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mRNA Lipoplexes with Cationic and Ionizable α-Amino-lipophosphonates: Membrane Fusion, Transfection, mRNA Translation and Conformation
Sohail Akhter
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Paul-Alain Jaffrès
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Chantal Pichon
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Patrick Midoux
Article dans une revue
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Tuneable thermal properties of PTHF-based copolymers by incorporation of epoxide units
Pauline Le Bellec
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Patrick Midoux
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Hervé Cheradame
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Véronique Bennevault
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Philippe Guégan
Article dans une revue
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Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles
Christophe Delehedde
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Luc Even
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Patrick Midoux
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Chantal Pichon
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Federico Perche
Article dans une revue
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LentiRILES, a miRNA-ON Sensor System for Monitoring the Functionality of miRNA in Cancer Biology and Therapy
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Controlled star poly(2-oxazoline)s: Synthesis, characterization
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Nadège Pantoustier
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Intracellular trafficking and functional monitoring of miRNA delivery in glioblastoma using lipopolyplexes and the miRNA-ON RILES reporter system
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Article dans une revue
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Periodic Mesoporous Organosilica Nanoparticles with BOC Group, towards HIFU Responsive Agents
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Article dans une revue
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Co-delivery of NS1 and BMP2 mRNAs to murine pluripotent stem cells leads to enhanced BMP-2 expression and osteogenic differentiation
Pinpin Wang
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Article dans une revue
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Temperature‐Sensitive Amphiphilic Non‐Ionic Triblock Copolymers for Enhanced In Vivo Skeletal Muscle Transfection
Bazoly Rasolonjatovo
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Jérôme Mathé
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Article dans une revue
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Comparative binding and uptake of liposomes decorated with mannose oligosaccharides by cells expressing the mannose receptor or DC-SIGN
Haifei Gao
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Téo Gallego
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Marc Francois-Heude
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Virginie Malard
Article dans une revue
hal-02522179v1
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Gene transfer to skeletal muscle using hydrodynamic limb vein injection: current applications, hurdles and possible optimizations
Yann Thierry Le Guen
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Tony Le Gall
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Patrick Midoux
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Philippe Guégan
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Serge Braun
Article dans une revue
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Improved histidinylated lPEI polyplexes for skeletal muscle cells transfection
Jean-Pierre Gomez
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Guillaume Tresset
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Chantal Pichon
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Patrick Midoux
Article dans une revue
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Amino-acid functionalized porous silicon nanoparticles for the delivery of pDNA
Arnaud Chaix
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Anthony Delalande
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Nikola Knezevic
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Article dans une revue
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Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells
A. Le Moignic
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T. Benvegnu
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L. Lemiègre
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Mathieu Berchel
Article dans une revue
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Poly( N -methylvinylamine)-based copolymers for improved gene transfection
Mathilde Dréan
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Christine Jérôme
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Cristine Gonçalves
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Patrick Midoux
Article dans une revue
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Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety
Kevin van Der Jeught
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Stefaan de Koker
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Lukasz Bialkowski
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Carlo Heirman
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Patrick Tjok Joe
Article dans une revue
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Group quenching and galactic conformity at low redshift
M. Treyer
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Article dans une revue
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Bile Salt Stabilized Vesicles (Bilosomes): A Novel Nano-Pharmaceutical Design for Oral Delivery of Proteins and Peptides
Javed Ahmad
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Saima Amin
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Md. Rizwanullah
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Article dans une revue
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Effect of IL-1β, TNF-α and IGF-1 on trans-endothelial passage of synthetic vectors through an in vitro vascular endothelial barrier of striated muscle
Jean-Pierre Gomez
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Cristine Gonçalves
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Chantal Pichon
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Patrick Midoux
Article dans une revue
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Nanoporous metal organic frameworks as hybrid polymer–metal composites for drug delivery and biomedical applications
Sarwar Beg
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Mahfoozur Rahman
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Atul Jain
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Sumant Saini
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Article dans une revue
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Production of DNA minicircles less than 250 base pairs through a novel concentrated DNA circularization assay enabling minicircle design with NF-κB inhibition activity
Thomas Thibault
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Patrick Baril
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Chantal Pichon
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Patrick Midoux
Article dans une revue
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Synthesis of α-amino-lipophosphonates as cationic lipids or co-lipids for DNA transfection in dendritic cells
Mathieu Berchel
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Sohail Akhter
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Wilfried Berthe
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Cristine Gonçalvez
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Marine Dubuisson
Article dans une revue
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Cationic gas-filled microbubbles for ultrasound-based nucleic acids delivery
Anthony Delalande
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Lucie Pigeon
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Simona Manta
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Matthias Lebertre
Article dans une revue
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Nanotechnology Based Theranostic Approaches in Alzheimer's Disease Management: Current Status and Future Perspective
Javed Ahmad
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Sohail Akhter
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Md. Rizwanullah
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Mohammad Ahmed Khan
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Lucie Pigeon
Article dans une revue
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Peptides mediating DNA transport on microtubules and their impact on non-viral gene transfer efficiency
Patrick Midoux
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Lucie Pigeon
