Alejandro Buschiazzo Group Leader

Publications

Article dans une revue (82)

Structural analysis of HER2-trastuzumab complex reveals receptor conformational adaptation Santiago Vacca,Marcos Gragera,Alejandro Buschiazzo,David Herreros,James Kriegeret al. Science Advances , 2025, 11 (30), pp.eadu9945. ⟨10.1126/sciadv.adu9945⟩ Article dans une revue pasteur-05218460v1
Human glutathione transferases catalyze the reaction between glutathione and nitrooleic acid Martina Steglich,Nicole Larrieux,Ari Zeida,Joaquín Dalla Rizza,Sonia R Salvatoreet al. Journal of Biological Chemistry, 2025, 301 (4), pp.108362. ⟨10.1016/j.jbc.2025.108362⟩ Article dans une revue pasteur-05121041v1
Signal-sensing triggers the shutdown of HemKR, regulating heme and iron metabolism in the spirochete Leptospira biflexa Juan Andrés Imelio,Felipe Trajtenberg,Sonia Mondino,Leticia Zarantonelli,Iakov Vitrenkoet al. PLoS ONE, 2024, 19 (9), pp.e0311040. ⟨10.1371/journal.pone.0311040⟩ Article dans une revue pasteur-05076650v1
Diving into the complexity of the spirochetal endoflagellum Fabiana San Martin,Lenka Fule,Gregorio Iraola,Alejandro Buschiazzo,Mathieu Picardeau Trends in Microbiology, 2023, 31 (3), pp.294-307. ⟨10.1016/j.tim.2022.09.010⟩ Article dans une revue (article de synthèse) pasteur-04117804v1
An allosteric switch ensures efficient unidirectional information transmission by the histidine kinase DesK from Bacillus subtilis Sofía Lima,Juan Blanco,Federico Olivieri,Juan Imelio,Marcos Nieveset al. Science Signaling, 2023, 16 (769), pp.eabo7588. ⟨10.1126/scisignal.abo7588⟩ Article dans une revue pasteur-04117648v1
Structural features of sensory two component systems: a synthetic biology perspective Marcos Nieves,Alejandro Buschiazzo,Felipe Trajtenberg Biochemical Journal, 2023, 480 (2), pp.127-140. ⟨10.1042/BCJ20210798⟩ Article dans une revue pasteur-04117794v1
Listeria innocua isolated from diseased ruminants harbour minor virulence genes of L. monocytogenes Carolina Matto,Bruno d'Alessandro,María Inés Mota,Valeria Braga,Alejandro Buschiazzoet al. Veterinary Medicine and Science, 2022, 8 (2), pp.735-740. ⟨10.1002/vms3.710⟩ Article dans une revue hal-04117822v1
Horizontal transfer of the rfb cluster in Leptospira is a genetic determinant of serovar identity Cecilia Nieves,Antony Vincent,Leticia Zarantonelli,Mathieu Picardeau,Frédéric Veyrieret al. Life Science Alliance, 2022, 6 (2), pp.e202201480. ⟨10.26508/lsa.202201480⟩ Article dans une revue pasteur-04117799v1
3D cryo-EM imaging of bacterial flagella: Novel structural and mechanistic insights into cell motility Sonia Mondino,Fabiana San Martin,Alejandro Buschiazzo Journal of Biological Chemistry, 2022, 298 (7), pp.102105. ⟨10.1016/j.jbc.2022.102105⟩ Article dans une revue pasteur-04117813v1
Allostery and protein plasticity: the keystones for bacterial signaling and regulation J. Imelio,F. Trajtenberg,Alejandro Buschiazzo Biophysical Reviews, 2021, 13 (6), pp.943-953. ⟨10.1007/s12551-021-00892-9⟩ Article dans une revue pasteur-04117817v1
