Anne Harduin-Lepers

Publications

Communication dans un congrès (8)

Diversity and evolution of the vertebrate sialyltransferase repertoire. Anne Harduin-Lepers EUROCARB22, Pr. Zbigniew Kaczyński, Jul 2025, Gdansk, Poland Communication dans un congrès hal-05404028v1
Diversity and evolution of the vertebrate sialyltransferase repertoire Anne Harduin-Lepers Glyco27-8th Canadian Glycomics Symposium, Pr. Matthew Macauley, May 2025, Edmonton (Alberta), Canada Communication dans un congrès hal-05403910v1
Molecular and functional evolution of vertebrate sialyltransferases Anne Harduin-Lepers SIALOGLYCO 2024, Dr. Yann GUERARDEL, Jun 2024, Lille, France Communication dans un congrès hal-05403866v1
Molecular and functional evolution of vertebrate α2,8-sialyltransferases (ST8SIA) Anne Harduin-Lepers SIALOGLYCO 2022, Pr. Ken KITAJIMA Pr. Hideharu ISHIDA Pr. Chihiro SATO, Sep 2022, Nagoya, Japan Communication dans un congrès hal-05403826v1
Variations of sialyltransferase ST6Gal2 gene regulation in mammals. Benoît B. Laporte,Severine Lehoux,Daniel Petit,S. Groux-Degroote,Abderrahman A. Maftahet al. 13th Evolutionary Biology Meeting, 2009, Marseille, pp.Inconnu Communication dans un congrès hal-02822983v1
Phylogenetic and evolutionary analysis of animal sialyltransferases. Daniel Petit,Jean-Michel Petit,R. Mollicone,P. Delannoy,R. Oriolet al. 13th Evolutionary Biology Meeting, 2009, Marseille, pp.Inconnu Communication dans un congrès hal-02813871v1
Phylogenetic and evolutionary analysis of animal sialyltransferases: a focus on the ST8Sia family. A. Harduin-Lepers,R. Oriol,R. Mollicone,P. Delannoy,Jean-Michel Petitet al. Glyco-19 : XIX International Symposium on Glycoconjugates. 15-20 July, 2007, Cairns, pp.Inconnu Communication dans un congrès hal-02816832v1
The evolution history of the sialyltransferase genes superfamily. Polysialic Acid: Chemistry, Biology, Translational Aspects. A. Harduin-Lepers,Daniel Petit,R. Mollicone,P. Delannoy,Jean-Michel Petitet al. 3rd International Meeting, 10-13 March, 2007, Inconnu, pp.Inconnu Communication dans un congrès hal-02814500v1

Article dans une revue (102)

Evolutionary analyses of the animal glycosyltransferase family 54 reveals two β1,4-N-acetylglucosaminyltransferase families Aoi Morigo,Roxana Elin Teppa,Masamichi Nagae,Hirokazu Yagi,Yasuhiko Kizukaet al. Iscience, 2025, Iscience, 28 (11), pp.113788. ⟨10.1016/j.isci.2025.113788⟩ Article dans une revue hal-05374661v1
Sialoglycoproteins and sialyltransferases: Key regulators of blastocyst formation Pélagie Douchez,Ingrid Fliniaux,Yoshiko Takeda-Uchimura,Matthieu Marin,Alain Martoriatiet al. Cells & Development, 2025, ⟨10.1016/j.cdev.2025.204057⟩ Article dans une revue hal-05445943v1
Probiotic L. reuteri treatment in stressed rats improves maternal care and corrects corticosterone-BDNF-oxytocin balance offering insights for maternal postpartum distress treatment Ryma Benlakehal,Alessandra Gaetano,Rogatien Charlet,Hammou Bouwalerh,Virginie Cogezet al. Scientific Reports, 2025, 15 (1), pp.23544. ⟨10.1038/s41598-025-05848-7⟩ Article dans une revue hal-05383259v1
Transcription factor FOXD1 and miRNA-204-5p play a major role in B4GALNT2 downregulation in colon cancer Martina Duca,Nadia Malagolini,Michela Pucci,Virginie Cogez,Anne Harduin-Leperset al. Scientific Reports, 2025, Scientific Reports, 15 (1), pp.1821. ⟨10.1038/s41598-025-85450-z⟩ Article dans une revue hal-04906532v1
Adhesion to aggression: unravelling sLea and sLex in cancer metastasis Prasanna H. Megalamani,Anne Harduin-Lepers,J. Manasa,Maruti J. Gurav,Ashwini S. Sanjiet al. Clinical and Experimental Metastasis, 2025, Clinical and Experimental Metastasis, 42 (6), pp.42-58. ⟨10.1007/s10585-025-10378-7⟩ Article dans une revue (article de synthèse) hal-05376277v1
Cadmium induces physiological and behavioral changes associated with 180 kDa NCAM lower expression and higher polysialic acid, in the African clawed Xenopus laevis tadpoles Guillaume Marchand,Ingrid Fliniaux,Pauline Titran,Yoshiko Uchimura,Jean-Francois Bodartet al. Ecotoxicology and Environmental Safety, 2024, Ecotoxicology and Environmental Safety, 273, pp.116119. ⟨10.1016/j.ecoenv.2024.116119⟩ Article dans une revue hal-04674332v1
Regulation of human GnT-IV family activity by the lectin domain Naoko Osada,Masamichi Nagae,Takahiro Yamasaki,Anne Harduin-Lepers,Yasuhiko Kizuka Carbohydrate Research, 2024, Carbohydrate Research, 545, pp.109285. ⟨10.1016/j.carres.2024.109285⟩ Article dans une revue hal-04749515v1
