Aurélien LEBRUN Ingénieur d'Etudes Hors Classe en RMN

Identifiants chercheurs

IdHAL :

aurelien-lebrun

ORCID :

0000-0002-0801-9684

IdRef :

076433285

Présentation

Responsable d'un spectromètre RMN liquide 600 MHz équipé d'une cryoplateforme Prodigy avec cryosonde TCI.

Responsable de 2 spectromètres RMN liquide 400 MHz en libre accès.

Elucidation de structure de molécules organiques (substances naturelles, molécules issues de synthèse)

Publications

Article dans une revue (45)

Total Synthesis of Novel Oxylipins: Plasmodiophorols A, C, and Epimers Alexandre Guy,Aurélien Lebrun,Thierry Durand,Camille Oger European Journal of Organic Chemistry, In press, pp.e70449. ⟨10.1002/ejoc.70449⟩ Article dans une revue hal-05594772v1
French Propolis Caffeic Acid Derivatives Protect Skeletal Muscle from Oxidative Damages Luis Portillo-Lemus,Barbara Vernus,Béatrice Chabi,Aurélien Lebrun,Guillaume Cazalset al. Biomolecules, 2026, 16 (4), pp.550. ⟨10.3390/biom16040550⟩ Article dans une revue hal-05584320v1
Highly Flexible 3D Printed Gelatin-Pluronic F127 Scaffolds Seeded with Schwann Cells toward Nerve Regeneration Sacha Barberat,Sakthivel Nagarajan,Michel Habib,Aurélien Lebrun,Naomi Nieswicet al. ACS Biomaterials Science and Engineering, 2025, 11 (9), pp.5498-5511. ⟨10.1021/acsbiomaterials.5c00479⟩ Article dans une revue hal-05326766v1
Revisiting the Role of Intramolecular Proton Donation in ATC Foldamer Catalysts for Asymmetric Nitro-Michael Reactions Audrey Gacogne,Julie Aguesseau-Kondrotas,Samantha Chaise,Jean‐Marc Campagne,Aurélien Lebrunet al. Advanced Synthesis and Catalysis, 2025, pp.e70156. ⟨10.1002/adsc.70156⟩ Article dans une revue hal-05406145v1
From slag to structure: Formation of novel iron oxalate crystals via Cyrene™-driven microwave chemistry Limor Ben Neon,Aurelien Lebrun,Eddy Petit,Anne Julbe Materialia, 2025, 41, pp.102443. ⟨10.1016/j.mtla.2025.102443⟩ Article dans une revue hal-05090848v1
Catalyst Selection for Body-Temperature Curable Polyurethane Networks from Poly(δ-Decalactone) and Lysine Diisocyanate Marine Boursier,Aurelien Lebrun,Karine Parra,Sylvain Caillol,Julien Pinaudet al. Polymers, 2025, 17, pp.2548. ⟨10.3390/polym17182548⟩ Article dans une revue hal-05271415v1
Third‐Generation CD73 Inhibitors Based on a 4,6‐Disubstituted‐2‐Thiopyridine Scaffold Félix Grosjean,Maria Shaldaeva,Emeline Cros-Perrial,Céline Rodriguez,Rayane Ghoteimiet al. ChemMedChem, 2025, ⟨10.1002/cmdc.202400662⟩ Article dans une revue hal-04879866v1
Double Gyroid‐Forming Hybrid Anion Exchange Membranes With Superior Mechanical Properties Maximilien Coronas,Jason Richard,Eddy Petit,Aurélien Lebrun,Camille Bakkali Hassaniet al. Journal of Polymer Science, In press, ⟨10.1002/pol.20250675⟩ Article dans une revue hal-05356958v1
Selective acylation of chitosan oligomers by several cyclic anhydrides as a 13C NMR quantification method Paul Morandi,Steve Berthalon,Ghislain David,Aurelien Lebrun,Karine Parraet al. Carbohydrate Polymer Technologies and Applications, 2024, 7, pp.100498. ⟨10.1016/j.carpta.2024.100498⟩ Article dans une revue hal-04990543v1
