Alain Bousquet-Mélou

Identifiants chercheurs

IdHAL :

alain-bousquet-melou

ORCID :

0000-0002-7661-4311

IdRef :

059552964

Publications

Article dans une revue (159)

Reassessment of extracellular and intracellular activity of macrolides, rifampicin, and doxycycline against Rhodococcus equi based on bacterial counts and microscopy Anne-Sophie Huguet,Ophélie Gourbeyre,Alain Bousquet-Mélou,Aude A Ferran,Elodie A Lallemand Microbiology Spectrum, 2025, 13 (9), pp.e01205-25. ⟨10.1128/spectrum.01205-25⟩ Article dans une revue hal-05360313v1
Pharmacokinetics, pharmacodynamics, and local tolerance at injection site of penicillin and gentamicin administered by intravenous regional limb perfusion in standing horses: comparison between weightbearing and flexed limbs Marguerite Guillot,Céline Mespoulhes-Rivière,Alain Bousquet-Mélou,Marlène Z Lacroix,Béatrice B Roqueset al. BMC Veterinary Research, 2025, 21 (1), pp.650. ⟨10.1186/s12917-025-04936-0⟩ Article dans une revue hal-05360282v1
Pharmacokinetic–Pharmacodynamic Cutoff Values for Doxycycline in Pigs to Support the Establishment of Clinical Breakpoints for Antimicrobial Susceptibility Testing Pierre‐louis Toutain,Alain Bousquet‐melou,Aude A Ferran,Béatrice B Roques,Jérôme R E del Castilloet al. Journal of Veterinary Pharmacology and Therapeutics, 2025, ⟨10.1111/jvp.13511⟩ Article dans une revue hal-05046560v1
Development of an in vitro biofilm model for the study of the impact of fluoroquinolones on sewer biofilm microbiota Sarah A Naudin,Aude A Ferran,Pedro Henrique Imazaki,Nathalie Arpaillange,Camille Marcuzzoet al. Frontiers in Microbiology, 2024, 15, ⟨10.3389/fmicb.2024.1377047⟩ Article dans une revue hal-04522705v1
Antimicrobial combinations against &lt;i&gt;Helicobacter pylori&lt;/i&gt; including benzoxadiazol-based flavodoxin inhibitors: &lt;i&gt;in vitro&lt;/i&gt; characterization Lilha Beyria,Ophelie Gourbeyre,Sandra Salillas,Alejandro Mahía,María Dolores Díaz de Villegaset al. Microbiology Spectrum, 2024, 12 (1), ⟨10.1128/spectrum.02623-23⟩ Article dans une revue hal-04352359v1
Presencia de residuos antibióticos en carnes comercializadas en el área transfronteriza España‑Francia: un enfoque novedoso en los métodos de vigilancia María Jesús Serrano,Janira Elorduy,Itsaso Zabaleta,Georges Istamboulie,Elena González-Fandoset al. ITEA, información técnica económica agraria: revista de la Asociación Interprofesional para el Desarrollo Agrario (AIDA), 2024, 120 (3), pp.251-268. ⟨10.12706/itea.2024.001⟩ Article dans une revue hal-04682445v1
Potentialities of semi-continuous anaerobic digestion for mitigating antibiotics in sludge Amine Ezzariai,Julie Jimenez,Maialen Barret,David Riboul,Marlène Z Lacroixet al. Environmental Science and Pollution Research, 2024, 31, pp.66067-66078. ⟨10.1007/s11356-024-35664-x⟩ Article dans une revue hal-04886552v1
The sub-MIC selective window decreases along the digestive tract: determination of the minimal selective concentration of oxytetracycline in sterilised intestinal contents Pedro Henrique Imazaki,Bertille Voisin,Béatrice Roques,Emilie Dordet-Frisoni,Véronique Dupouyet al. Frontiers in Microbiology, 2024, 15 (22), pp.1803-1804. ⟨10.3389/fmicb.2024.1377159⟩ Article dans une revue hal-04700337v1
Comparative bactericidal activity of four macrolides alone and combined with rifampicin or doxycycline against Rhodococcus equi at concentrations achievable in foals Anne-Sophie Huguet,Ophélie Gourbeyre,Agathe Bernand,Charline Philibert,Alain Bousquet-Melouet al. Frontiers in Pharmacology, 2024, 15, pp.1458496. ⟨10.3389/fphar.2024.1458496⟩ Article dans une revue hal-04816942v1
Predicted efficacy and tolerance of different dosage regimens of benzylpenicillin in horses based on a pharmacokinetic study with three IM formulations and one IV formulation Aude A. Ferran,Béatrice Roques,Laura Chapuis,Taisuke Kuroda,Marlène Lacroixet al. Frontiers in Veterinary Science, 2024, 11, pp.1409266. ⟨10.3389/fvets.2024.1409266⟩ Article dans une revue hal-04644781v1
Development of HPV16 mouse and dog models for more accurate prediction of human vaccine efficacy Emmanuelle Totain,Loic Lindner,Nicolas Martin,Yolande Misseri,Alexandra Ichéet al. Laboratory Animal Research, 2023, 39 (1), pp.14. ⟨10.1186/s42826-023-00166-3⟩ Article dans une revue hal-04750862v1
Pharmacokinetic-pharmacodynamic cutoff values for benzylpenicillin in horses to support the establishment of clinical breakpoints for benzylpenicillin antimicrobial susceptibility testing in horses. Elodie A Lallemand,Alain Bousquet-Mélou,Laura Chapuis,Jennifer Davis,Aude Ferranet al. Frontiers in Microbiology, 2023, 14, pp.1282949. ⟨10.3389/fmicb.2023.1282949⟩ Article dans une revue hal-04352390v1
Residues of veterinary antibiotics in manures from pig and chicken farms in a context of antimicrobial use reduction by implementation of health and welfare plans Marlene Lacroix,Felipe Ramon-Portugal,Alicia Huesca,Kyriacos Angastiniotis,Maro Simitopoulouet al. Environmental Research, 2023, 238, pp.117242. ⟨10.1016/j.envres.2023.117242⟩ Article dans une revue hal-04235091v1
Biased computation of probability of target attainment for antimicrobial drugs Pierre‐louis Toutain,Peggy Gandia,Ludovic Pelligand,Aude Ferran,Peter Leeset al. CPT: Pharmacometrics and Systems Pharmacology, 2023, 12 (5), pp.681-689. ⟨10.1002/psp4.12929⟩ Article dans une revue hal-04061755v1
Doxycycline serum protein binding in pigs reveals a relatively high free fraction Felipe Ramon Portugal,Marlène Lacroix,Béatrice Roques,Véronique V. Gayrard-Troy,Pierre‐louis Toutainet al. Journal of Veterinary Pharmacology and Therapeutics, 2023, ⟨10.1111/jvp.13111⟩ Article dans une revue hal-03989935v1
The Selection of Antibiotic- and Bacteriophage-Resistant Pseudomonas aeruginosa Is Prevented by Their Combination Aude A Ferran,Marlène Z Lacroix,Ophélie Gourbeyre,Alicia Huesca,Baptiste Gaborieauet al. Microbiology Spectrum, 2022, 10 (5), pp.e0287422. ⟨10.1128/spectrum.02874-22⟩ Article dans une revue hal-03888726v1
Combining sequential extraction and 3D fluorescence to investigate the behavior of antibiotic and polycyclic aromatic hydrocarbons during solar drying of sewage sludge Amine Ezzariai,Amal An-Nori,Loubna El Fels,David Riboul,Georges Merlinaet al. Chemosphere, 2022, 298, pp.134293. ⟨10.1016/j.chemosphere.2022.134293⟩ Article dans une revue hal-03684696v1
Sequential removal of human antibiotics as a function of the dynamic of organic matter fractions and 3D fluorescence during sludge composting Amine Ezzariai,Eric Pinelli,Loubna El Fels,Georges Merlina,David Riboulet al. Journal of Environmental Chemical Engineering, 2022, 10 (3), pp.107956. ⟨10.1016/j.jece.2022.107956⟩ Article dans une revue hal-03766238v1
Repeated Exposure of Escherichia coli to High Ciprofloxacin Concentrations Selects gyrB Mutants That Show Fluoroquinolone-Specific Hyperpersistence Aurore Perault,Catherine Turlan,Nathalie Eynard,Quentin Vallé,Alain Bousquet-Mélouet al. Frontiers in Microbiology, 2022, 13, pp.908296. ⟨10.3389/fmicb.2022.908296⟩ Article dans une revue hal-03708916v1
Rational dosage regimens for cephalothin and cefazolin using pharmacokinetics and pharmacodynamics analysis in healthy horses Taisuke Kuroda,Yohei Minamijima,Hidekazu Niwa,Norihisa Tamura,Hiroshi Mitaet al. Equine Veterinary Journal, 2021, ⟨10.1111/evj.13406⟩ Article dans une revue hal-03204606v1
Antipoxvirus Activity Evaluation of Optimized Corroles Based on Development of Autofluorescent ANCHOR Myxoma Virus Sandrine Kappler-Gratias,Léo Bucher,Sokunthea Top,Charlotte Quentin-Froignant,Nicolas Desboiset al. ACS Infectious Diseases, 2021, 7 (8), pp.2370-2382. ⟨10.1021/acsinfecdis.1c00068⟩ Article dans une revue hal-03334449v1
Characterization and quantification of chlordecone elimination in ewes Maïlie Saint-Hilaire,Aurore Fourcot,Alain Bousquet-Mélou,Guido Rychen,Jean-Pierre Thoméet al. Environmental Toxicology and Pharmacology, 2021, 87, pp.103698. ⟨10.1016/j.etap.2021.103698⟩ Article dans une revue hal-03515239v1
Dynamic interactions between cephalexin and macrophages on different Staphylococcus aureus inoculum sizes: a tripartite in vitro model Elodie A Lallemand,Claudine Zemirline,Pierre-Louis Toutain,Alain Bousquet‐mélou,Aude Ferranet al. BMC Veterinary Research, 2021, 17 (1), ⟨10.1186/s12917-021-02746-8⟩ Article dans une revue hal-03198305v1
Prediction of Minocycline Activity in the Gut From a Pig Preclinical Model Using a Pharmacokinetic -Pharmacodynamic Approach Quentin Vallé,Béatrice Roques,Alain Bousquet-Mélou,David Dahlhaus,Felipe Ramon-Portugalet al. Frontiers in Microbiology, 2021, 12, ⟨10.3389/fmicb.2021.671376⟩ Article dans une revue hal-03319354v1
Towards a Better and Harmonized Education in Antimicrobial Stewardship in European Veterinary Curricula Carmen Espinosa-Gongora,Lisbeth Jessen,Oliver Dyar,Alain Bousquet‐mélou,Bruno González-Zornet al. Antibiotics, 2021, 10 (4), pp.364. ⟨10.3390/antibiotics10040364⟩ Article dans une revue hal-03190794v1
Selection of ESBL-producing Escherichia coli in the gut of calves experimentally fed with milk containing antibiotic residues Véronique Dupouy,Jean-Yves Madec,Jessica Wucher,Nathalie Arpaillange,Véronique Métayeret al. Veterinary Microbiology, 2021, 257, pp.109049. ⟨10.1016/j.vetmic.2021.109049⟩ Article dans une revue hal-03279732v1
Destruction of Staphylococcus aureus biofilms by combining an antibiotic with subtilisin A or calcium gluconate Jingjing Liu,Jean-Yves Madec,Alain Bousquet‐mélou,Marisa Haenni,Aude Ferran Scientific Reports, 2021, 11 (1), pp.1-12. ⟨10.1038/s41598-021-85722-4⟩ Article dans une revue hal-03194522v1
Population Pharmacokinetics of Intravenous Amoxicillin Combined With Clavulanic Acid in Healthy and Critically Ill Dogs Maria D Vegas Cómitre,Stefano Cortellini,Marc Cherlet,Mathias Devreese,Beatrice B Roqueset al. Frontiers in Veterinary Science, 2021, 8, ⟨10.3389/fvets.2021.770202⟩ Article dans une revue hal-03516328v1
A Large Impact of Obesity on the Disposition of Ivermectin, Moxidectin and Eprinomectin in a Canine Model: Relevance for COVID-19 Patients Alain Bousquet-Mélou,Anne Lespine,Jean-François Sutra,Isabelle Bargues,Pierre-Louis Toutain Frontiers in Pharmacology, 2021, 12, ⟨10.3389/fphar.2021.666348⟩ Article dans une revue hal-03260114v1
Determination of the pharmacokinetic‐pharmacodynamic cut‐off values of marbofloxacin in horses to support the establishment of a clinical breakpoint for antimicrobial susceptibility testing Alain Bousquet‐mélou,Marc Schneider,Farid El Garch,Diane Broussou,Aude Ferranet al. Equine Veterinary Journal, 2020, ⟨10.1111/evj.13385⟩ Article dans une revue hal-03113834v1
Early inoculation of microbial suspension in suckling piglets affects the transmission of maternal microbiota and the associated antibiotic resistance genes Caroline Achard,Véronique Dupouy-Guiraute,Laurent Cauquil,Nathalie Arpaillange,Alain Bousquet‐mélouet al. Microorganisms, 2020, 8 (10), pp.1576. ⟨10.3390/microorganisms8101576⟩ Article dans une revue hal-03106275v1
Authors' Reply to Yu et al.: &quot;&quot;Levothyrox® New and Old Formulations: Are They Switchable for Millions of Patients? Didier Concordet,Peggy Gandia,Jean-Louis Montastruc,Alain Bousquet‐mélou,Peter Leeset al. Clinical Pharmacokinetics, 2020, ⟨10.1007/s40262-019-00852-3⟩ Article dans une revue hal-02619187v1
Authors' Reply to Krebs-Brown et al. Comment on: &quot;Why Were More Than 200 Subjects Required to Demonstrate the Bioequivalence of a New Formulation of Levothyroxine with an Old One? Didier Concordet,Peggy Gandia,J L Montastruc,Alain Bousquet‐mélou,P Leeset al. Clinical Pharmacokinetics, 2020, ⟨10.1007/s40262-019-00848-z⟩ Article dans une revue hal-02627432v1
Why Were More Than 200 Subjects Required to Demonstrate the Bioequivalence of a New Formulation of Levothyroxine with an Old One? Didier Concordet,Peggy Gandia,Jean-Louis Montastruc,Alain Bousquet‐mélou,Peter Leeset al. Clinical Pharmacokinetics, 2020, ⟨10.1007/s40262-019-00812-x⟩ Article dans une revue hal-02624662v1
The pharmacokinetic/pharmacodynamic paradigm for antimicrobial drugs in veterinary medicine: Recent advances and critical appraisal Pierre‐louis Toutain,Ludovic Pelligand,Peter Lees,Alain Bousquet‐mélou,Aude Ferranet al. Journal of Veterinary Pharmacology and Therapeutics, 2020, 44 (2), pp.172-200. ⟨10.1111/jvp.12917⟩ Article dans une revue (article de synthèse) hal-03133155v1
Antibiotic resistance: Tools for effective translational research Marie-Cécile Ploy,Antoine Andremont,Bruno Valtier,Claire Le Jeunne,Catherine Dumartinet al. Therapies, 2020, Giens Workshops 2019, 75 (1), pp.7-12. ⟨10.1016/j.therap.2019.12.003⟩ Article dans une revue hal-02516924v1
