Alexandre Benmerah

Documents

Research domains

Cellular Biology Development Biology Genetics Urology and Nephrology

Skills

Publications

	Agonists of prostaglandin E 2 receptors as potential first in class treatment for nephronophthisis and related ciliopathies Hugo Garcia , Alice Serafin , Flora Silbermann , Esther Porée , Amandine Viau Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (18), pp.e2115960119. ⟨10.1073/pnas.2115960119⟩ Journal articles hal-03930843v1
	Biallelic KIF24 variants are responsible for a spectrum of skeletal disorders ranging from lethal skeletal ciliopathy to severe acromesomelic dysplasia Madeline Louise Reilly , Noor Ul Ain , Mari Muurinen , Alice Tata , Céline Huber Journal of Bone and Mineral Research, inPress, ⟨10.1002/jbmr.4639⟩ Journal articles hal-03705297v1
	EFA6A, an exchange factor for Arf6, regulates early steps in ciliogenesis Mariagrazia Partisani , Carole L Baron , Rania Ghossoub , Racha Fayad , Sophie Pagnotta Journal of Cell Science, 2021, 134 (2), pp.jcs249565. ⟨10.1242/jcs.249565⟩ Journal articles hal-03120586v1
	KIF14 controls ciliogenesis via regulation of Aurora A and is important for Hedgehog signaling Petra Pejskova , Madeline Louise Reilly , Lucia Bino , Ondrej Bernatik , Linda Dolanska Journal of Cell Biology, 2020, 219 (6), ⟨10.1083/jcb.201904107⟩ Journal articles hal-03843901v1
	Cilia in hereditary cerebral anomalies Sophie Thomas , Lucile Boutaud , Madeline Louise Reilly , Alexandre Benmerah Biology of the Cell, 2019, ⟨10.1111/boc.201900012⟩ Journal articles inserm-02263786v1
	Ciliary kinesins beyond IFT: cilium length, disassembly, cargo transport and signaling Madeline Louise Reilly , Alexandre Benmerah Biology of the Cell, 2019, 111 (4), pp.79-94. ⟨10.1111/boc.201800074⟩ Journal articles inserm-02263784v1
	Loss of function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish Madeline Louise Reilly , Marijn F Stokman , Virginie Magry , Cécile Jeanpierre , Marine Alves Human Molecular Genetics, 2019, 28 (5), pp.778-795. ⟨10.1093/hmg/ddy381⟩ Journal articles inserm-02263778v1
	Human IFT52 mutations uncover a novel role for the protein in microtubule dynamics and centrosome cohesion Marie Alice Dupont , Camille Humbert , Céline Huber , Quentin Siour , Ida Chiara Guerrera Human Molecular Genetics, 2019, 28, pp.2720-2737. ⟨10.1093/hmg/ddz091⟩ Journal articles hal-02391689v1
	Functional characterization of tektin-1 in motile cilia and evidence for TEKT1 as a new candidate gene for motile ciliopathies Rebecca Ryan , Marion Failler , Madeline Louise Reilly , Meriem Garfa-Traoré , Marion Delous Human Molecular Genetics, 2018, 27 (2), pp.266-282. ⟨10.1093/hmg/ddx396⟩ Journal articles inserm-02263788v1
	Morphological and Functional Characterization of the Ciliary Pocket by Electron and Fluorescence Microscopy Rania Ghossoub , Louise Lindbæk , Anahi Mollà-Herman , Alain Schmitt , Søren Tvorup Christensen Methods in Molecular Biology, 2016, 1454, 1454 (1454), pp.35-51. ⟨10.1007/978-1-4939-3789-9_3⟩ Journal articles hal-02353046v1
	The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies. Alexandre Benmerah , Bénédicte Durand , Rachel H Giles , Tess Harris , Linda Kohl Cilia, 2015, 4 (1), pp.5. ⟨10.1186/s13630-015-0014-0⟩ Journal articles pasteur-01514418v1
	Rab4b controls an early endosome sorting event by interacting with the -subunit of the clathrin adaptor complex 1 Perrin Laura , Lacas-Gervais Sandra , Gilleron Jérôme , Ceppo Franck , Prodon François Journal of Cell Science, 2013, 126 (21), pp.4950-4962. ⟨10.1242/jcs.130575⟩ Journal articles hal-02109081v1
	Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length Rania Ghossoub , Qicong Hu , Marion Failler , Marie-Christine Rouyez , Benjamin Spitzbarth Journal of Cell Science, 2013, 126 (12), pp.2583 - 2594. ⟨10.1242/jcs.111377⟩ Journal articles hal-02646477v1
	The ciliary pocket Alexandre Benmerah Current Opinion in Cell Biology, 2013, 25 (1), pp.78-84. ⟨10.1016/j.ceb.2012.10.011⟩ Journal articles inserm-02263810v1
	The ciliary pocket: a once-forgotten membrane domain at the base of cilia Rania Ghossoub , Anahi Mollà-Herman , Philippe Bastin , Alexandre Benmerah Biology of the Cell, 2011, 103 (3), pp.131-144. ⟨10.1042/BC20100128⟩ Journal articles inserm-02263813v1
