Caroline Smet-Nocca

Identifiants chercheurs

IdHAL :

caroline-smet-nocca

ORCID :

0000-0002-9793-0882

ResearcherID :

http://www.researcherid.com/rid/G-2868-2012

Publications

Article dans une revue (36)

Effect of PHF-1 hyperphosphorylation on the seeding activity of C-terminal Tau fragments Léa El Hajjar,Emmanuelle Boll,François-Xavier Cantrelle,Clarisse Bridot,Isabelle Landrieuet al. Scientific Reports, 2025, 15 (9975), ⟨10.1038/s41598-025-91867-3⟩ Article dans une revue hal-05004956v1
Regulation of Glycogen Synthase Kinase-3β by Phosphorylation and O-β-Linked N-Acetylglucosaminylation: Implications on Tau Protein Phosphorylation Léa El Hajjar,Adeline Page,Clarisse Bridot,François-Xavier Cantrelle,Isabelle Landrieuet al. Biochemistry, 2024, 63 (12), pp.1513-1533. ⟨10.1021/acs.biochem.4c00095⟩ Article dans une revue hal-04745026v1
Magnetic resonance investigation of conformational responses of tau protein to specific phosphorylation Alessia Lasorsa,Hamida Merzougui,François-Xavier Cantrelle,Giuseppe Sicoli,Elian Dupréet al. Biophysical Chemistry, 2024, Part of special issue Biophysical, Biochemical, and Cellular Events Underlying Proteinopathies Edited by Carmelo La Rosa, Danilo Milardi, Magdalena Ivanova, Andisheh Abedini, Lucie Khemtemourian, Ayyalusamy Ramamoorthy, 305 (107155), pp.107155. ⟨10.1016/j.bpc.2023.107155⟩ Article dans une revue hal-04440623v1
Deciphering the Structure and Formation of Amyloids in Neurodegenerative Diseases With Chemical Biology Tools Isabelle Landrieu,Elian Dupré,Davy Sinnaeve,Léa El Hajjar,Caroline Smet-Nocca Frontiers in Chemistry, 2022, 10, pp.886382. ⟨10.3389/fchem.2022.886382⟩ Article dans une revue hal-03841022v1
Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregates François-Xavier Cantrelle,Anne Loyens,Xavier Trivelli,Oliver Reimann,Clément Despreset al. Frontiers in Molecular Neuroscience, 2021, 14, pp.661368. ⟨10.3389/fnmol.2021.661368⟩ Article dans une revue hal-03428106v1
Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors Clément Despres,Jing Di,François-Xavier Cantrelle,Zizheng Li,Isabelle Huventet al. ACS Chemical Biology, 2019, 14 (6), pp.1363-1379. ⟨10.1021/acschembio.9b00325⟩ Article dans une revue hal-02317189v1
Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects Pascale Barbier,Orgeta Zejneli,Marlène Martinho,Alessia Lasorsa,Valérie Belleet al. Frontiers in Aging Neuroscience, 2019, 11, ⟨10.3389/fnagi.2019.00204⟩ Article dans une revue hal-02279660v1
Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly Modulator Michael Nshanian,Carter Lantz,Piriya Wongkongkathep,Thomas Schrader,Frank-Gerrit Klärneret al. Journal of The American Society for Mass Spectrometry, 2019, 30 (1), pp.16-23. ⟨10.1007/s13361-018-2027-6⟩ Article dans une revue hal-02543395v1
The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention? Yann Fichou,Youssra K Al-Hilaly,François Devred,Caroline Smet-Nocca,Philipp O Tsvetkovet al. Acta Neuropathologica Communications, 2019, 7 (1), ⟨10.1186/s40478-019-0682-x⟩ Article dans une revue hal-02055894v1
The O-β-linked N-acetylglucosaminylation of the Lamin B receptor and its impact on DNA binding and phosphorylation Caroline Smet-Nocca,Adeline Page,Francois-Xavier Cantrelle,Eleni Nikolakaki,Isabelle Landrieuet al. Biochimica et Biophysica Acta (BBA) - General Subjects, 2018, 1862 (4), pp.825-835. ⟨10.1016/j.bbagen.2018.01.007⟩ Article dans une revue hal-02353573v1
Direct Crosstalk Between O-GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy Gwendoline Bourré,François-Xavier Cantrelle,Amina Kamah,Béatrice Chambraud,Isabelle Landrieuet al. Frontiers in Endocrinology, 2018, 9, ⟨10.3389/fendo.2018.00595⟩ Article dans une revue hal-02337415v1
