Asuncion Carmona

Publications

Article dans une revue (58)

Synchrotron-based correlative imaging of metals and proteins in neuronal cells: state of the art and future challenges in neurometallomics Ines Kelkoul,Virginia Puente Muñoz,Richard Ortega,Asuncion Carmona Metallomics, 2025, 17 (2), pp.mfaf003. ⟨10.1093/mtomcs/mfaf003⟩ Article dans une revue hal-04975566v1
Storage and transport of labile iron is mediated by lysosomes in axons and dendrites of hippocampal neurons Aiyarin Kittilukkana,Asuncion Carmona,Léa Normand,Coline Gibout,Andrea Somogyiet al. Metallomics, 2025, 17 (7), pp.mfaf021. ⟨10.1093/mtomcs/mfaf021⟩ Article dans une revue hal-05174176v1
Metal dyshomeostasis in the substantia nigra of patients with Parkinson's disease or multiple sclerosis Asuncion Carmona,Eleonora Carboni,Lucas Caldi Gomes,Stéphane Roudeau,Fabian Maasset al. J.Neurochem., 2024, 168 (2), pp.128-141. ⟨10.1111/jnc.16040⟩ Article dans une revue hal-04399792v1
TauSTED super-resolution imaging of labile iron in primary hippocampal neurons Aiyarin Kittilukkana,Asuncion Carmona,Chalermchai Pilapong,Richard Ortega Metallomics, 2024, 16 (1), pp.mfad074. ⟨10.1093/mtomcs/mfad074⟩ Article dans une revue hal-04384472v1
Native Cryo-Correlative Light and Synchrotron X-ray Fluorescence Imaging of Proteins and Essential Metals in Subcellular Neuronal Compartments Richard Ortega,Mónica Fernández‐monreal,Noémie Pied,Stéphane Roudeau,Peter Cloetenset al. Chemical & Biomedical Imaging, 2024, 2 (11), pp.744-754. ⟨10.1021/cbmi.4c00038⟩ Article dans une revue hal-04680903v1
Multimodal and multiscale correlative elemental imaging: From whole tissues down to organelles Stéphane Roudeau,Asuncion Carmona,Richard Ortega Curr.Opin.Chem.Biol., 2023, 76, pp.102372. ⟨10.1016/j.cbpa.2023.102372⟩ Article dans une revue hal-04170464v1
Correlative nano-imaging of metals and proteins in primary neurons by synchrotron X-ray fluorescence and STED super resolution microscopy: Experimental validation Richard Ortega,Stéphane Roudeau,Asuncion Carmona J.Neurosci.Methods, 2022, 381, pp.109702. ⟨10.1016/j.jneumeth.2022.109702⟩ Article dans une revue hal-03771841v1
Imaging the structural organization of chemical elements in growth cones of developing hippocampal neurons Asuncion Carmona,Si Chen,Florelle Domart,Daniel Choquet,Richard Ortega Metallomics, 2022, 14 (1), pp.mfab073. ⟨10.1093/mtomcs/mfab073⟩ Article dans une revue hal-03526688v1
Neurotoxicity of Environmental Metal Toxicants: Special Issue Richard Ortega,Asuncion Carmona Toxics, 2022, 10 (7), pp.382. ⟨10.3390/toxics10070382⟩ Article dans une revue hal-03738833v1
Altered SOD1 maturation and post-translational modification in amyotrophic lateral sclerosis spinal cord Benjamin G. Trist,Sian Genoud,Stéphane Roudeau,Alexander Rookyard,Amr Abdeenet al. Brain, 2022, 145 (9), pp.3108-3130. ⟨10.1093/brain/awac165⟩ Article dans une revue hal-03764277v1
Cytoplasmic aggregation of uranium in human dopaminergic cells after continuous exposure to soluble uranyl at non-cytotoxic concentrations Asuncion Carmona,Francesco Porcaro,Andrea Somogyi,Stéphane Roudeau,Florelle Domartet al. NeuroToxicology, 2021, 82, pp.35-44. ⟨10.1016/j.neuro.2020.10.015⟩ Article dans une revue hal-03066343v1
How much manganese is safe for infants? A review of the scientific basis of intake guidelines and regulations relevant to the manganese content of infant formulas Erika J. Mitchell,Seth H. Frisbie,Stéphane Roudeau,Asuncion Carmona,Richard Ortega Journal of Trace Elements in Medicine and Biology, 2021, 65, pp.126710. ⟨10.1016/j.jtemb.2020.126710⟩ Article dans une revue hal-03115779v1