	Endocytosis and toxicity of clostridial binary toxins depend on a clathrin-independent pathway regulated by Rho-GDI Maryse Gibert , Marie-Noelle Monier , Richard Ruez , Martha Hale , Bradley Stiles Cellular Microbiology, 2011, 13 (1), pp.154 - 170. ⟨10.1111/j.1462-5822.2010.01527.x⟩ Journal articles pasteur-01762176v1
	The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia Anahi Mollà-Herman , Rania Ghossoub , Thierry Blisnick , Alice Meunier , Catherine Serres Journal of Cell Science, 2010, 123 (10), pp.1785-1795. ⟨10.1242/jcs.059519⟩ Journal articles hal-02353018v1
	Targeting of β-Arrestin2 to the Centrosome and Primary Cilium: Role in Cell Proliferation Control Anahi Mollà-Herman , Cédric Boularan , Rania Ghossoub , Mark G.H. Scott , Anne Burtey PLoS ONE, 2008, 3 (11), pp.e3728. ⟨10.1371/journal.pone.0003728⟩ Journal articles hal-02353001v1
	Clinical, cellular, and neuropathological consequences of AP1S2 mutations: further delineation of a recognizable X-linked mental retardation syndrome Guntram Borck , Anahi Mollà-Herman , Nathalie Boddaert , Ferechte Encha-Razavi , Anne Philippe Human Mutation, 2008, 29 (7), pp.966-974. ⟨10.1002/humu.20531⟩ Journal articles hal-02044435v1
	beta-arrestin 2 oligomerization controls the Mdm2-dependent inhibition of p53. Cédric Boularan , Mark G.H. Scott , Karima Bourougaa , Myriam Bellal , Emmanuel Esteve Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (46), pp.18061-6. ⟨10.1073/pnas.0705550104⟩ Journal articles inserm-00174967v1
	Clathrin-Coated Pits: Vive La Différence? Alexandre Benmerah , Christophe Lamaze Traffic, 2007, 8 (8), pp.970-982. ⟨10.1111/j.1600-0854.2007.00585.x⟩ Journal articles hal-03844131v1
	Intracellular Trafficking of CD23: Differential Regulation in Humans and Mice by Both Extracellular and Intracellular Exons Guillaume Montagnac , Anahi Mollà-Herman , Jérôme Bouchet , Linda Yu , Daniel Conrad Journal of Immunology, 2005, 174 (9), pp.5562-5572. ⟨10.4049/jimmunol.174.9.5562⟩ Journal articles hal-02352965v1
	Analysis of the AP-2 adaptor complex and cargo during clathrin-mediated endocytosis. Joshua Z. Rappoport , Alexandre Benmerah , Sanford M. Simon Traffic, 2005, 6 (7), pp.539-47. ⟨10.1111/j.1600-0854.2005.00280.x⟩ Journal articles inserm-00142398v1
	Intracellular Trafficking of CD23: Differential Regulation in Humans and Mice by Both Extracellular and Intracellular Exons Guillaume Montagnac , Anahi Mollà-Herman , Jérôme Bouchet , Linda Yu , Daniel Conrad Journal of Immunology, 2005, 174 (9), pp.5562-5572. ⟨10.4049/jimmunol.174.9.5562⟩ Journal articles hal-02351248v1
	Endocytosis: Signaling from Endocytic Membranes to the Nucleus Alexandre Benmerah Current Biology - CB, 2004, 14 (8), pp.R314-R316. ⟨10.1016/j.cub.2004.03.053⟩ Journal articles hal-03844176v1
	Understanding Living Clathrin-Coated Pits Joshua Rappoport , Sanford Simon , Alexandre Benmerah Traffic, 2004, 5 (5), pp.327-337. ⟨10.1111/j.1398-9219.2004.00187.x⟩ Journal articles hal-03844168v1
	Protéines Nef du VIH et K3/K5 du virus associé au sarcoma de Kaposi : des « parasites »de la voie d’endocytose Serge Bénichou , Alexandre Benmerah Médecine/Sciences, 2003, 19 (1), pp.100-106. ⟨10.1051/medsci/2003191100⟩ Journal articles hal-03844197v1
	Nuclear Functions for Plasma Membrane-Associated Proteins? Alexandre Benmerah , Mark Scott , Viviane Poupon , Stefano Marullo Traffic, 2003, 4 (8), pp.503-511. ⟨10.1034/j.1600-0854.2003.00102.x⟩ Journal articles hal-03844201v1
	Differential nucleocytoplasmic trafficking between the related endocytic proteins Eps15 and Eps15R. Viviane Poupon , Simona Polo , Manuela Vecchi , Gwendal Martin , Alice Dautry-Varsat Journal of Biological Chemistry, 2002, 277 (11), pp.8941-8. ⟨10.1074/jbc.M108385200⟩ Journal articles pasteur-00166958v1
	Mapping of Eps15 Domains Involved in Its Targeting to Clathrin-coated Pits Alexandre Benmerah , Viviane Poupon , Nadine Cerf-Bensussan , Alice Dautry-Varsat Journal of Biological Chemistry, 2000, 275 (5), pp.3288-3295. ⟨10.1074/jbc.275.5.3288⟩ Journal articles hal-03844263v1
	Molecular Cloning and Characterization of MT-ACT48, a Novel Mitochondrial Acyl-CoA Thioesterase Viviane Poupon , Bernadette Bègue , Jean Gagnon , Alice Dautry-Varsat , Nadine Cerf-Bensussan Journal of Biological Chemistry, 1999, 274 (27), pp.19188-19194. ⟨10.1074/jbc.274.27.19188⟩ Journal articles hal-03844267v1

