Badreddine Douzi Badreddine Douzi

Identifiants chercheurs

IdHAL :

badreddine-douzi

ORCID :

0000-0003-3140-4713

IdRef :

159182816

Présentation

Publications

Article dans une revue (42)

Co-option of an ancestral peptidase controls developmental patterning in multicellular cyanobacteria Xiaomei Xu,Anaïs Scholivet,Stéphanie Champ,Matthieu Bergé,Zulihumaer Yeerkenjianget al. iScience, 2026, 29 (1), pp.114265. ⟨10.1016/j.isci.2025.114265⟩ Article dans une revue hal-05457710v1
Elucidating assembly and function of VirB8 cell wall subunits refines the DNA translocation model in Gram-positive T4SSs Robine Maffo-Woulefack,Abbas Mohamad Ali,Haifa Laroussi,Julien Cappele,Felipe Romero-Saavedraet al. Science Advances , 2025, 11 (4), pp.eadq5975. ⟨10.1126/sciadv.adq5975⟩ Article dans une revue hal-04916057v1
Massive acquisition of conjugative and mobilizable integrated elements fuels Faecalibacterium plasticity and hints at their adaptation to the gut Gérard Guédon,Florence Charron-Bourgoin,Thomas Lacroix,Toufik Hamadouche,Nicolas Soleret al. Scientific Reports, 2025, 15 (1), pp.17013. ⟨10.1038/s41598-025-99981-y⟩ Article dans une revue hal-05397378v1
Two OB-fold proteins from a Gram-positive conjugative element engage in relaxosome assembly and DNA processing Haifa Laroussi,Robine Maffo-Woulefack,Julien Cappèle,Hicham Sekkouri Alaoui,Lysiane Lessureet al. Nucleic Acids Research, 2025, 53 (21), pp.gkaf1161. ⟨10.1093/nar/gkaf1161⟩ Article dans une revue hal-05445247v1
Unravelling HetC as a peptidase-based ABC exporter driving functional cell differentiation in the cyanobacterium Nostoc PCC 7120 Raphaël Rachedi,Véronique Risoul,Maryline Foglino,Yanis Aoudache,Kevin Langet al. Microbiology Spectrum, 2024, 12 (4), ⟨10.1128/spectrum.04058-23⟩ Article dans une revue hal-04539483v1
Refining the Dynamic Network of T2SS Endopilus Tip Heterocomplex Combining cw‐EPR and Nitroxide–Gd III Distance Measurements Guillaume Gerbaud,Brice Barbat,Mathilde Tribout,Emilien Etienne,Valérie Belleet al. ChemBioChem, 2023, 24 (15), ⟨10.1002/cbic.202300099⟩ Article dans une revue hal-04210232v1
Insights into dynamics and gating properties of T2SS secretins Brice Barbat,Badreddine Douzi,Geneviève Ball,Mathilde Tribout,Khalid El Karkouriet al. Science Advances , 2023, 9 (40), ⟨10.1126/sciadv.adg6996⟩ Article dans une revue hal-04254401v1
A new twin expands the VirB8-like protein family Robine Maffo-Woulefack,Nathalie N. Leblond-Bourget,Badreddine Douzi Structure, 2022, 30 (6), pp.790-792. ⟨10.1016/j.str.2022.05.004⟩ Article dans une revue hal-03994713v1
The crystal structure of CbpD clarifies substrate-specificity motifs in chitin-active lytic polysaccharide monooxygenases Christopher Dade,Badreddine Douzi,Christian Cambillau,Genevieve Ball,Romé Voulhouxet al. Acta crystallographica Section D : Structural biology [1993-..], 2022, 78 (8), pp.1064-1078. ⟨10.1107/S2059798322007033⟩ Article dans une revue hal-03739502v1
Structural lessons on bacterial secretins Brice Barbat,Badreddine Douzi,Romé Voulhoux Biochimie, 2022, 205, pp.110-116. ⟨10.1016/j.biochi.2022.08.019⟩ Article dans une revue hal-03845257v1
Exploration of DNA processing features unravels novel properties of ICE conjugation in Gram-positive bacteria Haifa Laroussi,Yanis Aoudache,Emilie Robert,Virginie Libante,Louise Thirietet al. Nucleic Acids Research, 2022, 50 (14), pp.8127-8142. ⟨10.1093/nar/gkac607⟩ Article dans une revue hal-03881644v1
