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Alejandro Buschiazzo

Group Leader
Current affiliations
  • 519593

Research domains

Cristallography Biochemistry [q-bio.BM] Bacteriology


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Diving into the complexity of the spirochetal endoflagellum

Fabiana San Martin , Lenka Fule , Gregorio Iraola , Alejandro Buschiazzo , Mathieu Picardeau
Trends in Microbiology, 2023, 31 (3), pp.294-307. ⟨10.1016/j.tim.2022.09.010⟩
Journal articles pasteur-04117804v1

An allosteric switch ensures efficient unidirectional information transmission by the histidine kinase DesK from Bacillus subtilis

Sofía Lima , Juan Blanco , Federico Olivieri , Juan Imelio , Marcos Nieves
Science Signaling, 2023, 16 (769), pp.eabo7588. ⟨10.1126/scisignal.abo7588⟩
Journal articles pasteur-04117648v1

Structural features of sensory two component systems: a synthetic biology perspective

Marcos Nieves , Alejandro Buschiazzo , Felipe Trajtenberg
Biochemical Journal, 2023, 480 (2), pp.127-140. ⟨10.1042/BCJ20210798⟩
Journal articles pasteur-04117794v1
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Listeria innocua isolated from diseased ruminants harbour minor virulence genes of L. monocytogenes

Carolina Matto , Bruno d'Alessandro , María Inés Mota , Valeria Braga , Alejandro Buschiazzo
Veterinary Medicine and Science, 2022, 8 (2), pp.735-740. ⟨10.1002/vms3.710⟩
Journal articles hal-04117822v1
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Horizontal transfer of the rfb cluster in Leptospira is a genetic determinant of serovar identity

Cecilia Nieves , Antony Vincent , Leticia Zarantonelli , Mathieu Picardeau , Frédéric Veyrier
Life Science Alliance, 2022, 6 (2), pp.e202201480. ⟨10.26508/lsa.202201480⟩
Journal articles pasteur-04117799v1
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3D cryo-EM imaging of bacterial flagella: Novel structural and mechanistic insights into cell motility

Sonia Mondino , Fabiana San Martin , Alejandro Buschiazzo
Journal of Biological Chemistry, 2022, 298 (7), pp.102105. ⟨10.1016/j.jbc.2022.102105⟩
Journal articles pasteur-04117813v1

Allostery and protein plasticity: the keystones for bacterial signaling and regulation

J. Imelio , F. Trajtenberg , Alejandro Buschiazzo
Biophysical Reviews, 2021, 13 (6), pp.943-953. ⟨10.1007/s12551-021-00892-9⟩
Journal articles pasteur-04117817v1

Role of the major determinant of polar flagellation FlhG in the endoflagella‐containing spirochete Leptospira

Lenka Fule , Ruben Halifa , Celia Fontana , Odile Sismeiro , Rachel Legendre
Molecular Microbiology, 2021, ⟨10.1111/mmi.14831⟩
Journal articles pasteur-03411258v1

The crystal structure of yeast regulatory subunit reveals key evolutionary insights into Protein Kinase A oligomerization

Nicolás González Bardeci , Enzo Tofolón , Felipe Trajtenberg , Julio Caramelo , Nicole Larrieux
Journal of Structural Biology, 2021, 213 (2), pp.107732. ⟨10.1016/j.jsb.2021.107732⟩
Journal articles pasteur-03246652v1

AID overexpression leads to aggressive murine CLL and non-Ig mutations that mirror human neoplasms.

Pablo Elías Morande , Xiao-Jie Yan , Julieta Haydee Sepulveda-Yanez , Noé Seija , Maria Elena Marquez
Journal articles pasteur-03246646v1
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Causes of abortion in dairy cows in Uruguay

Melissa Macías-Rioseco , Caroline Silveira , Martin Fraga , Laura Casaux , Andrés Cabrera
Pesquisa Veterinária Brasileira, 2020, 40 (5), pp.325-332. ⟨10.1590/1678-5150-PVB-6550⟩
Journal articles pasteur-03246634v1
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Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine

Julia Lara , Lautaro Diacovich , Felipe Trajtenberg , Nicole Larrieux , Emilio L. Malchiodi
Nature Communications, 2020, 11 (1), pp.3703. ⟨10.1038/s41467-020-17504-x⟩
Journal articles pasteur-03246643v1
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An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete

Kimberley H Gibson , Felipe Trajtenberg , Elsio A. Jr Wunder , Megan R Brady , Fabiana San Martin
Journal articles pasteur-02549761v1
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Draft Genome Sequences of 40 Pathogenic Leptospira Strains Isolated from Cattle in Uruguay

Cecilia Nieves , Ignacio Ferrés , Florencia Díaz-Viraqué , Alejandro Buschiazzo , Leticia Zarantonelli
Microbiology Resource Announcements, 2019, 8 (47), pp.e00893-19. ⟨10.1128/MRA.00893-19⟩
Journal articles pasteur-02554324v1

Two-Component Sensing and Regulation: How Do Histidine Kinases Talk with Response Regulators at the Molecular Level?

Alejandro Buschiazzo , Felipe Trajtenberg
Annual Review of Microbiology, 2019, 73, pp.507-528. ⟨10.1146/annurev-micro-091018-054627⟩
Journal articles pasteur-02554319v1
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Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation

Cecilia Ortíz , Horacio Botti , Alejandro Buschiazzo , Marcelo Comini
Journal of Molecular Biology, 2019, 431 (11), pp.2143-2162. ⟨10.1016/j.jmb.2019.03.023⟩
Journal articles pasteur-02554318v1

Molecular adaptations of NADP-malic enzyme for its function in C4 photosynthesis in grasses

Clarisa Alvarez , Anastasiia Bovdilova , Astrid Höppner , Christian-Claus Wolff , Mariana Saigo
Nature Plants, 2019, 5 (7), pp.755-765. ⟨10.1038/s41477-019-0451-7⟩
Journal articles pasteur-02554321v1

Conformational plasticity of the response regulator CpxR, a key player in Gammaproteobacteria virulence and drug-resistance

Ariel E Mechaly , Ahmed Haouz , Nathalie Sassoon , Alejandro Buschiazzo , Jean-Michel Betton
Journal of Structural Biology, 2018, 204 (2), pp.165-171. ⟨10.1016/j.jsb.2018.08.001⟩
Journal articles hal-02322059v1
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Lvr, a Signaling System That Controls Global Gene Regulation and Virulence in Pathogenic Leptospira

Haritha Adhikarla , Elsio A. Jr Wunder , Ariel E Mechaly , Sameet Mehta , Zheng Wang
Frontiers in Cellular and Infection Microbiology, 2018, 8, pp.45. ⟨10.3389/fcimb.2018.00045⟩
Journal articles pasteur-02100138v1
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Isolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis

Leticia Zarantonelli , Alejandra Suanes , Paulina Meny , Florencia Buroni , Cecilia Nieves
PLoS Neglected Tropical Diseases, 2018, 12 (9), pp.e0006694. ⟨10.1371/journal.pntd.0006694⟩
Journal articles pasteur-01881268v1

The crystal structure of the malic enzyme from Candidatus Phytoplasma reveals the minimal structural determinants for a malic enzyme

C. Alvarez , F. Trajtenberg , N. Larrieux , M. Saigo , A. Golic
Acta crystallographica Section D : Structural biology [1993-..], 2018, 74 (4), pp.332-340. ⟨10.1107/S2059798318002759⟩
Journal articles pasteur-02554314v1
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FcpB Is a Surface Filament Protein of the Endoflagellum Required for the Motility of the Spirochete Leptospira

Elsio A. Jr Wunder , Leyla Slamti , David N Suwondo , Kimberley H Gibson , Zhiguo Shang
Frontiers in Cellular and Infection Microbiology, 2018, 8, pp.130. ⟨10.3389/fcimb.2018.00130⟩
Journal articles pasteur-02100036v1
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SIMBAD: a sequence-independent molecular-replacement pipeline

Adam J Simpkin , Felix Simkovic , Jens Thomas , Martin Savko , Andrey Lebedev
Acta crystallographica Section D : Structural biology [1993-..], 2018, 74 (7), pp.595-605. ⟨10.1107/S2059798318005752⟩
Journal articles pasteur-02554316v1

Structural Coupling between Autokinase and Phosphotransferase Reactions in a Bacterial Histidine Kinase