Modeling chlordecone toxicokinetics data in growing pigs using a nonlinear mixed-effects approach A. Fourcot,C. Feidt,Alain Bousquet‐mélou,A.A. Ferran,Jean-Luc Gourdineet al. Chemosphere, 2020, 250, pp.126151. ⟨10.1016/j.chemosphere.2020.126151⟩ Article dans une revue hal-02935835v1
Authors' Reply to Nicolas: &quot;Why Were More than 200 Subjects Required to Demonstrate the Bioequivalence of a New Formulation of Levothyroxine with an Old One? Didier Concordet,Peggy Gandia,Jean-Louis Montastruc,Alain Bousquet‐mélou,Peter Leeset al. Clinical Pharmacokinetics, 2020, ⟨10.1007/s40262-019-00851-4⟩ Article dans une revue hal-02627433v1
Is Blood a Good Indicator for Detecting Antimicrobials in Meat? Evidence for the Development of In Vivo Surveillance Methods María Jesús Serrano,Olga Mitjana,Cristina Bonastre,Alicia Laborda,María Victoria Falcetoet al. Antibiotics, 2020, 9 (4), pp.175. ⟨10.3390/antibiotics9040175⟩ Article dans une revue hal-03127743v1
Levers to Improve Antibiotic Treatment of Lambs via Drinking Water in Sheep Fattening Houses: The Example of the Sulfadimethoxine/Trimethoprim Combination Aude Ferran,Marlène Z. Lacroix,Alain Bousquet‐mélou,Ivain Duhil,Béatrice Roques Antibiotics, 2020, 9 (9), pp.561. ⟨10.3390/antibiotics9090561⟩ Article dans une revue hal-02955180v1
Antibiorésistance : outils pour une recherche translationnelle efficace Marie-Cécile Ploy,Antoine Andremont,Bruno Valtier,Claire Le Jeunne,Catherine Dumartinet al. Therapies, 2020, 75 (1), pp.1-6. ⟨10.1016/j.therap.2019.12.001⟩ Article dans une revue hal-02440782v1
Authors' Reply to Nicolas:&quot;New and Old Formulations: Are they Switchable for Millions of Patients? Didier Concordet,Peggy Gandia,Jean-Louis Montastruc,Alain Bousquet‐mélou,Peter Leeset al. Clinical Pharmacokinetics, 2019, 58 (7), pp.961-963. ⟨10.1007/s40262-019-00781-1⟩ Article dans une revue hal-02620199v1
Comparison of in vitro static and dynamic assays to evaluate the efficacy of an antimicrobial drug combination against Staphylococcus aureus Diane Broussou,Pierre-Louis Toutain,Frédérique Woehrlé,Farid El Garch,Alain Bousquet‐mélouet al. PLoS ONE, 2019, 14 (1), pp.e0211214. ⟨10.1371/journal.pone.0211214⟩ Article dans une revue hal-01998871v1
Authors' Reply to Coste et al.:&quot;Levothyrox New and Old Formulations: Are they Switchable for Millions of Patients? Didier Concordet,Peggy Gandia,Jean-Louis Montastruc,Alain Bousquet‐mélou,Peter Leeset al. Clinical Pharmacokinetics, 2019, 58 (7), pp.967-968. ⟨10.1007/s40262-019-00780-2⟩ Article dans une revue hal-02623560v1
Variability of the Ability of Complex Microbial Communities to Exclude Microbes Carrying Antibiotic Resistance Genes in Rabbits Caroline Achard,Véronique Dupouy-Guiraute,Suzanne Siviglia,Nathalie Arpaillange,Laurent Cauquilet al. Frontiers in Microbiology, 2019, 10, ⟨10.3389/fmicb.2019.01503⟩ Article dans une revue hal-02619189v1
Comparison of hydroalcoholic rubbing and conventional chlorhexidine scrubbing for aseptic skin preparation in dogs Erik Asimus,Sophie Palierne,Margaux Blondel,Valentine Pollet,Aude Ferranet al. Veterinary Surgery, 2019, 48 (8), pp.1466-1472. ⟨10.1111/vsu.13222⟩ Article dans une revue hal-02620124v1
Pharmacokinetics of Ertapenem in Sheep (Ovis aries) with Experimentally Induced Urinary Tract Infection. Joe S Smith,David J Borts,Clare C Slagel,Suzanne M Rajewski,Alain Bousquet‐mélouet al. Comparative Medicine, 2019, 69 (5), pp.413-418. ⟨10.30802/AALAS-CM-18-000144⟩ Article dans une revue hal-02624660v1
Authors' Reply to Lechat et al.: &quot; New and Old Formulations: Are they Switchable for Millions of Patients? Didier Concordet,Peggy Gandia,Jean-Louis Montastruc,Alain Bousquet‐mélou,Peter Leeset al. Clinical Pharmacokinetics, 2019, 58 (10), pp.1353-1354. ⟨10.1007/s40262-019-00815-8⟩ Article dans une revue hal-02619071v1
Authors'Reply to Castello-Bridoux et al.:&quot;Comment on Levothyrox® New and Old Formulations: Are they Switchable for Millions of Patients? Didier Concordet,Peggy Gandia,Jean-Louis Montastruc,Alain Bousquet‐mélou,Peter Leeset al. Clinical Pharmacokinetics, 2019, 58 (7), pp.973-975. ⟨10.1007/s40262-019-00786-w⟩ Article dans une revue hal-02627694v1
Levothyrox® New and Old Formulations: Are they Switchable for Millions of Patients? Didier Concordet,Peggy Gandia,Jean-Louis Montastruc,Alain Bousquet‐mélou,Peter Leeset al. Clinical Pharmacokinetics, In press, 58 (7), pp.827-833. ⟨10.1007/s40262-019-00747-3⟩ Article dans une revue hal-02095017v1
Author's Reply to Trechot: &quot;Comment on Levothyrox® New and Old Formulations: Are they Switchable for Millions of Patients? Didier Concordet,Peggy Gandia,Jean-Louis Montastruc,Alain Bousquet‐mélou,Peter Leeset al. Clinical Pharmacokinetics, 2019, 58 (7), pp.979-980. ⟨10.1007/s40262-019-00787-9⟩ Article dans une revue hal-02619069v1
Prevalence of Beta-Lactam and Quinolone/ Fluoroquinolone Resistance in Enterobacteriaceae From Dogs in France and Spain-Characterization of ESBL/pAmpC Isolates, Genes, and Conjugative Plasmids. Véronique Dupouy-Guiraute,Mouni Abdelli,Gabriel Moyano,Nathalie Arpaillange,Delphine Bibbalet al. Frontiers in Veterinary Science, 2019, 6, ⟨10.3389/fvets.2019.00279⟩ Article dans une revue hal-02619188v1
Population Pharmacokinetic Study of Cefazolin Used Prophylactically in Canine Surgery for Susceptibility Testing Breakpoint Determination Petra Cagnardi,Federica Di Cesare,Pierre-Louis Toutain,Alain Bousquet‐mélou,Giuliano Ravasioet al. Frontiers in Pharmacology, 2018, 9, ⟨10.3389/fphar.2018.01137⟩ Article dans une revue hal-02621740v1
Mixing of &lt;em&gt;Shiga&lt;/em&gt; toxin-producing and enteropathogenic &lt;em&gt;Escherichia coli&lt;/em&gt; in a wastewater treatment plant receiving city and slaughterhouse wastewater Delphine Bibbal,Maryse Michèle Um,Alpha-Amadou Diallo,Monique M. Kérourédan,Véronique Dupouy-Guirauteet al. International Journal of Hygiene and Environmental Health, 2018, 221 (2), pp.355-363. ⟨10.1016/j.ijheh.2017.12.009⟩ Article dans une revue istex hal-02621372v1
KN Antimicrobials - The EU approach to antimicrobial susceptibility testing: science, stewardship and regulation (the EU VetCAST project) Ludovic Pelligand,Pierre-Louis Toutain,Alain Bousquet‐mélou,P. Damborg,Aude A. Ferranet al. Journal of Veterinary Pharmacology and Therapeutics, 2018, 41, pp.16 Article dans une revue hal-02619945v1
A pressurized liquid extraction approach followed by standard addition method and UPLC-MS/MS for a fast multiclass determination of antibiotics in a complex matrix Amine Ezzariai,David Riboul,Marlène Z. Lacroix,Maialen Barret,Loubna El Felset al. Chemosphere, 2018, 211, pp.893-902. ⟨10.1016/j.chemosphere.2018.08.021⟩ Article dans une revue istex hal-02623075v1
Differential Activity of the Combination of Vancomycin and Amikacin on Planktonic vs. Biofilm-Growing Staphylococcus aureus Bacteria in a Hollow Fiber Infection Model. Diane Broussou,Marlène Z. Lacroix,Pierre-Louis Toutain,Frédérique Woehrle,Farid El Garchet al. Frontiers in Microbiology, 2018, 9, pp.572. ⟨10.3389/fmicb.2018.00572⟩ Article dans une revue hal-02620937v1
Implementing Precision Antimicrobial Therapy for the Treatment of Bovine Respiratory Disease: Current Limitations and Perspectives. Guillaume Lhermie,Pierre-Louis Toutain,Farid El Garch,Alain Bousquet‐mélou,Sébastien Assie Frontiers in Veterinary Science, 2017, 4, pp.143. ⟨10.3389/fvets.2017.00143⟩ Article dans une revue hal-01608694v1
Impact of low and high doses of marbofloxacin on the selection of resistant enterobacteriaceae in the commensal gut flora of young cattle: Discussion of data from 2 study populations Guillaume Lhermie,Véronique Dupouy-Guiraute,Farid El Garch,Nadine Ravinet,Pierre-Louis Toutainet al. Foodborne Pathogens and Disease, 2017, 14 (3), pp.152-159. ⟨10.1089/fpd.2016.2176⟩ Article dans une revue hal-01603817v1
Capacity limits of asialoglycoprotein receptor-mediated liver targeting Charlotte Bon,Thomas Höfer,Alain Bousquet‐mélou,Mark R. Davies,Ben-Fillippo Krippendorff mAbs, 2017, 9 (8), pp.1360-1369. ⟨10.1080/19420862.2017.1373924⟩ Article dans une revue hal-02627537v1
Infection-stage adjusted dose of beta-lactams for parsimonious and efficient antibiotic treatments: A Pasteurella multocida experimental pneumonia in mice Maleck V. Vasseur,Marlène Z. Lacroix,Pierre-Louis Toutain,Alain Bousquet‐mélou,Aude A. Ferran PLoS ONE, 2017, 12 (8), 14 p. ⟨10.1371/journal.pone.0182863⟩ Article dans une revue hal-01604263v1
En route towards european clinical breakpoints for veterinary antimicrobial susceptibility testing: A position paper explaining the VetCAST approach Pierre-Louis Toutain,Alain Bousquet‐mélou,Peter Damborg,Aude Ferran,Dik Meviuset al. Frontiers in Microbiology, 2017, 8, 12 p. ⟨10.3389/fmicb.2017.02344⟩ Article dans une revue hal-02628320v1
Prediction of human prenatal exposure to bisphenol A and bisphenol A glucuronide from an ovine semi-physiological toxicokinetic model Glenn Gauderat,Nicole Picard-Hagen,Pierre-Louis Toutain,Rémi Servien,Catherine Viguiéet al. Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-15646-5⟩ Article dans une revue hal-02628446v1
Comparison of the In vitro activity of five antimicrobial drugs against&lt;em&gt; Staphylococcus pseudintermedius&lt;/em&gt; and &lt;em&gt;Staphylococcus aureus&lt;/em&gt; Biofilms Aude Ferran,Jing Jing Liu,Pierre-Louis Toutain,Alain Bousquet‐mélou Frontiers in Microbiology, 2016, 7, pp.1187. ⟨10.3389/fmicb.2016.01187⟩ Article dans une revue hal-02631259v1
Bisphenol A glucuronide deconjugation is a determining factor of fetal exposure to bisphenol A. Glenn Gauderat,Nicole Picard-Hagen,Pierre-Louis Toutain,Tanguy Corbel,Catherine Viguiéet al. Environment International, 2016, 86, pp.52-9. ⟨10.1016/j.envint.2015.10.006⟩ Article dans une revue istex hal-02641312v1
Dominant plasmids carrying extended spectrum β-lactamases blaCTX-M genes in genetically diverse &lt;em&gt;Escherichia coli&lt;/em&gt; from slaughterhouse and urban wastewaters Véronique Dupouy-Guiraute,Benoît Doublet,Nathalie Arpaillange,Karine Praud,Delphine Bibbalet al. Environmental Microbiology Reports, 2016, 8 (5), pp.789-797. ⟨10.1111/1758-2229.12440⟩ Article dans une revue istex hal-02631274v1
Veterinary Medicine Needs New Green Antimicrobial Drugs. Pierre-Louis Toutain,Aude Ferran,Alain Bousquet‐mélou,Ludovic Pelligand,Peter Lees Frontiers in Microbiology, 2016, 7, ⟨10.3389/fmicb.2016.01196⟩ Article dans une revue (article de synthèse) hal-02632279v1
Impact of timing and dosage of a fluoroquinolone treatment on the microbiological, pathological, and clinical outcomes of calves challenged with Mannheimia haemolytica Guillaume Lhermie,Aude Ferran,Sébastien Assié,Hervé Cassard,Farid El Garchet al. Frontiers in Microbiology, 2016, 7, pp.1-13. ⟨10.3389/fmicb.2016.00237⟩ Article dans une revue hal-02633372v1
Schéma thérapeutique: Impact sur la résistance Alain Bousquet‐mélou La Dépêche Technique, 2016, 142, pp.10-13 Article dans une revue hal-01602477v1
In vitro degradation of antimicrobials during use of broth microdilution method can increase the measured minimal inhibitory and minimal bactericidal concentrations Elodie Anne Lallemand,Marlène Z. Lacroix,Pierre-Louis Toutain,Séverine Boullier,Aude Ferranet al. Frontiers in Microbiology, 2016, 7, pp.1-6. ⟨10.3389/fmicb.2016.02051⟩ Article dans une revue hal-01602449v1
Application of pharmacological principles to dosage design of antimicrobial drugs Peter Lees,Ludovic Pelligand,Aude Ferran,Alain Bousquet‐mélou,Pierre-Louis Toutain Pharmacology Matters, 2015, 8 (1) Article dans une revue hal-02633242v1
Bacterial Species-Specific Activity of a Fluoroquinolone against Two Closely Related Pasteurellaceae with Similar MICs: Differential In Vitro Inoculum Effects and In Vivo Efficacies. Guillaume Lhermie,Farid El Garch,Pierre-Louis Toutain,Aude Ferran,Alain Bousquet‐mélou PLoS ONE, 2015, 10 (10), pp.e0141441. ⟨10.1371/journal.pone.0141441⟩ Article dans une revue hal-02633630v1
Comment on &quot;In vitro effects of bisphenol A β-D-glucuronide (BPA-G) on adipogenesis in human and murine preadipocytes&quot;. Véronique V. Gayrard-Troy,Glenn Gauderat,Marlène Z. Lacroix,Catherine Viguié,Alain Bousquet‐mélouet al. Environmental Health Perspectives, 2015, 123 (12), pp.A289. ⟨10.1289/ehp.1510315⟩ Article dans une revue hal-02629934v1
Veterinary medicine needs new and innovative green antimicrobial drugs Pierre-Louis Toutain,Alain Bousquet‐mélou,Aude Ferran,Ludovic Pelligand,Peter Lees Pharmacology Matters, 2015, 8 (1), pp.20-21 Article dans une revue hal-02630755v1
