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Carlo Petosa

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Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet

Domenico Iuso , Isabel Garcia-Saez , Yohann Couté , Yoshiki Yamaryo-Botté , Elisabetta Boeri Erba
Science Advances , 2023, 9 (36), pp.eadh0140. ⟨10.1126/sciadv.adh0140⟩
Journal articles hal-04216158v1
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Binding stoichiometry and structural model of the HIV-1 Rev/Importin β complex

Didier Spittler , Rose-Laure Indorato , Elisabetta Boeri Erba , Elise Delaforge , Luca Signor
Life Science Alliance, 2022, ⟨10.26508/lsa.202201431⟩
Journal articles hal-03453423v2

Structural basis of DNA methylation-dependent site selectivity of the Epstein–Barr virus lytic switch protein ZEBRA/Zta/BZLF1

Florent Bernaudat , Montse Gustems , Johannes Günther , Mizar Oliva , Alexander Buschle
Nucleic Acids Research, 2022, ⟨10.1093/nar/gkab1183⟩
Journal articles hal-03518161v1
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Enantioselective approach for expanding the three‐dimensional space of tetrahydroquinoline to develop bet bromodomain inhibitors

Marie‐ange Lespinasse , Kaiyao Wei , Justine Perrin , Matthias Winkler , Sieme Hamaidia
Chemistry - A European Journal, 2022, 2022, pp.e202202293. ⟨10.1002/chem.202202293⟩
Journal articles hal-03806738v1
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Toward more potent imidazopyridine inhibitors of Candida albicans Bdf1: Modeling the role of structural waters in selective ligand binding

Yingsheng Zhou , Justin Overhulse , Nathan Dupper , Yanchun Guo , Boris Kashemirov
Journal of Computational Chemistry, 2022, 43, pp.2121-2130. ⟨10.1002/jcc.26997⟩
Journal articles hal-03806660v1
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ATAD2 controls chromatin-bound HIRA turnover

Tao Wang , Daniel Perazza , Fayçal Boussouar , Matteo Cattaneo , Alexandre Bougdour
Life Science Alliance, 2021, ⟨10.26508/lsa.202101151⟩
Journal articles hal-03359419v1
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Cryo-electron microscopy of the chromatin fiber

Ramachandran Boopathi , Stefan Dimitrov , Ali Hamiche , Carlo Petosa , Jan Bednar
Current Opinion in Structural Biology, 2020, 64, pp.97-103. ⟨10.1016/j.sbi.2020.06.016⟩
Journal articles hal-02947617v1
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Exploring the structure and dynamics of macromolecular complexes by native mass spectrometry

Elisabetta Boeri Erba , Luca Signor , Carlo Petosa
Journal of Proteomics, 2020, 222, pp.103799. ⟨10.1016/j.jprot.2020.103799⟩
Journal articles hal-02864550v1
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Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends

Ramachandran Boopathi , Radostin Danev , Maryam Khoshouei , Seyit Kale , Sunil Nahata
Nucleic Acids Research, 2020, 48 (10), pp.5735-5748. ⟨10.1093/nar/gkaa246⟩
Journal articles hal-03007422v1
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Phosphomimetic mutations modulate the ability of HIV-1 Rev to bind human Importin β in vitro

Nadia Ben Fadhel , Luca Signor , Carlo Petosa , Marjolaine Noirclerc-Savoye
Journal articles hal-02270755v1

Characterizing Intact Macromolecular Complexes Using Native Mass Spectrometry.

Elisabetta Boeri Erba , Luca Signor , Mizar Francesca Oliva , Fabienne Hans , Carlo Petosa
Methods in Molecular Biology, 2018, 1764, pp.133-151. ⟨10.1007/978-1-4939-7759-8_9⟩
Journal articles hal-01807803v1

A new hope to fight invasive fungal infection

Carlo Petosa , Jérôme Govin , Flore Mietton
Médecine/Sciences, 2018, 34 (2), pp.123 - 125. ⟨10.1051/medsci/20183402007⟩
Journal articles hal-01726209v1

Structure of an H1-Bound 6-Nucleosome Array Reveals an Untwisted Two-Start Chromatin Fiber Conformation

Isabel Garcia-Saez , Hervé Menoni , Ramachandran Boopathi , Manu Shukla , Lama Soueidan
Molecular Cell, 2018, 72 (5), pp.902-915.e7. ⟨10.1016/j.molcel.2018.09.027⟩
Journal articles hal-02393274v1

Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.