Ariel E Mechaly , Silvia Soto Diaz , Nathalie Sassoon , Alejandro Buschiazzo , Jean-Michel Betton
Structure, 2017, 25 (6), pp.939-944.e3. ⟨10.1016/j.str.2017.04.011⟩
Journal articles pasteur-02554313v1
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Snapshots of the Signaling Complex DesK:DesR in Different Functional States Using Rational Mutagenesis and X-ray Crystallography

Juan A Imelio , Nicole Larrieux , Ariel E Mechaly , Felipe Trajtenberg , Alejandro Buschiazzo
Bio-protocol , 2017, 7 (16), ⟨10.21769/BioProtoc.2510⟩
Journal articles pasteur-02872312v1

Crystallization of FcpA from Leptospira, a novel flagellar protein that is essential for pathogenesis

Fabiana San Martin , Nicole Larrieux , Ariel E Mechaly , Elsio A. Jr Wunder , Albert I Ko
Acta crystallographica Section F : Structural biology communications [2014-..], 2017, 73 (3), pp.123 - 129. ⟨10.1107/S2053230X17002096⟩
Journal articles pasteur-02554311v1
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Crystal Structure of the Metallo-β-Lactamase GOB in the Periplasmic Dizinc Form Reveals an Unusual Metal Site.

Jorgelina Morán-Barrio , María-Natalia Lisa , Nicole Larrieux , Salvador I Drusin , Alejandro M Viale
Antimicrobial Agents and Chemotherapy, 2016, 60 (10), pp.6013-22. ⟨10.1128/aac.01067-16⟩
Journal articles pasteur-01499013v1
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Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action

Felipe Trajtenberg , Juan A Imelio , Matías R Machado , Nicole Larrieux , Marcelo A Marti
eLife, 2016, 5, pp.e21422. ⟨10.7554/eLife.21422⟩
Journal articles pasteur-02554309v1
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What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira.

Derrick E Fouts , Michael A Matthias , Haritha Adhikarla , Ben Adler , Luciane Amorim-Santos
PLoS Neglected Tropical Diseases, 2016, 10 (2), pp.e0004403. ⟨10.1371/journal.pntd.0004403⟩
Journal articles pasteur-01436457v1
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A novel flagellar sheath protein, FcpA, determines filament coiling, translational motility and virulence for the Leptospira spirochete

Elsio A. Jr Wunder , Cláudio Pereira Figueira , Nadia Benaroudj , Bo Hu , Brian Tong
Molecular Microbiology, 2016, 101 (3), pp.457-470. ⟨10.1111/mmi.13403⟩
Journal articles pasteur-02548535v1
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Structural Basis of Pullulanase Membrane Binding and Secretion Revealed by X-Ray Crystallography, Molecular Dynamics and Biochemical Analysis.

Alexandra East , Ariel E Mechaly , Gerard H M Huysmans , Cédric Bernarde , Diana Tello-Manigne
Structure, 2016, 24 (1), pp.92-104. ⟨10.1016/j.str.2015.10.023⟩
Journal articles pasteur-01498343v1

Data publication with the structural biology data grid supports live analysis

Peter A. Meyer , Stephanie Socias , Jason Key , Elizabeth Ransey , Emily C. Tjon
Nature Communications, 2016, 7, ⟨10.1038/ncomms10882⟩
Journal articles hal-01299025v1

A coiled coil switch mediates cold sensing by the thermosensory protein DesK

Emilio Saita , Luciano A Abriata , Yi Ting Tsai , Felipe Trajtenberg , Thomas Lemmin
Molecular Microbiology, 2015, 98 (2), pp.258-271. ⟨10.1111/mmi.13118⟩
Journal articles pasteur-02554124v1

Conformational plasticity of a native retroviral capsid revealed by x-ray crystallography

G. Obal , F. Trajtenberg , F. Carrión , L. Tomé , N. Larrieux
Science, 2015, 349 (6243), pp.95-98. ⟨10.1126/science.aaa5182⟩
Journal articles pasteur-02554123v1
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Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm

Stephen Methot , Ludivine Litzler , Felipe Trajtenberg , Astrid Zahn , Francis Robert
Journal of Experimental Medicine, 2015, 212 (4), pp.581-596. ⟨10.1084/jem.20141157⟩
Journal articles pasteur-02554122v1

