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Characterization of a new Post Translational Modification of Neurofibromin: atypical structural requirements for its SUMOylation
Mohammed Bergoug
,
Christine Mosrin-Huaman
,
Amandine Serrano
,
Fabienne Godin
,
Michel Doudeau
2024 Global NF Conference, Jun 2024, Brussels, Belgium
Conference poster
hal-03679991v1
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Deciphering the Molecular Mechanism of Pathogenicity in Destabilized variants of Neurofibromin mutated in its SecPH domain
Hélène Bénédetti
,
Christine Mosrin-Huaman
,
Mohammed Bergoug
,
Amandine Serrano
,
Fabienne Godin
2024 Global NF Conference, Jun 2024, Brussels (Belgium), Belgium
Conference poster
hal-04779581v1
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Stressed by hydrogel? Physiological response of yeast cells embedded in thermoresponsive Pluronic F127: a prerequisite for bioreactor development
Bojan Zunar
,
Christine Mosrin-Huaman
,
Hélène Bénédetti
,
Régis Guégan
,
Béatrice Vallée
FEBS 2021, the 45th FEBS Congress, Jul 2021, Ljubljana, Slovenia
Conference poster
hal-03679975v1
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Development of a bioactive fluorescent inhibitor probe targeting the Rho kinase ROCK for monitoring inhibition action
Justine Corret
,
Sokaina Hammoud
,
Frédéric Buron
,
Pierre Daligaux
,
Christophe Chesné
FEBS 2021, the 45th FEBS Congress, Jul 2021, Lnubljana, virtual, Slovenia
Conference poster
hal-03679980v1
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New molecular insights into the crosstalk between Rho/ROCK/LIMK2/cofilin signalling pathway and Nf1
Mélissa Thomas
,
Lauren Blot
,
Kevin Lesage
,
Fabienne Godin
,
Michel Doudeau
2021 NF1 virtual conference, Jun 2021, Virtual, France
Conference poster
hal-03679999v1
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New insights into the regulation of actin cytoskeleton dynamics via the Rho/ROCK/LIMK2/cofilin signalling pathway: a novel mechanism of regulation of cofilin by LIMK2
Elodie Villalonga
,
Célina Chalal
,
Déborah Cassas
,
Michel Doudeau
,
Fabienne Godin
FEBS 2021, the 45th FEBS Congress, Jul 2021, Ljubljana, virtual, Slovenia
Conference poster
hal-03680139v1
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High Efficiency of Histidylated-based Lipid Formulations for mRNA Transfection of Human Schwann Cells
N Laroui
,
C Delehedde
,
Cristine Gonçalves
,
F Godin
,
F Perche
10th mRNA Health Conference, Nov 2021, Berlin, Germany
Conference poster
hal-03668434v1
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Sumoylation of Neurofibromin and its SecPH Domain Plays a Role in Their Functions and Implies Unexpected Structural Requirements
Christine Mosrin-Huaman
,
Mohammed Bergoug
,
Fabienne Godin
,
Michel Doudeau
,
Iva Sosic
2021 NF1 virtual conference, Jun 2021, Virtual, France
Conference poster
hal-03680001v1
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LIM kinases, new therapeutic targets to treat cancers, neurological disorders and Neurofibromatosis: development of small molecule inhibitors
Béatrice Vallée
,
A. Cosson
,
M. Doudeau
,
F. Godin
,
A. Champiré
FEBS Meeting 2019, Jul 2019, Cracovie, Poland
Conference poster
hal-02924140v1
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Neurofibromin, a new SUMO target involved in neurofibromatosis type 1 disease
M. Bergoug
,
I. Sošic
,
M. Doudeau
,
F. Godin
,
Béatrice Vallée
EMBO Workshop "The ubiquitin system: Biology, mechanisms and roles in disease", Sep 2019, Cavtat, Croatia
Conference poster
hal-02924095v1
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Molecular and functional characterization of LIMK2-1, a hominidae-specific isoform of LIMK2 associated with intellectual disability
H. Bénédetti
,
Béatrice Vallée
,
J. Tastet
,
H. Cubéros
,
A. Toutain
NeuroFrance 2019, May 2019, Marseille, France
Conference poster
hal-02924881v1
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Study of the different forms of sumoylation of the neurofibromin SecPH domain
H. Bénédetti
,
M. Bergoug
,
I. Sošic
,
M. Doudeau
,
F. Godin
EMBO Workshop "The ubiquitin system: Biology, mechanisms and roles in disease", Sep 2019, Cavtat, Croatia
