Cecile Legallais

159
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Présentation

Cécile LEGALLAIS

Date of birth : 07/03/1968

cecile.legallais@utc.fr

PRESENT POSITION

2018 - : Head of Laboratory of Biomechanics and Bioengineering (joint lab Université de Technologie de Compiè(UTC)/CNRS)

APPOINTMENTS

2006 - : Directeur de recherche CNRS (CNRS Senior researcher). Laboratory of Biomechanics and Bioengineering, Université de Technologie de Compiègne (FR)

2015 - 2018 :Associate Researcher (part time) Assistance Publique Hôpitaux de Paris (APHP)

1996 - 1997 : Post-doctoral Fellow, University of Calabria (Italy) & Membrana GmbH (Germany)

1993 - 2006 : Chargé de recherche CNRS (CNRS Researcher). UTC Compiègne

ACADEMIC QUALIFICATIONS

H.D.R. 1998 “Habilitation” to supervise Ph.D. Thesis. Université de Technologie de Compiègne (FR). Blood toxins removal by membrane processes.

Ph. D. 1993Université de Technologie de Compiègne (FR). Specialty : Biomedical Eng. LDL-cholesterol removal from human plasma based on cascade filtration.

MS/Eng. D 1990 Ecole Nationale Supérieure de Mécanique et Aérotechnique (Poitiers) – Engineer in Fluid Mechanics

AWARDS

Bronze Medal from the CNRS, 2003.

RESEARCH ACTIVITIES : Biomechanics of Organ Supply systems

Since 1995 : Bioartificial liver at different scales. Encapsulation of hepatoctes in alginate beads. Design and characterization of fluidized bed bioreactor. Full extracorporeal circulation. PI of ANR TecSan SUPPLIVER (2011 -2015). WP Leader RHU Ilite (Innovations in Liver tissue Engineering) (2016-2022). PI of ANR MimLiveronChip (Organ on Chip) (2019-2023)

Since 2006: Bone and musculo-skeletal tissue engineering based on stretching bioreactors – Mechanical and biological characterization.

Since 1994: Flow and Mass transfer in hemodialysis and hemodiafiltration : Collaboration with Membrana GmbH, Fresenius Medical Care, Amiens Hospital

Since 2000 : Blood flow simulations in 3D vessels reconstructed from medical images.

PUBLICATIONS and COMMUNICATIONS

- 105 papers in international journals with peer review

- 6 book chapters, 4 patents

SYNERGISTIC ACTIVITIES

- Past President (2019-2021) of European Society for Artificial Organs (ESAO). Formerly Governor (2005-2011), General Secretary (2011-2015), President Elect (2015-2017)& President (2017-2019).

- Member of the Board of the International Federation for Artificial Organs (IFAO)

- President of the XXXVIth ESAO Congress (2009) in Compiègne, France (400 participants)

- Reviewer for Artificial Organs, Journal of Membrane Science, Biotechnology Bioengineering, Separation Science and Technology, Journal of Polymer Science, Journal of Biomechanics, Medical Engineering and Physics, Plos One, Tissue Engineering, Biomaterials.

SUPERVISION

- 25 PhD students at UTC (22 achieved, 3 ongoing)

- 3 HDR Habilitation at UTC

TEACHING ACTIVITIES

- Lecture on Artificial Organs (UTC) – 20h/y

- Hands on activities for engineering students (tissue engineering, hemodialysis)

Publications

Publications

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Organoids-on-chip models to mimic liver physiology

A. Brassens , A. Martins , T. Messelmani , Ulysse Pereira , J.M. Prot et al.
Multidisciplinary Biomechanics Journal, 2025, 49th congress of the Société de Biomécanique, ⟨10.46298/mbj.14576⟩
Article dans une revue hal-04738069 v2
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Transcriptomic profiling analysis of the effect of palmitic acid on 3D spheroids of β-like cells derived from induced pluripotent stem cells

