Brigitte Kerfelec

Identifiants chercheurs

IdHAL :

brigitte-kerfelec

ORCID :

0000-0001-8423-3423

Publications

Article dans une revue (27)

Mesothelin biology and the evolving landscape of targeted immunotherapy Remy Boisgard,Patrick Chames,Brigitte Kerfelec Molecular Therapy: Oncology, 2026, 34 (1), pp.201148. ⟨10.1016/j.omton.2026.201148⟩ Article dans une revue hal-05530530v1
Nanobody-enhanced T cell cancer immunotherapy: Advancing precision medicine Remy Boisgard,Juliette Prothon,Celia Torrielli,Patrick Chames,Brigitte Kerfelec Molecular Therapy, 2025, Online ahead of print. ⟨10.1016/j.ymthe.2025.10.043⟩ Article dans une revue hal-05363771v1
Novel single-domain antibodies targeting a unique transferrin receptor 1 epitope for cross-species delivery of drugs in the central nervous system Marion David,Romy Cohen,Diane Beuzelin,Géraldine Ferracci,Marina Cresciet al. Journal of Controlled Release, 2025, 388, pp.114344. ⟨10.1016/j.jconrel.2025.114344⟩ Article dans une revue hal-05340484v1
Decoupling individual host response and immune cell engager cytotoxic potency Cristina Gonzalez Gutierrez,Adrien Aimard,Martine Biarnes-Pélicot,Brigitte Kerfelec,Pierre-Henri Puechet al. ACS Nano, 2025, 19 (2), pp.2089-2098. ⟨10.1021/acsnano.4c08541⟩ Article dans une revue hal-04778416v1
Functional targeting of Glypican-4 by a conformation-specific single-domain antibody Remi Bonjean,Rossana Cuciniello,Brigitte Kerfelec,Patrick Chames,Rosanna Dono Biomaterials, 2025, 328, pp.123864. ⟨10.1016/j.biomaterials.2025.123864⟩ Article dans une revue hal-05409215v1
Rapid nanobody-based imaging of mesothelin expressing malignancies compatible with blocking therapeutic antibodies Abdennour Benloucif,Damien Meyer,Laure Balasse,Armelle Goubard,Lucile Danneret al. Frontiers in Immunology, 2023, 14, pp.1200652. ⟨10.3389/fimmu.2023.1200652⟩ Article dans une revue hal-04259727v1
Anti-NKG2D single domain-based antibodies for the modulation of anti-tumor immune response Adeline Raynaud,Klervi Desrumeaux,Laurent Vidard,Elise Termine,Daniel Batyet al. OncoImmunology, 2020, 10, ⟨10.1080/2162402x.2020.1854529⟩ Article dans une revue hal-03371613v1
A Bispecific Antibody-Based Approach for Targeting Mesothelin in Triple Negative Breast Cancer Joanie del Bano,Rémy Florès-Florès,Emmanuelle Josselin,Armelle Goubard,Laëtitia Ganieret al. Frontiers in Immunology, 2019, 10, pp.1593. ⟨10.3389/fimmu.2019.01593⟩ Article dans une revue hal-02520930v1
Nanobody-CD16 Catch Bond Reveals NK Cell Mechanosensitivity Cristina González,Patrick Chames,Brigitte Kerfelec,Daniel Baty,Philippe Robertet al. Biophysical Journal, 2019, 116 (8), pp.1516-1526. ⟨10.1016/j.bpj.2019.03.012⟩ Article dans une revue hal-02323625v1
Preclinical Evaluation of Mesothelin-Specific Ligands for SPECT Imaging of Triple-Negative Breast Cancer Christopher Montemagno,Sandrine Bacot,Mitra Ahmadi,Brigitte Kerfelec,Daniel Batyet al. Journal of Nuclear Medicine, 2018, 59 (7), pp.1056-1062. ⟨10.2967/jnumed.117.203489⟩ Article dans une revue hal-02115385v1
Taking up Cancer Immunotherapy Challenges: Bispecific Antibodies, the Path Forward? Joanie del Bano,Patrick Chames,Daniel Baty,Brigitte Kerfelec Antibodies, 2016, 5 (1), ⟨10.3390/antib5010001⟩ Article dans une revue hal-01450799v1
Anti-Mesothelin Nanobodies for Both Conventional and Nanoparticle-Based Biomedical Applications. Andrew M Prantner,Marc Turini,Brigitte Kerfelec,Shree Joshi,Daniel Batyet al. Journal of Biomedical Nanotechnology, 2015, pp.1201-12 Article dans une revue hal-01450786v1
Masked Selection: A Straightforward and Flexible Approach for the Selection of Binders Against Specific Epitopes and Differentially Expressed Proteins by Phage Display Klervi Even-Desrumeaux,Damien Nevoltris,Marie Noelle Lavaut,Karima Alim,Jean-Paul Borget al. Molecular and Cellular Proteomics, 2014, 13 (2), pp.653-665. ⟨10.1074/mcp.O112.025486⟩ Article dans une revue hal-02115444v1