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Cristine Goncalves
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Chantal Pichon
Article dans une revue
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Cationic microbubbles and antibiotic-free miniplasmid for sustained ultrasound–mediated transgene expression in liver
Simona Manta
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Isabelle Lagoutte
Article dans une revue
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Curcumin/poly(2-methyl-2-oxazoline-b-tetrahydrofuran-b-2-methyl-2-oxazoline) formulation: An improved penetration and biological effect of curcumin in F508del-CFTR cell lines
Cristine Gonçalves
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William Même
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Bazoly Rasolonjatovo
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David Gosset
Article dans une revue
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Use of Primary and Secondary Polyvinylamines for Efficient Gene Transfection
Mathilde Dréan
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Antoine Debuigne
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Cristine Gonçalves
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Christine Jérôme
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Patrick Midoux
Article dans une revue
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Toxicity of Inorganic Nanoparticles Used in Targeted Drug Delivery and Other Biomedical Application: An Updated Account on Concern of Biomedical Nanotoxicology
Mohammad Zaki Ahmad
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Sobiya Zafar
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Javed Ahmad
Article dans une revue
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Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines
Thomas Démoulins
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Panagiota Milona
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Pavlos C. Englezou
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Thomas Ebensen
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Kai Schulze
Article dans une revue
hal-01406947v1
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Evidence for plasmid DNA exchange after polyplex mixing
L. Pigeon
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Article dans une revue
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Synthesis of a trimannosylated-equipped archaeal diether lipid for the development of novel glycoliposomes
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Article dans une revue
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Twelfth Annual Meeting of the French Society of Cell and Gene Therapy
Els Verhoeyen
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Patrick Midoux
Article dans une revue
hal-01469045v1
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Engineered Nanoparticles Against MDR in Cancer: The State of the Art and its Prospective
Javed Ahmad
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Mohammad Ahmed Khan
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Muhammad Wahajuddin
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Nigel H. Greig
Article dans une revue
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Synthetic phospholipids and phospho-bola-amphiphiles for nucleic acid delivery
Mathieu Berchel
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Wilfried Berthe
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Sylvie Hernot
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Hélène Couthon
Article dans une revue
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The promise of gene therapy for pancreatic cancer
Georges Vassaux
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Assia Angelova
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Patrick Baril
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Patrick Midoux
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Jean Rommelaere
Article dans une revue
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Intracellular Availability of pDNA and mRNA after Transfection: A Comparative Study among Polyplexes, Lipoplexes, and Lipopolyplexes
Cristine Goncalves
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Sohail Akhter
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Chantal Pichon
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Patrick Midoux
Article dans une revue
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Lipid-based mRNA vaccine delivery systems
Patrick Midoux
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Chantal Pichon
Article dans une revue
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Enhanced Achilles tendon healing by fibromodulin gene transfer
Anthony Delalande
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Marie-Pierre Gosselin
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Arnaud Suwalski
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William Guilmain
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Chloé Leduc
Article dans une revue
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Gene delivery efficiency and intracellular trafficking of novel poly(allylamine) derivatives
Magdalena Wytrwal
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Chloe Leduc
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Michal Sarna
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Cristine Goncalves
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Mariusz Kepczynski
Article dans une revue
hal-01172009v1
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Synthetic vectors for gene delivery: An overview of their evolution depending on routes of administration
Nawal Belmadi
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Patrick Midoux
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Pascal Loyer
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Catherine Passirani
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Chantal Pichon
Article dans une revue
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Poly(2-methyl-2-oxazoline)-b-poly(tetrahydrofuran)-b-poly(2-methyl-2-oxazoline) Amphiphilic Triblock Copolymers: Synthesis, Physicochemical Characterizations, and Hydrosolubilizing Properties
Bazoly Rasolonjatovo
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Jean-Pierre Gomez
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William Même
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Cristine Gonçalves
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Cécile Huin
Article dans une revue
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Efficient gene delivery by sonoporation is associated with microbubble entry into cells and the clathrin-dependent endocytosis pathway
Anthony Delalande
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Chloe Leduc
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Patrick Midoux
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Michiel Postema
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Chantal Pichon
Article dans une revue
hal-03198520v1
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Improved gene transfer with histidine-functionalized mesoporous silica nanoparticles
David Brevet
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Ouahiba Hocine
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Anthony Delalande
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Laurence Raehm
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Clarence Charnay
Article dans une revue
hal-01068026v1
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Different affinity of nuclear factor-kappa B proteins to DNA modified by antitumor cisplatin and its clinically ineffective trans isomer
Jana Kasparkova
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Thomas Thibault
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Hana Kostrhunova
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Jana Stepankova
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Marie Vojtiskova
Article dans une revue
hal-01179156v1
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Improved nuclear delivery of antisense 2′-Ome RNA by conjugation with the histidine-rich peptide H5WYG
Ulysse Asseline
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Cristine Gonçalves
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Chantal Pichon
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Patrick Midoux
Article dans une revue
hal-01175483v1
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Influence of pDNA availability on transfection efficiency of polyplexes in non-proliferative cells.
Benoit Maury
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Cristine Gonçalves
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Guillaume Tresset
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Mehdi Zeghal
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Hervé Cheradame
Article dans une revue
hal-01179393v1
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NF-kB related transgene expression in mouse tibial cranial muscle after pDNA injection followed or not by electrotransfer.
