Carlo Petosa

Publications

Article dans une revue (30)

Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors With Antifungal Potential Kaiyao Wei,Marie Arlotto,Justin Overhulse,Tuan‐anh Dinh,Yingsheng Zhouet al. Advanced Science, 2025, 12 (10), pp.e2404260. ⟨10.1002/advs.202404260⟩ Article dans une revue hal-04912139v1
Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet Domenico Iuso,Isabel Garcia-Saez,Yohann Couté,Yoshiki Yamaryo-Botté,Elisabetta Boeri Erbaet al. Science Advances , 2023, 9 (36), pp.eadh0140. ⟨10.1126/sciadv.adh0140⟩ Article dans une revue hal-04216158v1
Enantioselective approach for expanding the three‐dimensional space of tetrahydroquinoline to develop bet bromodomain inhibitors Marie‐ange Lespinasse,Kaiyao Wei,Justine Perrin,Matthias Winkler,Sieme Hamaidiaet al. Chemistry - A European Journal, 2022, 28 (64), pp.e202202293. ⟨10.1002/chem.202202293⟩ Article dans une revue hal-03806738v1
Structural basis of DNA methylation-dependent site selectivity of the Epstein–Barr virus lytic switch protein ZEBRA/Zta/BZLF1 Florent Bernaudat,Montse Gustems,Johannes Günther,Mizar Oliva,Alexander Buschleet al. Nucleic Acids Research, 2022, ⟨10.1093/nar/gkab1183⟩ Article dans une revue hal-03518161v1
Binding stoichiometry and structural model of the HIV-1 Rev/Importin β complex Didier Spittler,Rose-Laure Indorato,Elisabetta Boeri Erba,Elise Delaforge,Luca Signoret al. Life Science Alliance, 2022, ⟨10.26508/lsa.202201431⟩ Article dans une revue hal-03453423v2
Toward more potent imidazopyridine inhibitors of Candida albicans Bdf1: Modeling the role of structural waters in selective ligand binding Yingsheng Zhou,Justin Overhulse,Nathan Dupper,Yanchun Guo,Boris Kashemirovet al. Journal of Computational Chemistry, 2022, 43, pp.2121-2130. ⟨10.1002/jcc.26997⟩ Article dans une revue hal-03806660v1
ATAD2 controls chromatin-bound HIRA turnover Tao Wang,Daniel Perazza,Fayçal Boussouar,Fayçal Boussouar,Alexandre Bougdouret al. Life Science Alliance, 2021, ⟨10.26508/lsa.202101151⟩ Article dans une revue hal-03359419v1
Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends Ramachandran Boopathi,Radostin Danev,Maryam Khoshouei,Seyit Kale,Sunil Nahataet al. Nucleic Acids Research, 2020, 48 (10), pp.5735-5748. ⟨10.1093/nar/gkaa246⟩ Article dans une revue hal-03007422v1
Cryo-electron microscopy of the chromatin fiber Ramachandran Boopathi,Stefan Dimitrov,Ali Hamiche,Carlo Petosa,Jan Bednar Current Opinion in Structural Biology, 2020, 64, pp.97-103. ⟨10.1016/j.sbi.2020.06.016⟩ Article dans une revue hal-02947617v1
Exploring the structure and dynamics of macromolecular complexes by native mass spectrometry Elisabetta Boeri Erba,Luca Signor,Carlo Petosa Journal of Proteomics, 2020, 222, pp.103799. ⟨10.1016/j.jprot.2020.103799⟩ Article dans une revue hal-02864550v1
Phosphomimetic mutations modulate the ability of HIV-1 Rev to bind human Importin β &lt;em&gt;in vitro&lt;/em&gt; Nadia Ben Fadhel,Luca Signor,Carlo Petosa,Marjolaine Noirclerc-Savoye Matters, 2019, ⟨10.19185/matters.201903000032⟩ Article dans une revue hal-02270755v1
A new hope to fight invasive fungal infection Carlo Petosa,Jérôme Govin,Flore Mietton Médecine/Sciences, 2018, 34 (2), pp.123 - 125. ⟨10.1051/medsci/20183402007⟩ Article dans une revue istex hal-01726209v1
Characterizing Intact Macromolecular Complexes Using Native Mass Spectrometry. Elisabetta Boeri Erba,Luca Signor,Mizar Francesca Oliva,Fabienne Hans,Carlo Petosa Methods in Molecular Biology, 2018, 1764, pp.133-151. ⟨10.1007/978-1-4939-7759-8_9⟩ Article dans une revue hal-01807803v1
Structure of an H1-Bound 6-Nucleosome Array Reveals an Untwisted Two-Start Chromatin Fiber Conformation Isabel Garcia-Saez,Hervé Menoni,Ramachandran Boopathi,Manu Shukla,Lama Soueidanet al. Molecular Cell, 2018, 72 (5), pp.902-915.e7. ⟨10.1016/j.molcel.2018.09.027⟩ Article dans une revue hal-02393274v1
Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1. Jan Bednar,Isabel Garcia-Saez,Ramachandran Boopathi,Amber R Cutter,Gabor Papaiet al. Molecular Cell, 2017, 66 (5), pp.729. ⟨10.1016/j.molcel.2017.05.018⟩ Article dans une revue hal-01537811v1
Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Flore Mietton,Elena Ferri,Morgane Champleboux,Ninon Zala,Danièle Maubonet al. Nature Communications, 2017, 8, pp.15482. ⟨10.1038/ncomms15482⟩ Article dans une revue hal-01537809v1
Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein Francesca Coscia,Leandro F Estrozi,Fabienne Hans,Hélène Malet,Marjolaine Noirclerc-Savoyeet al. Scientific Reports, 2016, 6, pp.30909. ⟨10.1038/srep30909⟩ Article dans une revue hal-01396217v1
Data publication with the structural biology data grid supports live analysis Peter A. Meyer,Stephanie Socias,Jason Key,Elizabeth Ransey,Emily C. Tjonet al. Nature Communications, 2016, 7, ⟨10.1038/ncomms10882⟩ Article dans une revue hal-01299025v1
Atad2 is a generalist facilitator of chromatin dynamics in embryonic stem cells Yuichi Morozumi,Fayçal Boussouar,Minjia Tan,Apirat Chaikuad,Mahya Jamshidikiaet al. Journal of molecular cell biology, 2016, 8 (4), pp.349 - 362. ⟨10.1093/jmcb/mjv060⟩ Article dans une revue hal-01415782v1
Bromodomains: Structure, function and pharmacology of inhibition. Elena Ferri,Carlo Petosa,Charles E Mckenna Biochemical Pharmacology, 2016, 106, pp.1-18 Article dans une revue hal-01256715v1
Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters. Afsaneh Goudarzi,Di Zhang,He Huang,Sophie Barral,Oh Kwang Kwonet al. Molecular Cell, 2016, 62 (2), pp.169-80. ⟨10.1016/j.molcel.2016.03.014⟩ Article dans une revue hal-01341099v1
The emerging role of native mass spectrometry in characterizing the structure and dynamics of macromolecular complexes Elisabetta Boeri Erba,Carlo Petosa Protein Science, 2015, 10.1002, pro.2661. ⟨10.1002/pro.2661⟩ Article dans une revue hal-01164101v1
Identification of a novel BET bromodomain inhibitor-sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers. Anouk Emadali,Sophie Rousseaux,Juliana Bruder-Costa,Claire Rome,Samuel Duleyet al. EMBO Molecular Medicine, 2013, 5 (8), pp.1180-95. ⟨10.1002/emmm.201202034⟩ Article dans une revue inserm-00852222v1
Structure of a truncation mutant of the nuclear export factor CRM1 provides insights into the auto-inhibitory role of its C-terminal helix. Cyril Dian,Florent Bernaudat,Karla Langer,Mizar Francesca Oliva,Maarten Fornerodet al. Structure, 2013, 21 (8), pp.1338-49 Article dans une revue hal-01322366v1
Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B Emilie Montellier,Fayçal Boussouar,Sophie Rousseaux,Kai Zhang,Thierry Buchouet al. Genes and Development, 2013, 27 (15), pp.1680-1692. ⟨10.1101/gad.220095.113⟩ Article dans une revue hal-01322388v1
Insights into the function of the CRM1 cofactor RanBP3 from the structure of its Ran-binding domain. Karla Langer,Cyril Dian,Vladimir Rybin,Christoph W Müller,Carlo Petosa PLoS ONE, 2011, 6 (2), pp.e17011. ⟨10.1371/journal.pone.0017011⟩ Article dans une revue cea-00605750v1
Cooperative binding of two acetylation marks on a histone tail by a single bromodomain Jeanne Morinière,Sophie Rousseaux,Ulrich Steuerwald,Montserrat Soler-López,Sandrine Curtetet al. Nature Clinical Practice Gastroenterology and Hepatology, 2009, 461 (7264), pp.664-668. ⟨10.1038/nature08397⟩ Article dans une revue istex cea-00909643v1
Structural Basis of Lytic Cycle Activation by the Epstein-Barr Virus ZEBRA Protein Carlo Petosa,Patrice Morand,Florence Baudin,Martine Moulin,Jean-Baptiste Arteroet al. Molecular Cell, 2006, 21 (4), pp.565-572. ⟨10.1016/j.molcel.2006.01.006⟩ Article dans une revue hal-05285174v1
Architecture of CRM1/Exportin1 Suggests How Cooperativity Is Achieved during Formation of a Nuclear Export Complex Carlo Petosa,Guy Schoehn,Peter Askjaer,Ulrike Bauer,Martine Moulinet al. Molecular Cell, 2004, 16 (5), pp.761-775. ⟨10.1016/j.molcel.2004.11.018⟩ Article dans une revue hal-05285202v1
Crystal structure of the M1 protein-binding domain of the Influenza A virus nuclear export protein (NEP/NS2) Hatice Akarsu,Wilhelm Pascal Burmeister,Carlo Petosa,Isabelle Petit-Hartlein,Christoph W. Mülleret al. EMBO Journal, 2003, 22, pp.4646-4655 Article dans une revue hal-05285814v1

Brevet (1)

Tetrahydroquinoline (THQ) compounds Zuzana Macek Jílková,Jérôme Govin,Anouk Emadali,Carlo Petosa,Yung-Sing Wong France, Patent n° : WO2022248475 A1 20221201. 2021 Brevet hal-04864504v1