Boris Hejblum

74
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Publications

Publications

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Self-collected finger-prick blood for gene expression profiling: Unveiling early immune responses in mild COVID-19

Rodolphe Thiébaut , Edouard Lhomme , Hakim Hocini , Isabelle Pellegrin , Andrea Boizard-Moracchini et al.

iScience, 2025, 29 (2), pp.114593. ⟨10.1016/j.isci.2025.114593⟩

Article dans une revue hal-05490229v1
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Reservoir Computing in R: a Tutorial for Using reservoirnet to Predict Complex Time-Series

Thomas Ferté , Kalidou Ba , Dan Dutartre , Pierrick Legrand , Vianney Jouhet et al.

Computo, 2025, ⟨10.57750/arxn-6z34⟩

Article dans une revue hal-05208084v1
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RISE: Two-Stage Rank-Based Identification of High-Dimensional Surrogate Markers Applied to Vaccinology

Arthur Hughes , Layla Parast , Rodolphe Thiébaut , Boris P. Hejblum

Statistics in Medicine, 2025, 44 (20-22), pp.e70241. ⟨10.1002/sim.70241⟩

Article dans une revue hal-04933460v2
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A strategy for multimodal integration of transcriptomics, proteomics, and radiomics data for the prediction of recurrence in patients with IDH-mutant gliomas

Tiffanie Chouleur , Christèle Etchegaray , Laura Villain , Antoine Lesur , Thomas Ferté et al.

International Journal of Cancer, 2025, 157 (3), pp.573-587. ⟨10.1002/ijc.35441⟩

Article dans une revue hal-05069366v1
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On the potential benefits of entropic regularization for smoothing Wasserstein estimators

Jérémie Bigot , Paul Freulon , Boris P. Hejblum , Arthur Leclaire

Electronic Journal of Statistics , 2025, 19 (2), pp.3867-3894. ⟨10.1214/25-EJS2430⟩

Article dans une revue hal-03908229v1
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Post-clustering difference testing: valid inference and practical considerations

Benjamin Hivert , Denis Agniel , Rodolphe Thiébaut , Boris P. Hejblum

Computational Statistics and Data Analysis, 2024, 193, pp.107916. ⟨10.1016/j.csda.2023.107916⟩

Article dans une revue hal-03889565v1

ChatGPT et au-delà avec l’intelligence artificielle en santé : des leçons à tirer

Rodolphe Thiébaut , Boris P. Hejblum , Fleur Mougin , Christophe Tzourio , Laura Richert

Revue du Rhumatisme, 2024, 91 (1), pp.12-15. ⟨10.1016/j.rhum.2023.07.007⟩

Article dans une revue hal-04466670v1
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Neglecting normalization impact in semi-synthetic RNA-seq data simulation generates artificial false positives

Boris Hejblum , Kalidou Ba , Rodolphe Thiébaut , Denis Agniel

Genome Biology, 2024, 25 (1), pp.281. ⟨10.1101/2022.05.10.490529⟩

Article dans une revue hal-03908246v1
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Clonal succession after prolonged antiretroviral therapy rejuvenates CD8<sup>+</sup> T cell responses against HIV-1

Eoghann White , Laura Papagno , Assia Samri , Kenji Sugata , Boris P. Hejblum et al.

Nature Immunology, 2024, 25 (9), pp.1555-1564. ⟨10.1038/s41590-024-01931-9⟩

Article dans une revue hal-04703528v1
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Modéliser la COVID-19 : de la population à l’individu

Carole Vignals , Boris P. Hejblum , Mélanie Prague

Interstices, 2023

Article dans une revue hal-04230705v1
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ChatGPT and beyond with artificial intelligence (AI) in health: Lessons to be learned.

Rodolphe Thiebaut , Boris P. Hejblum , Fleur Mougin , Christophe Tzourio , Laura Richert

Joint Bone Spine, 2023, 90 (5), pp.105607. ⟨10.1016/j.jbspin.2023.105607⟩

Article dans une revue hal-04236822v1
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Using Population Based Kalman Estimator to Model COVID-19 Epidemic in France: Estimating the Effects of Non-Pharmaceutical Interventions on the Dynamics of Epidemic

Annabelle Collin , Boris P. Hejblum , Carole Vignals , Laurent Lehot , Rodolphe Thiébaut et al.