S Mahindhoratep
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BBA - Biochimica et Biophysica Acta, 2014, 1840 (11), pp.3257-3263
Article dans une revue
hal-01179311v1
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Editorial: Current status and prospects on nucleic acid transfer
Tristan Montier
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Chantal Pichon
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Marc Blondel
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Patrick Midoux
Article dans une revue
hal-02135170v1
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Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection
Cristine Gonçalves
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Mathieu Berchel
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Marie-Pierre Gosselin
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Virginie Malard
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Hervé Cheradame
Article dans une revue
hal-01179049v1
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A robust transfection reagent for the transfection of CHO and HEK293 cells and production of recombinant proteins and lentiviral particles - PTG1
Cristine Gonçalves
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Fabian Gross
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Philippe Guégan
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Hervé Cheradame
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Patrick Midoux
Article dans une revue
hal-01179065v1
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Trimethylarsonium-Based Cationic Phospholipids for Gene Delivery
Mathieu Berchel
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Stéphanie Le Corre
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Tony Le Gall
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Hélène Couthon
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Jean-Pierre Haelters
Article dans une revue
hal-02070718v1
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Exogenous mRNA delivery and bioavailability in gene transfer mediated by piggyBac transposition
Solenne Bire
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David Gosset
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Gwenhael Jegot
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Patrick Midoux
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Chantal Pichon
Article dans une revue
hal-01129780v1
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Interaction studies of muts and mutl with DNA containing the major cisplatin lesion and its mismatched counterpart under equilibrium and nonequilibrium conditions.
Yuliya Sedletska
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Françoise Culard
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Patrick Midoux
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Jean-Marc Malinge
Article dans une revue
hal-00874890v1
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Poly- l -Lysine Compacts DNA, Kills Bacteria, and Improves Protease Inhibition in Cystic Fibrosis Sputum
Alice Dubois
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Patrick Midoux
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Delphine Gras
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Mustapha Si-Tahar
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Deborah Brea
Article dans une revue
hal-02070798v1
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An E3-14.7K Peptide that Promotes Microtubules-Mediated Transport of Plasmid DNA Increases Polyplexes Transfection Efficiency.
Lucie Pigeon
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Cristine Gonçalves
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David Gosset
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Chantal Pichon
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Patrick Midoux
Article dans une revue
hal-00840172v1
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Sonoporation: mechanistic insights and ongoing challenges for gene transfer
Anthony Delalande
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Spiros Kotopoulis
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Michiel Postema
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Patrick Midoux
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Chantal Pichon
Article dans une revue
hal-03195625v1
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RILES, a novel method for temporal analysis of the in vivo regulation of miRNA expression.
Safia Ezzine
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Georges Vassaux
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Bruno Pitard
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Benoit Barteau
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Jean-Marc Malinge
Article dans une revue
hal-00874881v1
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Ability of plasmid DNA complexed with histidinylated lPEI and lPEI to cross in vitro lung and muscle vascular endothelial barriers
Jean-Pierre Gomez
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Chantal Pichon
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Patrick Midoux
Article dans une revue
hal-02070843v1
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Ultrasound and microbubble-assisted gene delivery: recent advances and ongoing challenges
Anthony Delalande
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Michiel Postema
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Nathalie Mignet
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Patrick Midoux
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Chantal Pichon
Article dans une revue
hal-03193228v1
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Gene transfer by chemical vectors, and endocytosis routes of polyplexes, lipoplexes and lipopolyplexes in a myoblast cell line.
Ludivine Billiet
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Jean-Pierre Gomez
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Mathieu Berchel
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Paul-Alain Jaffres
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Tony Le Gall
Article dans une revue
hal-00721795v1
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Gene transfer by histidylated lipopolyplexes: A dehydration method allowing preservation of their physicochemical parameters and transfection efficiency
Federico Perche
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Olivier Lambert
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Mathieu Berchel
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Paul-Alain Jaffres
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Chantal Pichon
Article dans une revue
hal-02995807v1
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Ultrasound and microbubble-assisted gene delivery: recent advances and ongoing challenges.
Anthony Delalande
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Michiel Postema
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Nathalie Mignet
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Patrick Midoux
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Chantal Pichon
Ther Deliv, 2012, 3 (10), pp.1199-1215
Article dans une revue
hal-00817350v1
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Lipophosphonate/lipophosphoramidates: a family of synthetic vectors efficient for gene delivery.
Mathieu Berchel
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Tony Le Gall
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Hélène Couthon
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Jean-Pierre Haelters
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Tristan Montier
Article dans une revue
hal-00721772v1
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New Lipo-Phosphoramidates for Gene Delivery
Paul-Alain Jaffres
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Aurore Fraix
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Christophe Lorilleux
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Mathieu Berchel
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Hélène Couthon
Article dans une revue
hal-00614938v1
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Supramolecular assemblies of histidinylated α-cyclodextrin in the presence of DNA scaffold during CDplexes formation.
Véronique Bennevault-Celton
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Olivier Martin
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Chantal Pichon
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Philippe Guégan
Article dans une revue
hal-00720527v1
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Ultrasound and microbubble-assisted gene delivery in Achilles tendons: long lasting gene expression and restoration of fibromodulin KO phenotype
Anthony Delalande
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Ayache Bouakaz
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Gilles Renault
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Flore Tabareau
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Spiros Kotopoulis
Article dans une revue
hal-03195121v1
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Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes.