A FcγRIII-engaging bispecific antibody expands the range of HER2-expressing breast tumors eligible to antibody therapy Marc Turini,Patrick Chames,Pierre Bruhns,Daniel Baty,Brigitte Kerfelec Oncotarget, 2014, 5 (14), ⟨10.18632/oncotarget.2093⟩ Article dans une revue hal-02115462v1
Single-Domain Antibody-Based and Linker-Free Bispecific Antibodies Targeting Fc RIII Induce Potent Antitumor Activity without Recruiting Regulatory T Cells C. Rozan,A. Cornillon,C. Petiard,M. Chartier,G. Beharet al. Molecular Cancer Therapeutics, 2013, 12 (8), pp.1481-1491. ⟨10.1158/1535-7163.MCT-12-1012⟩ Article dans une revue hal-02115468v1
Single-domain antibody-based and linker-free bispecific antibodies targeting FcγRIII induce potent antitumor activity without recruiting regulatory T cells. Caroline Rozan,Amélie Cornillon,Corinne Petiard,M. Chartier,G. Beharet al. Molecular Cancer Therapeutics, 2013, 12 (8), pp.1481-1491. ⟨10.1158/1535-7163.MCT-12-1012⟩ Article dans une revue hal-02454959v1
Therapeutic antibodies for the treatment of pancreatic cancer. Patrick Chames,Brigitte Kerfelec,Daniel Baty TheScientificWorldJournal, 2010, 10, pp.1107-20. ⟨10.1100/tsw.2010.103⟩ Article dans une revue inserm-00497886v1
Therapeutic Antibodies for the Treatment of Pancreatic Cancer Patrick Chames,Brigitte Kerfelec,Daniel Baty The Scientific World Journal, 2010, 10, pp.1107-1120. ⟨10.1100/tsw.2010.103⟩ Article dans une revue hal-02115485v1
Modification of pancreatic lipase properties by directed molecular evolution D. Colin,P. Deprez-Beauclair,N. Silva,L. Infantes,B. Kerfelec Protein Engineering, Design and Selection, 2010, 23 (5), pp.365-373. ⟨10.1093/protein/gzq008⟩ Article dans une revue hal-02115590v1
Exploring the active site cavity of human pancreatic lipase Damien Colin,Paule Deprez-Beauclair,Maya Allouche,Robert Brasseur,Brigitte Kerfelec Biochemical and Biophysical Research Communications, 2008, 370 (3), pp.394-398. ⟨10.1016/j.bbrc.2008.03.043⟩ Article dans une revue istex hal-02657739v1
Structure and orientation of pancreatic colipase in a lipid environment: PM-IRRAS and Brewster Angle Microscopy studies Maya Allouche,Sabine Castano,Damien Colin,Bernard Desbat,Brigitte Kerfelec Biochemistry, 2007, 46 (51), pp.15188-15197. ⟨10.1021/bi701831f⟩ Article dans une revue istex hal-02669029v1
Interactions of bile salt micelles and colipase studied through intermolecular nOes Cyril Dominguez,Corinne Sebban-Kreuzer,Olivier Bornet,Brigitte Kerfelec,Catherine Chapuset al. FEBS Letters, 2000, 482 (1-2), pp.109-112. ⟨10.1016/s0014-5793(00)02034-2⟩ Article dans une revue hal-05506840v1
Crystal structure of bovine procarboxypeptidase A-S6 subunit III, a highly structured truncated zymogen E D. Pignol,C. Gaboriaud,Thierry Michon,Brigitte Kerfelec,Catherine Chapuset al. EMBO Journal, 1994, 13 (8), pp.1763-1771 Article dans une revue hal-02704224v1
Secretion of pancreatic procarboxypeptidase A in the Camelidae : an indication for the adaptation to the rumination Thierry Michon,Brigitte Kerfelec,Catherine Chapus Protein Sequences and Data Analysis, 1993, 5, pp.263-267 Article dans une revue hal-02704459v1
Microcalorimetric investigation of the interactions between the subunits of the bovine pancreatic procarboxypeptidase A-S6 complex Thierry Michon,J.C. Sari,Simone Granon,Brigitte Kerfelec,Catherine Chapus European Journal of Biochemistry, 1991, 201, pp.217-222 Article dans une revue hal-02703968v1
Further studies on the human pancreatic binary complexes involving procarboxypeptidase A M. Moulard,Thierry Michon,Brigitte Kerfelec,Catherine Chapus FEBS Letters, 1990, 261 (1), pp.179-183 Article dans une revue hal-02709529v1
Le complexe ternaire de la procarboxypeptidase A du pancréas de bœuf B. Kerfelec,C. Chapus,A. Puigserver Reproduction Nutrition Développement, 1986, 26 (5B), pp.1209-1209 Article dans une revue hal-00898546v1