Benoit Arcangioli

26
Documents

Présentation

Benoit Arcangioli

6 March 1959, Age 63 (November 2022),

Married two children.

Director of the Dynamic of the Genome Unit at the Pasteur Institute, Paris, France.

Professor at the Pasteur Institute

EDUCATION

1984-1986 PhD student, Moshe Yaniv Laboratory, Pasteur Institute, Paris Cité Université.

1988 PhD thesis; Moshe Yaniv Laboratory, Pasteur Institute, Paris Cité Université

1994 HDR, Paris Cité Université.

RESEARCH and PRofessional EXPERIENCE.

1980-1982 Chemist Cabot Carbone

1987 Visiting scientist Leonard Guarente MIT, Boston, USA

1987 Roux Foundation fellowship, Pasteur Institute

1988-1991 Research Assistant, Pasteur Institute

1988-1989 Independent Group Leader entitled: Yeast Molecular Genetic Group

1989-1991 EMBO post-doctoral fellowship, Amar Klar, NCI, Frederick, USA

1991-1999 Full Researcher, Pasteur Institute

1999-2021 Laboratory Director, Pasteur Institute

2001-present Director of the Unit entitled: Dynamics of the Genome

2010 Visiting scientist, Robert Martienssen, CSHL, USA

2022-present Professor at the Pasteur Institute

TEACHING AND MENTORING ACTIVITIES

2005-present Co-director of Pasteur Course entitled: Molecular Genetics and Epigenetics

Lecturer in Virology (cell cycle), Microbiology (Genetics of quiescence) courses (Pasteur)

Organized two EMBO courses on fission yeast in 2012 and 2014 (2 weeks).

Participated to 10 EMBO courses.

MOOC E-learning on epigenetics

Teaching for LSLEAD “Life Sciences Leadership School” (2015-2020)

Supervised 8 PhD students (1 ongoing), 4 Postdocs (1 ongoing)

Invited two professors for sabbatical visit (R. Martienssen (CSHL, USA) and K. Ekwall, Karolinska SWE).

MEETING ORGANIZATION

Co-organized the two following meeting series:

“Levures, Modèles et outils” (3 meetings, Brussels, Geneva and Paris 2001-2003-2006

3Rs” for: “Replication, recombination and repair”, (4 meetings, Presqu’Île de Giens 2004-2012

Co-organized the “Genetics, Epigenetics and Evolution of sex Chromosomes” Paris 9-10th June 2011

Co-organized the 50th anniversary of the Replicon Theory (Institut Pasteur, Paris March 25-28, 2013)

Co-organized the symposium of Blaise Pascal Chair for Robert Martienssen; entitled « Lamarck, Landmarks and Landscapes: frontiers in epigenetics » (Institut Pasteur, Paris February 18th 2014).

Co-organized 7 departmental retreats

Regularly since 2010, I’m Chairman in the S. pombe international meeting series

Ongoing: Chairman “Aging and Metabolism” Hiroshima (JPN) 28 May-2 June, 2023.

COMMITTEES & ADMINISTRATION

2009-2012. Secretary of the Replicon Club, Société Française de Biochimie et Biologie Moléculaire.

2006-2012. Member of the National Committee (2) of the Cancer Research Association (ARC)

2012- Member of the “Comité Colloques, Institut Pasteur”

Elected member at the COMESP (2012-2016), Head of committee 1 (Genetics and Biochemistry)

Member of HCERES committee (2018; 2019)

2014-present Twice elected member of the Assembly of 100 of Pasteur Institute, Member of the “bureau”

Vice-President of the ANR agency committee (2018-2021): “DNA, RNA and epigenetics”

Member of the jury of more than 60 PhD theses and 6 HDRs, in France and abroad.

Editorial board: Microbial Cell (2017-present).

HONORS & AWARDS

1986 Prize Jacques Monod (Institut Pasteur)

2007 Prize Pasteur Vallery-Radot

2014 Prize Thérèse Lebrasseur

Publications

Publications

Deposit thumbnail

Hypomorphic mutations in ura6 confer 5-FOA resistance in fission yeast

Constance Kowal , Ying Liu , Claire Denis , Benoît Arcangioli , Stefania Francesconi et al.