Native Separation and Metallation Analysis of SOD1 Protein from the Human Central Nervous System: a Methodological Workflow Stéphane Roudeau,Benjamin G. Trist,Asuncion Carmona,Katherine M. Davies,Glenda M. Hallidayet al. Analytical Chemistry, 2021, 93 (32), pp.11108-11115. ⟨10.1021/acs.analchem.1c01128⟩ Article dans une revue hal-03326181v1
Molecular Mechanisms of Environmental Metal Neurotoxicity: A Focus on the Interactions of Metals with Synapse Structure and Function Asuncion Carmona,Stéphane Roudeau,Richard Ortega Toxics, 2021, 9 (9), pp.198. ⟨10.3390/toxics9090198⟩ Article dans une revue hal-03342577v1
Correlating STED and synchrotron XRF nano-imaging unveils the cosegregation of metals and cytoskeleton proteins in dendrites Florelle Domart,Peter Cloetens,Stéphane Roudeau,Asuncion Carmona,Emeline Verdieret al. eLife, 2020, 9, pp.e62334. ⟨10.7554/eLife.62334⟩ Article dans une revue hal-03066339v1
Estimating daily intakes of manganese due to breast milk, infant formulas, or young child nutritional beverages in the United States and France: Comparison to sufficiency and toxicity thresholds Erika J. Mitchell,Seth H. Frisbie,Stéphane Roudeau,Asuncion Carmona,Richard Ortega Journal of Trace Elements in Medicine and Biology, 2020, 62, pp.126607. ⟨10.1016/j.jtemb.2020.126607⟩ Article dans une revue hal-03066344v1
Emerging chemical tools and techniques for tracking biological manganese Sayani Das,Kaustav Khatua,Ananya Rakshit,Asuncion Carmona,Anindita Sarkaret al. Dalton Trans., 2019, 48 (21), pp.7047-7061. ⟨10.1039/c9dt00508k⟩ Article dans une revue hal-02188086v1
SLC30A10 Mutation Involved in Parkinsonism Results in Manganese Accumulation within Nanovesicles of the Golgi Apparatus Asuncion Carmona,Charles E. Zogzas,Stéphane Roudeau,Francesco Porcaro,Jan Garrevoetet al. ACS Chem.Neurosci., 2019, 10 (1), pp.599-609. ⟨10.1021/acschemneuro.8b00451⟩ Article dans une revue hal-02017059v1
Manganese levels in infant formula and young child nutritional beverages in the United States and France: Comparison to breast milk and regulations Seth Frisbie,Erika Mitchell,Stéphane Roudeau,Florelle Domart,Asunción Carmonaet al. PLoS ONE, 2019, 14 (11), pp.e0223636. ⟨10.1371/journal.pone.0223636⟩ Article dans une revue hal-02351030v1
Mapping Chemical Elements and Iron Oxidation States in the Substantia Nigra of 6-Hydroxydopamine Lesioned Rats Using Correlative Immunohistochemistry With Proton and Synchrotron Micro-Analysis Asuncion Carmona,Stéphane Roudeau,Laura Perrin,Carole Carcenac,Delphine Vantelonet al. Front.Neurosci., 2019, 13, pp.1014. ⟨10.3389/fnins.2019.01014⟩ Article dans une revue hal-02327769v1
Manganese Mapping Using a Fluorescent Mn 2+ Sensor and Nanosynchrotron X-ray Fluorescence Reveals the Role of the Golgi Apparatus as a Manganese Storage Site Sayani Das,Asuncion Carmona,Kaustav Khatua,Francesco Porcaro,Andrea Somogyiet al. Inorganic Chemistry, 2019, 58 (20), pp.13724-13732. ⟨10.1021/acs.inorgchem.9b01389⟩ Article dans une revue hal-02349653v1
Uranium exposure of human dopaminergic cells results in low cytotoxicity, accumulation within sub-cytoplasmic regions, and down regulation of MAO-B A. Carmona,Veronique Malard,E. Avazeri,S. Roudeau,F. Porcaroet al. NeuroToxicology, 2018, 68, pp.177-188. ⟨10.1016/j.neuro.2018.07.019⟩ Article dans une revue cea-02339669v1
Advances in element speciation analysis of biomedical samples using synchrotron-based techniques Francesco Porcaro,Stéphane Roudeau,Asunción Carmona,Richard Ortega Trends in Analytical Chemistry, 2018, 104, pp.22-41. ⟨10.1016/j.trac.2017.09.016⟩ Article dans une revue hal-01905442v1
