Bertrand DUBREUCQ

Identifiants chercheurs

IdHAL :

bertrand-dubreucq

ORCID :

0000-0003-2661-5479

IdRef :

158519965

Présentation

Equipe SeeDev, UMR 1318 Institut Jean Pierre Bourgin, INRA, centre de Versailles

From my past and present research achievements, I have acquired a good expertise in plant molecular genetics. My technical skills are based on the tools of molecular biology, cytology and bioinformatics and serve to answer biological questions involving seed development. My main topic is the transcriptional network controlling the switch between embryogenesis and accumulation of reserves. I am focusing on LEC2, a master regulator of seed maturation belonging to the B3 family. My work aims to determine (i) how this factor binds, or interact, with its DNA targets, in a possible complex with ABI3 and FUS3, (ii) how is this protein complex is regulated, and (iii) how LEC2 is transcriptionnaly and post-transcriptionally tuned. We aim at modelling the regulatory network involved in Arabidopsis and investigate how it is conserved in cereals.

Scientific manager of the cytology and imaging platform of the Plant Observatory, I ensure the proper scientific and human functioning of a strategic tool for my institute (1200M2, 5 Full Time Equivalents, 100 regular users, 5 confocal micoscopes, laser microdissector, twenty large optic pieces, and various cytology-related materials http://www.versailles-grignon.inra.fr/pciv). Operating correspondent for the institute, I manage all aspects of the unit's 9 buildings (8000M2), requests for equipment, works, modifications, in relations with the research center for all these aspects. I am also managing the unit’s workshop (3 FTEs).

Publications

Article dans une revue (49)

