Alexandre G. de Brevern Senior Researcher (INSERM) - DSIMB Bioinformatics Team Director

Identifiants chercheurs

IdHAL :

alexandre-de-brevern

ORCID :

0000-0001-7112-5626

IdRef :

135431697

ResearcherID :

http://www.researcherid.com/rid/B-4788-2009

Présentation

Trained as a Cell Biologist, Alexandre G. de Brevern is a Structural Bioinformatician for now near 25 years. Senior Researcher at the French National Institute for Health and Medical Research (INSERM), he is the head of DSIMB, the Bioinformatics team of INSERM UMR_S 1134 BIGR unit (12 permanent researchers located in Paris, mainland France and Saint-Denis de la Reunion, Réunion Island in Indian Ocean). He has two main axes of researches: (i) developing innovate methodologies useful for the scientific community and (ii) specific application to proteins implicated in diseases and pathologies.Concerning the first axis, he provided more than 20 tools, webservers and databases mainly dealing with the analyses and prediction of protein behaviours, e.g. superimposition of protein structures and prediction of protein flexibility.He is a recognized specialist of protein local conformations with the extension of definition of beta-turn classes, new assignment for PolyProline II helices, analysis beta-bulge, comparison of different secondary structure assignment and the dynamics of secondary structure and implications on prediction. He is the designer of the most important structural alphabet, i.e. series of local protein prototypes able to approximate protein structures, the Protein Blocks. PBs have been used to analyse protein structures, protein structure dynamics, disordered proteins, defined binding sites, performed protein superimposition and prediction, …For prediction purposes, he used biostatistics and learning approaches ranging from Bayesian approach, to Artificial Neural Networks, Support Vector Machines and Deep Learning.Concerning the second axis, he used mainly structural modelling and molecular dynamics to analyse protein for Red Blood Cells and platelets. He is specialized in transmembrane proteins and protein implicated in blood group transfusion.He also extended his work to drug design with collaborations with companies and Next-Generation Sequencing. He had authored more than 180 publications (including 152 papers indexed in PubMed and one book), is editor in 8 peer-reviewed journals (one as Editor-In-Chief and two as Section editor). He is implicated in numerous scientific societies, being awarded by French Molecular Modelling group award (GGMM 2001) and Prix Maurice Nicloux 2011 award (Biochemical and Molecular Biology Society). He is involved in many institutes evaluation in France, Czech Republic and Poland and has International collaborations with India, Taiwan, Poland, Serbia, United Kingdom, Sweden and Serbia.Publication list can be found at http://www.dsimb.inserm.fr/~debrevern/PUBLICATIONS/index.php

Publications

Article dans une revue (133)

