Hélène BRIGNOT

Identifiants chercheurs

IdHAL :

1203950

ORCID :

0000-0002-0584-3299

Publications

Article dans une revue (32)

Determination of the Optimal Method for Measuring Malondialdehyde in Human Saliva Hélène Brignot,Camille Rayot,Guillaume Buiret,Thierry Thomas-Danguin,Gilles Feron MethodsX, 2025, 14, pp.103070. ⟨10.1016/j.mex.2024.103070⟩ Article dans une revue hal-04814761v1
Unravelling the interplay between the oral microbiota and the salivary environment: links with body mass index and taste perception Paula Calvo López-Dávalos,Eric Neyraud,Teresa Requena,Hélène Brignot,M Ángeles Pozo-Bayónet al. Food Research International, 2025, 221 (Part 1), pp.117077. ⟨10.1016/j.foodres.2025.117077⟩ Article dans une revue hal-05217584v1
Altérations gustatives et salivaires chez des patients atteints de cancer des voies aérodigestives supérieures : étude longitudinale prospective Guillaume Buiret,Thierry Thomas-Danguin,Hélène Brignot,Gilles Feron Cahiers de Nutrition et de Diététique, 2025, 60 (3), pp.183-192. ⟨10.1016/j.cnd.2025.03.001⟩ Article dans une revue hal-05049745v1
In Vitro Monitoring of Taste Compound Release During Chewing According to Process‐Related Parameters of the Food Raphaël Monod,Ana Carolina Conti,Emmanuel Denimal,Chantal Septier,Bérénice Houinsou-Houssouet al. Journal of Texture Studies, 2025, 56 (6), pp.e70053. ⟨10.1111/jtxs.70053⟩ Article dans une revue hal-05405892v1
Evaluating the etiology of metallic taste during head and neck cancer treatments: a study of facial and glossopharyngeal nerve interactions Guillaume Buiret,Hélène Brignot,Chantal Septier,Gilles Feron,Thierry Thomas-Danguin Neuroscience, 2025, 580, pp.80-87. ⟨10.1016/j.neuroscience.2025.06.038⟩ Article dans une revue hal-05138490v1
Development of New Models of Oral Mucosa to Investigate the Impact of the Structure of Transmembrane Mucin-1 on the Mucosal Pellicle Formation and Its Physicochemical Properties Clément Nivet,Irma Custovic,Laure Avoscan,Floris Bikker,Aline Bonnotteet al. Biomedicines, 2024, 12 (1), pp.139. ⟨10.3390/biomedicines12010139⟩ Article dans une revue hal-04395339v1
The Nutritional Impact of Metallic Taste in Head and Neck Cancer Patients: Explorations and Clinical Implications Guillaume Buiret,Hélène Brignot,Chantal Septier,Thierry Thomas-Danguin,Feron Gilles Supportive Care in Cancer, 2024, 32 (10), pp.651. ⟨10.1007/s00520-024-08854-z⟩ Article dans une revue hal-04575323v1
Phenols and saliva effect on virgin olive oil aroma release: A chemical and sensory approach Enrique Jacobo Díaz-Montaña,Hélène Brignot,Ramón Aparicio-Ruiz,Thierry Thomas-Danguin,María Teresa Morales Food Chemistry, 2024, 437 (Pt 1), pp.137855. ⟨10.1016/j.foodchem.2023.137855⟩ Article dans une revue hal-04313664v1
Salivary cholesterol level does not reflect cholesterolemia in children with heterozygous familial hypercholesterolemia Marianne Fricaudet,Mathilde Di Filippo,Philippe Moulin,Séverine Nony,Marie Anais Peronet al. Nutrition Clinique et Métabolisme, 2023, 37 (7), pp.162-167. ⟨10.1016/j.nupar.2023.04.003⟩ Article dans une revue hal-04158424v1
Astringency sensitivity to tannic acid: effect of ageing and salivary flow Mei Wang,Chantal Septier,Hélène Brignot,Christophe Martin,Gilles Feronet al. Molecules, 2022, 27 (5), pp.1617. ⟨10.3390/molecules27051617⟩ Article dans une revue hal-03611747v1