Lisa Morisseau , Fumiya Tokito , Mathilde Lucas , Stéphane Poulain , Soo Hyeon Kim et al.
Gene, 2024, 917, pp.148441. ⟨10.1016/j.gene.2024.148441⟩
Article dans une revue hal-04608624 v1
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Comparison of hydroxyapatite and honeycomb micro-structure in bone tissue engineering using electrospun beads-on-string fibers

Nicolas Rivoallan , Marc Mueller , Timothée Baudequin , Pascale Vigneron , Anne Hébraud et al.
The International Journal of Artificial Organs, 2024, The International Journal of Artificial Organs, Volume 47, Issue 8 Pages: 642 - 649, 47 (8), pp.642-649. ⟨10.1177/03913988241268033⟩
Article dans une revue hal-04742155 v1

Investigation of the motif activity of transcription regulators in pancreatic β-like cell subpopulations differentiated from human induced pluripotent stem cells

Eric Leclerc , Mikhail Pachkov , Lisa Morisseau , Fumiya Tokito , Cecile Legallais et al.
Molecular Omics, 2024, ⟨10.1039/D4MO00082J⟩
Article dans une revue hal-04787625 v1
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Flow rate variations in microfluidic circuits with free surfaces

Taha Messelmani , Isabela Zarpellon Nascimento , Eric Leclerc , Cécile Legallais , Adam Meziane et al.
Microfluidics and Nanofluidics, 2023, 27 (12), pp.79. ⟨10.1007/s10404-023-02691-y⟩
Article dans une revue hal-04257314 v1
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Investigation of the metabolomic crosstalk between liver sinusoidal endothelial cells and hepatocytes exposed to paracetamol using organ-on-chip technology

Taha Messelmani , Anne Le Goff , Fabrice Soncin , Françoise Gilard , Zied Souguir et al.
Toxicology, 2023, 492, pp.153550. ⟨10.1016/j.tox.2023.153550⟩
Article dans une revue hal-04212804 v1
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Microencapsulated Hepatocytes Differentiated from Human Induced Pluripotent Stem Cells: Optimizing 3D Culture for Tissue Engineering Applications

Marwa Hussein , Mattia Pasqua , Ulysse Pereira , Nassima Benzoubir , Jean-Charles Duclos-Vallée et al.
Cells, 2023, 12 (6), pp.865. ⟨10.3390/cells12060865⟩
Article dans une revue hal-04193769 v1
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Generation of β-like cell subtypes from differentiated human induced pluripotent stem cells in 3D spheroids

Lisa Morisseau , Fumiya Tokito , Stéphane Poulain , Valérie Plaisance , Valerie Pawlowski et al.
Molecular Omics, 2023, 19 (10), pp.810-822. ⟨10.1039/D3MO00050H⟩
Article dans une revue hal-04209565 v1
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Groupe Néphrologie verte de la SFNDT : premières réflexions

Charles Chazot , Hafsah Hachad , Pierre Filipozzi , Cécile Legallais , Perrine Jullien et al.
Néphrologie & Thérapeutique, 2023, 19 (1), pp.23-33. ⟨10.1684/ndt.2023.1⟩
Article dans une revue (article de synthèse) hal-04294264 v1
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Coculture model of a liver sinusoidal endothelial cell barrier and HepG2/C3a spheroids-on-chip in an advanced fluidic platform

Taha Messelmani , Anne Le Goff , Fabrice Soncin , Zied Souguir , Franck Merlier et al.
Journal of Bioscience and Bioengineering, 2023, ⟨10.1016/j.jbiosc.2023.10.006⟩
Article dans une revue hal-04288584 v1
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Analysis of the transcriptome and metabolome of pancreatic spheroids derived from human induced pluripotent stem cells and matured in an organ-on-a-chip