PATHOS: Predicting variant pathogenicity by combining protein language models and biological features Ragousandirane Radjasandirane,Gabriel Cretin,Julien Diharce,Alexandre G de Brevern,Jean-Christophe Gelly Artificial Intelligence in the Life Sciences, In press, 9, ⟨10.1016/j.ailsci.2026.100165⟩ Article dans une revue hal-05571678v1
Using protein blocks to build custom fragment libraries from protein structures Surbhi Dhingra,Stéphane Téletchéa,Ramanathan Sowdhamini,Yves-Henri Sanejouand,Alexandre de Brevernet al. Biochimie, 2025, ⟨10.1016/j.biochi.2025.08.011⟩ Article dans une revue (article de synthèse) hal-05354334v1
Insights for variant clinical interpretation based on a benchmark of 65 variant effect predictors Ragousandirane Radjasandirane,Julien Diharce,Jean-Christophe Gelly,Alexandre G de Brevern Genomics, 2025, 117, ⟨10.1016/j.ygeno.2025.111036⟩ Article dans une revue hal-05110149v1
Molecular dynamics of the human RhD and RhAG blood group proteins Aline Floch,Tatiana Galochkina,France Pirenne,Christophe Tournamille,Alexandre G de Brevern Frontiers in Chemistry, 2024, 12, pp.1360392. ⟨10.3389/fchem.2024.1360392⟩ Article dans une revue inserm-04510947v1
HumanLectome, an update of UniLectin for the annotation and prediction of human lectins Boris Schnider,Yacine M’rad,Jalaa El Ahmadie,Alexandre G de Brevern,Anne Imbertyet al. Nucleic Acids Research, 2024, 52 (D1), pp.D1683 - D1693. ⟨10.1093/nar/gkad905⟩ Article dans une revue hal-04376368v1
Lysosomal damage due to cholesterol accumulation triggers immunogenic cell death Karla Alvarez-Valadez,Allan Sauvat,Julien Diharce,Marion Leduc,Gautier Stollet al. Autophagy, 2024, 08, pp.1-23. ⟨10.1080/15548627.2024.2440842⟩ Article dans une revue hal-04875040v1
General Trends of the Camelidae Antibody VHHs Domain Dynamics Akhila Melarkode Vattekatte,Julien Diharce,Joseph Rebehmed,Frédéric Cadet,Fabrice Gardebienet al. International Journal of Molecular Sciences, 2023, 24, pp.4511. ⟨10.3390/ijms24054511⟩ Article dans une revue inserm-04258550v1
Structural Space of the Duffy Antigen/Receptor for Chemokines’ Intrinsically Disordered Ectodomain 1 Explored by Temperature Replica-Exchange Molecular Dynamics Simulations Agata Kranjc,Tarun Jairaj Narwani,Sophie Abby,Alexandre de Brevern International Journal of Molecular Sciences, 2023, 24 (17), pp.13280. ⟨10.3390/ijms241713280⟩ Article dans une revue hal-04256911v1
AlphaFold2 Update and Perspectives Sébastien Tourlet,Ragousandirane Radjasandirane,Julien Diharce,Alexandre G de Brevern BioMedInformatics, 2023, 3, pp.378 - 390. ⟨10.3390/biomedinformatics3020025⟩ Article dans une revue inserm-04258522v1
BioMedInformatics, the Link between Biomedical Informatics, Biology and Computational Medicine Alexandre G de Brevern BioMedInformatics, 2023, 4, pp.1 - 7. ⟨10.3390/biomedinformatics4010001⟩ Article dans une revue inserm-04510907v1
Evaluation of Transmembrane Protein Structural Models Using HPMScore Stéphane Téletchéa,Jérémy Esque,Aurélie Urbain,Catherine Etchebest,Alexandre G de Brevern BioMedInformatics, 2023, 3 (2), pp.306 - 326. ⟨10.3390/biomedinformatics3020021⟩ Article dans une revue hal-04813790v1
A perspective on the sharing of docking data Samia Aci-Sèche,Stéphane Bourg,Pascal Bonnet,Joseph Rebehmed,Alexandre de Brevernet al. Data in Brief, 2023, 49 (22), pp.109386. ⟨10.1016/j.dib.2023.109386⟩ Article dans une revue hal-04251910v1
Prediction of structural alphabet protein blocks using data mining Mirjana Maljković,Nenad Mitić,Alexandre de Brevern Biochimie, 2022, 197, pp.74-85. ⟨10.1016/j.biochi.2022.01.019⟩ Article dans une revue hal-03652564v1
Current status of PTMs structural databases: applications, limitations and prospects Alexandre de Brevern,Joseph Rebehmed Amino Acids, 2022, 54 (4), pp.575-590. ⟨10.1007/s00726-021-03119-z⟩ Article dans une revue hal-03690712v1
Analysis of Integrin αIIb Subunit Dynamics Reveals Long-Range Effects of Missense Mutations on Calf Domains Sali Anies,Vincent Jallu,Julien Diharce,Tarun J Narwani,Alexandre G de Brevern International Journal of Molecular Sciences, 2022, 23 (2), pp.858. ⟨10.3390/ijms23020858⟩ Article dans une revue hal-03542900v1
New αIIbβ3 variants in 28 Turkish Glanzmann patients; structural hypothesis for complex activation by residues variations in I-EGF domains M Koker,N Sarper,C Albayrak,B Zulfikar,E Zenginet al. Platelets, 2022, 33 (4), pp.551-561. ⟨10.1080/09537104.2021.1947481⟩ Article dans une revue hal-03684658v1
CALR-ETdb, the database of calreticulin variants diversity in essential thrombocythemia Nora El Jahrani,Gabriel Cretin,Alexandre de Brevern Platelets, 2022, 33 (1), pp.157-167. ⟨10.1080/09537104.2020.1869712⟩ Article dans une revue hal-03695851v1
VHH Structural Modelling Approaches: A Critical Review Poonam Vishwakarma,Akhila Melarkode Vattekatte,Nicolas Shinada,Julien Diharce,Carla Martinset al. International Journal of Molecular Sciences, 2022, 23 (7), pp.3721. ⟨10.3390/ijms23073721⟩ Article dans une revue hal-03665842v1
SWORD2: hierarchical analysis of protein 3D structures Gabriel Cretin,Tatiana Galochkina,Yann Vander Meersche,Alexandre G de Brevern,Guillaume Posticet al. Nucleic Acids Research, 2022, 50 (W1), pp.W732--W738. ⟨10.1093/nar/gkac370⟩ Article dans une revue hal-03738483v1
Transient association between proteins elicits alteration of dynamics at sites far away from interfaces Himani Tandon,Alexandre de Brevern,Narayanaswamy Srinivasan Structure, 2021, 29 (4), pp.371-384.e3. ⟨10.1016/j.str.2020.11.015⟩ Article dans une revue inserm-03543689v1
Conformational Strain Indicated by Ramachandran Angles for the Protein Backbone Is Only Weakly Related to the Flexibility Ashraya Ravikumar,Alexandre de Brevern,Narayanaswamy Srinivasan Journal of Physical Chemistry B, 2021, 125 (10), pp.2597-2606. ⟨10.1021/acs.jpcb.1c00168⟩ Article dans une revue hal-03549944v1
Hierarchical Structure of Protein Sequence Alexei Nekrasov,Yuri Kozmin,Sergey Kozyrev,Rustam Ziganshin,Alexandre de Brevernet al. International Journal of Molecular Sciences, 2021, 22 (15), pp.8339. ⟨10.3390/ijms22158339⟩ Article dans une revue hal-03538152v1
A Review of the Literature Organized Into a New Database: RHeference Aline Floch,Stéphane Téletchéa,Christophe Tournamille,Alexandre de Brevern,France Pirenne Transfusion Medicine Reviews, 2021, 35 (2), pp.70-77. ⟨10.1016/j.tmrv.2021.04.002⟩ Article dans une revue inserm-03253477v1
PYTHIA: Deep Learning Approach for Local Protein Conformation Prediction Gabriel Cretin,Tatiana Galochkina,Alexandre de Brevern,Jean-Christophe Gelly International Journal of Molecular Sciences, 2021, 22 (16), pp.8831. ⟨10.3390/ijms22168831⟩ Article dans une revue hal-03822577v1
Structural and evolutionary exploration of the IL-3 family and its alpha subunit receptors Jade Fogha,Jagadeesh Bayry,Julien Diharce,Alexandre de Brevern Amino Acids, 2021, 53 (8), pp.1211-1227. ⟨10.1007/s00726-021-03026-3⟩ Article dans une revue hal-03538521v1
Insights into Comparative Modeling of VHH Domains Akhila Melarkode Vattekatte,Frédéric Cadet,Jean-Christophe Gelly,Alexandre de Brevern International Journal of Molecular Sciences, 2021, 22 (18), pp.9771. ⟨10.3390/ijms22189771⟩ Article dans une revue hal-03537422v1
Insights into anti‐D formation in carriers of RhD variants through studies of 3D intraprotein interactions Aline Floch,France Pirenne,Aurélie Barrault,Btissam Chami,Cécile Toly‐ndouret al. Transfusion, 2021, 61 (4), pp.1286-1301. ⟨10.1111/trf.16301⟩ Article dans une revue inserm-03253510v1
ABCG2 Is Overexpressed on Red Blood Cells in Ph-Negative Myeloproliferative Neoplasms and Potentiates Ruxolitinib-Induced Apoptosis Ralfs Buks,Mégane Brusson,Sylvie Cochet,Tatiana Galochkina,Bruno Cassinatet al. International Journal of Molecular Sciences, 2021, 22 (7), pp.3530. ⟨10.3390/ijms22073530⟩ Article dans une revue hal-03531056v1
A structural entropy index to analyse local conformations in intrinsically disordered proteins Akhila Melarkode Vattekatte,Tarun Jairaj Narwani,Aline Floch,Mirjana Maljković,Soubika Bisooet al. Journal of Structural Biology, 2020, 210 (1), pp.107464. ⟨10.1016/j.jsb.2020.107464⟩ Article dans une revue inserm-02907335v1
Investigating the Product Profiles and Structural Relationships of New Levansucrases with Conventional and Non-Conventional Substrates Andrea Hill,Salwa Karboune,Tarun Narwani,Alexandre de Brevern International Journal of Molecular Sciences, 2020, 21 (15), pp.5402. ⟨10.3390/ijms21155402⟩ Article dans une revue inserm-02913693v1
Analysis of Protein Disorder Predictions in the Light of a Protein Structural Alphabet Alexandre de Brevern Biomolecules, 2020, 10 (7), pp.1080. ⟨10.3390/biom10071080⟩ Article dans une revue inserm-02907391v1
Accurate Representation of Protein-Ligand Structural Diversity in the Protein Data Bank (PDB) Nicolas K Shinada,Peter Schmidtke,Alexandre de Brevern International Journal of Molecular Sciences, 2020, 21 (6), pp.2243. ⟨10.3390/ijms21062243⟩ Article dans une revue inserm-02907370v1
Data set of intrinsically disordered proteins analysed at a local protein conformation level Akhila Melarkode Vattekatte,Tarun Jairaj Narwani,Aline Floch,Mirjana Maljković,Soubika Bisooet al. Data in Brief, 2020, 29, pp.105383. ⟨10.1016/j.dib.2020.105383⟩ Article dans une revue inserm-02907359v1
