Bruno Senger

Publications

Article dans une revue (34)

A systematic bi-genomic split-GFP assay illuminates the mitochondrial matrix proteome and protein targeting routes Yury Bykov,Solène Zuttion,Bruno Senger,Ofir Klein,Yeynit Asrafet al. eLife, 2025, ⟨10.7554/eLife.98889.1⟩ Article dans une revue hal-04753356v1
Oligomer-based functions of mitochondrial porin Hironori Takeda,Saori Shinoda,Chiho Goto,Akihisa Tsutsumi,Haruka Sakaueet al. Nature Communications, 2025, 16 (1), pp.6854. ⟨10.1038/s41467-025-62021-4⟩ Article dans une revue hal-05234652v1
Monitoring mitochondrial localization of dual localized proteins using a Bi-Genomic Mitochondrial-Split-GFP Solène Zuttion,Bruno Senger,Chiranjit Panja,Sylvie Friant,Róża Kucharczyket al. Methods in Enzymology, 2024, Methods in Enzymology, 706, pp.75-95. ⟨10.1016/bs.mie.2024.07.028⟩ Article dans une revue hal-05141285v1
Loss of seryl-tRNA synthetase ( SARS1 ) causes complex spastic paraplegia and cellular senescence Edgard Verdura,Bruno Senger,Miquel Raspall-Chaure,Agatha Schlüter,Nathalie Launayet al. Journal of Medical Genetics, 2022, pp.jmedgenet-2022-108529. ⟨10.1136/jmg-2022-108529⟩ Article dans une revue hal-03798206v1
tRNA-dependent addition of amino acids to cell wall and membrane components Guillaume Grob,Marine Hemmerle,Nathaniel Yakobov,Nassira Mahmoudi,Frédéric Fischeret al. Biochimie, 2022, 203, pp.93-105. ⟨10.1016/j.biochi.2022.09.017⟩ Article dans une revue (article de synthèse) hal-04235462v1
RNA-dependent synthesis of ergosteryl-3β-O-glycine in Ascomycota expands the diversity of steryl-amino acids Nathaniel Yakobov,Nassira Mahmoudi,Guillaume Grob,Daisuke Yokokawa,Yusuke Sagaet al. Journal of Biological Chemistry, 2022, 298 (3), pp.101657. ⟨10.1016/j.jbc.2022.101657⟩ Article dans une revue hal-03796231v1
Bi-Genomic Mitochondrial-Split-GFP − the Yeast System for Screening the Mitochondrial Matrix Echoforms of Dually Localized Proteins Gaëtan Bader,Ludovic Enkler,Yuhei Araiso,Marine Hemmerle,Krystyna Bińkoet al. Biochimica biophysica acta (BBA) - Bioenergetics, 2022, 1863, pp.148895. ⟨10.1016/j.bbabio.2022.148895⟩ Article dans une revue hal-04833277v1
Cex1 is a component of the COPI intracellular trafficking machinery Ludovic Enkler,Bruno Rinaldi,J.O. de Craene,Philippe Hammann,Osamu Nurekiet al. Biology Open, 2021, 10 (3), pp.bio058528. ⟨10.1242/bio.058528⟩ Article dans une revue hal-03288818v1
Assigning mitochondrial localization of dual localized proteins using a yeast Bi-Genomic Mitochondrial-Split-GFP Gaétan Bader,Ludovic Enkler,Yuhei Araiso,Marine Hemmerle,Krystyna Binkoet al. eLife, 2020, 9, pp.e56649. ⟨10.7554/eLife.56649⟩ Article dans une revue hal-02898815v1
RNA-dependent sterol aspartylation in fungi Nathaniel Yakobov,Frédéric Fischer,Nassira Mahmoudi,Yusuke Saga,Christopher D Grubeet al. Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (26), pp.14948-14957. ⟨10.1073/pnas.2003266117⟩ Article dans une revue pasteur-02869570v1
De Novo and Bi-allelic Pathogenic Variants in NARS1 Cause Neurodevelopmental Delay Due to Toxic Gain-of-Function and Partial Loss-of-Function Effects Andreea Manole,Stephanie Efthymiou,Emer O'Connor,Marisa I Mendes,Matthew Jenningset al. American Journal of Human Genetics, 2020, 107 (2), pp.311-324. ⟨10.1016/j.ajhg.2020.06.016⟩ Article dans une revue hal-02992472v1
Cytosolic aminoacyl-tRNA synthetases: Unanticipated relocations for unexpected functions Nathaniel Yakobov,Sylvain Debard,Frédéric Fischer,Bruno Senger,Hubert Dominique Becker Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2018, 1861 (4), pp.387-400. ⟨10.1016/j.bbagrm.2017.11.004⟩ Article dans une revue hal-02370188v1
