Anthony LEMARIE

Publications

Article dans une revue (29)

Early metabolic reprogramming and carbonic anhydrase IX-mediated extracellular acidification drive radiotherapy-induced glioblastoma cell dedifferentiation Perrine Dahan,Tom Maillet,Laure Malric,Caroline Delmas,Vincent Lubranoet al. Acta Neuropathologica Communications, 2025, 14 (1), pp.1. ⟨10.1186/s40478-025-02161-2⟩ Article dans une revue hal-05519377v1
Triggering tumorigenic signaling: Succinate dehydrogenase inhibitor (SDHi) fungicides induce oncometabolite accumulation and metabolic shift in human colon cells Carolina Duarte Hospital,Arnaud Tête,Kloé Debizet,Clémence Rives,Jules Imleret al. Environment International, 2025, 199, pp.109503. ⟨10.1016/j.envint.2025.109503⟩ Article dans une revue hal-05098483v1
Fluopyram SDHI pesticide alters fish physiology and behaviour despite low in vitro effects on mitochondria Lucie Bouly,Lisa Jacquin,Florian Chapeau,Jean-Marc Bonmatin,Myriam Cousseauet al. Ecotoxicology and Environmental Safety, 2024, 288, pp.117400. ⟨10.1016/j.ecoenv.2024.117400⟩ Article dans une revue hal-04815837v1
Cytidine deaminase-dependent mitochondrial biogenesis as a potential vulnerability in pancreatic cancer cells Audrey Frances,Audrey Lumeau,Nicolas Bery,Marion Gayral,Lucille Stuaniet al. Communications Biology, 2024, 7 (1), pp.1065. ⟨10.1038/s42003-024-06760-y⟩ Article dans une revue hal-04819674v1
The STEMRI trial: Magnetic resonance spectroscopy imaging can define tumor areas enriched in glioblastoma stem-like cells Anthony Lemarié,Vincent Lubrano,Caroline Delmas,Amélie Lusque,Juan-Pablo Cerapioet al. Science Advances , 2023, 9 (44), pp.eadi0114. ⟨10.1126/sciadv.adi0114⟩ Article dans une revue hal-04299950v1
Glioblastoma Stem-like Cell Detection Using Perfusion and Diffusion MRI Tanguy Duval,Jean-Albert Lotterie,Anthony Lemarie,Caroline Delmas,Fatima Tensaoutiet al. Cancers, 2022, 14 (11), pp.2803. ⟨10.3390/cancers14112803⟩ Article dans une revue hal-04737422v1
Ionizing radiation induces endothelial transdifferentiation of glioblastoma stem-like cells through the Tie2 signaling pathway Pauline Deshors,Christine Toulas,Florent Arnauduc,Laure Malric,Aurore Siegfriedet al. Cell Death and Disease, 2019, 10 (11), pp.816. ⟨10.1038/s41419-019-2055-6⟩ Article dans une revue hal-04920735v1
Ionizing radiation induces endothelial transdifferentiation of glioblastoma stem-like cells through the Tie2 signaling pathway Pauline Deshors,Christine Toulas,Florent Arnauduc,Laure Malric,Aurore Siegfriedet al. Cell Death and Disease, 2019, 10 (11), pp.816. ⟨10.1038/s41419-019-2055-6⟩ Article dans une revue hal-04823209v1
Inhibiting integrin β8 to differentiate and radiosensitize Glioblastoma-initiating cells Laure Malric,Sylvie Monferran,Caroline Delmas,Florent Arnauduc,Perrine Dahanet al. Molecular Cancer Research, 2019, 17 (2), pp.384-397. ⟨10.1158/1541-7786.MCR-18-0386⟩ Article dans une revue hal-04823190v1
The RND1 Small GTPase: Main Functions and Emerging Role in Oncogenesis Laetitia Mouly,Julia Gilhodes,Anthony Lemarié,Elizabeth Cohen-Jonathan Moyal,Christine Toulaset al. International Journal of Molecular Sciences, 2019, 20 (15), pp.3612. ⟨10.3390/ijms20153612⟩ Article dans une revue hal-04846733v1
RND1 regulates migration of human glioblastoma stem-like cells according to their anatomical localization and defines a prognostic signature in glioblastoma Sabrina Boyrie,Caroline Delmas,Anthony Lemarié,Vincent Lubrano,Perrine Dahanet al. Oncotarget, 2018, 9 (73), pp.33788-33803. ⟨10.18632/oncotarget.26082⟩ Article dans une revue hal-01993697v1
Alpha-6 integrin promotes radioresistance of glioblastoma by modulating DNA damage response and the transcription factor Zeb1 Aline Kowalski-Chauvel,Anouchka Modesto,Laurent Baricault,Julia Gilhodes,Elizabeth Cohen-Jonathan-Moyalet al. Cell Death and Disease, 2018, 9, ⟨10.1038/s41419-018-0853-x⟩ Article dans une revue hal-04843821v1
FGFR1/FOXM1 pathway: a key regulator of glioblastoma stem cells radioresistance and a prognosis biomarker Valérie Gouazé-Andersson,Marie-Julie Ghérardi,Anthony Lemarié,Julia Gilhodes,Vincent Lubranoet al. Oncotarget, 2018, 9 (60), pp.31637-31649. ⟨10.18632/oncotarget.25827⟩ Article dans une revue hal-04846463v1
Interest of integrins targeting in glioblastoma according to tumor heterogeneity and cancer stem cell paradigm: an update Laure Malric,Sylvie Monferran,Julia Gilhodes,Sabrina Boyrie,Perrine Dahanet al. Oncotarget, 2017, 8 (49), pp.86947-86968. ⟨10.18632/oncotarget.20372⟩ Article dans une revue hal-04866555v1