Structural insights into bacterial resistance to cerulenin

Felipe Trajtenberg , Silvia Altabe , Nicole Larrieux , Florencia Ficarra , Diego de Mendoza
FEBS Journal, 2014, 281 (10), pp.2324-2338. ⟨10.1111/febs.12785⟩
Journal articles pasteur-02554118v1

HemR is an OmpR/PhoB-like response regulator from Leptospira, which simultaneously effects transcriptional activation and repression of key haem metabolism genes

Natalia R Morero , Horacio Botti , Kazuhiro Nitta , Federico Carrión , Gonzalo Obal
Molecular Microbiology, 2014, 94 (2), pp.340-352. ⟨10.1111/mmi.12763⟩
Journal articles pasteur-02554119v1
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Allosteric Activation of Bacterial Response Regulators: the Role of the Cognate Histidine Kinase Beyond Phosphorylation

Felipe Trajtenberg , Daniela Albanesi , Natalia Ruétalo , Horacio Botti , Ariel E Mechaly
mBio, 2014, 5 (6), pp.e02105. ⟨10.1128/mBio.02105-14⟩
Journal articles pasteur-02554121v1
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Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus.

Daniela Albanesi , Georgina Reh , Marcelo E Guerin , Francis Schaeffer , Michel Debarbouille
PLoS Pathogens, 2013, 9 (1), pp.e1003108. ⟨10.1371/journal.ppat.1003108⟩
Journal articles pasteur-00846686v1
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Structure of a human IgA1 Fab fragment at 1.55 Å resolution: potential effect of the constant domains on antigen-affinity modulation.

Agustin Correa , Felipe Trajtenberg , Gonzalo Obal , Otto Pritsch , Guillermo Dighiero
Acta crystallographica Section D : Structural biology [1993-..], 2013, 69 (Pt 3), pp.388-97. ⟨10.1107/S0907444912048664⟩
Journal articles pasteur-00847149v1
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The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-Specific Features and Regulatory Mechanisms.

Sofía Horjales , Dirk Schmidt-Arras , Ramiro Rodriguez Limardo , Olivier Leclercq , Gonzalo Obal
Structure, 2012, epub ahead of print. ⟨10.1016/j.str.2012.07.005⟩
Journal articles pasteur-00727033v1
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Trypanosoma cruzi trans-sialidase in complex with a neutralizing antibody: structure/function studies towards the rational design of inhibitors.

Alejandro Buschiazzo , Romina Muiá , Nicole Larrieux , Tamara Pitcovsky , Juan Mucci
PLoS Pathogens, 2012, 8 (1), pp.e1002474. ⟨10.1371/journal.ppat.1002474⟩
Journal articles pasteur-00686326v1
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Expression, crystallization and preliminary X-ray crystallographic analysis of glucose-6-phosphate dehydrogenase from the human pathogen Trypanosoma cruzi in complex with substrate.

Cecilia Ortíz , Nicole Larrieux , Andrea Medeiros , Horacio Botti , Marcelo Comini
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2011, 67 (Pt 11), pp.1457-61. ⟨10.1107/S1744309111037821⟩
Journal articles pasteur-00686320v1

Crystal structure of an enzymatically inactive trans-sialidase-like lectin from Trypanosoma cruzi: the carbohydrate binding mechanism involves residual sialidase activity.

Pablo Oppezzo , Gonzalo Obal , Martín A Baraibar , Otto Pritsch , Pedro M Alzari
BBA - Biochimica et Biophysica Acta, 2011, 1814 (9), pp.1154-61. ⟨10.1016/j.bbapap.2011.04.012⟩
Journal articles pasteur-00685050v1

Swapping FAD binding motifs between plastidic and bacterial ferredoxin-NADP(H) reductases.

Matías A Musumeci , Horacio Botti , Alejandro Buschiazzo , Eduardo A Ceccarelli
Biochemistry, 2011, 50 (12), pp.2111-22. ⟨10.1021/bi101772a⟩
Journal articles pasteur-00685048v1

Structural and enzymatic insights into the ATP binding and autophosphorylation mechanism of a sensor histidine kinase.

Felipe Trajtenberg , Martin Graña , Natalia Ruétalo , Horacio Botti , Alejandro Buschiazzo
Journal of Biological Chemistry, 2010, 285 (32), pp.24892-903. ⟨10.1074/jbc.M110.147843⟩
Journal articles pasteur-00508936v1

Evidence of adaptability in metal coordination geometry and active-site loop conformation among B1 metallo-beta-lactamases .