The characterization of the LEAFY COTYLEDON 2 activation domains reveals its conserved dual mode of action in flowering plants Camille Salaün,Johanne Thévenin,Angèle Edoura-Gaena,Yichun Qiu,Jasmine Burguetet al. The Plant Journal, 2025, 123 (4), ⟨10.1111/tpj.70380⟩ Article dans une revue hal-05217878v1
Tracing 100 million years of grass genome evolutionary plasticity Arnaud Bellec,Mamadou Dia Sow,Caroline Pont,Peter Civan,Emile Mardocet al. The Plant Journal, 2023, 114 (6), pp.1243-1266. ⟨10.1111/tpj.16185⟩ Article dans une revue hal-04305473v1
Recent progress in molecular genetics and omics-driven research in seed biology Sébastien Baud,Massimiliano Corso,Isabelle Debeaujon,Bertrand Dubreucq,Dominique Jobet al. Comptes Rendus. Biologies, 2023, 345, pp.61 - 110. ⟨10.5802/crbiol.104⟩ Article dans une revue hal-05263353v1
Custom methods to identify conserved genetic modules applied to novel transcriptomic data from Amborella trichopoda Ana Rivarola Sena,Amélie Andres-Robin,Aurélie Vialette,Jérémy Just,Alexandra Launay-Avonet al. Journal of Experimental Botany, 2022, 73 (8), pp.2487-2498. ⟨10.1093/jxb/erac044⟩ Article dans une revue hal-03566722v1
The Seed Development Factors TT2 and MYB5 Regulate Heat Stress Response in Arabidopsis Pierre Jacob,Gwilherm Brisou,Marion Dalmais,Johanne Thévenin,Froukje van Der Walet al. Genes, 2021, 12 (5), pp.1-18. ⟨10.3390/genes12050746⟩ Article dans une revue hal-03335244v1
Genetic and Molecular Control of Somatic Embryogenesis Camille Salaün,Loïc Lepiniec,Bertrand Dubreucq Plants, 2021, 10 (7), pp.1467. ⟨10.3390/plants10071467⟩ Article dans une revue hal-03754308v1
Variation in expression of the HECT E3 ligase UPL3 modulates LEC2 levels, seed size, and crop yields in brassica napus Charlotte Miller,Rachel Wells,Neil Mckenzie,Martin Trick,Joshua Ballet al. The Plant cell, 2019, 31 (10), pp.2370-2385. ⟨10.1105/tpc.18.00577⟩ Article dans une revue hal-02622699v1
Regulation of FUSCA3 Expression During Seed Development in Arabidopsis Thomas James Roscoe,Virginie Vaissayre,Gaël Paszkiewicz,Fernando Clavijo,Zsolt Kelemenet al. Plant and Cell Physiology, 2019, 60 (2), pp.476-487. ⟨10.1093/pcp/pcy224⟩ Article dans une revue hal-02386031v1
Combining laser-assisted microdissection (LAM) and RNA-seq allows to perform a comprehensive transcriptomic analysis of epidermal cells of Arabidopsis embryo Kaori Sakai,Ludivine Taconnat,Néro Borrega,Jennifer Yansouni,Véronique Brunaudet al. Plant Methods, 2018, 14, pp.10. ⟨10.1186/s13007-018-0275-x⟩ Article dans une revue hal-02625394v1
LEC1 (NF-YB9) directly interacts with LEC2 to control gene expression in seed Céline Boulard,Johanne Thévenin,O. Tranquet,V. Laporte,L. Lepiniecet al. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2018, 1861 (5), pp.443-450. ⟨10.1016/j.bbagrm.2018.03.005⟩ Article dans une revue hal-01746034v1
Molecular and epigenetic regulations and functions of the LAFL transcriptional regulators that control seed development L. Lepiniec,M. Devic,T. Roscoe,D. Bouyer,D.-X Zhouet al. Sexual Plant Reproduction, 2018, 31 (3), pp.291-307. ⟨10.1007/s00497-018-0337-2⟩ Article dans une revue hal-01969458v1
Regulation and evolution of the interaction of the seed B3 transcription factors with NF-Y subunits Céline Boulard,Abdelhak Fatihi,Loic Lepiniec,Bertrand Dubreucq Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2017, 1860 (10), pp.1069-1078. ⟨10.1016/j.bbagrm.2017.08.008⟩ Article dans une revue hal-02627256v1
The Physcomitrella patens System for Transient Gene Expression Assays. Johanne Thévenin,Wenjia Xu,Louise Vaisman,Loic Lepiniec,Bertrand Dubreucqet al. Methods in Molecular Biology, 2016, 1482, pp.151-61. ⟨10.1007/978-1-4939-6396-6_10⟩ Article dans une revue hal-01389059v1
La caméline, une plante modèle pour la recherche translationnelle Mark Tepfer,Bertrand Dubreucq,Jean-Denis Faure Biofutur, 2016, 380, pp.38-41 Article dans une revue hal-01529235v1
Deciphering the molecular mechanisms underpinning the transcriptional control of gene expression by L-AFL proteins in Arabidopsis seed. Sebastien S. Baud,Zsolt Kelemen,Johanne Thévenin,Celine Boulard,Sandrine Blanchetet al. Plant Physiology, 2016, 171 (171), pp.1099-1112. ⟨10.1104/pp.16.00034⟩ Article dans une revue hal-01406124v1
Role of B3 domain transcription factors of the AFL family in maize kernel filling Aurélie Grimault,Ghislaine Gendrot,Sandrine Chaignon,Françoise Gilard,Guillaume Tcherkezet al. Plant Science, 2015, 236, pp.116-125. ⟨10.1016/j.plantsci.2015.03.021⟩ Article dans une revue hal-01204180v1
Analysis of the DNA-Binding Activities of the Arabidopsis R2R3-MYB Transcription Factor Family by One-Hybrid Experiments in Yeast Zsolt Kelemen,Alvaro Sebastian,Wenjia Xu,Damaris Grain,Fabien Salsacet al. PLoS ONE, 2015, 10 (10), pp.e0141044. ⟨10.1371/journal.pone.0141044⟩ Article dans une revue hal-01837546v1
