Anne Astier CV Anne Astier

Publications

Article dans une revue (39)

Sex Bias in IL-10 Production by Type I Regulatory T Cells Regulated by PI3K/mTOR Signaling Aymeline Debonlier,Saniya Kari,Florence Bucciarelli,Thibault Angles,Amelia Perez-Pestelet al. Neurology Neuroimmunology & Neuroinflammation, 2026, 13 (2), ⟨10.1212/NXI.0000000000200532⟩ Article dans une revue hal-05495698v1
In vitro morphological profiling of T cells predicts clinical response to natalizumab therapy in patients with multiple sclerosis Beatriz Chaves,Juan Carlo Santos E Silva,Helder Nakaya,Nicolas Socquet-Juglard,Florence Bucciarelliet al. Nature Communications, 2025, 16 (1), pp.5533. ⟨10.1038/s41467-025-60224-3⟩ Article dans une revue inserm-05373591v1
Increased levels of circulating soluble CD226 in multiple sclerosis Saniya Kari,Florence Bucciarelli,Thibault Angles,Anne-Cecile Oster,Pauline Cauboueet al. Multiple Sclerosis Journal, 2024, 30 (6), pp.654-663. ⟨10.1177/13524585241234489⟩ Article dans une revue hal-04759633v1
Impact of the Multiple Sclerosis-Associated Genetic Variant CD226 Gly307Ser on Human CD8 T-Cell Functions Elena Morandi,Véronique Adoue,Isabelle Bernard,Ekaterina Friebel,Nicolas Nunezet al. Neurology Neuroimmunology & Neuroinflammation, 2024, 11 (6), pp.e200306. ⟨10.1212/NXI.0000000000200306⟩ Article dans une revue hal-04780777v1
Editorial: Dysregulation of Th17 and Treg cells in autoimmune diseases Anne Astier,David M Kofler Frontiers in Immunology, 2023, 14, pp.1151836. ⟨10.3389/fimmu.2023.1151836⟩ Article dans une revue hal-04040545v1
Full spectrum of vitamin D immunomodulation in multiple sclerosis: mechanisms and therapeutic implications Manon Galoppin,Saniya Kari,Sasha Soldati,Arindam Pal,Manon Rivalet al. Brain Communications, 2022, 4 (4), pp.fcac171. ⟨10.1093/braincomms/fcac171⟩ Article dans une revue (article de synthèse) hal-03795617v1
Immune complex-induced apoptosis and concurrent immune complex clearance are anti-inflammatory neutrophil functions Utsa Karmakar,Julia Chu,Kruthika Sundaram,Anne Laurence Astier,Hannah Garsideet al. Cell Death and Disease, 2021, 12, pp.296. ⟨10.1038/s41419-021-03528-8⟩ Article dans une revue hal-03365812v1
Vitamin D/CD46 Crosstalk in Human T Cells in Multiple Sclerosis Justin Killick,Joanne Hay,Elena Morandi,Sonja Vermeren,Saniya Kariet al. Frontiers in Immunology, 2020, ⟨10.3389/fimmu.2020.598727⟩ Article dans une revue hal-03021917v1
A Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites Barry Mccormick,Helen Craig,Julia Chu,Leo Carlin,Marta Canelet al. Journal of Immunology, 2019, 203 (6), pp.1579-1588. ⟨10.4049/jimmunol.1900443⟩ Article dans une revue hal-02321910v1
The anthelmintic drug praziquantel promotes human Tr1 differentiation Enwono Eyoh,Patrick Mccallum,Justin Killick,Seth Amanfo,Francisca Mutapiet al. Immunology and Cell Biology, 2019, 97 (5), pp.512-518. ⟨10.1111/imcb.12229⟩ Article dans une revue hal-02321954v1
Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis Calum Robb,Henry Mcsorley,Jinju Lee,Tomohiro Aoki,Cunjing Yuet al. Journal of Allergy and Clinical Immunology, 2018, 141 (1), pp.152-162. ⟨10.1016/j.jaci.2017.04.045⟩ Article dans une revue hal-02322314v1
Nitric oxide induces human CLA + CD25 + Foxp3 + regulatory T cells with skin-homing potential Cunjing Yu,Amanda Fitzpatrick,Duanduan Cong,Chengcan Yao,Jinah Yooet al. Journal of Allergy and Clinical Immunology, 2017, 140 (5), pp.1441-1444.e6. ⟨10.1016/j.jaci.2017.05.023⟩ Article dans une revue hal-02322054v1
Complement as a regulator of adaptive immunity Justin Killick,Gregoire Morisse,Dirk Sieger,Anne Astier Seminars in Immunopathology, 2017, Epub ahead of print. ⟨10.1007/s00281-017-0644-y⟩ Article dans une revue inserm-01593213v1
HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33 Megan Osbourn,Dinesh Soares,Francesco Vacca,E. Suzanne Cohen,Ian C. Scottet al. Immunity, 2017, 47 (4), pp.739-751.e5. ⟨10.1016/j.immuni.2017.09.015⟩ Article dans une revue hal-02322026v1
TCR-stimulated changes in cell surface CD46 expression generate type 1 regulatory T cells Siobhan Ni Choileain,Joanne Hay,Joëlle Thomas,Anna Williams,Matthieu Vermerenet al. Science Signaling, 2017, 10 (502), pp.eaah6163. ⟨10.1126/scisignal.aah6163⟩ Article dans une revue hal-02322005v1
Preclinical safety, pharmacokinetics, pharmacodynamics, and biodistribution studies with Ad35K++ protein: a novel rituximab cotherapeutic Maximilian Richter,Roma Yumul,Kamola Saydaminova,Hongjie Wang,Michael Goughet al. Molecular Therapy - Methods and Clinical Development, 2016, 3, pp.16013. ⟨10.1038/mtm.2016.13⟩ Article dans une revue hal-02322334v1
Editorial: T Cell Regulation by the Environment David A Hafler,Anne Astier Frontiers in Immunology, 2015, 6, ⟨10.3389/fimmu.2015.00229⟩ Article dans une revue hal-02322088v1
Recombinant Ad35 adenoviral proteins as potent modulators of human T-cell activation Joanne Hay,Darrick Carter,André Lieber,Anne Astier Immunology, 2015, 144 (3), pp.453-460. ⟨10.1111/imm.12391⟩ Article dans une revue hal-02322119v1
Monocyte:T-cell interaction regulates human T-cell activation through a CD28/CD46 crosstalk Lauren Charron,Axelle Doctrinal,Siobhan Ni Choileain,Anne Astier Immunology and Cell Biology, 2015, 93 (9), pp.796-803. ⟨10.1038/icb.2015.42⟩ Article dans une revue hal-02322105v1
CD46 processing: A means of expression Siobhan Ni Choileain,Anne Astier Immunobiology, 2012, 217 (2), pp.169-175. ⟨10.1016/j.imbio.2011.06.003⟩ Article dans une revue hal-02322194v1
Prostaglandin E 2 Affects T Cell Responses through Modulation of CD46 Expression Karoline Kickler,Kathryn Maltby,Siobhán Ni Choileain,Jillian Stephen,Sheila Wrightet al. Journal of Immunology, 2012, 188 (11), pp.5303-5310. ⟨10.4049/jimmunol.1103090⟩ Article dans une revue hal-02322163v1
Calcitriol Modulates the CD46 Pathway in T Cells Karoline Kickler,Siobhan Ni Choileain,Anna Williams,Anna Richards,Anne Astier PLoS ONE, 2012, 7 (10), pp.e48486. ⟨10.1371/journal.pone.0048486⟩ Article dans une revue hal-02322141v1
The Dynamic Processing of CD46 Intracellular Domains Provides a Molecular Rheostat for T Cell Activation Siobhan Ni Choileain,Nathan Weyand,Christian Neumann,Joëlle Thomas,Magdalene Soet al. PLoS ONE, 2011, 6 (1), pp.e16287. ⟨10.1371/journal.pone.0016287⟩ Article dans une revue hal-02322210v1
CD46 Plasticity and Its Inflammatory Bias in Multiple Sclerosis Siobhan Ni Choileain,Anne Astier Archivum Immunologiae et Therapiae Experimentalis, 2011, 59 (1), pp.49-59. ⟨10.1007/s00005-010-0109-7⟩ Article dans une revue hal-02322224v1
RNA Interference Screen in Primary Human T Cells Reveals FLT3 as a Modulator of IL-10 Levels Anne Astier,Gaëlle Bériou,Thomas Eisenhaure,Stephen Anderton,David A Hafleret al. Journal of Immunology, 2010, 184 (2), pp.685-693. ⟨10.4049/jimmunol.0902443⟩ Article dans une revue hal-02322245v1
Association of the Cas-like Molecule HEF1 with CrkL Following Integrin and Antigen Receptor Signaling in Human B-Cells: Potential Relevance to Neoplastic Lymphohematopoietic Cells Anne Astier,Serge Manie,Susan Law,Timothy Canty,Nilou Haghayghiet al. Leukemia & lymphoma, 2009, 28 (1-2), pp.65-72. ⟨10.3109/10428199709058332⟩ Article dans une revue hal-02322508v1
T-cell regulation by CD46 and its relevance in multiple sclerosis Anne Astier Immunology, 2008, 124 (2), pp.149-154. ⟨10.1111/j.1365-2567.2008.02821.x⟩ Article dans une revue hal-02322284v1
