490v1

A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene.

Rémi Fiancette , Pauline Rouaud , Christelle Vincent-Fabert , Brice Laffleur , Virginie Magnone
Journal of Immunology, 2011, 187 (11), pp.5772-82. ⟨10.4049/jimmunol.1102059⟩
Article dans une revue hal-00696493v1

Multiple RNA surveillance mechanisms cooperate to reduce the amount of nonfunctional Ig kappa transcripts.

Guillaume Chemin , Aurélien Tinguely , Christophe Sirac , Fabien Lechouane , Sophie Duchez
Journal of Immunology, 2010, 184 (9), pp.5009-17. ⟨10.4049/jimmunol.0902949⟩
Article dans une revue hal-00511941v1

A myeloma translocation-like model associating CCND1 with the immunoglobulin heavy-chain locus 3' enhancers does not promote by itself B-cell malignancies.

Rémi Fiancette , Rada Amin , Véronique Truffinet , Christelle Vincent-Fabert , Nadine Cogné
Leukemia Research, 2010, 34 (8), pp.1043-51. ⟨10.1016/j.leukres.2009.11.017⟩
Article dans une revue hal-00514237v1

In vivo redundant function of the 3' IgH regulatory element HS3b in the mouse.

Anne-Gaëlle Bébin , Claire Carrion , Marie Marquet , Nadine Cogné , Sandrine Lecardeur
Journal of Immunology, 2010, 184 (7), pp.3710-7. ⟨10.4049/jimmunol.0901978⟩
Article dans une revue hal-00514232v1

Ig synthesis and class switching do not require the presence of the hs4 enhancer in the 3' IgH regulatory region.

Christelle Vincent-Fabert , Véronique Truffinet , Rémi Fiancette , Nadine Cogné , Michel Cogné
Journal of Immunology, 2009, 182 (11), pp.6926-32. ⟨10.4049/jimmunol.0900214⟩
Article dans une revue hal-00443742v1

Genetic background modulates susceptibility to oncogen-driven proliferation and lymphoma occurrence in mice carrying a deregulated c-myc transgene.

Christelle Vincent-Fabert , Rémi Fiancette , Véronique Truffinet , Nadine Cogné , Michel Cogné
Leukemia Research, 2009, 33 (11), pp.e203-6. ⟨10.1016/j.leukres.2009.05.018⟩
Article dans une revue hal-00514240v1

[Physiopathology of herpetiform dermatitis. Current data]

V. Doffoel-Hantz , Michel Cogné , Agnès Sparsa , J.-M. Bonnetblanc , Mireille Drouet
Annales de Dermatologie et de Vénéréologie, 2008, 135 (11), pp.784-8; quiz 783. ⟨10.1016/j.annder.2008.02.030⟩
Article dans une revue hal-00363969v1

S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase.

Robert Wuerffel , Lili Wang , Fernando Grigera , John Manis , Erik Selsing
Immunity, 2007, 27 (5), pp.711-22. ⟨10.1016/j.immuni.2007.09.007⟩
Article dans une revue hal-00363968v1

The 3' IgH locus control region is sufficient to deregulate a c-myc transgene and promote mature B cell malignancies with a predominant Burkitt-like phenotype.

Véronique Truffinet , Eric Pinaud , Nadine Cogné , Barbara Petit , Laurence Guglielmi
Journal of Immunology, 2007, 179 (9), pp.6033-6042
Article dans une revue hal-00181178v1

Use of both CD63 up regulation and IgE down regulation for the flow cytometric analysis of allergen induced basophil activation. Definition of an activation index.

Jean Sainte-Laudy , Ahmed Boumédiène , F. Touraine , Isabelle Orsel , C. Brianchon
Inflammation Research, 2007, 56 (7), pp.291-6. ⟨10.1007/s00011-007-7014-5⟩
Article dans une revue hal-00166018v1

Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity.

Christophe Sirac , Claire Carrion , Sophie Duchez , Isabelle Comte , Michel Cogné
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (20), pp.7747-52. ⟨10.1073/pnas.0509121103⟩
Article dans une revue hal-00073857v1

Role of the monoclonal kappa chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi syndrome.

Christophe Sirac , Franck Bridoux , Claire Carrion , Olivier Devuyst , Béatrice Fernandez
Blood, 2006, 108 (2), pp.536-543. ⟨10.1182/blood-2005-11-4419⟩
Article dans une revue hal-00085051v1

Germ line transcription in mice bearing neor gene downstream of Igamma3 exon in the Ig heavy chain locus.

Maha Samara , Zéliha Oruc , Hei-Lanne Dougier , Tawer Essawi , Michel Cogné
International Immunology, 2006, 18 (4), pp.581-589. ⟨10.1093/intimm/dxh400⟩
Article dans une revue hal-00021571v1

Interallelic class switch recombination can reverse allelic exclusion and allow trans-complementation of an IgH locus switching defect.

Hei-Lanne Dougier , Stéphane Reynaud , Eric Pinaud , Claire Carrion , Laurent Delpy
European Journal of Immunology, 2006, 36 (8), pp.2181-91. ⟨10.1002/eji.200535529⟩
Article dans une revue hal-00088115v1

Interallelic class switch recombination contributes significantly to class switching in mouse B cells.