Identification of the Tau phosphorylation pattern that drives its aggregation Clement Despres,Cillian Byrne,Haoling Qi,François-Xavier Cantrelle,Isabelle Huventet al. Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (34), pp.9080 - 9085. ⟨10.1073/pnas.1708448114⟩ Article dans une revue hal-01620128v1
Semi-synthesis of a tag-free O -GlcNAcylated tau protein by sequential chemoselective ligation Sergej Schwagerus,Oliver Reimann,Clement Despres,Caroline Smet-Nocca,Christian P. R. Hackenberger Journal of Peptide Science, 2016, 22 (5), pp.327 - 333. ⟨10.1002/psc.2870⟩ Article dans une revue istex hal-01389835v1
Proline Conformation in a Functional Tau Fragment Puneet Ahuja,Xavier Cantrelle,Isabelle Huvent,Xavier Hanoulle,Juan Lopezet al. Journal of Molecular Biology, 2016, 428 (1), pp.79 - 91. ⟨10.1016/j.jmb.2015.11.023⟩ Article dans une revue istex hal-01389832v1
NMR Meets Tau: Insights into Its Function and Pathology Guy Lippens,Isabelle Landrieu,Caroline Smet,Isabelle Huvent,Neha Gandhiet al. Ancient biomolecules, 2016, 6 (2), ⟨10.3390/biom6020028⟩ Article dans une revue (article de synthèse) hal-01389829v1
Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins Clément Danis,Clement Despres,Luiza M. Bessa,Idir Malki,Hamida Merzouguiet al. Journal of visualized experiments : JoVE, 2016, 118, ⟨10.3791/55001⟩ Article dans une revue hal-01620152v1
Isomerisation and oligomerization of truncated and mutated tau forms by FKBP52 are independent processes. A Kamah,F X Cantrelle,I Huvent,J Giustiniani,K Guillemeauet al. Journal of Molecular Biology, 2016, 428 (6), pp.1080-1090. ⟨10.1016/j.jmb.2016.02.015⟩ Article dans une revue hal-01278622v1
Traceless Purification and Desulfurization of Tau Protein Ligation Products Oliver Reimann,Caroline Smet-Nocca,Christian P. R. Hackenberger Angewandte Chemie International Edition, 2015, 54 (1), pp.306 - 310. ⟨10.1002/anie.201408674⟩ Article dans une revue istex hal-01389837v1
Interplay between troponin T phosphorylation and O-N-acetylglucosaminylation in ischaemic heart failure Emilie Dubois-Deruy,Aude Belliard,Paul Mulder,Marion Bouvet,Caroline Smet-Noccaet al. Cardiovascular Research, 2015, 107 (1), pp.56-65. ⟨10.1093/cvr/cvv136⟩ Article dans une revue inserm-03833102v1
Nuclear magnetic resonance spectroscopy characterization of interaction of Tau with DNA and its regulation by phosphorylation. Haoling Qi,François-Xavier Cantrelle,Houda Benhelli-Mokrani,Caroline Smet-Nocca,Luc Buéeet al. Biochemistry, 2015, 54 (7), pp.1525-33 Article dans une revue hal-01145987v1
Nuclear magnetic resonance analysis of the acetylation pattern of the neuronal Tau protein. Amina Kamah,Isabelle Huvent,François-Xavier Cantrelle,Haoling Qi,Guy Lippenset al. Biochemistry, 2014, 53 (18), pp.3020-32. ⟨10.1021/bi500006v⟩ Article dans une revue hal-01077868v1
A functional fragment of Tau forms fibers without the need for an intermolecular cysteine bridge. Isabelle Huvent,Amina Kamah,François-Xavier Cantrelle,Nicolas Barois,Christian Slomiannyet al. Biochemical and Biophysical Research Communications, 2014, 445 (2), pp.299-303. ⟨10.1016/j.bbrc.2014.01.161⟩ Article dans une revue istex hal-01077911v1
A TDG/CBP/RARα Ternary Complex Mediates the Retinoic Acid-dependent Expression of DNA Methylation-sensitive Genes Arndt G. Benecke,Sebastian Eilebrecht,Hélène Léger,Caroline Smet-Nocca,Amel Attmane-Elakebet al. Genomics, Proteomics and Bioinformatics, 2014, 12 (1), pp.8-18. ⟨10.1016/j.gpb.2013.11.001⟩ Article dans une revue hal-01544142v1