One‐Pot Synthesis of Bioinspired Peptide‐Decorated Apatite Nanoparticles for Nanomedicine Mathilde Guerin,Aurélien Lebrun,Liisa Kuhn,Thierry Azaïs,Guillaume P. Laurentet al. Small, 2024, 20 (8), pp.2306358. ⟨10.1002/smll.202306358⟩ Article dans une revue hal-04295040v1
Star poly(lactide-co-glycolide) and poly(ε-caprolactone) polyurethanes with shape memory properties for biomedical applications Gaëlle Savin,Iliass Kadmiri,Sylvain Caillol,Philippe Gonzalez,Aurélien Lebrunet al. European Polymer Journal, 2024, 220, pp.113442. ⟨10.1016/j.eurpolymj.2024.113442⟩ Article dans une revue hal-04699510v1
Fast and Cost‐Efficient 17 O‐Isotopic Labeling of Carboxylic Groups in Biomolecules: From Free Amino Acids to Peptide Chains Jessica Špačková,Ieva Goldberga,Rishit Yadav,Guillaume Cazals,Aurélien Lebrunet al. Chemistry - A European Journal, 2023, 29 (10), pp.e202203014. ⟨10.1002/chem.202203014⟩ Article dans une revue hal-04002744v1
Paving the Way towards Sustainability of Polyurethanes: Synthesis and Properties of Terpene-Based Diisocyanate Aliénor Delavarde,Sebastien Lemouzy,Aurélien Lebrun,Julien Pinaud,Sylvain Caillol Molecules, 2023, 28 (20), pp.7133. ⟨10.3390/molecules28207133⟩ Article dans une revue hal-04246489v1
Mapping the N-Terminal Hexokinase-I Binding Site onto Voltage-Dependent Anion Channel-1 To Block Peripheral Nerve Demyelination Benoit Gautier,Mélanie Forêt Jacquard,Sophie Guelfi,Scarlette Abbou,Elisa Gonzalezet al. Journal of Medicinal Chemistry, 2022, 65 (17), pp.11633-11647. ⟨10.1021/acs.jmedchem.2c00411⟩ Article dans une revue hal-03987562v1
Fluorescent Dynamic Covalent Polymers for DNA Complexation and Templated Assembly Clément Kotras,Maxime Leclercq,Maxime Roger,Camille Bouillon,Antonio Recupidoet al. Molecules, 2022, 27 (19), pp.6648. ⟨10.3390/molecules27196648⟩ Article dans une revue hal-03832051v1
Vegetable oil-based hybrid microparticles as a green and biocompatible system for subcutaneous drug delivery Koceïla Doufène,Ilaria Basile,Aurélien Lebrun,Nelly Pirot,Aurélie Escandeet al. International Journal of Pharmaceutics, 2021, 592, pp.120070. ⟨10.1016/j.ijpharm.2020.120070⟩ Article dans une revue hal-03110144v1
Cost-efficient and user-friendly 17O/ 18O labeling procedures of fatty acids using mechanochemistry Jessica Špačková,Charlyn Fabra,Guillaume Cazals,Marie Hubert-Roux,Isabelle Schmitz-Afonsoet al. Chemical Communications, 2021, 57 (55), pp.6812-6815. ⟨10.1039/D1CC02165F⟩ Article dans une revue hal-03322217v1
A Novel Sesquiterpene Lactone Xanthatin-13-(pyrrolidine-2-carboxylic acid) Isolated from Burdock Leaf Up-Regulates Cells’ Oxidative Stress Defense Pathway Yanis A Idres,Didier Tousch,Guillaume Cazals,Aurélien Lebrun,Sarah Naceriet al. Antioxidants , 2021, 10 (10), ⟨10.3390/antiox10101617⟩ Article dans une revue hal-03434251v1