Allometric scaling for predicting human clearance of bisphenol A Séverine Collet,Nicole Picard-Hagen,Marlène Z. Lacroix,Sylvie Puel,Catherine Viguiéet al. Toxicology and Applied Pharmacology, 2015, 284 (3), pp.323-9. ⟨10.1016/j.taap.2015.02.024⟩ Article dans une revue istex hal-02637966v1
Pharmacologie des anti-inflammatoires disponibles pour les animaux de rente Aude Ferran,Alain Bousquet‐mélou Bulletin des G.T.V., 2014, 76, pp.35-40 Article dans une revue (article de synthèse) hal-02630208v1
Problèmes et difficultés rencontrés lors de la planification et de l'analyse d'un essai de bioéquivalence. Pierre-Louis Toutain,Peggy Gandia,Alain Bousquet‐mélou La Lettre du Pharmacologue, 2014, 28 (2), pp.37-50 Article dans une revue hal-02630493v1
Prévention de la résistance aux antibiotiques: le bon usage dans les élevages et en médecine vétérinaire Alain Bousquet‐mélou Hygiènes, 2014, XXII (4) Article dans une revue hal-02629962v1
Rebuttal to the reaction of the EGGVP to the review article 'The consequences of generic marketing on antibiotic consumption and the spread of microbial resistance: the need for new antibiotics'. Pierre Louis Toutain,Alain Bousquet‐mélou Journal of Veterinary Pharmacology and Therapeutics, 2014, 37 (6), pp.618-23. ⟨10.1111/jvp.12166⟩ Article dans une revue istex hal-02630946v1
Comparison of the reduction in the antibacterial potency of a fluoroquinolone conferred by a single mutation in the quinolone resistance-determining region or by the inoculum size effect. Aude A Ferran,Pierre-Louis Toutain,Alain Bousquet‐mélou International Journal of Antimicrobial Agents, 2014, 44 (5), pp.472-4. ⟨10.1016/j.ijantimicag.2014.07.007⟩ Article dans une revue istex hal-02635372v1
Use of Monte Carlo simulation to determine pharmacodynamic cutoffs of amoxicillin to establish a breakpoint for antimicrobial susceptibility testing in pigs Julien Rey,Céline M. Laffont,Siska Croubels,Patrick de Backer,Claudine Zemirlineet al. American Journal of Veterinary Research, 2014, 75 (2), pp.124-31. ⟨10.2460/ajvr.75.2.124⟩ Article dans une revue hal-02641639v1
Low or high doses of cefquinome targeting low or high bacterial inocula cure Klebsiella pneumoniae lung infections but differentially impact the levels of antibiotic resistance in fecal flora. Maleck V. Vasseur,Michel Laurentie,Jean-Guy Rolland,Agnès Perrin-Guyomard,Jérôme Henriet al. Antimicrobial Agents and Chemotherapy, 2014, 58 (3), pp.1744-8. ⟨10.1128/AAC.02135-13⟩ Article dans une revue hal-00978511v1
High bioavailability of bisphenol A from sublingual exposure. Véronique V. Gayrard-Troy,Marlène Z. Lacroix,Séverine Collet,Catherine Viguié,Alain Bousquet‐mélouet al. Environmental Health Perspectives, 2013, 121 (8), pp.951-6. ⟨10.1289/ehp.1206339⟩ Article dans une revue hal-02645480v1
Interpreting bisphenol a absorption in the canine oral cavity: gayrard et Al. Respond. Véronique V. Gayrard-Troy,Marlène Z. Lacroix,Séverine Collet,Catherine Viguié,Alain Bousquet‐mélouet al. Environmental Health Perspectives, 2013, 121 (11-12), pp.A323-4. ⟨10.1289/ehp.1307424R⟩ Article dans une revue hal-02644875v1
The consequences of generic marketing on antibiotic consumption and the spread of microbial resistance: the need for new antibiotics Pierre-Louis Toutain,Alain Bousquet‐mélou Journal of Veterinary Pharmacology and Therapeutics, 2013, 36 (5), pp.420-424. ⟨10.1111/jvp.12061⟩ Article dans une revue istex hal-02645451v1
Pharmacokinetic/pharmacodynamic assessment of the effects of parenteral administration of a fluoroquinolone on the intestinal microbiota: Comparison of bactericidal activity at the gut versus the systemic level in a pig model. Aude A Ferran,Delphine Bibbal,Terence Pellet,Michel Laurentie,Mireille Gicquel-Bruneauet al. International Journal of Antimicrobial Agents, 2013, 42 (5), pp.429-35. ⟨10.1016/j.ijantimicag.2013.07.008⟩ Article dans une revue istex hal-00875291v1
Persistence and prevalence of pathogenic and extended-spectrum beta-lactamase-producing Escherichia coli in municipal wastewater treatment plant receiving slaughterhouse wastewater Alpha-Amadou Diallo,Hubert Brugère,Monique M. Kérourédan,Véronique Dupouy-Guiraute,Pierre-Louis Toutainet al. Water Research, 2013, 47 (13), pp.4719 - 4729. ⟨10.1016/j.watres.2013.04.047⟩ Article dans une revue istex hal-02645474v1
Susceptibility of Two European strains of Stomoxys calcitrans (L.) to Cypermethrin, Deltamethrin, Fenvalerate, lambda-cyhalothrin, Permethrin and Phoxim Ali Salem,Emilie Bouhsira,Emmanuel Liénard,Alain Bousquet‐mélou,Philippe Jacquietet al. The Journal of Applied Research in Veterinary Medicine, 2012, 10 (3), pp.249 - 257 Article dans une revue hal-02645910v1
Impact du schéma posologique sur la résistance. Alain Bousquet‐mélou,Aude Ferran,Pierre-Louis Toutain Bulletin des G.T.V., 2012, 64, pp.29-36 Article dans une revue hal-01136975v1
Le concept « One Health » en antibiorésistance et les flux de gènes Benoît Doublet,Alain Bousquet‐mélou,J.Y. Madec Innovations Agronomiques, 2012, 24, pp.79-90. ⟨10.17180/81bk-4946⟩ Article dans une revue hal-02642975v1
Assessment of the genotoxicity of quinolone and fluoroquinolones contaminated soil with the Vicia faba micronucleus test Ahmed Khadra,Eric Pinelli,Marlène Z. Lacroix,Alain Bousquet‐mélou,H Hamdiet al. Ecotoxicology and Environmental Safety, 2012, 76, pp.187-192. ⟨10.1016/j.ecoenv.2011.10.012⟩ Article dans une revue hal-01191262v1
Comment traiter une inflammation chez les bovins effets recherchés et effets indésirables des molécules anti-inflammatoires Aude Ferran,Alain Bousquet‐mélou,Pierre-Louis Toutain Le Nouveau Praticien Vétérinaire. Elevages et Santé, 2012, 5 (22), pp.58-64 Article dans une revue hal-02641849v1
Nouvelles stratégies en antibiothérapie Alain Bousquet‐mélou Pratique Veterinaire, 2012, 93, pp.3 Article dans une revue hal-02646746v1
Should licking behavior be considered in the bioavailability evaluation of transdermal products? Pierre-Louis Toutain,Sanja Modric,Alain Bousquet‐mélou,Juan M Sallovitz,Carlos Lanusse Journal of Veterinary Pharmacology and Therapeutics, 2012, 35, pp.39-43. ⟨10.1111/j.1365-2885.2012.01380.x⟩ Article dans une revue hal-01136992v1
Léchage entre congénères et antiparasitaires en [i]pour-on[/i]. Alain Bousquet‐mélou Le Point vétérinaire, 2012, 43, pp.124-126 Article dans une revue hal-01191268v1
Licking behaviour induces partial anthelmintic efficacy of ivermectin pour-on formulation in untreated cattle. Alain Bousquet‐mélou,Philippe Jacquiet,Hervé Hoste,Julien Clément,Jean-Paul Bergeaudet al. Int J Parasitol, 2011, 41 (5), epub ahead of print. ⟨10.1016/j.ijpara.2010.12.007⟩ Article dans une revue hal-00556815v1
Utilisation des antibiotiques en élevage et enjeux de santé publique Pascal Sanders,Alain Bousquet‐mélou,Claire Chauvin,Pierre-Louis Toutain INRA Productions Animales, 2011, 24 (2), pp.199-204 Article dans une revue hal-01191161v1
Antibiothérapie : les questions qu'il faut se poser avant toute prescription Aude Ferran,Alain Bousquet‐mélou Pratique Veterinaire, 2011, 46, pp.86-88 Article dans une revue hal-02646601v1
Laparoscopic-assisted colopexy and sterilization in male dogs: short-term results and physiologic consequences Didier H. Mathon,Sophie Palierne,Patricia Meynaud-Collard,Catherine Layssol-Lamour,Alice Dulaurent-Ferriereset al. Veterinary Surgery, 2011, 40 (4), pp.500-508. ⟨10.1111/j.1532-950X.2011.00835.x⟩ Article dans une revue istex hal-02644128v1
Impact of early versus later fluoroquinolone treatment on the clinical; microbiological and resistance outcomes in a mouse-lung model of Pasteurella multocida infection. Aude A Ferran,Pierre-Louis Toutain,Alain Bousquet‐mélou Vet Microbiol, 2011, 148 (2-4), pp.292-7. ⟨10.1016/j.vetmic.2010.09.005⟩ Article dans une revue hal-00523818v1
Emergence of resistant Klebsiella pneumoniae in the intestinal tract during successful treatment of Klebsiella pneumoniae lung infection in rats. Anne-Sylvie Kesteman,Agnès Perrin-Guyomard,Michel Laurentie,Pascal Sanders,Pierre-Louis Toutainet al. Antimicrobial Agents and Chemotherapy, 2010, 54 (7), pp.2960-4. ⟨10.1128/AAC.01612-09⟩ Article dans une revue hal-00517528v1
Species differences in pharmacokinetics and pharmacodynamics. Pierre-Louis Toutain,Aude Ferran,Alain Bousquet‐mélou Handb Exp Pharmacol, 2010, 199, pp.19-48. ⟨10.1007/978-3-642-10324-7_2⟩ Article dans une revue hal-00517529v1
Influence of inoculum size and dosing regimen on the selection of marbofloxacin resistant mutants in experimental rat Klebsiella pneumoniae lung infection Anne-Sylvie Kesteman,Aa Ferran,A Perrin-Guyomard,Michel Laurentie,Pascal Sanderset al. Journal of Veterinary Pharmacology and Therapeutics, 2009, 32 (s1), pp.63-63 Article dans une revue hal-02654001v1
Relatedness of Ampicillin-resistant Escherichia coli strains isolated from pigs during ampicillin treatment Delphine Bibbal,V Dupouy,Nathalie Arpaillange,Mf Prere,Pierre-Louis Toutainet al. Journal of Veterinary Pharmacology and Therapeutics, 2009, 32, pp.138-139 Article dans une revue hal-02656491v1
Impact of marbofloxacin dosing regimen on intestinal flora in a dixenic rat model with Klebsiella pneumoniae lung infection Anne-Sylvie Kesteman,Aa Ferran,A Perrin-Guyomard,Michel Laurentie,Pascal Sanderset al. Journal of Veterinary Pharmacology and Therapeutics, 2009, 32 (s1), pp.150-151 Article dans une revue hal-02656744v1
Relatedness of Escherichia coli strains with different susceptibility phenotypes isolated from swine feces during ampicillin treatment. Delphine Bibbal,Véronique Dupouy-Guiraute,Marie-Françoise Prère,Pierre-Louis Toutain,Alain Bousquet‐mélou Applied and Environmental Microbiology, 2009, 75 (10), pp.2999-3006. ⟨10.1128/AEM.02143-08⟩ Article dans une revue hal-00517533v1
Pharmacokinetic/pharmacodynamic analysis of the influence of inoculum size on the selection of resistance in Escherichia coli by a quinolone in a mouse thigh bacterial infection model. Aude A Ferran,Anne-Sylvie Kesteman,Pierre-Louis Toutain,Alain Bousquet‐mélou Antimicrobial Agents and Chemotherapy, 2009, 53 (8), pp.3384-90. ⟨10.1128/AAC.01347-08⟩ Article dans une revue hal-00517532v1
Influence of inoculum size and marbofloxacin plasma exposure on the amplification of resistant subpopulations of Klebsiella pneumoniae in a rat lung infection model. Anne-Sylvie Kesteman,Aude A Ferran,Agnès Perrin-Guyomard,Michel Laurentie,Pascal Sanderset al. Antimicrobial Agents and Chemotherapy, 2009, 53 (11), pp.4740-8. ⟨10.1128/AAC.00608-09⟩ Article dans une revue hal-00517531v1
A PK/PD analysis of the selection of marbofloxacin resistance in Escherichia coli in a mouse-thigh infection model Aa Ferran,Anne-Sylvie Kesteman,Pierre-Louis Toutain,Alain Bousquet‐mélou Journal of Veterinary Pharmacology and Therapeutics, 2009, 32 (s1), pp.69-70 Article dans une revue hal-02653949v1
Influence of obesity on the pharmacokinetics of anthelmintic macrocyclic lactones in dogs I Bargues,Anne Lespine,Pierre-Louis Toutain,Alain Bousquet‐mélou Journal of Veterinary Pharmacology and Therapeutics, 2009, 32 (s1), pp.161-162 Article dans une revue hal-02654350v1
New antibiotics in orphan food-producing animals: what is the responsibility of a journal regarding good veterinary practice? Pierre-Louis Toutain,Alain Bousquet‐mélou Veterinary Journal, 2009, 179 (2), pp.155-7. ⟨10.1016/j.tvjl.2008.03.022⟩ Article dans une revue istex hal-00517536v1
Les apports et les limites de la clinique et des essais cliniques dans l'évaluation des antibiotiques Pierre-Louis Toutain,Alain Bousquet‐mélou Bulletin des G.T.V., 2008, 43, pp.57-62 Article dans une revue hal-02653542v1
Induction of the carrier state in pigeons infected with Salmonella enterica subspecies enterica serovar typhimurium PT99 by treatment with florfenicol: a matter of pharmacokinetics. Frank Pasmans,Kris Baert,An Martel,Alain Bousquet‐mélou,Ruben Lanckrietet al. Antimicrobial Agents and Chemotherapy, 2008, 52 (3), pp.954-61. ⟨10.1128/AAC.00575-07⟩ Article dans une revue hal-00517567v1
L'antibiothérapie dans les entérites infectieuses néonatales du veau Pierre-Louis Toutain,Alain Bousquet‐mélou Le Nouveau Praticien Vétérinaire. Elevages et Santé, 2008, pp.27-30 Article dans une revue hal-02653320v1
Les bonnes pratiques de l'antibiothérapie chez le cheval Aude Ferran,Alain Bousquet‐mélou,Pierre-Louis Toutain Le Nouveau Praticien Vétérinaire. Equine, 2008, pp.117-121 Article dans une revue hal-02654400v1
Oral absorption of ampicillin: role of paracellular route vs. PepT1 transporter. Guylène Lafforgue,Cécile Arellano,Christelle Vachoux,John Woodley,Claude Philibertet al. Fundamental & Clinical Pharmacology, 2008, 22 (2), pp.189-201. ⟨10.1111/j.1472-8206.2008.00572.x⟩ Article dans une revue istex hal-00517537v1