Role of the major determinant of polar flagellation FlhG in the endoflagella‐containing spirochete Leptospira Lenka Fule,Ruben Halifa,Celia Fontana,Odile Sismeiro,Rachel Legendreet al. Molecular Microbiology, 2021, ⟨10.1111/mmi.14831⟩ Article dans une revue pasteur-03411258v1
The crystal structure of yeast regulatory subunit reveals key evolutionary insights into Protein Kinase A oligomerization Nicolás González Bardeci,Enzo Tofolón,Felipe Trajtenberg,Julio Caramelo,Nicole Larrieuxet al. Journal of Structural Biology, 2021, 213 (2), pp.107732. ⟨10.1016/j.jsb.2021.107732⟩ Article dans une revue hal-03246652v1
AID overexpression leads to aggressive murine CLL and non-Ig mutations that mirror human neoplasms. Pablo Elías Morande,Xiao-Jie Yan,Julieta Haydee Sepulveda-Yanez,Noé Seija,Maria Elena Marquezet al. Blood, 2021, ⟨10.1182/blood.2020008654⟩ Article dans une revue pasteur-03246646v1
Causes of abortion in dairy cows in Uruguay Melissa Macías-Rioseco,Caroline Silveira,Martin Fraga,Laura Casaux,Andrés Cabreraet al. Pesquisa Veterinária Brasileira, 2020, 40 (5), pp.325-332. ⟨10.1590/1678-5150-PVB-6550⟩ Article dans une revue pasteur-03246634v1
Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine Julia Lara,Lautaro Diacovich,Felipe Trajtenberg,Nicole Larrieux,Emilio L. Malchiodiet al. Nature Communications, 2020, 11 (1), pp.3703. ⟨10.1038/s41467-020-17504-x⟩ Article dans une revue pasteur-03246643v1
An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete Kimberley H Gibson,Felipe Trajtenberg,Elsio A. Jr Wunder,Megan R Brady,Fabiana San Martinet al. eLife, 2020, 9, ⟨10.7554/eLife.53672⟩ Article dans une revue pasteur-02549761v1
Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation Cecilia Ortíz,Horacio Botti,Alejandro Buschiazzo,Marcelo Comini Journal of Molecular Biology, 2019, 431 (11), pp.2143-2162. ⟨10.1016/j.jmb.2019.03.023⟩ Article dans une revue pasteur-02554318v1
Two-Component Sensing and Regulation: How Do Histidine Kinases Talk with Response Regulators at the Molecular Level? Alejandro Buschiazzo,Felipe Trajtenberg Annual Review of Microbiology, 2019, 73, pp.507-528. ⟨10.1146/annurev-micro-091018-054627⟩ Article dans une revue pasteur-02554319v1
Draft Genome Sequences of 40 Pathogenic Leptospira Strains Isolated from Cattle in Uruguay Cecilia Nieves,Ignacio Ferrés,Florencia Díaz-Viraqué,Alejandro Buschiazzo,Leticia Zarantonelliet al. Microbiology Resource Announcements, 2019, 8 (47), pp.e00893-19. ⟨10.1128/MRA.00893-19⟩ Article dans une revue pasteur-02554324v1
Molecular adaptations of NADP-malic enzyme for its function in C4 photosynthesis in grasses Clarisa Alvarez,Anastasiia Bovdilova,Astrid Höppner,Christian-Claus Wolff,Mariana Saigoet al. Nature Plants, 2019, 5 (7), pp.755-765. ⟨10.1038/s41477-019-0451-7⟩ Article dans une revue pasteur-02554321v1
Conformational plasticity of the response regulator CpxR, a key player in Gammaproteobacteria virulence and drug-resistance Ariel E Mechaly,Ahmed Haouz,Nathalie Sassoon,Alejandro Buschiazzo,Jean-Michel Bettonet al. Journal of Structural Biology, 2018, 204 (2), pp.165-171. ⟨10.1016/j.jsb.2018.08.001⟩ Article dans une revue hal-02322059v1
Isolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis Leticia Zarantonelli,Alejandra Suanes,Paulina Meny,Florencia Buroni,Cecilia Nieveset al. PLoS Neglected Tropical Diseases, 2018, 12 (9), pp.e0006694. ⟨10.1371/journal.pntd.0006694⟩ Article dans une revue pasteur-01881268v1
Lvr, a Signaling System That Controls Global Gene Regulation and Virulence in Pathogenic Leptospira Haritha Adhikarla,Elsio A. Jr Wunder,Ariel E Mechaly,Sameet Mehta,Zheng Wanget al. Frontiers in Cellular and Infection Microbiology, 2018, 8, pp.45. ⟨10.3389/fcimb.2018.00045⟩ Article dans une revue pasteur-02100138v1
The crystal structure of the malic enzyme from Candidatus Phytoplasma reveals the minimal structural determinants for a malic enzyme C. Alvarez,F. Trajtenberg,N. Larrieux,M. Saigo,A. Golicet al. Acta crystallographica Section D : Structural biology [1993-..], 2018, 74 (4), pp.332-340. ⟨10.1107/S2059798318002759⟩ Article dans une revue pasteur-02554314v1
SIMBAD: a sequence-independent molecular-replacement pipeline Adam J Simpkin,Felix Simkovic,Jens Thomas,Martin Savko,Andrey Lebedevet al. Acta crystallographica Section D : Structural biology [1993-..], 2018, 74 (7), pp.595-605. ⟨10.1107/S2059798318005752⟩ Article dans une revue pasteur-02554316v1
FcpB Is a Surface Filament Protein of the Endoflagellum Required for the Motility of the Spirochete Leptospira Elsio A. Jr Wunder,Leyla Slamti,David N Suwondo,Kimberley H Gibson,Zhiguo Shanget al. Frontiers in Cellular and Infection Microbiology, 2018, 8, pp.130. ⟨10.3389/fcimb.2018.00130⟩ Article dans une revue pasteur-02100036v1
Structural Coupling between Autokinase and Phosphotransferase Reactions in a Bacterial Histidine Kinase Ariel E Mechaly,Silvia Soto Diaz,Nathalie Sassoon,Alejandro Buschiazzo,Jean-Michel Bettonet al. Structure, 2017, 25 (6), pp.939-944.e3. ⟨10.1016/j.str.2017.04.011⟩ Article dans une revue pasteur-02554313v1
Snapshots of the Signaling Complex DesK:DesR in Different Functional States Using Rational Mutagenesis and X-ray Crystallography Juan A Imelio,Nicole Larrieux,Ariel E Mechaly,Felipe Trajtenberg,Alejandro Buschiazzo Bio-protocol , 2017, 7 (16), ⟨10.21769/BioProtoc.2510⟩ Article dans une revue pasteur-02872312v1
Crystallization of FcpA from Leptospira, a novel flagellar protein that is essential for pathogenesis Fabiana San Martin,Nicole Larrieux,Ariel E Mechaly,Elsio A. Jr Wunder,Albert I Koet al. Acta crystallographica Section F : Structural biology communications [2014-..], 2017, 73 (3), pp.123 - 129. ⟨10.1107/S2053230X17002096⟩ Article dans une revue pasteur-02554311v1
Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action Felipe Trajtenberg,Juan A Imelio,Matías R Machado,Nicole Larrieux,Marcelo A Martiet al. eLife, 2016, 5, pp.e21422. ⟨10.7554/eLife.21422⟩ Article dans une revue pasteur-02554309v1
Crystal Structure of the Metallo-β-Lactamase GOB in the Periplasmic Dizinc Form Reveals an Unusual Metal Site. Jorgelina Morán-Barrio,María-Natalia Lisa,Nicole Larrieux,Salvador I Drusin,Alejandro M Vialeet al. Antimicrobial Agents and Chemotherapy, 2016, 60 (10), pp.6013-22. ⟨10.1128/aac.01067-16⟩ Article dans une revue pasteur-01499013v1
