BENJAMIN CHAGOT

Publications

Article dans une revue (25)

Protocol for the purification, analysis, and handling of acyl carrier proteins from type I fatty acid and polyketide synthases Christian Gusenda,Svenja Berlage,Ines Burkhart,Benjamin Chagot,Kira J. Weissmanet al. STAR Protocols, 2025, 6 (2), pp.103762. ⟨10.1016/j.xpro.2025.103762⟩ Article dans une revue hal-05051199v1
Insights into docking in megasynthases from the investigation of the toblerol trans -AT polyketide synthase: many α-helical means to an end Serge Scat,Kira Weissman,Benjamin Chagot RSC Chemical Biology, 2024, 5 (7), pp.669-683. ⟨10.1039/d4cb00075g⟩ Article dans une revue hal-04644892v1
Decrypting the programming of β-methylation in virginiamycin M biosynthesis Sabrina Collin,Russell Cox,Cédric Paris,Christophe Jacob,Benjamin Chagotet al. Nature Communications, 2023, 14 (1), pp.1327. ⟨10.1038/s41467-023-36974-3⟩ Article dans une revue hal-04064366v1
Towards improved understanding of intersubunit interactions in modular polyketide biosynthesis: Docking in the enacyloxin IIa polyketide synthase Fanny Risser,Sabrina Collin,Raphael dos Santos-Morais,Arnaud Gruez,Benjamin Chagotet al. Journal of Structural Biology, 2020, 212 (1), pp.107581. ⟨10.1016/j.jsb.2020.107581⟩ Article dans une revue hal-02926190v1
Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis Jonathan Dorival,Fanny Risser,Christophe Jacob,Sabrina Collin,Gerald Drägeret al. Nature Communications, 2018, 9 (1), pp.3998. ⟨10.1038/s41467-018-06323-w⟩ Article dans une revue hal-01980537v1
Characterization of Intersubunit Communication in the Virginiamycin trans-Acyl Transferase Polyketide Synthase Jonathan Dorival,Thibault Annaval,Fanny Risser,Sabrina Collin,Pierre Roblinet al. Journal of the American Chemical Society, 2016, 138 (12), pp.4155-4167. ⟨10.1021/jacs.5b13372⟩ Article dans une revue hal-01452317v1
Bacteriophage SPP1 tail tube protein self-assembles into β-structure-rich tubes. Chantal Langlois,Stéphanie Ramboarina,Abhishek Cukkemane,Isabelle Auzat,Benjamin Chagotet al. Journal of Biological Chemistry, 2015, 290 (6), pp.3836-49. ⟨10.1074/jbc.M114.613166⟩ Article dans une revue hal-01449521v1
Insights into the function of trans-acyl transferase polyketide synthases from the SAXS structure of a complete module Jack Davison,Jonathan Dorival,Hery Rabeharindranto,Hortense Mazon,Benjamin Chagotet al. Chemical Science, 2014, 5 (8), pp.3081-3095. ⟨10.1039/c3sc53511h⟩ Article dans une revue hal-01453210v1
Function of polyketide synthases from the SAXS structure of a complete module Jack Davison,Jonathan Dorival,Hery Rabeharindranto,Hortense Mazon,Benjamin Chagotet al. Acta Crystallographica Section A : Foundations and Advances [2014-..], 2014, 70 (a1), pp.C407 - C407. ⟨10.1107/S2053273314095928⟩ Article dans une revue hal-01653555v1
Inhibition of Histone Deacetylase 3 Causes Replication Stress in Cutaneous T Cell Lymphoma Christina Wells,Srividya Bhaskara,Kristy R. Stengel,Yue Zhao,Bianca Sirbuet al. PLoS ONE, 2013, 8 (7), ⟨10.1371/journal.pone.0068915⟩ Article dans une revue hal-01637728v1
NMR studies of the interaction of calmodulin with IQ motif peptides. Steven Damo,Michael D Feldkamp,Benjamin Chagot,Walter J Chazin Methods in Molecular Biology, 2013, Calcium-Binding Proteins and RAGE 963, pp.173-86. ⟨10.1007/978-1-62703-230-8_11⟩ Article dans une revue hal-01637792v1
Solution structure of gp17 from the Siphoviridae bacteriophage SPP1: Insights into its role in virion assembly Benjamin Chagot,Isabelle Auzat,Matthieu Gallopin,Isabelle Petitpas,Bernard Gilquinet al. Proteins - Structure, Function and Bioinformatics, 2012, 80 (1), pp.319 - 326. ⟨10.1002/prot.23191⟩ Article dans une revue istex hal-01637793v1
Solution NMR Structure of Apo-Calmodulin in Complex with the IQ Motif of Human Cardiac Sodium Channel NaV1.5 Benjamin Chagot,Walter J. Chazin Journal of Molecular Biology, 2011, 406 (1), pp.106 - 119. ⟨10.1016/j.jmb.2010.11.046⟩ Article dans une revue hal-01636790v1
Solution NMR Structure of the C-terminal DNA Binding Domain of Mcm10 Reveals a Conserved MCM Motif Patrick Robertson,Benjamin Chagot,Walter J. Chazin,Brandt F. Eichman Journal of Biological Chemistry, 2010, 285 (30), pp.22942 - 22949. ⟨10.1074/jbc.M110.131276⟩ Article dans une revue hal-01637795v1
Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin Franck Potet,Benjamin Chagot,Mircea Anghelescu,Prakash C. Viswanathan,Svetlana Z. Stepanovicet al. Journal of Biological Chemistry, 2009, 284 (13), pp.8846 - 8854. ⟨10.1074/jbc.M806871200⟩ Article dans une revue hal-01637798v1
Solution NMR Structure of the C-terminal EF-hand Domain of Human Cardiac Sodium Channel Na V 1.5 Benjamin Chagot,Franck Potet,Jeffrey R. Balser,Walter J. Chazin Journal of Biological Chemistry, 2009, 284 (10), pp.6436 - 6445. ⟨10.1074/jbc.M807747200⟩ Article dans une revue hal-01636789v1
Structure-Function Analysis of Inositol Hexakisphosphate-induced Autoprocessing in Clostridium difficile Toxin A Rory Pruitt,Benjamin Chagot,Michael Cover,Walter J. Chazin,Ben Spilleret al. Journal of Biological Chemistry, 2009, 284 (33), pp.21934 - 21940. ⟨10.1074/jbc.M109.018929⟩ Article dans une revue hal-01637796v1
Solution structure of PcFK1, a spider peptide active against Plasmodium falciparum Cyril Pimentel,Soo-Jin Choi,Benjamin Chagot,Catherine Guette,Jean-Michel Camadroet al. Protein Science, 2006, 15(3), pp.628-34. ⟨10.1110/ps.051860606⟩ Article dans une revue hal-00018558v1
Calcium-Dependent Regulation of Ion Channels. Vikas N Shah,Benjamin Chagot,Walter J Chazin Calcium binding proteins, 2006, pp.203-212 Article dans une revue hal-01652606v1
An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis Benjamin Chagot,Cyril Pimentel,Li Dai,Joost Pil,Jan Tytgatet al. Biochemical Journal, 2005, 388 (1), pp.263-271. ⟨10.1042/BJ20041705⟩ Article dans une revue hal-01636774v1
Increasing the molecular contacts between maurotoxin and Kv1.2 channel augments ligand affinity. Sarrah M'Barek,Benjamin Chagot,Nicolas Andreotti,Violeta Visan,Pascal Mansuelleet al. Proteins - Structure, Function and Bioinformatics, 2005, 60 (3), pp.401-11. ⟨10.1002/prot.20509⟩ Article dans une revue istex inserm-00381749v1
Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels Benjamin Chagot,Pierre Escoubas,Sylvie Diochot,Cedric Bernard,Michel Lazdunskiet al. Protein Science, 2005, 14 (8), pp.2003-2010. ⟨10.1110/ps.051378905⟩ Article dans une revue hal-01636767v1
Solution structure of APETx1 from the sea anemone Anthopleura elegantissima: A new fold for an HERG toxin Benjamin Chagot,Sylvie Diochot,Cyril Pimentel,Michel Lazdunski,Hervé Darbon Proteins - Structure, Function and Bioinformatics, 2005, 59 (2), pp.380 - 386. ⟨10.1002/prot.20425⟩ Article dans une revue istex hal-01636397v1
Solution structure of two insect-specific spider toxins and their pharmacological interaction with the insect voltage-gated Na+ channel G. Ferrat,F. Bosmans,J. Tytgat,C. Pimentel,Benjamin Chagotet al. Proteins - Structure, Function and Bioinformatics, 2005, 59 (2), pp.368 - 379. ⟨10.1002/prot.20424⟩ Article dans une revue istex hal-01636782v1
Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus Benjamin Chagot,Pierre Escoubas,Elba Villegas,Cedric Bernard,Gilles Ferratet al. Protein Science, 2004, 13 (5), pp.1197-1208. ⟨10.1110/ps.03584304⟩ Article dans une revue hal-01636765v1