PLoS ONE, 2026, 21 (3), pp.e0344121. ⟨10.1371/journal.pone.0344121⟩

Article dans une revue hal-05541899v1
Deposit thumbnail

The quiescent X, the replicative Y and the Autosomes

Guillaume Achaz , Serge Gangloff , Benoît Arcangioli

Peer Community Journal, 2022, 2, pp.e18. ⟨10.24072/pcjournal.99⟩

Article dans une revue hal-03771709v1
Deposit thumbnail

Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation

Elie Hammam , Ameya Sinha , Sebastian Baumgarten , Flore Nardella , Jiaqi Liang et al.

mBio, 2021, 12, pp.e02558-21. ⟨10.1128/mBio.02558-21⟩

Article dans une revue pasteur-03427780v1
Deposit thumbnail

Nitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways

Rostyslav Makarenko , Claire Denis , Stefania Francesconi , Serge Gangloff , Benoît Arcangioli

Nature Communications, 2020, 11 (1), pp.1973. ⟨10.1038/s41467-020-15880-y⟩

Article dans une revue pasteur-02573577v1
Deposit thumbnail

Leo1 is essential for the dynamic regulation of heterochromatin and gene expression during cellular quiescence

Eriko Oya , Mickaël Durand-Dubief , Adiel Cohen , Vladimir Maksimov , Catherine Schurra et al.

Epigenetics & Chromatin, 2019, 12 (1), pp.45. ⟨10.1186/s13072-019-0292-7⟩

Article dans une revue pasteur-02545917v1
Deposit thumbnail

Molecular signature of the imprintosome complex at the mating-type locus in fission yeast.

Célia Raimondi , Bernd Jagla , Caroline Proux , Hervé Waxin , Serge Gangloff et al.

Microbial Cell , 2018, 5 (4), pp.169 - 183. ⟨10.15698/mic2018.04.623⟩

Article dans une revue pasteur-01868255v1
Deposit thumbnail

DNA repair and mutations during quiescence in yeast

Serge Gangloff , Benoît Arcangioli

FEMS Yeast Research, 2017, 17 (1), ⟨10.1093/femsyr/fox002⟩

Article dans une revue pasteur-01868274v1
Deposit thumbnail

Transcriptional reprogramming in cellular quiescence

Benjamin Roche , Benoît Arcangioli , Robert Martienssen

RNA Biology, 2017, 14 (7), pp.843 - 853. ⟨10.1080/15476286.2017.1327510⟩

Article dans une revue pasteur-01868271v1
Deposit thumbnail

New roles for Dicer in the nucleolus and its relevance to cancer

Benjamin Roche , Benoît Arcangioli , Robert Martienssen

Cell Cycle, 2017, 16 (18), pp.1643-1653. ⟨10.1080/15384101.2017.1361568⟩

Article dans une revue pasteur-02013965v1
Deposit thumbnail

Quiescence unveils a novel mutational force in fission yeast

Serge Gangloff , Guillaume Achaz , Stefania Francesconi , Adrien Villain , Samia Miled et al.

eLife, 2017, 6, pp.e27469. ⟨10.7554/eLife.27469⟩

Article dans une revue hal-01678930v1
Deposit thumbnail

Eroded telomeres are rearranged in quiescent fission yeast cells through duplications of subtelomeric sequences.

Laetitia Maestroni , Julien Audry , Samah Matmati , Benoît Arcangioli , Vincent Géli et al.

Nature Communications, 2017, ⟨10.1038/s41467-017-01894-6⟩

Article dans une revue hal-01788868v1
Deposit thumbnail

RNA interference is essential for cellular quiescence

B. Roche , Benoît Arcangioli , R. Martienssen

Science, 2016, 354 (6313), ⟨10.1126/science.aah5651⟩

Article dans une revue pasteur-01868276v1
Deposit thumbnail

Activation induced cytidine deaminase mutant (AID-His130Pro) from Hyper IgM 2 patient retained mutagenic activity on SHM artificial substrate

Hanen Ouadani , Imen Benmustapha , Meriem Ben-Ali , Beya Larguèche , Tihana Jovanic et al.

