Aurélien LEBRUN Ingénieur d'Etudes Hors Classe en RMN

Identifiants chercheurs

IdHAL :

aurelien-lebrun

ORCID :

0000-0002-0801-9684

IdRef :

076433285

Présentation

Responsable d'un spectromètre RMN liquide 600 MHz équipé d'une cryoplateforme Prodigy avec cryosonde TCI.

Responsable de 2 spectromètres RMN liquide 400 MHz en libre accès.

Elucidation de structure de molécules organiques (substances naturelles, molécules issues de synthèse)

Publications

Article dans une revue (43)

Catalyst Selection for Body-Temperature Curable Polyurethane Networks from Poly(δ-Decalactone) and Lysine Diisocyanate Marine Boursier,Aurelien Lebrun,Karine Parra,Sylvain Caillol,Julien Pinaudet al. Polymers, 2025, 17, pp.2548. ⟨10.3390/polym17182548⟩ Article dans une revue hal-05271415v1
From slag to structure: Formation of novel iron oxalate crystals via Cyrene™-driven microwave chemistry Limor Ben Neon,Aurelien Lebrun,Eddy Petit,Anne Julbe Materialia, 2025, 41, pp.102443. ⟨10.1016/j.mtla.2025.102443⟩ Article dans une revue hal-05090848v1
Third‐Generation CD73 Inhibitors Based on a 4,6‐Disubstituted‐2‐Thiopyridine Scaffold Félix Grosjean,Maria Shaldaeva,Emeline Cros-Perrial,Céline Rodriguez,Rayane Ghoteimiet al. ChemMedChem, 2025, ⟨10.1002/cmdc.202400662⟩ Article dans une revue hal-04879866v1
Double Gyroid‐Forming Hybrid Anion Exchange Membranes With Superior Mechanical Properties Maximilien Coronas,Jason Richard,Eddy Petit,Aurélien Lebrun,Camille Bakkali Hassaniet al. Journal of Polymer Science, In press, ⟨10.1002/pol.20250675⟩ Article dans une revue hal-05356958v1
Highly Flexible 3D Printed Gelatin-Pluronic F127 Scaffolds Seeded with Schwann Cells toward Nerve Regeneration Sacha Barberat,Sakthivel Nagarajan,Michel Habib,Aurélien Lebrun,Naomi Nieswicet al. ACS Biomaterials Science and Engineering, 2025, 11 (9), pp.5498-5511. ⟨10.1021/acsbiomaterials.5c00479⟩ Article dans une revue hal-05326766v1
Revisiting the Role of Intramolecular Proton Donation in ATC Foldamer Catalysts for Asymmetric Nitro-Michael Reactions Audrey Gacogne,Julie Aguesseau-Kondrotas,Samantha Chaise,Jean‐Marc Campagne,Aurélien Lebrunet al. Advanced Synthesis and Catalysis, 2025, pp.e70156. ⟨10.1002/adsc.70156⟩ Article dans une revue hal-05406145v1
One‐Pot Synthesis of Bioinspired Peptide‐Decorated Apatite Nanoparticles for Nanomedicine Mathilde Guerin,Aurélien Lebrun,Liisa Kuhn,Thierry Azaïs,Guillaume P. Laurentet al. Small, 2024, 20 (8), pp.2306358. ⟨10.1002/smll.202306358⟩ Article dans une revue hal-04295040v1
Selective acylation of chitosan oligomers by several cyclic anhydrides as a 13C NMR quantification method Paul Morandi,Steve Berthalon,Ghislain David,Aurelien Lebrun,Karine Parraet al. Carbohydrate Polymer Technologies and Applications, 2024, 7, pp.100498. ⟨10.1016/j.carpta.2024.100498⟩ Article dans une revue hal-04990543v1
Star poly(lactide-co-glycolide) and poly(ε-caprolactone) polyurethanes with shape memory properties for biomedical applications Gaëlle Savin,Iliass Kadmiri,Sylvain Caillol,Philippe Gonzalez,Aurélien Lebrunet al. European Polymer Journal, 2024, 220, pp.113442. ⟨10.1016/j.eurpolymj.2024.113442⟩ Article dans une revue hal-04699510v1
Fast and Cost‐Efficient 17 O‐Isotopic Labeling of Carboxylic Groups in Biomolecules: From Free Amino Acids to Peptide Chains Jessica Špačková,Ieva Goldberga,Rishit Yadav,Guillaume Cazals,Aurélien Lebrunet al. Chemistry - A European Journal, 2023, 29 (10), pp.e202203014. ⟨10.1002/chem.202203014⟩ Article dans une revue hal-04002744v1
