Antoine Rimbert

Identifiants chercheurs

IdHAL :

antoine-rimbert

ORCID :

0000-0002-2971-4926

IdRef :

193066904

Publications

Article dans une revue (45)

Versatile Functions of Hepatic Lipase in Lipoprotein Metabolism Wieneke Dijk,Antoine Rimbert,Thibaud Sotin,Cedric Le May,Bertrand Cariou Arteriosclerosis, Thrombosis, and Vascular Biology, 2026, 46 (1), pp.105-118. ⟨10.1161/ATVBAHA.125.323051⟩ Article dans une revue hal-05500165v1
Synergic combination of the monogenic ANGPTL3 p.H343R variant and a polygenic predisposition in a family with hypobetalipoproteinemia Manon Levy,Alexandre Janin,Oriane Marmontel,Anthony Fourier,Séverine Nonyet al. Atherosclerosis, 2025, 411, pp.120569. ⟨10.1016/j.atherosclerosis.2025.120569⟩ Article dans une revue hal-05361341v1
Loss of GPR146 decreases plasma levels of HDL cholesterol via post-translational up-regulation of SR-B1 protein levels Boyan Zhang,Natalia Loaiza,Antoine Rimbert,Federico Oldoni,Lisanne Blauwet al. Cardiovascular Research, 2025, ⟨10.1093/cvr/cvaf254⟩ Article dans une revue hal-05489608v1
KILDA: identifying KIV-2 repeats from kmers Corentin Molitor,Timothy Labidi,Antoine Rimbert,Bertrand Cariou,Mathilde Di Filippoet al. NAR Genomics and Bioinformatics, 2025, 7 (2), pp.lqaf070. ⟨10.1093/nargab/lqaf070⟩ Article dans une revue hal-05361347v1
A study into rare GPR146 gene variants in humans and mice Boyan Zhang,Antoine Rimbert,Antoine Lainé,Nicolette Huijkman,Niels Kloosterhuiset al. Atherosclerosis, 2025, 403, ⟨10.1016/j.atherosclerosis.2025.119137⟩ Article dans une revue hal-05361359v1
Casz1 and Znf101/Zfp961 differentially regulate apolipoproteins A1 and B, alter plasma lipoproteins, and reduce atherosclerosis Abulaish Ansari,Pradeep Kumar Yadav,Liye Zhou,Binu Prakash,Laraib Ijazet al. JCI Insight, 2025, 10 (1), pp.e182260. ⟨10.1172/jci.insight.182260.⟩ Article dans une revue hal-05361367v1
From Genetic Findings to new Intestinal Molecular Targets in Lipid Metabolism Cedric Le May,Simon Ducheix,Bertrand Cariou,Antoine Rimbert Current Atherosclerosis Reports, 2025, 27 (1), pp.26. ⟨10.1007/s11883-024-01264-w⟩ Article dans une revue hal-05361443v1
DHCR24 inhibitor SH42 increases desmosterol without preventing atherosclerosis development in mice Xiaoke Ge,Bram Slütter,Joost Lambooij,Enchen Zhou,Zhixiong Yinget al. iScience, 2024, 27 (6), pp.109830. ⟨10.1016/j.isci.2024.109830⟩ Article dans une revue hal-04751124v1
MicroRNA-615-3p decreases apo B expression in human liver cells Abulaish Ansari,Pradeep Kumar Yadav,Swati Valmiki,Antoine Laine,Antoine Rimbertet al. Journal of Lipid Research, 2024, 65 (10), pp.100659. ⟨10.1016/j.jlr.2024.100659⟩ Article dans une revue hal-04751117v1
Primary hypocholesterolemia is associated with an increased risk of hepatic complications in the general population Matthieu Wargny,Thomas Goronflot,Antoine Rimbert,Jérôme Boursier,Sofiane Kabet al. Journal of Hepatology, 2024, 80 (6), pp.846-857. ⟨10.1016/j.jhep.2024.01.030⟩ Article dans une revue hal-04474613v2
Human induced pluripotent stem cells ‐derived liver organoids grown on a Biomimesys® hyaluronic acid‐based hydroscaffold as a new model for studying human lipoprotein metabolism Meryl Roudaut,Amandine Caillaud,Zied Souguir,Lise Bray,Aurore Girardeauet al. Bioengineering & Translational Medicine, 2024, ⟨10.1002/btm2.10659⟩ Article dans une revue (data paper) hal-04509118v1