Federico Perche
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David Gosset
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Marie-Laure Miramon
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Jean-Jacques Yaouanc
Article dans une revue
hal-00753554v1
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Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA.
Federico Perche
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Thierry Benvegnu
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Mathieu Berchel
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Loic Lebegue
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Chantal Pichon
Article dans une revue
hal-00754373v1
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Histidinylated linear PEI: a new efficient non-toxic polymer for gene transfer.
Emilie Bertrand
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Cristine Gonçalves
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Ludivine Billiet
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Jean Pierre Gomez
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Chantal Pichon
Article dans une revue
hal-00720539v1
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Modular Construction of Fluorescent Lipophosphoramidates by Click Chemistry
Mathieu Berchel
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Jean-Piere Haelters
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Hélène Couthon
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Laure Burel-Deschamps
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Patrick Midoux
Article dans une revue
hal-00720537v1
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Chemical vectors for gene delivery: uptake and intracellular trafficking
Chantal Pichon
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Ludivine Billiet
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Patrick Midoux
Article dans une revue
hal-00602488v1
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Uptake of Functionalized Mesoporous Silica Nanoparticles by Human Cancer Cells
Matthieu Fisichella
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Hinda Dabboue
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Sanjib Bhattacharyya
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Gerald Lelong
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Marie-Louise Saboungi
Article dans une revue
hal-00529333v1
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Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles
Arnaud Suwalski
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Hinda Dabboue
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Anthony Delalande
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Sabine F. Bensamoun
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Francis Canon
Article dans une revue
hal-00529475v1
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Ultrasound-assisted microbubbles gene transfer in tendons for gene therapy
Anthony Delalande
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Michel-Francis Bureau
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Patrick Midoux
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Ayache Bouakaz
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Chantal Pichon
Article dans une revue
hal-00529321v1
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Transient transmembrane release of green fluorescent proteins with sonoporation
K. Kaddur
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IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2010, 57 (7), pp.1558-1567. ⟨10.1109/TUFFC.2010.1586⟩
Article dans une revue
hal-00529340v1
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Histidine-rich peptide: evidence for a single zinc-binding site on H5WYG peptide that promotes membrane fusion at neutral pH
Corinne Bure
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Agnès F. Delmas
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Chantal Pichon
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Patrick Midoux
Article dans une revue
hal-00521834v1
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An optimized extended DNA kappa B site that enhances plasmid DNA nuclear import and gene expression
Cristine Gonçalves
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Maryvonne Ardourel
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Martine Decoville
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Gilles Breuzard
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Patrick Midoux
Article dans une revue
hal-00522437v1
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Comparative gene transfer between cationic and thiourea lipoplexes
Marie Breton
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Jeanne Leblond
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Johanne Seguin
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Patrick Midoux
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Daniel Scherman
Article dans une revue
hal-02512540v1
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Involvement of histidines 11, 15 and 19 in the binding of zinc to the fusogenic H5WYG peptide
Corinne Bure
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Chantal Pichon
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Patrick Midoux
Article dans une revue
hal-00521851v1
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Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers
Patrick Midoux
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Chantal Pichon
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Jean-Jacques Yaouanc
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Paul-Alain Jaffres
Article dans une revue
hal-00525108v1
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Glycofection: The Ubiquitous Roles of Sugar Bound on Glycoplexes
Valerie Boutin
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Alain Legrand
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Roger Mayer
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Maurice Nachtigal
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Michel Monsigny
Article dans une revue
hal-02138035v1
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Recent advances in gene delivery with ultrasound and microbubbles
Chantal Pichon
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Kadija Kaddur
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Patrick Midoux
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François Tranquart
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Ayache Bouakaz
Article dans une revue
hal-00518203v1
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Nuclear delivery of NFkappaB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging.
Gilles Breuzard
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Magdalena Tertil
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Cristine Gonçalves
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Hervé Cheradame
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Philippe Géguan
Article dans une revue
hal-00408004v1
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Synthesis and transfection activity of new cationic phosphoramidate lipids: High efficiency of an imidazolium derivative
M. Mevel
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Gilles Breuzard
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J.-J. Yaouanc
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J.-C. Clement
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P. Lehn
Article dans une revue
hal-00518184v1
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Extraction of green fluorescent proteins with sonoporation
Kadija Kaddur
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Anthony Delalande
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François Tranquart
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Patrick Midoux
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Chantal Pichon
Article dans une revue
hal-02128161v1
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Cationic Lipids Based on Phosphonate and Phosphoramidate Chemistry: Synthesis and Application to Gene Therapy
Mathieu Mével
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Jean-Jacques Yaouanc
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Pascal Laurent
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Claude Clément
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Dominique Cartier
Article dans une revue
hal-01580434v1
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Polymer-Based Gene Delivery: A Current Review on the Uptake and Intracellular Trafficking of Polyplexes
Patrick Midoux
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Gilles Breuzard
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Jean-Pierre Gomez
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Chantal Pichon
Current Gene Therapy, 2008, 8 (5), pp.335-352
Article dans une revue
hal-00518197v1
|
|
Novel neutral imidazole-lipophosphoramides for transfection assays
M. Mevel
,
C. Neveu
,
Cristine Goncalves
,
J.-J. Yaouanc
,
Chantal Pichon
Article dans une revue
hal-00518192v1
|
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mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes.