Structural Basis of Pullulanase Membrane Binding and Secretion Revealed by X-Ray Crystallography, Molecular Dynamics and Biochemical Analysis. Alexandra East,Ariel E Mechaly,Gerard H M Huysmans,Cédric Bernarde,Diana Tello-Manigneet al. Structure, 2016, 24 (1), pp.92-104. ⟨10.1016/j.str.2015.10.023⟩ Article dans une revue pasteur-01498343v1
A novel flagellar sheath protein, FcpA, determines filament coiling, translational motility and virulence for the Leptospira spirochete Elsio A. Jr Wunder,Cláudio Pereira Figueira,Nadia Benaroudj,Bo Hu,Brian Tonget al. Molecular Microbiology, 2016, 101 (3), pp.457-470. ⟨10.1111/mmi.13403⟩ Article dans une revue pasteur-02548535v1
What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira. Derrick E Fouts,Michael A Matthias,Haritha Adhikarla,Ben Adler,Luciane Amorim-Santoset al. PLoS Neglected Tropical Diseases, 2016, 10 (2), pp.e0004403. ⟨10.1371/journal.pntd.0004403⟩ Article dans une revue pasteur-01436457v1
Data publication with the structural biology data grid supports live analysis Peter A. Meyer,Stephanie Socias,Jason Key,Elizabeth Ransey,Emily C. Tjonet al. Nature Communications, 2016, 7, ⟨10.1038/ncomms10882⟩ Article dans une revue hal-01299025v1
A coiled coil switch mediates cold sensing by the thermosensory protein DesK Emilio Saita,Luciano A Abriata,Yi Ting Tsai,Felipe Trajtenberg,Thomas Lemminet al. Molecular Microbiology, 2015, 98 (2), pp.258-271. ⟨10.1111/mmi.13118⟩ Article dans une revue pasteur-02554124v1
Conformational plasticity of a native retroviral capsid revealed by x-ray crystallography G. Obal,F. Trajtenberg,F. Carrión,L. Tomé,N. Larrieuxet al. Science, 2015, 349 (6243), pp.95-98. ⟨10.1126/science.aaa5182⟩ Article dans une revue pasteur-02554123v1
Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm Stephen Methot,Ludivine Litzler,Felipe Trajtenberg,Astrid Zahn,Francis Robertet al. Journal of Experimental Medicine, 2015, 212 (4), pp.581-596. ⟨10.1084/jem.20141157⟩ Article dans une revue pasteur-02554122v1
Allosteric Activation of Bacterial Response Regulators: the Role of the Cognate Histidine Kinase Beyond Phosphorylation Felipe Trajtenberg,Daniela Albanesi,Natalia Ruétalo,Horacio Botti,Ariel E Mechalyet al. mBio, 2014, 5 (6), pp.e02105. ⟨10.1128/mBio.02105-14⟩ Article dans une revue pasteur-02554121v1
HemR is an OmpR/PhoB-like response regulator from Leptospira, which simultaneously effects transcriptional activation and repression of key haem metabolism genes Natalia R Morero,Horacio Botti,Kazuhiro Nitta,Federico Carrión,Gonzalo Obalet al. Molecular Microbiology, 2014, 94 (2), pp.340-352. ⟨10.1111/mmi.12763⟩ Article dans une revue pasteur-02554119v1
Structural insights into bacterial resistance to cerulenin Felipe Trajtenberg,Silvia Altabe,Nicole Larrieux,Florencia Ficarra,Diego de Mendozaet al. FEBS Journal, 2014, 281 (10), pp.2324-2338. ⟨10.1111/febs.12785⟩ Article dans une revue pasteur-02554118v1
Structure of a human IgA1 Fab fragment at 1.55 Å resolution: potential effect of the constant domains on antigen-affinity modulation. Agustin Correa,Felipe Trajtenberg,Gonzalo Obal,Otto Pritsch,Guillermo Dighieroet al. Acta crystallographica Section D : Structural biology [1993-..], 2013, 69 (Pt 3), pp.388-97. ⟨10.1107/S0907444912048664⟩ Article dans une revue pasteur-00847149v1
Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus. Daniela Albanesi,Georgina Reh,Marcelo E Guerin,Francis Schaeffer,Michel Debarbouilleet al. PLoS Pathogens, 2013, 9 (1), pp.e1003108. ⟨10.1371/journal.ppat.1003108⟩ Article dans une revue pasteur-00846686v1
The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-Specific Features and Regulatory Mechanisms. Sofía Horjales,Dirk Schmidt-Arras,Ramiro Rodriguez Limardo,Olivier Leclercq,Gonzalo Obalet al. Structure, 2012, epub ahead of print. ⟨10.1016/j.str.2012.07.005⟩ Article dans une revue pasteur-00727033v1
Trypanosoma cruzi trans-sialidase in complex with a neutralizing antibody: structure/function studies towards the rational design of inhibitors. Alejandro Buschiazzo,Romina Muiá,Nicole Larrieux,Tamara Pitcovsky,Juan Mucciet al. PLoS Pathogens, 2012, 8 (1), pp.e1002474. ⟨10.1371/journal.ppat.1002474⟩ Article dans une revue pasteur-00686326v1
Expression, crystallization and preliminary X-ray crystallographic analysis of glucose-6-phosphate dehydrogenase from the human pathogen Trypanosoma cruzi in complex with substrate. Cecilia Ortíz,Nicole Larrieux,Andrea Medeiros,Horacio Botti,Marcelo Cominiet al. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2011, 67 (Pt 11), pp.1457-61. ⟨10.1107/S1744309111037821⟩ Article dans une revue pasteur-00686320v1
Crystal structure of an enzymatically inactive trans-sialidase-like lectin from Trypanosoma cruzi: the carbohydrate binding mechanism involves residual sialidase activity. Pablo Oppezzo,Gonzalo Obal,Martín A Baraibar,Otto Pritsch,Pedro M Alzariet al. BBA - Biochimica et Biophysica Acta, 2011, 1814 (9), pp.1154-61. ⟨10.1016/j.bbapap.2011.04.012⟩ Article dans une revue istex pasteur-00685050v1
Swapping FAD binding motifs between plastidic and bacterial ferredoxin-NADP(H) reductases. Matías A Musumeci,Horacio Botti,Alejandro Buschiazzo,Eduardo A Ceccarelli Biochemistry, 2011, 50 (12), pp.2111-22. ⟨10.1021/bi101772a⟩ Article dans une revue pasteur-00685048v1
Structural and enzymatic insights into the ATP binding and autophosphorylation mechanism of a sensor histidine kinase. Felipe Trajtenberg,Martin Graña,Natalia Ruétalo,Horacio Botti,Alejandro Buschiazzo Journal of Biological Chemistry, 2010, 285 (32), pp.24892-903. ⟨10.1074/jbc.M110.147843⟩ Article dans une revue pasteur-00508936v1
Crystal structure of Mycobacterium tuberculosis LppA, a lipoprotein confined to pathogenic mycobacteria. Martin Graña,Marco Bellinzoni,Jacques Bellalou,Ahmed Haouz,Isabelle Miraset al. Proteins - Structure, Function and Bioinformatics, 2010, 78 (3), pp.769-72. ⟨10.1002/prot.22603⟩ Article dans une revue istex pasteur-00508937v1
Evidence of adaptability in metal coordination geometry and active-site loop conformation among B1 metallo-beta-lactamases . Javier M González,Alejandro Buschiazzo,Alejandro J Vila Biochemistry, 2010, 49 (36), pp.7930-8. ⟨10.1021/bi100894r⟩ Article dans une revue pasteur-00684682v1