Stéphane Reynaud , Laurent Delpy , Laurence Fleury , Hei-Lanne Dougier , Christophe Sirac
Journal of Immunology, 2005, 174 (10), pp.6176-83
Article dans une revue hal-00458866v1

Transcription-dependent somatic hypermutation occurs at similar levels on functional and nonfunctional rearranged IgH alleles.

Laurent Delpy , Christophe Sirac , Caroline Le Morvan , Michel Cogné
Journal of Immunology, 2004, 173 (3), pp.1842-8
Article dans une revue hal-00023372v1

Induction of somatic hypermutation by antigen-specific B cell receptors in the human BL2 cell line.

Florence Glaudet , Vincent Denis , Michel Cogné , Ahmed Amine Khamlichi
European Journal of Immunology, 2004, 34 (6), pp.1637-45. ⟨10.1002/eji.200324741⟩
Article dans une revue hal-00023350v1

Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

Ahmed Amine Khamlichi , Florence Glaudet , Zéliha Oruc , Vincent Denis , Marc Le Bert
Blood, 2004, 103 (10), pp.3828-36. ⟨10.1182/blood-2003-10-3470⟩
Article dans une revue hal-00023269v1

Immunologic basis for the rare occurrence of true nonsecretory plasma cell dyscrasias.

Catherine Decourt , Horia Radu Galea , Christophe Sirac , Michel Cogné
Journal of Leukocyte Biology, 2004, 76 (3), pp.528-36. ⟨10.1189/jlb.0803382⟩
Article dans une revue hal-00023271v1

RNA surveillance down-regulates expression of nonfunctional kappa alleles and detects premature termination within the last kappa exon.

Laurent Delpy , Christophe Sirac , Emmanuelle Magnoux , Sophie Duchez , Michel Cogné
Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (19), pp.7375-80. ⟨10.1073/pnas.0305586101⟩
Article dans une revue hal-00023270v1

Germ-line transcription occurs on both the functional and the non-functional alleles of immunoglobulin constant heavy chain genes.

Laurent Delpy , Marc Le Bert , Michel Cogné , Ahmed Amine Khamlichi
European Journal of Immunology, 2003, 33 (8), pp.2108-13. ⟨10.1002/eji.200323969⟩
Article dans une revue hal-00023385v1

Insulators to improve expression of a 3(')IgH LCR-driven reporter gene in transgenic mouse models.

Laurence Guglielmi , Marc Le Bert , Véronique Truffinet , Michel Cogné , Yves Denizot
Biochemical and Biophysical Research Communications, 2003, 307 (3), pp.466-71. ⟨10.1016/S0006-291X(03)01185-9⟩
Article dans une revue hal-00023524v1

Combination of 3' and 5' IgH regulatory elements mimics the B-specific endogenous expression pattern of IgH genes from pro-B cells to mature B cells in a transgenic mouse model.

Laurence Guglielmi , Marc Le Bert , Isabelle Comte , Marie Laure Dessain , Mireille Drouet
Biochimica et Biophysica Acta - Molecular Cell Research, 2003, 1642 (3), pp.181-90. ⟨10.1016/j.bbamcr.2003.08.005⟩
Article dans une revue hal-00023378v1

The immunoglobulin heavy-chain locus hs3b and hs4 3' enhancers are dispensable for VDJ assembly and somatic hypermutation.

Caroline Le Morvan , Eric Pinaud , Catherine Decourt , Armelle Cuvillier , Michel Cogné
Blood, 2003, 102 (4), pp.1421-7. ⟨10.1182/blood-2002-12-3827⟩
Article dans une revue hal-00023823v1

Light chain myeloma plasma cells induce a strong cell-mediated immune response mainly directed against the monoclonal light chain determinants in a murine experimental model.

Horia Galea , Yves Denizot , Michel Cogné
Cancer Immunology, Immunotherapy, 2002, 51 (4), pp.229-34. ⟨10.1007/s00262-002-0274-6⟩
Article dans une revue hal-00023825v1

GM-CSF and IL-12 production by malignant plasma cells promotes cell-mediated immune responses against monoclonal Ig determinants in a light chain myeloma model.

H.R. Galea , Michel Cogné
Clinical and Experimental Immunology, 2002, 129 (2), pp.247-53. ⟨10.1046/j.1365-2249.2002.01929.x⟩
Article dans une revue hal-00023536v1

B cell development arrest upon insertion of a neo gene between JH and Emu: promoter competition results in transcriptional silencing of germline JH and complete VDJ rearrangements.

Laurent Delpy , Catherine Decourt , Marc Le Bert , Michel Cogné
Journal of Immunology, 2002, 169 (12), pp.6875-82
Article dans une revue hal-00023696v1

Characterization of the murine gene for subunit VIIaL of cytochrome c oxidase.

K. Chantrel-Groussard , Laurent Delpy , Marie-Hélène Ratinaud , Michel Cogné
Comptes rendus de l’Académie des sciences. Série III, Sciences de la vie, 2001, 324 (12), pp.1117-23
Article dans une revue hal-00458870v1