Imaging and quantitative analysis of size and distribution of sperical bodies, [i]e.g[/i]. embryonic oil bodies Martine Miquel,Ghassen Trigui,Alain Trubuil,Bertrand Dubreucq Bio-protocol , 2015, 5 (1), pp.1-6 Article dans une revue (article de synthèse) hal-01204094v1
ZmZHOUPI, an endosperm-specific basic helix-loop-helix transcription factor involved in maize seed development Aurélie Grimault,Ghislaine Gendrot,Sophy Chamot,Thomas Widiez,Hervé Rabilléet al. The Plant Journal, 2015, 84 (3), pp.574-586. ⟨10.1111/tpj.13024⟩ Article dans une revue hal-01536562v1
The structural organization of seed oil bodies could explain the contrasted oil extractability observed in two rapeseed genotypes. Celine Boulard,Michel Bardet,Thierry Chardot,Bertrand Dubreucq,Marina Gromovaet al. Planta, 2015, 242 (1), pp.53-68. ⟨10.1007/s00425-015-2286-4⟩ Article dans une revue hal-01204182v1
Function and localization of the Arabidopsis thaliana diacylglycerol acyltransferase DGAT2 expressed in yeast Laure Aymé,Sebastien S. Baud,Bertrand Dubreucq,Florent Joffre,Thierry Chardot PLoS ONE, 2014, 9 (3), 9 p. ⟨10.1371/journal.pone.0092237⟩ Article dans une revue hal-01204016v1
MYB118 Represses Endosperm Maturation in Seeds of Arabidopsis Guillaume Barthole,Alexandra To,Chloé Marchive,Véronique Brunaud,Ludivine Soubigou-Taconnatet al. The Plant cell, 2014, 26 (9), pp.3519 - 3537. ⟨10.1105/tpc.114.130021⟩ Article dans une revue hal-01204153v1
Endosperm breakdown in Arabidopsis requires heterodimers of the basic helix-loop-helix proteins ZHOUPI and INDUCER OF CBP EXPRESSION 1 Gregoire Denay,Audrey Creff,Steven Moussu,Pauline Wagnon,Johanne Théveninet al. Development (Cambridge, England), 2014, 141 (6), pp.1222-U85. ⟨10.1242/dev.103531⟩ Article dans une revue hal-01204028v1
Specialization of Oleosins in Oil Body Dynamics during Seed Development in Arabidopsis Seeds Martine Miquel,Ghassen Trigui,Sabine D’andrea,Zsolt Kelemen,Sébastien Baudet al. Plant Physiology, 2014, 164 (4), pp.1866-1878. ⟨10.1104/pp.113.233262⟩ Article dans une revue hal-03659033v1
A comprehensive overview of grain development in Brachypodium distachyon variety Bd21 Fabienne Guillon,Colette Larre,Fabrice Petitpas,Adeline Berger,Jihad Moussawiet al. Journal of Experimental Botany, 2012, 63 (2), pp.739-755. ⟨10.1093/jxb/err298⟩ Article dans une revue hal-01190419v1
The dynamics of oil bodies in Arabidopsis thaliana seeds : a mathematical model of biogenesis and coalescence Ghassen Trigui,Béatrice Laroche,Martine Miquel,Bertrand B. Dubreucq,Alain Trubuil International Journal of Electrical, Computer, Energetic, Electronic and Communication Engineering, 2012, 64, pp.763-768 Article dans une revue hal-02643123v1
A new system for fast and quantitative analysis of heterologous gene expression in plants Johanne Thévenin,Christian Dubos,Wenjia Xu,José Gentilhomme-Le Gourrierec,Zolt Kelemenet al. New Phytologist, 2012, 193 (2), pp.504 - 512. ⟨10.1111/j.1469-8137.2011.03936.x⟩ Article dans une revue hal-01004263v1
Evolution goes GAGA: GAGA binding proteins across kingdoms Nathalie Berger,Bertrand B. Dubreucq Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2012, 1819 (8), pp.863 - 868. ⟨10.1016/j.bbagrm.2012.02.022⟩ Article dans une revue istex hal-01004142v1
Expression variation in connected recombinant populations of Arabidopsis thaliana highlights distinct transcriptome architectures Francisco Cubillos,Jennifer Yansouni,Ahmid Khalili,Sandrine Balzergue,Samira Elftiehet al. BMC Genomics, 2012, 13, pp.1-12. ⟨10.1186/1471-2164-13-117⟩ Article dans une revue hal-01189696v1
Transcriptional regulation of Arabidopsis LEAFY COTYLEDON2 involves RLE,a cis-element that regulates Trimethylation of Histone H3 at Lysine-27 Nathalie Berger,Bertrand B. Dubreucq,François Roudier,Christian C. Dubos,Loic L. Lepiniec The Plant cell, 2011, 23 (11), pp.4065-4078. ⟨10.1105/tpc.111.087866⟩ Article dans une revue hal-01000017v1
Arabidopsis seed secrets unravelled after a decade of genetic and omics-driven research Helen North,Sebastien S. Baud,Isabelle Debeaujon,Christian Dubos,Bertrand Dubreucqet al. The Plant Journal, 2010, 61 (6), pp.971-981. ⟨10.1111/j.1365-313X.2009.04095.x⟩ Article dans une revue hal-01203892v1
NOF1 encodes an arabidopsis protein involved in the control of rRNA expression Erwana Harscoet,Bertrand Dubreucq,Jean-Christophe Palauqui,Loic Lepiniec PLoS ONE, 2010, 5 (9), pp.e12829. ⟨10.1371/journal.pone.0012829⟩ Article dans une revue hal-01203890v1
Arabidopsis seed secrets unravelled after a decade of genetic and omics‐driven research Helen North,Sébastien Baud,Isabelle Debeaujon,Christian Dubos,Bertrand Dubreucqet al. The Plant Journal, 2010, 61 (6), pp.971 - 981. ⟨10.1111/j.1365-313x.2009.04095.x⟩ Article dans une revue hal-05263460v1