Paving the Way towards Sustainability of Polyurethanes: Synthesis and Properties of Terpene-Based Diisocyanate Aliénor Delavarde,Sebastien Lemouzy,Aurélien Lebrun,Julien Pinaud,Sylvain Caillol Molecules, 2023, 28 (20), pp.7133. ⟨10.3390/molecules28207133⟩ Article dans une revue hal-04246489v1
Mapping the N-Terminal Hexokinase-I Binding Site onto Voltage-Dependent Anion Channel-1 To Block Peripheral Nerve Demyelination Benoit Gautier,Mélanie Forêt Jacquard,Sophie Guelfi,Scarlette Abbou,Elisa Gonzalezet al. Journal of Medicinal Chemistry, 2022, 65 (17), pp.11633-11647. ⟨10.1021/acs.jmedchem.2c00411⟩ Article dans une revue hal-03987562v1
Fluorescent Dynamic Covalent Polymers for DNA Complexation and Templated Assembly Clément Kotras,Maxime Leclercq,Maxime Roger,Camille Bouillon,Antonio Recupidoet al. Molecules, 2022, 27 (19), pp.6648. ⟨10.3390/molecules27196648⟩ Article dans une revue hal-03832051v1
Vegetable oil-based hybrid microparticles as a green and biocompatible system for subcutaneous drug delivery Koceïla Doufène,Ilaria Basile,Aurélien Lebrun,Nelly Pirot,Aurélie Escandeet al. International Journal of Pharmaceutics, 2021, 592, pp.120070. ⟨10.1016/j.ijpharm.2020.120070⟩ Article dans une revue hal-03110144v1
Cost-efficient and user-friendly 17O/ 18O labeling procedures of fatty acids using mechanochemistry Jessica Špačková,Charlyn Fabra,Guillaume Cazals,Marie Hubert-Roux,Isabelle Schmitz-Afonsoet al. Chemical Communications, 2021, 57 (55), pp.6812-6815. ⟨10.1039/D1CC02165F⟩ Article dans une revue hal-03322217v1
A Novel Sesquiterpene Lactone Xanthatin-13-(pyrrolidine-2-carboxylic acid) Isolated from Burdock Leaf Up-Regulates Cells’ Oxidative Stress Defense Pathway Yanis A Idres,Didier Tousch,Guillaume Cazals,Aurélien Lebrun,Sarah Naceriet al. Antioxidants , 2021, 10 (10), ⟨10.3390/antiox10101617⟩ Article dans une revue hal-03434251v1
Synthesis, Characterization and Encapsulation Properties of Rigid and Flexible Porphyrin Cages Assembled from N-Heterocyclic Carbene-Metal Bonds Ludivine Poyac,Clémence Rose,Mohammad Wahiduzzaman,Aurélien Lebrun,Guillaume Cazalset al. Inorganic Chemistry, 2021, 60 (24), pp.19009-19021. ⟨10.1021/acs.inorgchem.1c02868⟩ Article dans une revue hal-03518954v1
Inorganic Sol−Gel Polymerization for Hydrogel Bioprinting Titouan Montheil,Marie Maumus,Laurine Valot,Aurélien Lebrun,Jean Martínezet al. ACS Omega, 2020, 5 (6), pp.2640-2647. ⟨10.1021/acsomega.9b03100⟩ Article dans une revue hal-02513894v1
Molecular complexes and main-chain organometallic polymers based on Janus bis(carbenes) fused to metalloporphyrins Jean-François Longevial,Mamadou Lo,Aurélien Lebrun,Danielle Laurencin,Sébastien Clémentet al. Dalton Transactions, In press, 49, pp.7005-7014. ⟨10.1039/D0DT00594K⟩ Article dans une revue hal-02568903v1
DNA‐Based Asymmetric Inverse Electron‐Demand Hetero‐Diels–Alder Justine Mansot,Jimmy Lauberteaux,Aurélien Lebrun,Marc Mauduit,Jean-Jacques Vasseuret al. Chemistry - A European Journal, 2020, 26 (16), pp.3519-3523. ⟨10.1002/chem.202000516⟩ Article dans une revue hal-02512892v1
Unveiling the Structure and Reactivity of Fatty-Acid Based (Nano)materials Thanks to Efficient and Scalable 17O and 18O-Isotopic Labeling Schemes Jessica Špačková,Charlyn Fabra,Sébastien Mittelette,Emeline Gaillard,Chia-Hsin Chenet al. Journal of the American Chemical Society, 2020, 142 (50), pp.21068-21081. ⟨10.1021/jacs.0c09383⟩ Article dans une revue hal-03117231v1
Iron-Catalyzed Enantioselective Intramolecular Inverse Electron-Demand Hetero Diels–Alder Reactions: An Access to Bicyclic Dihydropyran Derivatives Jimmy Lauberteaux,Aurélien Lebrun,Arie van Der Lee,Marc Mauduit,Renata Marcia de Figueiredoet al. Organic Letters, 2019, 21 (24), pp.10007-10012. ⟨10.1021/acs.orglett.9b03752⟩ Article dans une revue hal-02429682v1