Amal Essaouiba , Rachid Jellali , Stéphane Poulain , Fumiya Tokito , Françoise Gilard et al.
Molecular Omics, 2022, 18 (8), pp.791-804. ⟨10.1039/d2mo00132b⟩
Article dans une revue hal-03861419 v1
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Evidence of Adult Features and Functions of Hepatocytes Differentiated from Human Induced Pluripotent Stem Cells and Self-Organized as Organoids

Antonietta Messina , Eléanor Luce , Nassima Benzoubir , Mattia Pasqua , Ulysse Pereira et al.
Cells, 2022, 11 (3), ⟨10.3390/cells11030537⟩
Article dans une revue hal-03561619 v1
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Liver organ-on-chip models for toxicity studies and risk assessment

Taha Messelmani , Lisa Morisseau , Yasuyuki Sakai , Cécile Legallais , Anne Le Goff et al.
Lab on a Chip, 2022, 22 (13), pp.2423-2450. ⟨10.1039/d2lc00307d⟩
Article dans une revue hal-03861401 v1
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Electrodialysis Can Lower the Environmental Impact of Hemodialysis

Ahmed Abarkan , Nabil Grimi , Hubert Métayer , Tarik Sqalli Houssaïni , C. Legallais
Membranes, 2022, 12 (1), pp.45. ⟨10.3390/membranes12010045⟩
Article dans une revue hal-03590375 v1
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Investigation of the Exometabolomic Profiles of Rat Islets of Langerhans Cultured in Microfluidic Biochip

Amal Essaouiba , Rachid Jellali , Françoise Gilard , Bertrand Gakière , Teru Okitsu et al.
Metabolites, 2022, 12 (12), pp.1270. ⟨10.3390/metabo12121270⟩
Article dans une revue hal-04213642 v1
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Development of Liver-on-Chip Integrating a Hydroscaffold Mimicking the Liver’s Extracellular Matrix

Taha Messelmani , Anne Le Goff , Zied Souguir , Victoria Maes , Méryl Roudaut et al.
Bioengineering, 2022, 9, ⟨10.3390/bioengineering9090443⟩
Article dans une revue hal-03861410 v1
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Multiscale-Engineered Muscle Constructs: PEG Hydrogel Micro-Patterning on an Electrospun PCL Mat Functionalized with Gold Nanoparticles

Megane Beldjilali-Labro , Rachid Jellali , Alexander David Brown , Alejandro Garcia Garcia , Augustin Lerebours et al.
International Journal of Molecular Sciences, 2022, 23 (1), pp.260. ⟨10.3390/ijms23010260⟩
Article dans une revue hal-03590377 v1
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Validation of HepG2/C3A Cell Cultures in Cyclic Olefin Copolymer Based Microfluidic Bioreactors

Leire Etxeberria , Taha Messelmani , Jon Haitz Badiola , Andreu Llobera , Luis Fernandez et al.
Polymers, 2022, 14 (21), pp.4478. ⟨10.3390/polym14214478⟩
Article dans une revue hal-03861408 v1
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Preclinical characterization of alginate‐Poly‐L‐Lysine encapsulated HepaRG for extracorporeal liver supply

Mattia Pasqua , Ulysse Pereira , Claire de Lartigue , Jonathan Nicolas , Pascale Vigneron et al.
Biotechnology and Bioengineering, 2021, 118 (1), ⟨10.1002/bit.27583⟩
Article dans une revue hal-02961888 v1
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Analysis of the behavior of 2D monolayers and 3D spheroid human pancreatic beta cells derived from induced pluripotent stem cells in a microfluidic environment

Amal Essaouiba , Rachid Jellali , Marie Shinohara , Benedikt Scheidecker , Cécile Legallais et al.
Journal of Biotechnology, 2021, 330, pp.45-56. ⟨10.1016/j.jbiotec.2021.02.009⟩
Article dans une revue hal-03285819 v1
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Cryogel-Integrated Biochip for Liver Tissue Engineering