The international journal of biostatistics, In press, ⟨10.1515/ijb-2022-0087⟩

Article dans une revue hal-04151651v1
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CD177, a specific marker of neutrophil activation, is associated with coronavirus disease 2019 severity and death

Yves Lévy , Aurélie Wiedemann , Boris Hejblum , Mélany Durand , Cécile Lefebvre et al.

iScience, 2023, 26 (1), pp.105715. ⟨10.1016/j.isci.2022.105715⟩

Article dans une revue hal-04374099v1
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Doubly-robust evaluation of high-dimensional surrogate markers

Denis Agniel , Boris Hejblum , Rodolphe Thiébaut , Layla Parast

Biostatistics, 2023, 24 (4), pp.985-999. ⟨10.1093/biostatistics/kxac020⟩

Article dans une revue hal-03100499v1
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CytOpT: Optimal Transport with Domain Adaptation for Interpreting Flow Cytometry data

Paul Freulon , Jérémie Bigot , Boris Hejblum

Annals of Applied Statistics, 2023, 17 (2), pp.1086-1104. ⟨10.1214/22-AOAS1660⟩

Article dans une revue hal-03100405v1
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Identification of early gene expression profiles associated with long-lasting antibody responses to the Ebola vaccine Ad26.ZEBOV/MVA-BN-Filo

Fabiola Blengio , Hakim Hocini , Laura Richert , Cécile Lefebvre , Melany Durand et al.

Cell Reports, 2023, 42 (9), pp.113101. ⟨10.1016/j.celrep.2023.113101⟩

Article dans une revue hal-04273901v1

High temporal resolution transcriptomic profiling delineates distinct patterns of interferon response following Covid-19 mRNA vaccination and SARS-CoV2 infection

Darawan Rinchai , Sara Deola , Gabriele Zoppoli , Basirudeen Syed Ahamed Kabeer , Sara Taleb et al.

Science Advances , 2022, 8 (45), eabp9961. ⟨10.1126/sciadv.abp9961⟩

Article dans une revue hal-03530948v1

T Cell Immunogenicity, Gene Expression Profile, and Safety of Four Heterologous Prime-Boost Combinations of HIV Vaccine Candidates in Healthy Volunteers: Results of the Randomized Multi-Arm Phase I/II ANRS VRI01 Trial

Laura Richert , Jean-Daniel Lelievre , Christine Lacabaratz , Lucile Hardel , Hakim Hocini et al.

Journal of Immunology, 2022, 208 (12), pp.2663-2674. ⟨10.4049/jimmunol.2101076⟩

Article dans une revue hal-03690137v1
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The benefit of augmenting open data with clinical data-warehouse EHR for forecasting SARS-CoV-2 hospitalizations in Bordeaux area, France

Thomas Ferté , Vianney Jouhet , Romain Griffier , Boris P Hejblum , Rodolphe Thiébaut et al.

JAMIA open, 2022, 5 (4), ⟨10.1093/jamiaopen/ooac086⟩

Article dans une revue hal-03908260v1
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EpidemiOptim: a Toolbox for the Optimization of Control Policies in Epidemiological Models

Cédric Colas , Boris P. Hejblum , Sébastien Rouillon , Rodolphe Thiébaut , Pierre-Yves Oudeyer et al.

Journal of Artificial Intelligence Research, 2021, 71, pp.479-515. ⟨10.1613/jair.1.12588⟩

Article dans une revue hal-03099898v2
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Automatic phenotyping of electronical health record: PheVis algorithm

Thomas Ferté , Sébastien Cossin , Thierry Schaeverbeke , Thomas Barnetche , Vianney Jouhet et al.

Journal of Biomedical Informatics, 2021, 117, pp.103746. ⟨10.1016/j.jbi.2021.103746⟩

Article dans une revue hal-03100435v1
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CD177, a specific marker of neutrophil activation, is associated with coronavirus disease 2019 severity and death

Yves Lévy , Aurélie Wiedemann , Boris P. Hejblum , Mélany Durand , Cécile Lefebvre et al.

iScience, 2021, 24 (7), pp.102711. ⟨10.1016/j.isci.2021.102711⟩

Article dans une revue hal-03477973v1
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Predicting Progression to Advanced Age-Related Macular Degeneration from Clinical, Genetic, and Lifestyle Factors Using Machine Learning

Soufiane Ajana , Audrey Cougnard-Grégoire , Johanna Colijn , Bénédicte M.J. Merle , Timo Verzijden et al.