Vinyl-aziridines and cyclopropanes in Pd-catalyzed (3+2)-cycloaddition reactions with cyclic N-sulfonyl imines Kim Spielmann,Eleonora Tosi,Aurélien Lebrun,Gilles Niel,Arie van Der Leeet al. Tetrahedron, 2018, 74 (45), pp.6497 - 6511. ⟨10.1016/j.tet.2018.09.040⟩ Article dans une revue hal-01892430v1
Cofacial porphyrin dimers assembled from N-heterocyclic carbene–metal bonds Clémence Rose,Aurélien Lebrun,Sébastien Clément,Sébastien Richeter Chemical Communications, 2018, 54 (69), pp.9603 - 9606. ⟨10.1039/C8CC05707A⟩ Article dans une revue hal-01862544v1
Fused Bis-lactams to Spirolactams: A New Member of the Family of Ring- Contraction Reaction Guilhem Chaubet,Mathéo Berthet,Morgane Pasco,Guillaume Cazals,Aurelien Lebrunet al. Letters in Organic Chemistry, 2018, 15 (12), pp.1046-1055. ⟨10.2174/1570178615666180326160131⟩ Article dans une revue hal-02388789v1
A multinuclear NMR perspective on the complexation between bisboronic acids and bisbenzoxaboroles with cis -diols Adèle Larcher,Aurélien Lebrun,Michael Smietana,Danielle Laurencin New Journal of Chemistry, 2018, 42 (4), pp.2815 - 2823. ⟨10.1039/C7NJ04143H⟩ Article dans une revue hal-01708542v1
Porphyrins Conjugated with Peripheral Thiolato Gold(I) Complexes for Enhanced Photodynamic Therapy Jean-François Longevial,Khaled El cheikh,Dina Aggad,Aurélien Lebrun,Arie Van der leeet al. Chemistry - A European Journal, 2017, 23, pp.14017-14026. ⟨10.1002/chem.201702975⟩ Article dans une revue hal-01613027v1
Hydrophobic alpha,alpha-Disubstituted Disilylated TESDpg Induces Incipient 3 10 -Helix in Short Tripeptide Sequence Roberto Fanelli,Dorothée Berthomieu,Claude Didierjean,Abdelatif Doudouh,Aurélien Lebrunet al. Organic Letters, 2017, 19 (11), pp.2937 - 2940. ⟨10.1021/acs.orglett.7b01172⟩ Article dans une revue hal-01552320v1
Oxa-diketopiperazines: Access and Conformational Analysis of Potential Turn Inducers Mathéo Berthet,Aurélien Lebrun,Arnaud Martel,Thomas Cheviet,Jean Martinezet al. ChemistrySelect, 2017, 2 (21), pp.5824-5827. ⟨10.1002/slct.201701393⟩ Article dans une revue hal-02313808v1
A Catalytically Competent Terpene Synthase Inferred Using Ancestral Sequence Reconstruction Strategy Daniele Guzzetti,Aurelien Lebrun,Maeva Subileau,Estelle Grousseau,Eric Dubreucqet al. ACS Catalysis, 2016, 6 (8), pp.5345 - 5349. ⟨10.1021/acscatal.6b01332⟩ Article dans une revue hal-01506512v1
N-Pyrrolidine-based alpha/beta-peptides incorporating ABOC, a constrained bicyclic beta-amino acid, for asymmetric aldol reaction catalysis Pierre Milbeo,Kelly Maurent,Laure Moulat,Aurelien Lebrun,Claude Didierjeanet al. Tetrahedron, 2016, 72 (13), pp.1706-1715. ⟨10.1016/j.tet.2016.02.027⟩ Article dans une revue hal-01532027v1
Selenazolidine: a selenium containing proline surrogate in peptide science E. Cordeau,S. Cantel,D. Gagne,A. Lebrun,J. Martinezet al. Organic & Biomolecular Chemistry, 2016, 14 (34), pp.8101-8108. ⟨10.1039/C6OB01450J⟩ Article dans une revue hal-03564292v1
Synthesis under moderate pressure of 3-imidazo[1,2- a ]pyridinylidene pyrrol-2-ones Nicolas Masurier,Aurélien Lebrun,Damien Canitrot,Jean-Michel Chezal,Emmanuel Moreau Tetrahedron Letters, 2016, 57 (24), pp.2583-2586. ⟨10.1016/j.tetlet.2016.04.093⟩ Article dans une revue istex hal-03564389v1
Selective homodimerization of unprotected peptides using hybrid hydroxydimethylsilane derivatives Cécile Echalier,Alexandra Kalistratova,Jeremie Ciccione,Aurelien Lebrun,Baptiste Legrandet al. RSC Advances, 2016, ⟨10.1039/c6ra06075g⟩ Article dans une revue hal-01345976v1