Lilandra Boulais , Rachid Jellali , Ulysse Pereira , Eric Leclerc , Sidi A Bencherif et al.
ACS Applied Bio Materials, 2021, 4 (7), pp.5617-5626. ⟨10.1021/acsabm.1c00425⟩
Article dans une revue hal-03322953 v1
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Donor variability alters differentiation and mechanical cohesion of tissue-engineered constructs with human endothelial/MSC co-culture

Timothée Baudequin , Marie Naudot , Sébastien Dupont , Sylvie Testelin , Bernard Devauchelle et al.
The International Journal of Artificial Organs, 2021, 44 (11), pp.868-879. ⟨10.1177/03913988211051758⟩
Article dans une revue hal-03433092 v2
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Investigation of steatosis profiles induced by pesticides using liver organ-on-chip model and omics analysis

Rachid Jellali , Sebastien Jacques , Amal Essaouiba , Françoise Gilard , Franck Letourneur et al.
Food and Chemical Toxicology, 2021, 152, ⟨10.1016/j.fct.2021.112155⟩
Article dans une revue hal-03285733 v1
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Monitoring mechanical stimulation for optimal tendon tissue engineering: a mechanical and biological multiscale study

Alejandro Garcia Garcia , Jean-Baptiste Perot , Megane Beldjilali-Labro , Quentin Dermigny , Marie Naudot et al.
Journal of Biomedical Materials Research Part A, 2021, ⟨10.1002/jbm.a.37180⟩
Article dans une revue hal-03029652 v1
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Development of a pancreas-liver organ-on-chip coculture model for organ-to-organ interaction studies

Amal Essaouiba , Teru Okitsu , R. Kinoshita , Rachid Jellali , Yasuyuki Sakai et al.
Biochemical Engineering Journal, 2020, 164, pp.107783. ⟨10.1016/j.bej.2020.107783⟩
Article dans une revue hal-03095499 v1
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Electrospinning of biomedically relevant gradient scaffolds: From honeycomb to randomly-oriented microstructure

Christopher Leon-Valdivieso , Alejandro Garcia-Garcia , Cécile Legallais , Fahmi Bedoui
Polymer, 2020, 202, pp.122606. ⟨10.1016/j.polymer.2020.122606⟩
Article dans une revue hal-02884169 v1
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Microwell-based pancreas-on-chip model enhances genes expression and functionality of rat islets of Langerhans

Amal Essaouiba , Teru Okitsu , Rachid Jellali , Marie Shinohara , Mathieu Danoy et al.
Molecular and Cellular Endocrinology, 2020, 112, pp.110892. ⟨10.1016/j.mce.2020.110892⟩
Article dans une revue hal-02884096 v1
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The combination of a poly‐caprolactone/nano‐hydroxyapatite honeycomb scaffold and mesenchymal stem cells promotes bone regeneration in rat calvarial defects

Marie Naudot , Alejandro Garcia Garcia , Nicolas Jankovsky , Anaïs Barre , Luciane Zabijak et al.
Journal of Tissue Engineering and Regenerative Medicine, 2020, 65, pp.20-31. ⟨10.1002/term.3114⟩
Article dans une revue hal-02961861 v1
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HepaRG Self-Assembled Spheroids in Alginate Beads Meet the Clinical Needs for Bioartificial Liver

Mattia Pasqua , Ulysse Pereira , Antonietta Messina , Claire de Lartigue , Pascale Vigneron et al.
Tissue Engineering: Parts A, B, and C, 2020, 26 (11-12), pp.613-622. ⟨10.1089/ten.tea.2019.0262⟩
Article dans une revue hal-02884175 v1
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Cold-to-warm machine perfusion of the liver: a novel circuit for an uninterrupted combined perfusion protocol

Claire Goumard , Eric Savier , Jerome Danion , Jérôme Pelissie , Cécile Legallais et al.
HPB, 2020, 22 (6), pp.927-933. ⟨10.1016/j.hpb.2020.04.001⟩
Article dans une revue hal-02884180 v1
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In Vitro Bone Cell Response to Tensile Mechanical Solicitations: Is There an Optimal Protocol?