Pharmacokinetics of eight anticoagulant rodenticides in mice after single oral administration. V. Vandenbroucke,Alain Bousquet‐mélou,Patrick de Backer,Siska Croubels Journal of Veterinary Pharmacology and Therapeutics, 2008, 31 (5), pp.437-45. ⟨10.1111/j.1365-2885.2008.00979.x⟩ Article dans une revue istex hal-00517535v1
AUC/MIC: a PK/PD index for antibiotics with a time dimension or simply a dimensionless scoring factor? Pierre-Louis Toutain,Alain Bousquet‐mélou,Marilyn Martinez Journal of Antimicrobial Chemotherapy, 2007, 60 (6), pp.1185-8. ⟨10.1093/jac/dkm360⟩ Article dans une revue istex hal-00517556v1
Impact of three ampicillin dosage regimens on selection of ampicillin resistance in Enterobacteriaceae and excretion of blaTEM genes in swine feces. Delphine Bibbal,Véronique Dupouy-Guiraute,Jean-Pierre Ferré,Pierre-Louis Toutain,Olivier Fayetet al. Applied and Environmental Microbiology, 2007, 73 (15), pp.4785-90. ⟨10.1128/AEM.00252-07⟩ Article dans une revue hal-00517560v1
Influence of inoculum size on the selection of resistant mutants of Escherichia coli in relation to mutant prevention concentrations of marbofloxacin. Aude Ferran,Véronique Dupouy-Guiraute,Pierre-Louis Toutain,Alain Bousquet‐mélou Antimicrobial Agents and Chemotherapy, 2007, 51 (11), pp.4163-6. ⟨10.1128/AAC.00156-07⟩ Article dans une revue hal-00517559v1
Estimation of absolute oral bioavailability of moxidectin in dogs using a semi-simultaneous method: influence of lipid co-administration. Elodie Lallemand,Anne Lespine,Michel Alvinerie,Alain Bousquet‐mélou,Pierre-Louis Toutain Journal of Veterinary Pharmacology and Therapeutics, 2007, 30 (5), pp.375-80. ⟨10.1111/j.1365-2885.2007.00878.x⟩ Article dans une revue istex hal-00517557v1
Enrofloxacin and marbofloxacin in horses: comparison of pharmacokinetic parameters, use of urinary and metabolite data to estimate first-pass effect and absorbed fraction. Mathieu Peyrou,Alain Bousquet‐mélou,Valérie Laroute,André Vrins,Michèle Y. Doucet Journal of Veterinary Pharmacology and Therapeutics, 2006, 29 (5), pp.337-44. ⟨10.1111/j.1365-2885.2006.00752.x⟩ Article dans une revue istex hal-00517561v1
The adrenocorticotropin stimulation test: contribution of a physiologically based model developed in horse for its interpretation in different pathophysiological situations encountered in man. Alain Bousquet‐mélou,Enrique Formentini,Nicole Picard-Hagen,Laure Delage,Valérie Larouteet al. Endocrinology, 2006, 147 (9), pp.4281-91. ⟨10.1210/en.2005-1161⟩ Article dans une revue hal-00517562v1
Contribution of lymphatic transport to the systemic exposure of orally administered moxidectin in conscious lymph duct-cannulated dogs. Anne Lespine,Guillaume Chanoit,Alain Bousquet‐mélou,Elodie Lallemand,Firas Mohamad Bassissiet al. European Journal of Pharmaceutical Sciences, 2006, 27 (1), pp.37-43. ⟨10.1016/j.ejps.2005.08.003⟩ Article dans une revue istex hal-00517563v1
Pharmacokinetics and pharmacodynamics of a therapeutic dose of unfractionated heparin (200 U/kg) administered subcutaneously or intravenously to healthy dogs. Armelle Diquélou,C. Barbaste,A. M. Gabaig,Cathy Trumel,Nathalie Abella-Bourgeset al. Veterinary Clinical Pathology, 2005, 34 (3), pp.237-42 Article dans une revue hal-00517564v1
Particularité des voies orales et topiques chez les ruminants : conséquences pour les antiparasitaires Pierre-Louis Toutain,Alain Bousquet‐mélou Bulletin des G.T.V., 2005, Hors-série, pp.43-47 Article dans une revue hal-02670330v1
Pharmacokinetics and pharmacodynamics of a therapeutic dose of unfractionated heparin (200 U/kg) administered subcutaneously or intravenously to healthy dogs Armelle Diquélou,Cécile Barbaste,Am Gabaig,Catherine Trumel,Nathalie Abella-Bourgeset al. Veterinary Clinical Pathology, 2005, 34 (3), pp.237-242. ⟨10.1111/j.1939-165x.2005.tb00047.x⟩ Article dans une revue hal-02670873v1
Comment déterminer et optimiser un schéma posologique pour un antibiotique Pierre-Louis Toutain,Alain Bousquet‐mélou Bulletin des G.T.V., 2005, Hors-série, pp.57-62 Article dans une revue hal-02669487v1
Population pharmacokinetics of marbofloxacin in horses: preliminary analysis. Mathieu Peyrou,Michèle Y. Doucet,André Vrins,Didier Concordet,Marc Schneideret al. Journal of Veterinary Pharmacology and Therapeutics, 2004, 27 (5), pp.283-8. ⟨10.1111/j.1365-2885.2004.00591.x⟩ Article dans une revue istex hal-00517574v1
Plasma terminal half-life. Pierre-Louis Toutain,Alain Bousquet‐mélou Journal of Veterinary Pharmacology and Therapeutics, 2004, 27 (6), pp.427-39. ⟨10.1111/j.1365-2885.2004.00600.x⟩ Article dans une revue istex hal-00517570v1
Plasma clearance. Pierre-Louis Toutain,Alain Bousquet‐mélou Journal of Veterinary Pharmacology and Therapeutics, 2004, 27 (6), pp.415-25. ⟨10.1111/j.1365-2885.2004.00605.x⟩ Article dans une revue istex hal-00517571v1
Volumes of distribution. Pierre-Louis Toutain,Alain Bousquet‐mélou Journal of Veterinary Pharmacology and Therapeutics, 2004, 27 (6), pp.441-53. ⟨10.1111/j.1365-2885.2004.00602.x⟩ Article dans une revue istex hal-00517569v1
Endectocide exchanges between grazing cattle after pour-on administration of doramectin, ivermectin and moxidectin. Alain Bousquet‐mélou,Sonia Mercadier,Michel Alvinerie,Pierre-Louis Toutain International Journal for Parasitology, 2004, 34 (11), pp.1299-307. ⟨10.1016/j.ijpara.2004.08.005⟩ Article dans une revue istex hal-00517575v1
Bioavailability and its assessment. Pierre-Louis Toutain,Alain Bousquet‐mélou Journal of Veterinary Pharmacology and Therapeutics, 2004, 27 (6), pp.455-66. ⟨10.1111/j.1365-2885.2004.00604.x⟩ Article dans une revue istex hal-00517568v1
A pharmacokinetic model to document the actual disposition of topical ivermectin in cattle Céline M. Laffont,Alain Bousquet‐mélou,David Bralet,Michel Alvinerie,Johanna Fink-Gremmelset al. Veterinary Research, 2003, 34 (4), pp.445-460. ⟨10.1051/vetres:2003014⟩ Article dans une revue hal-00902759v1
A pharmacokinetic model to document the actual disposition of topical ivermectin in cattle. Céline M. Laffont,Alain Bousquet‐mélou,David Bralet,Michel Alvinerie,Johanna Fink-Gremmelset al. Veterinary Research, 2003, 34 (4), pp.445-60. ⟨10.1051/vetres:2003014⟩ Article dans une revue hal-00517578v1
Antibiothérapie au tarissement Les spécialités disponibles curatives et/ou préventives Alain Bousquet‐mélou Le Point vétérinaire, 2003, Supplément, pp.19-23 Article dans une revue hal-02670292v1
Modelling the loss of metabolic capacities of cultured hepatocytes: application to measurement of Michaelis-Menten kinetic parameters in in vitro systems. Alain Bousquet‐mélou,Céline M. Laffont,Valérie Laroute,Pierre-Louis Toutain Xenobiotica, 2002, 32 (10), pp.895-906. ⟨10.1080/00498250210163261⟩ Article dans une revue hal-00517576v1
Intestinal secretion is a major route for parent ivermectin elimination in the rat. Céline M. Laffont,Pierre-Louis Toutain,Michel Alvinerie,Alain Bousquet‐mélou Drug Metabolism and Disposition, 2002, 30 (6), pp.626-30 Article dans une revue hal-00517587v1
Effects of altered plasma alpha1-acid glycoprotein levels on pharmacokinetics of some basic antibiotics in pigs: simulation analysis. Alain Bousquet‐mélou,Pierre-Louis Toutain Journal of Veterinary Pharmacology and Therapeutics, 2002, 25 (3), pp.239 Article dans une revue hal-00517586v1
The pharmacokinetic-pharmacodynamic approach to a rational dosage regimen for antibiotics. Pierre-Louis Toutain,Jérome R. E. del Castillo,Alain Bousquet‐mélou Research in Veterinary Science, 2002, 73 (2), pp.105-14. ⟨10.1016/S0034-5288(02)00039-5⟩ Article dans une revue istex hal-00517583v1
Free drug fraction vs free drug concentration: a matter of frequent confusion. Pierre-Louis Toutain,Alain Bousquet‐mélou Journal of Veterinary Pharmacology and Therapeutics, 2002, 25 (6), pp.460-3. ⟨10.1046/j.1365-2885.2002.00442.x⟩ Article dans une revue istex hal-00517582v1
Letter to the Editor Alain Bousquet‐mélou,Pierre-Louis Toutain Journal of Veterinary Pharmacology and Therapeutics, 2002, 25 (3), pp.239-239 Article dans une revue hal-02669513v1
Pharmacokinetics of marbofloxacin in horses. Alain Bousquet‐mélou,Sophie Bernard,Marc Schneider,Pierre-Louis Toutain Equine Veterinary Journal, 2002, 34 (4), pp.366-72. ⟨10.2746/042516402776249191⟩ Article dans une revue istex hal-00517584v1
A nonlabeled method to evaluate cortisol production rate by modeling plasma CBG-free cortisol disposition. Nicole Picard-Hagen,Véronique V. Gayrard-Troy,Michel Alvinerie,Hélène Smeyers,Raphael Ricouet al. AJP - Endocrinology and Metabolism, 2001, 281 (5), pp.E946-56. ⟨10.1152/ajpendo.2001.281.5.E946⟩ Article dans une revue hal-00517589v1
Licking behaviour and environmental contamination arising from pour-on ivermectin for cattle. Céline M. Laffont,Michel Alvinerie,Alain Bousquet‐mélou,Pierre-Louis Toutain International Journal for Parasitology, 2001, 31 (14), pp.1687-92 Article dans une revue hal-00517588v1
Relevance of kinetic concepts to interpret a plasma concentration in clinical biochemistry (clearance, production rate, binding, half-life) P.L. Toutain,H.P. Lefebvre,Alain Bousquet‐mélou Revue de Médecine Vétérinaire, 2000, 151 (7), pp.643-648 Article dans une revue hal-02684014v1
Lipolytic effects of beta 1-, beta 2-, and beta 3-adrenergic agonists in white adipose tissue of mammals. Christian Carpéné,Alain Bousquet‐mélou,Jean Galitzky,Max Lafontan,Non Renseigné Annals of the New York Academy of Sciences, 1998, 839, pp.186-9 Article dans une revue hal-00517591v1
Adrenergic regulation of adipocyte metabolism. M. Lafontan,P. Barbe,J. Galitzky,G. Tavernier,D. Langinet al. Human Reproduction, 1997, 12 Suppl 1, pp.6-20 Article dans une revue hal-00517592v1
Evidence for numerous brown adipocytes lacking functional beta 3-adrenoceptors in fat pads from nonhuman primates. N. Viguerie-Bascands,Alain Bousquet‐mélou,J. Galitzky,D. Larrouy,D. Ricquieret al. Journal of Clinical Endocrinology and Metabolism, 1996, 81 (1), pp.368-75 Article dans une revue hal-00517758v1
Control of lipolysis in intra-abdominal fat cells of nonhuman primates: comparison with humans. Alain Bousquet‐mélou,Jean Galitzky,M. Lafontan,M. Berlan Journal of Lipid Research, 1995, 36 (3), pp.451-61 Article dans une revue hal-00517763v1
[Lipid mobilization, physiopathological and pharmacological aspects] M. Berlan,P. Barbe,V. Stich,Jean Galitzky,Alain Bousquet‐mélouet al. Annales d'Endocrinologie = Annals of Endocrinology, 1995, 56 (2), pp.97-100 Article dans une revue hal-00517765v1
Adrenergic receptors and fat cells: differential recruitment by physiological amines and homologous regulation. M. Lafontan,Alain Bousquet‐mélou,J. Galitzky,P. Barbe,C. Carpénéet al. Obesity Research, 1995, 3 Suppl 4 (6), pp.507S-514S Article dans une revue hal-00517759v1
Differential activation of beta 1-, beta 2- and beta 3-adrenoceptors by catecholamines in white and brown adipocytes. Jean Galitzky,C. Carpéné,Alain Bousquet‐mélou,M. Berlan,M. Lafontan Fundamental & Clinical Pharmacology, 1995, 9 (4), pp.324-31 Article dans une revue hal-00517764v1
Desensitization of beta-adrenergic responses in adipocytes involves receptor subtypes and cAMP phosphodiesterase. Alain Bousquet‐mélou,Jean Galitzky,C. M. Moreno,M. Berlan,M. Lafontan European Journal of Pharmacology, 1995, 289 (2), pp.235-47 Article dans une revue hal-00517760v1
Beta-3 adrenoceptor-mediated increase in cutaneous blood flow in the dog. M. Berlan,J. Galitzky,Alain Bousquet‐mélou,M. Lafontan,J. L. Montastruc Journal of Pharmacology and Experimental Therapeutics, 1994, 268 (3), pp.1444-51 Article dans une revue hal-00517771v1
beta-Adrenergic control of lipolysis in primate white fat cells: a comparative study with nonprimate mammals. Alain Bousquet‐mélou,Jean Galitzky,C. Carpéné,M. Lafontan,M. Berlan American Journal of Physiology, 1994, 267 (1 Pt 2), pp.R115-23 Article dans une revue hal-00517768v1
The positive chronotropic effect induced by BRL 37344 and CGP 12177, two beta-3 adrenergic agonists, does not involve cardiac beta adrenoceptors but baroreflex mechanisms. G. Tavernier,J. Galitzky,Alain Bousquet‐mélou,J. L. Montastruc,M. Berlan Journal of Pharmacology and Experimental Therapeutics, 1992, 263 (3), pp.1083-90 Article dans une revue hal-00517774v1
GRF treatment of late pregnant ewes alters maternal and fetal somatotropic axis activity. M. M. Blanchard,C. G. Goodyer,J. Charrier,G. Kann,R. Garcia-Villaret al. American Journal of Physiology, 1991, 260 (4 Pt 1), pp.E575-80 Article dans une revue hal-00517775v1