Discrete analysis of camelid variable domains: sequences, structures, and in-silico structure prediction Akhila Melarkode Vattekatte,Nicolas Ken Shinada,Tarun J Narwani,Floriane Noël,Olivier Bertrandet al. PeerJ, 2020, 8, pp.e8408. ⟨10.7717/peerj.8408⟩ Article dans une revue inserm-02907323v1
In silico prediction of protein flexibility with local structure approach Tarun J. Narwani,Catherine Etchebest,Pierrick Craveur,Sylvain Léonard,Joseph Rebehmedet al. Biochimie, 2019, 165, pp.150-155. ⟨10.1016/j.biochi.2019.07.025⟩ Article dans une revue inserm-02266143v1
Halogens in Protein−Ligand Binding Mechanism: A Structural Perspective Nicolas Shinada,Alexandre de Brevern,Peter Schmidtke Journal of Medicinal Chemistry, 2019, 62 (21), pp.9341-9356. ⟨10.1021/acs.jmedchem.8b01453⟩ Article dans une revue inserm-02913756v1
Benchmarking the PEPOP methods for mimicking discontinuous epitopes Vincent Demolombe,Alexandre de Brevern,Franck Molina,Géraldine Lavigne,Claude Granieret al. BMC Bioinformatics, 2019, 20 (1), pp.738. ⟨10.1186/s12859-019-3189-3⟩ Article dans une revue hal-02787607v2
Structural variations within proteins can be as large as variations observed across their homologues Iyanar Vetrivel,Alexandre de Brevern,Frédéric Cadet,Narayanaswamy Srinivasan,Bernard Offmann Biochimie, 2019, 167, pp.162-170. ⟨10.1016/j.biochi.2019.09.013⟩ Article dans une revue inserm-02913845v1
PEPOP 2.0: new approaches to mimic non-continuous epitopes Vincent Demolombe,Alexandre de Brevern,Liza L. Felicori,Christophe Nguyen,Ricardo Andrez Machado de Avilaet al. BMC Bioinformatics, 2019, 20 (1), ⟨10.1186/s12859-019-2867-5⟩ Article dans une revue hal-02277257v1
Long-range molecular dynamics show that inactive forms of Protein Kinase A are more dynamic than active forms R. Kalaivani,T. J Narwani,Alexandre de Brevern,N. Srinivasan Protein Science, 2019, 28 (3), pp.543-560. ⟨10.1002/pro.3556⟩ Article dans une revue inserm-02913871v1
Discrete analyses of protein dynamics Akhila Melarkode Vattekatte,Tarun Jairaj Narwani,Pierrick Craveur,Nicolas K Shinada,Aline Flochet al. Journal of Biomolecular Structure and Dynamics, 2019, pp.1-15. ⟨10.1080/07391102.2019.1650112⟩ Article dans une revue inserm-02266159v1
Dimerization and phosphorylation of Lutheran/basal cell adhesion molecule are critical for its function in cell migration on laminin Anna Guadall,Sylvie Cochet,Olivier Renaud,Yves Colin,Caroline Le van Kimet al. Journal of Biological Chemistry, 2019, 294 (41), pp.14911-14921. ⟨10.1074/jbc.RA119.007521⟩ Article dans une revue hal-02416861v1
Prediction of the intestinal resistome by a three-dimensional structure-based method Etienne Ruppé,Amine Ghozlane,Julien Tap,Nicolas Pons,Anne-Sophie Alvarezet al. Nature Microbiology, 2019, 4 (1), pp.112-123. ⟨10.1038/s41564-018-0292-6⟩ Article dans une revue pasteur-02552015v1
Investigation of the impact of PTMs on the protein backbone conformation Pierrick Craveur,Tarun Narwani,Joseph Rebehmed,Alexandre de Brevern Amino Acids, 2019, 51 (7), pp.1065-1079. ⟨10.1007/s00726-019-02747-w⟩ Article dans une revue inserm-02266176v1
Short in-Frame Insertions/Deletions in the Coding Sequence of the α-Globin Gene. Consequences of the 3D Structure and Resulting Phenotypes: Hb Choisy as an Example Henri Wajcman,Alexandre de Brevern,Jean Riou,Céline Latouche,Michael C. Mardenet al. Hemoglobin, 2019, 42 (5-6), pp.287-293. ⟨10.1080/03630269.2018.1556683⟩ Article dans une revue inserm-02913864v1
A minimum set of stable blocks for rational design of polypeptide chains Running head: A set of stable blocks for protein rational design Alexei N Nekrasov,Ludmila G Alekseeva,Rudolf А. Pogosyan,Dmitry A Dolgikh,M.P. P Kirpichnikovet al. Biochimie, 2019, 160, pp.88-92. ⟨10.1016/j.biochi.2019.02.006⟩ Article dans une revue inserm-02266188v1
iPBAvizu: a PyMOL plugin for an efficient 3D protein structure superimposition approach Guilhem Faure,Agnel Praveen Joseph,Pierrick Craveur,Tarun Narwani,Narayanaswamy Srinivasanet al. Source Code for Biology and Medicine, 2019, 14 (1), ⟨10.1186/s13029-019-0075-3⟩ Article dans une revue inserm-02913723v1
Protein local conformations at the light of a structural alphabet Alexandre de Brevern Biophysical Journal, 2018, 114 (3), pp.231A. ⟨10.1016/j.bpj.2017.11.1286⟩ Article dans une revue inserm-01852960v1
Analysing the Structural Effect of Point Mutations of Cytotoxic Necrotizing Factor 1 (CNF1) on Lu/BCAM Adhesion Glycoprotein Association Alexandre de Brevern Toxins, 2018, 10 (3), pp.E122. ⟨10.3390/toxins10030122⟩ Article dans une revue inserm-01852766v1
Dynamics and deformability of α-, 310- and π-helices Tarun Narwani,Pierrick Craveur,Nicolas Shinada,Hubert Santuz,Joseph Rebehmedet al. Archives of Biological Science, 2018, 70 (1), pp.21-31. ⟨10.2298/ABS170215022N⟩ Article dans une revue inserm-01585114v1
Same but not alike: Structure, flexibility and energetics of domains in multi-domain proteins are influenced by the presence of other domains Sneha Vishwanath,Alexandre de Brevern,Narayanaswamy Srinivasan PLoS Computational Biology, 2018, 14 (2), pp.e1006008. ⟨10.1371/journal.pcbi.1006008⟩ Article dans une revue inserm-02147944v1
Recent advances on polyproline II. Tarun Jairaj Narwani,Hubert Santuz,Nicolas Shinada,Akhila Melarkode Vattekatte,Yassine Ghouzamet al. Amino Acids, 2017, 49 (4), pp.705-713. ⟨10.1007/s00726-017-2385-6⟩ Article dans une revue inserm-01573940v1
Molecular characterization of 13 new RHD alleles Aline Floch,Aurelie Barrault,Alexandre de Brevern,Jennifer Martret,Kevin Gaillardet al. Transfusion, 2017, 57 (4), pp. 1089-1091. ⟨10.1111/trf.14004⟩ Article dans une revue hal-01627823v1
Knowledge-based prediction of protein backbone conformation using a structural alphabet Iyanar Vetrivel,Swapnil Mahajan,Manoj Tyagi,Lionel Hoffmann,Yves-Henri Sanejouandet al. PLoS ONE, 2017, 12 (11), pp.e0186215. ⟨10.1371/journal.pone.0186215⟩ Article dans une revue hal-01677391v1
Global analysis of VHHs framework regions with a structural alphabet Floriane Noël,Alain Malpertuy,Alexandre de Brevern Biochimie, 2016, 131, pp.11 - 19. ⟨10.1016/j.biochi.2016.09.005⟩ Article dans une revue inserm-01374633v1
Extension of the classical classification of β-turns Alexandre de Brevern Scientific Reports, 2016, pp.33191 ⟨10.1038/srep33191⟩ Article dans une revue inserm-01374651v1
Use of a structural alphabet to find compatible folds for amino acid sequences Swapnil Mahajan,Alexandre de Brevern,Yves-Henri Sanejouand,Narayanaswamy Srinivasan,Bernard Offmann Protein Science, 2015, 24 (1), pp.145 - 153. ⟨10.1002/pro.2581⟩ Article dans une revue hal-01677393v1
Bioinformatic analysis of the protein/DNA interface. Bohdan Schneider,Jirí Cerny,Daniel Svozil,Petr Cech,Jean-Christophe Gellyet al. Nucleic Acids Research, 2014, 42 (5), pp.3381-94. ⟨10.1093/nar/gkt1273⟩ Article dans une revue inserm-00926088v1
mulPBA: an efficient multiple protein structure alignment method based on a structural alphabet. Sylvain Léonard,Agnel Praveen Joseph,Narayanaswamy Srinivasan,Jean-Christophe Gelly,Alexandre de Brevern Journal of Biomolecular Structure and Dynamics, 2014, 32 (4), pp.661-8. ⟨10.1080/07391102.2013.787026⟩ Article dans une revue inserm-00926338v1
Correlation between local structural dynamics of proteins inferred from NMR ensembles and evolutionary dynamics of homologues of known structure. Swapnil Mahajan,Alexandre de Brevern,Bernard Offmann,Narayanaswamy Srinivasan Journal of Biomolecular Structure and Dynamics, 2014, 32 (5), pp.751-8. ⟨10.1080/07391102.2013.789989⟩ Article dans une revue inserm-00926204v1
Cis-trans isomerization of omega dihedrals in proteins. Pierrick Craveur,Agnel Praveen Joseph,Pierre Poulain,Joseph Rebehmed,Alexandre de Brevern Amino Acids, 2013, 45 (2), pp.279-89. ⟨10.1007/s00726-013-1511-3⟩ Article dans une revue istex inserm-00926521v1
VLDP web server: a powerful geometric tool for analysing protein structures in their environment. Jérémy Esque,Sylvain Léonard,Alexandre de Brevern,Christophe Oguey Nucleic Acids Research, 2013, 41 (Web Server issue), pp.W373-8. ⟨10.1093/nar/gkt509⟩ Article dans une revue inserm-00926547v1
DoSA: Database of Structural Alignments. Swapnil Mahajan,Garima Agarwal,Mohammed Iftekhar,Bernard Offmann,Alexandre de Brevernet al. Database - The journal of Biological Databases and Curation, 2013, 2013, pp.bat048. ⟨10.1093/database/bat048⟩ Article dans une revue inserm-00926452v1
Evolution study of the Baeyer-Villiger monooxygenases enzyme family: functional importance of the highly conserved residues. Joseph Rebehmed,Véronique Alphand,Véronique de Berardinis,Alexandre de Brevern Biochimie, 2013, 95 (7), pp.1394-402. ⟨10.1016/j.biochi.2013.03.005⟩ Article dans une revue inserm-00926584v1
Understanding the role of domain-domain linkers in the spatial orientation of domains in multi-domain proteins. Ramachandra M Bhaskara,Alexandre de Brevern,Narayanaswamy Srinivasan Journal of Biomolecular Structure and Dynamics, 2013, 31 (12), pp.1467-80. ⟨10.1080/07391102.2012.743438⟩ Article dans une revue inserm-00926595v1