Cex1 is a new component of the COPIb trans-Golgi-to-vacuole intracellular trafficking machinery Ludovic Enkler,J.O. de Craene,Bruno Rinaldi,Philippe Hammann,Osamu Nurekiet al. BioRxiv, 2018 Article dans une revue hal-02918644v1
Nonconventional localizations of cytosolic aminoacyl-tRNA synthetases in yeast and human cells Sylvain Debard,Gaétan Bader,Johan-Owen de Craene,Ludovic Enkler,Séverine Bäret al. Methods, 2017, 113, pp.91 - 104. ⟨10.1016/j.ymeth.2016.09.017⟩ Article dans une revue hal-01771885v1
Expression of Nuclear and Mitochondrial Genes Encoding ATP Synthase Is Synchronized by Disassembly of a Multisynthetase Complex Mathieu Frechin,Ludovic Enkler,Emmanuel Tetaud,Daphné Laporte,Bruno Sengeret al. Molecular Cell, 2014, 56 (6), pp.763-776. ⟨10.1016/j.molcel.2014.10.015⟩ Article dans une revue hal-02370180v1
Exploring the evolutionary diversity and assembly modes of multi-aminoacyl-tRNA synthetase complexes: Lessons from unicellular organisms Daphné Laporte,Jonathan Huot,Gaétan Bader,Ludovic Enkler,Bruno Sengeret al. FEBS Letters, 2014, 588 (23), pp.4268-4278. ⟨10.1016/j.febslet.2014.10.007⟩ Article dans une revue hal-02370182v1
Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases Yuhei Araiso,Jonathan Huot,Takuya Sekiguchi,Mathieu Frechin,Frédéric Fischeret al. Nucleic Acids Research, 2014, 42 (9), pp.6052-6063. ⟨10.1093/nar/gku234⟩ Article dans une revue hal-02370178v1
Crystal structure of Cex1p reveals the mechanism of tRNA trafficking between nucleus and cytoplasm Kayo Nozawa,Ryuichiro Ishitani,Tohru Yoshihisa,Mamoru Sato,Fumio Arisakaet al. Nucleic Acids Research, 2013, 41 (6), pp.3901-3914. ⟨10.1093/nar/gkt010⟩ Article dans une revue hal-02370174v1
Arc1p: anchoring, routing, coordinating. Mathieu Frechin,Daniel Kern,Robert Pierre Martin,Hubert Becker,Bruno Senger FEBS Letters, 2010, 584 (2), pp.427-33. ⟨10.1016/j.febslet.2009.11.037⟩ Article dans une revue istex hal-00451322v1
Yeast mitochondrial Gln-tRNA(Gln) is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS. Mathieu Fréchin,Bruno Senger,Melanie Brayé,Daniel Kern,Robert Pierre Martinet al. Genes and Development, 2009, 23 (9), pp.1119-1130. ⟨10.1101/gad.518109⟩ Article dans une revue hal-00484960v1
Role of Arc1p in the Modulation of Yeast Glutamyl-tRNA Synthetase Activity † Jean-Sébastien Graindorge,Bruno Senger,Denis Tritch,George Simos,Franco Fasiolo Biochemistry, 2005, 44 (4), pp.1344-1352. ⟨10.1021/bi049024z⟩ Article dans une revue istex hal-02370163v1
Deletion of EFL1 Results in Heterogeneity of the 60S GTPase-associated rRNA Conformation Jean-Sébastien Graindorge,Jean-Claude Rousselle,Bruno Senger,Pascal Lenormand,Abdelkader Namaneet al. Journal of Molecular Biology, 2005, 352 (2), pp.355-369. ⟨10.1016/j.jmb.2005.07.037⟩ Article dans une revue istex hal-02370162v1
Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes Edith Bogengruber,Peter Briza,Edith Doppler,Herbert Wimmer,Lore Kolleret al. FEMS Yeast Research, 2003, 3 (1), pp.35-43. ⟨10.1111/j.1567-1364.2003.tb00136.x⟩ Article dans une revue hal-02370150v1
Ribosome assembly in eukaryotes Micheline Fromont-Racine,Bruno Senger,Cosmin Saveanu,Franco Fasiolo Gene, 2003, 313, pp.17 - 42. ⟨10.1016/S0378-1119(03)00629-2⟩ Article dans une revue istex pasteur-01404699v1
The Nucle(ol)ar Tif6p and Efl1p Are Required for a Late Cytoplasmic Step of Ribosome Synthesis Bruno Senger,Denis L.J. Lafontaine,Jean-Sebastien Graindorge,Olivier Gadal,Alain Camasseset al. Molecular Cell, 2001, 8 (6), pp.1363-1373. ⟨10.1016/s1097-2765(01)00403-8⟩ Article dans une revue hal-02370147v1