Phylogenetic analysis of bovine leukemia viruses isolated in South America reveals diversification in seven distinct genotypes. Gonzalo Moratorio,Gonzalo Obal,Ana Dubra,Agustín Correa,Sergio Bianchiet al. Archives of Virology, 2010, 155 (4), pp.481-9. ⟨10.1007/s00705-010-0606-3⟩ Article dans une revue istex pasteur-00684630v1
Structure of Mycobacterium tuberculosis Rv2714, a representative of a duplicated gene family in Actinobacteria. Martin Graña,Marco Bellinzoni,Isabelle Miras,Cedric Fiez-Vandal,Ahmed Haouzet al. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2009, 65 (Pt 10), pp.972-7. ⟨10.1107/S1744309109035027⟩ Article dans une revue pasteur-00508938v1
Structural plasticity and catalysis regulation of a thermosensor histidine kinase Daniela Albanesi,Mariana Martin,Felipe Trajtenberg,María Mansilla,Ahmed Haouzet al. Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (38), pp.16185-16190. ⟨10.1073/pnas.0906699106⟩ Article dans une revue pasteur-02554116v1
Active nuclear import and cytoplasmic retention of activation-induced deaminase Anne-Marie Patenaude,Alexandre Orthwein,Yi Hu,Vanina A Campo,Bodil Kavliet al. Nature Structural and Molecular Biology, 2009, 16 (5), pp.517-527. ⟨10.1038/nsmb.1598⟩ Article dans une revue pasteur-02554115v1
Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening João Neres,Mark L Brewer,Laura Ratier,Horacio Botti,Alejandro Buschiazzoet al. Bioorganic and Medicinal Chemistry Letters, 2009, 19 (3), pp.589-596. ⟨10.1016/j.bmcl.2008.12.065⟩ Article dans une revue istex pasteur-02554114v1
Kinetic and Mechanistic Analysis of Trypanosoma cruzi Trans-Sialidase Reveals a Classical Ping-Pong Mechanism with Acid/Base Catalysis Iben Damager,Sabrina Buchini,Maria F Amaya,Alejandro Buschiazzo,Pedro Alzariet al. Biochemistry, 2008, 47 (11), pp.3507-3512. ⟨10.1021/bi7024832⟩ Article dans une revue istex pasteur-02554111v1
Structural insights into sialic acid enzymology Alejandro Buschiazzo,Pedro Alzari Current Opinion in Chemical Biology, 2008, 12 (5), pp.565 - 572. ⟨10.1016/j.cbpa.2008.06.017⟩ Article dans une revue istex pasteur-02554113v1
A New Generation of Specific Trypanosoma Cruzi Trans-Sialidase Inhibitors Sabrina Buchini,Alejandro Buschiazzo,Stephen G. Withers Angewandte Chemie International Edition, 2008, 47 (14), pp.2700-2703. ⟨10.1002/anie.200705435⟩ Article dans une revue istex pasteur-02554112v1
Benzoic acid and pyridine derivatives as inhibitors of Trypanosoma cruzi trans-sialidase João Neres,Pascal Bonnet,Philip N Edwards,Pravin L Kotian,Alejandro Buschiazzoet al. Bioorganic and Medicinal Chemistry, 2007, 15 (5), pp.2106-2119. ⟨10.1016/j.bmc.2006.12.024⟩ Article dans une revue istex pasteur-02554109v1
Molecular Recognition and Interfacial Catalysis by the Essential Phosphatidylinositol Mannosyltransferase PimA from Mycobacteria Marcelo E Guerin,Jana Korduláková,Francis Schaeffer,Zuzana Svetlikova,Alejandro Buschiazzoet al. Journal of Biological Chemistry, 2007, 282 (28), pp.20705-20714. ⟨10.1074/jbc.M702087200⟩ Article dans une revue pasteur-02554110v1
The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria. Martin Graña,Ahmed Haouz,Alejandro Buschiazzo,Isabelle Miras,Annemarie Wehenkelet al. Protein Science, 2007, 16 (9), pp.1896-904. ⟨10.1110/ps.072982707⟩ Article dans une revue pasteur-00508941v1
