AMEL BAHLOUL

Publications

Poster de conférence (1)

Excitotoxicity induced synaptopathy: From molecular mechanisms to targeted therapies. Anissa Rym Saidia,Florence François,Jérôme Ruel,François Casas,Amel Bahloulet al. 46. Annual MidWinter Meeting of Association for Research in Otolaryngology, Feb 2023, Orlando, United States Poster de conférence hal-04903030v1

Article dans une revue (21)

Current Advances in Gene Therapies of Genetic Auditory Neuropathy Spectrum Disorder Anissa Rym Saidia,Jérôme Ruel,Amel Bahloul,Benjamin Chaix,Frédéric Venailet al. Journal of Clinical Medicine, 2023, 12 (3), pp.738. ⟨10.3390/jcm12030738⟩ Article dans une revue (article de synthèse) hal-04311297v1
Ultrarare heterozygous pathogenic variants of genes causing dominant forms of early-onset deafness underlie severe presbycusis Sophie Boucher,Fabienne Wong Jun Tai,Sedigheh Delmaghani,Andrea Lelli,Amrit Singh-Estivaletet al. Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (49), pp.31278-31289. ⟨10.1073/pnas.2010782117⟩ Article dans une revue pasteur-03215054v1
Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners Yanlei Zhu,Florent Delhommel,Florence Cordier,Susanne Lüchow,Ariel E Mechalyet al. Journal of Molecular Biology, 2020, 432 (22), pp.5920 - 5937. ⟨10.1016/j.jmb.2020.09.012⟩ Article dans une revue hal-02990253v1
A Novel Heterozygous Missense Variant (c.667G&gt;T;p.Gly223Cys) in USH1C That Interferes With Cadherin-Related 23 and Harmonin Interaction Causes Autosomal Dominant Nonsyndromic Hearing Loss Ju Sun Song,Amel Bahloul,Christine Petit,Sang Jin Kim,Il Joon Moonet al. Annals of Laboratory Medicine, 2020, 40 (3), pp.224-231. ⟨10.3343/alm.2020.40.3.224⟩ Article dans une revue hal-02433812v1
Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells Vincent Michel,Elise Pepermans,Jacques Boutet de Monvel,Patrick England,Sylvie Nouailleet al. Scientific Reports, 2020, 10 (1), pp.16430. ⟨10.1038/s41598-020-73158-1⟩ Article dans une revue hal-02988089v1
CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival Vincent Michel,Kevin T Booth,Pranav Patni,Matteo Cortese,Hela Azaiezet al. EMBO Molecular Medicine, 2017, 9 (12), pp.1711 - 1731. ⟨10.15252/emmm.201708087⟩ Article dans une revue hal-01661175v1
Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses Nicolas Michalski,Juan D Goutman,Sarah Marie Auclair,Jacques Boutet de Monvel,Margot Tertraiset al. eLife, 2017, 6, pp.e31013. ⟨10.7554/eLife.31013⟩ Article dans une revue hal-01665122v1
Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem Florent Delhommel,Florence Cordier,Benjamin Bardiaux,Guillaume Bouvier,Baptiste Colcombet-Cazenaveet al. Structure, 2017, 25 (11), pp.1645-1656.e5. ⟨10.1016/j.str.2017.08.013⟩ Article dans une revue pasteur-02883914v1
Conformational switch of harmonin, a submembrane scaffold protein of the hair cell mechanoelectrical transduction machinery Amel Bahloul,Elise Pepermans,Bertrand Raynal,Nicolas Wolff,Florence Cordieret al. FEBS Letters, 2017, 591 (15), pp.2299 - 2310. ⟨10.1002/1873-3468.12729⟩ Article dans une revue pasteur-01858477v1
Diversity of the Genes Implicated in Algerian Patients Affected by Usher Syndrome Samia Abdi,Amel Bahloul,Asma Behlouli,Jean-Pierre Hardelin,Mohamed Makreloufet al. PLoS ONE, 2016, 11 (9), pp.e0161893. ⟨10.1371/journal.pone.0161893⟩ Article dans une revue hal-01388303v1
