Amelie Bernard CRCN, group leader at the Laboratory of Membrane Biogenesis, UMR5200 CNRS, University of Bordeaux

Identifiants chercheurs

IdHAL :

amelie-bernard

ORCID :

0000-0001-7073-2440

IdRef :

157438902

VIAF :

289388227

Présentation

Dr Amélie BernardBorn January 5, 1984 in Saint-Lô, Manche

HDR, Accreditation to direct research University of Bordeaux (2023)Doctor in plant biology from University of Bordeaux (2011)

Current positionCRCN, group leader at the Laboratory of Membrane Biogenesis, UMR5200 CNRS, University of Bordeaux*Exploring the nature, dynamics and function of lipids in membrane remodelling during plant autophagy and their importance in plant adaptation programs to environmental stress *

Higher studies2008 - Master in Plant Biology, University of Bordeaux, France2008-2011 - PhD thesis in plant biology, University of Bordeaux, France2011-2012 - Postdoctorate in plant biology, Laboratory of Membrane Biogenesis, CNRS, University of Bordeaux, France2012-2016 - Post-doctorate in cell biology, Klionsky Laboratory, Life Sciences Institute, University of Michigan, Ann Arbor, USA

Research activities2016 -&gt;: Research Scientist (CR) and group leader (Laboratory of Membrane Biogenesis, CNRS, University of Bordeaux;2012-2016: Post-doctorate in cell biology, Klionsky Laboratory, Life Sciences Institute, University of Michigan, Ann Arbor, USACharacterization of novel actors and signalling pathways involved in the regulation of autophagy-related genes in S. cerevisiae2011-2012: Post-doctorate at the Laboratory of Membrane Biogenesis, CNRS, University of Bordeaux, FranceStudy of the ECERIFERUM proteins involved in very-long-chain alkane synthesis in Arabidopsis2008-2011: Thesis at the Laboratory of Membrane Biogenesis, CNRS, University of Bordeaux, FranceCharacterization of the alkane-forming pathway in Arabidopsis

Research supervisionGroup leader since 2016. Current group composed of 1 researcher, 1 PhD student, 1 lecturer, 2 research engineers, 2 assistant engineers, 1 technician (in 2024).PhD supervision: 2Post-docs supervision: 1Master supervision: 7Undergraduate student supervision: 3

Publications33 in peer review journalsOral communications at scientific conferences: 19

Prizes and Rewards2023: CNRS Bronze Medal

Editorial experience2023-&gt; Associate editor in Frontiers in Plant Physiology

Major contracts and research funding obtained2022 – 2024 Emerging project AutoLip2 (How autophagy reshapes lipid metabolism to promote plant acclimation to environmental changes, Idex CNRS/UB), Coordinator, 85k€2021 – 2025 Associated investigator of ANR RecovOil (Plant lipid droplets in post-stress recovery; ANR AAPG2021), 450k€2020 – 2025 ERC Starting Grant (The missing link: how do membrane lipids interplay with ATG proteins to instruct plant autophagy, LIP-ATG, 852136) Coordinator, 1.5M€2018 – 2020 Seed Fund AutoLip1 (Lipids function in plant autophagy, Idex CNRS/UB), Coordinator, 30k€2018 – 2019 Seed fund Fédération de Recherche BIE. Co-coordinator, 7k€2017 – 2021 Salary for a PhD student, UB, 90 K€

Publications

Pré-publication, Document de travail (4)

Monitoring and methods for estimating the biodiversity of a watercourse in an alpine ecosystem by metabarcoding analyses Amélie Bernard,Augustin Maniouloux,Clémentine Capitaine,Florian Petrilli,Ibtissam Dichet al. 2026 Pré-publication, Document de travail hal-05495981v1
Clathrin-coated vesicles are targeted for selective autophagy during osmotic stress Jonathan Michael Dragwidge,Matthieu Buridan,Julia Kraus,Thibault Kosuth,Clément Chambaudet al. 2025 Pré-publication, Document de travail hal-05375768v1
Unveiling the molecular identity of plant autophagic compartments: A proteo-lipidomic study in &lt;i&gt;Arabidopsis thaliana&lt;/i&gt; Josselin Lupette,Clément Chambaud,Matthieu Buridan,Julie Castets,Valérie Wattelet-Boyeret al. 2025 Pré-publication, Document de travail hal-05367204v1
A dual component system instructs membrane hydrolysis during the final stages of plant autophagy Julie Castets,Matthieu Buridan,Inés Toboso Moreno,Víctor Sánchez de Medina Hernández,Rodrigo Enrique Gomezet al. 2025 Pré-publication, Document de travail hal-05375770v1

Communication dans un congrès (14)

