Adeline SIVIGNON

Publications

Article dans une revue (29)

Biochemical characterization of the Escherichia coli surfaceome: a focus on type I fimbriae and flagella Devon Kavanaugh,Adeline Sivignon,Yannick Rossez,Zina Chouit,Christophe Chambonet al. Frontiers in Microbiology, 2025, 16, pp.1507286. ⟨10.3389/fmicb.2025.1507286⟩ Article dans une revue hal-04958057v1
Development of a combination of probiotics and plant extracts targeting adherent-invasive Escherichia coli associated with Crohn’s disease F. de Clercq,N. Boisseau,C. Leclaire,J. Denizot,S. Holowaczet al. Beneficial Microbes, 2025, pp.1-17. ⟨10.1163/18762891-bja00095⟩ Article dans une revue hal-05319060v1
ChiA: a major player in the virulence of Crohn’s disease-associated adherent and invasive Escherichia coli (AIEC) Margot Fargeas,Frederic Faure,Clara Douadi,Caroline Chevarin,Aurélien Bireret al. Gut microbes, 2024, 16 (1), ⟨10.1080/19490976.2024.2412667⟩ Article dans une revue (data paper) hal-04809777v1
An adherent-invasive Escherichia coli -colonized mouse model to evaluate microbiota-targeting strategies in Crohn's disease Adeline Sivignon,Mélissa Chervy,Caroline Chevarin,Elia Ragot,Elisabeth Billardet al. Disease Models & Mechanisms, 2022, 15 (10), pp.dmm049707. ⟨10.1242/dmm.049707⟩ Article dans une revue hal-03907399v1
Epigenetic master regulators HDAC1 and HDAC5 control pathobiont Enterobacteria colonization in ileal mucosa of Crohn’s disease patients Mélissa Chervy,Adeline Sivignon,Flavie Dambrine,Anthony Buisson,Pierre Sauvanetet al. Gut microbes, 2022, 14 (1), pp.1-13. ⟨10.1080/19490976.2022.2127444⟩ Article dans une revue hal-03881385v1
Beneficial Effects of Linseed Supplementation on Gut Mucosa-Associated Microbiota in a Physically Active Mouse Model of Crohn's Disease Claire Plissonneau,Adeline Sivignon,Benoit Chassaing,Frédéric Capel,Vincent Martinet al. International Journal of Molecular Sciences, 2022, 23 (11), pp.1-21. ⟨10.3390/ijms23115891⟩ Article dans une revue hal-03677749v1
Tripartite relationship between gut microbiota, intestinal mucus and fibers: towards preventive strategies against enteric infections Thomas Sauvaitre,Lucie Etienne-Mesmin,Adeline Sivignon,Pascale Mosoni,Christophe Courtinet al. FEMS Microbiology Reviews, 2021, 45 (2), pp.1-36. ⟨10.1093/femsre/fuaa052⟩ Article dans une revue (article de synthèse) hal-02913569v1
Ulcerative Colitis-associated E. coli pathobionts potentiate colitis in susceptible hosts Hyungjun Yang,Hengameh Chloé Mirsepasi-Lauridsen,Carsten Struve,Joannie M Allaire,Adeline Sivignonet al. Journal of Immunology, 2020, 12 (1), pp.1-20. ⟨10.1080/19490976.2020.1847976⟩ Article dans une revue hal-03003143v1
Methyl-donor supplementation prevents intestinal colonization by Adherent-invasive E. coli in a mouse model of crohn's disease Elodie Gimier,Mélissa Chervy,Allison Agus,Adeline Sivignon,Elisabeth Billardet al. Scientific Reports, 2020, 10, pp.12922. ⟨10.1038/s41598-020-69472-3⟩ Article dans une revue hal-02917129v1