A Rapid and Sensitive MicroPlate Assay (MPSA) Using an Alkyne‐Modified CMP‐Sialic Acid Donor to Evaluate Human Sialyltransferase Specificity Kiamungongo Clairene Filipe,Sushmaa Dangudubiyyam,Cedric Lion,Mathieu Decloquement,Roxana Teppaet al. ChemBioChem, 2024, ChemBioChem, pp.e202400539. ⟨10.1002/cbic.202400539⟩ Article dans une revue hal-04835900v1
LacdiNAc synthase B4GALNT3 has a unique PA14 domain and suppresses N-glycan capping Yuko Tokoro,Masamichi Nagae,Miyako Nakano,Anne Harduin-Lepers,Yasuhiko Kizuka Journal of Biological Chemistry, 2024, Journal of Biological Chemistry, 300 (7), pp.107450. ⟨10.1016/j.jbc.2024.107450⟩ Article dans une revue hal-04628025v1
Molecular dynamics simulations shed light into the donor substrate specificity of vertebrate poly-alpha-2,8-sialyltransferases ST8Sia IV Elin Teppa,Sebastian Peter Galuska,Anne Harduin-Lepers Biochimica et Biophysica Acta (BBA) - General Subjects, 2024, Biochimica et Biophysica Acta (BBA) - General Subjects, 1868 (8), pp.130647. ⟨10.1016/j.bbagen.2024.130647⟩ Article dans une revue hal-04625502v1
Salmonid polysialyltransferases to generate a variety of sialic acid polymers Mathieu Decloquement,Marzia Tindara Venuto,Virginie Cogez,Anna Steinmetz,Celine Schulzet al. Scientific Reports, 2023, Scientific Reports, 13 (1), pp.15610. ⟨10.1038/s41598-023-42095-0⟩ Article dans une revue hal-04220178v1
The vertebrate sialylation machinery: structure-function and molecular evolution of GT-29 sialyltransferases Anne Harduin Lepers Glycoconjugate Journal, 2023, Glycoconjugate Journal, 40 (4), pp.473-492. ⟨10.1007/s10719-023-10123-w⟩ Article dans une revue hal-04221332v1
N-Glycan on the Non-Consensus N-X-C Glycosylation Site Impacts Activity, Stability, and Localization of the Sda Synthase B4GALNT2 Virginie Cogez,Dorothee Vicogne,Celine Schulz,Lucie Portier,Giulia Venturiet al. International Journal of Molecular Sciences, 2023, International Journal of Molecular Sciences, 24 (4), pp.4139. ⟨10.3390/ijms24044139⟩ Article dans une revue hal-04008107v1
Diversity of sialic acids and sialoglycoproteins in gametes and at fertilization Ingrid Fliniaux,Guillaume Marchand,Caroline Molinaro,Mathieu Decloquement,Alain Martoriatiet al. Frontiers in Cell and Developmental Biology, 2022, 10, pp.982931. ⟨10.3389/fcell.2022.982931⟩ Article dans une revue hal-03857419v1
Analysis of the proximal promoter of the human colon-specific B4GALNT2 (Sda synthase) gene: B4GALNT2 is transcriptionally regulated by ETS1 Cindy Wavelet-Vermuse,Sophie Groux-Degroote,Dorothée Vicogne,Virginie Cogez,Giulia Venturiet al. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2021, 1864 (11-12), pp.194747. ⟨10.1016/j.bbagrm.2021.194747⟩ Article dans une revue hal-03345208v1
B4GALNT2 Controls Sd&lt;sup&gt;a&lt;/sup&gt; and SLe&lt;sup&gt;x&lt;/sup&gt; Antigen Biosynthesis in Healthy and Cancer Human Colon Sophie Groux‐degroote,Dorothee Vicogne,Virginie Cogez,Céline Schulz,Anne Harduin‐lepers ChemBioChem, 2021, 22 (24), pp.3381 - 3390. ⟨10.1002/cbic.202100363⟩ Article dans une revue (article de synthèse) hal-04254028v1
Hyposialylation Must Be Considered to Develop Future Therapies in Autoimmune Diseases Anne Bordron,Marie Morel,Cristina Bagacean,Maryvonne Dueymes,Pierre Pochardet al. International Journal of Molecular Sciences, 2021, 22 (7), pp.3402. ⟨10.3390/ijms22073402⟩ Article dans une revue hal-03205737v1
Characterization of the Polysialylation Status in Ovaries of the Salmonid Fish Coregonus maraena and the Percid Fish Sander lucioperca Anne Harduin-Lepers,Marzia Tindara Venuto,Joan Martorell-Ribera,Ralf Bochert,Alexander Reblet al. Cells, 2020, 9 (11), pp.2391. ⟨10.3390/cells9112391⟩ Article dans une revue hal-02998501v1
Vertebrate Alpha2,8-Sialyltransferases (ST8Sia): A Teleost Perspective Marzia Tindara Venuto,Mathieu Decloquement,Joan Martorell Ribera,Maxence Noel,Alexander Reblet al. International Journal of Molecular Sciences, 2020, 21 (2), pp.513. ⟨10.3390/ijms21020513⟩ Article dans une revue hal-02446209v1
A phylogenetic view and functional annotation of the animal β1,3-glycosyltransferases of the GT31 CAZy family Daniel Petit,Roxana Elin Teppa,Anne Harduin-Lepers Glycobiology, 2020, 31 (3), pp.243-259. ⟨10.1093/glycob/cwaa086⟩ Article dans une revue hal-02963114v1
Mycobacterium bovis BCG infection alters the macrophage N -glycome Clément Delannoy,Chin Huang,Bernadette Coddeville,Jian-You Chen,Dounia Mouajjahet al. Molecular Omics, 2020, 16 (4), pp.345-354. ⟨10.1039/c9mo00173e⟩ Article dans une revue hal-03089946v1
Unliganded and CMP-Neu5Ac bound structures of human α-2,6-sialyltransferase ST6Gal I at high resolution Deborah Harrus,Anne Harduin-Lepers,Tuomo Glumoff Journal of Structural Biology, 2020, 212 (2), pp.107628. ⟨10.1016/j.jsb.2020.107628⟩ Article dans une revue hal-02963119v1