M. Mockey
,
E. Bourseau
,
V. Chandrashekhar
,
A. Chaudhuri
,
S. Lafosse
Article dans une revue
hal-00318514v1
|
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mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes
M. Mockey
,
E Bourseau
,
V Chandrashekhar
,
A. Chaudhuri
,
S. Lafosse
Article dans une revue
hal-03065277v1
|
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Intracellular trafficking and nuclear import of polyplexes by FRET coupled with cellular imaging
Gilles Breuzard
,
M. Tertil
,
Chantal Pichon
,
Patrick Midoux
Human Gene Therapy, 2007, 18, pp.1048
Article dans une revue
hal-00275215v1
|
|
mRNA transfection of dendritic cells: synergistic effect of ARCA mRNA capping with Poly(A) chains in cis and in trans for a high protein expression level
M. Mockey
,
C. Goncalves
,
F.P. Dupuy
,
F.M. Lemoine
,
C. Pichon
Article dans une revue
hal-00088921v1
|
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DNA/cationic polymer complex attachment on a human vascular endothelial cell monolayer exposed to a steady laminar flow
Eric Mennesson
,
Patrick Erbacher
,
Mateusz Kuzak
,
Claudine Kieda
,
Patrick Midoux
Article dans une revue
hal-00112894v1
|
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Transfection efficiency and uptake process of polyplexes in human lung endothetial cells: a comparative study in non-polarized and polarized cells
E. Mennesson
,
P. Erbacher
,
V. Piller
,
C. Kieda
,
P. Midoux
The Journal of Gene Medicine, 2005, 7, pp.729-738
Article dans une revue
hal-00088642v1
|
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Non-viral vectors in cystic fibrosis gene therapy: progress and challenges
T. Montier
,
P. Delépine
,
C. Pichon
,
C. Férec
,
D.J. Porteous
Trends in biotechnology., 2004, 22, pp.586-592
Article dans une revue
hal-00088424v1
|
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Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependant pathway impair the transfection efficiency into human hepatocarcinoma cells
C. Goncalves
,
E. Mennesson
,
R. Fuchs
,
Gorvel J.P.
,
Patrick Midoux
Molecular Therapy, 2004, 10, pp.373-385
Article dans une revue
hal-00113047v1
|
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Optimization of in vitro vascular cell transfection with non-viral vectors for in vivo applications
Ibrahim Elmadbouh
,
Patrick Rossignol
,
Olivier Meilhac
,
Roger Vranckx
,
Chantal Pichon
The Journal of Gene Medicine, 2004, 6 (10), pp.1112-1124
Article dans une revue
hal-00014241v1
|
|
An efficient and facile nitration of phenols with nitric acid/zinc chloride under ultrasonic conditions
A. Kamal
,
B.A. Kumar
,
M. Arifuddin
,
P. Midoux
Ultrasonics Sonochemistry, 2004, 11, pp.455-457
Article dans une revue
hal-00088378v1
|
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On the gene delivery efficacies of pH-sensitive cationic lipids via endosomal protonation: a chemical biology investigation
R.S. Singh
,
C. Gonçalves
,
P. Sandrin
,
C. Pichon
,
P. Midoux
Chemistry & biology, 2004, 11, pp.713-723
Article dans une revue
hal-00088426v1
|
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Poly[Lys-(AEDTP)]: A Cationic Polymer That Allows Dissociation of pDNA/Cationic Polymer Complexes in a Reductive Medium and Enhances Polyfection
Chantal Pichon
,
Eric Le Cam
,
Brigitte Guérin
,
Dominique Coulaud
,
Etienne Delain
Article dans une revue
hal-03065338v1
|
|
Zinc improves gene transfer mediated by DNA/cationic polymer complexes
Chantal Pichon
,
Brigitte Guérin
,
Matthieu M. Refregiers
,
Christine Gonçalves
,
Paul Vigny
Article dans une revue
hal-01596013v1
|
|
Intracellular processing and stability of DNA complexed with histidylated polylysine conjugates
Christine Gonçalves
,
Chantal Pichon
,
Brigitte Guérin
,
Patrick Midoux
Article dans une revue
hal-02135970v1
|
|
Histidine containing peptides and polypeptides as nucleic acid vectors.
Patrick Midoux
,
Eric Le Cam
,
Dominique Coulaud
,
Etienne Delain
,
Chantal Pichon
Article dans une revue
hal-03065331v1
|
|
Single histidine residue in head-group region is sufficient to impart remarkable gene transfection properties to cationic lipids: evidence for histidine-mediated membrane fusion at acidic pH
V Kumar
,
Chantal Pichon
,
M. Refregiers
,
B Guerin
,
P. Midoux
Article dans une revue
hal-01596052v1
|
|
Nonviral gene transfer into primary cultures of human and porcine mesothelial cells.
J Ohan
,
M.A Gilbert
,
G Leseche
,
Y Panis
,
P. Midoux
In Vitro Cellular & Developmental Biology - Animal, 2001, 37 (7), pp.402-7
Article dans une revue
hal-02161118v1
|
|
Histidine-rich peptides and polymers for nucleic acids delivery.