Ophthalmology: Journal of The American Academy of Ophthalmology, 2021, 128 (4), pp.587-597. ⟨10.1016/j.ophtha.2020.08.031⟩

Article dans une revue hal-03100320v1
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Bayesian mixture models for cytometry data analysis

Lin Lin , Boris Hejblum

Wiley Interdisciplinary Reviews: Computational Statistics, In press, 13 (4), pp.e1535. ⟨10.1002/wics.1535⟩

Article dans une revue hal-03100447v1
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Early signature in the blood lipidome associated with subsequent cognitive decline in the elderly: A case-control analysis nested within the Three-City cohort study

Sophie Lefevre-Arbogast , Boris P. Hejblum , Catherine Helmer , C. Klose , Claudine Manach et al.

EBioMedicine, 2021, 64, pp.103216. ⟨10.1016/j.ebiom.2021.103216⟩

Article dans une revue hal-03155026v1
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Robust and Efficient Optimization Using a Marquardt-Levenberg Algorithm with R Package marqLevAlg

Viviane Philipps , Boris P. Hejblum , Mélanie Prague , Daniel Commenges , Cécile Proust-Lima

The R Journal, In press, ⟨10.32614/RJ-2021-089⟩

Article dans une revue hal-03100489v1

ATLAS: an automated association test using probabilistically linked health records with application to genetic studies

Harrison Zhang , Boris P. Hejblum , Griffin Weber , Nathan Palmer , Susanne Churchill et al.

Journal of the American Medical Informatics Association, 2021, 28 (12), pp.2582-2592. ⟨10.1093/jamia/ocab187⟩

Article dans une revue hal-03478039v1
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Predicting the retinal content in omega‐3 fatty acids for age‐related macular‐degeneration

Niyazi Acar , Bénédicte M. J. Merle , Soufiane Ajana , Zhiguo He , Stéphane Grégoire et al.

Clinical and Translational Medicine, 2021, 11 (7), pp.e404. ⟨10.1002/ctm2.404⟩

Article dans une revue hal-03293612v1
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Long-lasting severe immune dysfunction in Ebola virus disease survivors

Aurélie Wiedemann , Emile Foucat , Hakim Hocini , Cécile Lefebvre , Boris Hejblum et al.

Nature Communications, 2020, 11 (1), pp.3730. ⟨10.1038/s41467-020-17489-7⟩

Article dans une revue hal-03160838v2
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Immune Alterations in a Patient with SARS-CoV-2-Related Acute Respiratory Distress Syndrome

Lila Bouadma , Aurélie Wiedemann , Juliette Patrier , Mathieu Surénaud , Paul-Henri Wicky et al.

Journal of Clinical Immunology, 2020, 40, pp.1082-1092. ⟨10.1007/s10875-020-00839-x⟩

Article dans une revue hal-03160737v2
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Analyzing cellular immunogenicity in vaccine clinical trials: a new statistical method including non-specific responses for accurate estimation of vaccine effect

Édouard Lhomme , Boris Hejblum , Christine Lacabaratz , Aurélie Wiedemann , Jean-Daniel Lelièvre et al.

Journal of Immunological Methods, 2020, 477, pp.112711. ⟨10.1016/j.jim.2019.112711⟩

Article dans une revue hal-03161945v2
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dearseq: a variance component score test for RNA-Seq differential analysis that effectively controls the false discovery rate

Marine Gauthier , Denis Agniel , Rodolphe Thiébaut , Boris Hejblum

NAR Genomics and Bioinformatics, 2020, 2 (4), pp.lqaa093. ⟨10.1093/nargab/lqaa093⟩

Article dans une revue hal-02138664v1
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Semi-supervised estimation of covariance with application to phenome-wide association studies with electronic medical records data

Stephanie F Chan , Boris P. Hejblum , Abhishek Chakrabortty , Tianxi Cai

Statistical Methods in Medical Research, 2020, 29 (2), pp.455-465. ⟨10.1177/0962280219837676⟩

Article dans une revue hal-02425459v1
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Probabilistic record linkage of de-identified research datasets with discrepancies using diagnosis codes

Boris P. Hejblum , Griffin M. Weber , Katherine P. Liao , Nathan P Palmer , Susanne Churchill et al.

Scientific Data , 2019, 6, pp.180298. ⟨10.1038/sdata.2018.298⟩

Article dans une revue hal-01942279v1
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Sequential Dirichlet Process Mixtures of Multivariate Skew t-distributions for Model-based Clustering of Flow Cytometry Data

Boris P. Hejblum , Chariff Alkhassim , Raphael Gottardo , François Caron , Rodolphe Thiébaut

Annals of Applied Statistics, 2019, 13 (1), pp.638-660. ⟨10.1214/18-AOAS1209⟩

Article dans une revue hal-01579063v1
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Benefits of dimension reduction in penalized regression methods for high dimensional grouped data: a case study in low sample size

Soufiane Ajana , Niyazi Acar , Lionel Brétillon , Boris Hejblum , Hélène Jacqmin-Gadda et al.