Yeast cytoplasmic and mitochondrial methionyl-tRNA synthetases: two structural frameworks for identical functions Bruno Senger,Laurence Despons,Philippe Walter,Hieronim Jakubowski,Franco Fasiolo Journal of Molecular Biology, 2001, 311 (1), pp.205-216. ⟨10.1006/jmbi.2001.4844⟩ Article dans une revue istex hal-02370141v1
Mtr10p functions as a nuclear import receptor for the mRNA-binding protein Npl3p B. Senger EMBO Journal, 1998, 17 (8), pp.2196-2207. ⟨10.1093/emboj/17.8.2196⟩ Article dans une revue hal-02370138v1
The Modified Wobble Base Inosine in Yeast tRNA Ile Is a Positive Determinant for Aminoacylation by Isoleucyl-tRNA Synthetase † Bruno Senger,Sylvie Auxilien,Uwe Englisch,Friedrich Cramer,Franco Fasiolo Biochemistry, 1997, 36 (27), pp.8269-8275. ⟨10.1021/bi970206l⟩ Article dans une revue istex hal-02370118v1
Conservation in Evolution for a Small Monomeric Phenylalanyl-tRNA Synthetase of the tRNA Phe Recognition Nucleotides and Initial Aminoacylation Site † Ruslan Aphasizhev,Bruno Senger,Jens-Uwe Rengers,Mathias Sprinzl,Philippe Walteret al. Biochemistry, 1996, 35 (1), pp.117-123. ⟨10.1021/bi9517998⟩ Article dans une revue istex hal-02369829v1
The Presence of a D-Stem but not a T-Stem is Essential for Triggering Aminoacylation upon Anticodon Binding in Yeast Methionine tRNA Bruno Senger,Ruslan Aphasizhev,Philippe Walter,Franco Fasiolo Journal of Molecular Biology, 1995, 249 (1), pp.45-58. ⟨10.1006/jmbi.1995.0279⟩ Article dans une revue istex hal-02370102v1
Modulation of the Suppression Efficiency and Amino Acid Identity of an Artificial Yeast Amber Isoleucine Transfer RNA in Escherichia coli by a G-U Pair in the Anticodon Stem V. Buttcher,B. Senger,S. Schumacher,J. Reinbolt,F. Fasiolo Biochemical and Biophysical Research Communications, 1994, 200 (1), pp.370-377. ⟨10.1006/bbrc.1994.1458⟩ Article dans une revue istex hal-02369873v1
The anticodon triplet is not sufficient to confer methionine acceptance to a transfer RNA. B. Senger,L. Despons,P. Walter,F. Fasiolo Proceedings of the National Academy of Sciences of the United States of America, 1992, 89 (22), pp.10768-10771. ⟨10.1073/pnas.89.22.10768⟩ Article dans une revue hal-02369845v1
Binding of the yeast tRNAMet anticodon by the cognate methionyl-tRNA synthetase involves at least two independent peptide regions Laurence Despons,Bruno Senger,Franco Fasiolo,Philippe Walter Journal of Molecular Biology, 1992, 225 (3), pp.897-907. ⟨10.1016/0022-2836(92)90409-d⟩ Article dans une revue istex hal-02369843v1
Identification of potential amino acid residues supporting anticodon recognition in yeast methionyl-tRNA synthetase Laurence Despons,Philippe Walter,Bruno Senger,Jean-Pierre Ebel,Franco Fasiolo FEBS Letters, 1991, 289 (2), pp.217-220. ⟨10.1016/0014-5793(91)81073-h⟩ Article dans une revue hal-02369841v1

Chapitre d'ouvrage (2)

Visualizing Mitochondrial Importability of a Protein Using the Yeast Bi-Genomic Mitochondrial-Split-GFP Strain and an Ordinary Fluorescence Microscope Marine Hemmerle,Bruno Senger,Roza Kucharczyk,Hubert Becker Mitochondria, 2497, Springer US, pp.255-267, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2309-1_16⟩ Chapitre d'ouvrage hal-03798229v1
Non-canonical inputs and outputs of tRNA aminoacylation Marine Hemmerle,Marion Wendenbaum,Guillaume Grob,Nathaniel Yakobov,Nassira Mahmoudi-Kaidiet al. The Enzymes, 48, , 2020, Biology of Aminoacyl-tRNA Synthetases, ⟨10.1016/bs.enz.2020.04.003⟩ Chapitre d'ouvrage hal-02919274v1

HDR (1)

Etude de nouveaux aspects liés à la machinerie traductionnelle : amidotransférases et aminoacyl-ARNt synthétases. Bruno Senger Sciences du Vivant [q-bio]. Université Louis Pasteur - Strasbourg I, 2006 HDR tel-00270801v1