Assembly of B4GALT1/ST6GAL1 heteromers in the Golgi membranes involves lateral interactions via highly charged surface domains Fawzi Khoder-Agha,Deborah Harrus,Guillaume Brysbaert,Marc Lensink,Anne Harduin-Leperset al. Journal of Biological Chemistry, 2019, 294 (39), pp.14383-14393. ⟨10.1074/jbc.RA119.009539⟩ Article dans une revue hal-02343482v1
A Golgi-associated redox switch regulates catalytic activation and cooperative functioning of ST6Gal-I with B4GalT-I Antti Hassinen,Fawzi Khoder-Agha,Elham Khosrowabadi,Daniela Mennerich,Deborah Harruset al. Redox Biology, 2019, 24, pp.101182. ⟨10.1016/j.redox.2019.101182⟩ Article dans une revue hal-02297446v1
Glyco25, XXV International Symposium on Glycoconjugates Anne Harduin-Lepers Glycoconjugate Journal, 2019, 36 (4), pp.267-397. ⟨10.1007/s10719-019-09880-4⟩ Article dans une revue hal-02349804v1
Grandma's stress programs transgenerational transmission of hippocampal glutamatergic synaptopathy associated with stress-related responses Sara Morley-Fletcher,Jordan Marrocco,Hélène Léger,Jerome Mairesse,Marie-Line Reynaertet al. Psychoneuroendocrinology, 2019, 107, pp.58. ⟨10.1016/j.psyneuen.2019.07.168⟩ Article dans une revue hal-02349786v1
Novel Zebrafish Mono-α2,8-sialyltransferase (ST8Sia VIII): An Evolutionary Perspective of α2,8-Sialylation Lan-Yi Chang,Elin Teppa,Maxence Noel,Pierre-André Gilormini,Mathieu Decloquementet al. International Journal of Molecular Sciences, 2019, 20 (3), pp.622. ⟨10.3390/ijms20030622⟩ Article dans une revue hal-02095571v1
Roles of GalNAc-disialyl Lactotetraosyl Antigens in Renal Cancer Cells Akiko Tsuchida,Motohiro Senda,Akihiro Ito,Seiichi Saito,Makoto Kisoet al. Scientific Reports, 2018, Scientific Reports, 8 (1), pp.7017. ⟨10.1038/s41598-018-25521-6⟩ Article dans une revue hal-03213011v2
The extended cytoplasmic tail of the human B4GALNT2 is critical for its Golgi targeting and post-Golgi sorting Sophie Groux-Degroote,Céline Schulz,Virginie Cogez,Maxence Noel,Lucie Portieret al. FEBS Journal, 2018, 285 (18), pp.3442-3463. ⟨10.1111/febs.14621⟩ Article dans une revue hal-01867603v1
Systems glycomics of adult zebrafish identifies organ-specific sialylation and glycosylation patterns Nao Yamakawa,Jorick Vanbeselaere,Lan-Yi Chang,Shin-Yi Yu,Lucie Ducrocqet al. Nature Communications, 2018, 9 (1), pp.4647. ⟨10.1038/s41467-018-06950-3⟩ Article dans une revue hal-01931174v1
MicroPlate Sialyltransferase Assay: A Rapid and Sensitive Assay Based on an Unnatural Sialic Acid Donor and Bioorthogonal Chemistry Maxence Noel,Pierre-André Gilormini,Virginie Cogez,Cedric Lion,Christophe Biotet al. Bioconjugate Chemistry, 2018, 29 (10), pp.3377 - 3384. ⟨10.1021/acs.bioconjchem.8b00529⟩ Article dans une revue hal-01931177v1
TNF up-regulates ST3GAL4 and sialyl-Lewisx expression in lung epithelial cells through an intronic ATF2-responsive element. Florent Colomb,Marie-Ange Krzewinski-Recchi,Agata Steenackers,Audrey Vincent,Anne Harduin-Leperset al. Biochemical Journal, 2017, 474 (1), pp.65-78. ⟨10.1042/BCJ20160602⟩ Article dans une revue hal-01429886v1
Reconstruction of the sialylation pathway in the ancestor of eukaryotes Daniel Petit,Elin Teppa,Ugo Cenci,Steven Ball,Anne Harduin-Lepers Scientific Reports, 2017, 8 (1), pp.2946. ⟨10.1038/s41598-018-20920-1⟩ Article dans une revue hal-01741232v1
Probing the CMP-Sialic Acid Donor Specificity of Two Human β- d -Galactoside Sialyltransferases (ST3Gal I and ST6Gal I) Selectively Acting on O- and N-Glycosylproteins Maxence Noel,Pierre-André Gilormini,Virginie Cogez,Nao Yamakawa,Dorothée Vicogneet al. ChemBioChem, 2017, 18 (13), pp.1251 - 1259. ⟨10.1002/cbic.201700024⟩ Article dans une revue hal-01741238v1
Glycosylation Changes Triggered by the Differentiation of Monocytic THP-1 Cell Line into Macrophages Clément Delannoy,Yoann Rombouts,Sophie Groux-Degroote,Stephanie Holst,Bernadette Coddevilleet al. Journal of Proteome Research, 2016, 16 (1), pp.156 - 169. ⟨10.1021/acs.jproteome.6b00161⟩ Article dans une revue hal-01931172v1
Differentiation of Crohn’s Disease-Associated Isolates from Other Pathogenic Escherichia coli by Fimbrial Adhesion under Shear Force Sabine Szunerits,Oleksandr Zagorodko,Virginie Cogez,Tetiana Dumych,Thibaut Chalopinet al. Biology, 2016, 5 (2), ⟨10.3390/biology5020014⟩ Article dans une revue hal-01741244v1
Improved workflow for the efficient preparation of ready to use CMP-activated sialic acids Pierre-André Gilormini,Cedric Lion,Maxence Noel,Marie-Ange Krzewinski-Recchi,Anne Harduin-Leperset al. Glycobiology, 2016, ⟨10.1093/glycob/cww084⟩ Article dans une revue hal-01741256v1