Role of human salivary enzymes in bitter taste perception Mathieu Schwartz,Hélène Brignot,Gilles Feron,Thomas Hummel,Yunmeng Zhuet al. Food Chemistry, 2022, 386, pp.132798. ⟨10.1016/j.foodchem.2022.132798⟩ Article dans une revue hal-03712655v1
The association between changes of gustatory function and changes of salivary parameters: A pilot study Yunmeng Zhu,Gilles Feron,Dorothee von Koskull,Fabrice Neiers,Hélène Brignotet al. Clinical Otolaryngology, 2021, 46 (3), pp.538-545. ⟨10.1111/COA.13705⟩ Article dans une revue hal-03131296v1
Perspectives on astringency sensation: An alternative hypothesis on the molecular origin of astringency Francis Canon,Christine Belloir,Eric Bourillot,Hélène Brignot,Loïc Briandet al. Journal of Agricultural and Food Chemistry, 2021, 69 (13), pp.3822-3826. ⟨10.1021/acs.jafc.0c07474⟩ Article dans une revue hal-03173490v1
Rôle de la salive dans la perception sensorielle et introduction aux pratiques analytiques Hélène Brignot,Gilles Feron Cahiers de Nutrition et de Diététique, 2021, 56 (4), pp.234-248. ⟨10.1016/j.cnd.2021.04.005⟩ Article dans une revue (article de synthèse) hal-03341399v1
Longitudinal analysis of the salivary metabolome of breast-fed and formula-fed infants over the first year of life Eric Neyraud,Camille Schwartz,Hélène Brignot,Isabelle Jouanin,Marie Tremblay-Francoet al. Metabolomics, 2020, 16 (3), ⟨10.1007/s11306-020-01661-7⟩ Article dans une revue hal-02558354v1
Proteomic characterization of the mucosal pellicle formed in vitro on a cellular model of oral epithelium Gianluigi Cabiddu,Pauline Maes,Franck Hyvrier,Alessandra Olianas,Barbara Manconiet al. Journal of Proteomics, 2020, 222, pp.103797. ⟨10.1016/j.jprot.2020.103797⟩ Article dans une revue hal-02570553v1
How are macronutrient intake, BMI, ethnicity, age, and gender related to the composition of unstimulated saliva? A case study Ana Carolina Mosca,Markus Stieger,Eric Neyraud,Hélène Brignot,Anne van de Wielet al. Journal of Texture Studies, 2019, 50 (1), pp.53-61. ⟨10.1111/jtxs.12362⟩ Article dans une revue hal-02622839v1
Oral lipolysis and its association with diet and the perception and digestion of lipids: A systematic literature review Hélène Brignot,Gilles Feron Archives of Oral Biology, 2019, 108, pp.104550. ⟨10.1016/j.archoralbio.2019.104550⟩ Article dans une revue (article de synthèse) hal-02619465v1
Author Correction: Obese Subjects With Specific Gustatory Papillae Microbiota and Salivary Cues Display an Impairment to Sense Lipids Philippe Besnard,Jeffrey E. Christensen,Hélène Brignot,Arnaud Bernard,Patricia Passilly-Degraceet al. Scientific Reports, 2018, 8 (1), pp.9773. ⟨10.1038/s41598-018-27701-w⟩ Article dans une revue hal-02055830v1
Obese Subjects With Specific Gustatory Papillae Microbiota and Salivary Cues Display an Impairment to Sense Lipids Philippe Besnard,Jeffrey Christensen,Hélène Brignot,Arnaud Bernard,Patricia Passilly-Degraceet al. Scientific Reports, 2018, 8 (1), pp.6742. ⟨10.1038/s41598-018-24619-1⟩ Article dans une revue inserm-01792704v1
Acceptance of added fat to first complementary feeding purees: An exploration of fat type, feeding history and saliva composition Camille Schwartz,Jérôme Madrelle,Hélène Brignot,Julien J. Delarue,Gerard G. Cuvelieret al. Appetite, 2018, 131, pp.160-168. ⟨10.1016/j.appet.2018.08.007⟩ Article dans une revue hal-02621959v1