Straightforward synthesis towards mono and bis-phosphonic acid functionalised β-cyclodextrins April Marquick,Jean-Louis Montero,Aurélien Lebrun,Véronique Barragan-Montero Tetrahedron, 2015, 71 (10), pp.1616-1621. ⟨10.1016/j.tet.2014.12.019⟩ Article dans une revue hal-03592418v1
Synthesis and structural characterization of monomeric and dimeric peptide nucleic acids prepared by using microwave-promoted multicomponent reactions Reuben Ovadia,Aurelien Lebrun,Ivan Barvik,Jean-Jacques Vasseur,Carine Baragueyet al. Organic & Biomolecular Chemistry, 2015, 13, pp.11052-11071. ⟨10.1039/c5ob01604e⟩ Article dans une revue hal-01438999v1
From Diketopiperazines to Hydantoins: An Unprecedented Rearrangement Guilhem Chaubet,Guillaume Cazals,Aurélien Lebrun,Jean Martinez,Isabelle Parrot SYNLETT, 2014, 25 (4), pp.574-578. ⟨10.1055/s-0033-1340622⟩ Article dans une revue hal-00951723v1
Thiazole-Based γ-Building Blocks as Reverse-Turn Mimetic to Design a Gramicidin S Analogue: Conformational and Biological Evaluation Baptiste Legrand,Loic Mathieu,Aurélien Lebrun,Soahary Andriamanarivo,Vincent Lisowskiet al. Chemistry - A European Journal, 2014, 20 (22), pp.6713-6720. ⟨10.1002/chem.201402190⟩ Article dans une revue istex hal-02912610v1
Silaproline Helical Mimetics Selectively Form an All-trans PPII Helix Charlotte Martin,Baptiste Legrand,Aurélien Lebrun,Dorothée Berthomieu,Jean Martinezet al. Chemistry - A European Journal, 2014, 20 (44), pp.1420-14244. ⟨10.1002/chem.201404820⟩ Article dans une revue istex hal-01078148v1
Synthesis of Homopolypeptides with PPII Structure Charlotte Martin,Aurélien Lebrun,Jean Martinez,Florine Cavelier Journal of Polymer Science, 2013, 51, pp.3103-3109. ⟨10.1002/pola.26705⟩ Article dans une revue istex hal-00838581v1
Stereoselective synthesis of original spirolactams displaying promising folded structures. Guilhem Chaubet,Thibault Coursindel,Xavier Morelli,Stéphane Betzi,Philippe Rocheet al. Organic & Biomolecular Chemistry, 2013, 11 (28), pp.4719-26. ⟨10.1039/c3ob40643a⟩ Article dans une revue hal-00871067v1
Synthesis of trifluoromethyl cyclohexyl, cyclohexenyl and aryl compounds via stepwise Robinson annulation Fabien Massicot,Alex Mor Iriarte,Thierry Brigaud,Aurélien Lebrun,Charles Portella Organic & Biomolecular Chemistry, 2011, 9 (2), pp.600-603. ⟨10.1039/c0ob00518e⟩ Article dans une revue hal-03561540v1
Photochemical electron transfer mediated addition of naphthylamine derivatives to electron deficient alkenes Rabih Jahjah,Abdoulaye Gassama,Frédéric Dumur,Sinisa Marinkovi C,Sabine Richertet al. Journal of Organic Chemistry, 2011, 76, pp.7104-7118. ⟨10.1021/jo201080m⟩ Article dans une revue hal-01020223v1

Poster de conférence (2)

Porphyrin Cages Assembled from N-heterocyclic Carbene-Metal Bonds Sébastien Richeter,Ludivine Poyac,Clémence Rose,Mohammad Wahiduzzaman,Aurélien Lebrunet al. International Symposium on Functional π-Electron Systems, Jun 2023, Raleigh (NC), United States Poster de conférence hal-04751522v1
Synthesis and Encapsulation Properties of Porphyrin Cages Assembled from N-heterocyclic Carbene-Metal Bonds Ludivine Poyac,Clémence Rose,Mohammad Wahiduzzaman,Aurélien Lebrun,Guillaume Cazalset al. International Conference on Porphyrins and Phthalocyanines 12, Madrid, Spain, 10-15 July 2022, Jul 2022, Madrid, Spain Poster de conférence hal-04762731v1

Pré-publication, Document de travail (1)

Fast and cost-efficient approaches for 17O-isotopic labeling of carboxylic groups in biomolecules: from free amino acids to peptide chains Jessica Špačková,Ieva Goldberga,Rishit Yadav,Guillaume Cazals,Aurélien Lebrunet al. 2022 Pré-publication, Document de travail (preprint/prepublication) hal-03846579v1