Host glycosylation pathways and the unfolded protein response contribute to the infection by Francisella Monique Barel,Anne Harduin-Lepers,Lucie Portier,Marie-Christine Slomianny,Alain Charbit Cellular Microbiology, 2016, 18 (12), pp.1763 - 1781. ⟨10.1111/cmi.12614⟩ Article dans une revue hal-01741247v1
Phylogenetic-Derived Insights into the Evolution of Sialylation in Eukaryotes: Comprehensive Analysis of Vertebrate β-Galactoside α2,3/6-Sialyltransferases (ST3Gal and ST6Gal). Roxana E Teppa,Daniel Petit,Olga Plechakova,Virginie Cogez,Anne Harduin-Lepers International Journal of Molecular Sciences, 2015, 17 (8), ⟨10.3390/ijms17081286⟩ Article dans une revue (article de synthèse) hal-01358174v1
Integrative View of α2,3-Sialyltransferases (ST3Gal) Molecular and Functional Evolution in Deuterostomes: Significance of Lineage-Specific Losses Daniel Petit,Elin Teppa,Anne Mir,Dorothée Vicogne,Christine Thisseet al. Molecular Biology and Evolution, 2015, 32 (4), pp.906 - 927. ⟨10.1093/molbev/msu395⟩ Article dans une revue hal-01741239v1
Sialic Acid Expression in the Mosquito Aedes aegypti and Its Possible Role in Dengue Virus-Vector Interactions. Jorge Cime-Castillo,Philippe Delannoy,Guillermo Mendoza-Hernández,Verónica Monroy-Martínez,Anne Harduin-Leperset al. BioMed Research International , 2015, 2015, pp.504187. ⟨10.1155/2015/504187⟩ Article dans une revue hal-01143777v1
B4GALNT2 gene expression controls the biosynthesis of Sd(a) and sialyl Lewis X antigens in healthy and cancer human gastrointestinal tract. Sophie Groux-Degroote,Cindy Wavelet,Marie-Ange Krzewinski-Recchi,Lucie Portier,Marlène Mortuaireet al. International Journal of Biochemistry and Cell Biology, 2014, epub ahead of print. ⟨10.1016/j.biocel.2014.06.009⟩ Article dans une revue hal-01020099v1
The α1,6-Fucosyltransferase Gene (fut8) from the Sf9 Lepidopteran Insect Cell Line: Insights into fut8 Evolution Sylvie Juliant,Anne Harduin-Lepers,François Monjaret,Béatrice Catieau,Marie-Luce Violetet al. PLoS ONE, 2014, 9 (10), pp.e110422. ⟨10.1371/journal.pone.0110422⟩ Article dans une revue hal-01224133v1
The expanding roles of the Sda/Cad carbohydrate antigen and its cognate glycosyltransferase B4GALNT2 Fabio Dall'Olio,Nadia Malagolini,Mariella Chiricolo,Marco Trinchera,Anne Harduin-Lepers Biochimica et Biophysica Acta (BBA) - General Subjects, 2014, 1840 (1), pp.443-453. ⟨10.1016/j.bbagen.2013.09.036⟩ Article dans une revue hal-02350659v1
The α1,6-Fucosyltransferase Gene (fut8) from the Sf9 Lepidopteran Insect Cell Line: Insights into fut8 Evolution Sylvie Juliant,Anne Harduin-Lepers,François Monjaret,Béatrice Catieau,Marie-Luce Violetet al. PLoS ONE, 2014, 9 (10), ⟨10.1371/journal.pone.0110422⟩ Article dans une revue hal-01741262v1
The expanding roles of the Sda/Cad carbohydrate antigen and its cognate glycosyltransferase B4GALNT2 Fabio Dall'Olio,Nadia Malagolini,Mariella Chiricolo,Marco Trinchera,Anne Harduin-Leperset al. BBA - Biochimica et Biophysica Acta, 2014, 1840 (1), pp.443-53. ⟨10.1016/j.bbagen.2013.09.036⟩ Article dans une revue hal-01081501v1
TNF induces the expression of the sialyltransferase ST3Gal IV in human bronchial mucosa via MSK1/2 protein kinases and increases FliD/sialyl-Lewisx mediated adhesion of Pseudomonas aeruginosa. Florent Colomb,Olivier Vidal,Marie Bobowski,Marie-Ange Krzewinski-Recchi,Anne Harduin-Leperset al. Biochemical Journal, 2013, 457 (1), pp.79-87. ⟨10.1042/BJ20130989⟩ Article dans une revue hal-00872219v1
The expanding roles of the Sd(a)/Cad carbohydrate antigen and its cognate glycosyltransferase B4GALNT2. Fabio Dall'Olio,Nadia Malagolini,Mariella Chiricolo,Marco Trinchera,Anne Harduin-Lepers BBA - Biochimica et Biophysica Acta, 2013, 1840 (1), pp.443-53 Article dans une revue hal-01224139v1
Sialyltransferases functions in cancers. Anne Harduin-Lepers,Marie-Ange Krzewinski-Recchi,Florent Colomb,Francois Foulquier,Sophie Groux-Degrooteet al. Front Biosci (Elite Ed), 2012, 4, pp.499-515 Article dans une revue hal-00656027v1
Mapping the expressed glycome and glycosyltransferases of zebrafish liver cells as a relevant model system for glycosylation studies. Jorick Vanbeselaere,Lan-Yi Chang,Anne Harduin-Lepers,Emeline Fabre,Nao Yamakawaet al. Journal of Proteome Research, 2012, 11 (4), pp.2164-77 Article dans une revue hal-01224143v1
Mapping the Expressed Glycome and Glycosyltransferases of Zebrafish Liver Cells as a Relevant Model System for Glycosylation Studies Jorick Vanbeselaere,Lan-Yi Chang,Anne Harduin-Lepers,Emeline Fabre,Nao Yamakawaet al. Journal of Proteome Research, 2012, 11 (4), pp.2164-2177. ⟨10.1021/pr200948j⟩ Article dans une revue hal-02350669v1