Jan Bednar , Isabel Garcia-Saez , Ramachandran Boopathi , Amber R Cutter , Gabor Papai
Molecular Cell, 2017, 66 (5), pp.729. ⟨10.1016/j.molcel.2017.05.018⟩
Journal articles hal-01537811v1
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Selective BET bromodomain inhibition as an antifungal therapeutic strategy.

Flore Mietton , Elena Ferri , Morgane Champleboux , Ninon Zala , Danièle Maubon
Nature Communications, 2017, 8, pp.15482. ⟨10.1038/ncomms15482⟩
Journal articles hal-01537809v1

Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells

Yuichi Morozumi , Fayçal Boussouar , Minjia Tan , Apirat Chaikuad , Mahya Jamshidikia
Journal of molecular cell biology, 2016, 8 (4), pp.349 - 362. ⟨10.1093/jmcb/mjv060⟩
Journal articles hal-01415782v1

Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein

Francesca Coscia , Leandro F Estrozi , Fabienne Hans , Hélène Malet , Marjolaine Noirclerc-Savoye
Scientific Reports, 2016, 6, pp.30909. ⟨10.1038/srep30909⟩
Journal articles hal-01396217v1

Data publication with the structural biology data grid supports live analysis

Peter A. Meyer , Stephanie Socias , Jason Key , Elizabeth Ransey , Emily C. Tjon
Nature Communications, 2016, 7, ⟨10.1038/ncomms10882⟩
Journal articles hal-01299025v1

Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters.

Afsaneh Goudarzi , Di Zhang , He Huang , Sophie Barral , Oh Kwang Kwon
Molecular Cell, 2016, 62 (2), pp.169-80. ⟨10.1016/j.molcel.2016.03.014⟩
Journal articles hal-01341099v1

Bromodomains: Structure, function and pharmacology of inhibition.

Elena Ferri , Carlo Petosa , Charles E Mckenna
Biochemical Pharmacology, 2016, 106, pp.1-18
Journal articles hal-01256715v1

The emerging role of native mass spectrometry in characterizing the structure and dynamics of macromolecular complexes

Elisabetta Boeri Erba , Carlo Petosa
Protein Science, 2015, 10.1002, pro.2661. ⟨10.1002/pro.2661⟩
Journal articles hal-01164101v1

Structure of a truncation mutant of the nuclear export factor CRM1 provides insights into the auto-inhibitory role of its C-terminal helix.

Cyril Dian , Florent Bernaudat , Karla Langer , Mizar Francesca Oliva , Maarten Fornerod
Structure (London, England : 1993), 2013, 21 (8), pp.1338-49
Journal articles hal-01322366v1

Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B.

Emilie Montellier , Fayçal Boussouar , Sophie Rousseaux , Kai Zhang , Thierry Buchou
Genes and Development, 2013, 27 (15), pp.1680-92
Journal articles hal-01322388v1
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Identification of a novel BET bromodomain inhibitor-sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers.

Anouk Emadali , Sophie Rousseaux , Juliana Bruder-Costa , Claire Rome , Samuel Duley
EMBO Molecular Medicine, 2013, 5 (8), pp.1180-95. ⟨10.1002/emmm.201202034⟩
Journal articles inserm-00852222v1
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Insights into the function of the CRM1 cofactor RanBP3 from the structure of its Ran-binding domain.

Karla Langer , Cyril Dian , Vladimir Rybin , Christoph W Müller , Carlo Petosa
PLoS ONE, 2011, 6 (2), pp.e17011. ⟨10.1371/journal.pone.0017011⟩
Journal articles cea-00605750v1

Cooperative binding of two acetylation marks on a histone tail by a single bromodomain

Jeanne Morinière , Sophie Rousseaux , Ulrich Steuerwald , Montserrat Soler-López , Sandrine Curtet
Nature Clinical Practice Gastroenterology and Hepatology, 2009, 461 (7264), pp.664-668. ⟨10.1038/nature08397⟩
Journal articles cea-00909643v1