Increased IL-23 secretion and altered chemokine production by dendritic cells upon CD46 activation in patients with multiple sclerosis Adi Vaknin-Dembinsky,Gopal Murugaiyan,David A Hafler,Anne Astier,Howard Weiner Journal of Neuroimmunology, 2008, 195 (1-2), pp.140-145. ⟨10.1016/j.jneuroim.2008.01.002⟩ Article dans une revue hal-02322265v1
Abnormal Tr1 differentiation in multiple sclerosis Anne Astier,David A Hafler Journal of Neuroimmunology, 2007, 191 (1-2), pp.70-78. ⟨10.1016/j.jneuroim.2007.09.018⟩ Article dans une revue hal-02322361v1
Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis Anne Astier,Grégory Meiffren,Samuel Freeman,David A Hafler Journal of Clinical Investigation, 2006, 116 (12), pp.3252-3257. ⟨10.1172/JCI29251⟩ Article dans une revue hal-02322380v1
Integrins regulate survival of pre-B-ALL cells through differential IAP and caspase-7 ubiquitination and degradation Anne Astier,M. Svoboda,E Hinds,R de Beaumont,O Munozet al. Leukemia, 2004, 18 (4), pp.873-875. ⟨10.1038/sj.leu.2403298⟩ Article dans une revue hal-02322390v1
TGFβ-mediated activation of Smad1 in B-cell non-Hodgkin's lymphoma and effect on cell proliferation O Munoz,F Fend,R de Beaumont,H Husson,Anne Astieret al. Leukemia, 2004, 18 (12), pp.2015-2025. ⟨10.1038/sj.leu.2403485⟩ Article dans une revue hal-02322468v1
Temporal gene expression profile of human precursor B leukemia cells induced by adhesion receptor: identification of pathways regulating B-cell survival Anne Astier,Anne Laurence Astier,Ronghui Xu,Marek Svoboda,Esther Hindset al. Blood, 2003, 101 (3), pp.1118-1127. ⟨10.1182/blood-2002-05-1519⟩ Article dans une revue hal-02322406v1
Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell–induced inflammation Julien C. Marie,Anne Astier,Pierre Rivailler,Chantal Rabourdin-Combe,T. Fabian Wildet al. Nature Immunology, 2002, 3 (7), pp.659-666. ⟨10.1038/ni810⟩ Article dans une revue istex hal-02322420v1
CD46/CD3 Costimulation Induces Morphological Changes of Human T Cells and Activation of Vav, Rac, and Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Yona Zaffran,Olivier Destaing,Agnès Roux,Stéphane Ory,Thao Nheuet al. Journal of Immunology, 2001, 167 (12), pp.6780-6785. ⟨10.4049/jimmunol.167.12.6780⟩ Article dans une revue hal-02322447v1
Regulation of Integrin-mediated p130 Cas Tyrosine Phosphorylation in Human B Cells Serge Manie,Anne Astier,Nilou Haghayeghi,Timothy Canty,Brian Drukeret al. Journal of Biological Chemistry, 1997, 272 (25), pp.15636-15641. ⟨10.1074/jbc.272.25.15636⟩ Article dans une revue hal-02322529v1
The Related Adhesion Focal Tyrosine Kinase Differentially Phosphorylates p130 Cas and the Cas-like Protein, p105 HEF1 Anne Astier,Serge Manie,Hava Avraham,Hisamaru Hirai,Susan Lawet al. Journal of Biological Chemistry, 1997, 272 (32), pp.19719-19724. ⟨10.1074/jbc.272.32.19719⟩ Article dans une revue hal-02322522v1
Involvement of p130 Cas and p105 HEF1 , a Novel Cas-like Docking Protein, in a Cytoskeleton-dependent Signaling Pathway Initiated by Ligation of Integrin or Antigen Receptor on Human B Cells Serge Manie,Andreas R.P. Beck,Anne Astier,Susan Law,Tim Cantyet al. Journal of Biological Chemistry, 1997, 272 (7), pp.4230-4236. ⟨10.1074/jbc.272.7.4230⟩ Article dans une revue hal-02322550v1
The Related Adhesion Focal Tyrosine Kinase Is Tyrosine-phosphorylated after β1-Integrin Stimulation in B Cells and Binds to p130 cas Anne Astier,Hava Avraham,Serge Manie,Jerome Groopman,Timothy Cantyet al. Journal of Biological Chemistry, 1997, 272 (1), pp.228-232. ⟨10.1074/jbc.272.1.228⟩ Article dans une revue hal-02322564v1