Timothée Baudequin , Cécile Legallais , Fahmi Bedoui
Biotechnology Journal, 2019, 14 (1), pp.1800358. ⟨10.1002/biot.201800358⟩
Article dans une revue hal-02061207 v1
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Nanotechnology and Bioartificial Liver Engineering. Two Rival Paths for “Converging Technology”

Xavier Guchet , Cécile Legallais
Philosophia Scientiae, 2019, 23-1, pp.121-135. ⟨10.4000/philosophiascientiae.1839⟩
Article dans une revue hal-02140040 v1
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Bioartificial liver: biomechanical considerations

L. Boulais , M. Pasqua , C. de Lartigue , R. Jellali , U. Pereira et al.
Computer Methods in Biomechanics and Biomedical Engineering, 2019, 44th Congress of the Société de Biomécanique, 22 (sup1), pp.S370-S372. ⟨10.1080/10255842.2020.1714948⟩
Article dans une revue hal-03322978 v1
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Poly(ε-caprolactone)/Hydroxyapatite 3D Honeycomb Scaffolds for a Cellular Microenvironment Adapted to Maxillofacial Bone Reconstruction

Alejandro Garcia Garcia , Anne Hebraud , Jean-Luc Duval , Corinne Wittmer , Ludovic Gaut et al.
ACS Biomaterials Science and Engineering, 2018, 4 (9), pp.3317-3326. ⟨10.1021/acsbiomaterials.8b00521⟩
Article dans une revue hal-02393845 v1
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Biomaterials in Tendon and Skeletal Muscle Tissue Engineering: Current Trends and Challenges

Megane Beldjilali-Labro , Alejandro Garcia Garcia , Firas Farhat , Fahmi Bedoui , Jean-François Grosset et al.
Materials, 2018, 11 (7), pp.1116. ⟨10.3390/ma11071116⟩
Article dans une revue hal-01956820 v1

Metabolomics-on-a-chip approach to study hepatotoxicity of DDT, permethrin and their mixtures

Rachid Jellali , Françoise Gilard , Vittoria Pandolfi , Audrey Legendre , Marie-José Fleury et al.
Journal of Applied Toxicology, 2018, 38 (8), pp.1121-1134. ⟨10.1002/jat.3624⟩
Article dans une revue hal-02357461 v1
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Bioengineering Organs for Blood Detoxification

Cécile Legallais , Dooli Kim , Sylvia Mihaila , Milos Mihajlovic , Marina Figliuzzi et al.
Advanced Healthcare Materials, 2018, 7 (21), pp.1800430. ⟨10.1002/adhm.201800430⟩
Article dans une revue hal-01956818 v1

Mass Transfers in a Fluidized Bed Bioreactor using Alginate Beads for a Future Bioartificial Liver

B. David , E. Dore , M.Y. Jaffrin , C. Legallais
The International Journal of Artificial Organs, 2018, 27 (4), pp.284-293. ⟨10.1177/039139880402700404⟩
Article dans une revue hal-02149863 v1
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The Osteogenic and Tenogenic Differentiation Potential of C3H10T1/2 (Mesenchymal Stem Cell Model) Cultured on PCL/PLA Electrospun Scaffolds in the Absence of Specific Differentiation Medium

Timothée Baudequin , Ludovic Gaut , Marc Mueller , Angela Huepkes , Birgit Glasmacher et al.
Materials, 2017, 10 (12), pp.1387. ⟨10.3390/ma10121387⟩
Article dans une revue hal-02938374 v1
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Alginate-Based Cell Microencapsulation for Tissue Engineering and Regenerative Medicine

Vittoria Pandolfi , Ulysse Pereira , Murielle Dufresne , Cécile Legallais
Current Pharmaceutical Design, 2017, 23 (26), ⟨10.2174/1381612823666170609084016⟩
Article dans une revue hal-02938367 v1
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A new prescription model for regional citrate anticoagulation in therapeutic plasma exchanges