Amyotrophic lateral sclerosis-like superoxide dismutase 1 proteinopathy is associated with neuronal loss in Parkinson’s disease brain Benjamin G. Trist,Katherine M. Davies,Veronica Cottam,Sian Genoud,Richard Ortegaet al. Acta Neuropathol., 2017, 134 (1), pp.113-127. ⟨10.1007/s00401-017-1726-6⟩ Article dans une revue hal-01729986v1
Growth, Duplication and Lateral Mutual Compressive Deformation of Akouemma hemisphaeria on the Seafloor of Okondja Basin at 2.2 Ga (Gabon) Ambroise Edou- Minko,Mathieu Moussavou,Tomohiko Sato,Yusuke Sawaki,Simplice Ndong Ondoet al. International Journal of Geosciences, 2017, 08 (09), pp.1172-1191. ⟨10.4236/ijg.2017.89067⟩ Article dans une revue hal-02900108v1
Heterogeneous intratumoral distribution of gadolinium nanoparticles within U87 human glioblastoma xenografts unveiled by micro-PIXE imaging Asuncion Carmona,Stéphane Roudeau,Baptiste L'Homel,Frédéric Pouzoulet,Sarah Bonnet-Boissinotet al. Anal.Biochem., 2017, 523, pp.50-57. ⟨10.1016/j.ab.2017.02.010⟩ Article dans une revue hal-01758229v1
Zinc and Copper Effects on Stability of Tubulin and Actin Networks in Dendrites and Spines of Hippocampal Neurons Laura Perrin,Stéphane Roudeau,Asuncion Carmona,Florelle Domart,Jennifer D. Petersenet al. ACS Chem.Neurosci., 2017, 8 (7), pp.1490-1499. ⟨10.1021/acschemneuro.6b00452⟩ Article dans une revue hal-01719686v1
An Akouemma hemisphaeria Organic Macrofossils Colony Hosting Biodiversity Assemblage on the Seafloor of Okondja Basin (Gabon) dated at 2.2 Ga A Edou-Minko,M Moussavou,T Sato,C Tchikoundzi,Y Sawakiet al. New Zealand Journal of Geology and Geophysics, 2017, 06 (02), ⟨10.4172/2381-8719.1000281⟩ Article dans une revue hal-02900111v1
α-Synuclein Over-Expression Induces Increased Iron Accumulation and Redistribution in Iron-Exposed Neurons Richard Ortega,Asuncion Carmona,Stéphane Roudeau,Laura Perrin,Tanja Dučićet al. Molecular Neurobiology, 2015, 53 (3), pp.1925-1934. ⟨10.1007/s12035-015-9146-x⟩ Article dans une revue hal-01758781v1
Multicellular Consortia Preserved in Biogenic Ductile-Plastic Nodules of Okondja Basin (Gabon) by 2.1 Ga Moussavou Edou Minko A,Mathieu Moussavou,Ambroise Edou-Minko,M Mbina Mounguengui,Richard Ortegaet al. Journal of Geology & Geosciences, 2015, 04 (02), ⟨10.4172/2329-6755.1000195⟩ Article dans une revue hal-02900118v1
Reduced net charge and heterogeneity of pI isoforms in familial amyotrophic lateral sclerosis mutants of copper/zinc superoxide dismutase Stephane Roudeau,Sylviane Chevreux,Asunción Carmona,Richard Ortega Electrophoresis, 2015, 36 (19), pp.2482-2488. ⟨10.1002/elps.201500187⟩ Article dans une revue istex hal-02899586v1
Evaluation of sample preparation methods for single cell quantitative elemental imaging using proton or synchrotron radiation focused beams Laura Perrin,Asuncion Carmona,Stéphane Roudeau,Richard Ortega Journal of Analytical Atomic Spectrometry, 2015, 30 (12), pp.2525-2532. ⟨10.1039/C5JA00303B⟩ Article dans une revue hal-02899701v1
Analysis of Platinum and Trace Metals in Treated Glioma Rat Cells by X-Ray Fluorescence Emission Silvia Gil,Asuncion Carmona,Gema Martinez-Criado,Alberto Leon,Yolanda Prezadoet al. Biological Trace Element Research, 2015, 163 (1-2), pp.177-183. ⟨10.1007/s12011-014-0097-2⟩ Article dans une revue hal-02899952v1
Environmental manganese compounds accumulate as Mn(II) within the Golgi apparatus of dopamine cells: relationship between speciation, subcellular distribution, and cytotoxicity A. Carmona,S. Roudeau,L. Perrin,G. Veronesi,R. Ortega Metallomics, 2014, 6, pp.822-832. ⟨10.1039/C4MT00012A⟩ Article dans une revue in2p3-01020559v1