High-resolution whole-mount imaging of three-dimensional tissue organization and gene expression enables the study of Phloem development and structure in Arabidopsis. Elisabeth Truernit,Hélène Bauby,Bertrand Dubreucq,Olivier Grandjean,John Runionset al. The Plant cell, 2008, 20 (6), pp.1494-1503. ⟨10.1105/tpc.107.056069⟩ Article dans une revue hal-02663189v1
Deciphering gene regulatory networks that control seed development and maturation in Arabidopsis. Monica Santos-Mendoza,Bertrand Dubreucq,Sebastien S. Baud,François Parcy,Michel Cabocheet al. The Plant Journal, 2008, 54 (4), pp.608-20. ⟨10.1111/j.1365-313X.2008.03461.x⟩ Article dans une revue hal-00297574v1
WRINKLED1 specifies the regulatory action of LEAFY COTYLEDON2 towards fatty acid metabolism during seed maturation in Arabidopsis Sebastien S. Baud,Monica Santos Mendoza,Alexandra A. To,Erwana E. Harscoet,Loic L. Lepiniecet al. The Plant Journal, 2007, 50 (5), pp.825-838. ⟨10.1111/j.1365-313X.2007.03092.x⟩ Article dans une revue hal-02664890v1
Function of plastidial pyruvate kinases in seeds of Arabidopsis thaliana Sebastien S. Baud,Sylvie Wuilleme,Bertrand B. Dubreucq,Aurélie de Almeida,Cindy Vuagnatet al. The Plant Journal, 2007, 52 (3), pp.405-419. ⟨10.1111/j.1365-313X.2007.03232.x⟩ Article dans une revue hal-02661879v1
LEAFY COTYLEDON 2 activation is sufficient to trigger the accumulation of oil and seed specific mRNAs in Arabidopsis leaves Monica Santos-Mendoza,Bertrand B. Dubreucq,Martine Miquel,Michel M. Caboche,Loic L. Lepiniec FEBS Letters, 2005, 579 (21), pp.4666-4670. ⟨10.1016/j.febslet.2005.07.037⟩ Article dans une revue hal-02682706v1
TT2, TT8 and TTG1 synergistically specify the expression of BANYULS and proanthocyanidin biosynthesis in Arabidopsis A. Baudry,M.A. Heim,Bertrand B. Dubreucq,B. Weisshaar,Loic L. Lepiniec The Plant Journal, 2004, 39 (3), pp.366-380. ⟨10.1111/j.1365-313X.2004.02138.x⟩ Article dans une revue hal-02683484v1
T-DNA integration into Arabidopsis genome depends on sequences of pre-insertion sites Véronique Brunaud,Sandrine Balzergue,Bertrand B. Dubreucq,Sebastien Aubourg,Franck Samsonet al. EMBO Reports, 2002, 3 (12), pp.1152-1157. ⟨10.1093/embo-reports/kvf237⟩ Article dans une revue hal-02682810v1
The AtRbx1 protein is part of plant SCF complexes, and its down-regulation causes severe growth and developmental defects Esther Lechner,Daoxin Xie,Sandrine Grava,Emmanuelle Pigaglio,Séverine Planchaiset al. Journal of Biological Chemistry, 2002, 277 (51), pp.50069-50080. ⟨10.1074/jbc.M204254200⟩ Article dans une revue hal-02682424v1
FLAGdb/FST: a database of mapped flanking insersion sites (FSTs) of Arabidopsis thaliana T-DNA transformants Franck Samson,Véronique Brunaud,Sandrine Balzergue,Bertrand B. Dubreucq,Loic L. Lepiniecet al. Nucleic Acids Research, 2002, 30 (1), pp.94-97 Article dans une revue hal-02678939v1
The AtRbx1 Protein Is Part of Plant SCF Complexes, and Its Down-regulation Causes Severe Growth and Developmental Defects Esther Lechner,Daoxin Xie,Sandrine Grava,Emmanuelle Pigaglio,Severine Planchaiset al. Journal of Biological Chemistry, 2002, 277 (51), pp.50069-50080. ⟨10.1074/jbc.M204254200⟩ Article dans une revue hal-05491771v1
Arabidopsis glucosidase I mutants reveal a critical role of N-glycan trimming in seed development M. Boisson,Veronique Gomord,Corinne Audran,Nathalie Berger,Bertrand B. Dubreucqet al. EMBO Journal, 2001, 20 (5), pp.1010-1019 Article dans une revue hal-02683628v1
Approches moléculaires de la qualité et du développement des graines Bertrand B. Dubreucq,Philippe Grappin,Martine Miquel,Helen North,Christine Rochatet al. Oléagineux, Corps Gras, Lipides, 2001, 8 (5), pp.487-495 Article dans une revue hal-02674355v1
Improved PCR-walking for large-scale isolation of plant T-DNA borders Sandrine Balzergue,Bertrand B. Dubreucq,Sylvie Chauvin,I. Le-Clainche,F. Le Boulaireet al. Biotechniques, 2001, 30 (3), 3 p Article dans une revue hal-02670631v1
The Arabidopsis AtPRP1 extensin-like gene is specifically expressed in endosperm during seed germination Bertrand B. Dubreucq,Nathalie Berger,E. Vincent,M. Boisson,G. Pelletieret al. The Plant Journal, 2000, 5, pp.643-652 Article dans une revue hal-02688788v1
La germination vient en dormant Michel M. Caboche,Bertrand B. Dubreucq,Philippe Grappin,P. Lepiniec,Nathalie Nesi Biofutur, 1998, 175, pp.32-35 Article dans une revue hal-02689896v1
A new method for the identification and isolation of genes essential for Arabidopsis thaliana seed germination Bertrand B. Dubreucq,Philippe Grappin,Michel M. Caboche Molecular and General Genetics MGG, 1996, 252, pp.42-50 Article dans une revue hal-02692047v1