50nm-Scale Localization of Single Unmodified, Isotopically Enriched, Proteins in Cells Anthony Delaune,Armelle Cabin-Flaman,Guillaume Legent,David Gibouin,Caroline Smet-Noccaet al. PLoS ONE, 2013, 8 (2), pp.e56559. ⟨10.1371/journal.pone.0056559⟩ Article dans une revue hal-01544145v1
Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker. Kunie Ando,Pierre Dourlen,Anne-Véronique Sambo,Alexis Bretteville,Karim Bélarbiet al. Neurobiol Aging, 2013, 34 (3), pp.757-69. ⟨10.1016/j.neurobiolaging.2012.08.004⟩ Article dans une revue istex hal-00765859v1
Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA. Caroline Smet-Nocca,Hélène Launay,Jean-Michel Wieruszeski,Guy Lippens,Isabelle Landrieu Journal of Biomolecular NMR, 2013, 55 (4), pp.323-37. ⟨10.1007/s10858-013-9716-z⟩ Article dans une revue istex hal-00903359v1
50nm scale localization of single unmodified, isotopically enriched, proteins in cells Anthony Delaune,Armelle Cabin-Flaman,Guillaume Legent,David Gibouin,Caroline Smet-Noccaet al. PLoS ONE, 2013, 8, pp.e56559 Article dans une revue hal-04441019v1
Cell signaling, post-translational protein modifications and NMR spectroscopy. Francois-Xavier Theillet,Caroline Smet-Nocca,Stamatios Liokatis,Rossukon Thongwichian,Jonas Kostenet al. Journal of Biomolecular NMR, 2012, 54 (3), pp.217-36. ⟨10.1007/s10858-012-9674-x⟩ Article dans une revue hal-00765863v1
Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice. Peter Borghgraef,Clément Menuet,Clara Theunis,Justin V Louis,Herman Devijveret al. PLoS ONE, 2012, pp.e84442 Article dans une revue hal-01077942v1
Molecular Basis for an Ancient Partnership between Prolyl Isomerase Pin1 and Phosphatase Inhibitor-2. Furqan Sami,Caroline Smet-Nocca,Meera Khan,Isabelle Landrieu,Guy Lippenset al. Biochemistry, 2011, 50 (30), pp.6567-78. ⟨10.1021/bi200553e⟩ Article dans une revue hal-00618273v1
Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation. Caroline Smet-Nocca,Malgorzata Broncel,Jean-Michel Wieruszeski,Caroline Tokarski,Xavier Hanoulleet al. Molecular BioSystems, 2011, 7 (5), pp.1420-9. ⟨10.1039/c0mb00337a⟩ Article dans une revue hal-00586849v1
Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau. Isabelle Landrieu,Caroline Smet-Nocca,Laziza Amniai,Justin Vijay Louis,Jean-Michel Wieruszeskiet al. PLoS ONE, 2011, 6 (6), pp.e21521. ⟨10.1371/journal.pone.0021521⟩ Article dans une revue hal-00618270v1
NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease. Isabelle Landrieu,Arnaud Leroy,Caroline Smet-Nocca,Isabelle Huvent,Laziza Amniaiet al. Biochemical Society Transactions, 2010, 38 (4), pp.1006-11. ⟨10.1042/BST0381006⟩ Article dans une revue hal-00586933v1
The peptidyl-prolyl isomerase and chaperone Par27 of Bordetella pertussis as the prototype for a new group of parvulins. Hélène Hodak,Alexandre Wohlkönig,Caroline Smet-Nocca,Hervé Drobecq,Jean-Michel Wieruszeskiet al. Journal of Molecular Biology, 2008, 376 (2), pp.414-26. ⟨10.1016/j.jmb.2007.10.088⟩ Article dans une revue istex hal-00273348v1
Studying the natively unfolded neuronal Tau protein by solution NMR spectroscopy. Guy Lippens,Alain Sillen,Caroline Smet,Jean-Michel Wieruszeski,Arnaud Leroyet al. Protein and Peptide Letters, 2006, 13, pp.235-246 Article dans une revue hal-00085628v1
Exploring the Molecular Function of PIN1 by Nuclear Magnetic Resonance. Isabelle Landrieu,Caroline Smet,Jean-Michel Wieruszeski,Anne-Véronique Sambo,René Wintjenset al. Current Protein and Peptide Science, 2006, 7, pp.179-194 Article dans une revue hal-00085621v1

