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The IgH 3' regulatory region controls somatic hypermutation in germinal center B cells.
Pauline Rouaud
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Christelle Vincent-Fabert
,
Alexis Saintamand
,
Rémi Fiancette
,
Marie Marquet
Article dans une revue
hal-00903790v1
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[IgH locus suicide recombination, or when B cells surrender!].
Sophie Péron
,
Brice Laffleur
,
Nicolas Denis-Lagache
,
Jeanne Cook-Moreau
,
Matthieu Filloux
Article dans une revue
hal-00779352v1
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Enhancers located in heavy chain regulatory region (hs3a, hs1,2, hs3b, and hs4) are dispensable for diversity of VDJ recombination.
Pauline Rouaud
,
Christelle Vincent-Fabert
,
Rémi Fiancette
,
Michel Cogné
,
Eric Pinaud
Article dans une revue
hal-00696502v1
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Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development.
Aurélien Tinguely
,
Guillaume Chemin
,
Sophie Péron
,
Christophe Sirac
,
Stéphane Reynaud
Article dans une revue
hal-00696497v1
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The IgH locus 3' regulatory region: pulling the strings from behind.
Eric Pinaud
,
Marie Marquet
,
Rémi Fiancette
,
Sophie Péron
,
Christelle Vincent-Fabert
Article dans une revue
hal-00696444v1
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A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene.
Rémi Fiancette
,
Pauline Rouaud
,
Christelle Vincent-Fabert
,
Brice Laffleur
,
Virginie Magnone
Article dans une revue
hal-00696493v1
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A myeloma translocation-like model associating CCND1 with the immunoglobulin heavy-chain locus 3' enhancers does not promote by itself B-cell malignancies.
Rémi Fiancette
,
Rada Amin
,
Véronique Truffinet
,
Christelle Vincent-Fabert
,
Nadine Cogné
Article dans une revue
hal-00514237v1
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In vivo redundant function of the 3' IgH regulatory element HS3b in the mouse.
Anne-Gaëlle Bébin
,
Claire Carrion
,
Marie Marquet
,
Nadine Cogné
,
Sandrine Lecardeur
Article dans une revue
hal-00514232v1
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Ig synthesis and class switching do not require the presence of the hs4 enhancer in the 3' IgH regulatory region.
Christelle Vincent-Fabert
,
Véronique Truffinet
,
Rémi Fiancette
,
Nadine Cogné
,
Michel Cogné
Article dans une revue
hal-00443742v1
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The 3' IgH locus control region is sufficient to deregulate a c-myc transgene and promote mature B cell malignancies with a predominant Burkitt-like phenotype.
Véronique Truffinet
,
Eric Pinaud
,
Nadine Cogné
,
Barbara Petit
,
Laurence Guglielmi
Journal of Immunology, 2007, 179 (9), pp.6033-6042
Article dans une revue
hal-00181178v1
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Interallelic class switch recombination can reverse allelic exclusion and allow trans-complementation of an IgH locus switching defect.
Hei-Lanne Dougier
,
Stéphane Reynaud
,
Eric Pinaud
,
Claire Carrion
,
Laurent Delpy
Article dans une revue
hal-00088115v1
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The polymorphism of the locus control region lying downstream the human IgH locus is restricted to hs1,2 but not to hs3 and hs4 enhancers.
Laurence Guglielmi
,
Véronique Truffinet
,
Emmanuelle Magnoux
,
Michel Cogné
,
Yves Denizot
Article dans une revue
hal-00023366v1
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Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.
Ahmed Amine Khamlichi
,
Florence Glaudet
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Zéliha Oruc
,
Vincent Denis
,
Marc Le Bert
Article dans une revue
hal-00023269v1
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Transcription-dependent somatic hypermutation occurs at similar levels on functional and nonfunctional rearranged IgH alleles.
Laurent Delpy
,
Christophe Sirac
,
Caroline Le Morvan
,
Michel Cogné
Journal of Immunology, 2004, 173 (3), pp.1842-8
Article dans une revue
hal-00023372v1
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Insulators to improve expression of a 3(')IgH LCR-driven reporter gene in transgenic mouse models.
Laurence Guglielmi
,
Marc Le Bert
,
Véronique Truffinet
,
Michel Cogné
,
Yves Denizot
Article dans une revue
hal-00023524v1
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Combination of 3' and 5' IgH regulatory elements mimics the B-specific endogenous expression pattern of IgH genes from pro-B cells to mature B cells in a transgenic mouse model.
Laurence Guglielmi
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Marc Le Bert
,
Isabelle Comte
,
Marie Laure Dessain
,
Mireille Drouet
Article dans une revue
hal-00023378v1
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Germ-line transcription occurs on both the functional and the non-functional alleles of immunoglobulin constant heavy chain genes.
Laurent Delpy
,
Marc Le Bert
,
Michel Cogné
,
Ahmed Amine Khamlichi
Article dans une revue
hal-00023385v1
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The beta-globin HS4 insulator confers copy-number dependent expression of IgH regulatory elements in stable B cell transfectants.
Laurence Guglielmi
,
Véronique Truffinet
,
Michel Cogné
,
Yves Denizot
Article dans une revue
hal-00023379v1
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The immunoglobulin heavy-chain locus hs3b and hs4 3' enhancers are dispensable for VDJ assembly and somatic hypermutation.
Caroline Le Morvan
,
Eric Pinaud
,
Catherine Decourt
,
Armelle Cuvillier
,
Michel Cogné
Article dans une revue
hal-00023823v1
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Molecular study of an IgG1kappa cryoglobulin yielding organized microtubular deposits and glomerulonephritis in the course of chronic lymphocytic leukaemia.
H.R. Galea
,
Franck Bridoux
,
Jean-Claude Aldigier
,
François Paraf
,
Dominique Bordessoule
Article dans une revue
hal-00023688v1
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B cell development arrest upon insertion of a neo gene between JH and Emu: promoter competition results in transcriptional silencing of germline JH and complete VDJ rearrangements.
Laurent Delpy
,
Catherine Decourt
,
Marc Le Bert
,
Michel Cogné
Journal of Immunology, 2002, 169 (12), pp.6875-82
Article dans une revue
hal-00023696v1
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