Arnaud Billet Maître de conférencesBTSB EA7417 INU Champollion

Publications

Article dans une revue (25)

A New Kv1.3 Channel Blocker from the Venom of the Ant Tetramorium bicarinatum Guillaume Boy,Laurence Jouvensal,Nathan Téné,Jean-Luc Carayon,Elsa Bonnaféet al. Toxins, 2025, 17 (8), pp.379. ⟨10.3390/toxins17080379⟩ Article dans une revue hal-05233382v1
Adaptive trade-offs between vertebrate defence and insect predation drive Amazonian ant venom evolution Axel Touchard,Samuel D Robinson,Hadrien Lalagüe,Steven Ascoët,Arnaud Billetet al. Proceedings of the Royal Society B: Biological Sciences, 2024, 291 (2035), pp.20242184. ⟨10.1098/rspb.2024.2184⟩ Article dans une revue hal-04795576v1
Isolation, NMR Characterization, and Bioactivity of a Flavonoid Triglycoside from Anthyllis henoniana Stems: Antioxidant and Antiproliferative Effects on MDA-MB-231 Breast Cancer Cells Amani Ayachi,Guillaume Boy,Sonda Samet,Nathan Téné,Bouthaina Bouzayaniet al. Antioxidants , 2024, 13 (7), pp.793. ⟨10.3390/antiox13070793⟩ Article dans une revue hal-04635159v1
The mechanism underlying toxicity of a venom peptide against insects reveals how ants are master at disrupting membranes Steven Ascoët,Axel Touchard,Nathan Téné,Benjamin Lefranc,Jérôme Leprinceet al. iScience, 2023, 26 (3), pp.106157. ⟨10.1016/j.isci.2023.106157⟩ Article dans une revue hal-04071274v1
The mechanism underlying toxicity of a venom peptide against insects reveals how ants are master at disrupting membranes Steven Ascoët,Axel Touchard,Nathan Téné,Benjamin Lefranc,Jérôme Leprinceet al. iScience, 2023, 26 (3), pp.106157. ⟨10.1016/j.isci.2023.106157⟩ Article dans une revue hal-05484980v1
Discovery of an Insect Neuroactive Helix Ring Peptide from Ant Venom Valentine Barassé,Laurence Jouvensal,Guillaume Boy,Arnaud Billet,Steven Ascoëtet al. Toxins, 2023, 15 (10), pp.600. ⟨10.3390/toxins15100600⟩ Article dans une revue hal-04390519v1
The multi-faceted nature of 15 CFTR exonic variations: Impact on their functional classification and perspectives for therapy Anne Bergougnoux,A. Billet,C. Ka,M. Heller,F. Degrugillieret al. Journal of Cystic Fibrosis, 2022, ⟨10.1016/j.jcf.2022.12.003⟩ Article dans une revue hal-03913493v1
The rescue of F508del-CFTR by elexacaftor/tezacaftor/ivacaftor (Trikafta) in human airway epithelial cells is underestimated due to the presence of ivacaftor Frédéric Becq,Sandra Mirval,Thomas Carrez,Manuella Lévêque,Arnaud Billetet al. European Respiratory Journal, 2022, 59 (2), pp.2100671. ⟨10.1183/13993003.00671-2021⟩ Article dans une revue hal-05605563v1
The rescue of F508del-CFTR by elexacaftor/tezacaftor/ivacaftor (Trikafta) in human airway epithelial cells is underestimated due to the presence of ivacaftor Frédéric Becq,Sandra Mirval,Thomas Carrez,Manuella Lévêque,Arnaud Billetet al. European Respiratory Journal, 2022, 59 (2), pp.2100671. ⟨10.1183/13993003.00671-2021⟩ Article dans une revue hal-04352015v1
Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity Lionel Froux,Ahmad Elbahnsi,Benjamin Boucherle,Arnaud Billet,Nesrine Baatallahet al. European Journal of Medicinal Chemistry, 2020, 190, pp.112116. ⟨10.1016/j.ejmech.2020.112116⟩ Article dans une revue hal-02924784v1
Functional and Pharmacological Characterization of the Rare CFTR Mutation W361R Arnaud Billet,Ahmad Elbahnsi,Mathilde Jollivet-Souchet,Brice Hoffmann,Jean-Paul Mornonet al. Frontiers in Pharmacology, 2020, 11, ⟨10.3389/fphar.2020.00295⟩ Article dans une revue hal-02557014v1
Pendrin mediates bicarbonate secretion and enhances CFTR function in airway surface epithelia Dusik Kim,Junwei Huang,Arnaud Billet,Asmahan Abu-Arish,Julie Goeppet al. American Journal of Respiratory Cell and Molecular Biology, 2019, 60 (6), pp.705-716. ⟨10.1165/rcmb.2018-0158OC⟩ Article dans une revue hal-03145546v1