Bioinformatics, 2019, 35, pp.3628-3634. ⟨10.1093/bioinformatics/btz135⟩

Article dans une revue hal-02425449v1
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Sequential Dirichlet process mixture of skew $t$-distributions for model-based clustering of flow cytometry data

Boris P. Hejblum , Chariff Alkhassim , Raphael Gottardo , François Caron , Rodolphe Thiébaut

Annals of Applied Statistics, 2019, 13 (1), pp.638-660

Article dans une revue hal-03161057v1
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Diet-Related Metabolites Associated with Cognitive Decline Revealed by Untargeted Metabolomics in a Prospective Cohort

Dorrain Low , Sophie Lefèvre-Arbogast , Raúl Dominguez-Gonzalez , Mireia Urpi Sarda , Pierre Micheau et al.

Molecular Nutrition and Food Research, 2019, 63 (18), pp.e1900177. ⟨10.1002/mnfr.201900177⟩

Article dans une revue hal-02167524v1
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Gene Expression Signatures Associated With Immune and Virological Responses to Therapeutic Vaccination With Dendritic Cells in HIV-Infected Individuals

Rodolphe Thiébaut , Boris P. Hejblum , Hakim Hocini , Henri Bonnabau , Jason Skinner et al.

Frontiers in Immunology, 2019, 10, ⟨10.3389/fimmu.2019.00874⟩

Article dans une revue hal-02267014v2
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Association between anti-citrullinated fibrinogen antibodies and coronary artery disease in rheumatoid arthritis

Boris P. Hejblum , Jing Cui , Lauren J. Lahey , Andrew Cagan , Jeffrey A. Sparks et al.

Arthritis Care & Research = Arthritis Care and Research, 2018, 70 (7), pp.1113-1117. ⟨10.1002/acr.23444⟩

Article dans une revue hal-01654403v1
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PheProb: probabilistic phenotyping using diagnosis codes to improve power for genetic association studies

Jennifer A Sinnott , Fiona Cai , Sheng Yu , Boris P. Hejblum , Chuan Hong et al.

Journal of the American Medical Informatics Association, 2018, ⟨10.1093/jamia/ocy056⟩

Article dans une revue hal-01887930v1
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Pattern of polyphenol intake and the long-term risk of dementia in older persons

Sophie Lefèvre-Arbogast , David Gaudout , Julien Bensalem , Luc Letenneur , Jean-François Dartigues et al.

Neurology, 2018, 90 (22), pp.e1979 - e1988. ⟨10.1212/WNL.0000000000005607⟩

Article dans une revue hal-01887895v1
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cytometree: A binary tree algorithm for automatic gating in cytometry analysis

Daniel Commenges , Chariff Alkhassim , Raphael Gottardo , Boris P. Hejblum , Rodolphe Thiébaut

Cytometry Part A, 2018, 93 (11), pp.1132-1140. ⟨10.1002/cyto.a.23601⟩

Article dans une revue hal-03161874v2
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Kernel machine score test for pathway analysis in the presence of semi-competing risks

Matey Neykov , Boris P. Hejblum , Jennifer A Sinnott

Statistical Methods in Medical Research, 2018, Statistical Methods in Medical Research, 27 (4), pp.1099-1114. ⟨10.1177/0962280216653427⟩

Article dans une revue hal-01395970v1
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Variance component score test for time-course gene set analysis of longitudinal RNA-seq data

Denis Agniel , Boris P. Hejblum

Biostatistics, 2017, Biostatistics, 18 (4), pp.589-604. ⟨10.1093/biostatistics/kxx005⟩

Article dans une revue hal-01579077v1
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Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV

Anne Rechtien , Laura Richert , Hadrien Lorenzo , Gloria Martrus , Boris P. Hejblum et al.

Cell Reports, 2017, 20 (9), pp.2251 - 2261. ⟨10.1016/j.celrep.2017.08.023⟩

Article dans une revue hal-01579246v1
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Phenome-Wide Association Study of Autoantibodies to Citrullinated and Noncitrullinated Epitopes in Rheumatoid Arthritis

Katherine P. Liao , Jeffrey A Sparks , Boris P. Hejblum , I-Hsin Kuo , Jing Cui et al.