The environmental carcinogen benzo[a]pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival Kevin Hardonnière,Elise Saunier,Anthony Lemarié,Morgane Fernier,Isabelle Gallaiset al. Scientific Reports, 2016, 6 (1), pp.30776. ⟨10.1038/srep30776⟩ Article dans une revue hal-01359569v1
Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response Julie Sesen,Perrine Dahan,Sarah Scotland,Estelle Saland,Van-Thi Danget al. PLoS ONE, 2015, 10 (4), pp.e0123721. ⟨10.1371/journal.pone.0123721⟩ Article dans une revue hal-04851709v1
Stefan Grimm, 1963-2014, a tragic loss for the scientific community Obituary A-L Mahul-Mellier,Laurence Huc,A. Lemarié,S. Irshad,M. Hwanget al. Cell Death and Differentiation, 2015, 22 (2), pp.247. ⟨10.1038/cdd.2014.196⟩ Article dans une revue hal-02629476v1
Int6/eIF3e Is Essential for Proliferation and Survival of Human Glioblastoma Cells. Julie Sesen,Anne Cammas,Sarah J. Scotland,Bertand Elefterion,Anthony Lemariéet al. International Journal of Molecular Sciences, 2014, 15 (2), pp.2172-90. ⟨10.3390/ijms15022172⟩ Article dans une revue inserm-00941168v1
RhoB Promotes γH2AX Dephosphorylation and DNA Double-Strand Break Repair Kenza Mamouni,Agnese Cristini,Josee Guirouilh-Barbat,Sylvie Monferran,Anthony Lemariéet al. Molecular and Cellular Biology, 2014, 34 (16), pp.3144-3155. ⟨10.1128/MCB.01525-13⟩ Article dans une revue hal-03048228v1
Ionizing radiations sustain glioblastoma cell dedifferentiation to a stem-like phenotype through survivin: possible involvement in radioresistance P Dahan,J Martinez Gala,C Delmas,Sylvie Monferran,L Malricet al. Cell Death and Disease, 2014, 5 (11), pp.e1543. ⟨10.1038/cddis.2014.509⟩ Article dans une revue hal-04851727v1
Low concentrations of bisphenol A induce lipid accumulation mediated by the production of reactive oxygen species in the mitochondria of HepG2 cells Laurence Huc,Anthony Lemarié,Françoise Guéraud,Cécile Héliès-Toussaint Toxicology in Vitro, 2012, 26 (5), pp.709-717. ⟨10.1016/j.tiv.2012.03.017⟩ Article dans une revue istex hal-02940780v1
Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer? A Lemarie,S Grimm Oncogene, 2011, 30 (38), pp.3985-4003. ⟨10.1038/onc.2011.167⟩ Article dans une revue hal-04866571v1
Specific disintegration of complex II succinate:ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction Stefan Grimm,Anthony Lemarie,Laurence Huc,Evangelos Pazarentzos,Anne-Laure Mahul-Mellier Cell Death and Differentiation, 2010, 18 (2), pp.338-349. ⟨10.1038/cdd.2010.93⟩ Article dans une revue hal-00565452v1
Mutations in the heme b-binding residue of SDHC inhibit assembly of respiratory chain complex II in mammalian cells Anthony Lemarie,Stefan Grimm Mitochondrion, 2009, 9 (4), pp.254-260. ⟨10.1016/j.mito.2009.03.004⟩ Article dans une revue istex hal-04852069v1
Isolation of ORCTL3 in a novel genetic screen for tumor-specific apoptosis inducers S Irshad,A-L Mahul-Mellier,N Kassouf,A Lemarie,S Grimm Cell Death and Differentiation, 2009, 16 (6), pp.890-898. ⟨10.1038/cdd.2009.21⟩ Article dans une revue hal-04852056v1
Inorganic arsenic activates reduced NADPH oxidase in human primary macrophages through a Rho kinase/p38 kinase pathway. Anthony Lemarie,Emilie Bourdonnay,Claudie Morzadec,Olivier Fardel,Laurent Vernhet Journal of Immunology, 2008, 180 (9), pp.6010-7 Article dans une revue hal-00673108v1
Human macrophages constitute targets for immunotoxic inorganic arsenic. Anthony Lemarie,Claudie Morzadec,Emilie Bourdonnay,Olivier Fardel,Laurent Vernhet Journal of Immunology, 2006, 177 (5), pp.3019-27. ⟨10.4049/jimmunol.177.5.3019⟩ Article dans une revue hal-00699559v1
Arsenic trioxide induces apoptosis of human monocytes during macrophagic differentiation through nuclear factor-kappaB-related survival pathway down-regulation. Anthony Lemarie,Claudie Morzadec,Delphine Mérino,Olivier Micheau,Olivier Fardelet al. Journal of Pharmacology and Experimental Therapeutics, 2006, 316 (1), pp.304-14. ⟨10.1124/jpet.105.092874⟩ Article dans une revue hal-00699564v1
Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor Anthony Lemarié,Dominique Lagadic-Gossmann,Claudie Morzadec,Nathalie Allain,Olivier Fardelet al. Free Radical Biology and Medicine, 2004, 36 (12), pp.1517-1531. ⟨10.1016/j.freeradbiomed.2004.03.020⟩ Article dans une revue istex hal-04866201v1