Synthesis, Characterization and Encapsulation Properties of Rigid and Flexible Porphyrin Cages Assembled from N-Heterocyclic Carbene-Metal Bonds Ludivine Poyac,Clémence Rose,Mohammad Wahiduzzaman,Aurélien Lebrun,Guillaume Cazalset al. Inorganic Chemistry, 2021, 60 (24), pp.19009-19021. ⟨10.1021/acs.inorgchem.1c02868⟩ Article dans une revue hal-03518954v1
Unveiling the Structure and Reactivity of Fatty-Acid Based (Nano)materials Thanks to Efficient and Scalable 17O and 18O-Isotopic Labeling Schemes Jessica Špačková,Charlyn Fabra,Sébastien Mittelette,Emeline Gaillard,Chia-Hsin Chenet al. Journal of the American Chemical Society, 2020, 142 (50), pp.21068-21081. ⟨10.1021/jacs.0c09383⟩ Article dans une revue hal-03117231v1
Inorganic Sol−Gel Polymerization for Hydrogel Bioprinting Titouan Montheil,Marie Maumus,Laurine Valot,Aurélien Lebrun,Jean Martínezet al. ACS Omega, 2020, 5 (6), pp.2640-2647. ⟨10.1021/acsomega.9b03100⟩ Article dans une revue hal-02513894v1
Molecular complexes and main-chain organometallic polymers based on Janus bis(carbenes) fused to metalloporphyrins Jean-François Longevial,Mamadou Lo,Aurélien Lebrun,Danielle Laurencin,Sébastien Clémentet al. Dalton Transactions, In press, 49, pp.7005-7014. ⟨10.1039/D0DT00594K⟩ Article dans une revue hal-02568903v1
DNA‐Based Asymmetric Inverse Electron‐Demand Hetero‐Diels–Alder Justine Mansot,Jimmy Lauberteaux,Aurélien Lebrun,Marc Mauduit,Jean-Jacques Vasseuret al. Chemistry - A European Journal, 2020, 26 (16), pp.3519-3523. ⟨10.1002/chem.202000516⟩ Article dans une revue hal-02512892v1
Iron-Catalyzed Enantioselective Intramolecular Inverse Electron-Demand Hetero Diels–Alder Reactions: An Access to Bicyclic Dihydropyran Derivatives Jimmy Lauberteaux,Aurélien Lebrun,Arie van Der Lee,Marc Mauduit,Renata Marcia de Figueiredoet al. Organic Letters, 2019, 21 (24), pp.10007-10012. ⟨10.1021/acs.orglett.9b03752⟩ Article dans une revue hal-02429682v1
A multinuclear NMR perspective on the complexation between bisboronic acids and bisbenzoxaboroles with cis -diols Adèle Larcher,Aurélien Lebrun,Michael Smietana,Danielle Laurencin New Journal of Chemistry, 2018, 42 (4), pp.2815 - 2823. ⟨10.1039/C7NJ04143H⟩ Article dans une revue hal-01708542v1
Fused Bis-lactams to Spirolactams: A New Member of the Family of Ring- Contraction Reaction Guilhem Chaubet,Mathéo Berthet,Morgane Pasco,Guillaume Cazals,Aurelien Lebrunet al. Letters in Organic Chemistry, 2018, 15 (12), pp.1046-1055. ⟨10.2174/1570178615666180326160131⟩ Article dans une revue hal-02388789v1
Vinyl-aziridines and cyclopropanes in Pd-catalyzed (3+2)-cycloaddition reactions with cyclic N-sulfonyl imines Kim Spielmann,Eleonora Tosi,Aurélien Lebrun,Gilles Niel,Arie van Der Leeet al. Tetrahedron, 2018, 74 (45), pp.6497 - 6511. ⟨10.1016/j.tet.2018.09.040⟩ Article dans une revue hal-01892430v1
Cofacial porphyrin dimers assembled from N-heterocyclic carbene–metal bonds Clémence Rose,Aurélien Lebrun,Sébastien Clément,Sébastien Richeter Chemical Communications, 2018, 54 (69), pp.9603 - 9606. ⟨10.1039/C8CC05707A⟩ Article dans une revue hal-01862544v1
