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Michel Cogné

21
Documents

Présentation

Domaines de recherche


Compétences

Immunologie Génétique

Publications

"Immunoglobulin Heavy Chains"

The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells.

Pauline Rouaud , Christelle Vincent-Fabert , Alexis Saintamand , Rémi Fiancette , Marie Marquet
Journal of Experimental Medicine, 2013, 210 (8), pp.1501-7. ⟨10.1084/jem.20130072⟩
Article dans une revue hal-00903790v1

[IgH locus suicide recombination, or when B cells surrender!].

Sophie Péron , Brice Laffleur , Nicolas Denis-Lagache , Jeanne Cook-Moreau , Matthieu Filloux
Médecine/Sciences, 2012, 28 (5), pp.551-4. ⟨10.1051/medsci/2012285023⟩
Article dans une revue hal-00779352v1

Enhancers located in heavy chain regulatory region (hs3a, hs1,2, hs3b, and hs4) are dispensable for diversity of VDJ recombination.

Pauline Rouaud , Christelle Vincent-Fabert , Rémi Fiancette , Michel Cogné , Eric Pinaud
Journal of Biological Chemistry, 2012, 287 (11), pp.8356-60. ⟨10.1074/jbc.M112.341024⟩
Article dans une revue hal-00696502v1

Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development.

Aurélien Tinguely , Guillaume Chemin , Sophie Péron , Christophe Sirac , Stéphane Reynaud
Molecular and Cellular Biology, 2012, 32 (1), pp.107-17. ⟨10.1128/MCB.06138-11⟩
Article dans une revue hal-00696497v1

The IgH locus 3' regulatory region: pulling the strings from behind.

Eric Pinaud , Marie Marquet , Rémi Fiancette , Sophie Péron , Christelle Vincent-Fabert
Advances in immunology, 2011, 110, pp.27-70. ⟨10.1016/B978-0-12-387663-8.00002-8⟩
Article dans une revue hal-00696444v1

A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene.

Rémi Fiancette , Pauline Rouaud , Christelle Vincent-Fabert , Brice Laffleur , Virginie Magnone
Journal of Immunology, 2011, 187 (11), pp.5772-82. ⟨10.4049/jimmunol.1102059⟩
Article dans une revue hal-00696493v1

A myeloma translocation-like model associating CCND1 with the immunoglobulin heavy-chain locus 3' enhancers does not promote by itself B-cell malignancies.

Rémi Fiancette , Rada Amin , Véronique Truffinet , Christelle Vincent-Fabert , Nadine Cogné
Leukemia Research, 2010, 34 (8), pp.1043-51. ⟨10.1016/j.leukres.2009.11.017⟩
Article dans une revue hal-00514237v1

In vivo redundant function of the 3' IgH regulatory element HS3b in the mouse.

Anne-Gaëlle Bébin , Claire Carrion , Marie Marquet , Nadine Cogné , Sandrine Lecardeur
Journal of Immunology, 2010, 184 (7), pp.3710-7. ⟨10.4049/jimmunol.0901978⟩
Article dans une revue hal-00514232v1

Ig synthesis and class switching do not require the presence of the hs4 enhancer in the 3' IgH regulatory region.

Christelle Vincent-Fabert , Véronique Truffinet , Rémi Fiancette , Nadine Cogné , Michel Cogné
Journal of Immunology, 2009, 182 (11), pp.6926-32. ⟨10.4049/jimmunol.0900214⟩
Article dans une revue hal-00443742v1

The 3' IgH locus control region is sufficient to deregulate a c-myc transgene and promote mature B cell malignancies with a predominant Burkitt-like phenotype.

Véronique Truffinet , Eric Pinaud , Nadine Cogné , Barbara Petit , Laurence Guglielmi
Journal of Immunology, 2007, 179 (9), pp.6033-6042
Article dans une revue hal-00181178v1

Interallelic class switch recombination can reverse allelic exclusion and allow trans-complementation of an IgH locus switching defect.