Heptylmannose-functionalized cellulose for the binding and specific detection of pathogenic E. coli Madeleine Cauwel,Adeline Sivignon,Clarisse Bridot,Medy Nongbe,David Deniaudet al. Chemical Communications, 2019, 55 (68), pp.10158-10161. ⟨10.1039/c9cc05545b⟩ Article dans une revue hal-02360573v1
Oligomannose-Rich Membranes of Dying Intestinal Epithelial Cells Promote Host Colonization by Adherent-Invasive E. coli Tetiana Dumych,Nao Yamakawa,Adeline Sivignon,Estelle Garénaux,Stefania Robakiewiczet al. Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.00742⟩ Article dans une revue hal-01796957v1
Anti-infectious properties of the probiotic Saccharomyces cerevisiae CNCM I-3856 on enterotoxigenic E. coli (ETEC) strain H10407 S. Denis,T Tsilia,N. Ballet,P. Vandekerckove,T. van de Wieleet al. Applied Microbiology and Biotechnology, 2018, 102 (14), pp.6175-6189. ⟨10.1007/s00253-018-9053-y⟩ Article dans une revue hal-01809200v1
The potential of FimH as a novel therapeutic target for the treatment of Crohn’s disease Adeline Sivignon,Julie Bouckaert,Julien Bernard,Sebastien G. Gouin,Nicolas Barnich Expert Opinion on Therapeutic Targets, 2017, 21 (9), pp.837 - 847. ⟨10.1080/14728222.2017.1363184⟩ Article dans une revue (article de synthèse) hal-01633566v1
Foodborne enterotoxigenic Escherichia coli: from gut pathogenesis to new preventive strategies involving probiotics Charlene Roussel,Adeline Sivignon,Tom van de Wiele,Stephanie Blanquet-Diot Future Microbiology, 2017, 12 (1), pp.73-93. ⟨10.2217/fmb-2016-0101⟩ Article dans une revue (article de synthèse) hal-01600225v1
Bacteriophages targeting adherent invasive Escherichia coli strains as a promising new treatment for Crohn's disease Matthieu Galtier,Luisa de Sordi,Adeline Sivignon,Amélie de Vallée,Christel Neutet al. Journal of Crohn's and Colitis, 2017, Advance publication online (7), pp.840-847. ⟨10.1093/ecco-jcc/jjw224⟩ Article dans une revue pasteur-01538942v1
The Antiadhesive Strategy in Crohn′s Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut Dimitri Alvarez-Dorta,Adeline Sivignon,Thibaut Chalopin,Tetiana Dumych,Goedele Rooset al. ChemBioChem, 2016, 17 (10), pp.936-952. ⟨10.1002/cbic.201600018⟩ Article dans une revue istex hal-02077036v1
Second generation of thiazolylmannosides, FimH antagonists for E. coli-induced Crohn's disease T. Chalopin,D. Alvarez Dorta,Adeline Sivignon,M. Caudan,T. Dumychet al. Organic & Biomolecular Chemistry, 2016, 14 (16), pp.3913-3925. ⟨10.1039/c6ob00424e⟩ Article dans une revue hal-02077029v1
Differentiation of Crohn’s Disease-Associated Isolates from Other Pathogenic Escherichia coli by Fimbrial Adhesion under Shear Force Sabine Szunerits,Oleksandr Zagorodko,Virginie Cogez,Tetiana Dumych,Thibaut Chalopinet al. Biology, 2016, 5 (2), ⟨10.3390/biology5020014⟩ Article dans une revue hal-01741244v1
A library of heptyl mannose-functionalized copolymers with distinct compositions, microstructures and neighboring non-sugar motifs as potent antiadhesives of type 1 piliated E. coli Xibo Yan,Adeline Sivignon,Nicolas Barnich,Sébastien G Gouin,Julie Bouckaertet al. Polymer Chemistry, 2016, 7 (15), pp.2674-2683. ⟨10.1039/c6py00118a⟩ Article dans une revue hal-01396465v1