Modulating the cystic fibrosis transmembrane regulator and the development of new precision drugs Lionel Froux,Arnaud Billet,Frédéric Becq Expert Review of Precision Medicine and Drug Development, 2018, 3 (6), pp.357-370. ⟨10.1080/23808993.2018.1547109⟩ Article dans une revue hal-03192898v1
Development of Automated Patch Clamp Technique to Investigate CFTR Chloride Channel Function Arnaud Billet,Lionel Froux,John Hanrahan,Frederic Becq Frontiers in Pharmacology, 2017, 8, pp.195. ⟨10.3389/fphar.2017.00195⟩ Article dans une revue hal-03191777v1
Low free drug concentration prevents inhibition of F508del CFTR functional expression by the potentiator VX-770 (ivacaftor) Elizabeth Matthes,Julie Goepp,Graeme Carlile,Yishan Luo,Kurt Dejgaardet al. British Journal of Pharmacology, 2016, 173 (3), pp.459-470. ⟨10.1111/bph.13365⟩ Article dans une revue hal-03193045v1
Potential sites of CFTR activation by tyrosine kinases Arnaud Billet,Yanlin Jia,Timothy Jensen,Yue-Xian Hou,Xiu-Bao Changet al. Channels, 2016, 10 (3), pp.247-251. ⟨10.1080/19336950.2015.1126010⟩ Article dans une revue hal-03192938v1
The dual phosphodiesterase 3 and 4 inhibitor RPL554 stimulates CFTR and ciliary beating in primary cultures of bronchial epithelia Mark Turner,Elizabeth Matthes,Arnaud Billet,Amy Ferguson,David Thomaset al. American Journal of Physiology - Lung Cellular and Molecular Physiology, 2016, 310 (1), pp.L59-L70. ⟨10.1152/ajplung.00324.2015⟩ Article dans une revue hal-03193027v1
Regulation of the cystic fibrosis transmembrane conductance regulator anion channel by tyrosine phosphorylation Arnaud Billet,John W Hanrahan FASEB Journal, 2015, 29 (9), pp.3945-3953. ⟨10.1096/fj.15-273151⟩ Article dans une revue hal-03192145v1
CFTR: Effect of ICL2 and ICL4 amino acids in close spatial proximity on the current properties of the channel Arnaud Billet,Jean-Paul Mornon,Mathilde Jollivet,Pierre Lehn,Isabelle Callebautet al. Journal of Cystic Fibrosis, 2013, 12, pp.737-745. ⟨10.1016/j.jcf.2013.02.002⟩ Article dans une revue istex hal-00907930v1
The secret life of CFTR as a calcium-activated chloride channel Arnaud Billet,John W Hanrahan The Journal of Physiology, 2013, 591 (21), pp.5273-5278. ⟨10.1113/jphysiol.2013.261909⟩ Article dans une revue hal-03192129v1
Role of Tyrosine Phosphorylation in the Muscarinic Activation of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Arnaud Billet,Yishan Luo,Haouaria Balghi,John Hanrahan Journal of Biological Chemistry, In press, 288 (30), pp.21815-21823. ⟨10.1074/jbc.M113.479360⟩ Article dans une revue hal-03191691v1
Stimulation of wild-type, F508del- and G551D-CFTR chloride channels by non-toxic modified pyrrolo[2,3-b]pyrazine derivatives Luc Dannhoffer,Arnaud Billet,Mathilde Jollivet-Souchet,Patricia Melin-Heschel,Christelle Faveauet al. Frontiers in Pharmacology, 2011, 2, ⟨10.3389/fphar.2011.00048⟩ Article dans une revue hal-03192023v1
C terminus of nucleotide binding domain 1 contains critical features for cystic fibrosis transmembrane conductance regulator trafficking and activation. Arnaud Billet,Patricia Melin,Mathilde Jollivet,Jean-Paul Mornon,Isabelle Callebautet al. Journal of Biological Chemistry, 2010, 285 (29), pp.22132-40. ⟨10.1074/jbc.M110.120683⟩ Article dans une revue hal-00582442v1
Understanding nucleotide binding and CFTR ion channel gating: how many cycles? Frédéric Becq,Arnaud Billet Expert Review of Respiratory Medicine, 2010, 4 (4), pp.451-4. ⟨10.1586/ers.10.47⟩ Article dans une revue hal-00561612v1
Identification of a novel water-soluble activator of wild-type and F508del CFTR: GPact-11a. J. Bertrand,B. Boucherle,A. Billet,P. Melin-Heschel,L. Dannhofferet al. European Respiratory Journal, 2010, 36 (2), pp.311-22. ⟨10.1183/09031936.00122509⟩ Article dans une revue hal-00559199v1