Communication dans un congrès (68)

Mitigation of antibioresistance dissemination through the comprehensive optimization of sludge treatment Amine Ezzariai,Lucie Sauvadet,Gnaneswaran Jenita,Nathalie Arpaillange,Maialen Barretet al. 5. IWA Specialized International Conference ‘Ecotechnologies for Wastewater Treatment (ecoSTP), university of Milano, Jun 2021, Milano, Italy Communication dans un congrès hal-04166692v1
Exposure evaluation of Fipronil: from pets to fleas Marlène Z. Lacroix,E. Bouhsira,E. Liénard,Catherine Viguié,M. Francet al. 14. International Congress of the European Association for Veterinary Pharmacology and Toxicology, Jun 2018, Wroclaw, Poland. pp.1 Communication dans un congrès hal-02738214v1
Comment assurer l’exposition adéquate d’une population d’agneaux lors de l’administration d’antibiotiques via l’eau de boisson en atelier d’engraissement ovin Béatrice Roques,Marlène Z. Lacroix,Laura Fouzari,Aude Ferran,Didier Concordetet al. 24 E Journées " Rencontres Recherches Ruminants (3R), 2018, Paris, France Communication dans un congrès hal-03275416v1
Pharmacodynamics of ertapenem with and without concurrent use of an immunostimulant using an induced cystitis model in sheep J. Smith,C. Slagel,D. Borts,Aude Ferran,Alain Bousquet‐mélouet al. 14. International Congress of the European Association for Veterinary Pharmacology and Toxicology, Jun 2018, Wroclaw, Poland Communication dans un congrès hal-02733821v1
Assessment of amikacin and vancomycin combination efficacy on two Staphylococcus aureus strains: a comparison between static and dynamic in vitro methods Diane Broussou,F. El Garch,F. Whoerle,P. L. Toutain,Alain Bousquet‐mélouet al. 14. International Congress of the European Association for Veterinary Pharmacology and Toxicology, 2018, Wroclaw, Poland Communication dans un congrès hal-02736593v1
Antibiotic treatments via drinking water in sheep fattening houses: how to ensure an adequate exposure of the treated population? Béatrice Roques,Marlène Z. Lacroix,Laura Fouzari,Aude Ferran,Didier Concordetet al. 14. International Congress of the European Association for Veterinary Pharmacology and Toxicology, Jun 2018, Wroclaw, Poland Communication dans un congrès hal-02734792v1
The EUCAST/VETCAST approach to breakpoint and determination Pierre-Louis Toutain,Ludovic Pelligand,Alain Bousquet‐mélou,Peter Damborg,Aude Ferranet al. 9.th International Conference on Antimicrobial Agents in Veterinary Medicine, Antimicrobial Agents in Veterinary Medicine (AAVM). Rome, ITA., Oct 2018, Rome, Italy Communication dans un congrès hal-02735427v1
KN Precision medicine for the prudent use of veterinary antimicrobials in food producing animals Alain Bousquet‐mélou 14. International Congress of the European Association for Veterinary Pharmacology and Toxicology, Jun 2018, Wroclaw, Poland. pp.1 Communication dans un congrès hal-02734350v1
Veterinary medicine needs new and innovative green antibiotics Pierre-Louis Toutain,Aude Ferran,Alain Bousquet‐mélou,Ludovic Pelligand,Peter Lees Conference on Residues of Veterinary Drugs in Food, EuroResidue VIII., May 2016, Egmond aan Zee, Netherlands Communication dans un congrès hal-01606643v1
Development of an in vitro model for the multiparametric quantification of interactions between Staphylococcus aureus, murine macrophages and a cephalosporin antibiotic Elodie Lallemand,Aude Ferran,C. Zemirline,Pierre-Louis Toutain,S. Boullieret al. Abstracts of the 50th Annual Scientific Meeting of the European Society for Clinical Investigation, Apr 2016, Paris, France. pp.2 Communication dans un congrès hal-02741238v1
Role of the metacommunity in the colonization of rabbit's intestinal tract to fight against antibiotic-resistant bacteria Caroline Achard,Beatrice Gabinaud,Sylvie Combes,Véronique Dupouy-Guiraute,Yuliaxis Ramayo Caldaset al. 16. International Symposium on Microbial Ecology - ISME16, Aug 2016, Montréal, Canada Communication dans un congrès hal-02799866v1
Pharmacodynamic/pharmacokinetic analysis of cephalexin activity on Staphylococcus aureus in a new in vitro model with and without macrophages Elodie Lallemand,Aude Ferran,Claudine Zemirline,Pierre-Louis Toutain,Séverine Boullieret al. 13th. International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT), European Association for Veterinary Pharmacology and Toxicology (EAVPT). FRA., Jul 2015, Nantes, France. pp.176 Communication dans un congrès hal-02742165v1
Etat des lieux de l'antibiorésistance en élevage cunicole français et application du concept d'exclusion compétitive pour limiter la transmission d'un microbiote maternal antibiorésistant Caroline Achard,Véronique Dupouy-Guiraute,Susanna Siviglia,Nathalie Arpaillange,Beatrice Gabinaudet al. 16. Journées de la Recherche Cunicole, Nov 2015, Le Mans, France. 264 p Communication dans un congrès hal-02744277v1
Evaluation of the influence of treatment time and antibiotic dosage regimen on bacterial burden and clinical outcomes in experimentally infected calves with Mannheimia haemolytica Guillaume Lhermie,Aude Ferran,Farid El Garch,Marc Schneider,Frédérique Woerhléet al. 13th. International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT), European Association for Veterinary Pharmacology and Toxicology (EAVPT). FRA., Jul 2015, Nantes, France. pp.176 Communication dans un congrès hal-02742822v1
Impact of a decreased antimicrobial therapy at early stage of spontaneous bovine pneumonia cases on antimicrobial consumption and therapeutic efficacy Guillaume Lhermie,Alain Bousquet‐mélou,Farid El Garch,Henri Seegers,Sébastien Assie 14. International Symposium on Veterinary Epidemiology and Economics (ISVEE), Nov 2015, Merida, Mexico. 670 p Communication dans un congrès hal-02742841v1
The consequences of generic marketing on antibiotic consumption and the spread of antimicrobial resistance: the need for new antibiotics Alain Bousquet‐mélou,Pierre-Louis Toutain 13th International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT), European Association for Veterinary Pharmacology and Toxicology (EAVPT). FRA., Jul 2015, Nantes, France Communication dans un congrès hal-02743077v1
Resistome of pig and rabbit gut microbiota using high-troughput sequencing and qPCR approaches Caroline Achard,Véronique Dupouy-Guiraute,Yuliaxis Ramayo Caldas,Beatrice Gabinaud,Catherine Deniset al. 6. Symposium on Antimicrobial Résistance in Animals and the Environment (ARAE), Jun 2015, Tours, France. 109p Communication dans un congrès hal-01536555v1
Bisphenol A-glucuronide hydrolysis in the ovine fetal compartment prolongs the fetal exposure to Bisphenol A Glenn Gauderat,Nicole Picard-Hagen,Catherine Viguié,Sylvie Puel,Marlène Z. Lacroixet al. 13th International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT), European Association for Veterinary Pharmacology and Toxicology (EAVPT). FRA., Jul 2015, Nantes, France. pp.176 Communication dans un congrès hal-02741104v1
Activity of antimicrobial monotherapy versus combination therapy against staphylococcus aureus biofilm in vitro. Jingjing Liu,Alain Bousquet‐mélou,Pierre-Louis Toutain,Aude A Ferran 7th International Conference on Antimicrobial Agents in Veterinary Medicine, Antimicrobial Agents in Veterinary Medicine (AAVM). Berlin, DEU., Sep 2014, Berlin, Germany Communication dans un congrès hal-02741090v1
Influence of pasteurellaceae species and dose regimen on in vitro activity an in vivo efficacy of a fluoroquinolone treatment Guillaume Lhermie,Aude Ferran,Farid El Garch,Gilles G. Meyer,Alain Bousquet‐mélou 7th International Conférence on Antimicrobial Agents in Veterinary Medicine ( AAVM), Antimicrobial Agents in Veterinary Medicine (AAVM). Berlin, DEU., Sep 2014, Berlin, Germany Communication dans un congrès hal-02742843v1
Les anciens antibiotiques sont-ils meilleurs que les nouveaux pour lutter contre l'antibiorésistance? Quand et comment utiliser les antibiotiques critiques? Pierre-Louis Toutain,Aude Ferran,Elodie Lallemand,Alain Bousquet‐mélou Journées Nationales des GTV, Société Nationale des Groupements Techniques Vétérinaires (SNGTV). Reims, FRA., May 2014, Reims, France Communication dans un congrès hal-02741112v1
Influence of marbofloxacin on the selection of bacterial resistances in the gut microbiota of veal calves. Investigation of a strategy aiming at reducing both selective pressure and resistance selection Mouni Abdelli,Amandine Roques,Véronique Dupouy-Guiraute,Aude Ferran,Pierre-Louis Toutainet al. 7th International Conférence on Antimicrobial Agents in Veterinary Medicine ( AAVM), Antimicrobial Agents in Veterinary Medicine (AAVM). DEU., Sep 2014, Berlin, Germany Communication dans un congrès hal-02742567v1
Antimicrobial resistan ce of shiga toxin gene (stx)-positive and initimin gene (eae)-positive Escherichia coli isolates from wastewaters of an urban wastewater treatment plant (WWTP) collecting slaughterhouse effluents Delphine Bibbal,Véronique Dupouy-Guiraute,Alpha Amadou Diallo,Monique Kérourédan,Nathalie Arpaillangeet al. 3rd ASM Conference on Antimicrobial Resistance in Zoonotic Bacteria and Foodborne Pathogrens in Animals, Humans, and the Environmen, American Society for Microbiology. USA., Jun 2012, Aix-en-Provence, France Communication dans un congrès hal-02746917v1
Early versus later antibiotic treatments of pulmonary infections. A strategy to conciliate control of infectious diseases and reduction of antibiotic consumption Alain Bousquet‐mélou,Aude Ferran,Maleck V. Vasseur,Pierre-Louis Toutain 6th International Conference on Antimicrobial Agents in Veterinary Medicine, Antimicrobial Agents in Veterinary Medicine (AAVM). DEU., Oct 2012, Washington, United States Communication dans un congrès hal-02745067v1
Le concept &quot;One Health&quot; en antibiorésistance et les flux de gènes Benoît Doublet,Alain Bousquet‐mélou,J.Y. Madec Pour des aliments sains : savoir maîtriser les risques en alimentation, Nov 2012, Toulouse, France Communication dans un congrès hal-02748843v1
Emergence et diffusion de résistances aux antibiotiques en lien avec leur usage en élevage. Alain Bousquet‐mélou Salon International de l’Agriculture - « Anti-infectieux en élevage : Recherches et alternatives durables, 2012, Paris, France Communication dans un congrès hal-02802918v1
Pharmacodynamic/pharmacokinetic analysis of marbofloxacin activity in plasma and in intestines of swine Aude Ferran,Delphine Bibbal,Terence Pellet,Michel Laurentie,Mireille Gicquel-Bruneauet al. 12th International Congress of the European Association for Veterinary Pharmacology (EAVPT), Jul 2012, Noordwijkerhout, Netherlands. pp.1-182 Communication dans un congrès hal-02749268v1
Licking behaviour affects the disposition of macrocyclic lactone pour-on formulations in cattle Alain Bousquet‐mélou 12. International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT 2012), Jul 2012, Noordwijkerhout, Netherlands. 182 p Communication dans un congrès hal-02747528v1
Differential activity of veterinary antibiotics on target pathogens versus digestive flora: development of a pharmacodynamic selectivity index for public health perspective Maleck V. Vasseur,Aude Ferran,Pierre-Louis Toutain,Alain Bousquet‐mélou 12th International Congress of the European Association for Veterinary Pharmacology (EAVPT), European Association for Veterinary Pharmacology and Toxicology (EAVPT). FRA., Jul 2012, Noordwijkerhout, Netherlands. pp.1-182 Communication dans un congrès hal-02745409v1
Usage prudent des antibiotiques en médecine vétérinaire - Des traitements précoces à la métaphylaxie Alain Bousquet‐mélou Pfizer - Approche raisonnée de la prévention anti-infectieuse chez les Jeunes Bovins à l'engraissement, Laboratoire Pfizer. Saisissez le nom du laboratoire, du service ou du département., Paris, FRA., Jul 2011, Paris, France Communication dans un congrès hal-02802086v1
Antibiotiques et médicaments génériques Alain Bousquet‐mélou Forum Antibiothérapie, Bayer SAS. Saisissez le nom du laboratoire, du service ou du département., Paris, FRA., May 2011 Communication dans un congrès hal-02802426v1
Prevalence and molecular characterization of CTX- M- producing Escherichia coli isolates from wastewaters of a couple slaughterhouse/wastewater treatment plant Véronique Dupouy-Guiraute,Delphine Bibbal,Nathalie Arpaillange,Hubert Brugère,Eric Oswaldet al. 4. Symposium on Antimicrobial Resistance in Animals and the Environment, Jun 2011, Tours, France Communication dans un congrès hal-01577474v1