Structural and Biochemical Analysis of OrfG: The VirB8-like Component of the Conjugative Type IV Secretion System of ICESt3 From Streptococcus thermophilus Julien Cappele,Abbas Mohamad Ali,Nathalie N. Leblond-Bourget,Sandrine Mathiot,Tiphaine Dhalleineet al. Frontiers in Molecular Biosciences, 2021, 8, ⟨10.3389/fmolb.2021.642606⟩ Article dans une revue hal-03196531v1
Structural interactions define assembly adapter function of a type II secretion system pseudopilin Cristian Escobar,Badreddine Douzi,Geneviève Ball,Brice Barbat,Sebastien Alphonseet al. Structure, 2021, 29 (10), pp.1116-1127.e8. ⟨10.1016/j.str.2021.05.015⟩ Article dans une revue hal-03367306v1
HetL, HetR and PatS form a reaction-diffusion system to control pattern formation in the cyanobacterium Nostoc PCC 7120 Xiaomei Xu,Véronique Risoul,Deborah Byrne,Stéphanie M Champ,Badreddine Douziet al. eLife, 2020, 9, ⟨10.7554/eLife.59190⟩ Article dans une revue hal-02917356v1
YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli Elsa Germain,Paul Guiraud,Deborah Byrne,Badreddine Douzi,Meriem Djendliet al. Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-13764-4⟩ Article dans une revue hal-02446175v1
Structure–Function Analysis of the C-Terminal Domain of the Type VI Secretion TssB Tail Sheath Subunit Badreddine Douzi,Laureen Logger,Silvia Spinelli,Stephanie Blangy,Christian Cambillauet al. Journal of Molecular Biology, 2018, 430 (3), pp.297 - 309. ⟨10.1016/j.jmb.2017.11.015⟩ Article dans une revue hal-01780748v1
The gp27-like Hub of VgrG Serves as Adaptor to Promote Hcp Tube Assembly Melvin G Renault,Jordi Zamarreño Beas,Badreddine Douzi,Maïalène Chabalier,Abdelrahim Zouedet al. Journal of Molecular Biology, 2018, 430 (18 Pt B), pp.3143-3156. ⟨10.1016/j.jmb.2018.07.018⟩ Article dans une revue hal-01847145v1
Towards a complete structural deciphering of Type VI secretion system van Son Nguyen,Badreddine Douzi,Eric Durand,Alain Roussel,E. Cascaleset al. Current Opinion in Structural Biology, 2018, 49, pp.77 - 84. ⟨10.1016/j.sbi.2018.01.007⟩ Article dans une revue hal-01780753v1
Direct interactions between the secreted effector and the T2SS components GspL and GspM reveal a new effector-sensing step during type 2 secretion Sandra Michel-Souzy,Badreddine Douzi,Frederic Cadoret,Claire Raynaud,Loïc Quintonet al. Journal of Biological Chemistry, 2018, 293 (50), pp.19441-19450. ⟨10.1074/jbc.RA117.001127⟩ Article dans une revue hal-01919531v1
Unraveling the Self-Assembly of the Pseudomonas aeruginosa XcpQ Secretin Periplasmic Domain Provides New Molecular Insights into Type II Secretion System Secreton Architecture and Dynamics Badreddine Douzi,Nhung Trinh,Sandra Michel-Souzy,Aline Desmyter,Genevieve Ballet al. mBio, 2017, 8 (5), ⟨10.1128/mBio.01185-17⟩ Article dans une revue hal-01744494v1
Structure–Function Analysis of the TssL Cytoplasmic Domain Reveals a New Interaction between the Type VI Secretion Baseplate and Membrane Complexes Abdelrahim Zoued,Chloé J Cassaro,Eric Durand,Badreddine Douzi,Alexandre Españaet al. Journal of Molecular Biology, 2016, 428 (22), pp.4413 - 4423. ⟨10.1016/j.jmb.2016.08.030⟩ Article dans une revue hal-01780163v1
