Alexandre DESTERE

Publications

Article dans une revue (30)

Artificial intelligence to guide rituximab therapy in patients with phospholipase A2 receptor–associated membranous nephropathy Maxime Teisseyre,Alexandre Destere,Marion Cremoni,Sonia Boyer-Suavet,Alexandre Karaméet al. Clinical Kidney Journal, 2025, 18 (5), ⟨10.1093/ckj/sfaf113⟩ Article dans une revue hal-05155985v1
Artificial intelligence-based personalised rituximab treatment protocol in membranous nephropathy (iRITUX): protocol for a multicentre randomised control trial Maxime Teisseyre,Alexandre Destere,Marion Cremoni,Kévin Zorzi,Vesna Brglezet al. BMJ Open, 2025, 15 (4), pp.e093920. ⟨10.1136/bmjopen-2024-093920⟩ Article dans une revue hal-05155978v1
Therapeutic Drug Monitoring of Long-Acting Cabotegravir and Rilpivirine in a National Cohort of People With Human Immunodeficiency Virus Type 1: First Results From the ANRS-MIE CARLAPOP Study Nadège Néant,Minh Lê,Stéphane Bouchet,Jennifer Lagoutte-Renosi,Matthieu Grégoireet al. Clinical Infectious Diseases, 2025, pp.ciaf385. ⟨10.1093/cid/ciaf385⟩ Article dans une revue hal-05240572v1
A new chapter in pharmacology: Artificial intelligence's expanding role in pharmacokinetics, pharmacodynamics, and pharmacovigilance Alexandre O Gérard,Romain Lombardi,Diane Merino,Charles Bouveyron,Jean Dellamonicaet al. Therapies, In press, ⟨10.1016/j.therap.2025.09.002⟩ Article dans une revue hal-05397772v1
Maximum cold ischemia duration for a kidney allograft: a prediction model for allograft failure at the time of organ allocation Clement Gosset,Susana Barbosa,Alexandre Destere,Sebastien Cuozzo,Laetitia Albanoet al. EClinicalMedicine, 2025, 85, pp.103322. ⟨10.1016/j.eclinm.2025.103322⟩ Article dans une revue hal-05251430v1
Impact of epinephrine on ropivacaine pharmacokinetics in TAP blocks: a randomized controlled trial Romain Rozier,Yann Le Guennec,Xavier Capdevila,Eric Le Louarn,Juliette Balboet al. Regional Anesthesia and Pain Medicine, 2025, 16 (3), rapm-2025-106500. ⟨10.1136/rapm-2025-106500⟩ Article dans une revue hal-05155972v1
Polyintoxication with cenobamate, perampanel, and carbamazepine: A complex case report Alexandre Destere,Alexandre Gérard,Diane Merino,Elliot Ewig,Fanny Rocheret al. Therapies, 2025, 80 (3), pp.351-354. ⟨10.1016/j.therap.2024.12.001⟩ Article dans une revue hal-04981201v1
Large-Scale Real-World Monitoring of Mycophenolic Acid Exposure in Liver Transplantation: Impact of Bayesian Dose Adjustment Marc Labriffe,Hamza Sayadi,Jean-Baptiste Woillard,Ludovic Micallef,Franck Saint-Marcouxet al. Therapeutic Drug Monitoring, 2025, ⟨10.1097/FTD.0000000000001377⟩ Article dans une revue hal-05251447v1
Evaluating and leveraging large language models in clinical pharmacology and therapeutics assessment: From exam takers to exam shapers Alexandre Gérard,Diane Merino,Marc Labriffe,Fanny Rocher,Delphine Viardet al. British Journal of Clinical Pharmacology, 2025, ⟨10.1002/bcp.70137⟩ Article dans une revue hal-05155988v1
Safety profile of belatacept in a real-life setting: disproportionality analysis of the WHO pharmacovigilance database Alexandre Gérard,Diane Merino,Nouha Ben Othman,Alexandre Destere,Delphine Viardet al. BMC Pharmacology and Toxicology, 2025, 26 (1), pp.147. ⟨10.1186/s40360-025-00972-6⟩ Article dans une revue hal-05251433v1