Protein expression in submandibular glands of young rats is modified by a high-fat/high-sugar maternal diet Martine Morzel,Hélène Brignot,Franck Menetrier,Géraldine Lucchi,Vincent Pailleet al. Archives of Oral Biology, 2018, 96, pp.87-95. ⟨10.1016/j.archoralbio.2018.08.021⟩ Article dans une revue hal-02629327v1
Chewing breads: impact on alpha-amylase secretion and oral digestion Marianne Joubert,Chantal Septier,Hélène Brignot,Christian Salles,Maud Panouilleet al. Food and Function, 2017, 8 (2), pp.607-614. ⟨10.1039/c6fo00963h⟩ Article dans une revue hal-01512143v1
The basal free fatty acid concentration in human saliva is related to salivary lipolytic activity Eric Neyraud,Stéphanie Cabaret,Hélène Brignot,Claire Chabanet,Hélène Labouréet al. Scientific Reports, 2017, 7 (1), pp.5969. ⟨10.1038/s41598-017-06418-2⟩ Article dans une revue hal-02142263v1
Differences in the Density of Fungiform Papillae and Composition of Saliva in Patients With Taste Disorders Compared to Healthy Controls Ute Walliczek-Dworschak,Franz Schöps,Gilles Feron,Hélène Brignot,Antje Hähneret al. Chemical Senses, 2017, 42 (8), pp.699 - 708. ⟨10.1093/chemse/bjx054⟩ Article dans une revue hal-01686513v1
Associations between food consumption patterns and saliva composition: Specificities of eating difficulties children Martine Morzel,Caroline Truntzer,Eric Neyraud,Hélène Brignot,Patrick Ducoroyet al. Physiology & behavior, 2017, 173, pp.116-123. ⟨10.1016/j.physbeh.2017.02.005⟩ Article dans une revue istex hal-01517239v1
Taste Bud Density and Composition of Saliva in Patients Suffering from Taste Disorders Compared to Healthy Individuals Franz Schoeps,,Antje Haehner,Hélène Brignot,Fabrice Neiers,Gilles Feronet al. Chemical Senses, 2016, 41 (7) Article dans une revue hal-01400218v1
Chewing bread: impact on alpha-amylase secretion and oral digestion Marianne Joubert,Chantal Septier,Hélène Brignot,Christian Salles,Maud Panouilleet al. Food and Function, 2016 Article dans une revue hal-01565151v1
Multi-omics profiling reveals that eating difficulties developed consecutively to artificial nutrition in the neonatal period are associated to specific saliva composition Martine Morzel,Eric Neyraud,Hélène Brignot,Patrick Ducoroy,Aline Jeanninet al. Journal of Proteomics, 2015, 128, pp.105-112. ⟨10.1016/j.jprot.2015.07.028⟩ Article dans une revue hal-01216253v2
Salivary markers of taste sensitivity to oleic acid: a combined proteomics and metabolomics approach Rana Mounayar,Martine Morzel,Hélène Brignot,Marie Tremblay-Franco,Cécile Canletet al. Metabolomics, 2014, 10 (4), pp.688-696. ⟨10.1007/s11306-013-0602-1⟩ Article dans une revue hal-01211077v1
Immunocytological detection of salivary mucins (MUC5B) on the mucosal pellicle lining human epithelial buccal cells Martine Morzel,Siying Tai,Hélène Brignot,Jeannine Lherminier Microscopy Research and Technique, 2014, 77 (6), pp.453-457. ⟨10.1002/jemt.22366⟩ Article dans une revue istex hal-02639958v1
Nutri-metabolomics applied to taste perception phenotype: Human subjects with high and low sensitivity to taste of fat differ in salivary response to oleic acid Rana Mounayar,Martine Morzel,Hélène Brignot,Marie Tremblay-Franco,Cécile Canletet al. OMICS, 2014, 18 (11), pp.666-672. ⟨10.1089/omi.2014.0108⟩ Article dans une revue hal-01211087v1