The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells Elise Pepermans,Vincent Michel,Richard Goodyear,Crystel Bonnet,Samia Abdiet al. EMBO Molecular Medicine, 2014, 6 (7), pp.984-992. ⟨10.15252/emmm.201403976⟩ Article dans une revue pasteur-01237053v1
Crystal Structure of Two Anti-Porphyrin Antibodies with Peroxidase Activity Victor Muñoz Robles,Jean-Didier Maréchal,Amel Bahloul,Marie-Agnès Sari,Jean-Pierre Mahyet al. PLoS ONE, 2012, 7 (12), pp.e51128. ⟨10.1371/journal.pone.0051128⟩ Article dans une revue hal-03280278v1
Localization of Usher 1 proteins to the photoreceptor calyceal processes, which are absent from mice Iman Sahly,Eric Dufour,Cataldo Schietroma,Vincent Michel,Amel Bahloulet al. Journal of Cell Biology, 2012, 199 (2), pp.381-399. ⟨10.1083/jcb.201202012⟩ Article dans une revue inserm-00743698v1
Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia. Elisa Caberlotto,Michel Vittot,Isabelle Foucher,Amel Bahloul,Richard J Goodyearet al. Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (14), pp.5825-30. ⟨10.1073/pnas.1017114108⟩ Article dans une revue pasteur-01472844v1
Cadherin-23, myosin VIIa and harmonin, encoded by Usher syndrome type I genes, form a ternary complex and interact with membrane phospholipids Amel Bahloul,Vincent Michel,Jean-Pierre Hardelin,Sylvie Nouaille,Sylviane Hooset al. Human Molecular Genetics, 2010, 19 (18), pp.3557 - 3565. ⟨10.1093/hmg/ddq271⟩ Article dans une revue pasteur-03525648v1
Myosin VI is required for the proper maturation and function of inner hair cell ribbon synapses Isabelle Roux,Suzanne Hosie,Stuart Johnson,Amel Bahloul,Nadège Cayetet al. Human Molecular Genetics, 2009, 18 (23), pp.4615-4628. ⟨10.1093/hmg/ddp429⟩ Article dans une revue hal-04159601v1
Vezatin, an integral membrane protein of adherens junctions, is required for the sound resilience of cochlear hair cells. Amel Bahloul,Marie-Christine Simmler,Vincent Michel,Michel Leibovici,Isabelle Perfettiniet al. EMBO Molecular Medicine, 2009, 1 (2), pp.125-38. ⟨10.1002/emmm.200900015⟩ Article dans une revue hal-00477439v1
Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Isabelle Roux,Saaid Safieddine,Régis Nouvian,M'Hamed Grati,Marie-Christine Simmleret al. Cell, 2006, 127 (2), pp.277-89. ⟨10.1016/j.cell.2006.08.040⟩ Article dans une revue hal-00111976v1
Electrospray ionization mass spectrometry studies of noncovalent myosin VI complexes reveal a new specific calmodulin binding site Guillaume Chevreux,Noelle Potier,Alain Dorsselaer,Amel Bahloul,Anne Houdusseet al. Journal of The American Society for Mass Spectrometry, 2005, 16 (8), pp.1367-1376. ⟨10.1016/j.jasms.2005.03.023⟩ Article dans une revue istex hal-02981194v1
PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIa. Raphael Etournay,Aziz El-Amraoui,Amel Bahloul,Stéphane Blanchard,Isabelle Rouxet al. Journal of Cell Science, 2005, 118 (13), pp.2891-99. ⟨10.1242/jcs.02424⟩ Article dans une revue pasteur-01541848v1
Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle Batiste Boëda,Aziz El-Amraoui,Amel Bahloul,Richard Goodyear,Laurent Davietet al. EMBO Journal, 2002, 21 (24), pp.6689-6699. ⟨10.1093/emboj/cdf689⟩ Article dans une revue pasteur-05017570v1

Chapitre d'ouvrage (1)

Chapter 11 Myosin VII Aziz El-Amraoui,Amel Bahloul,Christine Petit Lynne M. Coluccio. Myosins. A Superfamily of Molecular Motors, Springer, pp. 353-373, 2008, 978-1-4020-6516-3. ⟨10.1007/978-1-4020-6519-4_11⟩ Chapitre d'ouvrage pasteur-05026397v1