Communication dans un congrès (7)

Decision making in polyketide biosynthesis Kira J. Weissman,Arnaud Gruez,Sabrina Collin,Christophe Jacob,Benjamin Chagotet al. Metabolic and Protein Engineering for Biosynthesis (MaPED) Conference, Nov 2024, Francfort, Germany Communication dans un congrès hal-05390072v1
Structure-function relationships in modular PKSs and their application to genetic engineering Kira J Weissman,Fanny Risser,Jean-Malo Massicard,Sabrina Collin,Raphael dos Santos Moraiset al. MegaSyn Symposium, 2020, Bad Nauheim, Germany Communication dans un congrès hal-02956682v1
Are the ubiquitous mitochondrial glutaredoxin-like proteins of 12 kDa (MGP12) true glutaredoxins? Tiphaine Dhalleine,Mathieu Schwartz,Marc Quinternet,Benjamin Chagot,Benjamin Petreet al. Thiol-based switches and redox regulation – from microbes to men, Sep 2019, San Feliu de Guixols, Spain Communication dans un congrès hal-03197996v1
Decrypting structure-function relationships in modular PKSs Kira J Weissman,Jack Davison,Jonathan Dorival,Thibault Annaval,Fanny Risseret al. From mutases to megasynthases: celebrating the career of Professor Peter Leadlay. Retirement symposium for Prof. Peter Leadlay., 2018, Cambridge, United Kingdom Communication dans un congrès hal-03016899v1
The structural biology of modular polyketide synthases: insights and implications for synthetic biology Kira J Weissman,Jack Davison,Jonathan Dorival,Thibault Annaval,Fanny Risseret al. 3rd European Conference on Natural Products, 2018, Frankfurt, Germany Communication dans un congrès hal-02956684v1
The structural biology of modular polyketide synthases: insights and implications for synthetic biology Kira J. Weissman,Jonathan Dorival,Thibault Annaval,Fanny Risser,Sabrina Collinet al. European Workshop on Natural Product Biosynthesis, Jun 2017, Gif-sur-Yvete, France Communication dans un congrès hal-01736000v1
Deciphering the structures of trans-AT polyketide synthases Kira J. Weissman,Jack Davison,Jonathan Dorival,Thibault Annaval,Fanny Risseret al. BMWZ Symposium, Sep 2016, Hannover, Germany Communication dans un congrès hal-01735998v1