Development of Heptylmannoside-Based Glycoconjugate Antiadhesive Compounds against Adherent-Invasive Escherichia coli Bacteria Associated with Crohn's Disease Adeline Sivignon,Xibo Yan,Dimitri Alvarez Dorta,Richard Bonnet,Julie Bouckaertet al. mBio, 2015, 6 (6), pp.e01298-15. ⟨10.1128/mBio.01298-15⟩ Article dans une revue hal-01265411v1
Brilliant glyconanocapsules for trapping of bacteria Xibo Yan,Adeline Sivignon,Pierre Alcouffe,Béatrice Burdin,Sabine Favre-Bonteet al. Chemical Communications, 2015, 51 (67), pp.13193-13196. ⟨10.1039/c5cc04653j⟩ Article dans une revue hal-01221578v1
Inhibition profiles of mono- and polyvalent FimH antagonists against 10 different Escherichia coli strains T. Chalopin,Y. Brissonnet,Adeline Sivignon,David Deniaud,L. Cremetet al. Organic & Biomolecular Chemistry, 2015, 13 (46), pp.11369 - 11375. ⟨10.1039/c5ob01581b⟩ Article dans une revue hal-01931394v1
Glycopolymers as Antiadhesives of E. coil Strains Inducing Inflammatory Bowel Diseases Xibo Yan,Adeline Sivignon,Nao Yamakawa,Agnès Crepet,Christophe Traveletet al. Biomacromolecules, 2015, 16 (6), pp.1827-1836. ⟨10.1021/acs.biomac.5b00413⟩ Article dans une revue hal-01174249v1
Saccharomyces cerevisiae CNCM I-3856 Prevents Colitis Induced by AIEC Bacteria in the Transgenic Mouse Model Mimicking Crohnʼs Disease Adeline Sivignon,Amélie de Vallée,Nicolas Barnich,Jérémy Denizot,Claude Darchaet al. Inflammatory Bowel Diseases, 2015, 21 (2), pp.276 - 286. ⟨10.1097/MIB.0000000000000280⟩ Article dans une revue hal-01928174v1
In Memoriam, Arlette Darfeuille-Michaud, PhD Jennifer Raisch,Adeline Sivignon,Benoit Chassaing,Pierre Lapaquette,Sylvie Miquelet al. Gastroenterology, 2014, 147 (5), pp.943-944. ⟨10.1136/gutjnl-2014-308182⟩ Article dans une revue hal-01951060v1
Thiazolylaminomannosides As Potent Antiadhesives of Type 1 Piliated Escherichia coli Isolated from Crohn’s Disease Patients Sami Brument,Adeline Sivignon,Tetiana Dumych,Nicolas Moreau,Goedele Rooset al. Journal of Medicinal Chemistry, 2013, 56 (13), pp.5395 - 5406. ⟨10.1021/jm400723n⟩ Article dans une revue hal-01931359v1
Adherent-Invasive Escherichia coli Induce Claudin-2 Expression and Barrier Defect in CEABAC10 Mice and Crohnʼs Disease Patients Jérémy Denizot,Adeline Sivignon,Frederick Barreau,Claude Darcha,Carlos H.F. Chanet al. Inflammatory Bowel Diseases, 2012, 18 (2), pp.294 - 304. ⟨10.1002/ibd.21787⟩ Article dans une revue hal-01928192v1
Cyclomodulins in Urosepsis Strains of Escherichia coli Didier Dubois,J. Delmas,A. Cady,F. Robin,Adeline Sivignonet al. Journal of Clinical Microbiology, 2010, 48 (6), pp.2122 - 2129. ⟨10.1128/JCM.02365-09⟩ Article dans une revue hal-01931345v1
Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM Frédéric A Carvalho,Nicolas Barnich,Adeline Sivignon,Claude Darcha,Carlos H F Chanet al. Journal of Experimental Medicine, 2009, 206 (10), pp.2179 - 2189. ⟨10.1084/jem.20090741⟩ Article dans une revue hal-01931313v1