The phospholipases LCAT3 and LCAT4 are key players in the final stages of autophagy in Arabidopsis Julie Castets,Matthieu Buridan,Rodrigo Enrique Gomez,Franziska Dittrich-Domergue,Josselin Lupetteet al. Plant Proteolysis (GRS) Gordon Research Semina "Proteolysis During Plant Development and Stress Responses", Jan 2025, Lucca, Italy Communication dans un congrès hal-05279370v1
Lipid/protein interplay in membrane formation and remodeling during plant autophagy Julie Castets,Josselin Lupette,Matthieu Buridan,Inés Toboso Moreno,Clément Chambaudet al. Jacques Monod Conference Molecular basis for membrane remodelling and organisation, May 2025, Roscoff, France Communication dans un congrès hal-05283163v1
Lipid/protein interplay in membrane formation and remodeling during plant autophagy Julie Castets,Josselin Lupette,Matthieu Buridan,Clément Chambaud,Inés Toboso Morenoet al. Saclay Plant Sciences seminars, Jan 2025, Versailles, France Communication dans un congrès hal-05283108v1
Lipid/protein interplay in membrane formation and remodeling during plant autophagy Julie Castets,Josselin Lupette,Matthieu Buridan,Inés Toboso Moreno,Clément Chambaudet al. 12th Scientific days on autophagy, Mar 2025, Nice, France Communication dans un congrès hal-05283121v1
Lipid/protein interplay in membrane remodeling during plant autophagy Julie Castets,Josselin Lupette,Matthieu Buridan,Inés Toboso Moreno,Victor Sánchez de Medina Hernándezet al. 20th GERLI International Lipid Meeting, Nov 2025, Strasbourg, France Communication dans un congrès hal-05283052v1
Deciphering the singularity of autophagic membranes: key lipids in autophagy Josselin Lupette,Clément Chambaud,Céline Yatim,Franziska Dittrich-Domergue,Marguerite Batsaleet al. 2025 Gordon Research Seminar, Jan 2025, Lucca, Italy Communication dans un congrès hal-05279385v1
Lipid/protein interplay in membrane formation and remodeling during plant autophagy Amélie Bernard,Josselin Lupette,Julie Castets,Clément Chambaud,Matthieu Buridanet al. 26th International Plant Molecular Biology (IPMB 2024), Jun 2024, Cairns, Australia Communication dans un congrès hal-05279320v1
Lipid/protein interplay in membrane formation and remodeling during plant autophagy Julie Castets,Josselin Lupette,Matthieu Buridan,Inés Toboso Moreno,Clément Chambaudet al. International Plant Proteostasis Conference, Sep 2024, Vienne, Austria Communication dans un congrès hal-05279334v1
AtVPS13M1 is involved in lipid remodeling in response to phosphate starvation and is located to mitochondria in Arabidopsis thaliana Sébastien Leterme,Catherine Albrieux,Yohann Couté,Sabine Brugière,Benjamin Gilletet al. International Conference on Plant Mitochondria Biology, May 2024, Saint-Malo, France Communication dans un congrès hal-04852503v1
LCAT3 and LCAT4: dual key players in the final stages of autophagy in Arabidopsis Julie Castets,Matthieu Buridan,Rodrigo Enrique Gomez,Franziska Dittrich-Domergue,Josselin Lupetteet al. 14th International Congress of the French Society of Plant Biology, Jun 2024, Bordeaux, France Communication dans un congrès hal-05279307v1
How do membrane lipids contribute to autophagy in plants ? Rodrigo Enrique Gomez,Clément Chambaud,Josselin Lupette,Julie Castets,Stéphanie Pascalet al. ENPER 2023 - 23rd European Network for Plant Endomembrane Research, Oct 2023, Constance, Germany Communication dans un congrès hal-05274098v1
The molecular signature of autophagic structures in Arabidopsis thaliana Josselin Lupette,Clément Chambaud,Céline Yatim,Valérie Gros,Juliette Jouhetet al. 2nd French Membrane Meeting Workshop, Sep 2023, Bordeaux, France Communication dans un congrès hal-05274065v1
Molecular cartography of purified autophagic membranes to decrypt autophagosome formation in Arabidopsis thaliana Josselin Lupette,Clément Chambaud,Céline Yatim,Valérie Gros,Juliette Jouhetet al. ESPL 2023 - 10th European Symposium on Plant Lipids, Jul 2023, Amsterdam, Netherlands Communication dans un congrès hal-05274047v1
Unravelling the contribution of lipids in plant autophagy Josselin Lupette,Clément Chambaud,Julie Castets,Céline Yatim,Valérie Groset al. Plant Membrane Club, Jun 2022, Lyon, France Communication dans un congrès hal-05273812v1

Article dans une revue (19)

