Adriana Erica Miele

Publications

Article dans une revue (23)

Structural Characterization of Murine Phosphodiesterase 5 Isoforms and Involvement of Cysteine Residues in Supramolecular Assembly Mauro Giorgi,Adriana Erica Miele,Silvia Cardarelli,Alessandra Giorgi,Mara Massimiet al. International Journal of Molecular Sciences, 2023, 24 (2), pp.1108. ⟨10.3390/ijms24021108⟩ Article dans une revue hal-03989112v1
Revisiting Schistosoma mansoni Micro-Exon Gene (MEG) Protein Family: A Tour into Conserved Motifs and Annotation Štěpánka Nedvědová,Davide de Stefano,Olivier Walker,Maggy Hologne,Adriana Erica Miele Biomolecules, 2023, 13 (9), pp.1275. ⟨10.3390/biom13091275⟩ Article dans une revue hal-04189192v1
Cellular Redox Metabolism Is Modulated by the Distinct Localization of Cyclic Nucleotide Phosphodiesterase 5A Isoforms Silvia Cardarelli,Adriana Erica Miele,Federica Campolo,Mara Massimi,Patrizia Manciniet al. International Journal of Molecular Sciences, 2022, 23 (15), pp.8587. ⟨10.3390/ijms23158587⟩ Article dans une revue hal-04004278v1
The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding Cecilia Rocchi,Camille Louvat,Adriana Miele,Julien Batisse,Christophe Guillonet al. International Journal of Molecular Sciences, 2022, 23 (22), pp.13742. ⟨10.3390/ijms232213742⟩ Article dans une revue hal-03434126v1
Biophysical characterization of the complex between the iron-responsive transcription factor Fep1 and DNA Adriana Miele,Laura Cervoni,Aline Le Roy,Antimo Cutone,Giovanni Musciet al. European Biophysics Journal, 2021, ⟨10.1007/s00249-020-01489-y⟩ Article dans une revue hal-03163020v1
Omic approaches to decipher the molecular mechanisms of fibrosis, and design new anti-fibrotic strategies Sylvie Ricard-Blum,Adriana E Miele Seminars in Cell and Developmental Biology, 2020, 101, pp.161-169. ⟨10.1016/j.semcdb.2019.12.009⟩ Article dans une revue (article de synthèse) hal-04998726v1
A comparative analysis of secreted protein disulfide isomerases from the tropical co-endemic parasites Schistosoma mansoni and Leishmania major Adriana E Miele,Sofiane Badaoui,Lorenzo Maugliani,Romain Salza,Giovanna Boumiset al. Scientific Reports, 2019, 9 ((1)), pp.9568. ⟨10.1038/s41598-019-45709-8⟩ Article dans une revue hal-04963995v1
Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners Sylvain Vallet,Adriana Miele,Urszula Uciechowska-Kaczmarzyk,Adam Liwo,Bertrand Ducloset al. Scientific Reports, 2018, 8 (1), pp.122-149. ⟨10.1038/s41598-018-30190-6⟩ Article dans une revue hal-02109680v1
Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as “Doorstop” for NADPH Entry Ilaria Silvestri,Haining Lyu,Francesca Fata,Giovanna Boumis,Adriana Mieleet al. ACS Chemical Biology, 2018, 13 (8), pp.2190-2202. ⟨10.1021/acschembio.8b00349⟩ Article dans une revue hal-02109710v1
The oligomeric assembly of the phosphodiesterase-5 is a mixture of dimers and tetramers: A putative role in the regulation of function Silvia Cardarelli,Adriana Erica Miele,Carlotta Zamparelli,Stefano Biagioni,Fabio Naroet al. Biochimica et Biophysica Acta (BBA) - General Subjects, 2018, 1862 (10), pp.2183-2190. ⟨10.1016/j.bbagen.2018.07.010⟩ Article dans une revue hal-02109690v1
Pichia pastoris Fep1 is a [2Fe-2S] protein with a Zn finger that displays an unusual oxygen-dependent role in cluster binding Antimo Cutone,Barry D. Howes,Adriana E. Miele,Rossella Miele,Alessandra Giorgiet al. Scientific Reports, 2016, 6 (31872), pp.1-12. ⟨10.1038/srep31872⟩ Article dans une revue hal-01541882v1
Hemoglobin allostery: new views on old players. Adriana Erica Miele,Andrea Bellelli,Maurizio Brunori Journal of Molecular Biology, 2013, 425 (9), pp.1515-26. ⟨10.1016/j.jmb.2012.12.018⟩ Article dans une revue pasteur-01025328v1
Switching between the alternative structures and functions of a 2-Cys peroxiredoxin, by site-directed mutagenesis. F. Angelucci,F. Saccoccia,M. Ardini,G. Boumis,M. Brunoriet al. Journal of Molecular Biology, 2013, 425 (22), pp.4556-68. ⟨10.1016/j.jmb.2013.09.002⟩ Article dans une revue pasteur-01022642v1
Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target. Giovanna Boumis,Giorgio Giardina,Francesco Angelucci,Andrea Bellelli,Maurizio Brunoriet al. Biochemical and Biophysical Research Communications, 2012, 425 (4), pp.806-11. ⟨10.1016/j.bbrc.2012.07.156⟩ Article dans une revue pasteur-00952042v1
Moonlighting by different stressors: crystal structure of the chaperone species of a 2-Cys peroxiredoxin. Fulvio Saccoccia,Patrizio Di Micco,Giovanna Boumis,Maurizio Brunori,Ilias Koutriset al. Structure, 2012, 20 (3), pp.429-39. ⟨10.1016/j.str.2012.01.004⟩ Article dans une revue pasteur-00952065v1
On the mechanism and rate of gold incorporation into thiol-dependent flavoreductases. Fulvio Saccoccia,Francesco Angelucci,Giovanna Boumis,Maurizio Brunori,Adriana E Mieleet al. Journal of Inorganic Biochemistry, 2012, 108, pp.105-11. ⟨10.1016/j.jinorgbio.2011.11.005⟩ Article dans une revue pasteur-00952028v1
Structural and functional characterization of Schistosoma mansoni Thioredoxin. Giovanna Boumis,Francesco Angelucci,Andrea Bellelli,Maurizio Brunori,Daniela Dimastrogiovanniet al. Protein Science, 2011, 20 (6), pp.1069-76. ⟨10.1002/pro.634⟩ Article dans une revue pasteur-00975317v1
Pattern of cavities in globins: the case of human hemoglobin. Carmelinda Savino,Adriana E Miele,Federica Draghi,Kenneth A Johnson,Giuliano Sciaraet al. Biopolymers, 2009, 91 (12), pp.1097-1107. ⟨10.1002/bip.21201⟩ Article dans une revue istex hal-01617675v1
Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate. Carmelinda Savino,Linda C Montemiglio,Giuliano Sciara,Adriana E Miele,Steven G Kendrewet al. Journal of Biological Chemistry, 2009, 284 (42), pp.29170-9. ⟨10.1074/jbc.M109.003590⟩ Article dans une revue hal-01617673v1
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of C-12 hydroxylase EryK from Saccharopolyspora erythraea. Carmelinda Savino,Giuliano Sciara,Adriana E Miele,Steven G Kendrew,Beatrice Vallone Protein and Peptide Letters, 2008, 15 (10), pp.1138-1141. ⟨10.2174/092986608786071201⟩ Article dans une revue hal-01617667v1
The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis. Giuliano Sciara,Steven G Kendrew,Adriana E Miele,Neil G Marsh,Luca Federiciet al. EMBO Journal, 2003, 22 (2), pp.205-15. ⟨10.1093/emboj/cdg031⟩ Article dans une revue hal-01595326v1
Analysis of the effect of microgravity on protein crystal quality: the case of a myoglobin triple mutant. Adriana E Miele,Luca Federici,Giuliano Sciara,Federica Draghi,Maurizio Brunoriet al. Acta crystallographica Section D : Structural biology [1993-..], 2003, 59 (6), pp.982-928 Article dans une revue hal-01595187v1
Complex landscape of protein structural dynamics unveiled by nanosecond Laue crystallography. Dominique Bourgeois,Beatrice Vallone,Friedrich Schotte,Alessandro Arcovito,Adriana E Mieleet al. Proceedings of the National Academy of Sciences of the United States of America, 2003, 100 (15), pp.8704-9. ⟨10.1073/pnas.1430900100⟩ Article dans une revue hal-01595186v1