Hydrophobic alpha,alpha-Disubstituted Disilylated TESDpg Induces Incipient 3 10 -Helix in Short Tripeptide Sequence Roberto Fanelli,Dorothée Berthomieu,Claude Didierjean,Abdelatif Doudouh,Aurélien Lebrunet al. Organic Letters, 2017, 19 (11), pp.2937 - 2940. ⟨10.1021/acs.orglett.7b01172⟩ Article dans une revue hal-01552320v1
Porphyrins Conjugated with Peripheral Thiolato Gold(I) Complexes for Enhanced Photodynamic Therapy Jean-François Longevial,Khaled El cheikh,Dina Aggad,Aurélien Lebrun,Arie Van der leeet al. Chemistry - A European Journal, 2017, 23, pp.14017-14026. ⟨10.1002/chem.201702975⟩ Article dans une revue hal-01613027v1
Oxa-diketopiperazines: Access and Conformational Analysis of Potential Turn Inducers Mathéo Berthet,Aurélien Lebrun,Arnaud Martel,Thomas Cheviet,Jean Martinezet al. ChemistrySelect, 2017, 2 (21), pp.5824-5827. ⟨10.1002/slct.201701393⟩ Article dans une revue hal-02313808v1
Selective homodimerization of unprotected peptides using hybrid hydroxydimethylsilane derivatives Cécile Echalier,Alexandra Kalistratova,Jeremie Ciccione,Aurelien Lebrun,Baptiste Legrandet al. RSC Advances, 2016, ⟨10.1039/c6ra06075g⟩ Article dans une revue hal-01345976v1
Synthesis under moderate pressure of 3-imidazo[1,2- a ]pyridinylidene pyrrol-2-ones Nicolas Masurier,Aurélien Lebrun,Damien Canitrot,Jean-Michel Chezal,Emmanuel Moreau Tetrahedron Letters, 2016, 57 (24), pp.2583-2586. ⟨10.1016/j.tetlet.2016.04.093⟩ Article dans une revue istex hal-03564389v1
A Catalytically Competent Terpene Synthase Inferred Using Ancestral Sequence Reconstruction Strategy Daniele Guzzetti,Aurelien Lebrun,Maeva Subileau,Estelle Grousseau,Eric Dubreucqet al. ACS Catalysis, 2016, 6 (8), pp.5345 - 5349. ⟨10.1021/acscatal.6b01332⟩ Article dans une revue hal-01506512v1
N-Pyrrolidine-based alpha/beta-peptides incorporating ABOC, a constrained bicyclic beta-amino acid, for asymmetric aldol reaction catalysis Pierre Milbeo,Kelly Maurent,Laure Moulat,Aurelien Lebrun,Claude Didierjeanet al. Tetrahedron, 2016, 72 (13), pp.1706-1715. ⟨10.1016/j.tet.2016.02.027⟩ Article dans une revue hal-01532027v1
Selenazolidine: a selenium containing proline surrogate in peptide science E. Cordeau,S. Cantel,D. Gagne,A. Lebrun,J. Martinezet al. Organic & Biomolecular Chemistry, 2016, 14 (34), pp.8101-8108. ⟨10.1039/C6OB01450J⟩ Article dans une revue hal-03564292v1
Straightforward synthesis towards mono and bis-phosphonic acid functionalised β-cyclodextrins April Marquick,Jean-Louis Montero,Aurélien Lebrun,Véronique Barragan-Montero Tetrahedron, 2015, 71 (10), pp.1616-1621. ⟨10.1016/j.tet.2014.12.019⟩ Article dans une revue hal-03592418v1
Synthesis and structural characterization of monomeric and dimeric peptide nucleic acids prepared by using microwave-promoted multicomponent reactions Reuben Ovadia,Aurelien Lebrun,Ivan Barvik,Jean-Jacques Vasseur,Carine Baragueyet al. Organic & Biomolecular Chemistry, 2015, 13, pp.11052-11071. ⟨10.1039/c5ob01604e⟩ Article dans une revue hal-01438999v1