Chaperone-mediated autophagy in fish: A key function amid a changing environment Simon Schnebert,Emilio J. Vélez,Maxime Goguet,Karine Dias,Vincent Veronet al. Autophagy Reports, 2024, 3 (1), ⟨10.1080/27694127.2024.2403956⟩ Article dans une revue hal-04794731v1
Biomolecular condensation orchestrates clathrin-mediated endocytosis in plants Jonathan Michael Dragwidge,Yanning Wang,Lysiane Brocard,Andreas de Meyer,Roman Hudečeket al. Nature Cell Biology, 2024, 26 (3), pp.438-449. ⟨10.1038/s41556-024-01354-6⟩ Article dans une revue hal-04680984v1
HOPping to the vacuole: Autophagosome and late endosomes combine to control plant autophagosome degradation Jonathan Michael Dragwidge,Amélie Bernard Developmental Cell, 2024, 59 (17), pp.2273-2274. ⟨10.1016/j.devcel.2024.08.005⟩ Article dans une revue hal-04794740v1
Targeting Ultrastructural Events at the Graft Interface of Arabidopsis thaliana by A Correlative Light Electron Microscopy Approach Clément Chambaud,Sarah J. Cookson,Nathalie Ollat,Amélie Bernard,Lysiane Brocard Bio-protocol , 2023, 13 (2), pp.e4590. ⟨10.21769/bioprotoc.4590⟩ Article dans une revue hal-04297913v1
Phosphatidylinositol-4-phosphate controls autophagosome formation in Arabidopsis thaliana Rodrigo Enrique Gomez,Clément Chambaud,Josselin Lupette,Julie Castets,Stéphanie Pascalet al. Nature Communications, 2022, 13 (1), pp.4385. ⟨10.1038/s41467-022-32109-2⟩ Article dans une revue hal-03774766v1
SETD2 transcriptional control of ATG14L/S isoforms regulates autophagosome–lysosome fusion Patricia Gonzalez-Rodriguez,Elizabeth Delorme-Axford,Amélie Bernard,Lily Keane,Vassilis Stratouliaset al. Cell Death and Disease, 2022, 13 (11), pp.1-13. ⟨10.1038/s41419-022-05381-9⟩ Article dans une revue hal-03957390v1
Phosphatidylinositol-4-phosphate joins the dance of plant autophagosome formation Rodrigo Enrique Gomez,Julie Castets,Josselin Lupette,Clément Chambaud,Jérôme Joubèset al. Autophagy, 2022, 19, pp.1609 - 1610. ⟨10.1080/15548627.2022.2132042⟩ Article dans une revue hal-04297803v1
AtEH/Pan1 proteins drive phase separation of the TPLATE complex and clathrin polymerisation during plant endocytosis Jonathan Michael Dragwidge,Yanning Wang,Lysiane Brocard,Andreas de Meyer,Roman Hudečeket al. BioRxiv, 2022, ⟨10.1101/2022.03.17.484738⟩ Article dans une revue hal-03847415v1
Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer Yuanyuan Qiao,Jae Eun Choi,Jean Tien,Stephanie Simko,Thekkelnaycke Rajendiranet al. Nature Cancer, 2021, 2 (9), pp.978-993. ⟨10.1038/s43018-021-00237-1⟩ Article dans une revue hal-03440254v1
How Lipids Contribute to Autophagosome Biogenesis, a Critical Process in Plant Responses to Stresses Rodrigo Enrique Gomez,Josselin Lupette,Clément Chambaud,Julie Castets,Amélie Ducloyet al. Cells, 2021, 10 (6), pp.1272. ⟨10.3390/cells10061272⟩ Article dans une revue hal-03883291v1
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) Daniel Klionsky,Amal Kamal Abdel-Aziz,Sara Abdelfatah,Mahmoud Abdellatif,Asghar Abdoliet al. Autophagy, 2021, 17 (1), pp.1-382. ⟨10.1080/15548627.2020.1797280⟩ Article dans une revue (article de synthèse) inserm-03285572v1
Arabidopsis CER1-LIKE1 Functions in a Cuticular Very-Long-Chain Alkane-Forming Complex 1 Stéphanie Pascal,Amélie Bernard,Paul Deslous,Julien Gronnier,Ashley Fournier-Gosset al. Plant Physiology, 2019, 179 (2), pp.415-432. ⟨10.1104/pp.18.01075⟩ Article dans une revue hal-02368049v1
Lipids in membrane dynamics during autophagy in plants Rodrigo Enrique Gomez,Jérôme Joubès,Nicolas Valentin,Henri Batoko,Béatrice Satiat-Jeunemaîtreet al. Journal of Experimental Botany, 2018, 69 (6), pp.1287--1299. ⟨10.1093/jxb/erx392⟩ Article dans une revue hal-02177909v1
A novel pathway of targeted autophagy is induced by DNA damage in budding yeast Vinay Eapen,David Waterman,Amélie Bernard,Nathan Schiffman,Enrich Sayaset al. Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (7), pp.E1158-E1167. ⟨10.1073/pnas.1614364114⟩ Article dans une revue hal-03156537v1
Arabidopsis cuticular waxes: Advances in synthesis, export and regulation Amelie Bernard,Jérôme Joubès Progress in Lipid Research, 2013, 52 (1), pp.110 - 129. ⟨10.1016/j.plipres.2012.10.002⟩ Article dans une revue istex hal-02651423v1
The Arabidopsis cer26 mutant, like the cer2 mutant, is specifically affected in the very long chain fatty acid elongation process Stéphanie Pascal,Amélie Bernard,Maud Sorel,Marjorie Pervent,Denis Vileet al. The Plant Journal, 2013, 73 (5), pp.733-746. ⟨10.1111/tpj.12060⟩ Article dans une revue hal-02643891v1
Reconstitution of Plant Alkane Biosynthesis in Yeast Demonstrates That Arabidopsis ECERIFERUM1 and ECERIFERUM3 Are Core Components of a Very-Long-Chain Alkane Synthesis Complex Amelie Bernard,Frederic Domergue,Stephanie Pascal,Reinhard Jetter,Charlotte Renneet al. The Plant cell, 2012, 24 (7), pp.3106 - 3118. ⟨10.1105/tpc.112.099796⟩ Article dans une revue hal-01003414v1
Overexpression of Arabidopsis ECERIFERUM1 promotes wax very-long-chain alkane biosynthesis and influences plant response to biotic and abiotic stresses Brice Bourdenx,Amelie Bernard,Frederic Domergue,Stéphanie Pascal,Amandine Legeret al. Plant Physiology, 2011, 156 (1), pp.29-45. ⟨10.1104/pp.111.172320⟩ Article dans une revue hal-02651224v1
The Impact of Water Deficiency on Leaf Cuticle Lipids of Arabidopsis Dylan K Kosma,Brice Bourdenx,Amélie Bernard,Eugene P Parsons,Shiyou Lüet al. Plant Physiology, 2009, 151 (4), pp.1918 - 1929. ⟨10.1104/pp.109.141911⟩ Article dans une revue hal-05190097v1