Communication dans un congrès (2)

Unveiling the Enigma: Structural Insights into Schistosoma mansoni MEG Proteins Stepanka Nedvedova,Florence Guillière,Adriana E. Miele,François-Xavier Cantrelle,Davide de Stefanoet al. AILM 2024, May 2024, Grenoble, France Communication dans un congrès hal-04967921v1
Integrative structural biology in molecular parasitology: new strategies for old diseases Adriana E. Miele,Angelucci Francesco,Boumis Giovanna,Silvestri Ilaria,Fata Francescaet al. Protein Data Bank Symposium - 50th Year Celebration, ASBMB | AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, May 2021, online, United States Communication dans un congrès hal-04004310v1

Poster de conférence (1)

Shistosoma mansoni MEG family proteins in the environment of host-parasite interactions Stepanka Nedvedova,Maggy Hologne,Adriana E. Miele 21st European Conference on Computational Biology, Sep 2022, Barcelone (Espagne), Spain Poster de conférence hal-04005911v1

N°spécial de revue/special issue (1)

MOlecular BIophysics in EUrope - Integrating Molecular Biophysics Approaches in Biology, Chemistry and Healthcare; COST Action 15126 Bastos Margarida,Campos-Olivas Ramón,Jowitt Thomas A.,Knauer Stefan H.,Adriana E. Miele European Biophysics Journal, 50 (3-4), pp.307-670, 2021 N°spécial de revue/special issue hal-04004352v1