Javier M González , Alejandro Buschiazzo , Alejandro J Vila
Biochemistry, 2010, 49 (36), pp.7930-8. ⟨10.1021/bi100894r⟩
Journal articles pasteur-00684682v1

Crystal structure of Mycobacterium tuberculosis LppA, a lipoprotein confined to pathogenic mycobacteria.

Martin Graña , Marco Bellinzoni , Jacques Bellalou , Ahmed Haouz , Isabelle Miras
Proteins - Structure, Function and Bioinformatics, 2010, 78 (3), pp.769-72. ⟨10.1002/prot.22603⟩
Journal articles pasteur-00508937v1

Phylogenetic analysis of bovine leukemia viruses isolated in South America reveals diversification in seven distinct genotypes.

Gonzalo Moratorio , Gonzalo Obal , Ana Dubra , Agustín Correa , Sergio Bianchi
Archives of Virology, 2010, 155 (4), pp.481-9. ⟨10.1007/s00705-010-0606-3⟩
Journal articles pasteur-00684630v1

Structural plasticity and catalysis regulation of a thermosensor histidine kinase

Daniela Albanesi , Mariana Martin , Felipe Trajtenberg , María Mansilla , Ahmed Haouz
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (38), pp.16185-16190. ⟨10.1073/pnas.0906699106⟩
Journal articles pasteur-02554116v1

Structure of Mycobacterium tuberculosis Rv2714, a representative of a duplicated gene family in Actinobacteria.

Martin Graña , Marco Bellinzoni , Isabelle Miras , Cedric Fiez-Vandal , Ahmed Haouz
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2009, 65 (Pt 10), pp.972-7. ⟨10.1107/S1744309109035027⟩
Journal articles pasteur-00508938v1

Active nuclear import and cytoplasmic retention of activation-induced deaminase

Anne-Marie Patenaude , Alexandre Orthwein , Yi Hu , Vanina A Campo , Bodil Kavli
Nature Structural and Molecular Biology, 2009, 16 (5), pp.517-527. ⟨10.1038/nsmb.1598⟩
Journal articles pasteur-02554115v1

Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening

João Neres , Mark L Brewer , Laura Ratier , Horacio Botti , Alejandro Buschiazzo
Bioorganic and Medicinal Chemistry Letters, 2009, 19 (3), pp.589-596. ⟨10.1016/j.bmcl.2008.12.065⟩
Journal articles pasteur-02554114v1

Kinetic and Mechanistic Analysis of Trypanosoma cruzi Trans-Sialidase Reveals a Classical Ping-Pong Mechanism with Acid/Base Catalysis

Iben Damager , Sabrina Buchini , Maria F Amaya , Alejandro Buschiazzo , Pedro Alzari
Biochemistry, 2008, 47 (11), pp.3507-3512. ⟨10.1021/bi7024832⟩
Journal articles pasteur-02554111v1

Structural insights into sialic acid enzymology

Alejandro Buschiazzo , Pedro Alzari
Current Opinion in Chemical Biology, 2008, 12 (5), pp.565 - 572. ⟨10.1016/j.cbpa.2008.06.017⟩
Journal articles pasteur-02554113v1

A New Generation of Specific Trypanosoma Cruzi Trans-Sialidase Inhibitors

Sabrina Buchini , Alejandro Buschiazzo , Stephen G. Withers
Angewandte Chemie International Edition, 2008, 47 (14), pp.2700-2703. ⟨10.1002/anie.200705435⟩
Journal articles pasteur-02554112v1

Benzoic acid and pyridine derivatives as inhibitors of Trypanosoma cruzi trans-sialidase

João Neres , Pascal Bonnet , Philip N Edwards , Pravin L Kotian , Alejandro Buschiazzo
Bioorganic and Medicinal Chemistry, 2007, 15 (5), pp.2106-2119. ⟨10.1016/j.bmc.2006.12.024⟩
Journal articles pasteur-02554109v1

The crystal structure of Rv0813c from Mycobacterium tuberculosis reveals a new family of fatty acid-binding protein-like proteins in bacteria.