Sialome analysis of the cephalochordate Branchiostoma belcheri, a key organism for vertebrate evolution. Yann Guérardel,Lan-Yi Chang,Akiko Fujita,Bernadette Coddeville,Emmanuel Maeset al. Glycobiology, 2012, 22 (4), pp.479-91 Article dans une revue hal-01224146v1
TNF regulates sialyl-Lewis(x) and 6-sulfo-sialyl-Lewis(x) expression in human lung through up-regulation of ST3GAL4 transcript isoform BX. Florent Colomb,Marie-Ange Krzewinski-Recchi,Fala El Machhour,Eric Mensier,Sophie Jaillardet al. Biochimie, 2012, 94 (9), pp.2045-53. ⟨10.1016/j.biochi.2012.05.030⟩ Article dans une revue istex hal-00708570v1
Sialome analysis of the cephalochordate Branchiostoma belcheri, a key organism for vertebrate evolution Y. Guérardel,L.-Y. Chang,A. Fujita,B. Coddeville,E. Maeset al. Glycobiology, 2012, 22 (4), pp.479-491. ⟨10.1093/glycob/cwr155⟩ Article dans une revue hal-02350673v1
Molecular cloning, characterization, genomic organization and promoter analysis of the alpha1,6-fucosyltransferase gene (fut8) expressed in the rat hybridoma cell line YB2/0. Beatrice Teylaert,Edwige Meurice,Marie Bobowski,Anne Harduin-Lepers,Christine Gaucheret al. BMC Biotechnology, 2011, 11 (1), pp.1. ⟨10.1186/1472-6750-11-1⟩ Article dans une revue hal-00553309v1
Current trends in the structure-activity relationships of sialyltransferases. Magali Audry,Charlotte Jeanneau,Anne Imberty,Anne Harduin-Lepers,Philippe Delannoyet al. Glycobiology, 2011, 21 (6), pp.716-26. ⟨10.1093/glycob/cwq189⟩ Article dans une revue hal-01224155v1
Molecular Phylogeny and Functional Genomics of {beta}-Galactoside {alpha}2,6-Sialyltransferases That Explain Ubiquitous Expression of st6gal1 Gene in Amniotes. Daniel Petit,Anne-Marie Mir,Jean-Michel Petit,Christine Thisse,Philippe Delannoyet al. Journal of Biological Chemistry, 2010, 285 (49), pp.38399-414. ⟨10.1074/jbc.M110.163931⟩ Article dans une revue hal-00521411v1
Consequences of the expression of sialylated antigens in breast cancer. Aurélie Cazet,Sylvain Julien,Marie Bobowski,Marie-Ange Krzewinski-Recchi,Anne Harduin-Leperset al. Carbohydrate Research, 2010, 345, pp.1377-1383. ⟨10.1016/j.carres.2010.01.024⟩ Article dans une revue istex hal-00464837v1
Developmental regulation of oligosialylation in zebrafish Lan-Yi Chang,Anne Harduin-Lepers,Ken Kitajima,Chihiro Sato,C. J. Huanget al. Glycoconjugate Journal, 2009, 26 (3), pp.247-261. ⟨10.1007/s10719-008-9161-5⟩ Article dans une revue istex hal-00642030v1
Molecular cloning and characterization of the expression pattern of the zebrafish alpha2, 8-sialyltransferases (ST8Sia) in the developing nervous system. Lan-Yi Chang,Anne-Marie Mir,Christine Thisse,Yann Guérardel,Philippe Delannoyet al. Glycoconjugate Journal, 2009, 26 (3), pp.263-75. ⟨10.1007/s10719-008-9165-1⟩ Article dans une revue istex hal-00318148v1
Differential expression of alpha-2,3-sialyltransferases and alpha-1,3/4-fucosyltransferases regulates the levels of sialyl Lewis a and sialyl Lewis x in gastrointestinal carcinoma cells. A. S. Carvalho,A. Harduin-Lepers,A. Magalhães,E. Machado,N. Mendeset al. International Journal of Biochemistry and Cell Biology, 2009, epub ahead of print. ⟨10.1016/j.biocel.2009.09.010⟩ Article dans une revue istex hal-00423661v1
Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes. Anne Harduin-Lepers,Daniel Petit,Rosella Mollicone,Philippe Delannoy,Jean-Michel Petitet al. BMC Evolutionary Biology, 2008, 8 (1), pp.258. ⟨10.1186/1471-2148-8-258⟩ Article dans une revue hal-00328132v1
Protein ubiquitination is modulated by O-GlcNAc glycosylation. Céline Guinez,Anne-Marie Mir,Vanessa Dehennaut,René Cacan,Anne Harduin-Leperset al. FASEB Journal, 2008, 22 (8), pp.2901-11. ⟨10.1096/fj.07-102509⟩ Article dans une revue hal-00318447v1
Biological significance of cancer-associated sialyl-Tn antigen: modulation of malignant phenotype in gastric carcinoma cells. Sandra Pinho,Nuno T Marcos,Bibiana Ferreira,Ana S Carvalho,Maria J Oliveiraet al. Cancer Letters, 2007, 249 (2), pp.157-70. ⟨10.1016/j.canlet.2006.08.010⟩ Article dans une revue istex hal-00164921v1
Probing the substrate specificity of four different sialyltransferases using synthetic β-d-Galp-(1→4)-β-d-GlcpNAc-(1→2)-α-d-Manp-(1→O) (CH2)7CH3 analogues Philippe Rohfritsch,John A.F. Joosten,Marie-Ange Krzewinski-Recchi,Anne Harduin-Lepers,Benoît B. Laporteet al. Biochimica et Biophysica Acta (BBA) - General Subjects, 2006, 1760 (4), pp.685-692. ⟨10.1016/j.bbagen.2005.12.012⟩ Article dans une revue istex hal-02350677v1
Probing the substrate specificity of four different sialyltransferases using synthetic beta-D-Galp-(1--&gt;4)-beta-D-GlcpNAc-(1--&gt;2)-alpha-D-Manp-(1--&gt;O) (CH(2))7CH3 analogues general activating effect of replacing N-acetylglucosamine by N-propionylglucosamine. Philippe F. Rohfritsch,John A.F. Joosten,Marie-Ange Krzewinski-Recchi,Anne Harduin-Lepers,Benoit Laporteet al. BBA - Biochimica et Biophysica Acta, 2006, 1760, pp.685-92 Article dans une revue hal-00085751v1