β-Bulges: extensive structural analyses of β-sheets irregularities. Pierrick Craveur,Agnel Praveen Joseph,Joseph Rebehmed,Alexandre de Brevern Protein Science, 2013, 22 (10), pp.1366-78. ⟨10.1002/pro.2324⟩ Article dans une revue inserm-00926388v1
PRR repeats in the intracellular domain of KISS1R are important for its export to cell membrane. Lucie Chevrier,Alexandre de Brevern,Eva Hernandez,Jérome Leprince,Hubert Vaudryet al. Mol Endocrinol, 2013, 27 (6), pp.1004-14. ⟨10.1210/me.2012-1386⟩ Article dans une revue inserm-00926577v1
Comparison of tertiary structures of proteins in protein-protein complexes with unbound forms suggests prevalence of allostery in signalling proteins. Lakshmipuram S. Swapna,Swapnil Mahajan,Alexandre de Brevern,Narayanaswamy Srinivasan BMC Structural Biology, 2012, 12 (1), pp.6. ⟨10.1186/1472-6807-12-6⟩ Article dans une revue inserm-00725334v1
Cis-trans peptide variations in structurally similar proteins. Agnel Praveen Joseph,Narayanaswamy Srinivasan,Alexandre de Brevern Amino Acids, 2012, 43 (3), pp.1369-81. ⟨10.1007/s00726-011-1211-9⟩ Article dans une revue inserm-00680773v1
Selective constraint on human pre-mRNA splicing by protein structural properties. Jean-Christophe Gelly,Hsuan-Yu Lin,Alexandre de Brevern,Trees-Juen Chuang,Feng-Chi Chen Genome Biology and Evolution, 2012, 4 (9), pp.966-75. ⟨10.1093/gbe/evs071⟩ Article dans une revue inserm-00750397v1
Modeling and molecular dynamics of HPA-1a and -1b polymorphisms: effects on the structure of the β3 subunit of the αIIbβ3 integrin. Vincent Jallu,Pierre Poulain,Patrick F. J. Fuchs,Cécile Kaplan,Alexandre de Brevern PLoS ONE, 2012, 7 (11), pp.e47304. ⟨10.1371/journal.pone.0047304⟩ Article dans une revue inserm-00926600v1
Local structural differences in homologous proteins: specificities in different SCOP classes. Agnel Praveen Joseph,Hélène Valadié,Narayanaswamy Srinivasan,Alexandre de Brevern PLoS ONE, 2012, 7 (6), pp.e38805. ⟨10.1371/journal.pone.0038805⟩ Article dans une revue inserm-00750286v1
PredyFlexy: flexibility and local structure prediction from sequence. Alexandre de Brevern,Aurélie Bornot,Pierrick Craveur,Catherine Etchebest,Jean-Christophe Gelly Nucleic Acids Research, 2012, 40 (Web Server issue), pp.W317-22. ⟨10.1093/nar/gks482⟩ Article dans une revue inserm-00750270v1
Progressive structure-based alignment of homologous proteins: Adopting sequence comparison strategies. Agnel Praveen Joseph,Narayanaswamy Srinivasan,Alexandre de Brevern Biochimie, 2012, 94 (9), pp.2025-34. ⟨10.1016/j.biochi.2012.05.028⟩ Article dans une revue inserm-00750325v1
Le cahier de laboratoire électronique (CLE) Anabelle Amiard,Céline Baczynski,Christophe Blanchet,Alexandre de Brevern,Emmanuelle Dorlanne-Messiaenet al. STP Pharma Pratiques, 2011, 21 (6), pp.475-503 Article dans une revue inserm-00680791v1
Species specific amino acid sequence-protein local structure relationships: An analysis in the light of a structural alphabet. Alexandre de Brevern,Agnel Praveen Joseph Journal of Theoretical Biology, 2011, 276 (1), pp.209-17. ⟨10.1016/j.jtbi.2011.01.047⟩ Article dans une revue inserm-00646218v1
Species specific amino acid sequence - Protein local structure relationships: An analysis in the light of a structural alphabet Alexandre de Brevern,Agnel Praveen Joseph,Hélène Valadié Journal of Theoretical Biology, 2011, 276 (1), pp.209. ⟨10.1016/j.jtbi.2011.01.047⟩ Article dans une revue hal-00682413v1
iPBA: a tool for protein structure comparison using sequence alignment strategies. Jean-Christophe Gelly,Agnel Praveen Joseph,Narayanaswamy Srinivasan,Alexandre de Brevern Nucleic Acids Research, 2011, 39 (Web Server issue), pp.W18-23. ⟨10.1093/nar/gkr333⟩ Article dans une revue inserm-00646241v1
Identification of local conformational similarity in structurally variable regions of homologous proteins using protein blocks. Garima Agarwal,Swapnil Mahajan,Narayanaswamy Srinivasan,Alexandre de Brevern PLoS ONE, 2011, 6 (3), pp.e17826. ⟨10.1371/journal.pone.0017826⟩ Article dans une revue inserm-00586691v1
Improvement of protein structure comparison using a structural alphabet. Agnel Praveen Joseph,Narayanaswamy Srinivasan,Alexandre de Brevern Biochimie, 2011, 93 (9), pp.1434-45. ⟨10.1016/j.biochi.2011.04.010⟩ Article dans une revue inserm-00646245v1
Predicting protein flexibility through the prediction of local structures. Aurélie Bornot,Catherine Etchebest,Alexandre de Brevern Proteins - Structure, Function and Bioinformatics, 2011, 79 (3), pp.839-52. ⟨10.1002/prot.22922⟩ Article dans une revue inserm-00568171v1
Protein Peeling 3D: new tools for analyzing protein structures. Jean-Christophe Gelly,Alexandre de Brevern Bioinformatics, 2011, 27 (1), pp.132-3. ⟨10.1093/bioinformatics/btq610⟩ Article dans une revue inserm-00568165v1
Assignment of PolyProline II Conformation and Analysis of Sequence - Structure Relationship. Yohann Mansiaux,Agnel Praveen Joseph,Jean-Christophe Gelly,Alexandre de Brevern PLoS ONE, 2011, 6 (3), pp.e18401. ⟨10.1371/journal.pone.0018401⟩ Article dans une revue inserm-00586725v1
Comparative analysis of threshold and tessellation methods for determining protein contacts. Jeremy Esque,Christophe Oguey,Alexandre de Brevern Journal of Chemical Information and Modeling, 2011, 51 (2), pp.493-507. ⟨10.1021/ci100195t⟩ Article dans une revue inserm-00568174v1
Influence of assignment on the prediction of transmembrane helices in protein structures. Jean Pylouster,Aurélie Bornot,Catherine Etchebest,Alexandre de Brevern Amino Acids, 2010, 39 (5), pp.1241-54. ⟨10.1007/s00726-010-0559-6⟩ Article dans une revue istex inserm-00472869v1
Observer avec un nouvel oeil la structure des protéines et leur flexibilité. Alexandre de Brevern Regard sur la biochimie, 2010, 2010 (4), pp.3 Article dans une revue inserm-00557286v1
A short survey on protein blocks. Agnel Joseph,Garima Agarwal,Swapnil Mahajan,Jean-Christophe Gelly,Lakshmipuram S. Swapnaet al. Biophysical Reviews, 2010, 2 (3), pp.137-147. ⟨10.1007/s12551-010-0036-1⟩ Article dans une revue inserm-00512823v1
A novel evaluation of residue and protein volumes by means of Laguerre tessellation. Jeremy Esque,Christophe Oguey,Alexandre de Brevern Journal of Chemical Information and Modeling, 2010, 50 (5), pp.947-60. ⟨10.1021/ci9004892⟩ Article dans une revue inserm-00473943v1
Comparative analysis of missing value imputation methods to improve clustering and interpretation of microarray experiments. Magalie Celton,Alain Malpertuy,Gaëlle Lelandais,Alexandre de Brevern BMC Genomics, 2010, 11 (1), pp.15. ⟨10.1186/1471-2164-11-15⟩ Article dans une revue inserm-00663912v1
A recombinant dromedary antibody fragment (VHH or nanobody) directed against human Duffy antigen receptor for chemokines. Dorota Smolarek,Claude Hattab,Gholamreza Hassanzadeh-Ghassabeh,Sylvie Cochet,Carlos Gutiérrezet al. Cellular and Molecular Life Sciences, 2010, 67 (19), pp.3371-87. ⟨10.1007/s00018-010-0387-6⟩ Article dans une revue inserm-00512838v1
Fast and automated functional classification with MED-SuMo: an application on purine-binding proteins. Olivia Doppelt-Azeroual,François Delfaud,Fabrice Moriaud,Alexandre de Brevern Protein Science, 2010, 19 (4), pp.847-67. ⟨10.1002/pro.364⟩ Article dans une revue inserm-00458093v1
Multiple interests in structural models of DARC transmembrane protein. Dorota Smolarek,Olivier Bertrand,Marcin Czerwinski,Yves Colin,Catherine Etchebestet al. Transfusion Clinique et Biologique, 2010, 17 (3), pp.184-96. ⟨10.1016/j.tracli.2010.05.003⟩ Article dans une revue inserm-00506537v1
AlphaIIbbeta3 integrin: new allelic variants in Glanzmann thrombasthenia, effects on ITGA2B and ITGB3 mRNA splicing, expression, and structure-function. Vincent Jallu,Mathilde Dusseaux,Simon Panzer,Marie-Françoise Torchet,Nathalie Hezardet al. Human Mutation, 2010, 31 (3), pp.237-46. ⟨10.1002/humu.21179⟩ Article dans une revue istex inserm-00448024v1
3D Structural Models of Transmembrane Proteins. Alexandre de Brevern Methods in Molecular Biology, 2010, 654, pp.387-401. ⟨10.1007/978-1-60761-762-4_20⟩ Article dans une revue inserm-00507094v1
A dominant mutation in the gene encoding the erythroid transcription factor KLF1 causes a congenital dyserythropoietic anemia. Lionel Arnaud,Carole Saison,Virginie Helias,Nicole Lucien,Dominique Steschenkoet al. American Journal of Human Genetics, 2010, 87 (5), pp.721-7. ⟨10.1016/j.ajhg.2010.10.010⟩ Article dans une revue inserm-00550723v1
In Silico Studies on DARC. Alexandre de Brevern,Ludovic Autin,Yves Colin,Olivier Bertrand,Catherine Etchebest Infectious disorders drug targets, 2009, 9 (3), pp.289-303 Article dans une revue inserm-00366309v1
Analyzing the sequence-structure relationship of a library of local structural prototypes. Cristina Benros,Alexandre de Brevern,Serge A. Hazout Journal of Theoretical Biology, 2009, 256 (2), pp.215-26. ⟨10.1016/j.jtbi.2008.08.032⟩ Article dans une revue inserm-00318954v1