Communication dans un congrès (18)

La sensibilité à l'astringence en fonction de l'âge est-elle liée aux Protéines Riches en Proline (PRP) de la salive ? Hélène Brignot,Mei Wang,Chantal Septier,Francis Canon,Gilles Feron Journées Francophones de Nutrition (JFN), Nov 2022, Toulouse, France Communication dans un congrès hal-04041461v1
Proteomic characterization of the mucosal pellicle formed in vitro on a cellular model of oral epithelium Gianluigi Cabiddu,Pauline Maes,Hélène Brignot,Alessandra Olianas,Maria Teresa Sannaet al. Italian Proteomics Association and Hellenic Proteomics Society International Congress, Jun 2019, Catanzaro, Italy Communication dans un congrès hal-02788475v1
La salive peut-elle être utilisée comme un marqueur de l'état nutritionnel chez les seniors ? Hélène Brignot,Chantal Septier,Aurélie Laguerre,Gilles Feron Journées Francophones de Nutrition (JFN 2017), Dec 2017, Nantes, France. pp.320-321, ⟨10.1016/j.nupar.2018.09.187⟩ Communication dans un congrès hal-02735952v1
Infant fat acceptance: role of milk feeding practices and links with saliva composition Camille Schwartz,Jérôme Madrelle,Hélène Brignot,Julien Delarue,Gérard Cuvelieret al. Annual meeting of the Society for the Study of Ingestive Behavior (SSIB), Jul 2017, Montreal, Canada. 1 p Communication dans un congrès hal-01579297v1
Infant’s saliva lipolysis: relationships with age, milk and complementary feeding history Carole Tournier,Camille Schwartz,Hélène Brignot,Jérôme Madrelle,Sophie Nicklauset al. 5. international conference on food digestion (INFOGEST 2017), Apr 2017, Rennes, France. 1 p Communication dans un congrès hal-01579302v1
Children with eating disorders secondarily to artificial nutrition in the neonatal period have specific food preferences and saliva composition Martine Morzel,Eric Neyraud,Géraldine Lucchi,Hélène Brignot,Patrick Ducoroyet al. 49. annual meeting of the European society for paediatric gastroenterology, hepatology and nutrition, European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN). USA., May 2016, Athènes, Greece Communication dans un congrès hal-01512124v1
Activité lipolytique salivaire humaine : Mise en évidence et études préliminaires de caractérisation Hélène Brignot,Florian Le Joubioux,Francis Canon,Gilles Feron Journées francophones de nutrition (JFN), Nov 2016, Montpellier, France. 1 p Communication dans un congrès hal-01519322v1
Taste bud density and composition of saliva in patients suffering from taste disorders compared to healthy individuals Franz Schoeps,Antje Haehner,Hélène Brignot,Fabrice Neiers,Gilles Feronet al. 38. annual meeting - association for chemoreception sciences (AChemS), Apr 2016, Bonita Springs, United States Communication dans un congrès hal-01512212v1
L'expression protéique dans les glandes salivaires est impactée par un régime maternel de type Western-Diet chez le rat Hélène Brignot,Franck Ménétrier,Emma Gangloff,Vincent Paille,Patricia Parnetet al. Journées francophones de nutrition (JFN), Nov 2016, Montpellier, France. 1 p Communication dans un congrès hal-01519343v1