Molecular Immunology, 2016, 79, pp.77 - 82. ⟨10.1016/j.molimm.2016.09.025⟩

Article dans une revue pasteur-01453058v1
Deposit thumbnail

Regulating retrotransposon activity through the use of alternative transcription start sites

Jenna Persson , Babett Steglich , Agata Smialowska , Mette Boyd , Jette Bornholdt et al.

EMBO Reports, 2016, 17 (5), pp.753 - 768. ⟨10.15252/embr.201541866⟩

Article dans une revue pasteur-01868286v1
Deposit thumbnail

How to choose the right mate

Benoît Arcangioli

PLoS Genetics, 2013, 9 (10), pp.e1003881. ⟨10.1371/journal.pgen.1003881⟩

Article dans une revue pasteur-02013959v1
Deposit thumbnail

Lsd1 and lsd2 control programmed replication fork pauses and imprinting in fission yeast

Allyson M. Holmes , Laura Roseaulin , Catherine Schurra , Hervé Waxin , Sarah Lambert et al.

Cell Reports, 2012, 2 (6), pp.1513-1520. ⟨10.1016/j.celrep.2012.10.011⟩

Article dans une revue pasteur-02013826v1

Lsd1 and Lsd2 Control Programmed Replication Fork Pauses and Imprinting in Fission Yeast

Allyson Holmes , Laura Roseaulin , Catherine Schurra , Herve Waxin , Sarah Lambert et al.

Cell Reports, 2012, 2 (6), pp.1513-1520. ⟨10.1016/j.celrep.2012.10.011⟩

Article dans une revue hal-03009029v1
Deposit thumbnail

RNAi promotes heterochromatic silencing through replication-coupled release of RNA Pol II

Mikel Zaratiegui , Stephane E. Castel , Danielle V. Irvine , Anna Kloc , Jie Ren et al.

Nature, 2011, 479 (7371), pp.135-138. ⟨10.1038/nature10501⟩

Article dans une revue pasteur-02013927v1
Deposit thumbnail

CENP-B preserves genome integrity at replication forks paused by retrotransposon LTR

Mikel Zaratiegui , Matthew W Vaughn , Danielle V. Irvine , Derek Goto , Stephen Watt et al.

Nature, 2011, 469 (7328), pp.112-115. ⟨10.1038/nature09608⟩

Article dans une revue pasteur-02013953v1
Deposit thumbnail

Checkpoint-dependent and -independent roles of Swi3 in replication fork recovery and sister chromatid cohesion in fission yeast

Jordan B. Rapp , Chiaki Noguchi , Mukund M. Das , Lisa K. Wong , Alison B. Ansbach et al.

PLoS ONE, 2010, 5 (10), pp.e13379. ⟨10.1371/journal.pone.0013379⟩

Article dans une revue pasteur-02013890v1

Role of SUMO in the dynamics of telomere maintenance in fission yeast

Blerta Xhemalce , Eva Madi Riising , Peter Baumann , Anne Dejean , Benoît Arcangioli et al.

Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (3), pp.893-898. ⟨10.1073/pnas.0605442104⟩

Article dans une revue pasteur-03236974v1

Role of the fission yeast SUMO E3 ligase Pli1p in centromere and telomere maintenance

Blerta Xhemalce , Jacob-Sebastian Seeler , Geneviève Thon , Anne Dejean , Benoît Arcangioli

EMBO Journal, 2004, 23 (19), pp.3844-3853. ⟨10.1038/sj.emboj.7600394⟩

Article dans une revue pasteur-03237018v1

The nucleotide sequence of the PRII gene related to DNA primase in Saccharomyces cerevisiae

Rostyslav Makarenko , Claire Denis , Stefania Francesconi , Serge Gangloff , Benoît Arcangioli

Nucleic Acids Research, 1987, 15 (19), pp.7975-7989. ⟨10.1093/nar/15.19.7975⟩

Article dans une revue hal-03007979v1