Arthritis & rheumatology, 2017, 69 (4), pp.742 - 749. ⟨10.1002/art.39974⟩

Article dans une revue hal-01654405v1

Group and sparse group partial least square approaches applied in genomics context

Benoit Liquet , Pierre Lafaye de Micheaux , Boris P. Hejblum , Rodolphe Thiébaut

Bioinformatics, 2016, 32 (1), pp.35-42. ⟨10.1093/bioinformatics/btv535⟩

Article dans une revue hal-01288891v1
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Time-Course Gene Set Analysis for Longitudinal Gene Expression Data

Boris P. Hejblum , Jason Skinner , Rodolphe Thiébaut

PLoS Computational Biology, 2015, 11 (6), pp.e1004310. ⟨10.1371/journal.pcbi.1004310⟩

Article dans une revue hal-01203446v1

L’analyse des « Big Data » en recherche clinique

Rodolphe Thiébaut , Boris P. Hejblum , Laura Richert

Epidemiology and Public Health = Revue d'Epidémiologie et de Santé Publique, 2014, 62 (1), pp.1-4. ⟨10.1016/j.respe.2013.12.021⟩

Article dans une revue inserm-00933691v1

Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination.

David Furman , Boris P. Hejblum , Noah Simon , Vladimir Jojic , Cornelia L. Dekker et al.

Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (2), pp.869-74. ⟨10.1073/pnas.1321060111⟩

Article dans une revue inserm-00933693v1
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Evidence synthesis through a degradation model applied to myocardial infarction.

Daniel Commenges , Boris P. Hejblum

Lifetime Data Analysis, 2013, 19 (1), pp.1-18. ⟨10.1007/s10985-012-9227-3⟩

Article dans une revue inserm-00726036v1
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Reservoir Computing for Short High-Dimensional Time Series: an Application to SARS-CoV-2 Hospitalization Forecast

Thomas Ferté , Dan Dutartre , Boris P. Hejblum , Romain Griffier , Vianney Jouhet et al.

ICML'24: Proceedings of the 41st International Conference on Machine Learning, Jul 2024, Vienna, Austria. pp.13570--13591, ⟨10.5555/3692070⟩

Communication dans un congrès hal-04693930v1
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Optimizing Reservoir Computing with Genetic Algorithm for High-Dimensional SARS-CoV-2 Hospitalization Forecasting: Impacts of Genetic Algorithm Hyperparameters on Feature Selection and Reservoir Computing Hyperparameter Tuning

Thomas Ferté , Dan Dutartre , Boris P. Hejblum , Romain Griffier , Vianney Jouhet et al.

EA 2024 - 16th International Conference Artificial Evolution, Pierrick Legrand, Oct 2024, Bordeaux, France

Communication dans un congrès hal-04905975v1
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Méthodes pour l'inférence post-clustering appliquées à l'expression génique

Benjamin Hivert , Denis Agniel , Rodolphe Thiébaut , Boris P. Hejblum

SFDS 2022 - Journées de Statistique de la SFdS, Jun 2022, Lyon, France

Communication dans un congrès hal-03906534v1

Untargeted metabolomics in a prospective cohort to identify diet-related metabolites associated with age-related cognitive decline

Sophie Lefèvre-Arbogast , Dorrain Y. Low , Raúl González-Domínguez , Mireia Urpi-Sarda , Pierre Micheau et al.

Alzheimer’s Association International Conference, Jul 2019, Los Angeles, United States

Communication dans un congrès hal-04796946v1

Untargeted metabolomics in a prospective cohort to identify diet-related metabolites associated with age-related cognitive decline

Dorrain Y. Low , Sophie Lefèvre-Arbogast , Raúl González-Domínguez , Mireia Urpi-Sarda , Pierre Micheau et al.

15th annual conference of the metabolomics society. Metabolomics 2019, Jun 2019, La Hague, Netherlands

Communication dans un congrès hal-04796907v1

Untargeted profiling of serum samples revealed diet-related metabolites associated with subsequent cognitive decline in the 3-City cohort

Dorrain Y. Low , Sophie Lefèvre-Arbogast , Raúl González-Domínguez , Mireia Urpi-Sarda , Pierre Micheau et al.