Communication dans un congrès (14)

Biochemical characterization of the Escherichia coli surfaceome: a focus on type I fimbriae and flagella Devon Kavanaugh,Adeline Sivignon,Yannick Rossez,Zina Chouit,Chirstophe Chambonet al. 21èmes Rencontres des Microbiologies du Pôle Clermontois, Apr 2025, Clermont -Ferrand, France Communication dans un congrès hal-05496598v1
Élaboration d'une formulation combinant souches bactériennes et extraits végétaux ciblant les souches « Adherent Invasive Escherichia coli » (AIEC) associées à la maladie de Crohn Fanny de Clercq,Charlotte Leclaire,Jérémy Denizot,Sophie Holowacz,Nathalie Boisseauet al. Journée Nutrition & Microbiote (De la prévention à la thérapie), Atlanpole Biothérapies, Nov 2024, Nantes, France Communication dans un congrès hal-04959285v1
Cooperation between symbiotic bacteria and pathobionts in the intestine? Adeline Sivignon Final Symposium of the Microbiota cross-cutting program of Inserm, Inserm (I3M and PMN), Oct 2024, Paris necker, France Communication dans un congrès hal-04959251v1
Presentation of endochitinase ChiA, a virulence factor involved in the pathogenecity of adherent and invasive Escherichia coli associated with Crohn’s Disease Margot Fargeas,Frédéric Faure,Clara Douadi,Caroline Chevarin,Adeline Sivignonet al. G-REEMI, Oct 2024, Clermont-Ferrand, France Communication dans un congrès hal-04974385v1
ChiA, a major player in the pathogenicity of adherent and invasive E. coli bacteria (AIEC) associated with Crohn's disease. Margot Fargeas,Frédéric Faure,Clara Douadi,Caroline Chevarin,Adeline Sivignonet al. Journées scientifiques de l'école doctorale SVSAE (Sciences de la Vie, de la Santé, de l'Agronomie et de l'Environnement), Jun 2024, Clermont-Ferrand, France Communication dans un congrès hal-04974353v1
Élaboration d'une formulation combinant souches bactériennes et extraits végétaux ciblant les souches « Adherent-Invasive Escherichia coli » (AIEC) associées à la maladie de Crohn Fanny de Clercq,Charlotte Leclaire,Sophie Holowacz,Nathalie Boisseau,Nicolas Barnichet al. Rencontre des microbiologistes clermontois, Fédération des Systèmes Microbiens (SYSMIC), Apr 2024, Clermont- Ferrand, France Communication dans un congrès hal-04959971v1
Développement d'outils prophylactiques ou thérapeutiques ciblant les Escherichia coli adhérents et invasifs dans le contexte de la Maladie de Crohn Adeline Sivignon Colloque Recherche IUT, IUT Aubière, Jul 2024, Aubière / Clermont-Ferrand, France Communication dans un congrès hal-04959269v1
Towards a better description of the interactions of food-borne pathogen Enterotoxigenic Escherichia coli with intestinal mucus and human microbiome. Thomas Sauvaitre,Josefien van Landuyt,Claude Durif,Charlène Roussel,Adeline Sivignonet al. 13th International Gut Microbiology Symposium 2023, University of Aberdeen, Jun 2023, Aberdeen (Scotland), United Kingdom Communication dans un congrès hal-04215030v1
Élaboration d'une formulation combinant souches probiotiques et extraits végétaux ciblant les souches « Adherent-Invasive Escherichia coli » (AIEC) associées à la maladie de Crohn Fanny de Clercq,Nicolas Barnich,Sophie Holowacz,Nathalie Boisseau,Adeline Sivignon SFM : 18ème congrès de la Société Française de Microbiologie, SFM, Oct 2023, Rennes, France Communication dans un congrès hal-04959950v1
Interactions between intestinal microbiota, mucus layer and dietary fiber: towards preventive strategies to mitigate virulence of food-borne pathogen Enterotoxigenic Escherichia coli. Thomas Sauvaitre,Josefien van Landuyt,Claude Durif,Charlène Roussel,Adeline Sivignonet al. 12th Probiobiotics, Prebiotics and New Foods, Sep 2023, Rome, Italy Communication dans un congrès hal-04659433v1
Mucus-bacteria interactions: impact on Enterotoxigenic Escherichia coli virulence and interplay with the human gut microbiome Thomas Sauvaitre,Josefien van Landuyt,Claude Durif,Charlène Roussel,Adeline Sivignonet al. 10th FEMS Congress of European Microbiologists, FEMS, Jul 2023, Hambourg (Neversdorf), Germany Communication dans un congrès hal-04214669v1
“pVill-hCC6”: A NEW MOUSE MODEL MIMICKING ILEAL COLONIZATION BY AIEC BACTERIA TO EVALUATE MICROBIOTA-TARGETING STRATEGIES IN CROHN’S DISEASE Adeline Sivignon,Mélissa Chervy,Caroline Chevarin,Elisabeth Billard,Jérémy Denizotet al. Digestive Disease Week 2022, DDW, May 2022, San diego (Californie), United States Communication dans un congrès hal-04959953v1
From mechanisms of bacterial binding to glycomimics Tetiana Dumych,Adeline Sivignon,Antonio Bongiovanni,Nao Yamakawa,Fabrice Brayet al. GLYCOALP, Jun 2019, Genoble, France Communication dans un congrès hal-02196745v1
Physiochemical tuning of potent escherichia coli anti-adhesives by microencapsulation and methylene homologation Dimitri Alvarez-Dorta,Thibaut Chalopin,Adeline Sivignon,Jerome de Ruyck,Tetiana I. Dumychet al. 52. International Conference on Medicinal Chemistry (RICT) of the French-Medicinal-Chemistry-Society (SCT) - Interfacing Chemical Biology and Drug Discovery, Jul 2016, Caen, France. pp.13, ⟨10.1002/cmdc.201700061⟩ Communication dans un congrès hal-01607981v1