The crystal structure of Rv0813c from Mycobacterium tuberculosis reveals a new family of fatty acid-binding protein-like proteins in bacteria. William Shepard,Ahmed Haouz,Martin Graña,Alejandro Buschiazzo,Jean-Michel Bettonet al. Journal of Bacteriology, 2007, 189 (5), pp.1899-904. ⟨10.1128/JB.01435-06⟩ Article dans une revue pasteur-00508943v1
Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma Rangeli Sialidase Andrew G Watts,Pablo Oppezzo,Stephen Withers,Pedro Alzari,Alejandro Buschiazzo Journal of Biological Chemistry, 2006, 281 (7), pp.4149-4155. ⟨10.1074/jbc.M510677200⟩ Article dans une revue pasteur-02554104v1
Continuous fluorimetric assay for high-throughput screening of inhibitors of trans-sialidase from Trypanosoma cruzi João Neres,Alejandro Buschiazzo,Pedro Alzari,Lindsey Walsh,Kenneth T Douglas Analytical Biochemistry, 2006, 357 (2), pp.302 - 304. ⟨10.1016/j.ab.2006.07.018⟩ Article dans une revue istex pasteur-02554106v1
Structural basis of lipid biosynthesis regulation in Gram-positive bacteria Gustavo E Schujman,Marcelo E Guerin,Alejandro Buschiazzo,Francis Schaeffer,Leticia I Llarrullet al. EMBO Journal, 2006, 25 (17), pp.4074-4083. ⟨10.1038/sj.emboj.7601284⟩ Article dans une revue pasteur-02554108v1
Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase Alejandro Buschiazzo,Maira Goytia,Francis Schaeffer,Wim M. Degrave,William Shepardet al. Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (6), pp.1705-1710. ⟨10.1073/pnas.0509010103⟩ Article dans une revue hal-02523212v1
Structural Biology and Crystallization Communications Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis Marcelo E Guerin,Alejandro Buschiazzo,Jana Korduláková,Mary Jackson,Pedro Alzari Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2005, 61 (5), pp.518-520. ⟨10.1107/S1744309105012364⟩ Article dans une revue pasteur-02554105v1
Structural Insights Into the Catalytic Mechanism of Trypanosoma Cruzi Trans-Sialidase María Fernanda Amaya,Andrew G Watts,Iben Damager,Annemarie Wehenkel,Tong Nguyenet al. Structure, 2004, 12 (5), pp.775 - 784. ⟨10.1016/j.str.2004.02.036⟩ Article dans une revue pasteur-02554101v1
Crystal Structure of Glycogen Synthase: Homologous Enzymes Catalyze Glycogen Synthesis and Degradation Alejandro Buschiazzo,Juan E Ugalde,Marcelo E Guerin,William Shepard,Rodolfo A Ugaldeet al. EMBO Journal, 2004, 23 (16), pp.3196 - 3205. ⟨10.1038/sj.emboj.7600324⟩ Article dans une revue pasteur-02554103v1
Trypanosoma cruzi Trans-sialidase Operates through a Covalent Sialyl-Enzyme Intermediate: Tyrosine Is the Catalytic Nucleophile Andrew G Watts,Iben Damager,Maria L Amaya,Alejandro Buschiazzo,Pedro Alzariet al. Journal of the American Chemical Society, 2003, 125 (25), pp.7532-7533. ⟨10.1021/ja0344967⟩ Article dans une revue istex pasteur-02554098v1
Preliminary Crystallographic Studies of Glycogen Synthase From Agrobacterium Tumefaciens Marcelo E Guerin,Alejandro Buschiazzo,Juan E Ugalde,Rodolfo A Ugalde,Pedro Alzari Acta crystallographica Section D : Structural biology [1993-..], 2003, 59 (3), pp.526-528. ⟨10.1107/s0907444902023119⟩ Article dans une revue istex pasteur-02554095v1
