Michel Roux

Publications

Article dans une revue (48)

Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes Peter Vo,Denise Imai-Leonard,Benjamin Yang,Andrew Briere,Andy Shaoet al. BMC Genomics, 2025, 26 (1), pp.48. ⟨10.1186/s12864-025-11222-8⟩ Article dans une revue hal-05227499v1
Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated With Age-Related Corneal Dystrophies Andrew Briere,Peter Vo,Benjamin Yang,David Adams,Takanori Amanoet al. Investigative Ophthalmology & Visual Science, 2025, 66 (5), pp.7. ⟨10.1167/iovs.66.5.7⟩ Article dans une revue hal-05227476v1
Ocular Phenotyping of Knockout Mice Identifies Genes Associated With Late Adult Retinal Phenotypes Abraham Hang,Andy Shao,Michael Shea,Michel Roux,Denise Imai-Leonardet al. Investigative Ophthalmology & Visual Science, 2025, 66 (6), pp.64. ⟨10.1167/iovs.66.6.64⟩ Article dans une revue hal-05227463v1
Hyperglycemia and circadian disruption lead to retinal dysfunction in a stabilized colony of the fat sand rat Psammomys obesus Catherine Estay-Ahumada,Daniela Verra,Michel Roux,Fabiana Sassone,Marie-Paule Felder-Schmittbuhlet al. Biochimica et Biophysica Acta - Molecular Basis of Disease, 2024, 1870 (4), pp.167118. ⟨10.1016/j.bbadis.2024.167118⟩ Article dans une revue hal-04788767v1
Interruption of the visual cycle in a novel animal model induces progressive vision loss resembling Stargardts Disease Fabiana Sassone,Catherine Estay-Ahumada,Michel J. Roux,Dominique Ciocca,Paola Rossolilloet al. Scientific Reports, 2024, 14 (1), pp.30880. ⟨10.1038/s41598-024-81869-y⟩ Article dans une revue hal-04991247v1
Retinal dystrophins and the retinopathy of Duchenne muscular dystrophy Mirella Telles Salgueiro Barboni,Anneka Joachimsthaler,Michel Roux,Zoltán Zsolt Nagy,Dora Fix Venturaet al. Progress in Retinal and Eye Research, 2023, pp.101137. ⟨10.1016/j.preteyeres.2022.101137⟩ Article dans une revue hal-03863265v1
Polyglutamine-expanded ATXN7 alters a specific epigenetic signature underlying photoreceptor identity gene expression in SCA7 mouse retinopathy Anna Niewiadomska-Cimicka,Antoine Hache,Stéphanie Le Gras,Céline Keime,Tao Yeet al. Journal of Biomedical Science, 2022, 107, ⟨10.1186/s12929-022-00892-1⟩ Article dans une revue hal-03935562v1
SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2 Anna Niewiadomska-Cimicka,Frédéric Doussau,Jean-Baptiste Perot,Michel Roux,Celine Keimeet al. Journal of Neuroscience, 2021, 41 (22), pp.4910-4936. ⟨10.1523/JNEUROSCI.1882-20.2021⟩ Article dans une revue hal-03378998v1
Rescue of Defective Electroretinographic Responses in Dp71-Null Mice With AAV-Mediated Reexpression of Dp71 Mirella Telles Salgueiro Barboni,Cyrille Vaillend,Anneka Joachimsthaler,André Maurício Passos Liber,Hanen Khabouet al. Investigative Ophthalmology & Visual Science, 2020, 61 (2), pp.11. ⟨10.1167/iovs.61.2.11⟩ Article dans une revue hal-02520616v1
In vivo phenotypic and molecular characterization of retinal degeneration in mouse models of three ciliopathies Agnès Brun,Xiangxiang Yu,Cathy Obringer,Daniel Ajoy,Elodie Haseret al. Experimental Eye Research, 2019, 186, pp.107721. ⟨10.1016/j.exer.2019.107721⟩ Article dans une revue hal-02361666v1
Evidence for functional GABAA but not GABAC receptors on mouse cone photoreceptors Sercan Deniz,Eric Wersinger,Serge Picaud,Michel J Roux Visual Neuroscience, 2019, 36, pp.E005. ⟨10.1017/S0952523819000038⟩ Article dans une revue hal-02342212v1
Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts B Moore,B Leonard,L Sebbag,S Edwards,A Cooperet al. Communications Biology, 2019, 2, ⟨10.1038/s42003-019-0349-y⟩ Article dans une revue hal-03676428v1