Computational fragment-based drug design to explore the hydrophobic sub-pocket of the mitotic kinesin Eg5 allosteric binding site. Ksenia Oguievetskaia,Laetitia Martin-Chanas,Artem Vorotyntsev,Olivia Doppelt-Azeroual,Xavier Brotelet al. Journal of Computer-Aided Molecular Design, 2009, 23 (8), pp.571-82. ⟨10.1007/s10822-009-9286-z⟩ Article dans une revue inserm-00396557v1
Analysis of protein chameleon sequence characteristics. Amine Ghozlane,Agnel Joseph,Aurélie Bornot,Alexandre de Brevern Bioinformation, 2009, 3 (9), pp.367-9 Article dans une revue inserm-00353122v1
Protein short loop prediction in terms of a structural alphabet. Manoj Tyagi,Aurélie Bornot,Bernard Offmann,Alexandre de Brevern Computational Biology and Chemistry, 2009, 33 (4), pp.329-33. ⟨10.1016/j.compbiolchem.2009.06.002⟩ Article dans une revue inserm-00396485v1
Editorial for Infectious Diseases - Drug Targets (in silico issue) Alexandre de Brevern Infectious disorders drug targets, 2009, 9 (3), pp.246-7 Article dans une revue inserm-00395256v1
A new prediction strategy for long local protein structures using an original description. Aurélie Bornot,Catherine Etchebest,Alexandre de Brevern Proteins - Structure, Function and Bioinformatics, 2009, 76 (3), pp.570-87. ⟨10.1002/prot.22370⟩ Article dans une revue inserm-00348740v1
Analysis of protein contacts into Protein Units. Guilhem Faure,Aurélie Bornot,Alexandre de Brevern Biochimie, 2009, 91 (7), pp.876-87. ⟨10.1016/j.biochi.2009.04.008⟩ Article dans une revue inserm-00375095v1
Analysis of HSP90-related folds with MED-SuMo classification approach. Olivia Doppelt-Azeroual,Fabrice Moriaud,François Delfaud,Alexandre de Brevern Drug Design, Development and Therapy, 2009, 3, pp.59-72 Article dans une revue inserm-00348737v1
Analysis of loop boundaries using different local structure assignment methods. Manoj Tyagi,Aurélie Bornot,Bernard Offmann,Alexandre de Brevern Protein Science, 2009, 18 (9), pp.1869-81. ⟨10.1002/pro.198⟩ Article dans une revue inserm-00392504v1
Protein contacts, inter-residue interactions and side-chain modelling. Guilhem Faure,Aurélie Bornot,Alexandre de Brevern Biochimie, 2008, 90 (4), pp.626-39. ⟨10.1016/j.biochi.2007.11.007⟩ Article dans une revue inserm-00189828v1
In silico local structure approach: A case study on Outer Membrane Proteins. Juliette Martin,Alexandre de Brevern,Anne-Claude Camproux Proteins - Structure, Function and Bioinformatics, 2008, 71 (1), pp.92-109. ⟨10.1002/prot.21659⟩ Article dans une revue inserm-00176452v1
How flexible protein structures are? New questions on the protein structure plasticity. Aurélie Bornot,Bernard Offmann,Alexandre de Brevern BioForum Europe, 2007, 11, pp.24 Article dans une revue inserm-00189079v1
Local Protein Structures Bernard Offmann,Manoj Tyagi,Alexandre de Brevern Current Bioinformatics, 2007, 2, pp.165-202 Article dans une revue inserm-00175058v1
Protein structure mining using a structural alphabet. Manoj Tyagi,Alexandre de Brevern,Narayanaswamy Srinivasan,Bernard Offmann Proteins - Structure, Function and Bioinformatics, 2007, 71 (2), pp.920-937. ⟨10.1002/prot.21776⟩ Article dans une revue istex inserm-00176443v1
A reduced amino acid alphabet for understanding and designing protein adaptation to mutation. Catherine Etchebest,Cristina Benros,Aurélie Bornot,Anne-Claude Camproux,Alexandre de Brevern European Biophysics Journal, 2007, 36 (8), pp.1059-69. ⟨10.1007/s00249-007-0188-5⟩ Article dans une revue istex inserm-00155390v1
Pinning strategy&quot;: a novel approach for predicting the backbone structure in terms of protein blocks from sequence. Alexandre de Brevern,Catherine Etchebest,Cristina Benros,Serge A. Hazout Journal of Biosciences, 2007, 32 (1), pp.51-70 Article dans une revue inserm-00143368v1
Functional annotation strategy for protein structures Olivia Doppelt,Fabrice Moriaud,Aurélie Bornot,Alexandre de Brevern Bioinformation, 2007, 1 (9), pp.357-359 Article dans une revue inserm-00143366v1
Protein beta-turn assignments. Aurélie Bornot,Alexandre de Brevern Bioinformation, 2006, 1 (5), pp.153-5 Article dans une revue inserm-00133658v1
Assessing a novel approach for predicting local 3D protein structures from sequence. Cristina Benros,Alexandre de Brevern,Catherine Etchebest,Serge A. Hazout Proteins - Structure, Function and Bioinformatics, 2006, 62 (4), pp.865-80. ⟨10.1002/prot.20815⟩ Article dans une revue istex inserm-00133180v1
A substitution matrix for structural alphabet based on structural alignment of homologous proteins and its applications. Manoj Tyagi,Venkataraman S. Gowri,Narayanaswamy Srinivasan,Alexandre de Brevern,Bernard Offmann Proteins - Structure, Function and Bioinformatics, 2006, 65 (1), pp.32-9. ⟨10.1002/prot.21087⟩ Article dans une revue istex inserm-00133760v1
Protein Peeling': an approach for splitting a 3D protein structure into compact fragments. Jean-Christophe Gelly,Alexandre de Brevern,Serge A. Hazout Bioinformatics, 2006, 22 (2), pp.129-33. ⟨10.1093/bioinformatics/bti773⟩ Article dans une revue inserm-00133725v1
Protein Peeling 2: a web server to convert protein structures into series of protein units. Jean-Christophe Gelly,Catherine Etchebest,Serge A. Hazout,Alexandre de Brevern Nucleic Acids Research, 2006, 34 (Web Server issue), pp.W75-8. ⟨10.1093/nar/gkl292⟩ Article dans une revue inserm-00133731v1
Protein Block Expert (PBE): a web-based protein structure analysis server using a structural alphabet. Manoj Tyagi,Priyanka Sharma,C. S. Swamy,Frédéric Cadet,N. Srinivasanet al. Nucleic Acids Research, 2006, 34 (Web Server issue), pp.W119-23. ⟨10.1093/nar/gkl199⟩ Article dans une revue inserm-00133751v1
A structural alphabet for local protein structures: improved prediction methods. Catherine Etchebest,Cristina Benros,Serge A. Hazout,Alexandre de Brevern Proteins - Structure, Function and Bioinformatics, 2005, 59 (4), pp.810-27. ⟨10.1002/prot.20458⟩ Article dans une revue istex inserm-00143564v1
Protein secondary structure assignment revisited: a detailed analysis of different assignment methods. Juliette Martin,Guillaume Letellier,Antoine Marin,Jean-François Taly,Alexandre de Brevernet al. BMC Structural Biology, 2005, 5 (17), pp.17. ⟨10.1186/1472-6807-5-17⟩ Article dans une revue inserm-00090199v1
A structural model of a seven-transmembrane helix receptor: the Duffy antigen/receptor for chemokine (DARC). Alexandre de Brevern,H. Wong,Christophe Tournamille,Yves Colin,Caroline Le van Kimet al. BBA - Biochimica et Biophysica Acta, 2005, 1724 (3), pp.288-306. ⟨10.1016/j.bbagen.2005.05.016⟩ Article dans une revue inserm-00143373v1
New assessment of a structural alphabet. Alexandre de Brevern In Silico Biol, 2005, 5 (3), pp.283-9 Article dans une revue inserm-00132875v1
Influence of microarrays experiments missing values on the stability of gene groups by hierarchical clustering. Alexandre de Brevern,Serge A. Hazout,Alain Malpertuy BMC Bioinformatics, 2004, 5, pp.114. ⟨10.1186/1471-2105-5-114⟩ Article dans une revue inserm-00000113v1
Local backbone structure prediction of proteins. Alexandre de Brevern,Cristina Benros,Romain Gautier,Hélène Valadié,Serge A. Hazoutet al. In Silico Biology, 2004, 4 (3), pp.381-6 Article dans une revue inserm-00132872v1
Use of a structural alphabet for analysis of short loops connecting repetitive structures. Laurent Fourrier,Cristina Benros,Alexandre de Brevern BMC Bioinformatics, 2004, 5, pp.58. ⟨10.1186/1471-2105-5-58⟩ Article dans une revue inserm-00112104v1
Hybrid protein model' for optimally defining 3D protein structure fragments. Alexandre de Brevern,Serge A. Hazout Bioinformatics, 2003, 19 (3), pp.345-53. ⟨10.1093/bioinformatics/btf859⟩ Article dans une revue inserm-00133632v1
Genome compartimentation by a hybrid chromosome model (HXM). Application to Saccharomyces cerevisae subtelomeres Alexandre de Brevern,France Loirat,Anne Badel-Chagnon,Cécile André,Pierre Vincenset al. Computers and Chemistry, 2002, 26 (5), pp.437-45. ⟨10.1016/S0097-8485(02)00006-2⟩ Article dans une revue istex inserm-00143383v1
Compartimentation chromosomique Alexandre de Brevern Biofutur, 2002, 225, pp.20-22 Article dans une revue inserm-00132826v1
Extension of a local backbone description using a structural alphabet: a new approach to the sequence-structure relationship. Alexandre de Brevern,Hélène Valadié,Serge A. Hazout,Catherine Etchebest Protein Science, 2002, 11 (12), pp.2871-86 Article dans une revue inserm-00143374v1
Compacting local protein folds with a Hybrid Protein Alexandre de Brevern,Serge A. Hazout Theoretical Chemistry Accounts: Theory, Computation, and Modeling, 2001, 106 (1/2), pp.36-47. ⟨10.1007/s002140000227⟩ Article dans une revue istex inserm-00132867v1
Exploring the use of a structural alphabet for a structural prediction of protein loops Anne-Claude Camproux,Alexandre de Brevern,Serge A. Hazout,Pierre Tufféry Theoretical Chemistry Accounts: Theory, Computation, and Modeling, 2001, 106 (1/2), pp.28-35. ⟨10.1007/s002140100261⟩ Article dans une revue istex inserm-00134555v1
Bayesian probabilistic approach for predicting backbone structures in terms of protein blocks. Alexandre de Brevern,Catherine Etchebest,Serge A. Hazout Proteins - Structure, Function and Bioinformatics, 2000, 41 (3), pp.271-87 Article dans une revue inserm-00132821v1

