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Immunoglobulin genes undergo legitimate repair in human B cells not only after cis- but also frequent trans-class switch recombination.
Brice Laffleur
,
Sylvia M. Bardet
,
Armand Garot
,
M Brousse
,
A Baylet
Article dans une revue
hal-01112042v1
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The Eμ enhancer region influences H chain expression and B cell fate without impacting IgVH repertoire and immune response in vivo.
Marie Marquet
,
Armand Garot
,
Sébastien Bender
,
Claire Carrion
,
Pauline Rouaud
Article dans une revue
hal-01110453v1
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Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development.
Aurélien Tinguely
,
Guillaume Chemin
,
Sophie Péron
,
Christophe Sirac
,
Stéphane Reynaud
Article dans une revue
hal-00696497v1
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Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.
Laureline Berthelot
,
Christina Papista
,
Thiago T Maciel
,
Martine Biarnes-Pelicot
,
Emilie Tissandie
Article dans une revue
hal-00903832v1
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A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene.
Rémi Fiancette
,
Pauline Rouaud
,
Christelle Vincent-Fabert
,
Brice Laffleur
,
Virginie Magnone
Article dans une revue
hal-00696493v1
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A myeloma translocation-like model associating CCND1 with the immunoglobulin heavy-chain locus 3' enhancers does not promote by itself B-cell malignancies.
Rémi Fiancette
,
Rada Amin
,
Véronique Truffinet
,
Christelle Vincent-Fabert
,
Nadine Cogné
Article dans une revue
hal-00514237v1
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Genetic background modulates susceptibility to oncogen-driven proliferation and lymphoma occurrence in mice carrying a deregulated c-myc transgene.
Christelle Vincent-Fabert
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Rémi Fiancette
,
Véronique Truffinet
,
Nadine Cogné
,
Michel Cogné
Article dans une revue
hal-00514240v1
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The 3' IgH locus control region is sufficient to deregulate a c-myc transgene and promote mature B cell malignancies with a predominant Burkitt-like phenotype.
Véronique Truffinet
,
Eric Pinaud
,
Nadine Cogné
,
Barbara Petit
,
Laurence Guglielmi
Journal of Immunology, 2007, 179 (9), pp.6033-6042
Article dans une revue
hal-00181178v1
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Interallelic class switch recombination contributes significantly to class switching in mouse B cells.
Stéphane Reynaud
,
Laurent Delpy
,
Laurence Fleury
,
Hei-Lanne Dougier
,
Christophe Sirac
Journal of Immunology, 2005, 174 (10), pp.6176-83
Article dans une revue
hal-00458866v1
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Transcription-dependent somatic hypermutation occurs at similar levels on functional and nonfunctional rearranged IgH alleles.
Laurent Delpy
,
Christophe Sirac
,
Caroline Le Morvan
,
Michel Cogné
Journal of Immunology, 2004, 173 (3), pp.1842-8
Article dans une revue
hal-00023372v1
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The immunoglobulin heavy-chain locus hs3b and hs4 3' enhancers are dispensable for VDJ assembly and somatic hypermutation.
Caroline Le Morvan
,
Eric Pinaud
,
Catherine Decourt
,
Armelle Cuvillier
,
Michel Cogné
Article dans une revue
hal-00023823v1
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B cell development arrest upon insertion of a neo gene between JH and Emu: promoter competition results in transcriptional silencing of germline JH and complete VDJ rearrangements.
Laurent Delpy
,
Catherine Decourt
,
Marc Le Bert
,
Michel Cogné
Journal of Immunology, 2002, 169 (12), pp.6875-82
Article dans une revue
hal-00023696v1
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