PCSK9 inhibition protects mice from food allergy Victoria Lorant,Martin Klein,Damien Garçon,Thibaud Sotin,Samuel Freyet al. Translational Research, The Journal of Laboratory and Clinical Medicine, 2024, 272, pp.151-161. ⟨10.1016/j.trsl.2024.03.001⟩ Article dans une revue hal-04529957v1
G protein-coupled receptor 146: new insights from genetics and model systems Umesh Tharehalli,Antoine Rimbert Current Opinion in Lipidology, 2024, 35 (3), pp.162-169. ⟨10.1097/MOL.0000000000000929⟩ Article dans une revue hal-04529967v2
Reply to “The association between primary hypobetalipoproteinemia and hepatic diseases: evidence from genetic studies” Antoine Rimbert,Matthieu Wargny,Bertrand Cariou Journal of Hepatology, 2024, 82 (1), pp.e50 - e51. ⟨10.1016/j.jhep.2024.09.009⟩ Article dans une revue hal-05361515v2
Advancements in risk stratification and management strategies in primary cardiovascular prevention Fotios Barkas,Yusuf Ziya Sener,Pelin Arabacilar Golforoush,Azin Kheirkhah,Elena Rodriguez-Sanchezet al. Atherosclerosis, 2024, 395, pp.117579. ⟨10.1016/j.atherosclerosis.2024.117579⟩ Article dans une revue hal-04751122v1
LDL lowering effect of PCSK9 inhibition is reduced in women Veronika Myasoedova,Antoine Rimbert,Marina Camera,Cedric Le May,Romain Capouladeet al. European Heart Journal - Cardiovascular Pharmacotherapy, 2023, 9 (4), pp.337-342. ⟨10.1093/ehjcvp/pvad009⟩ Article dans une revue hal-04212334v1
A new 165-SNP low-density lipoprotein cholesterol polygenic risk score based on next generation sequencing outperforms previously published scores in routine diagnostics of familial hypercholesterolemia Xavier Vanhoye,Claire Bardel,Antoine Rimbert,Philippe Moulin,Pierre-Antoine Rollat-Farnieret al. Translational Research, The Journal of Laboratory and Clinical Medicine, 2023, 255, pp.119-127. ⟨10.1016/j.trsl.2022.12.002⟩ Article dans une revue hal-04172500v1
Hepatic SREBP signaling requires SPRING to govern systemic lipid metabolism in mice and humans Sebastian Hendrix,Jenina Kingma,Roelof Ottenhoff,Masoud Valiloo,Monika Sveclaet al. Nature Communications, 2023, 14 (1), pp.5181. ⟨10.1038/s41467-023-40943-1⟩ Article dans une revue hal-04208487v1
Germline JAK2 E846D Substitution as the Cause of Erythrocytosis? Nada Maaziz,Céline Garrec,Fabrice Airaud,Victor Bobée,Nathalie Contentinet al. Genes, 2023, 14 (5), pp.1066. ⟨10.3390/genes14051066⟩ Article dans une revue hal-04208496v1
Generation of an induced pluripotent stem cell line (ITXi012-A) from a patient with genetically determined high-lipoprotein(a) plasma levels Amandine Caillaud,Lise Bray,Aurore Girardeau,Zoé Begué-Racapé,Lucie Vinceet al. Stem Cell Research, 2023, 72, ⟨10.1016/j.scr.2023.103205⟩ Article dans une revue hal-04212298v1
In silico and Functional Studies for Classification of EPAS1/HIF2A Genetic Variants Identified in Patients with Erythrocytosis Valéna Karaghiannis,Darko Maric,Céline Garrec,Nada Maaziz,Alexandre Buffetet al. Blood, 2022, 140 (Supplement 1), pp.8157-8158. ⟨10.1182/blood-2022-163123⟩ Article dans une revue hal-04031832v1
Generation of a GPR146 knockout human induced pluripotent stem cell line (ITXi001-A-1) Lise Bray,Amandine Caillaud,Aurore Girardeau,Murielle Patitucci,Cédric Le Mayet al. Stem Cell Research, 2022, 60, pp.102721. ⟨10.1016/j.scr.2022.102721⟩ Article dans une revue hal-03869113v1
Intracranial Aneurysm Classifier Using Phenotypic Factors: An International Pooled Analysis Sandrine Morel,Isabel Hostettler,Georg Spinner,Romain Bourcier,Joanna Peraet al. Journal of Personalized Medicine, 2022, 12 (9), pp.1410. ⟨10.3390/jpm12091410⟩ Article dans une revue hal-04060055v1
Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome Paolo Zanoni,Grigorios Panteloglou,Alaa Othman,Joël T. Haas,Roger Meieret al. Circulation Research, 2022, 130 (1), pp.80-95. ⟨10.1161/CIRCRESAHA.120.318141⟩ Article dans une revue hal-03554168v1
Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion Willemien van Zwol,Antoine Antoine Rimbert,Justina C Wolters,Marieke Smit,Vincent W Blokset al. Hepatology, 2022, 23 (8), pp.n/a-n/a. ⟨10.1002/hep.32709⟩ Article dans une revue hal-04060059v1
APOB CRISPR-Cas9 Engineering in Hypobetalipoproteinemia: A Promising Tool for Functional Studies of Novel Variants Xavier Vanhoye,Alexandre Janin,Amandine Caillaud,Antoine Rimbert,Fabienne Venetet al. International Journal of Molecular Sciences, 2022, 23 (8), pp.4281. ⟨10.3390/ijms23084281⟩ Article dans une revue hal-03659209v1
FACS-assisted CRISPR-Cas9 genome editing of human induced pluripotent stem cells Amandine Caillaud,Antoine Lévêque,Aurélie Thédrez,Aurore Girardeau,Robin Canacet al. STAR Protocols, 2022, 3 (4), pp.101680. ⟨10.1016/j.xpro.2022.101680⟩ Article dans une revue hal-04060050v1
Large HDL particles negatively associate with leukocyte counts independent of cholesterol efflux capacity : a cross sectional study in the population-based LifeLines DEEP cohort Anouk Groenen,Venetia Bazioti,Isabelle van Zeventer,Lianmin Chen,Hilde Grootet al. Atherosclerosis, 2022, 343, pp.20-27. ⟨10.1016/j.atherosclerosis.2022.01.008⟩ Article dans une revue hal-04060061v1
Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia Wieneke Dijk,Mathilde Di-Filippo Charcosset,Sander Kooijman,Robin Van Eenige,Antoine Rimbertet al. Circulation, 2022, 146 (10), pp.724-739. ⟨10.1161/circulationaha.121.057978⟩ Article dans une revue inserm-03831077v1
The Genetic Spectrum of Familial Hypertriglyceridemia in Oman Khalid Al-Waili,Khalid Al-Rasadi,Muna Al-Bulushi,Mohammed Habais,Abdullah Al-Mujainiet al. Frontiers in Genetics, 2022, 13, ⟨10.3389/fgene.2022.886182⟩ Article dans une revue hal-04060049v1
A novel role for GalNAc-T2 dependent glycosylation in energy homeostasis Cristy R.C. Verzijl,Federico Oldoni,Natalia Loaiza,Justina Wolters,Antoine Rimbertet al. Molecular metabolism, 2022, 60 (1), pp.101472. ⟨10.1016/j.molmet.2022.101472⟩ Article dans une revue hal-04060053v1
Genetic Inhibition of PCSK9 and Liver Function Antoine Rimbert,Sarra Smati,Wieneke Dijk,Cedric Le May,Bertrand Cariou JAMA Cardiology, 2021, ⟨10.1001/jamacardio.2020.5341⟩ Article dans une revue hal-03100949v1
Routine use of statins and increased COVID-19 related mortality in inpatients with type 2 diabetes: Results from the CORONADO study Bertrand Cariou,Thomas Goronflot,Antoine Rimbert,Sandrine Boullu,Cedric Le Mayet al. Journal of Diabetes & Metabolism, 2021, 47 (2), pp.101202. ⟨10.1016/j.diabet.2020.10.001⟩ Article dans une revue hal-03100948v1
PCSK9 regulates the NODAL signaling pathway and cellular proliferation in hiPSCs Meryl Roudaut,Salam Idriss,Amandine Caillaud,Aurore Girardeau,Antoine Rimbertet al. Stem Cell Reports, 2021, ⟨10.1016/j.stemcr.2021.10.004⟩ Article dans une revue hal-03451184v1
Phenotypic Differences Between Polygenic and Monogenic Hypobetalipoproteinemia Antoine Rimbert,Xavier Vanhoye,Dramane Coulibaly,Marie Marrec,Matthieu Pichelinet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2021, 41 (1), pp.e63-e71. ⟨10.1161/ATVBAHA.120.315491⟩ Article dans une revue hal-03105646v1