13th European Nutrition Conference FENS 2019, Oct 2019, Dublin, Ireland

Poster de conférence hal-04823822v1

Identification of a circulating biomarker highly associated to retinal omega-3 polyunsaturated fatty acid content: the BLISAR project

Niyazi Acar , Soufiane Ajana , Olivier Berdeaux , Hélène Jacqmin-Gadda , Boris Hejblum et al.

Annual meeting of the association for research in vision and ophthalmology (ARVO), Apr 2019, Vancouver, Canada, United States. Association for Research in Vision and Ophthalmology, Investigative Ophthalmology and Visual Science, 60 (9), 1 p., 2019

Poster de conférence hal-02737963v1

Association of a predictor of retinal omega-3 polyunsaturated fatty acids with advanced age-related macular degeneration: the BLISAR project

Cécile Delcourt , Soufiane Ajana , Bénédicte Merle , Hélène Jacqmin-Gadda , Boris P. Hejblum et al.

Annual meeting of the association-for-research-in-vision-and-ophthalmology (ARVO), Apr 2019, Vancouver, Canada, United States. Association for Research in Vision and Ophthalmology, Investigative Ophthalmology and Visual Science, 60 (9), 1 p., 2019

Poster de conférence hal-02736092v1
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Identification of dietary modulators of cognitive function in ageing using metabolomics discovery

Dorrain Low Yanwen , Sophie Lefèvre-Arbogast , Mélanie Pétéra , Pierre Micheau , Delphine Centeno et al.

Journée Scientifique du CRNH Auvergne, Nov 2017, Clermont-Ferrand, Canada. 2017, Journée Scientifique du CRNH Auvergne 2017

Poster de conférence hal-01644048v1

Identification of dietary modulators of cognitive function in ageing using metabolomics discovery

Dorrain Low Yanwen , Sophie Lefèvre-Arbogast , Mélanie Pétéra , Pierre Micheau , Delphine Centeno et al.

8. International Conference on Polyphenols and Health ICPH 2017, Oct 2017, Québec, Canada. 2017

Poster de conférence hal-01595015v1
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Vers une recherche reproductible

Loic Desquilbet , Sabrina Granger , Boris Hejblum , Arnaud Legrand , Pascal Pernot et al.

Unité régionale de formation à l'information scientifique et technique de Bordeaux. Unité régionale de formation à l'information scientifique et technique de Bordeaux, pp.1-161, 2019, 979-10-97595-05-0

Ouvrages hal-02144142v3
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Adaptive Dirichlet Process mixture model with unknown concentration parameter and variance: Scaling high dimensional clustering via collapsed variational inference

Annesh Pal , Aguirre Mimoun , Rodolphe Thiébaut , Boris P. Hejblum

2026

Pré-publication, Document de travail hal-05490235v1

Representation Learning to Advance Multi-institutional Studies with Electronic Health Record Data

Doudou Zhou , Han Tong , Linshanshan Wang , Suqi Liu , Xin Xiong et al.

2025

Pré-publication, Document de travail hal-05222545v1
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Epidemic Forecasting: Lessons Learned from the SARS-CoV-2 Pandemic to Balance Accuracy, Feasibility, and Impact

Thomas Ferté , Vincent Thevenet , Xavier Hinaut , Pierrick Legrand , Dan Dutartre et al.

2025

Pré-publication, Document de travail hal-05392781v1

Practical limitations for real-life application of data fission and data thinning in post-clustering differential analysis

Benjamin Hivert , Denis Agniel , Rodolphe Thiébaut , Boris P. Hejblum

2024

Pré-publication, Document de travail hal-04745517v1

Distribution-free complex hypothesis testing for single-cell RNA-seq differential expression analysis

Marine Gauthier , Denis Agniel , Rodolphe Thiébaut , Boris P. Hejblum

2021

Pré-publication, Document de travail hal-03478097v1

Gene Set Analysis for time-to-event outcome with the Generalized Berk–Jones statistic

Laura Villain , Thomas Ferté , Rodolphe Thiébaut , Boris P. Hejblum

2021

Pré-publication, Document de travail hal-03478102v1
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Realistic and Robust Reproducible Research for Biostatistics

Boris P. Hejblum , Kevin Kunzmann , Ennio Lavagnini , Anna Hutchinson , David Robertson et al.

2020

Pré-publication, Document de travail hal-03100421v1
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Population modeling of early COVID-19 epidemic dynamics in French regions and estimation of the lockdown impact on infection rate

Mélanie Prague , Linda Wittkop , Quentin Clairon , Dan Dutartre , Rodolphe Thiébaut et al.

2020

Pré-publication, Document de travail hal-02555100v1