Pré-publication, Document de travail (1)

Hydrodynamic Radius Determination of Tau and AT8 Phosphorylated Tau Mutants: A Combined Simulation and Experimental Study Cynthia Lohberger,Jules Marien,Clarisse Bridot,Chantal Prévost,Diane Allegroet al. 2025 Pré-publication, Document de travail hal-05338487v1

Chapitre d'ouvrage (4)

Phosphorylation of Tau Protein by CDK2/cyclin A and GSK3β Recombinant Kinases: Analysis of Phosphorylation Patterns by Nuclear Magnetic Resonance Spectroscopy Léa El Hajjar,Clarisse Bridot,Marine Nguyen,François-Xavier Cantrelle,Isabelle Landrieuet al. Tau Protein, 2754, Springer US, pp.271-306, 2024, Methods in Molecular Biology, ⟨10.1007/978-1-0716-3629-9_15⟩ Chapitre d'ouvrage hal-04745030v1
The O-GlcNAc Modification of Recombinant Tau Protein and Characterization of the O-GlcNAc Pattern for Functional Study Léa El Hajjar,Clarisse Bridot,Marine Nguyen,François-Xavier Cantrelle,Isabelle Landrieuet al. Tau Protein, 2754, Springer US, pp.237-269, 2024, Methods in Molecular Biology, ⟨10.1007/978-1-0716-3629-9_14⟩ Chapitre d'ouvrage hal-04745031v1
Nuclear Magnetic Resonance Spectroscopy Insights into Tau Structure in Solution: Impact of Post-translational Modifications Clément Danis,Elian Dupré,Xavier Hanoulle,Isabelle Landrieu,Alessia Lasorsaet al. Advanced in Experimental Medical Biology, pp.35-45, 2019, ⟨10.1007/978-981-32-9358-8_3⟩ Chapitre d'ouvrage hal-02506938v1
The Study of Posttranslational Modifications of Tau Protein by Nuclear Magnetic Resonance Spectroscopy: Phosphorylation of Tau Protein by ERK2 Recombinant Kinase and Rat Brain Extract, and Acetylation by Recombinant Creb-Binding Protein Haoling Qi,Clément Despres,Sudhakaran Prabakaran,Francois-Xavier Cantrelle,Béatrice Chambraudet al. Nocca Smet, Caroline. Tau protein : methods and protocols, 1523, Springer New York, pp.179-213, 2017, 978-1-4939-6596-0. ⟨10.1007/978-1-4939-6598-4_11⟩ Chapitre d'ouvrage hal-03235823v1

Ouvrages (2)

Tau Protein Caroline Smet-Nocca Caroline Smet-Nocca. Springer US, 2754, 2024, Methods in Molecular Biology, 978-1-0716-3628-2. ⟨10.1007/978-1-0716-3629-9⟩ Ouvrages hal-05165479v1
Tau Protein Caroline Smet-Nocca Caroline Smet-Nocca. Springer New York, 1523, 2017, Methods in Molecular Biology, 978-1-4939-6596-0. ⟨10.1007/978-1-4939-6598-4⟩ Ouvrages hal-05165458v1

Communication dans un congrès (1)

Premier spectromètre RMN 1,2 GHz français : quelles nouvelles possibilités pour l’analyse ? Fabien Ferrage,Pierre Florian,Guy Lippens,Emmanuel Maes,Guido Pintacudaet al. Réunion des utilisateurs RMN de Bruker France, Nov 2023, Lille, France Communication dans un congrès hal-04470791v1

Thèse (1)

Etude des interactions entre la peptidyl-prolyl cis/trans isomérase Pin1 et la protéine microtubulaire Tau. Recherche d'inhibiteurs ciblant la liaison de Pin1 à ses substrats phosphorylés Caroline Smet-Nocca Biochimie [q-bio.BM]. Université du Droit et de la Santé - Lille II, 2004. Français. ⟨NNT : ⟩ Thèse tel-00354986v1