Bertrand Dubois

Publications

Article dans une revue (38)

Neoadjuvant immune checkpoint blockade before chemoradiation for cervical squamous carcinoma (GINECO window-of-opportunity COLIBRI study): a phase II trial Isabelle Ray-Coquard,Marie-Christine Kaminsky-Forrett,Ryotaro Ohkuma,Aymeric de Montfort,Florence Jolyet al. Nature Communications, 2026, ⟨10.1038/s41467-025-67646-z⟩ Article dans une revue hal-05471803v1
Neoadjuvant immune checkpoint blockade before chemoradiation for cervical squamous carcinoma (GINECO window-of-opportunity COLIBRI study): a phase II trial Isabelle Ray-Coquard,Marie-Christine Kaminsky-Forrett,Ryotaro Ohkuma,Aymeric de Montfort,Florence Jolyet al. Nature Communications, 2026, 17 (1), pp.922. ⟨10.1038/s41467-025-67646-z⟩ Article dans une revue hal-05527505v1
Immune landscape and TAM density in endometrial cancer: implications for immune checkpoint inhibitors efficacy Olivia Le Saux,Renaud Sabatier,Isabelle Treilleux,Léa-Isabelle Renaud,Pierre-Emmanuel Brachetet al. Therapeutic Advances in Medical Oncology, 2025, 17, pp.17588359251347364. ⟨10.1177/17588359251347364⟩ Article dans une revue hal-05223627v1
Unraveling the Tumor Microenvironment and PD-L1 Expression across Tissue Types in High-Grade Serous Ovarian Cancer in the NeoPembrOV/GINECO Phase II Randomized Trial Laetitia Collet,Maude Ardin,David Venet,Justine Berthet,Sarah Ghamry-Barrinet al. Clinical Cancer Research, 2025, pp.OF1-OF15. ⟨10.1158/1078-0432.CCR-24-2712⟩ Article dans une revue hal-05156766v1
The spatial organization of cDC1 with CD8+ T cells is critical for the response to immune checkpoint inhibitors in melanoma patients Elisa Gobbini,Margaux Hubert,Anne-Claire Doffin,Anais Eberhardt,Léo Hermetet al. Cancer Immunology Research, 2025, ⟨10.1158/2326-6066.CIR-24-0421⟩ Article dans une revue hal-04879746v1
Phase I First-in-Human Study of TRK-950, an IgG1 Antibody Specific to CAPRIN-1, in Patients with Advanced Solid Tumors Philippe A Cassier,Mitesh J Borad,Sunil Sharma,Bertrand Dubois,Christophe Cauxet al. Cancer Research Communications, 2025, 5 (7), pp.1119 - 1128. ⟨10.1158/2767-9764.crc-25-0123⟩ Article dans une revue hal-05305400v1
Modulation of blood T cell polyfunctionality and HVEM/BTLA expression are critical determinants of clinical outcome in anti-PD1-treated metastatic melanoma patients Stéphane Dalle,Estelle Verronese,Axelle N’kodia,Christine Bardin,Céline Rodriguezet al. OncoImmunology, 2024, 13 (1), pp.2372118. ⟨10.1080/2162402X.2024.2372118⟩ Article dans une revue hal-04632685v1
Immunomic longitudinal profiling of the NeoPembrOv trial identifies drivers of immunoresistance in high-grade ovarian carcinoma Olivia Le Saux,Maude Ardin,Justine Berthet,Sarah Barrin,Morgane Bourhiset al. Nature Communications, 2024, 15 (1), pp.5932. ⟨10.1038/s41467-024-47000-5⟩ Article dans une revue hal-04655437v1
The CSF-1R inhibitor pexidartinib affects FLT3-dependent DC differentiation and may antagonize durvalumab effect in patients with advanced cancers Aurélien Voissière,Carlos Gomez-Roca,Sylvie Chabaud,Céline Rodriguez,Axelle Nkodiaet al. Science Translational Medicine, 2024, 16 (731), ⟨10.1126/scitranslmed.add1834⟩ Article dans une revue hal-04645010v1
KIR2DL2/DL3+NKs and Helios+Tregs in peripheral blood predict nivolumab response in patients with metastatic renal cell cancer Sara Santagata,Anna Maria Trotta,Crescenzo d'Alterio,Maria Napolitano,Giuseppina Reaet al. Clinical Cancer Research, 2024, ⟨10.1158/1078-0432.CCR-24-0729⟩ Article dans une revue hal-04675471v1
Structures lymphoïdes tertiaires : de la biogenèse à l’impact thérapeutique en cancérologie Stanislas Quesada,Coriolan Lebreton,Christophe Caux,Antoine Italiano,Bertrand Dubois Bulletin du Cancer, 2023, 110 (6), pp.657-664. ⟨10.1016/j.bulcan.2023.04.010⟩ Article dans une revue hal-04879774v1
Pembrolizumab in Lymphopenic Metastatic Breast Cancer Patients Treated with Metronomic Cyclophosphamide: A Clinical and Translational Prospective Study Benoîte Mery,Christine Ménétrier-Caux,Laure Montané,Pierre-Etienne Heudel,Isabelle Ray-Coquardet al. Breast Cancer, 2023, 15, pp.311 - 325. ⟨10.2147/bctt.s400055⟩ Article dans une revue hal-04210158v1