Chantal Pichon
,
C Gonçalves
,
P. Midoux
Advanced Drug Delivery Reviews, 2001, 53 (1), pp.75-94
Article dans une revue
hal-02135973v1
|
|
Histidylated polylysine as DNA vector: elevation of the imidazole protonation and reduced cellular uptake without change in the polyfection efficiency of serum stabilized negative polyplexes.
M Bello Roufaï
,
P. Midoux
Article dans une revue
hal-02161122v1
|
|
Efficient Gene Transfer into Human Normal and Cystic Fibrosis Tracheal Gland Serous Cells with Synthetic Vectors
J.C Allo
,
Patrick Midoux
,
Marc Merten
,
Evelyne Souil
,
Joanna Lipecka
Article dans une revue
hal-02161132v1
|
|
Histidylated oligolysines increase the transmembrane passage and the biological activity of antisense oligonucleotides
Chantal Pichon
,
Mahajoub Bello Roufaï
,
Michel Monsigny
,
Patrick Midoux
Article dans une revue
hal-02135979v1
|
|
Histidylated polylysine as a synthetic vector for gene transfer into immortalized cystic fibrosis airway surface and airway gland serous cells
Isabelle Fajac
,
J.C Allo
,
Evelyne Souil
,
Marc Merten
,
Chantal Pichon
Article dans une revue
hal-02135988v1
|
|
Spacer length dependence on the efficiency of dimeric anionic peptides in gene transfer by glycosylated polylysine/plasmid complexes.
I. Freulon
,
M. Monsigny
,
P. Midoux
,
R. Mayer
Article dans une revue
hal-02161127v1
|
|
GlycofectionTM in the presence of anionic fusogenic peptides: a study of the parameters affecting the peptide-mediated enhancement of the transfection efficiency
Antoine Kichler
,
Isabelle Freulon
,
Valerie Boutin
,
Roger Mayer
,
Michel Monsigny
Article dans une revue
hal-02161144v1
|
|
Efficient Gene Transfer by Histidylated Polylysine/pDNA Complexes
Patrick Midoux
,
Michel Monsigny
Article dans une revue
hal-02161145v1
|
|
Sugar-Mediated Uptake of Glycosylated Polylysines and Gene Transfer into Normal and Cystic Fibrosis Airway Epithelial Cells
Isabelle Fajac
,
Pascale Briand
,
Michel Monsigny
,
Patrick Midoux
Article dans une revue
hal-02161152v1
|
|
Glycotargeting: the preparation of glyco-amino acids and derivatives from unprotected reducing sugars.
M Monsigny
,
C. Quétard
,
S. Bourgerie
,
D. Delay
,
Chantal Pichon
Biochimie, 1998, 80 (2), pp.99-108
Article dans une revue
hal-02136005v1
|
|
Novel Glycosynthons for Glycoconjugate Preparation: Oligosaccharylpyroglutamylanilide Derivatives
Christophe Quétard
,
Sylvain Bourgerie
,
Nadia Normand-Sdiqui
,
Roger Mayer
,
Gérard Strecker
Article dans une revue
hal-02161157v1
|
|
Membrane Permeabilization and Efficient Gene Transfer by a Peptide Containing Several Histidines
Patrick Midoux
,
Antoine Kichler
,
Valerie Boutin
,
Jean-Claude Maurizot
,
Michel Monsigny
Article dans une revue
hal-02161162v1
|
|
Specific Gene Transfer Based on Biotinylated and Gluconoylated Polylysine/Plasmid Complexes
Patrick Erbacher
,
Annie Claude Roche
,
Michel Monsigny
,
Patrick Midoux
Article dans une revue
hal-02161332v1
|
|
Glycosylated Polylysines. Nonviral vectors for gene transfer into cystic fibrosis airway epithelial cells.
Wouter Kollen
,
Patrick Erbacher
,
Patrick Midoux
,
Annie-Claude Roche
,
Michel Monsigny
Article dans une revue
hal-02161319v1
|
|
The reduction of the positive charges of polylysine by partial gluconoylation increases the transfection efficiency of polylysine/DNA complexes
Patrick Erbacher
,
Annie Claude Roche
,
Michel Monsigny
,
Patrick Midoux
Article dans une revue
hal-02161372v1
|
|
Cytosolic and Nuclear Delivery of Oligonucleotides Mediated by an Amphiphilic Anionic Peptide
Chantal Pichon
,
Isabelle Freulon
,
Patrick Midoux
,
Roger Mayer
,
Michel Monsigny
Article dans une revue
hal-02136009v1
|
|
Fluorescent labelling of unmodified phosphorothioate oligodeoxynucleotides: Synthesis and characterization
A.J. Stewart
,
Chantal Pichon
,
Patrick Midoux
,
R. Mayer
,
Michel Monsigny
New Journal of Chemistry, 1997, 21 (1), pp.87-98
Article dans une revue
hal-02161369v1
|
|
Expression of a mannose/fucose membrane lectin on human dendritic cells
Alexandre Avraméas
,
Dorian Mcilroy
,
Anne Hosmalin
,
Brigitte Autran
,
Patrice Debré
Article dans une revue
hal-02161396v1
|
|
Gene Transfer by DNA/Glycosylated Polylysine Complexes into Human Blood Monocyte-Derived Macrophages
Patrick Erbacher
,
Marie-Thérèse Bousser
,
Jacques Raimond
,
Michel Monsigny
,
Patrick Midoux
Article dans une revue
hal-02161390v1
|
|
Gluconoylated and Glycosylated Polylysines As Vectors for Gene Transfer into Cystic Fibrosis Airway Epithelial Cells
Wouter Kollen
,
Patrick Midoux
,
Patrick Erbacher
,
Alex Yip
,
Annie Claude Roche
Article dans une revue
hal-02161378v1
|
|
Putative Role of Chloroquine in Gene Transfer into a Human Hepatoma Cell Line by DNA/Lactosylated Polylysine Complexes
Patrick Erbacher
,
Annie Claude Roche
,
Michel Monsigny
,
Patrick Midoux
Article dans une revue
hal-02161382v1
|
|
Enhanced biological activity of antisense oligonucleotides complexed with glycosylated poly-L-lysine.