High frequency stimulation of normal and blind mouse retinas using TiO2 nanotubes Carole Ronzani,Thomas Cottineau,Irene Gonzalez-Valls,Valérie Keller,Serge Picaudet al. Advanced Functional Materials, 2018, 28 (50), pp.1804639. ⟨10.1002/adfm.201804639⟩ Article dans une revue hal-02180072v1
Identification of genes required for eye development by high-throughput screening of mouse knockouts Bret A Moore,Brian Leonard,Lionel Sebbag,Sydney Edwards,Ann Cooperet al. Communications Biology, 2018, 1 (1), ⟨10.1038/s42003-018-0226-0⟩ Article dans une revue hal-02342264v1
A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice Bret A Moore,Michel Roux,Lionel Sebbag,Ann Cooper,Sydney G Edwardset al. Investigative Ophthalmology & Visual Science, 2018, 59 (6), pp.2252. ⟨10.1167/iovs.17-23513⟩ Article dans une revue hal-02361529v1
Panton-Valentine Leucocidin Proves Direct Neuronal Targeting and Its Early Neuronal and Glial Impacts a Rabbit Retinal Explant Model Xuanli Liu,Michel J. Roux,Serge Picaud,Daniel Keller,Arnaud Saueret al. Toxins, 2018, 10 (11), pp.455. ⟨10.3390/toxins10110455⟩ Article dans une revue hal-01953905v1
Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors Cesare Orlandi,Yoshihiro Omori,Yuchen Wang,Yan Cao,Akiko Uenoet al. Cell Reports, 2018, 25 (1), pp.130 - 145. ⟨10.1016/j.celrep.2018.08.068⟩ Article dans une revue hal-02361463v1
Panton–Valentine Leukocidin Colocalizes with Retinal Ganglion and Amacrine Cells and Activates Glial Reactions and Microglial Apoptosis Xuanli Liu,Pauline Heitz,Michel Roux,Daniel Keller,Tristan Bourcieret al. Scientific Reports, 2018, 8, pp.2953. ⟨10.1038/s41598-018-20590-z⟩ Article dans une revue hal-02359626v1
Asymmetrical Functional Deficits of ON and OFF Retinal Processing in the mdx 3Cv Mouse Model of Duchenne Muscular Dystrophy Tina I. Tsai,Mirella Telles Salgueiro Barboni,Balázs Vince Nagy,Michel Roux,Alvaro Rendonet al. Investigative Ophthalmology & Visual Science, 2016, 57 (13), pp.5788. ⟨10.1167/iovs.16-19432⟩ Article dans une revue hal-03706658v1
Comparing the Bbs10 complete knockout phenotype with a specific renal epithelial knockout one highlights the link between renal defects and systemic inactivation in mice Noëlle Cognard,Maria Scerbo,Cathy Obringer,Xiangxiang Yu,Fanny Costaet al. Cilia, 2015, 4 (1), pp.10. ⟨10.1186/s13630-015-0019-8⟩ Article dans une revue hal-04788664v1
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics Martin Hrabě de Angelis,George Nicholson,Mohammed Selloum,Jacqueline White,Hugh Morganet al. Nature Genetics, 2015, 47 (9), pp.969-978. ⟨10.1038/ng.3360⟩ Article dans une revue hal-04673653v1
Deletion of the App-Runx1 region in mice models human partial monosomy 21 Thomas Arbogast,Matthieu Raveau,Claire Chevalier,Valérie Nalesso,Doulaye Dembeleet al. Disease Models & Mechanisms, 2015, 8 (6), pp.623-634. ⟨10.1242/dmm.017814⟩ Article dans une revue hal-04788629v1
Elk3 Deficiency Causes Transient Impairment in Post-Natal Retinal Vascular Development and Formation of Tortuous Arteries in Adult Murine Retinae Christine Weinl,Christine Wasylyk,Marina Garcia Garrido,Vithiyanjali Sothilingam,Susanne Becket al. PLoS ONE, 2014, 9 (9), pp.e107048. ⟨10.1371/journal.pone.0107048⟩ Article dans une revue hal-04788622v1
Hyperactivation of Alk induces neonatal lethality in knock-in AlkF1178L mice. Lucille Lopez-Delisle,Cécile Pierre-Eugène,Evelyne Bloch-Gallego,Marie-Christine Birling,Jean-Loup Dubandet al. Oncotarget, 2014, 5 (9), pp.2703-13. ⟨10.18632/oncotarget.1882⟩ Article dans une revue inserm-01328110v1