William Shepard , Ahmed Haouz , Martin Graña , Alejandro Buschiazzo , Jean-Michel Betton
Journal of Bacteriology, 2007, 189 (5), pp.1899-904. ⟨10.1128/JB.01435-06⟩
Journal articles pasteur-00508943v1

The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria.

Martin Graña , Ahmed Haouz , Alejandro Buschiazzo , Isabelle Miras , Annemarie Wehenkel
Protein Science, 2007, 16 (9), pp.1896-904. ⟨10.1110/ps.072982707⟩
Journal articles pasteur-00508941v1

Molecular Recognition and Interfacial Catalysis by the Essential Phosphatidylinositol Mannosyltransferase PimA from Mycobacteria

Marcelo E Guerin , Jana Korduláková , Francis Schaeffer , Zuzana Svetlikova , Alejandro Buschiazzo
Journal of Biological Chemistry, 2007, 282 (28), pp.20705-20714. ⟨10.1074/jbc.M702087200⟩
Journal articles pasteur-02554110v1

Continuous fluorimetric assay for high-throughput screening of inhibitors of trans-sialidase from Trypanosoma cruzi

João Neres , Alejandro Buschiazzo , Pedro Alzari , Lindsey Walsh , Kenneth T Douglas
Analytical Biochemistry, 2006, 357 (2), pp.302 - 304. ⟨10.1016/j.ab.2006.07.018⟩
Journal articles pasteur-02554106v1

Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma Rangeli Sialidase

Andrew G Watts , Pablo Oppezzo , Stephen Withers , Pedro Alzari , Alejandro Buschiazzo
Journal of Biological Chemistry, 2006, 281 (7), pp.4149-4155. ⟨10.1074/jbc.M510677200⟩
Journal articles pasteur-02554104v1

Structural basis of lipid biosynthesis regulation in Gram-positive bacteria

Gustavo E Schujman , Marcelo E Guerin , Alejandro Buschiazzo , Francis Schaeffer , Leticia I Llarrull
EMBO Journal, 2006, 25 (17), pp.4074-4083. ⟨10.1038/sj.emboj.7601284⟩
Journal articles pasteur-02554108v1

Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase

Alejandro Buschiazzo , Maira Goytia , Francis Schaeffer , Wim M. Degrave , William Shepard
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (6), pp.1705-1710. ⟨10.1073/pnas.0509010103⟩
Journal articles hal-02523212v1

Structural Biology and Crystallization Communications Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis

Marcelo E Guerin , Alejandro Buschiazzo , Jana Korduláková , Mary Jackson , Pedro Alzari
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2005, 61 (5), pp.518-520. ⟨10.1107/S1744309105012364⟩
Journal articles pasteur-02554105v1

Structural Insights Into the Catalytic Mechanism of Trypanosoma Cruzi Trans-Sialidase

María Fernanda Amaya , Andrew G Watts , Iben Damager , Annemarie Wehenkel , Tong Nguyen
Structure, 2004, 12 (5), pp.775 - 784. ⟨10.1016/j.str.2004.02.036⟩
Journal articles pasteur-02554101v1

Crystal Structure of Glycogen Synthase: Homologous Enzymes Catalyze Glycogen Synthesis and Degradation

Alejandro Buschiazzo , Juan E Ugalde , Marcelo E Guerin , William Shepard , Rodolfo A Ugalde
EMBO Journal, 2004, 23 (16), pp.3196 - 3205. ⟨10.1038/sj.emboj.7600324⟩
Journal articles pasteur-02554103v1

Preliminary Crystallographic Studies of Glycogen Synthase From Agrobacterium Tumefaciens

Marcelo E Guerin , Alejandro Buschiazzo , Juan E Ugalde , Rodolfo A Ugalde , Pedro Alzari
Acta crystallographica Section D : Structural biology [1993-..], 2003, 59 (3), pp.526-528. ⟨10.1107/s0907444902023119⟩
Journal articles pasteur-02554095v1

Trypanosoma cruzi Trans-sialidase Operates through a Covalent Sialyl-Enzyme Intermediate: Tyrosine Is the Catalytic Nucleophile

Andrew G Watts , Iben Damager , Maria L Amaya , Alejandro Buschiazzo , Pedro Alzari
Journal of the American Chemical Society, 2003, 125 (25), pp.7532-7533. ⟨10.1021/ja0344967⟩
Journal articles pasteur-02554098v1