Improvement and recent applications of the Tohoku microbeam system S. Matsuyama,K. Ishii,K. Watanabe,A. Terakawa,Y. Kikuchiet al. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2014, 318, pp.32-36. ⟨10.1016/j.nimb.2013.06.056⟩ Article dans une revue istex in2p3-00977087v1
Copper pathology in vulnerable brain regions in Parkinson's disease. Katherine M. Davies,Sylvain Bohic,Asunción Carmona,Richard Ortega,Veronica Cottamet al. Neurobiol Aging, 2014, 35 (4), pp.858-66. ⟨10.1016/j.neurobiolaging.2013.09.034⟩ Article dans une revue inserm-00968923v1
Correlative organelle fluorescence microscopy and synchrotron X-ray chemical element imaging in single cells Stephane Roudeau,Asuncion Carmona,Laura Perrin,Richard Ortega Analytical and Bioanalytical Chemistry, 2014, 406 (27), pp.6979-6991. ⟨10.1007/s00216-014-8004-4⟩ Article dans une revue hal-02899959v1
Low-solubility particles and a Trojan-horse type mechanism of toxicity: the case of cobalt oxide on human lung cells Richard Ortega,Carole Bresson,Carine Darolles,Celine C. Gautier,Stéphane Roudeauet al. Particle and Fibre Toxicology, 2014, 11 (1), pp.14. ⟨10.1186/1743-8977-11-14⟩ Article dans une revue hal-02899990v1
Cobalt chloride speciation, mechanisms of cytotoxicity on human pulmonary cells, and synergistic toxicity with zinc. C. Bresson,C. Darolles,A. Carmona,Christian Gautier,N. Sageet al. Toxicology Letters, 2013, 221, pp.0378-4274. ⟨10.1016/j.toxlet.2013.05.363⟩ Article dans une revue istex in2p3-00873216v1
Cobalt chloride speciation, mechanisms of cytotoxicity on human pulmonary cells, and synergistic toxicity with zinc C. Bresson,C. Darolles,A. Carmona,C. Gautier,N. Sageet al. Metallomics, 2013, 5, pp.133-143. ⟨10.1039/C3MT20196A⟩ Article dans une revue in2p3-00823540v1
X-ray absorption spectroscopy of biological samples. A tutorial R. Ortega,A. Carmona,I. Llorens,P. L. Solari Journal of Analytical Atomic Spectrometry, 2012, 27, pp.2054-2065. ⟨10.1039/c2ja30224a⟩ Article dans une revue in2p3-00767655v1
High Spatial Resolution Chemical Imaging of Inorganic and Organometallic Pesticides R. Ortega,A. Carmona Journal of Environmental & Analytical Toxicology, 2012, 4, pp.005. ⟨10.4172/2161-0525.S4-005⟩ Article dans une revue in2p3-00776225v1
Combined use of hard X-ray phase contrast imaging and X-ray fluorescence microscopy for sub-cellular metal quantification. Ewelina Kosior,Sylvain Bohic,Heikki Suhonen,Richard Ortega,Guillaume Devèset al. Journal of Structural Biology, 2012, 177 (2), pp.239-47. ⟨10.1016/j.jsb.2011.12.005⟩ Article dans une revue inserm-00662829v1
Coupling of native IEF and extended X-ray absorption fine structure to characterize zinc-binding sites from pI isoforms of SOD1 and A4V pathogenic mutant S. Chevreux,I. Llorens,P. Lorenzo Solari,S. Roudeau,Guillaume Devèset al. Electrophoresis, 2012, 33, pp.1276-1281. ⟨10.1002/elps.201100596⟩ Article dans une revue in2p3-00699389v1
Manganese Accumulates within Golgi Apparatus in Dopaminergic Cells as Revealed by Synchrotron X-ray Fluorescence Nanoimaging Asuncion Carmona,Guillaume Devès,Stéphane Roudeau,Peter Cloetens,Sylvain Bohicet al. ACS Chemical Neuroscience, 2010, 1 (3), pp.194-203. ⟨10.1021/cn900021z⟩ Article dans une revue inserm-00522281v1
Fluorine microimaging and quantification using nuclear reaction analysis: A tool for validating tissue distribution of positron emission tomography tracers G. Devès,S. Roudeau,Asuncion Carmona,S. Lavielle,K. Gionnetet al. Applied Physics Letters, 2009, 95 (2), pp.023701. ⟨10.1063/1.3173808⟩ Article dans une revue hal-02900009v1
Multimodal analysis of metals in copper-zinc superoxide dismutase isoforms separated on electrophoresis gels S. Chevreux,S. Roudeau,A. Fraysse,A. Carmona,Guillaume Devèset al. Biochimie, 2009, 91 (10), pp.1324--1327. ⟨10.1016/j.biochi.2009.05.016⟩ Article dans une revue istex hal-01560752v1