The High Resolution Structures of Free and Inhibitor- bound Trypanosoma rangeli Sialidase and its Comparison with T. cruzi Trans-sialidase Maria Fernanda Amaya,Alejandro Buschiazzo,Tong Nguyen,Pedro Alzari Journal of Molecular Biology, 2003, 325 (4), pp.773-784. ⟨10.1016/S0022-2836(02)01306-2⟩ Article dans une revue istex pasteur-02554094v1
The Crystal Structure and Mode of Action of Trans-Sialidase, a Key Enzyme in Trypanosoma Cruzi Pathogenesis Alejandro Buschiazzo,María Fernanda Amaya,María L Cremona,Alberto C Frasch,Pedro Alzari Molecular Cell, 2002, 10 (4), pp.757 - 768. ⟨10.1016/s1097-2765(02)00680-9⟩ Article dans une revue pasteur-02554093v1
The trans-sialidase from the African trypanosome Trypanosoma brucei Georgina Montagna,M. Laura Cremona,Gastón Paris,María Fernanda Amaya,Alejandro Buschiazzoet al. European Journal of Biochemistry, 2002, 269 (12), pp.2941-2950. ⟨10.1046/j.1432-1033.2002.02968.x⟩ Article dans une revue pasteur-02554091v1
Probing molecular function of trypanosomal sialidases: single point mutations can change substrate specificity and increase hydrolytic activity Gaston Paris,Maria Laura Cremona,Maria Fernanda Amaya,Alejandro Buschiazzo,Susana Giambiagiet al. Glycobiology, 2001, 11 (4), pp.305 - 311. ⟨10.1093/glycob/11.4.305⟩ Article dans une revue pasteur-02554090v1
The tyrosine aminotransferase from Trypanosoma rangeli: sequence and genomic characterization Esteban J Bontempi,Gabriela A Garcia,Alejandro Buschiazzo,Jan Henriksson,Carlos A Praviaet al. FEMS Microbiology Letters, 2000, 189 (2), pp.253-257. ⟨10.1111/j.1574-6968.2000.tb09239.x⟩ Article dans une revue pasteur-02554087v1
Structural basis of sialyltransferase activity in trypanosomal sialidases Alejandro Buschiazzo,Gisele A Tavares,Oscar Campetella,Silvia Spinelli,Maria L Cremonaet al. EMBO Journal, 2000, 19 (1), pp.16 - 24. ⟨10.1093/emboj/19.1.16⟩ Article dans une revue pasteur-02554089v1
Trypanosoma Rangeli Sialidase: Cloning, Expression and Similarity to T. Cruzi Trans-Sialidase Alejandro Buschiazzo,Oscar Campetella,Alberto C Frasch Glycobiology, 1997, 7 (8), pp.1167-1173. ⟨10.1093/glycob/7.8.1167⟩ Article dans une revue pasteur-02554085v1
Medium scale production and purification to homogeneity of a recombinant trans-sialidase from Trypanosoma cruzi Alberto Carlos C Frasch,Alejandro Buschiazzo,Oscar Campetella Cellular and Molecular Biology, 1996, 42 (5), pp.703-10 Article dans une revue hal-02554066v1
Identification of the gene(s) coding for the trans-sialidase of Trypanosoma cruzi Armando J Parodi,Guido D Pollevick,Martin Mautner,Alejandro Buschiazzo,Daniel O Sanchezet al. EMBO Journal, 1992, 1, pp.1 - 705 Article dans une revue hal-02554055v1
Sequence of the gene for a Trypanosoma cruzi protein antigenic during the chronic phase of human Chagas disease Alejandro Buschiazzo,Oscar Campetella,Roberto A Macina,Susana Salceda,Alberto C.C. Fraschet al. Molecular and Biochemical Parasitology, 1992, 54 (1), pp.125-128. ⟨10.1016/0166-6851(92)90105-s⟩ Article dans une revue istex pasteur-02554058v1

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