Hei-Lanne Dougier , Stéphane Reynaud , Eric Pinaud , Claire Carrion , Laurent Delpy
European Journal of Immunology, 2006, 36 (8), pp.2181-91. ⟨10.1002/eji.200535529⟩
Article dans une revue hal-00088115v1

The polymorphism of the locus control region lying downstream the human IgH locus is restricted to hs1,2 but not to hs3 and hs4 enhancers.

Laurence Guglielmi , Véronique Truffinet , Emmanuelle Magnoux , Michel Cogné , Yves Denizot
Immunology Letters, 2004, 94 (1-2), pp.77-81. ⟨10.1016/j.imlet.2004.04.003⟩
Article dans une revue hal-00023366v1

Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

Ahmed Amine Khamlichi , Florence Glaudet , Zéliha Oruc , Vincent Denis , Marc Le Bert
Blood, 2004, 103 (10), pp.3828-36. ⟨10.1182/blood-2003-10-3470⟩
Article dans une revue hal-00023269v1

Transcription-dependent somatic hypermutation occurs at similar levels on functional and nonfunctional rearranged IgH alleles.

Laurent Delpy , Christophe Sirac , Caroline Le Morvan , Michel Cogné
Journal of Immunology, 2004, 173 (3), pp.1842-8
Article dans une revue hal-00023372v1

Insulators to improve expression of a 3(')IgH LCR-driven reporter gene in transgenic mouse models.

Laurence Guglielmi , Marc Le Bert , Véronique Truffinet , Michel Cogné , Yves Denizot
Biochemical and Biophysical Research Communications, 2003, 307 (3), pp.466-71. ⟨10.1016/S0006-291X(03)01185-9⟩
Article dans une revue hal-00023524v1

Combination of 3' and 5' IgH regulatory elements mimics the B-specific endogenous expression pattern of IgH genes from pro-B cells to mature B cells in a transgenic mouse model.

Laurence Guglielmi , Marc Le Bert , Isabelle Comte , Marie Laure Dessain , Mireille Drouet
Biochimica et Biophysica Acta - Molecular Cell Research, 2003, 1642 (3), pp.181-90. ⟨10.1016/j.bbamcr.2003.08.005⟩
Article dans une revue hal-00023378v1

Germ-line transcription occurs on both the functional and the non-functional alleles of immunoglobulin constant heavy chain genes.

Laurent Delpy , Marc Le Bert , Michel Cogné , Ahmed Amine Khamlichi
European Journal of Immunology, 2003, 33 (8), pp.2108-13. ⟨10.1002/eji.200323969⟩
Article dans une revue hal-00023385v1

The beta-globin HS4 insulator confers copy-number dependent expression of IgH regulatory elements in stable B cell transfectants.

Laurence Guglielmi , Véronique Truffinet , Michel Cogné , Yves Denizot
Immunology Letters, 2003, 89 (2-3), pp.119-23. ⟨10.1016/S0165-2478(03)00126-3⟩
Article dans une revue hal-00023379v1

The immunoglobulin heavy-chain locus hs3b and hs4 3' enhancers are dispensable for VDJ assembly and somatic hypermutation.

Caroline Le Morvan , Eric Pinaud , Catherine Decourt , Armelle Cuvillier , Michel Cogné
Blood, 2003, 102 (4), pp.1421-7. ⟨10.1182/blood-2002-12-3827⟩
Article dans une revue hal-00023823v1

Molecular study of an IgG1kappa cryoglobulin yielding organized microtubular deposits and glomerulonephritis in the course of chronic lymphocytic leukaemia.

H.R. Galea , Franck Bridoux , Jean-Claude Aldigier , François Paraf , Dominique Bordessoule
Clinical and Experimental Immunology, 2002, 129 (1), pp.113-8. ⟨10.1046/j.1365-2249.2002.01896.x⟩
Article dans une revue hal-00023688v1

B cell development arrest upon insertion of a neo gene between JH and Emu: promoter competition results in transcriptional silencing of germline JH and complete VDJ rearrangements.

Laurent Delpy , Catherine Decourt , Marc Le Bert , Michel Cogné
Journal of Immunology, 2002, 169 (12), pp.6875-82
Article dans une revue hal-00023696v1