Structure and specificity of the Type VI secretion system ClpV-TssC interaction in enteroaggregative Escherichia coli Badreddine Douzi,Yannick R Brunet,Silvia Spinelli,Valentine Lensi,Stephanie Blangyet al. Scientific Reports, 2016, 6 (1), ⟨10.1038/srep34405⟩ Article dans une revue hal-01780690v1
Priming and polymerization of a bacterial contractile tail structure. 1&quot; 2&quot; 17 Abdelrahim Zoued,Eric Durand,Yannick R Brunet,Silvia Spinelli,Badreddine Douziet al. Nature, 2016, 531 (7592), pp.59 - 63. ⟨10.1038/nature17182⟩ Article dans une revue hal-01778575v1
The Type VI Secretion TssEFGK-VgrG Phage-Like Baseplate Is Recruited to the TssJLM Membrane Complex via Multiple Contacts and Serves As Assembly Platform for Tail Tube/Sheath Polymerization Yannick R Brunet,Abdelrahim Zoued,Frédéric Boyer,Badreddine Douzi,E. Cascales PLoS Genetics, 2015, 11 (10), pp.e1005545. ⟨10.1371/journal.pgen.1005545⟩ Article dans une revue hal-01458191v1
Inhibition of Type VI Secretion by an Anti-TssM Llama Nanobody van Son Nguyen,Laureen Logger,Silvia Spinelli,Aline Desmyter,Thi Thu Hang Leet al. PLoS ONE, 2015, 10 (e0122187), pp.1-14 Article dans une revue hal-01217205v1
Architecture and assembly of the Type VI secretion system. Abdelrahim Zoued,Yannick R Brunet,Eric Durand,Marie-Stéphanie Aschtgen,Laureen Loggeret al. Biochim. Biophys. Acta, 2014, 1843 (8), pp.1664--73. ⟨10.1016/j.bbamcr.2014.03.018⟩ Article dans une revue hal-01458220v1
Crystal Structure and Self-Interaction of the Type VI Secretion Tail-Tube Protein from Enteroaggregative Escherichia coli Badreddine Douzi,Silvia Spinelli,Stéphanie Blangy,Alain Roussel,Eric Durandet al. PLoS ONE, 2014, 9 (2), pp.e86918. ⟨10.1371/journal.pone.0086918⟩ Article dans une revue hal-02091448v1
Txc, a new type II secretion system of Pseudomonas aeruginosa strain PA7, is regulated by the TtsS/TtsR two-component system and directs specific secretion of the CbpE chitin-binding protein. Frederic Cadoret,Geneviève Ball,Badreddine Douzi,Romé Voulhoux Journal of Bacteriology, 2014, 196 (13), pp.2376--86. ⟨10.1128/JB.01563-14⟩ Article dans une revue hal-01458218v1
Crystal Structure and Self-Interaction of the Type VI Secretion Tail-Tube Protein from Enteroaggregative Escherichia coli Badreddine Douzi,Silvia Spinelli,Stéphanie Blangy,Alain Roussel,Eric Durandet al. PLoS ONE, 2014, 9 (2), pp.e86918. ⟨10.1371/journal.pone.0086918⟩ Article dans une revue hal-03274780v1
Architecture and assembly of the Type VI secretion system Abdelrahim Zoued,Yannick Brunet,Eric Durand,Marie-Stéphanie Aschtgen,Laureen Loggeret al. Biochimica et Biophysica Acta - Molecular Cell Research, 2014, 1843 (8), pp.1664-1673. ⟨10.1016/j.bbamcr.2014.03.018⟩ Article dans une revue hal-03274779v1
TssK Is a Trimeric Cytoplasmic Protein Interacting with Components of Both Phage-like and Membrane Anchoring Complexes of the Type VI Secretion System Abdelrahim Zoued,Eric Durand,Cecilia C. Bebeacua,Yannick R Brunet,Badreddine Douziet al. Journal of Biological Chemistry, 2013, 288 (38), pp.27031-27041. ⟨10.1074/jbc.M113.499772⟩ Article dans une revue hal-02091435v1
Dissection of the TssB-TssC Interface during Type VI Secretion Sheath Complex Formation Xiang Y. Zhang,Yannick R Brunet,Laureen Logger,Badreddine Douzi,Christian Cambillauet al. PLoS ONE, 2013, 8 (11), pp.e81074. ⟨10.1371/journal.pone.0081074⟩ Article dans une revue hal-02091436v1