Effects of early versus late treatments by marbofloxacin in a mouse-model of Pasteurella multocida pulmonary infection Aude Ferran,Pierre-Louis Toutain,Alain Bousquet‐mélou 4.Symposium on Antimicrobial Resistance in Animals and the Environment, Jun 2011, Tours, France. pp.50 Communication dans un congrès hal-01191171v1
Impact d'une antibiothérapie précoce sur l'efficacité de la marbofloxacine lors d'infection pulmonaire expérimentale à Pasteurella multocida Aude Ferran,Pierre-Louis Toutain,Alain Bousquet‐mélou Journéés d'Animation Scientifique du Département Santé Animale, Institut National de Recherche Agronomique (INRA). UMR Toxicologie Alimentaire (1331)., May 2011, Fréjus, France Communication dans un congrès hal-01191170v1
Vite, fort, longtemps, est-ce toujours d'actualité ? Aude Ferran,Pierre-Louis Toutain,Alain Bousquet‐mélou Journées Nationales des GTV, May 2010, Lille, France Communication dans un congrès hal-02754663v1
Quelle voie choisir? Alain Bousquet‐mélou Journées Nationales des GTV, May 2010, Lille, France Communication dans un congrès hal-02753190v1
How biotic and abiotic stress affect growth and secondary metabolism in Mediterranean forest dynamic: a comparative case study of a pioneer (Pinus halepensis Mill) and a late successional species (Quercus pubescens Willd) Yogan Monnier,B. Vila,Alain Bousquet‐mélou,Bernard Prévosto,C. Fernandez 4th SFB 607 Symposium, International Conference on Mechanisms of growth, competition and stress defense in plants, Freising, DEU, 1-3 March 2010, Mar 2010, Freising, Germany. pp.1 Communication dans un congrès hal-02596036v1
La détermination d'un schéma thérapeutique pour un antibiotique Alain Bousquet‐mélou,Aude Ferran,Pierre-Louis Toutain Journées Nationales des GTV, May 2010, Lille, France Communication dans un congrès hal-02754187v1
Impact of marbofloxacin dosing regimen on intestinal flora in a dixenic rat model with Klebsiella pneumoniae lung infection As Kesteman,Aa Ferran,A Perrin-Guyomard,Michel Laurentie,Pascal Sanderset al. 11th International congress of the European Association for Veterinary Pharmacology and Toxicology, 2009, Leipzig, Germany Communication dans un congrès hal-02752387v1
A PK/PD analysis of the selection of marbofloxacin resistance in Escherichia coli in a mouse-thigh infection model Aa Ferran,As Kesteman,Pierre-Louis Toutain,Alain Bousquet‐mélou 11th International congress of the European Association for Veterinary Pharmacology and Toxicology, 2009, Leipzig, Germany Communication dans un congrès hal-02751289v1
Comment les stress biotiques et abiotiques affectent la croissance et le métabolisme secondaire dans la dynamique successionnelle méditerranéenne : étude comparative d'une espèce pionnière (Pinus halepensis Mill.) et d'une espèce de fin de succession (Quercus pubescens Willd.) Yogan Monnier,B. Vila,Alain Bousquet‐mélou,S. Greff,N. Wisniewskiet al. 6ème réunion du GDR Écologie Chimique, Marseille, 27-28 octobre 2009, Oct 2009, Marseille, France. pp.1 Communication dans un congrès hal-02596034v1
Influence of inoculum size and dosing regimen on the selection of marbofloxacin resistant mutants in experimental rat Klebsiella pneumoniae lung infection As Kesteman,Aa Ferran,A Perrin-Guyomard,Michel Laurentie,Pascal Sanderset al. 11th International congress of the European Association for Veterinary Pharmacology and Toxicology, 2009, Leipzig, Germany Communication dans un congrès hal-02751484v1
Influence of obesity on the pharmacokinetics of anthelmintic macrocyclic lactones in dogs I Bargues,Anne Lespine,Pierre-Louis Toutain,Alain Bousquet‐mélou 11th International congress of the European Association for Veterinary Pharmacology and Toxicology, 2009, Leipzig, Germany Communication dans un congrès hal-02752015v1
Relatedness of Ampicillin-resistant Escherichia coli strains isolated from pigs during ampicillin treatment Delphine Bibbal,V Dupouy,Nathalie Arpaillange,Mf Prere,Pierre-Louis Toutainet al. 11th International congress of the European Association for Veterinary Pharmacology and Toxicology, 2009, Leipzig, Germany Communication dans un congrès hal-02754492v1
Relatedness of ampicillin resistant Escherichia coli strains isolated from swine feces during ampicillin treatment Delphine Bibbal,V Dupouy,Mf Prere,Pierre-Louis Toutain,Alain Bousquet‐mélou 3rd Symposium on Antimicrobial Resistance in Animals and the Environment, 2009, Tours, France. pp.Inconnu Communication dans un congrès hal-02817938v1
Impact d'une fluoroquinolone sur la flore pathogène et la flore commensale intestinale dans un modèle d'infection pulmonaire par Klebsiella pneumoniae chez le rat dixénique As Kesteman,Aa Ferran,A Perrin-Guyomard,Michel Laurentie,Pascal Sanderset al. Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu Communication dans un congrès hal-02822116v1
Effects of inoculum size on the selection of resistance in Escherichia coli by marbofloxacin in an in vitro pharmacodynamic model and in a mouse-thigh infection model Aude Ferran,As Kesteman,Pierre-Louis Toutain,Alain Bousquet‐mélou 4th International Conference on Antimicrobial Agents in Veterinary Medicine, 2008, Prague, Czech Republic. pp.Inconnu Communication dans un congrès hal-02816763v1
Relatedness of ampicillin resistant Escherichia coli strains isolated from pigs during ampicillin treatment Delphine Bibbal,V Dupouy,Mf Prere,Pierre-Louis Toutain,Alain Bousquet‐mélou 4th International Conference on Antimicrobial Agents in Veterinary Medicine, 2008, Prague, Czech Republic. pp.Inconnu Communication dans un congrès hal-02816620v1
Influence of inoculum size on the selection of marbofloxacin resistant mutants in experimental rat Klebsiella pneumoniae lung infection As Kesteman,A Perin-Guyomard,Michel Laurentie,Alain Bousquet‐mélou,Pierre-Louis Toutain 4th International Conference on Antimicrobial Agents in Veterinary Medicine, 2008, Prague, Czech Republic. pp.Inconnu Communication dans un congrès hal-02820035v1
Effects of inoculum size on the selection of marbofloxacin resistant mutants in experimental rat klebsiella pneumoniae lung infection As Kesteman,Aude Ferran,A Perrin-Guyomard,Michel Laurentie,Pierre-Louis Toutainet al. 4th International Conference on Antimicrobial Agents in Veterinary Medicine, 2008, Prague, Czech Republic. pp.Inconnu Communication dans un congrès hal-02811562v1
Influence of inoculum size on the selection of marbofloxacin resistant mutants in experimental rat Klebsiella pneumoniae lung infection As Kesteman,Aude Ferran,Pierre-Louis Toutain,Alain Bousquet‐mélou 2nd Symposium on Antimicrobial Resistance in Animals and the Environment, 2007, Tours, France. pp.Inconnu Communication dans un congrès hal-02814585v1
How antibiotic dosage regimens based on PK-PD concepts may be an important contribution to the resistance problem Pierre-Louis Toutain,Alain Bousquet‐mélou 24th World Buiatrics Congress, 2006, Nice, France Communication dans un congrès hal-02750614v1
Impact of ampicillin administration on blaTEM genes excretion in swine stool Delphine Bibbal,Alain Bousquet‐mélou,Véronique Dupouy-Guiraute,Jean-Pierre Ferré,Valérie Larouteet al. 3rd International Conference on Antimicrobial Agents in Veterinary Medicine (AAVM), May 2006, Orlando, United States Communication dans un congrès hal-02752014v1
Impact of ampicillin administration on excretion of blaTEM genes in swine feces Delphine Bibbal,Alain Bousquet‐mélou,V Dupouy,Mf Prere,O Fayetet al. 10th International Congress of the European Association for Veterinary Pharmacology and Toxicology, 2006, Turin, Italy. pp.Inconnu Communication dans un congrès hal-02822925v1
Propriétés pharmacocinétiques/pharmacodynamiques de la céfovécine : perspective du pharmacologue Alain Bousquet‐mélou Congrès AFVAC, 2006, Bordeaux, France. pp.Inconnu Communication dans un congrès hal-02811806v1
Pharmacologie : du nouveau-né à l'adulte Alain Bousquet‐mélou Journées Nationales des Groupements Techniques Vétérinaires (GTV), 2006, Dijon, France Communication dans un congrès hal-02750991v1
Quantification of blaTEM genes in swine stool by real-time PCR V Dupouy,Delphine Bibbal,Alain Bousquet‐mélou,Mf Prere,O Fayetet al. 3rd International Conference on Antimicrobial Agents in Veterinary Medicine (AAVM), 2006, Orlando, United States Communication dans un congrès hal-02751609v1
Evolution de la résistance aux antibiotiques des E coli de la flore fécale au cours d'un traitement à l'ampicilline : étude quantitative voie orale versus voie intramusculaire chez 12 porcelets Delphine Bibbal,D Fajadet,V Dupouy,Alain Bousquet‐mélou,Pierre-Louis Toutainet al. 25e Réunion Interdisciplinaire de Chimiothérapie Anti-Infectieuse, 2005, Paris, France. pp.Inconnu Communication dans un congrès hal-02828300v1
Intestinal lymphatic transport of moxidectin in conscious lymph duct-cannulated dogs Anne Lespine,G Chanoit,Alain Bousquet‐mélou,Elodie Lallemand,F Bassissiet al. EUFEPS Conferences 3rd World Conference on Drug Absorption Transport and delivery, 2004, Barcelona, Spain. pp.Inconnu Communication dans un congrès hal-02827582v1
Population pharmacokinetics of marbofloxacin in horses M Peyrou,My Doucet,A Vrins,M Schneider,Didier Concordetet al. 2nd International Conference on Antimicrobial Agents in Veterinary Medicine, 2004, Ottawa, Canada. pp.Inconnu Communication dans un congrès hal-02825659v1
Ecotoxicological bioassay on ivermectin with the MI bioindicator system: changes in the structure of nematode communities of cattle dung G Gauthier,C Gers,M Alvinerie,Alain Bousquet‐mélou 14th International Colloquium on Soil Zoology and Ecology, 2004, Rouen, France. pp.Inconnu Communication dans un congrès hal-02826658v1
Pharmacokinetics of an oral commercial formulation of marbofloxacin in horses M Peyrou,My Doucet,A Vrins,Valérie Laroute,Alain Bousquet‐mélou 43rd Annual Congress of the British Equine Veterinary Association, 2004, Birmingham, United Kingdom. pp.Inconnu Communication dans un congrès hal-02825372v1
Comparative evaluation of P-glycoprotein activity in horses, pigs, cattle, sheep, goats and rats using a lymphocyte-based ex vivo model C Laffont,G de Vrieze,Roeland Marinus Maas,Alain Bousquet‐mélou,J Fink Gremmels 9th International Congress of the European Association for Veterinary Pharmacology and Toxicology, 2003, Lisbon, Portugal Communication dans un congrès hal-02760354v1
Pharmacokinetics in drug development: beyond single models Pierre-Louis Toutain,Alain Bousquet‐mélou 13th Biennial Symposium of the American Academy of Veterinary Pharmacology and Therapeutics, 2003, Charlotte, United States Communication dans un congrès hal-02758750v1
Drug transfer between grazing cattle after topical administration of doramectin, ivermectin and moxidectin Alain Bousquet‐mélou,S. Mercadier,Nadine Gautier,M. Alvinerie,Pierre-Louis Toutain 9. International Congress of the European Association for Veterinary Pharmacology and Toxicology, European Association for Veterinary Pharmacology and Toxicology (EAVPT). FRA., Jul 2003, Lisbonne, Portugal. 307 p., ⟨10.1046/j.1365-2885.25.s1.1.x⟩ Communication dans un congrès istex hal-02762208v1
Population pharmacokinetics of marbofloxacin in horses Preliminary results of mixed-effect modelling Alain Bousquet‐mélou,P Bourdaud'Hui,Didier Concordet,C Tetot,Y Tamzaliet al. 9th International Congress of the European Association for Veterinary Pharmacology and Toxicology, 2003, Lisbon, Portugal. pp.Inconnu Communication dans un congrès hal-02830489v1
Putative prediction of macrocyclic lactones in vivo-disposition using an original pharmacological parameter [Vp50] obtained from transport experiments in P-glycoprotein-expressing cells Alain Roulet,Alain Bousquet‐mélou,Didier Concordet,Jacques Dupuy,Anne Lespineet al. 19th International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP), 2003, New Orleans, United States. pp.Inconnu Communication dans un congrès hal-02829726v1
Relevance of kinetic concepts to interpret a plasma concentration in clinical biochemistry (clearance, production rate, binding, half-life) P.L. Toutain,H.P. Lefebvre,Alain Bousquet‐mélou 9. Congrès Société Internationale de Biochimie Clinique Animale, Jul 2000, Toulouse, France Communication dans un congrès hal-02835244v1