Molecular cloning and expression of a human hST8Sia VI (α2,8-sialyltransferase) responsible for the synthesis of the diSia motif on O-glycosylproteins Mélanie Teintenier-Lelièvre,Sylvain Julien,Sylvie Juliant,Yann Guerardel,Martine Duonor-Ceruttiet al. Biochemical Journal, 2005, 392 (3), pp.665-674. ⟨10.1042/BJ20051120⟩ Article dans une revue hal-02350683v1
Erratum Anne Harduin-Lepers Glycobiology, 2005, 15 (9), pp.21G-21G. ⟨10.1093/glycob/cwj012⟩ Article dans une revue hal-02350681v1
The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach. Anne Harduin-Lepers,Rosella Mollicone,Philippe Delannoy,Rafael Oriol Glycobiology, 2005, 15, pp.805-17 Article dans une revue hal-00085761v1
The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach Anne Harduin-Lepers,Rosella Mollicone,Philippe Delannoy,Rafael Oriol Glycobiology, 2005, 15 (8), pp.805-817. ⟨10.1093/glycob/cwi063⟩ Article dans une revue hal-02350684v1
Molecular cloning and expression of a human hST8Sia VI (alpha2,8-sialyltransferase) responsible for the synthesis of the diSia motif on O-glycosylproteins. Mélanie Teintenier-Lelièvre,Sylvain Julien,Sylvie Juliant,Yann Guerardel,Martine Duonor-Ceruttiet al. Biochemical Journal, 2005, 392(Pt 3), pp.665-74 Article dans une revue hal-00085757v1
Structure-function analysis of the human sialyltransferase ST3Gal I: role of n-glycosylation and a novel conserved sialylmotif Charlotte Jeanneau,Valérie Chazalet,Claudine Augé,Dikeos Mario Soumpasis,Anne Harduin-Leperset al. Journal of Biological Chemistry, 2004, 279 (14), pp.13461-8. ⟨10.1074/jbc.M311764200⟩ Article dans une revue hal-00086299v1
Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen. Nuno T Marcos,Sandra Pinho,Catarina Grandela,Andrea Cruz,Bénédicte Samyn-Petitet al. Cancer Research, 2004, 64 (19), pp.7050-7 Article dans une revue hal-01224163v1
Role of the Human ST6GalNAc-I and ST6GalNAc-II in the Synthesis of the Cancer-Associated Sialyl-Tn Antigen Nuno Marcos,Sandra Pinho,Catarina Grandela,Andrea Cruz,Bénédicte Samyn-Petitet al. Cancer Research, 2004, 64 (19), pp.7050-7057. ⟨10.1158/0008-5472.CAN-04-1921⟩ Article dans une revue hal-02350685v1
Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain. Maria-Dolores Montiel,Marie-Ange Krzewinski-Recchi,Philippe Delannoy,Anne Harduin-Lepers Biochemical Journal, 2003, 373 (Pt 2), pp.369-79 Article dans une revue hal-01221753v1
Recombinant (2→3)-α-sialyltransferase immobilized on nickel-Agarose for preparative synthesis of sialyl Lewisx and Lewisa precursor oligosaccharides Tatiana Ivannikova,Fabrice Bintein,Annie Malleron,Sylvie Juliant,Martine Ceruttiet al. Carbohydrate Research, 2003, 338 (11), pp.1153-1161. ⟨10.1016/S0008-6215(03)00130-7⟩ Article dans une revue istex hal-02350706v1
Identification and functional expression of a second human beta-galactoside alpha2,6-sialyltransferase, ST6Gal II. Marie-Ange Krzewinski-Recchi,Sylvain Julien,Sylvie Juliant,Mélanie Teintenier-Lelièvre,Bénédicte Samyn-Petitet al. European Journal of Biochemistry, 2003, 270 (5), pp.950-61 Article dans une revue hal-01224173v1
Prognostic value of tumoral sialyltransferase expression and circulating E-selectin concentrations in node-negative breast cancer patients Mohamed Hebbar,Marie-Ange Krzewinski-Recchi,Louis Hornez,Alain Verdière,Anne Harduin-Leperset al. international Journal of Biological Markers, 2003, 18(2), pp.116-22 Article dans une revue hal-00086547v1
Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain Maria-Dolores Montiel,Marie-Ange Krzewinski-Recchi,Philippe Delannoy,Anne Harduin-Lepers Biochemical Journal, 2003, 373 (2), pp.369-379. ⟨10.1042/BJ20021892⟩ Article dans une revue hal-02350696v1
Identification and functional expression of a second human β-galactoside α2,6-sialyltransferase, ST6Gal II Marie-Ange Krzewinski-Recchi,Sylvain Julien,Sylvie Juliant,Mélanie Teintenier-Lelièvre,Bénédicte Samyn-Petitet al. European Journal of Biochemistry, 2003, 270 (5), pp.950-961. ⟨10.1046/j.1432-1033.2003.03458.x⟩ Article dans une revue hal-02350688v1
Recombinant (2--&gt;3)-alpha-sialyltransferase immobilized on nickel-agarose for preparative synthesis of sialyl Lewis(x) and Lewis(a) precursor oligosaccharides. Tatiana Ivannikova,Fabrice Bintein,Annie Malleron,Sylvie Juliant,Martine Ceruttiet al. Carbohydrate Research, 2003, 338 (11), pp.1153-61 Article dans une revue hal-01224169v1