Communication dans un congrès (11)

Elucidating the role of nf-yb transcription factors in pea seed development Yara Noureddine,Christine Le Signor,Johanne Thévenin,Myriam Sanchez,Titouan Bonnotet al. ILS4 Fourth International Legume Society Conference 2023, Sep 2023, Grenade, Spain Communication dans un congrès hal-04223020v1
Shared Task SeeDev : Extraction de régulations impliquées dans le développement de la graine d’Arabidopsis thaliana à partir de publications scientifiques Estelle Chaix,Bertrand Dubreucq,Dialekti Valsamou,Abdelhak Fatihi,Louise Delegeret al. Les journées Bioinformatique de l'Inra, Mar 2016, Montpellier, France. pp.1 Communication dans un congrès hal-01455855v1
Overview of the regulatory network of plant seed development (SeeDev) task at the BioNLP shared task 2016 Estelle Chaix,Bertrand Dubreucq,Abdelhak Fatihi,Dialekti Valsamou,Robert Bossyet al. BioNLP Shared Task, Aug 2016, Berlin, Germany. pp.113 Communication dans un congrès hal-01455854v1
Information extraction challenge Gene Regulation Network in Arabidopsis thaliana (GRNA) Estelle Chaix,Bertrand Dubreucq,Dialekti Valsamou,Abdelhak Fatihi,Robert Bossyet al. Paris-Saclay Center for Data Science: Open Software Initiative (OSI), Oct 2015, Orsay, France. pp.14 slides, ⟨10.13140/RG.2.1.4286.6326⟩ Communication dans un congrès hal-01603453v1
Information extraction from articles for the elaboration of the regulatory networks involved in Arabidopsis seed development Bertrand Dubreucq,Dialekti Valsamou,Abdelhak Fatihi,Estelle Chaix,Robert Bossyet al. 26th International Conference on Arabidopsis Research, Jul 2015, Paris, France Communication dans un congrès hal-01524850v1
Knowledge model of regulatory networks involved in Arabidopsis seed development for information extraction and integration from text Estelle Chaix,Bertrand Dubreucq,Dialekti Valsamou,Abdelhak Fatihi,Robert Bossyet al. BioCreative 5, Sep 2015, Madrid, Spain Communication dans un congrès hal-01512197v1
Analysis of factors affecting the growth of oil bodies in A. Thaliana seeds: use of ordinary least squares and quantile regression Ghassen Trigui,Martine Miquel,Bertrand B. Dubreucq,Olivier David,Alain Trubuil The 10th International Workshop on Computational Systems Biology, WCSB 2013, Jun 2013, Tampere, Finland. pp.144 Communication dans un congrès hal-02748214v1
The dynamics of oil bodies in A. thaliana seeds :A mathematical model of biogenesis and coalescence Ghassen Trigui,Béatrice Laroche,Martine Miquel,Bertrand Dubreucq,Alain Trubuil ICMB 2012 - VIII International Conference on Mathematical Biology, Labo/service de l'auteur, Ville service., Apr 2012, Paris, France. pp.763-768 Communication dans un congrès hal-01019421v1
Brachypodium distachyon grain: development-associated changes in morphology and storage accumulation Colette Larre,Anne-Laure Chateigner Boutin,Brigitte Bouchet,Fabrice Petitpas,Hélène Rogniauxet al. 1. European Brachypodium Workshop, Oct 2011, Versailles, France Communication dans un congrès hal-02809921v1
L'alimentation des vaches est susceptible de modifier les caractéristiques sensorielles du lait Bertrand B. Dubreucq,B. Martin,Anne Ferlay,Philippe Pradel,Isabelle Verdier-Metzet al. 9. Rencontres Recherches Ruminants, Dec 2002, Paris, France Communication dans un congrès hal-02761189v1
Isolation and characterization of Arabidopsis mutants affected in seed development or germination Loic L. Lepiniec,Sandrine Balzergue,Nicole Bechtold,M. Boisson,Bertrand B. Dubreucqet al. 9. International conference on Arabidopsis research, Jun 1998, Madison, United States Communication dans un congrès hal-02765356v1