Communication dans un congrès (9)

Structural and sequence investigations of regioselectivity and substrate specificity in a family of enzymes: the case study of ubiquinone biosynthesis hydroxylases Elin Teppa,Romain Launay,Alexandre de Brevern,William Schmitt,Ivan Junieret al. Journées du GDR Bioinformatique Moléculaire, GT MASIM, Nov 2021, Lyon, France Communication dans un congrès hal-04785151v1
Analysis of allosteric effect of pathologic variants at the light of local protein conformations Alexandre de Brevern Belgrade BioInformatics Conference – BelBi 2018, Jun 2018, Belgrade, Serbia Communication dans un congrès inserm-01853665v1
Protein structure analysis, prediction and flexibility in the light of a structural alphabet Alexandre de Brevern 1ère réunion du GT MASIM du GDR BIM, GDR BIM (CNRS), Nov 2017, Paris, France Communication dans un congrès inserm-01636581v1
Dynamics and deformability of α-, 310- and π-helices Nicolas Shinada,Tarun Jairaj Narwani,Pierrick Craveur,Hubert Santuz,Joseph Rebehmedet al. 20e congrès du GGMM (groupe de graphisme et modélisation moléculaire), May 2017, Reims, France Communication dans un congrès inserm-01581259v1
PB-PENTAdb : a web resource for the analysis and prediction of local backbone structure and flexibility using pentapeptide protein blocks Bernard Offmann,M. Tyagi,A. Joseph,M. Drula,M. Grondinet al. 9th European Congress on Computation Biology (ECCB10), Sep 2010, Ghent, Belgium Communication dans un congrès hal-01198468v1
Hybrid Protein Model (HPM) : A Method For Building A Library Of Overlapping Local Structural Prototypes. Sensitivity Study And Improvements Of The Training Cristina Benros,Alexandre de Brevern,Serge Hazout 2003, pp.53-72 Communication dans un congrès inserm-00133639v1
Hybrid Protein Model&quot;: a new clustering approach for 3D local structures Cristina Benros,Serge A. Hazout,Alexandre de Brevern 2002, pp.36-45 Communication dans un congrès inserm-00134559v1
Hybrid Protein Model (HPM)&quot; : une nouvelle approche pour caractériser les relations séquence-structure dans les protéines Alexandre de Brevern,Serge A. Hazout 2000, pp.105-112 Communication dans un congrès inserm-00134567v1
Hybrid Protein Model (HPM): a method to compact protein 3D-structures information and physicochemical properties. Alexandre de Brevern,Serge A. Hazout 2000, pp.49-54, ⟨10.1109/SPIRE.2000.878179⟩ Communication dans un congrès inserm-00132863v1