High throughput screening identifies disulfide isomerase DsbC as a very efficient partner for recombinant expression of small disulfide-rich proteins in E. coli Hervé Nozach,Carole Fruchart-Gaillard,François Fenaille,Fabrice Beau,Oscar Pereira Ramoset al. Microbial Cell Factories, 2013, 12, ⟨10.1186/1475-2859-12-37⟩ Article dans une revue cea-02100032v1
On the path to uncover the bacterial type II secretion system. Badreddine Douzi,Alain Filloux,Romé Voulhoux Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2012, 367 (1592), pp.1059--72. ⟨10.1098/rstb.2011.0204⟩ Article dans une revue hal-01458255v1
Towards a structural comprehension of bacterial type VI secretion systems: characterization of the TssJ-TssM complex of an Escherichia coli pathovar Catarina Felisberto-Rodrigues,Eric Durand,Marie-Stéphanie Aschtgen,Stephanie Blangy,Miguel Ortiz-Lombardiaet al. PLoS Pathogens, 2011, 7 (11), pp.e1002386. ⟨10.1371/journal.ppat.1002386⟩ Article dans une revue hal-01458272v1
Structure of the minor pseudopilin XcpW from the Pseudomonas aeruginosa type II secretion system. Laura P Franz,Badreddine Douzi,Eric Durand,David H Dyer,Romé Voulhouxet al. Acta Crystallogr. D Biol. Crystallogr., 2011, 67 (Pt 2), pp.124--30. ⟨10.1107/S0907444910051954⟩ Article dans une revue hal-01458266v1
Deciphering the Xcp Pseudomonas aeruginosa type II secretion machinery through multiple interactions with substrates. Badreddine Douzi,Geneviève Ball,Christian Cambillau,Mariella Tegoni,Romé Voulhoux Journal of Biological Chemistry, 2011, 286 (47), pp.40792--801. ⟨10.1074/jbc.M111.294843⟩ Article dans une revue hal-01458270v1
Towards a Structural Comprehension of Bacterial Type VI Secretion Systems: Characterization of the TssJ-TssM Complex of an Escherichia coli Pathovar Catarina Felisberto-Rodrigues,Eric Durand,Marie-Stéphanie Aschtgen,Stéphanie Blangy,Miguel Ortiz-Lombardiaet al. PLoS Pathogens, 2011, 7 (11), pp.e1002386. ⟨10.1371/journal.ppat.1002386⟩ Article dans une revue hal-03274802v1
The Assembly Mode of the Pseudopilus: a hallmark to distinguish a novel secretion system subtype E. Durand,S. Alphonse,Céline Brochier-Armanet,G. Ball,Badreddine Douziet al. Journal of Biological Chemistry, 2011, 286 (27), pp.24407-24416. ⟨10.1074/jbc.M111.234278⟩ Article dans une revue hal-02299276v1
D-Maurocalcine, a pharmacologically inert efficient cell-penetrating peptide analogue. Cathy Poillot,Kaouthar Dridi,Hicham Bichraoui,Julien Pêcher,Sébastien Alphonseet al. Journal of Biological Chemistry, 2010, 285 (44), pp.34168-80. ⟨10.1074/jbc.M110.104919⟩ Article dans une revue inserm-00587800v1
Structure of the Pseudomonas aeruginosa XcpT pseudopilin, a major component of the type II secretion system S. Alphonse,E. Durand,Badreddine Douzi,B. Waegele,H. Darbonet al. Journal of Structural Biology, 2010, 169 (1), pp.75-80. ⟨10.1016/j.jsb.2009.09.003⟩ Article dans une revue hal-02667520v1
The XcpV/GspI pseudopilin has a central role in the assembly of a quaternary complex within the T2SS pseudopilus Badreddine Douzi,E. Durand,C. Bernard,S. Alphonse,C. Cambillauet al. Journal of Biological Chemistry, 2009, 284 (50), pp.34580-34589. ⟨10.1074/jbc.M109.042366⟩ Article dans une revue hal-02666049v1