Comprehensive &lt;i&gt;in silico&lt;/i&gt; and functional studies for classification of &lt;i&gt;EPAS1/HIF2A&lt;/i&gt; genetic variants identified in patients with erythrocytosis Valéna Karaghiannis,Darko Maric,Céline Garrec,Nada Maaziz,Alexandre Buffetet al. Haematologica, 2020, ⟨10.3324/haematol.2022.281698⟩ Article dans une revue hal-04060048v1
Taking One Step Back in Familial Hypercholesterolemia Natalia Loaiza,Merel Hartgers,Laurens Reeskamp,Jan-Willem Balder,Antoine Rimbertet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, 40 (4), pp.973-985. ⟨10.1161/ATVBAHA.119.313470⟩ Article dans une revue hal-02468286v1
Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids Adriaan van Der Graaf,Annique Claringbould,Antoine Rimbert,Harm-Jan Westra,Yang Liet al. Nature Communications, 2020, 11 (1), pp.4930. ⟨10.1038/s41467-020-18716-x⟩ Article dans une revue hal-02970789v1
GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis Haojie Yu,Antoine Rimbert,Alice Palmer,Takafumi Toyohara,Yulei Xiaet al. Cell, 2019, 179 (6), pp.1276-1288.e14. ⟨10.1016/j.cell.2019.10.034⟩ Article dans une revue hal-02422749v1
The Future of Lipid-Lowering Therapy Willemien Van Zwol,Antoine Rimbert,Jan Kuivenhoven Journal of Clinical Medicine, 2019, 8 (7), pp.1085. ⟨10.3390/jcm8071085⟩ Article dans une revue hal-02422745v1
A common variant in CCDC93 protects against myocardial infarction and cardiovascular mortality by regulating endosomal trafficking of low-density lipoprotein receptor Antoine Rimbert,Nawar Dalila,Justina Wolters,Nicolette Huijkman,Marieke Smitet al. European Heart Journal, 2019, ⟨10.1093/eurheartj/ehz727⟩ Article dans une revue hal-02422747v1
Use of plasma metabolomics to analyze phenotype-genotype relationships in young hypercholesterolemic females Xiang Zhang,Antoine Rimbert,Willem Balder,Aeilko Having Zwinderman,Jan Albert Kuivenhovenet al. Journal of Lipid Research, 2018, 59 (11), pp.2174-2180. ⟨10.1194/jlr.M088930⟩ Article dans une revue hal-02422741v1
Genetics of syndromic and non-syndromic mitral valve prolapse Thierry Le Tourneau,Jean Merot,Antoine Rimbert,Solena Le Scouarnec,Vincent Probstet al. Heart, 2018, 104 (12), pp.978-984. ⟨10.1136/heartjnl-2017-312420⟩ Article dans une revue hal-04754059v1
Identification of novel APOB mutations by targeted next-generation sequencing for the molecular diagnosis of familial hypobetalipoproteinemia Antoine Rimbert,Matthieu Pichelin,Simon Lecointe,Marie Marrec,Solena Le Scouarnecet al. Atherosclerosis, 2016, Equipe 3 Equipe 4 Equipe 5, 250, pp.52--56. ⟨10.1016/j.atherosclerosis.2016.04.010⟩ Article dans une revue hal-01831745v1
Artériopathie et hétérogénéité artérielle Y. Gouëffic,J.-M. Davaine,T. Merlini,Antoine Rimbert,F. Hérissonet al. La Revue de Médecine Interne, 2013, 34 (1), pp.61-65. ⟨10.1016/j.revmed.2012.10.364⟩ Article dans une revue istex hal-05361509v1

Pré-publication, Document de travail (2)

Isolated prolapse of the posterior mitral valve leaflet: phenotypic refinement, heritability and genetic etiology Antoine Rimbert,Damien Duval,Daniel Trujillano,Florence Kyndt,Antoine Jobbé-Duvalet al. 2024 Pré-publication, Document de travail (preprint/prepublication) hal-04751125v1
MicroRNA-541-3p alters lipoproteins to reduce atherosclerosis by degrading Znf101 and Casz1 transcription factors Abulaish Ansari,Pradeep Kumar Yadav,Liye Zhou,Binu Prakash,Bhargavi Gangulaet al. 2024 Pré-publication, Document de travail hal-04759206v1