	Alteration of nephrocystins and IFT-A proteins causes similar ciliary phenotypes leading to Nephronophthisis Sophie Saunier , Albane A. Bizet , Flora Silbermann , Emilie Filhol , Thierry Blisnick First International Cilia in Development and Disease Scientific Conference, May 2012, London, United Kingdom. pp.P99, ⟨10.1186/2046-2530-1-S1-P99⟩ Conference papers inserm-00752970v1

	Monitoring β-arrestin2 targeting to the centrosome, basal body and primary cilium by fluorescence microscopy Anahi Mollà-Herman , Kathryn M Davis , Kirk Mykytyn , Alexandre Benmerah Methods Mol Biol, 1454, pp.271-289, 2019, ⟨10.1007/978-1-4939-9158-7_17⟩ Book sections inserm-02263790v1
	Morphological and Functional Characterization of the Ciliary Pocket by Electron and Fluorescence Microscopy Rania Ghossoub , Louise Lindbæk , Anahi Mollà-Herman , Alain Schmitt , Søren Tvorup Christensen Methods Mol Biol, 1454, pp.35-51, 2016, ⟨10.1007/978-1-4939-3789-9_3⟩ Book sections inserm-02263792v1

Alexandre Benmerah

Research domains

Skills

Publications

Agonists of prostaglandin E 2 receptors as potential first in class treatment for nephronophthisis and related ciliopathies

Biallelic KIF24 variants are responsible for a spectrum of skeletal disorders ranging from lethal skeletal ciliopathy to severe acromesomelic dysplasia

EFA6A, an exchange factor for Arf6, regulates early steps in ciliogenesis

KIF14 controls ciliogenesis via regulation of Aurora A and is important for Hedgehog signaling

Cilia in hereditary cerebral anomalies

Ciliary kinesins beyond IFT: cilium length, disassembly, cargo transport and signaling

Loss of function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish

Human IFT52 mutations uncover a novel role for the protein in microtubule dynamics and centrosome cohesion

Functional characterization of tektin-1 in motile cilia and evidence for TEKT1 as a new candidate gene for motile ciliopathies

Morphological and Functional Characterization of the Ciliary Pocket by Electron and Fluorescence Microscopy

The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies.

Rab4b controls an early endosome sorting event by interacting with the -subunit of the clathrin adaptor complex 1

Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length

The ciliary pocket

The ciliary pocket: a once-forgotten membrane domain at the base of cilia

Endocytosis and toxicity of clostridial binary toxins depend on a clathrin-independent pathway regulated by Rho-GDI

The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia

Targeting of β-Arrestin2 to the Centrosome and Primary Cilium: Role in Cell Proliferation Control

Clinical, cellular, and neuropathological consequences of AP1S2 mutations: further delineation of a recognizable X-linked mental retardation syndrome

beta-arrestin 2 oligomerization controls the Mdm2-dependent inhibition of p53.

Clathrin-Coated Pits: Vive La Différence?

Intracellular Trafficking of CD23: Differential Regulation in Humans and Mice by Both Extracellular and Intracellular Exons

Analysis of the AP-2 adaptor complex and cargo during clathrin-mediated endocytosis.

Intracellular Trafficking of CD23: Differential Regulation in Humans and Mice by Both Extracellular and Intracellular Exons

Endocytosis: Signaling from Endocytic Membranes to the Nucleus

Understanding Living Clathrin-Coated Pits

Protéines Nef du VIH et K3/K5 du virus associé au sarcoma de Kaposi : des « parasites »de la voie d’endocytose

Nuclear Functions for Plasma Membrane-Associated Proteins?

Differential nucleocytoplasmic trafficking between the related endocytic proteins Eps15 and Eps15R.

Mapping of Eps15 Domains Involved in Its Targeting to Clathrin-coated Pits

Molecular Cloning and Characterization of MT-ACT48, a Novel Mitochondrial Acyl-CoA Thioesterase

Alteration of nephrocystins and IFT-A proteins causes similar ciliary phenotypes leading to Nephronophthisis

Monitoring β-arrestin2 targeting to the centrosome, basal body and primary cilium by fluorescence microscopy

Morphological and Functional Characterization of the Ciliary Pocket by Electron and Fluorescence Microscopy