Bio-metals imaging and speciation in cells using proton and synchrotron radiation X-ray micro-spectroscopy R. Ortega,Guillaume Devès,A. Carmona Journal of the Royal Society Interface, 2009, 6, pp.S649-S658. ⟨10.1098/rsif.2009.0166.focus⟩ Article dans une revue in2p3-00762347v1
Direct speciation of metals in copper-zinc superoxide dismutase isoforms on electrophoresis gels using X-ray absorption near edge structure Sylviane Chevreux,Stéphane Roudeau,Aurélien Fraysse,Asuncion Carmona,Guillaume Devèset al. Journal of Analytical Atomic Spectrometry, 2008, 23 (8), pp.1117. ⟨10.1039/B802375A⟩ Article dans une revue istex hal-02900050v1
Nano-imaging of trace metals by synchrotron X-ray fluorescence into dopaminergic single cells and neurite-like processes Asuncion Carmona,Peter Cloetens,Guillaume Devès,Sylvain Bohic,Richard Ortega Journal of Analytical Atomic Spectrometry, 2008, 23 (8), pp.1083. ⟨10.1039/B802242A⟩ Article dans une revue istex hal-02900086v1
Accelerator-based research activities at “Centro Nacional de Aceleradores”, Seville (Spain) M.A. Respaldiza,F.J. Ager,A. Carmona,J. Ferrer,M. García-Leónet al. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2008, 266 (10), pp.2105-2109. ⟨10.1016/j.nimb.2008.02.080⟩ Article dans une revue istex hal-02900096v1
Quantitative micro-analysis of metal ions in subcellular compartments of cultured dopaminergic cells by combination of three ion beam techniques A. Carmona,G. Devès,R. Ortega Analytical and Bioanalytical Chemistry, 2008, 390 (6), pp.1585-1594. ⟨10.1007/s00216-008-1866-6⟩ Article dans une revue istex hal-02900090v1
Iron Storage within Dopamine Neurovesicles Revealed by Chemical Nano-Imaging Richard Ortega,Peter Cloetens,Guillaume Devès,Asuncion Carmona,Sylvain Bohic PLoS ONE, 2007, 2(9), pp.e925. ⟨10.1371/journal.pone.0000925⟩ Article dans une revue hal-00199671v1
Subcellular speciation analysis of trace element oxidation states using synchrotron radiation micro-X-ray absorption near-edge structure. Thomas Bacquart,Guillaume Devès,Asunción Carmona,Rémi Tucoulou,Sylvain Bohicet al. Analytical Chemistry, 2007, 79 (19), pp.7353-9. ⟨10.1021/ac0711135⟩ Article dans une revue inserm-00383852v1
Subcellular Speciation Analysis of Trace Element Oxidation States Using Synchrotron Radiation Micro-X-ray Absorption Near-Edge Structure Thomas Bacquart,Guillaume Devès,Asunción Carmona,Rémi Tucoulou,Sylvain Bohicet al. Analytical Chemistry, 2007, 79 (19), pp.7353 -7359. ⟨10.1021/ac0711135S0003-2700(07)01113-4⟩ Article dans une revue hal-00199708v1
Iron storage within dopamine neurovesicles revealed by chemical nano-imaging. Richard Ortega,Peter Cloetens,Guillaume Devès,Asunción Carmona,Sylvain Bohic PLoS ONE, 2007, 2 (9), pp.e925. ⟨10.1371/journal.pone.0000925⟩ Article dans une revue inserm-00383874v1
Identifying elements in rocks from the Dry Valleys desert (Antarctica) by ion beam proton induced X-ray emission J. Wierzchos,C. Ascaso,F.J. Ager,I. García-Orellana,A. Carmona-Luqueet al. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2006, 249 (1-2), pp.571-574. ⟨10.1016/j.nimb.2006.03.057⟩ Article dans une revue istex hal-02900102v1
Nuclear microprobe determination of platinum quantitative distribution in rat brain tumors after cisplatin or carboplatin injection for PAT treatment of glioma Richard Ortega,Marie-Claude Biston,Guillaume Devès,Sylvain Bohic,Asuncion Carmona Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2005, 231 (1-4), pp.321. ⟨10.1016/j.nimb.2005.01.077⟩ Article dans une revue istex hal-00139175v1