Relation entre composition salivaire, obésité et métabolisme lipidique postprandial chez l'Homme Cécile Vors,Jocelyne Drai,Laure Gabert,Martine Laville,Elisabeth Guichardet al. 12. Journées Francophones de Nutrition (JFN), Dec 2015, Montpellier, France Communication dans un congrès hal-01595299v1
Consequences of a high sugar/high fat maternal diet on protein expression in young rat salivary glands Martine Morzel,Hélène Brignot,Marie-Chantal Canivenc-Lavier,Vincent Paille,Patricia Parnetet al. 1. Congress of Physiology and Integrative Biology (CPBI), May 2015, Strasbourg, France. 92 p Communication dans un congrès hal-01249245v1
Multi-omics profiling reveals that eating difficulties developed consecutively to artificial nutrition in the neonatal period are associated to specific saliva composition Géraldine Lucchi,Martine Morzel,Eric Neyraud,Hélène Brignot,Patrick Ducoroyet al. Congrès français de Spectrométrie de Masse et d'Analyse Protéomique (SMAP 2015), 2015, Ajaccio, France Communication dans un congrès hal-01595504v1
Understanding food behaviour in child through his salivary composition. A prospective study on children expressing oral disorders Gilles Feron,Hélène Brignot,Patrick Ducoroy,Ségolène Gaillard,Aline Jeanninet al. Séminaire du projet européen HabEat, Mar 2014, Dijon, France Communication dans un congrès hal-01512178v1
Is saliva composition related to oral fat sensitivity or exposure? Rana Mounayar,Martine Morzel,Hélène Brignot,Cécile Canlet,Marie Tremblay-Francoet al. 10th Pangborn Symposium, Aug 2013, Rio de Janeiro, Brazil. 46 p Communication dans un congrès hal-00865843v1
Salivary markers and oral sensitivity to food: a prospective study on children expressing oral disorders Gilles Feron,Hélène Brignot,Patrick Ducoroy,Ségolène Gaillard,Aline Jeanninet al. 9.congrès international Goût nutrition santé, Apr 2014, Dijon, France Communication dans un congrès hal-01580657v1
Are metabolomics and proteomic salivary profiles related to human taste sensitivity to oleic acid? Rana Mounayar,Martine Morzel,Hélène Brignot,Marie Tremblay-Franco,Cécile Canletet al. 2. International congress of translational research in human nutrition "Integrative Approaches in Nutrition Research", Mar 2013, Clermont-Ferrand, France. 1 p Communication dans un congrès hal-01560688v1
Is saliva composition related to oral fat sensitivity or exposure? Rana Mounayar,Martine Morzel,Hélène Brignot,Cécile Canlet,Marie Tremblay-Francoet al. 10. Pangborn sensory science symposium, Aug 2013, Rio de Janeiro, Brazil. 46 p Communication dans un congrès hal-01267749v1
Adhesion of salivary mucins (MUC5B) to human buccal cells as affected by a taste solution Marion Zadoroznyj,Hélène Brignot,Marie-Annick Maire,Elodie Noirot,Christine Arnouldet al. Food Oral Processing: Physics, Physiology, and Psychology of Eating. Session 1: Interplays of food physics, oral physiology and sensory perception, Jul 2012, Beaune, France. 10 p Communication dans un congrès hal-02807091v1