Communication dans un congrès (4)

Structural and Biochemical Analysis of OrfG: The VirB8-like Component of the Conjugative Type IV Secretion System of ICESt3 From Streptococcus thermophilus Julien Cappele,Badreddine Douzi,Abbas Mohamad Ali,Nathalie Leblond-Bourget,Sandrine Mathiotet al. SFB-GEM Meeting 2021 - Biophysics of membranes and beyond., Sep 2021, Online, France Communication dans un congrès hal-03576846v1
Nanobodies to investigate the architecture and dynamics of the Type II secretion nanomachine Badreddine Douzi Third FRISBI annual user meeting, Nov 2017, paris, France Communication dans un congrès hal-02791428v1
Nanobodies uncover a new transport pathway of the secretin XcpQ to the outer membrane Badreddine Douzi JSM3 Junior Scientist Microbiology, May 2016, marseille, France Communication dans un congrès hal-02744297v1
Deciphering the Type II secretion system dynamics and function Badreddine Douzi EMBO-Clostridial Secretion, Sep 2012, marseille, France Communication dans un congrès hal-02750355v1

Poster de conférence (5)

Deciphering the structural organization of OrfG, the VirB8-like of ICESt3 Type IV secretion system (T4SS) Badreddine Douzi FEBS2023, Jul 2023, Tours, France Poster de conférence hal-04223319v1
Self-assembly of XcpQ secretin N domain into hexamer of dimers provides new molecular insights into architecture and dynamics of widespread outer membrane channels Badreddine Douzi,Romé Voulhoux,- Nhung. T. T. Trinh,- Sandra Michel-Souzy,Aline Desmyteret al. New Approaches and Concepts in Microbiology, Jun 2017, Heidelberg, Germany. , 2017 Poster de conférence hal-02737898v1
Minor pseudopilins of the type II secretion system in P. aeruginosa: placing pieces in a large puzzle Badreddine Douzi,Romé Voulhoux,Eric Durand,Loïc Quinton,Edwin de Pauwet al. ASM Conference on Pseudomonas 2015, Sep 2015, Washington, United States. , 2015 Poster de conférence hal-02743889v1
Towards a better understanding of the bacterial type II secretion pathway Badreddine Douzi,- Sandra Michel,Frédéric Cadoret,Geneviève Ball,Bérengère Izeet al. SGM ANNUAL CONFERENCE, Apr 2014, Liverpool, United Kingdom. , 2014 Poster de conférence hal-02744249v1
The XcpV/GspI pseudopilin has a central role in the assembly of a quaternary complex within the T2SS pseudopilus Badreddine Douzi,Sébastien Alphonse,Herve Darbon,Alain Filloux,Christian Cambillauet al. Colloque de l'école doctorale Aix-Marseille, Jun 2009, Marseille, France. 1p, 2009 Poster de conférence hal-02824819v1

Chapitre d'ouvrage (1)

Protein-Protein Interactions: Surface Plasmon Resonance Badreddine Douzi Bacterial Protein Secretion Systems : Methods and Protocols, Springer Link, 2017, Methods in Molecular Biology, 978-1-4939-7033-9 978-1-4939-7031-5. ⟨10.1007/978-1-4939-7033-9_21⟩ Chapitre d'ouvrage hal-02790765v1

Thèse (1)

La machinerie de sécrétion de type II Xcp de pseudomonas aeruginosa Badreddine Douzi Sciences du Vivant [q-bio]. Université de Provence, 2011. Français. ⟨NNT : ⟩ Thèse tel-02806009v1

Rapport (1)

Assessment of Research and Innovation on Food Systems by European member States Badreddine Douzi [0] Ruropean Commision. 2018 Rapport (rapport d’expertise collective) hal-02947601v1

Vidéo (2)

Laboratoire Dynamic . Une collaboration avec le CRM2, laboratoire de Cristallographie, Résonance Magnétique et Modélisations Claude Didierjean,Badreddine Douzi 2020 Vidéo hal-03367957v1
Limiter l'antibiorésistance, un enjeu du 21e siècle Badreddine Douzi,Sophie Payot,Nicolas Soler 2020 Vidéo hal-03228358v1