Poster de conférence (13)

Interaction between Chitinase 3-like 1 (CHI3L1) and bacterial protein ChiA : a decisive step for Crohn’s disease-associated adherent and invasive E. coli to enter within human macrophages. Margot Fargeas,Frédéric Faure,Caroline Chevarin,Clara Douadi,Adeline Sivignonet al. Digestive Disease Week (DDW), May 2024, Washington, United States Poster de conférence hal-04974337v1
Interaction between Chitinase 3-like 1 (CHI3L1) and bacterial protein ChiA : a decisive step for Crohn’s disease-associated adherent and invasive E. coli to enter within human macrophages. Margot Fargeas,Frédéric Faure,Clara Douadi,Adeline Sivignon,Caroline Chevarinet al. European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Apr 2024, Barcenola, Spain Poster de conférence hal-04974301v1
Development of a combination of probiotics and plant extracts targeting Adherent-Invasive Escherichia coli associated with Crohn's disease Fanny de Clercq,Charlotte Leclaire,Jérémy Denizot,Sophie Holowacz,Nathalie Boisseauet al. Final symposium of the Microbiota cross-cutting program of Inserm, Oct 2024, Paris necker, France Poster de conférence hal-04959963v1
Biochemical characterization of the Escherichia coli surfaceome: a focus on type I fimbriae and flagella Devon Kavanaugh,Adeline Sivignon,Yannick Rossez,Zina Chouit,Christophe Chambonet al. PTM (Projet Transverse Inserm- Microbiote), Oct 2024, Paris, France. Poster de conférence hal-04989578v1
EPIGENETIC MASTER REGULATORS HDAC1 AND HDAC5 CONTROL PATHOBIONT ENTEROBACTERIA COLONIZATION IN ILEAL MUCOSA IN CROHN’S DISEASE PATIENTS Mélissa Chervy,Adeline Sivignon,Nicolas Barnich,Jérémy Denizot G-RREMI 2022, Sep 2022, Lyon, France Poster de conférence hal-04977447v1
EPIGENETIC MASTER REGULATORS HDAC1 AND HDAC5 CONTROL PATHOBIONT ENTEROBACTERIA COLONIZATION IN ILEAL MUCOSA IN CROHN'S DISEASE PATIENTS Mélissa Chervy,Adeline Sivignon,Matthieu Allez,Lionel Le Bourhis,Nicolas Barnichet al. Digestive Disease Week 2022, May 2022, San Diego (California), United States Poster de conférence hal-04977395v1
EPIGENETIC MASTER REGULATORS HDAC1 AND HDAC5 CONTROL PATHOBIONT ENTEROBACTERIA COLONIZATION IN ILEAL MUCOSA IN CROHN’S DISEASE PATIENTS Mélissa Chervy,Adeline Sivignon,Nicolas Barnich,Jérémy Denizot EMBO Workshow Pathogen Immunity and Signaling, Apr 2022, Saint-Malo (35400), France Poster de conférence hal-04977437v1
Beneficial Effects of Linseed Diet-supplementation and Spontaneous Physical activity on Inflammation and the Mucosa-Associated Microbiota. Claire Plissonneau,Adeline Sivignon,Benoit Chassaing,Frédéric Capel,Martin Vincentet al. UEGW, Oct 2021, Virtual, France Poster de conférence hal-03462036v1
Use of a fiber-based strategy to prevent enterotoxigenic Escherichia coli infections: in vitro investigation on their antagonistic effects Thomas Sauvaitre,Charlene Roussel,Adeline Sivignon,Sandrine Chalancon,Claude Durifet al. 12. International Symposium on Gut Microbiology, Oct 2021, En ligne, France. 2021 Poster de conférence hal-03395516v1
Novel approach to bind and specifically detect FimH-expressing E. coli using heptylmannose-functionalized cellulose Adeline Sivignon,Antoine Chaprenet,François-Xavier Felpin,Julie Bouckaert,Nicolas Barnich DDW 2020, May 2020, CHICAGO, United States Poster de conférence hal-03043378v1
Novel approach to bind and specifically detect FIMH-expressing E. coli using heptylmannose-functionalized cellulose in the context of Crohn's disease Adeline Sivignon,Antoine Chaprenet,Francois-Xavier Felpin,Julie Bouckaert,Sebastien G. Gouinet al. UEGW 2020, Oct 2020, AMSTERDAM, France Poster de conférence hal-03046355v1
Novel approach to bind and specifically detect FimH-expressing E. coli using heptylmannose-functionalized cellulose Adeline Sivignon,Madeleine Cauwel,David Deniaud,Benoit Roubinet,Ludovic Landemarreet al. 15e congrès national de la SFM, Sep 2019, Paris, France Poster de conférence hal-04959956v1
Cellulose fonctionnalisée par un heptyl-mannose: un nouvel outil thérapeutique et diagnostic ciblant les Escherichia coli adherents et invasifs Adeline Sivignon,Madeleine Cauwel,Clarisse Bridot,Medy C. Nongbe,David Deniaudet al. 15eme congres national de la SFM, Sep 2019, Paris, France Poster de conférence hal-02338687v1