Silaproline Helical Mimetics Selectively Form an All-trans PPII Helix Charlotte Martin,Baptiste Legrand,Aurélien Lebrun,Dorothée Berthomieu,Jean Martinezet al. Chemistry - A European Journal, 2014, 20 (44), pp.1420-14244. ⟨10.1002/chem.201404820⟩ Article dans une revue istex hal-01078148v1
From Diketopiperazines to Hydantoins: An Unprecedented Rearrangement Guilhem Chaubet,Guillaume Cazals,Aurélien Lebrun,Jean Martinez,Isabelle Parrot SYNLETT, 2014, 25 (4), pp.574-578. ⟨10.1055/s-0033-1340622⟩ Article dans une revue hal-00951723v1
Thiazole-Based γ-Building Blocks as Reverse-Turn Mimetic to Design a Gramicidin S Analogue: Conformational and Biological Evaluation Baptiste Legrand,Loic Mathieu,Aurélien Lebrun,Soahary Andriamanarivo,Vincent Lisowskiet al. Chemistry - A European Journal, 2014, 20 (22), pp.6713-6720. ⟨10.1002/chem.201402190⟩ Article dans une revue istex hal-02912610v1
Synthesis of Homopolypeptides with PPII Structure Charlotte Martin,Aurélien Lebrun,Jean Martinez,Florine Cavelier Journal of Polymer Science, 2013, 51, pp.3103-3109. ⟨10.1002/pola.26705⟩ Article dans une revue istex hal-00838581v1
Stereoselective synthesis of original spirolactams displaying promising folded structures. Guilhem Chaubet,Thibault Coursindel,Xavier Morelli,Stéphane Betzi,Philippe Rocheet al. Organic & Biomolecular Chemistry, 2013, 11 (28), pp.4719-26. ⟨10.1039/c3ob40643a⟩ Article dans une revue hal-00871067v1
Synthesis of trifluoromethyl cyclohexyl, cyclohexenyl and aryl compounds via stepwise Robinson annulation Fabien Massicot,Alex Mor Iriarte,Thierry Brigaud,Aurélien Lebrun,Charles Portella Organic & Biomolecular Chemistry, 2011, 9 (2), pp.600-603. ⟨10.1039/c0ob00518e⟩ Article dans une revue hal-03561540v1
Photochemical electron transfer mediated addition of naphthylamine derivatives to electron deficient alkenes Rabih Jahjah,Abdoulaye Gassama,Frédéric Dumur,Sinisa Marinkovi C,Sabine Richertet al. Journal of Organic Chemistry, 2011, 76, pp.7104-7118. ⟨10.1021/jo201080m⟩ Article dans une revue hal-01020223v1

Poster de conférence (2)

Porphyrin Cages Assembled from N-heterocyclic Carbene-Metal Bonds Sébastien Richeter,Ludivine Poyac,Clémence Rose,Mohammad Wahiduzzaman,Aurélien Lebrunet al. International Symposium on Functional π-Electron Systems, Jun 2023, Raleigh (NC), United States Poster de conférence hal-04751522v1
Synthesis and Encapsulation Properties of Porphyrin Cages Assembled from N-heterocyclic Carbene-Metal Bonds Ludivine Poyac,Clémence Rose,Mohammad Wahiduzzaman,Aurélien Lebrun,Guillaume Cazalset al. International Conference on Porphyrins and Phthalocyanines 12, Madrid, Spain, 10-15 July 2022, Jul 2022, Madrid, Spain Poster de conférence hal-04762731v1

Pré-publication, Document de travail (1)

Fast and cost-efficient approaches for 17O-isotopic labeling of carboxylic groups in biomolecules: from free amino acids to peptide chains Jessica Špačková,Ieva Goldberga,Rishit Yadav,Guillaume Cazals,Aurélien Lebrunet al. 2022 Pré-publication, Document de travail (preprint/prepublication) hal-03846579v1