Proteomic Survey Reveals Altered Energetic Patterns and Metabolic Failure Prior to Retinal Degeneration Ana Griciuc,Michel J Roux,Juliane Merl,Angela Giangrande,Stefanie M Haucket al. Journal of Neuroscience, 2014, 34 (8), pp.2797-2812. ⟨10.1523/JNEUROSCI.2982-13.2014⟩ Article dans une revue hal-03447891v1
A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains. Michelle Simon,Simon Greenaway,Jacqueline White,Helmut Fuchs,Valérie Gailus-Durneret al. Genome Biology, 2013, 14 (7), pp.R82. ⟨10.1186/gb-2013-14-7-r82⟩ Article dans une revue inserm-00874969v1
Drosophila fatty acid transport protein regulates rhodopsin-1 metabolism and is required for photoreceptor neuron survival Pierre Dourlen,Benjamin Bertin,Gilles Chatelain,Marion Robin,Francesco Napoletanoet al. PLoS Genetics, 2012, 8 (7), pp.e1002833. ⟨10.1371/journal.pgen.1002833⟩ Article dans une revue hal-04211805v1
Reevaluation of Dystrophin Localization in the Mouse Retina E. Wersinger,Agnès Bordais,Yannick Schwab,Abdoulaye Sene,Romain Bénardet al. Investigative Ophthalmology & Visual Science, 2011, 52 (11), pp.7901. ⟨10.1167/iovs.11-7519⟩ Article dans une revue hal-04788572v1
beta-Endorphin expression in the mouse retina Shannon K. Gallagher,Paul Witkovsky,Michel Roux,Malcolm J. Low,Veronica Otero-Corchonet al. Journal of Comparative Neurology, 2010, 518 (15), pp.3130-3148. ⟨10.1002/cne.22387⟩ Article dans une revue hal-04009065v1
A postsynaptic signaling pathway that may account for the cognitive defect due to IL1RAPL1 mutation Alice Pavlowsky,Antonella Gianfelice,Marta Pallotto,Alice Zanchi,Hugo Varaet al. Current Biology, 2010, 20 (2), pp.103-115. ⟨10.1016/j.cub.2009.12.030⟩ Article dans une revue hal-04087157v1
ANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines C Ayoub,Christine Wasylyk,Y Li,E Thomas,L Marisaet al. British Journal of Cancer, 2010, 103 (5), pp.715-726. ⟨10.1038/sj.bjc.6605823⟩ Article dans une revue hal-04009054v1
Retinoic Acid Receptor (RAR)-α Is Not Critically Required for Mediating Retinoic Acid Effects in the Developing Mouse Retina Laura Cammas,Frédéric Trensz,Abdeljalil Jellali,Norbert Ghyselinck,Michel J Rouxet al. Investigative Ophthalmology & Visual Science, 2010, 51 (6), pp.3281. ⟨10.1167/iovs.09-3769⟩ Article dans une revue hal-04788532v1
Inactivation of VCP/ter94 Suppresses Retinal Pathology Caused by Misfolded Rhodopsin in Drosophila Ana Griciuc,Liviu Aron,Michel J Roux,Rüdiger Klein,Angela Giangrandeet al. PLoS Genetics, 2010, 6 (8), pp.e1001075. ⟨10.1371/journal.pgen.1001075⟩ Article dans une revue hal-03447945v1
Functional implication of Dp71 in osmoregulation and vascular permeability of the retina Abdoulaye Sene,Ramin Tadayoni,Thomas Pannicke,Antje Wurm,Brahim El Mathariet al. PLoS ONE, 2009, 4 (10), ⟨10.1371/journal.pone.0007329⟩ Article dans une revue hal-04118000v1
Kir4.1 and AQP4 associate with Dp71- and utrophin-DAPs complexes in specific and defined microdomains of Müller retinal glial cell membrane. Patrice E. Fort,Abdoulaye Sene,Thomas Pannicke,Michel J. Roux,Valérie Forsteret al. Glia, 2008, 56 (6), pp.597-610. ⟨10.1002/glia.20633⟩ Article dans une revue istex inserm-00265573v1
High-resolution imaging of retinal cells in the living eye M Paques,M Simonutti,Michel J Roux,C Bellman,F Lacombeet al. Eye, 2007, 21 (S1), pp.S18-S20. ⟨10.1038/sj.eye.6702882⟩ Article dans une revue hal-04788512v1
Glycine receptors in a population of adult mammalian cones E. Balse,Luc-Henri Tessier,V. Forster,M.J. Roux,José-Alain Sahelet al. The Journal of Physiology, 2006, 571 (Pt 2), pp.391-401 Article dans une revue hal-00143253v1