A. Stewart
,
Chantal Pichon
,
L Meunier
,
P Midoux
,
M. Monsigny
Molecular Pharmacology, 1996, 50 (6), pp.1487-94
Article dans une revue
hal-02136015v1
|
|
Membrane permeabilization by α-helical peptides: a flow cytometry study
Patrick Midoux
,
Roger Mayer
,
Michel Monsigny
Article dans une revue
hal-02161407v1
|
|
Glycosylated polylysine/DNA complexes: gene transfer efficiency in relation with the size and the sugar substitution level of glycosylated polylysines and with the plasmid size.
P Erbacher
,
A.C. Roche
,
M. Monsigny
,
P. Midoux
Article dans une revue
hal-02161414v1
|
|
Inhibition of Human Mammary Cell Line Proliferation by Membrane Lectin-Mediated Uptake of Ha- ras Antisense Oligodeoxynucleotide
Nadia Sdiqui
,
Khalil Arar
,
Patrick Midoux
,
Roger Mayer
,
Michel Monsigny
Article dans une revue
hal-02161404v1
|
|
Glycoconjugates as carriers for specific delivery of therapeutic drugs and genes
Michel Monsigny
,
Annie-Claude Roche
,
Patrick Midoux
,
Roger Mayer
Article dans une revue
hal-02163748v1
|
|
Perspectives ex vivo et in vivo pour la thérapie génique, de la transfection sélective à l'aide de complexes plasmide-polylysine ciblés
M. Monsigny
,
P. Midoux
,
A.C. Roche
Article dans une revue
hal-02163755v1
|
|
Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells
Patrick Midoux
,
Christina Mendes
,
Alain Legrand
,
Jacques Raimond
,
Roger Mayer
Article dans une revue
hal-02138456v1
|
|
Endocytosis of alpha 1-acid glycoprotein variants by human monocytic lineage cells.
V. Carpentier
,
Patrick Midoux
,
M. Monsigny
,
A.C. Roche
Article dans une revue
hal-02161453v1
|
|
Drug targeting: synthesis and endocytosis of oligonucleotide-neoglycoprotein conjugates
N Bonfils
,
C. Depierreux
,
P. Midoux
,
N.T. Thuong
,
M. Monsigny
Article dans une revue
hal-02161479v1
|
|
Uptake by macrophages of a biotinylated oligo-alpha-deoxythymidylate by using mannosylated streptavidin.
E Bonfils
,
C. Mendes
,
A.C. Roche
,
M. Monsigny
,
P. Midoux
Article dans une revue
hal-02161474v1
|
|
Activation of mouse macrophages by muramyl dipeptide coupled with an anti-macrophage monoclonal antibody.
Patrick Midoux
,
A. Martin
,
B Collet
,
M. Monsigny
,
A.C. Roche
Article dans une revue
hal-02161456v1
|
|
Characterization and isolation of an intracellular D-mannose-specific receptor from human promyelocytic HL60 cells.
V Pimpaneau
,
Patrick Midoux
,
M. Monsigny
,
A.C. Roche
Article dans une revue
hal-02162388v1
|
|
Production of macrophage-derived cytotoxic factor by N-[3-[(carbamoylmethyl)thio]propionylated] neoglycoproteins.
P Breton
,
Patrick Midoux
,
Christian Petit
,
M Bousser
,
A.C Roche
Bioconjugate Chemistry, 1991, 2 (1), pp.16-8
Article dans une revue
hal-02162393v1
|
|
Benzoxazinone kanamycin A conjugate. A new fluorescent probe suitable to detect mycoplasmas in cell culture.
M Monsigny
,
Patrick Midoux
,
C. Depierreux
,
C Bebear
,
M.T Le Bris
Article dans une revue
hal-02163189v1
|
|
Drug targeting: Anti-HSV-1 activity of mannosylated polymer-bound 9-(2-phosphonylmethoxyethyl)adenine
Patrick Midoux
,
Eric Negre
,
Annie-Claude Roche
,
Roger Mayer
,
Michel Monsigny
Article dans une revue
hal-02163192v1
|
|
Benzoxazinone derivatives: new fluorescent probes for two-color flow cytometry analysis using one excitation wavelength.
M Monsigny
,
Patrick Midoux
,
M.T Le Bris
,
A.C Roche
,
B Valeur
Article dans une revue
hal-02163198v1
|
|
Macrophage antigens associated with adhesion: identification by a monoclonal antibody specific for Lewis lung carcinoma cells.