Different Genetic Signatures of Small‐Cell Lung Cancer Characterize &lt;scp&gt;Anti‐GABA&lt;sub&gt;B&lt;/sub&gt;R&lt;/scp&gt; and &lt;scp&gt;Anti‐Hu&lt;/scp&gt; Paraneoplastic Neurological Syndromes Alberto Vogrig,Antoine Pegat,Macarena Villagrán‐garcía,Valentin Wucher,Valéry Attignonet al. Annals of Neurology, 2023, 94 (6), pp.1102 - 1115. ⟨10.1002/ana.26784⟩ Article dans une revue hal-04401076v1
ZEB1 transcription factor promotes immune escape in melanoma Maud Plaschka,Valentin Benboubker,Maxime Grimont,Justine Berthet,Laurie Tononet al. Journal for Immunotherapy of Cancer, 2022, 10 (3), pp.e003484. ⟨10.1136/jitc-2021-003484⟩ Article dans une revue hal-03769027v1
Genomic Instability Is Defined by Specific Tumor Microenvironment in Ovarian Cancer: A Subgroup Analysis of AGO OVAR 12 Trial Jean-David Fumet,Emilie Lardenois,Isabelle Ray-Coquard,Philipp Harter,Florence Jolyet al. Cancers, 2022, 14 (5), pp.1189. ⟨10.3390/cancers14051189⟩ Article dans une revue hal-03769697v1
Heterogeneity and Functions of Tumor-Infiltrating Antibody Secreting Cells: Lessons from Breast, Ovarian, and Other Solid Cancers Yasmine Lounici,Olivia Le Saux,Gabriel Chemin,Pauline Wajda,Sarah Barrinet al. Cancers, 2022, 14 (19), pp.4800. ⟨10.3390/cancers14194800⟩ Article dans une revue hal-04882857v1
Immune and Genetic Signatures of Breast Carcinomas Triggering Anti-Yo–Associated Paraneoplastic Cerebellar Degeneration Elise Peter,Isabelle Treilleux,Valentin Wucher,Emma Jougla,Alberto Vogriget al. Neurology Neuroimmunology & Neuroinflammation, 2022, 9 (5), pp.e200015. ⟨10.1212/nxi.0000000000200015⟩ Article dans une revue hal-03915422v1
Neoadjuvant immune checkpoint inhibitors in cancer, current state of the art Olivia Le Saux,Yasmine Lounici,Pauline Wajda,Sarah Barrin,Christophe Cauxet al. Critical Reviews in Oncology/Hematology, 2021, 157, pp.103172 -. ⟨10.1016/j.critrevonc.2020.103172⟩ Article dans une revue hal-03492630v1
Actualités en recherche en oncologie : l'essentiel du 4e Symposium International 2019 du Centre de Recherche en Cancérologie de Lyon Frédéric Catez,Nicole Dalla Venezia,Jean-Jacques Diaz,Bertrand Dubois,Anthony Ferrariet al. Bulletin du Cancer, 2020, 107 (1), pp.136-140. ⟨10.1016/j.bulcan.2019.12.002⟩ Article dans une revue hal-03004269v1
IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer Margaux Hubert,Elisa Gobbini,Coline Couillault,Thien-Phong Vu Manh,Anne-Claire Doffinet al. Science Immunology, 2020, 5 (46), pp.eaav3942. ⟨10.1126/sciimmunol.aav3942⟩ Article dans une revue hal-02998632v1
Les avancées actuelles de l’immunothérapie dans le cancer de l’ovaire Olivia Le Saux,Bertrand Dubois,Marc-Henri Stern,Magali Terme,Eric Tartouret al. Bulletin du Cancer, 2020, 107, pp.465 - 473. ⟨10.1016/j.bulcan.2019.11.015⟩ Article dans une revue hal-03490307v1
Immunopathological characterization of ovarian teratomas associated with anti-N-methyl-D-aspartate receptor encephalitis Aude Chefdeville,Isabelle Treilleux,Marie-Eve Mayeur,Coline Couillault,Géraldine Picardet al. Acta Neuropathologica Communications, 2019, 7, pp.38. ⟨10.1186/s40478-019-0693-7⟩ Article dans une revue hal-02083563v1
Hepatitis B Virus Blocks the CRE/CREB Complex and Prevents TLR9 Transcription and Function in Human B Cells Issam Tout,Melissa Gomes,Michelle Ainouze,Marie Marotel,Timothee Pecoulet al. Journal of Immunology, 2018, 201 (8), pp.2331-2344. ⟨10.4049/jimmunol.1701726⟩ Article dans une revue hal-04941080v1
Autocrine Adenosine regulates tumor polyfunctional CD73+CD4+ effector T cells devoid of immune checkpoints Nicolas Gourdin,Marion Bossennec,Céline Rodriguez,Selena Vigano,Christelle Machonet al. Cancer Research, 2018, 78 (13), pp.3604-3618. ⟨10.1158/0008-5472.CAN-17-2405⟩ Article dans une revue hal-02285966v1