The unfolded protein response in a dolichyl phosphate mannose-deficient Chinese hamster ovary cell line points out the key role of a demannosylation step in the quality-control mechanism of N-glycoproteins. François Foulquier,Anne Harduin-Lepers,Sandrine Duvet,Ingrid Marchal,Anne Marie Miret al. Biochemical Journal, 2002, 362 (Pt 2), pp.491-8 Article dans une revue hal-01224175v1
The unfolded protein response in a dolichyl phosphate mannose-deficient Chinese hamster ovary cell line points out the key role of a demannosylation step in the quality-control mechanism of N-glycoproteins Francois Foulquier,Anne Harduin-Lepers,Sandrine Duvet,Ingrid Marchal,Anne Marie Miret al. Biochemical Journal, 2002, 362 (2), pp.491. ⟨10.1042/0264-6021:3620491⟩ Article dans une revue hal-02350712v1
Expression of Sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc α2,6-sialyltransferase (ST6GalNAc I) cDNA Sylvain Julien,Marie-Ange Krzewinski-Recchi,Anne Harduin-Lepers,Valérie Gouyer,Guillemette Huetet al. Glycoconjugate Journal, 2001, 18 (11/12), pp.883-893. ⟨10.1023/A:1022200525695⟩ Article dans une revue istex hal-02350717v1
Expression of sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase (ST6GalNac I) cDNA. S Julien,M A Krzewinski-Recchi,Anne Harduin-Lepers,V Gouyer,G Huetet al. Glycoconjugate Journal, 2001, 18 (11-12), pp.883-93 Article dans une revue hal-01224180v1
Delineation of the minimal catalytic domain of human Galβ1-3GalNAc α2,3-sialyltransferase (hST3Gal I) Veronica Vallejo-Ruiz,Rezaul Haque,Anne-Marie Mir,Tilo Schwientek,Ulla Mandelet al. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2001, 1549 (2), pp.161-173. ⟨10.1016/S0167-4838(01)00257-6⟩ Article dans une revue istex hal-02350714v1
The human sialyltransferase family Anne Harduin-Lepers,Veronica Vallejo-Ruiz,Marie-Ange Krzewinski-Recchi,Bénédicte Samyn-Petit,Sylvain Julienet al. Biochimie, 2001, 83 (8), pp.727-737. ⟨10.1016/S0300-9084(01)01301-3⟩ Article dans une revue istex hal-02350719v1
Expression of glypican-1, syndecan-1 and syndecan-4 mRNAs protein kinase C-regulated in rat immature Sertoli cells by semi-quantitative RT-PCR analysis Anne Harduin-Lepers,S Brucato Biochimica et Biophysica Acta (BBA) - General Subjects, 2000, 1474 (1), pp.31-40. ⟨10.1016/S0304-4165(00)00006-4⟩ Article dans une revue istex hal-02350729v1
Regulation of Sialyltransferase Expression by Estradiol and 4-OH-Tamoxifen in the Human Breast Cancer Cell MCF-7 Jean-Philippe Peyrat,Marie-Ange Recchi,Mohamed Hebbar,Valérie Pawlowski,Louis Hornezet al. Molecular Cell Biology Research Communications, 2000, 3 (1), pp.48-52. ⟨10.1006/mcbr.2000.0185⟩ Article dans une revue istex hal-02350732v1
Molecular cloning and functional expression of human ST6GalNAc II. Molecular expression in various human cultured cells Bénédicte Samyn-Petit,Marie-Ange Krzewinski-Recchi,Wim F.A Steelant,Philippe Delannoy,Anne Harduin-Lepers Biochimica et Biophysica Acta (BBA) - General Subjects, 2000, 1474 (2), pp.201-211. ⟨10.1016/S0304-4165(00)00020-9⟩ Article dans une revue istex hal-02350731v1
Cloning, expression and gene organization of a human Neu5Acα2‒3Galβ1‒3GalNAc α2,6-sialyltransferase: hST6GalNAc IV Anne Harduin-Lepers,David Stokes,Wim F. a. Steelant,Bénédicte Samyn-Petit,Marie-Ange Krzewinski-Recchiet al. Biochemical Journal, 2000, 352 (1), pp.37. ⟨10.1042/0264-6021:3520037⟩ Article dans une revue hal-02350726v1
Molecular cloning, expression and exon/intron organization of the bovine ß-galactoside α2,6-sialyltransferase gene Dominique Mercier,A. Wierinckx,A. Oulmouden,P. Gallet,M. Palcicet al. Glycobiology, 1999, 9 (9), pp.851-863. ⟨10.1093/glycob/9.9.851⟩ Article dans une revue hal-02888173v1
Molecular cloning, expression and exon/intron organization of the bovine beta-galactoside alpha-2,6-sialyltransferase gene. D. Mercier,A. Wierinckx,Ahmad Oulmouden,Paul-François Gallet,M.M. Palcicet al. Glycobiology, 1999, 9, pp.851-863 Article dans une revue hal-01211835v1
Multiplex RT-PCR method for the analysis of the expression of human sialyltransferases: application to breast cancer cells Marie-Ange Recchi,Anne Harduin-Lepers,Yolande Boilly-Marer,André Verbert,Philippe Delannoy Glycoconjugate Journal, 1998, 15 (1), pp.19-27. ⟨10.1023/A:1006983214918⟩ Article dans une revue istex hal-02350739v1
Identification of two novel conserved amino acid residues in eukaryotic sialyltransferases: implications for their mechanism of action R. Geremia,A. Harduin-Lepers,P. Delannoy Glycobiology, 1997, pp.v-xi Article dans une revue hal-00309885v1
Microheterogeneity of the oligosaccharides carried by the recombinant bovine lactoferrin expressed in Mamestra brassicae cells Michel Lopez,Bernadette Coddeville,James I. Langridge,Yves Plancke,Pierre Sautièreet al. Glycobiology, 1997, 7 (5), pp.635-651. ⟨10.1093/glycob/7.5.635⟩ Article dans une revue hal-02350742v1