Poster de conférence (15)

Repeated exposure of Escherichia coli to high ciprofloxacin concentrations selects gyrB mutants that show fluoroquinolone-specific hyperpersistence Aurore Perault,Catherine Turlan,Nathalie Eynard,Quentin Vallé,Alain Bousquet-Melouet al. European Congress of Clinical Microbiology & Infection Diseases (ECCMID), Apr 2022, Lisbon, Portugal. Front Microbiol ., 13, pp.908296, 2022, ⟨10.3389/fmicb.2022.908296⟩ Poster de conférence hal-04955164v1
Original use of a hollow-fiber infection model to investigate a 5-days antibiotic combination against Staphylococcus aureus biofilm Diane Broussou,Marlène Z. Lacroix,P. L. Toutain,F. Woehrle,F. E. Garchet al. 14. International Congress of the European Association for Veterinary Pharmacology and Toxicology, Jun 2018, Wroclaw, Poland. Wiley-Blackwell, Journal of Veterinary Pharmacology and Therapeutics, 41, pp.1, 2018, Special Issue: 14th International Congress of the European Association for Veterinary Pharmacology and Toxicology Poster de conférence hal-02736590v1
Efficacy, effectiveness and efficiency of an alternative treatment protocol of bovine respiratory disease with reduced amount of antimicrobials Guillaume Lhermie,Alain Bousquet‐mélou,Gilles G. Meyer,Henri Seegers,Sébastien Assie 29. World Buiatrics Congress (WBC), Jul 2016, Dublin, Ireland. 728 p., 2016, World Buiatrics Congress (WBC) Poster de conférence hal-02742845v1
Impact of a cephalosporin treatment on the selection and transfer of blacTX-M résistance gene in pig intestine Véronique Dupouy-Guiraute,Nathalie Arpaillange,Edwige Tapie,Vona Dimbimanana,Alain Bousquet‐mélou 6th Symposium on Antimicrobial Résistance in Animals and the Environment (ARAE), Jun 2015, Tours, France. , 2015 Poster de conférence hal-02797320v1
Impact of early versus later beta-lactam treatments on clinical and microbiological outcomes in an original mouse model of airborne &lt;em&gt;Pasteurella multocida&lt;/em&gt; lung infection Maleck V. Vasseur,Aude Ferran,Pierre-Louis Toutain,Alain Bousquet‐mélou 12. International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT 2012), Jul 2012, Noordwijkerhout, Netherlands. Wiley-Blackwell, Journal of Veterinary Pharmacology and Therapeutics, 35 (Suppl. 3), 182 p., 2012, Abstracts of the 12th International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT 2012) Poster de conférence hal-02747497v1
Etude d'un effet inoculum sur l'activité bactéricide de deux bêta-lactamines visà vis de Pasteurella multocida et Escherichia coli Maleck V. Vasseur,Aude Ferran,Pierre-Louis Toutain,Alain Bousquet‐mélou Journées d'Animation scientifiques du Départment de Santé Animale, May 2011, Fréjus, France. pp.1, 2011 Poster de conférence hal-01191176v1
Influence de la taille de l'inoculum bactérien sur la sélection de bactéries résistantes lors d'exposition in vitro et in vivo à la marbofloxacine Aude Ferran,As Kesteman,Pierre-Louis Toutain,Alain Bousquet‐mélou Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu, 2009 Poster de conférence hal-02816105v1
Antimicrobial resistance in Escherichia coli strains carrying virulence genes isolated in wastewater of slaughterhouses in France Delphine Bibbal,Estelle Loukiadis,Monique Kérourédan,Nathalie Arpaillange,V Dupouyet al. 3rd Symposium on Antimicrobial Resistance in Animals and the Environment, 2009, Tours, France. pp.Inconnu, 2009 Poster de conférence hal-02823666v1
A PK/PD analysis of the selection of resistance to marbofloxacin in Escherichia coli in a mouse-thigh infection model Aude Ferran,As Kesteman,Pierre-Louis Toutain,Alain Bousquet‐mélou 3rd Symposium on Antimicrobial Resistance in Animals and the Environment, 2009, Tours, France. pp.Inconnu, 2009 Poster de conférence hal-02815199v1
Caractérisation de l'impact des beta-lactamines sur l'émergence de bactéries résistantes dans la flore fécale chez le porc Delphine Bibbal,V Dupouy,Nathalie Arpaillange,Mf Prere,Pierre-Louis Toutainet al. Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu, 2009 Poster de conférence hal-02822573v1
Influence of inoculum size and dosing regimen on the selection of marbofloxacin resistant mutants in experimental Klebsiella pneumonia lung infection in rats As Kesteman,Aude Ferran,A Perrin-Guyomard,Michel Laurentie,Pascal Sanderset al. 3rd Symposium on Antimicrobial Resistance in Animals and the Environment, 2009, Tours, France. pp.Inconnu, 2009 Poster de conférence hal-02815427v1
Analysis of antimicrobial resistance transfer by conjugation from Escherichia coli strains selected by ampicillin treatment in pig feces V Dupouy,Delphine Bibbal,Nathalie Arpaillange,Mf Prere,Pierre-Louis Toutainet al. 3rd Symposium on Antimicrobial Resistance in Animals and the Environment, 2009, Tours, France. pp.Inconnu, 2009 Poster de conférence hal-02819607v1
Effet de la taille de l'inoculum bactérien sur la sélection de mutants résistants lors d'exposition in vitro d'Escherichia coli à la marbofloxacine Aude Ferran,V Dupouy,Pierre-Louis Toutain,Alain Bousquet‐mélou Journées d’Animation Scientifique du Département de Santé Animale, 2007, Tours, France. pp.Inconnu, 2007 Poster de conférence hal-02815554v1
Impact de l'administration d'ampicilline sur l'excrétion fécale de gènes blaTEM chez le porc Delphine Bibbal,V Dupouy,Jp Ferre,Pierre-Louis Toutain,Mf Prereet al. Journées d’Animation Scientifique du Département de Santé Animale, 2007, Tours, France. pp.Inconnu, 2007 Poster de conférence hal-02816203v1
Putative prediction of macrocyclic lactones in vivo-disposition using an original pharmacological parameter (Vp50) obtained from transport experiments in P-glycoprotein-expressing cells Alain Roulet,Alain Bousquet‐mélou,Didier Concordet,Jacques Dupuy,Anne Lespineet al. 19th International Conference of the World Association for the Advancement of Veterinary Parasitology, 2003, New Orleans, United States. pp.Inconnu, 2003 Poster de conférence hal-02829746v1