The High Resolution Structures of Free and Inhibitor- bound Trypanosoma rangeli Sialidase and its Comparison with T. cruzi Trans-sialidase

Maria Fernanda Amaya , Alejandro Buschiazzo , Tong Nguyen , Pedro Alzari
Journal of Molecular Biology, 2003, 325 (4), pp.773-784. ⟨10.1016/S0022-2836(02)01306-2⟩
Journal articles pasteur-02554094v1

The Crystal Structure and Mode of Action of Trans-Sialidase, a Key Enzyme in Trypanosoma Cruzi Pathogenesis

Alejandro Buschiazzo , María Fernanda Amaya , María L Cremona , Alberto C Frasch , Pedro Alzari
Molecular Cell, 2002, 10 (4), pp.757 - 768. ⟨10.1016/s1097-2765(02)00680-9⟩
Journal articles pasteur-02554093v1

The trans-sialidase from the African trypanosome Trypanosoma brucei

Georgina Montagna , M. Laura Cremona , Gastón Paris , María Fernanda Amaya , Alejandro Buschiazzo
European Journal of Biochemistry, 2002, 269 (12), pp.2941-2950. ⟨10.1046/j.1432-1033.2002.02968.x⟩
Journal articles pasteur-02554091v1

Probing molecular function of trypanosomal sialidases: single point mutations can change substrate specificity and increase hydrolytic activity

Gaston Paris , Maria Laura Cremona , Maria Fernanda Amaya , Alejandro Buschiazzo , Susana Giambiagi
Glycobiology, 2001, 11 (4), pp.305 - 311. ⟨10.1093/glycob/11.4.305⟩
Journal articles pasteur-02554090v1

The tyrosine aminotransferase from Trypanosoma rangeli: sequence and genomic characterization

Esteban J Bontempi , Gabriela A Garcia , Alejandro Buschiazzo , Jan Henriksson , Carlos A Pravia
FEMS Microbiology Letters, 2000, 189 (2), pp.253-257. ⟨10.1111/j.1574-6968.2000.tb09239.x⟩
Journal articles pasteur-02554087v1

Structural basis of sialyltransferase activity in trypanosomal sialidases

Alejandro Buschiazzo , Gisele A Tavares , Oscar Campetella , Silvia Spinelli , Maria L Cremona
EMBO Journal, 2000, 19 (1), pp.16 - 24. ⟨10.1093/emboj/19.1.16⟩
Journal articles pasteur-02554089v1

Trypanosoma Rangeli Sialidase: Cloning, Expression and Similarity to T. Cruzi Trans-Sialidase

Alejandro Buschiazzo , Oscar Campetella , Alberto C Frasch
Glycobiology, 1997, 7 (8), pp.1167-1173. ⟨10.1093/glycob/7.8.1167⟩
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Medium scale production and purification to homogeneity of a recombinant trans-sialidase from Trypanosoma cruzi

Alberto Carlos C Frasch , Alejandro Buschiazzo , Oscar Campetella
Cellular and Molecular Biology, 1996, 42 (5), pp.703-10
Journal articles pasteur-02554066v1

Identification of the gene(s) coding for the trans-sialidase of Trypanosoma cruzi

Armando J Parodi , Guido D Pollevick , Martin Mautner , Alejandro Buschiazzo , Daniel O Sanchez
EMBO Journal, 1992, 1, pp.1 - 705
Journal articles hal-02554055v1

Sequence of the gene for a Trypanosoma cruzi protein antigenic during the chronic phase of human Chagas disease

Alejandro Buschiazzo , Oscar Campetella , Roberto A Macina , Susana Salceda , Alberto C.C. Frasch
Molecular and Biochemical Parasitology, 1992, 54 (1), pp.125-128. ⟨10.1016/0166-6851(92)90105-s⟩
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Protein Dynamics in Phosphoryl-Transfer Signaling Mediated by Two-Component Systems

Felipe Trajtenberg , Alejandro Buschiazzo
Histidine Phosphorylation, 2077, Humana, pp.1-18, 2020, Methods in Molecular Biology, 978-1-4939-9884-5. ⟨10.1007/978-1-4939-9884-5_1⟩
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