Poster de conférence (7)

Exploring the role of oxidative stress in metallic taste during head and neck cancer treatment: a study of salivary markers and therapeutic interventions Hélène Brignot,Guillaume Buiret,Thierry Thomas-Danguin,Gilles Feron 7. International Conference on Food Oral Processing Physics, Physiology and Psychology of Eating, May 2025, Valencia, Spain. Poster de conférence hal-05097002v1
Mucin MUC1: a key protein in oral physiology and the molecular mechanisms of sensory perception of astringency Clément Nivet,Irma Čustović,Eric Lesniewska,Eric Bourillot,Hélène Brignotet al. 32. international congress of the european-chemoreception-research-organization (ECRO), Aug 2022, Berlin, Germany Poster de conférence hal-03772072v1
Development of a new in vitro model of oral mucosa to investigate a new hypothesis on the molecular origin of astringency Clément Nivet,Irma Čustović,Eric Lesniewska,Eric Bourillot,Hélène Brignotet al. 31. international congress of the european-chemoreception-research-organization (ECRO), Sep 2021, Cascais, Portugal. Poster de conférence hal-03772071v1
Salivary cathepsin L content differs between breastfed and formula-fed human infants Hélène Brignot,Laurine Chevalier,Camille Schwartz,Carole Tournier,Martine Morzel 5. International Conference on Food Oral Processing, Jul 2018, Nottingham, United Kingdom. , 1 p., 2018 Poster de conférence hal-02789167v1
Salivary redox status: a key parameter involved in the release and perception of sensory stimuli in human Gilles Feron,Hélène Brignot,Franz Schöps,Fabrice Neiers,Francis Canonet al. 5. International Conference on Food Oral Processing, Jul 2018, Nottingham, United Kingdom Poster de conférence hal-02916382v1
Consequences of a high sugar/high fat maternal diet on protein expression in young rat submandibular glands Martine Morzel,Géraldine Lucchi,Patrick Ducoroy,Hélène Brignot,Marie-Chantal Canivenc-Lavieret al. Congrès français de Spectrométrie de Masse et d'Analyse Protéomique (SMAP 2015), 2015, Ajaccio, Corse (France), France. , 2015 Poster de conférence hal-01580713v1
Markers of oral fat sensitivity; a combined proteomics and metabolomics approach Rana Mounayar,Martine Morzel,Hélène Brignot,Marie Tremblay-Franco,Cécile Canletet al. 1. International symposium on profiling, Sep 2013, Caparica, Portugal. 1 p., 2013 Poster de conférence hal-01519315v1

Proceedings/Recueil des communications (2)

Performance assessment of salivary screening in familial hypercholesterolemia in children M. Fricaudet,M. Di-Filippo,P. Moulin,P. Poinsot,C. Sageet al. Atherosclerosis, 331, pp.e183, 2021, Abstracts. E-Posters Topic: 3. DYSLIPIDEMIA AND RISK FACTORS / 3.05 Inherited dyslipidemias., ⟨10.1016/j.atherosclerosis.2021.06.558⟩ Proceedings/Recueil des communications hal-03349402v1
Is there a role for salivary detoxification enzymes in taste perception? Mathieu Schwartz,Hélène Brignot,Evelyne Chavanne,Gilles Feron,Thomas Hummelet al. 2021, Proceedings of the 16. Weurman flavour research symposium, ⟨10.5281/zenodo.5575005⟩ Proceedings/Recueil des communications hal-03686461v1

Pré-publication, Document de travail (2)

Evaluating the Etiology of Metallic Taste During Head and Neck Cancer Treatments: A Study of Facial and Glossopharyngeal Nerve Interactions Guillaume Buiret,Hélène Brignot,Chantal Septier,Gilles Feron,Thierry Thomas-Danguin 2024 Pré-publication, Document de travail hal-04823311v1
Astringency sensitivity to tannic acid: effect of ageing and salivary flow Mei Wang,Chantal Septier,Hélène Brignot,Christophe Martin,Francis Canonet al. 2021 Pré-publication, Document de travail (preprint/prepublication) hal-03197651v1

Rapport (1)

Rapport du groupe de travail sur les Missions Collectives (Conseil de Gestion du Département TRANSFORM, INRAE, 2020-2024) Hélène Brignot,Laurent Chaunier,Claire Coudrin,Guillaume Lubas,Marie-Emmanuelle Ollagnonet al. INRAE - Département Transform. 2025 Rapport hal-05235378v1