Poster de conférence (7)

Analysis of the interaction of cannabinoids with their human CNR1 and CNR2 receptors. Hanine Kaddour,Yahadih Yacob Ahmed,Linda Sgorbini,Pascal Doppelt,Julien Diharceet al. XXIVème congrès du Groupe de Graphisme et Modélisation Moléculaire (GGMM), Jun 2025, Forges-Les-Eaux, France Poster de conférence inserm-05384147v1
Analyse par dynamiques moléculaires de 5 types de Calréticuline associée à la thrombocytémie essentielle Ragousandirane Radjasandirane,Alexandre de Brevern 43e congrès de la Société Française d'Hématologie, Mar 2024, Paris, France Poster de conférence inserm-04072440v1
Evaluation of 50 Computational Tools for Predicting Pathogenicity of Genetic Variants: Unveiling representativeness issues on public datasets Ragousandirane Radjasandirane,Jean-Christophe Gelly,Julien Diharce,Alexandre de Brevern International Symposium on Human Genomics, Sep 2023, Paris, France Poster de conférence hal-04264309v1
Analysis of VHH dynamics Akhila Melarkode Vattekatte,Julien Diharce,Catherine Etchebest,Alexandre de Brevern 67th Biophysical Society Annual Meeting, Feb 2023, San Diego (California), United States Poster de conférence inserm-04072706v1
On the turning away Alexandre de Brevern 20e congrès du GGMM (groupe de graphisme et modélisation moléculaire), Aug 2017, Reims, France. 2017 Poster de conférence inserm-01575727v1
On the turning away Alexandre de Brevern Joint 25th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB) and 16th European Conference on Computational Biology (ECCB) 2017, Aug 2017, Prague, Czech Republic. , 2017 Poster de conférence inserm-01575565v1
Comparative Analysis of Protein -Protein Interface Methods Alexandre de Brevern,Jérémy Esque Groupe Graphisme Modélisation Moléculaire (GGMM), May 2017, Reims, France Poster de conférence inserm-01586501v1