Physiological maturation of photoreceptors depends on the voltage-gated sodium channel NaV1.6 (Scn8a) Patrice D. Côté,Yves de Repentigny,Stuart G. Coupland,Yannick Schwab,Michel Rouxet al. Journal of Neuroscience, 2005, 25 (20), pp.5046-5050. ⟨10.1523/JNEUROSCI.4692-04.2005⟩ Article dans une revue hal-04135456v1
Rhodopsin maturation defects induce photoreceptor death by apoptosis: a fly model for RhodopsinPro23His human retinitis pigmentosa. Anne Galy,Michel J. Roux,José-Alain Sahel,Thierry Léveillard,Angela Giangrande Human Molecular Genetics, 2005, 14 (17), pp.2547-57. ⟨10.1093/hmg/ddi258⟩ Article dans une revue istex hal-00187543v1
Why glycine transporters have different stoichiometries. Stéphane Supplisson,Michel J Roux FEBS Letters, 2002, 529 (1), pp.93-101 Article dans une revue hal-00145152v1
Why glycine transporters have different stoichiometries Stéphane Supplisson,Michel J Roux FEBS Letters, 2002, 529 (1), pp.93-101. ⟨10.1016/s0014-5793(02)03251-9⟩ Article dans une revue hal-04788404v1
The Glial and the Neuronal Glycine Transporters Differ in Their Reactivity to Sulfhydryl Reagents Michel J Roux,Rodrigo Martı́nez-Maza,Anne Le Goff,Beatriz López-Corcuera,Carmen Aragónet al. Journal of Biological Chemistry, 2001, 276 (21), pp.17699-17705. ⟨10.1074/jbc.M009196200⟩ Article dans une revue hal-04788396v1
The glial and the neuronal glycine transporters differ in their reactivity to sulfhydryl reagents. Michel J. Roux,Rodrigo Martinez-Maza,Anne Le Goff,Beatriz Lopez-Corcuera,Carmen Aragonet al. Journal of Biological Chemistry, 2001, 276 (21), pp.17699-705. ⟨10.1074/jbc.M009196200⟩ Article dans une revue hal-00140067v1
Neuronal and glial glycine transporters have different stoichiometries. Michel J. Roux,Stéphane Supplisson Neuron, 2000, 25 (2), pp.373-83 Article dans une revue hal-00140070v1
Neuronal and Glial Glycine Transporters Have Different Stoichiometries Michel J Roux,Stéphane Supplisson Neuron, 2000, 25 (2), pp.373-383. ⟨10.1016/s0896-6273(00)80901-0⟩ Article dans une revue hal-04788394v1
Differential properties of two stably expressed brain-specific glycine transporters. B. López-Corcuera,R. Martínez-Maza,E. Núñez,M. Roux,S. Supplissonet al. Journal of Neurochemistry, 1998, 71 (5), pp.2211-9. ⟨10.1046/j.1471-4159.1998.71052211.x⟩ Article dans une revue hal-00145600v1
A Xenopus oocyte β subunit: Evidence for a role in the assembly/expression of voltage-gated calcium channels that is separate from its role as a regulatory subunit Erwin Tareilus,Michel Roux,Ning Qin,Riccardo Olcese,Jianming Zhouet al. Proceedings of the National Academy of Sciences of the United States of America, 1997, 94 (5), pp.1703-1708. ⟨10.1073/pnas.94.5.1703⟩ Article dans une revue hal-04788267v1
External barium influences the gating charge movement of Shaker potassium channels R.S. Hurst,M.J. Roux,L. Toro,E. Stefani Biophysical Journal, 1997, 72 (1), pp.77-84. ⟨10.1016/S0006-3495(97)78648-X⟩ Article dans une revue hal-04788149v1

Pré-publication, Document de travail (1)

Abca4 inhibition in a cone-rich rodent leads to Stargardt Disease type 1-like retinal degeneration Fabiana Sassone,Michel J. Roux,Dominique Ciocca,Paola Rossolillo,Marie-Christine Birlinget al. 2023 Pré-publication, Document de travail hal-04284705v1

Communication dans un congrès (1)

High frequency stimulations of wild type and blind mouse retinas using titanium dioxide nanotubes as artificial photoreceptors Michel J Roux,Thomas Cottineau,Valérie Keller,Nicolas Keller,Carole Ronzani 2016 ARVO Annual Meeting, May 1-5 2016, Seattle, Wash., May 2016, Seattle, United States Communication dans un congrès hal-04427655v1