Intestinal dendritic cell licensing through Toll-like receptor 4 is required for oral tolerance in allergic contact dermatitis Feriel Hacini-Rachinel,Mercedes Gomez de Agüero,Reem Kanjarawi,Ludovic Moro-Sibilot,Jean-Benoît Le Luduecet al. Journal of Allergy and Clinical Immunology, 2018, 141 (1), pp.163-170. ⟨10.1016/j.jaci.2017.02.022⟩ Article dans une revue hal-02046249v1
Identification of Tertiary Lymphoid Structure-Associated Follicular Helper T Cells in Human Tumors and Tissues Coline Couillault,Claire Germain,Bertrand Dubois,Hélène Kaplon Methods in Molecular Biology, 2018, Methods in Molecular Biology, 1845, pp.205-222. ⟨10.1007/978-1-4939-8709-2_12⟩ Article dans une revue hal-04003929v1
Mélanome métastatique Camille Fourneaux,Bertrand Dubois Médecine/Sciences, 2018, 34 (10), pp.875-878. ⟨10.1051/medsci/2018219⟩ Article dans une revue hal-02970086v1
Genetic alterations and tumor immune attack in Yo paraneoplastic cerebellar degeneration Mathilde Small,Isabelle Treilleux,Coline Couillault,Daniel Pissaloux,Géraldine Picardet al. Acta Neuropathologica, 2018, 135 (4), pp.569-579. ⟨10.1007/s00401-017-1802-y⟩ Article dans une revue hal-04998090v1
Intradermal immunisation using the TLR3-ligand Poly (I:C) as adjuvant induces mucosal antibody responses and protects against genital HSV-2 infection Emilie Bardel,Remi Doucet-Ladeveze,Cyrille Mathieu,Ali M. Harandi,Bertrand Duboiset al. NPJ vaccines, 2016, 1, pp.16010. ⟨10.1038/npjvaccines.2016.10⟩ Article dans une revue hal-01911476v1
Plasmacytoid dendritic cells are dispensable for noninfectious intestinal IgA responses in vivo Ludovic Moro-Sibilot,Sébastien This,Pascal Blanc,Amelien Sanlaville,Vanja Sisiraket al. European Journal of Immunology, 2016, 46, pp.354--359. ⟨10.1002/eji.201545977⟩ Article dans une revue hal-01812673v1
Intradermal vaccination with un-adjuvanted sub-unit vaccines triggers skin innate immunity and confers protective respiratory immunity in domestic swine Jean-Benoît Le Luduec,Sabine Debeer,Fabienne Piras,Christine Andréoni,Florence Boudetet al. Vaccine, 2016, 34 (7), pp.914-922. ⟨10.1016/j.vaccine.2015.12.058⟩ Article dans une revue istex hal-01911477v1
Mouse and Human Liver Contain Immunoglobulin A–Secreting Cells Originating From Peyer's Patches and Directed Against Intestinal Antigens Ludovic Moro-Sibilot,Pascal Blanc,Morgan Taillardet,Emilie Bardel,Coline Couillaultet al. Gastroenterology, 2016, 151 (2), pp.311-323. ⟨10.1053/j.gastro.2016.04.014⟩ Article dans une revue hal-02046134v1
S1PR5 is pivotal for the homeostasis of patrolling monocytes. Emilie Debien,Katia Mayol,Vincent Biajoux,Cécile Daussy,Mercedes Gomez de Agueroet al. European Journal of Immunology, 2013, 43 (6), pp.1667-75. ⟨10.1002/eji.201343312⟩ Article dans une revue hal-00972078v1
Regulatory T Cells Control Type I Food Allergy to Beta-Lactoglobulin in Mice Reem Kanjarawi,Christophe Dercamp,Nathalie Etchart,Karine Adel-Patient,Jean-François Nicolaset al. International Archives of Allergy and Immunology, 2011, 156 (4), pp.387 - 396. ⟨10.1159/000323940⟩ Article dans une revue hal-02645403v1
Characterization of a CD44/CD122int memory CD8 T cell subset generated under sterile inflammatory conditions. Florentin Martial Mbitikon-Kobo,Marc Vocanson,Marie-Cécile Michallet,Martine Tomkowiak,Anne Cottalordaet al. Journal of Immunology, 2009, 182 (6), pp.3846-54. ⟨10.4049/jimmunol.0802438⟩ Article dans une revue inserm-00392005v1
Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo. Marie Le Borgne,Nathalie Etchart,Anne Goubier,Sergio A. Lira,Jean Claude Sirardet al. Immunity, 2006, 24, pp.191-201. ⟨10.1016/j.immuni.2006.01.005⟩ Article dans une revue inserm-00000041v1
Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Adrien Kissenpfennig,Sandrine Henri,Bertrand Dubois,Corinne Laplace-Builhé,Pierre Perrinet al. Immunity, 2005, 22 (5), pp.643-54. ⟨10.1016/j.immuni.2005.04.004⟩ Article dans une revue hal-00165695v1
Dendritic Cells Enhance the Differentiation of Naive B Cells into Plasma Cells In Vitro Jérôme Fayette,Isabelle Durand,Jean-Michel Bridon,Christophe Arpin,Bertrand Duboiset al. Scandinavian Journal of Immunology, 1998, 48 (6), pp.563-570. ⟨10.1046/j.1365-3083.1998.00471.x⟩ Article dans une revue hal-02474199v1