A Machine Learning Algorithm to Predict the Starting Dose of Daptomycin Florence Rivals,Sylvain Goutelle,Cyrielle Codde,Romain Garreau,Laure Ponthieret al. Clinical Pharmacokinetics, 2024, 63 (8), ⟨10.1007/s40262-024-01405-z⟩ Article dans une revue hal-04666577v1
An artificial intelligence algorithm for co‐clustering to help in pharmacovigilance before and during the COVID‐19 pandemic Alexandre Destere,Giulia Marchello,Diane Merino,Nouha Ben Othman,Alexandre Gérardet al. British Journal of Clinical Pharmacology, 2024, 90 (5), pp.1258-1267. ⟨10.1111/bcp.16012⟩ Article dans une revue hal-04660639v1
A case of lenacapavir use for preventing mother-to-child HIV transmission Victor Hémar,Stéphane Bouchet,Emmanuel Ribeiro,Perrine Prier,Christophe Elleauet al. Journal of Antimicrobial Chemotherapy, In press, ⟨10.1093/jac/dkae348⟩ Article dans une revue hal-04753282v1
Cardiac and metabolic safety profile of antipsychotics in youths: A WHO safety database analysis Diane Merino,Alexandre Gérard,Alexandre Destere,Haitam Saidessalam,Florence Askenazyet al. Psychiatry Research, 2024, 334, pp.115786. ⟨10.1016/j.psychres.2024.115786⟩ Article dans une revue hal-04660641v1
A Plasma Pyrophosphate Cutoff Value for Diagnosing Pseudoxanthoma Elasticum Isabelle Rubera,Laetitia Clotaire,Audrey Laurain,Alexandre Destere,Ludovic Martinet al. International Journal of Molecular Sciences, 2024, 25 (12), pp.6502. ⟨10.3390/ijms25126502⟩ Article dans une revue hal-04660679v1
Deep dynamic co-clustering of count data streams: application to pharmacovigilance Giulia Marchello,Alexandre Destere,Marco Corneli,Charles Bouveyron Journal of Data Science, Statistics, and Visualisation, 2024, 4 (4), ⟨10.52933/jdssv.v4i4.106⟩ Article dans une revue hal-04395096v1
To be or not to be, when synthetic data meet clinical pharmacology: A focused study on pharmacogenetics Jean‐baptiste Woillard,Clément Benoist,Alexandre Destere,Marc Labriffe,Giulia Marchelloet al. CPT: Pharmacometrics and Systems Pharmacology, 2024, Online ahead of print. ⟨10.1002/psp4.13240⟩ Article dans une revue hal-04747078v1
A machine learning approach to predict daptomycin exposure from two concentrations based on Monte Carlo simulations Cyrielle Codde,Florence Rivals,Alexandre Destere,Yeleen Fromage,Marc Labriffeet al. Antimicrobial Agents and Chemotherapy, 2024, 68 (5), ⟨10.1128/aac.01415-23⟩ Article dans une revue hal-04660675v1
Tacrolimus population pharmacokinetics in adult heart transplant patients Adrien Paschier,Alexandre Destere,Caroline Monchaud,Marc Labriffe,Pierre Marquetet al. British Journal of Clinical Pharmacology, 2023, ⟨10.1111/bcp.15857⟩ Article dans une revue hal-04189142v1
Iatrogenic triggers for anorexia nervosa and bulimia nervosa: A WHO safety database disproportionality analysis Diane Merino,Alexandre Olivier Gérard,Alexandre Destere,Florence Askenazy,Emmanuelle Doret al. Psychiatry Research, 2023, 327, pp.115415. ⟨10.1016/j.psychres.2023.115415⟩ Article dans une revue hal-04189150v1
Optimization of Rituximab Therapy in Adult Patients With PLA2R1-Associated Membranous Nephropathy With Artificial Intelligence Alexandre Destere,Maxime Teisseyre,Diane Merino,Marion Cremoni,Alexandre Gérardet al. Kidney International Reports, In press, ⟨10.1016/j.ekir.2023.10.023⟩ Article dans une revue hal-04321277v1