Communication dans un congrès (1)

Role of vitamin D and CD226 in a T cell regulatory pathway altered in MS Saniya Kari,Thibault Angles,Elena Morandi,David Frieser,Abdelhadi Saoudiet al. 6th European Congress of Immunology, Sep 2021, Virtual meeting, France. pp.144, ⟨10.1002/eji.202170200⟩ Communication dans un congrès hal-04979442v1

Pré-publication, Document de travail (3)

The multiple sclerosis associated CD226 risk variant alters vitamin D-induced human type I regulatory T cell differentiation by impairing LFA-1 activation Anne Laurence Astier,Saniya Kari,Aymeline Debonlier,Thibault Angles,Beatriz Chaveset al. 2025 Pré-publication, Document de travail hal-05083602v1
Morphological profiling of T cells predicts clinical response to VLA-4-targeting natalizumab therapy in patients with multiple sclerosis Beatriz Chaves,Juan Carlo Santos E Silva,Helder Nakaya,Matheus Almeida,Florence Bucciarelliet al. 2024 Pré-publication, Document de travail inserm-04728349v1
CITE-seq reveals inhibition of NF-κB pathway in B cells from vitamin D-treated multiple sclerosis patients Manon Galoppin,Manon Rival,Anaïs Louis,Saniya Kari,Sasha Soldatiet al. 2023 Pré-publication, Document de travail (preprint/prepublication) hal-04241503v1