Ouvrages (1)

Bioinformatique - 3e édition Gilbert Deléage,Manolo Gouy,Alexandre de Brevern Dunod, 2021, Collection Sciences Sup, 978-2-10-081515-9 Ouvrages hal-03356596v1

Chapitre d'ouvrage (9)

Modélisation des systèmes biologiques, bioinformatique Olivier Gascuel,P. Benas,C. Brun,D. Burnouf,Alexandre de Brevernet al. Rapport de conjoncture 2010 du Comité national de la recherche scientifique, CNRS Editions, chapitre 43, 845-858, 2011, 978-2-271-07263-4 Chapitre d'ouvrage hal-00799641v1
A bioinformatic web server to cut protein structures in terms of Protein Units. Jean-Christophe Gelly,Alexandre de Brevern Jaclyn E. Morris. Computer Science Research and the Internet, Nova Book Press, pp.169-183, 2011 Chapitre d'ouvrage inserm-00646177v1
Local Structure Alphabets Agnel Joseph,Aurélie Bornot,Alexandre de Brevern Huzefa Rangwala, George Karypis. Introduction to Protein Structure Prediction: Methods and Algorithms, Wiley, pp.75-106, 2010, ⟨10.1002/9780470882207.ch5⟩ Chapitre d'ouvrage inserm-00557300v1
Characterization of Conformational Patterns in Active and Inactive Forms of Kinases Using Protein Blocks Approach. Garima Agarwal,Dhurvas Chandrasekaran Dinesh,Narayanaswamy Srinivasan,Alexandre de Brevern Ujjwal Maulik, Sanghamitra Bandyopadhyay, Jason T. L. Wang. Computational Intelligence and Pattern Analysis in Biological Informatics, Wiley, pp.169-188, 2010, ⟨10.1002/9780470872352.ch8⟩ Chapitre d'ouvrage inserm-00557296v1
Turns prediction Patrick Fuchs,Catherine Etchebest,Alexandre de Brevern Alexandre G. de Brevern. Recent Advances in Structural Bioinformatics, Research Signpost, Trivandrum, Kerala, India., pp.43-63, 2007 Chapitre d'ouvrage inserm-00176710v1
Description of the local protein structure. I. Classical approaches. Cristina Benros,Juliette Martin,Manoj Tyagi,Alexandre de Brevern Alexandre G. de Brevern. Recent Advances in Structural Bioinformatics, Research Signpost, Trivandrum, Kerala, India., pp.6-27, 2007 Chapitre d'ouvrage inserm-00176471v1
Description of the local protein structure. II. Novel approaches. Manoj Tyagi,Cristina Benros,Juliette Martin,Alexandre de Brevern Alexandre G. de Brevern. Recent Advances in Structural Bioinformatics, Research Signpost, Trivandrum, Kerala, India., pp.28-42, 2007 Chapitre d'ouvrage inserm-00176668v1
Structural Alphabet: From a Local Point of View to a Global Description of Protein 3D Structures Alexandre de Brevern,Cristina Benros,Serge A. Hazout Yan, Peter V. Bioinformatics: New Research, Nova publishers, pp.127-69, 2005 Chapitre d'ouvrage inserm-00134564v1
Protein structural alphabets: beyond the secondary structure description Alexandre de Brevern,Anne-Claude Camproux,Serge A. Hazout,Catherine Etchebest,Pierre Tufféry Sangadai SG. Recent research developments in protein engineering, Research signpost, pp.319-331, 2001 Chapitre d'ouvrage inserm-00133650v1

Pré-publication, Document de travail (1)

PEPOP: new approaches to mimic non-continous epitopes Vincent Demolombe,Alexandre de Brevern,Liza Felicori,Christophe Nguyen,Ricardo Andrez Machado de Avilaet al. 2018 Pré-publication, Document de travail (preprint/prepublication) hal-02787634v1

Thèse (1)

Nouvelles stratégies d'analyses et de prédiction des structures tridimensionnelles des protéines Alexandre de Brevern Biochimie [q-bio.BM]. Université Paris-Diderot - Paris VII, 2001. Français. ⟨NNT : ⟩ Thèse tel-00133819v1