Conference poster
hal-02924090v1
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Yeast biosensors to detect environmental pollutants into effluent waters
Christine Mosrin-Huaman
,
B. Handelaoui
,
H. Bénédetti
,
Béatrice Vallée
ICYGMB XXIX International Congress on Yeast Genetics and Molecular Biology, Aug 2019, Göteborg, Sweden
Conference poster
hal-02924111v1
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LARP6, a RNA−binding protein involved in translation and stability of collagen mRNA, is a new partner of Neurofibromin: Molecular studies and functional implications
H. Bénédetti
,
M. Doudeau
,
F. Godin
,
Béatrice Vallée
,
A. Cosson
Joint Global Neurofibromatosis Conference 2018, Nov 2018, Paris, France
Conference poster
hal-02924084v1
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Development of small molecule inhibitors of LIM kinases, new therapeutic targets to treat Neurofibromatosis type I
Béatrice Vallée
,
A. Cosson
,
M. Doudeau
,
F. Godin
,
A. Champiré
Joint Global Neurofibromatosis Conference 2018, Nov 2018, Paris, France
Conference poster
hal-02924077v1
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LIM Kinases: new anticancer therapeutic targets
Béatrice Vallée
,
A. Cosson
,
M. Doudeau
,
F. Godin
,
Anthony Champiré
Breast Cancer Symposium, Jun 2017, Nantes, France
Conference poster
hal-03680148v1
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Study of the sumoylation of neurofibromin, the protein responsible for neurofibromatosis type 1
M. Bergoug
,
A. Cosson
,
M. Doudeau
,
F. Godin
,
Béatrice Vallée
EMBO Conference "Ubiquitin and SUMO: from molecular mechanisms to system-wide responses, Sep 2017, Cavtat, Croatia
Conference poster
hal-02924070v1
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Design, synthesis and biological evaluation of LIMK inhibitors
A. Champiré
,
A. Braka
,
Béatrice Vallée
,
M. Doudeau
,
F. Godin
XXIVe Journées Jeunes Chercheurs (SCT), Feb 2017, Châtenay-Malabry, France
Conference poster
hal-02904837v1
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LINGO-1, a protein involved in various neurodevelopmental processes, interacts with neurofibromin (Nf1), the protein responsible for neurofibromatosis type I: molecular studies and functional implications
Hélène Bénédetti
,
Fabienne Godin
,
Michel Doudeau
,
Béatrice Vallée
,
Marie-Ludivine De Tauzia
10 th FENS (Forum of Neuroscience), Jul 2016, Copenhague, Denmark
Conference poster
hal-02453487v1
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The three isoforms of human LIMK2 regulate actin cytoskeleton remodeling via different pathways
Béatrice Vallée
,
Hélène Cuberos
,
Michel Doudeau
,
Fabienne Godin
,
Patrick Vourc’h
EMBL Symposium, Actin in action: From Molecules to Cellular Functions, Sep 2016, Heidelberg, Germany.
Conference poster
hal-02453489v1
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LIM kinases: new therapeutic targets to treat Neurofibromatosis type I
Béatrice Vallée
,
Michel Doudeau
,
Fabienne Godin
,
Anthony Champiré
,
Karen Plé
The 7th EMBO meeting, Sep 2016, Mannheim, Germany.
Conference poster
hal-02453490v1
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Projet Région LiCorNe: LIMK protein inhibitors, new therapeutic agents for treatment of cognitive disorders associated with type I Neurofibromatosis
Béatrice Vallée
,
Michel Doudeau
,
F. Godin
,
H. Cubéros
,
A. Champiré
Journée Fédération PCV FR2708, Jan 2016, Orléans, France
Conference poster
hal-02924056v1
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Conception, synthèse et évaluation biologique d’inhibiteurs de LIM kinases
A. Champiré
,
A. Braka
,
Béatrice Vallée
,
M. Doudeau
,
F. Godin
29e colloque de Biotechnocentre, Oct 2016, Seillac, France
Conference poster
hal-02904847v1
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LIMK2-1, a new primate-specific isoform of LIMK2, is associated with intellectual disability
Béatrice Vallée
,
Hélène Cuberos
,
Julie Tastet
,
Michel Doudeau
,
Fabienne Godin
10 th FENS (Forum of Neurosciences), Jul 2016, Copenhague, Denmark.
Conference poster
hal-02453486v1
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