Patrick Midoux
,
Christian Petit
,
P Pellen
,
L Toujas
,
M. Monsigny
Article dans une revue
hal-02163384v1
|
|
Endocytosis of alpha 1-acid glycoprotein variants and of neoglycoproteins containing mannose derivatives by a mouse hybridoma cell line (2C11-12). Comparison with mouse peritoneal macrophages.
V Pimpaneau
,
Patrick Midoux
,
Geoffroy Durand
,
P de Baetselier
,
M. Monsigny
Article dans une revue
hal-02163197v1
|
|
Muramyl dipeptide bound to poly-L-lysine substituted with mannose and gluconoyl residues as macrophage activators.
D Derrien
,
Patrick Midoux
,
Christian Petit
,
E. Negre
,
R. Mayer
Article dans une revue
hal-02163397v1
|
|
Characterization and biological implications of membrane lectins in tumor, lymphoid and myeloid cells.
M Monsigny
,
Annie Claude Roche
,
C. Kieda
,
P. Midoux
,
A Obrénovitch
Article dans une revue
hal-02163758v1
|
|
Endogenous Lectins and Drug Targeting
M. Monsigny
,
A.C Roche
,
P. Midoux
Article dans une revue
hal-02163799v1
|
|
Characterization of membrane lectins in human colon carcinoma cells by flow cytofluorometry, drug targeting and affinity chromatography.
Hj Gabius
,
R Engelhardt
,
T Hellmann
,
Patrick Midoux
,
M. Monsigny
Anticancer Research, 1987, 7 (1), pp.109-112
Article dans une revue
hal-02163405v1
|
|
Quantitation of the binding, uptake, and degradation of fluoresceinylated neoglycoproteins by flow cytometry
Patrick Midoux
,
Annie-Claude Roche
,
Michel Monsigny
Article dans une revue
hal-02163401v1
|
|
Analysis of sugar-binding sites in mammalian cell nuclei by quantitative flow microfluorometry.
A Sève
,
J. Hubert
,
D. Bouvier
,
C. Bourgeois
,
P. Midoux
Proceedings of the National Academy of Sciences of the United States of America, 1986, 83 (16), pp.5997-6001. ⟨10.1073/pnas.83.16.5997⟩
Article dans une revue
hal-02163583v1
|
|
Estimation of the degradation of endocytosed material by flow cytofluorometry using two neoglycoproteins containing different numbers of fluorescein molecules.
Patrick Midoux
,
A.C Roche
,
M. Monsigny
Biology of the Cell, 1986, 58 (3), pp.221-225
Article dans une revue
hal-02163590v1
|
|
Membrane lectins on human monocytes. Maturation-dependent modulation of 6-phosphomannose and mannose receptors.
Annie-Claude Roche
,
Patrick Midoux
,
Philippe Bouchard
,
Michel Monsigny
Article dans une revue
hal-02163594v1
|
|
Monoclonal antibodies (IgM) against a murine carcinoma, Lewis lung carcinoma (3LL): production, purification and in vitro selectivity.
Patrick Midoux
,
Annie-Claude Roche
,
M. Monsigny
Article dans une revue
hal-02163712v1
|
|
Uptake of neoglycoproteins via membrane lectin(s) of L1210 cells evidenced by quantitative flow cytofluorometry and drug targeting.
M. Monsigny
,
Annie-Claude Roche
,
P. Midoux
Article dans une revue
hal-02163609v1
|
|
Fluorescence quenching of tryptophan by trifluoroacetamide
Patrick Midoux
,
Philippe Wahl
,
Jean-Claude Auchet
,
Michel Monsigny
Article dans une revue
hal-02163704v1
|
|
Tumor localization of Lewis lung carcinoma with radiolabeled monoclonal antibodies
Patrick Midoux
,
Thierry Maillet
,
Fabienne Therain
,
Michel Monsigny
,
Annie-Claude Roche
Article dans une revue
hal-02163698v1
|
|
Selective macrophage activation by muramyldipeptide bound to monoclonal antibodies specific for mouse tumor cells.
Annie Claude Roche
,
P Bailly
,
Patrick Midoux
,
M. Monsigny
Cancer Immunology, Immunotherapy, 1984, 18 (3), pp.155-159
Article dans une revue
hal-02163604v1
|
|
The binding of monosaccharides to wheat germ agglutinin: Fluorescence and NMR investigations
P. Midoux
,
J.P Grivet
,
F. Delmotte
,
M. Monsigny
Article dans une revue
hal-02163716v1
|
|
Sugar-specific endocytosis of glycoproteins by Lewis lung carcinoma cells
A.C Roche
,
M. Barzilay
,
P. Midoux
,
S. Junqua
,
N. Sharon
Article dans une revue
hal-02163725v1
|
|
Protein-sugar interactions: Environmental effect on the fluorescence of O-(4-methylumbelliferyl)-glycosides
P. Midoux
,
F. Delmotte
,
J.Ph Grivet
,
M. Monsigny
Article dans une revue
hal-02163727v1
|
|
Lectin-sugar interactions: the binding of 1- O -methyl-di- N -trifluoroacetyl-β-chitobioside to wheat germ agglutinin
M Midoux
,
J.-Ph. Grivet
,
M. Monsigny
,
P. Midoux
Article dans une revue
hal-02163732v1
|