Proceedings/Recueil des communications (8)

Glioblastoma Stem-like Cell Detection using Advanced MR Imaging: results from the STEMRI trial Vincent Lubrano,Tanguy Duval,Anthony Lemarié,Caroline Delmas,Thomas Filleronet al. EANS (European Association of Neurosurgical Societies) 2024, Brain and Spine, 4, pp.103489, 2024, ⟨10.1016/j.bas.2024.103489⟩ Proceedings/Recueil des communications hal-04852271v1
Glioblastoma heterogeneity and cancer stem-like cells detection with advanced MRI in the non contrast enhancing tumor: time to personalized surgery and therapeutic paradigm shift? T. Duval,J.-A. Lotterie,A. Lemarie,C. Delmas,R. Howellset al. eEANS (European Association of Neurosurgical Societies) 2021, Brain and Spine, 1, pp.100512, 2021, ⟨10.1016/j.bas.2021.100512⟩ Proceedings/Recueil des communications hal-04852285v1
Ionizing radiation induces endothelial transdifferentiation of glioblastoma stem-like cells through the Tie2 signaling pathway Solène Evrard,Pauline Deshors,Christine Toulas,Florent Arnauduc,Laure Malricet al. AM/CHEC 2021, Morphologie, 105 (350), pp.S20, 2021, ⟨10.1016/j.morpho.2021.05.039⟩ Proceedings/Recueil des communications hal-04852304v1
Abstract A23: Characterization of novel molecular vulnerabilities provoking replicative and energetic stresses in pancreatic cancer cells Marion Gayral,Audrey Frances,Estelle Saland,Hubert Lulka,Naima Hanounet al. AACR Special Conference on Pancreatic Cancer: Advances in Science and Clinical Care 2016, Cancer Research, 76 (24_Supplement), pp.A23-A23, 2016, ⟨10.1158/1538-7445.PANCA16-A23⟩ Proceedings/Recueil des communications hal-04852328v1
Lessons learned from first-in-man gene therapy clinical trial for pancreatic cancer: targeting tumor metabolism to tackle chemoresistance M Gayral,E Saland,H Lulka,A Vignolle-Vidoni,N. Hanounet al. ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015, Human Gene Therapy, 26 (10), pp.A-1-A-108 OR002, 2015, ⟨10.1089/hum.2015.29008.abstracts⟩ Proceedings/Recueil des communications hal-04865824v1
PO-1078 Ionizing radiations sustain Glioblastoma cell dedifferentiation to a stem phenotype through Survivin P. Dahan,J. Martinez Gala,C. Delmas,S. Monferran,L. Malricet al. 3rd ESTRO Forum 2015, Radiotherapy & Oncology, 115, pp.S582, 2015, ⟨10.1016/S0167-8140(15)41070-9⟩ Proceedings/Recueil des communications hal-04865842v1
PO-43: Long-Term Effects of Irradiation on The Phenotype of Human Glioblastoma Cells A. Lemarie,J. Martinez Gala,P. Dahan,C. Delmas,S. Monferranet al. 4th Symposium on Novel Targeting Drugs & Radiotherapy "From the bench to the clinic", Radiotherapy & Oncology, 104, pp.34-35, 2012, ⟨10.1016/S0167-8140(15)34597-7⟩ Proceedings/Recueil des communications istex hal-04865856v1