Brevet (6)

GLYCOSIDE INHIBITORS OF YEAST Adeline Sivignon,Nathalie Ballet,Pascal Vandekerckove,Yann Guerardel,Shin-Yi Yuet al. France, Patent n° : WO2022FR50459 20220315. 2021 Brevet hal-04959168v1
Detection of pathogenic bacteria by chemically functionnalized cellulose Adeline Sivignon,S.G. Gouin,Francois-Xavier Felpin,Nicolas Barnich France, Patent n° : WO2020260445. 2019 Brevet hal-04959156v1
MANNOSE DERIVATIVES USEFUL FOR TREATING PATHOLOGIES ASSOCIATED WITH ADHERENT E. COLI Adeline Sivignon,Sebastien G. Gouin,Dimitri Alexander Alvarez-Dorta,François-Xavier Bellamy,Thibault Chalopinet al. France, Patent n° : WO2016EP68813 20160805. 2015 Brevet hal-04959204v1
ORALLY AVAILABLE COMPOUNDS, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS ANTI-ADHESIVE DRUGS FOR TREATING E. COLI INDUCED INFLAMMATORY BOWEL DISEASES SUCH AS CROHN'S DISEASE Adeline Sivignon,J. Bouckaert,S.G. Gouin,Dimitri Alvarez-Dorta,Nao Yamakawaet al. France, Patent n° : WO2015EP51415 20150123. 2014 Brevet hal-04959183v1
Mannose derivatives, a process for preparing the same and their uses as a drug Adeline Sivignon,Arlette Darfeuille-Michaud,J. Bouckaert,Rostyslav Bilyy,S.G. Gouinet al. France, Patent n° : WO2013EP65668 20130724. 2012 Brevet hal-04959197v1
COMPOSITION FOR HUMAN AND/OR ANIMAL NUTRITION, USES THEREOF AND YEASTS Adeline Sivignon,Georges Pignede,Jean-Luc Simon,Pascal Vandekerckove,Daniel Poulainet al. France, Patent n° : WO2008FR01729 20081212. 2007 Brevet hal-04959186v1

Pré-publication, Document de travail (1)

Targeting Sialic Acid Catabolism with Polyvalent Sialidase Inhibitors to Mitigate Bacterial Inflammation in the gut Mélyne Baudin Marie,Zoé Oblette,Mathieu Scalabrini,Denis Loquet,Devon W Kavanaughet al. 2025 Pré-publication, Document de travail hal-05382147v1

Thèse (1)

Stratégies prophylactiques et thérapeutiques visant à limiter les Escherichia coli Adhérents-Invasifs (AIEC) du tractus digestif dans le contexte de la maladie de Crohn Adeline Sivignon Sciences du Vivant [q-bio]. université clermont auvergne, 2015. Français. ⟨NNT : ⟩ Thèse tel-04959138v1