Proceedings/Recueil des communications (4)

P17 | In vitro evaluation of the activity of antibiotics against &lt;i&gt;Rhodococcus equi&lt;/i&gt; at pH and concentrations representative of intracellular conditions Aude A. Ferran,Ophelie Gourbeyre,Charline Philibert,Elodie A Lallemand,Alain Bousquet-Mélou 15th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Jul 2023, Bruges, Belgium. Journal of Veterinary Pharmacology and Therapeutics, 46 (S1), pp.93-93, 2023, ⟨10.1111/jvp.13296⟩ Proceedings/Recueil des communications hal-04352568v1
I25 | Reassessment of class D antimicrobials of the AMEG classification: What data needs to be generated for optimal use of old antibiotics? Aude A. Ferran,Alain Bousquet-Mélou 15th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Journal of Veterinary Pharmacology and Therapeutics, 46 (S1), pp.18-19, 2023, ⟨10.1111/jvp.13155⟩ Proceedings/Recueil des communications hal-04352497v1
O73 | Determination of the pharmacokinetic parameters of 4 formulations of penicillin G in order to optimize the first‐line antibiotic treatment in horses Elodie A Lallemand,Alain Bousquet-Mélou,Laura Chapuis,Aude A. Ferran,Taisuke Kurodaet al. 15th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Jul 2023, Bruges, Belgium. Journal of Veterinary Pharmacology and Therapeutics, 46 (S1), pp.64-64, 2023, ⟨10.1111/jvp.13239⟩ Proceedings/Recueil des communications hal-04352514v1
O86 | Combination of antibiotic and bacteriophages to prevent the selection of resistant &lt;i&gt;Pseudomonas aeruginosa&lt;/i&gt; Aude A. Ferran,Marlène Lacroix,Ophelie Gourbeyre,Alicia Huesca,Laurent Debarbieuxet al. 15th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Journal of Veterinary Pharmacology and Therapeutics, 46 (S1), pp.70-71, 2023, ⟨10.1111/jvp.13252⟩ Proceedings/Recueil des communications hal-04352521v1

Chapitre d'ouvrage (1)

Species differences in pharmacokinetics and pharmacodynamics Pierre-Louis Toutain,Aude Ferran,Alain Bousquet‐mélou Comparative and veterinary pharmacology, 199, Springer-Verlag, 2010, Handbook of Experimental Pharmacology, 978-3-642-10323-0. ⟨10.1007/978-3-642-10324-7_2⟩ Chapitre d'ouvrage hal-02824844v1

Autre publication scientifique (3)

Dossier de presse INRA 2017 : microbiote, la révolution intestinale Joël Dore,Dusko Ehrlich,Véronique Monnet,Emmanuelle Le Chatelier,Marianne de Paepeet al. 2017 Autre publication scientifique hal-01605701v1
Oral absorption of ampicillin: role of paracellular route vs. PepT1 transporter Guylène Lafforgue,Cécile Arellano,Christelle Vachoux,John Woodley,Claude Philibertet al. 2008, pp.189-201. ⟨10.1111/j.1472-8206.2008.00572.x⟩ Autre publication scientifique istex hal-04938500v1
Impact de différents types de travaux sylvicoles et de la gestion des rémanents sur la régénération et la végétation au sol d'un peuplement de pin d'Alep Bernard Prévosto,C. Ripert,Alain Bousquet‐mélou Les rémanents en foresterie et agriculture, chapitre 21, par Dodelin, B. et Eynard Machet, R, et Athanaze, P. et André, J., 2007, pp.169-176 Autre publication scientifique hal-02590279v1

Rapport (4)

Méthodologie de révision des posologies d'antibiotiques anciens Alain Bousquet‐mélou,Philippe Berny,Bertrand Faroult,Aude Ferran,Christophe Hugnetet al. [0] 2017 Rapport (rapport d’expertise collective) hal-02788953v1
Rôles, impacts et services issus des élevages en Europe. Rapport final Bertrand Dumont,Pierre Dupraz,Joël Aubin,Miroslav Batka,Diane Beldameet al. [0] Ministère de l'Agriculture, de l'Agroalimentaire et de la Forêt. 2016, 1032 p Rapport (rapport d’expertise collective) hal-01608700v1
Risques d’émergence d’antibiorésistances liés aux modes d’utilisation des antibiotiques dans le domaine de la santé animale Jean-François Guillot,Jacqueline Bastien,Joel Bertin,Alain Bousquet-Mélou,Mireille Gicquel-Bruneauet al. [0] Saisine n ° 2011-SA-0071, Anses. 2014, 240 p Rapport (rapport de recherche) anses-01955006v1
Evaluation des risques d’émergence d’antibiorésistances liés aux modes d’utilisation des antibiotiques dans le domaine de la santé animale Jean-François Guillot,Jacqueline Bastien,Joel Bertin,Alain Bousquet‐mélou,Mireille Bruneauet al. [Technical Report] Anses. 2014 Rapport (rapport technique) hal-01590019v1