Ouvrages (1)

Enhancer and gene-trapping in Arabidopsis thaliana, as tool to identify molecular markers of seed germination Bertrand B. Dubreucq,C. Vroemen,Loic L. Lepiniec,S. de Vries,Michel M. Cabocheet al. 5 p., 1999 Ouvrages hal-02841906v1

Chapitre d'ouvrage (2)

Seed Development B. Dubreucq,S. Baud,I. Debeaujon,C. Dubos,A. Marion-Pollet al. Plant Developmental Biology - Biotechnological Perspectives, Springer Berlin Heidelberg, pp.341-359, 2010, 978-3-642-02300-2. ⟨10.1007/978-3-642-02301-9_17⟩ Chapitre d'ouvrage hal-05263499v1
Seed Development Bertrand Dubreucq,Sebastien S. Baud,Isabelle Debeaujon,Christian Dubos,Annie Marion-Pollet al. Plant Developmental Biology - Biotechnological Perspectives, Springer-verlag, 497 p., 2010, 978-3-642-02300-2. ⟨10.1007/978-3-642-02301-9_17⟩ Chapitre d'ouvrage hal-01203968v1

Brevet (1)

DISPOSITIF D'EXTRACTION DE LIQUIDE DEPUIS UNE SUBSTANCE NOTAMMENT DEPUIS DES GRAINES OLEAGINEUSES Yannick Bellec,Bertrand Dubreucq,Jean-Denis Faure,Martine Miquel France, N° de brevet: 1461385. 2014 Brevet hal-01529245v1

Autre publication scientifique (1)

Annotation Guidelines BIONLP-ST 2016 SeeDev task Estelle Chaix,Bertrand B. Dubreucq,Dialekti Valsamou,Abdelhak Fatihi,Louise Delegeret al. 2016, pp.47 Autre publication scientifique hal-02795594v1