A Hybrid Algorithm Combining Population Pharmacokinetic and Machine Learning for Isavuconazole Exposure Prediction Alexandre Destere,Pierre Marquet,Marc Labriffe,Milou-Daniel Drici,Jean-Baptiste Woillard Pharmaceutical Research, 2023, 40 (4), pp.951-959. ⟨10.1007/s11095-023-03507-y⟩ Article dans une revue hal-04414322v1
The Neuropsychiatric Safety Profile of Lasmiditan: A Comparative Disproportionality Analysis with Triptans Diane Merino,Alexandre Gérard,Elise van Obberghen,Alexandre Destere,Michel Lanteri-Minetet al. Neurotherapeutics, 2023, ⟨10.1007/s13311-023-01404-1⟩ Article dans une revue hal-04189133v1
Drug-induced cardiac toxicity and adverse drug reactions, a narrative review Alexandre Destere,Diane Merino,Thibaud Lavrut,Fanny Rocher,Delphine Viardet al. Therapies, 2023, ⟨10.1016/j.therap.2023.10.008⟩ Article dans une revue hal-04321284v1
Optimization of Vancomycin Initial Dose in Term and Preterm Neonates by Machine Learning Laure Ponthier,Pauline Ensuque,Alexandre Destere,Pierre Marquet,Marc Labriffeet al. Pharmaceutical Research, 2022, 39 (10), pp.2497-2506. ⟨10.1007/s11095-022-03351-6⟩ Article dans une revue hal-04414340v1
A Hybrid Model Associating Population Pharmacokinetics with Machine Learning: A Case Study with Iohexol Clearance Estimation Alexandre Destere,Pierre Marquet,Charlotte Salmon Gandonnière,Anders Åsberg,Véronique Loustaud-Rattiet al. Clinical Pharmacokinetics, 2022, 61 (8), pp.1157-1165. ⟨10.1007/s40262-022-01138-x⟩ Article dans une revue hal-04414345v1
A Machine Learning Approach to Estimate the Glomerular Filtration Rate in Intensive Care Unit Patients Based on Plasma Iohexol Concentrations and Covariates Jean-Baptiste Woillard,Charlotte Salmon Gandonnière,Alexandre Destere,Stephan Ehrmann,Hamid Merdjiet al. Clinical Pharmacokinetics, 2021, 60, pp.223-233. ⟨10.1007/s40262-020-00927-6⟩ Article dans une revue hal-04414374v1
New 8-Nitroquinolinone Derivative Displaying Submicromolar in Vitro Activities against Both Trypanosoma brucei and cruzi Julien Pedron,Clotilde Boudot,Jean-Yves Brossas,Emilie Pinault,Sandra Bourgeade-Delmaset al. ACS Medicinal Chemistry Letters, 2020, 11 (4), pp.464-472. ⟨10.1021/acsmedchemlett.9b00566⟩ Article dans une revue hal-02476867v1
8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi Cyril Fersing,Clotilde Boudot,Caroline Castera-Ducros,Émilie Pinault,Sébastien Hutteret al. European Journal of Medicinal Chemistry, 2020, 202, pp.112558. ⟨10.1016/j.ejmech.2020.112558⟩ Article dans une revue hal-02899751v1
Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T. b. brucei hit-compound with improved pharmacokinetic properties Cyril Fersing,Clotilde Boudot,Romain Paoli-Lombardo,Nicolas Primas,Emilie Pinaultet al. European Journal of Medicinal Chemistry, 2020, 206, pp.112668. ⟨10.1016/j.ejmech.2020.112668⟩ Article dans une revue hal-02920293v1

Thèse (1)

Suivi du patient transplanté rénal traité par tacrolimus par pharmacocinétique de population et machine learning Alexandre Destere Médecine humaine et pathologie. Université de Limoges, 2022. Français. ⟨NNT : 2022LIMO0109⟩ Thèse tel-04402665v1