Poster de conférence (6)

Phosphatidylinositol-4-phosphate controls autophagosome formation in Arabidopsis thaliana Rodrigo Enrique Gomez,Clément Chambaud,Josselin Lupette,Julie Castets,Stéphanie Pascalet al. Gordon Research Conference / Plant Lipids: Structure, Metabolism and Function, Jan 2023, Galveston - Texas, United States Poster de conférence hal-05273955v1
FUNCTIONAL CHARACTERIZATION OF AN ATYPICAL PHOSPHOLIPASES FAMILY AT THE CROSSTALK BETWEEN LIPID METABOLISM AND AUTOPHAGY IN ARABIDOPSIS Julie Castets,Josselin Lupette,Clément Chambaud,Franziska Dittrich-Domergue,Rodrigo Enrique Gomezet al. 23rd Meeting of the European Network for Plant Endomembrane Research (ENPER 2023), Sep 2023, Constance, Germany Poster de conférence hal-05115133v1
Phosphatidylinositol-4-phosphate controls autophagosome formation in Arabidopsis thaliana Clément Chambaud,Rodrigo E Gomez,Julie Castets,Stéphanie Pascal,Lysiane Brocardet al. 32nd International Conference on Arabidopsis Research ICAR2022, Jun 2022, Belfast, Ireland Poster de conférence hal-05273826v1
Establishing the molecular signature of autophagic membranes to decrypt autophagosome formation in Arabidopsis thaliana Josselin Lupette,Clément Chambaud,Julie Castets,Céline Yatim,Valérie Groset al. ISPL 2022 - 25th International Symposium on Plant Lipids, Jul 2022, Grenoble, France Poster de conférence hal-05273858v1
FUNCTIONAL CHARACTERIZATION OF A PROTEIN IN THE CROSSTALK BETWEEN LIPID METABOLISM AND AUTOPHAGY IN ARABIDOPSIS Julie Castets,Josselin Lupette,Clément Chambaud,Rodrigo Enrique Gomez,Yasin Dagdaset al. International Symposium of Plant Lipid, Jun 2022, Grenoble, France Poster de conférence hal-05115106v1
FUNCTIONAL CHARACTERIZATION OF A PROTEIN IN THE CROSSTALK BETWEEN LIPID METABOLISM AND AUTOPHAGY IN ARABIDOPSIS Julie Castets,Josselin Lupette,Clément Chambaud,Rodrigo Enrique Gomez,Yasin Dagdaset al. Groupe d'Etude et de Recherche sur les Lipides, Sep 2021, Bordeaux, France Poster de conférence hal-05115009v1