Le trioxyde d'arsenic induit l'apoptose des monocytes humains en culture primaire lors de la différenciation macrophagique: implication du facteur nucléaire de transcription NF-kappaB Anthony Lemarié,Claudie Morzadec,Olivier Fardel,Laurent Vernhet 14ème Forum de Cancérologie - Eurocancer, Bulletin du Cancer, 91 (544), 2004 Proceedings/Recueil des communications hal-04873203v1

Poster de conférence (9)

The STEMRI trial: magnetic resonance spectroscopy imaging can define tumor areas enriched in glioblastoma-initiating cells A Lemarié,V Lubrano,C Delmas,A Lusque,Jp Cerapioet al. 5th SUNRISE Meeting: Stem Cells & Cancer, May 2024, Ajaccio, France Poster de conférence hal-04992301v1
Interrelations between tumor metabolic heterogeneity and Glioblastoma stem cells metabolic response to irradiation : impact on radioresistance T Maillet,A Hagimont,C Delmas,Y Nicaise,P Dahanet al. 5th Metabolism & Cancer international Congress, Nov 2023, Nice, France Poster de conférence hal-04992298v1
Early metabolic reprogramming drives Glioblastoma cell dedifferentiation to a stem phenotype in response to ionizing radiations P Dahan,L Malric,C Delmas,T Maillet,V Lubranoet al. 4th SUNRISE Meeting: Stem Cells & Cancer, Jun 2022, Paris, France Poster de conférence hal-04992296v1
Effect of irradiation on transdifferentiation of GSC Radio-induced transdifferentiation of Glioblastoma Stem Cells into Endothelial Cells P Deshors,L Malric,F Arnauduc,A Lemarié,E Cohen-Jonathan-Moyalet al. 25ème journées du CHEC, Mar 2021, En ligne, France Poster de conférence hal-04940439v1
Implication of FGFR1/FOXM1 pathway in the regulation of glioblastoma stem cells radioresistance and as a prognosis biomarker. Valérie Gouazé-Andersson,Marie-Julie Ghérardi,Anthony Lemarié,Julia Gilhodes,Vincent Lubranoet al. 3rd SUNRISE Meeting - New advanced in cancer stem cells, May 2019, Nice, France Poster de conférence hal-04846276v1
Combined diffusion and perfusion MRI in Glioblastoma predicts glial stem cells proliferation and aggressiveness T Duval,Ja Lotterie,A Lemarie,C Delmas,C Toulaset al. 27th ISMRM meeting, May 2019, MONTREAL, Canada Poster de conférence hal-04992290v1
RND1 regulates migration of human glioblastoma stem-like cells according to their anatomical localization and defines a prognostic signature in glioblastoma S Boyrie,C Delmas,V Lubrano,P Dahan,L Malricet al. 3d SUNRISE Meeting: Stem Cells & Cancer, Jun 2019, Nice, France Poster de conférence hal-04992294v1
Role of β8 integrin in stemness maintenance and radioresistance of glioblastoma-initiating cells L Malric,S Monferran,C Delmas,F Arnauduc,P Dahanet al. 3d SUNRISE Meeting: Stem Cells & Cancer, Jun 2019, Nice, France Poster de conférence hal-04992292v1
Complex II specific dissociation links pH changes to oxidative stress for apoptosis induction Anthony Lemarié,Laurence Huc,Evangelos Pazarentzos,Anne-Laure Mahul-Mellier,Stefan Grimm Abcam 2010 - Cancer and Metabolism: Pathways to the Future meeting, Sep 2010, Edinbourg, Ecosse, United Kingdom. F1000Posters, 1 (551), 2010 Poster de conférence hal-04866023v1