1994, the year of sialyltransferases Anne Harduin-Lepers,Marie-Ange Recchi,Philippe Delannoy Glycobiology, 1995, 5 (8), pp.741-758. ⟨10.1093/glycob/5.8.741⟩ Article dans une revue istex hal-02350743v1
Murine β1,4-galactosyltransferase: round spermatid transcripts are characterized by an extended 5′-untranslated region Anne Harduin-Lepers,Nancy Shaper,James Mohaney,Joel Shaper Glycobiology, 1992, 2 (4), pp.361-368. ⟨10.1093/glycob/2.4.361⟩ Article dans une revue istex hal-02350744v1
A study on the regulation of N-glycoloylneuraminic acid biosynthesis and utilization in rat and mouse liver Anne Harduin-Lepers,Anne Lepers,Lee Shaw,Petra Schneckenburger,René Cacanet al. European Journal of Biochemistry, 1990, 193 (3), pp.715-723. ⟨10.1111/j.1432-1033.1990.tb19391.x⟩ Article dans une revue hal-02350746v1
Permeabilized cells as a way of gaining access to intracellular organelles: an approach to glycosylation reactions Anne Harduin-Lepers,A. Lepers,R. Cacan,A. Verbert Biochimie, 1990, 72 (1), pp.1-5. ⟨10.1016/0300-9084(90)90166-E⟩ Article dans une revue istex hal-02350748v1
Catabolic pathway of oligosaccharide-diphospho-dolichol. Subcellular sites of the degradation of the oligomannoside moiety Anne Harduin-Lepers,René Cacan,Anne Lepers,Michel Belard,André Verbert European Journal of Biochemistry, 1989, 185 (1), pp.173-179. ⟨10.1111/j.1432-1033.1989.tb15099.x⟩ Article dans une revue hal-02350751v1
Transport of CMP- N -glycoloylneuraminic acid into mouse liver Golgi vesicles Anne Harduin-Lepers,Anne Lepers,Lee Shaw,René Cacan,Roland Schaueret al. FEBS Letters, 1989, 250 (2), pp.245-250. ⟨10.1016/0014-5793(89)80731-8⟩ Article dans une revue hal-02350752v1

Poster de conférence (1)

USING POLYSIALYLATED BIOCONJUGATES FOR IMMUNOLOGICAL APPLICATIONS Anna Steinmetz,Franziska M Kubelt,Juliane Günther,Anne Harduin-Lepers,Sebastian Peter Galuska 16th Jenner Glycobiology & Medicine Symposium, Jun 2025, Maynooth (IRL), Ireland Poster de conférence hal-05404091v1

Pré-publication, Document de travail (1)

Unliganded and CMP-Neu5Ac bound structures of human α-2,6-sialyltransferase ST6Gal I at high resolution Deborah Harrus,Anne Harduin-Lepers,Tuomo Glumoff 2020 Pré-publication, Document de travail hal-02889403v1

Chapitre d'ouvrage (7)

ST8 Alpha-N-Acetyl-Neuraminide Alpha-2,8-Sialyltransferase 1 (ST8SIA1) Marie Bobowski,Anne Harduin-Lepers,Philippe Delannoy Handbook of Glycosyltransferases and Related Genes, Springer Japan, pp.767-780, 2014, ⟨10.1007/978-4-431-54240-7_118⟩ Chapitre d'ouvrage hal-02350656v1
Vertebrate sialyltransferases Anne Harduin-Lepers Sialobiology: Structure, Biosynthesis and Function. Sialic acid glycoconjugates in health and diseases, Bentham Science Publishers, pp.85-116, 2013, 978-1-60805-067-3. ⟨10.2174/97816080538651130101⟩ Chapitre d'ouvrage hal-01224153v1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (ST8SIA1) Philippe Delannoy,Marie Bobowski,Anne Harduin-Lepers Naoyuki Taniguchi, Koichi Honke, Minoru Fukuda, Hisashi Narimatsu, Yoshiki Yamaguchi, Takashi Angata. Handbook of Glycosyltransferases and Related Genes, Springer-Verlag Berlin Heidelberg, pp.1-11, 2013, ⟨10.1007/SpringerReference_332175⟩ Chapitre d'ouvrage hal-00944778v1
Engineering the Baculovirus Genome to Produce Galactosylated Antibodies in Lepidopteran Cells Sylvie Juliant,Marylêne Lévêque,Pierre Cérutti,Annick Ozil,Sylvie Chobletet al. Sialobiology: Structure, Biosynthesis and Function. Sialic Acid Glycoconjugates in Health and Disease, BENTHAM SCIENCE PUBLISHERS, pp.59-77, 2013, ⟨10.1007/978-1-62703-327-5_5⟩ Chapitre d'ouvrage hal-02350666v1
A practical approach to reconstruct evolutionary history of animal sialyltransferases and gain insights into the sequence–function relationships of golgi-glycosyltransferases Daniel Petit,Roxana Elin Teppa,Jean-Michel Petit,Anne Harduin Glycosyltransferase, 1022, Humana Press, 2013, Methods in Molecular Biology, 978-1-62703-464-7. ⟨10.1007/978-1-62703-465-4_7⟩ Chapitre d'ouvrage hal-01211975v1
Vertebrate Sialyltransferases Anne Harduin-Lepers Sialobiology: Structure, Biosynthesis and Function. Sialic Acid Glycoconjugates in Health and Disease, BENTHAM SCIENCE PUBLISHERS, pp.139-187, 2013, ⟨10.2174/9781608053865113010008⟩ Chapitre d'ouvrage hal-02350668v1
Engineering the baculovirus genome to produce galactosylated antibodies in lepidopteran cells. Sylvie Juliant,Marylêne Lévêque,Pierre Cérutti,Annick Ozil,Sylvie Chobletet al. Methods in Molecular Biology, 988, pp.59-77, 2012 Chapitre d'ouvrage hal-01224141v1