Autre publication scientifique (1)

Breast Cancer Specificities of Patients With Anti-Ri Paraneoplastic Neurologic Syndromes Elise Peter,Isabelle Treilleux,Valentin Wucher,Macarena Villagrán-García,Pauline Dumezet al. 2025, ⟨10.1212/NXI.0000000000200367⟩ Autre publication scientifique hal-05274101v1

Communication dans un congrès (4)

The CSF-1R inhibitor Pexidartinib impacts dendritic cell differentiation through inhibition of FLT3 signaling and may antagonize the effect of durvalumab in patients with advanced cancer – results from a phase 1 study Céline Rodriguez,Aurélien Voissiere,Axelle Nkodia,Carlos Alberto Gomez-Roca,Sylvie Chabaudet al. 26e congrès annuel de l’AFC à Toulouse, Nov 2023, Toulouse, France Communication dans un congrès hal-04890819v1
Spatial organization and prognostic impact of dendritic cell subsets in a large cohort of triple negative breast cancer patients Elisa Gobbini,Margaux Hubert,Anne-Claire Doffin,Candice Sakref,Justine Berthetet al. Club Francophone des Cellules Dendritiques, Dec 2021, Paris, France Communication dans un congrès hal-04944901v1
Complementary but distinct protective roles of breast tumor infiltrating IgG and IgA producing cells Yasmine Lounici,Coline Couillault,Justine Berthet,Vincent Alcazer,Olivia Le Sauxet al. 53rd Annual Meeting of the French Society for Immunology, Dec 2021, Paris, France Communication dans un congrès hal-04968100v1
P11-05. Induction of CD8+ T cell mediated immune responses through skin and mucosa: identification of immunostimulatory versus tolerogenic dendritic cells Bertrand Dubois,Mercedes Gomez de Agüero,Marie Le Borgne,Marie Gouanvic,Marc Vocansonet al. AIDS Vaccine 2009, Oct 2009, Paris, France. pp.P150, ⟨10.1186/1742-4690-6-S3-P150⟩ Communication dans un congrès inserm-00663585v1