Communication dans un congrès (3)

Interrelations between tumor metabolic heterogeneity and Glioblastoma stem cells metabolic response to irradiation : impact on radioresistance T Maillet,A Hagimont,C Delmas,Y Nicaise,P Dahanet al. 5th SUNRISE Meeting: Stem Cells & Cancer, May 2024, Ajaccio, France Communication dans un congrès hal-04992310v1
Complex II specific dissociation links pH changes to oxidative stress for apoptosis induction A Lemarie,Laurence Huc,E Pazarentzos,Anne-Laure Mahul-Mellier,S Grimm 1st international congress Cell Death In Cancer (CDIC), May 2012, St-Malo, France Communication dans un congrès hal-02744416v1
Complex II specific dissociation links pH changes to oxidative stress for apoptosis induction A. Lemarié,Laurence Huc,. Pazarentzos E, Mahul-Mellier Al And Grimm S. . 2nd Symposium of the International Society for Proton Dynamics in Cancer (ISPDC) Basic Research to Cancer Treatment, Saisissez le nom du laboratoire, du service ou du département., Ville service., Nov 2011, Nice, France Communication dans un congrès hal-02804053v1

Rapport (2)

Rapport d'expertise collective ANSES : Actualisation des données relatives aux substances phytopharmaceutiques de la famille des inhibiteurs de la succinate déshydrogénase (SDHI) Claude Emond,Thierry Baron,Sylvie Bortoli,Frédéric Bouillaud,Thomas Claudepierreet al. ANSES. 2023 Rapport hal-04873181v1
OPINION of the French Agency for Food, Environmental and Occupational Health & Safety on &quot;Updating data on succinate dehydrogenase inhibitor (SDHI)-based plant protection substances Claude Emond,Thierry Baron,Sylvie Bortoli,Frédéric Bouillaud,Thomas Claudepierreet al. Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES). 2023, 50 p Rapport (rapport d’expertise collective) anses-05468521v1

HDR (1)

Mourir ou s’adapter : comment les cellules humaines répondent aux agents chimio et radio-thérapeutiques en fonction de l’hétérogénéité cellulaire et tumorale Anthony Lemarié Cancer. Université toulouse 3 Paul Sabatier, 2023 HDR tel-04873346v1

Brevet (2)

New compound, preferably antagonist of beta-8 integrin or inhibitor of expression of beta-8 integrin used for treating resistant glioblastoma A Lemarie,L Malric,C Toulas,E Cohen Jonathan Moyal France, Patent n° : WO2017182834A1. 2016 Brevet hal-04992318v1
New compound, preferably antagonist of beta-8 integrin or inhibitor of expression of beta-8 integrin used for treating resistant glioblastoma A Lemarie,L Malric,C Toulas,E Cohen Jonathan Moyal France, Patent n° : EP3009147-A1. 2014 Brevet hal-04992314v1