Sébastien Kissling , Cécile Legallais , Menno Pruijm , Daniel Teta , Bruno Vogt et al.
BMC Nephrology, 2017, 18 (1), pp.81. ⟨10.1186/s12882-017-0494-9⟩
Article dans une revue hal-02938371 v1

Optimizing the fluidized bed bioreactor as an external bioartificial liver

Sarah Figaro , Ulysse Pereira , Hiram Rada , Nicolas Semenzato , Dominique Pouchoulin et al.
The International Journal of Artificial Organs, 2017, 40 (4), pp.196-203. ⟨10.5301/ijao.5000567⟩
Article dans une revue hal-02938255 v1

Expansion properties of alginate beads as cell carrier in the fluidized bed bioartificial liver

Seyed Danial Naghib , Vittoria Pandolfi , Ulysse Pereira , Rossella Girimonte , Efrem Curcio et al.
Powder Technology, 2017, 316, pp.711-717. ⟨10.1016/j.powtec.2016.12.047⟩
Article dans une revue hal-02938369 v1
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Towards the Development and Characterization of an Easy Handling Sheet-Like Biohybrid Bone Substitute

Timothée Baudequin , Fahmi Bedoui , Murielle Dufresne , Patrick Paullier , Cécile Legallais
Tissue Engineering: Parts A, B, and C, 2015, 21 (11-12), pp.1895-1905. ⟨10.1089/ten.tea.2014.0580⟩
Article dans une revue hal-03433119 v1

SUPPLIVER: Bioartificial supply for liver failure

S. Figaro , Ulysse Pereira , A-S. Dumé , H. Rada , S. Capone et al.
Innovation and Research in BioMedical engineering, 2015, 36 (2), pp.101-109. ⟨10.1016/j.irbm.2015.01.010⟩
Article dans une revue hal-03411627 v1

Numerical simulation of the fluid structure interactions in a compliant patient-specific arteriovenous fistula

Iolanda Decorato , Zaher Kharboutly , Tommaso Vassallo , Justin Penrose , Cécile Legallais et al.
International Journal for Numerical Methods in Biomedical Engineering, 2014, 30 (2), pp.143-159. ⟨10.1002/cnm.2595⟩
Article dans une revue istex hal-02019727 v1

Comparison of two Endovascular Treatments of a Stenosed Arteriovenous Fistula: Balloon-Angioplasty with and without Stenting

Iolanda Decorato , Zaher Kharboutly , Cécile Legallais , Anne-Virginie Salsac
The International Journal of Artificial Organs, 2014, 37 (10), pp.763-772. ⟨10.5301/ijao.5000324⟩
Article dans une revue hal-02019770 v1

Influence of an Arterial Stenosis on the Hemodynamics Within an Arteriovenous Fistula (AVF): Comparison Before and After Balloon-Angioplasty

Iolanda Decorato , Anne-Virginie Salsac , Cécile Legallais , Mona Alimohammadi , Vanessa Diaz-Zuccarini et al.
Cardiovascular Engineering and Technology, 2014, 5 (3), pp.233-243. ⟨10.1007/s13239-014-0185-7⟩
Article dans une revue hal-02019623 v1

Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips

Régis Baudoin , Jean-Matthieu Prot , Grégory Nicolas , Jessy Brocheton , Céline Brochot et al.
Xenobiotica, 2013, 43 (2), pp.140-152. ⟨10.3109/00498254.2012.706725⟩
Article dans une revue ineris-00963431 v1
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Human hepatic cell behavior on polysulfone membrane with double porosity level

Murielle Dufresne , Patrice Bacchin , Giulia Cerino , Jean-Christophe Remigy , Gerard Nathanael Adrianus et al.
Journal of Membrane Science, 2013, vol. 428, pp. 454-461. ⟨10.1016/j.memsci.2012.10.041⟩
Article dans une revue hal-00788387 v1

An appropriate selection of 3D alginate culture model for hepatic Huh-7 cell line encapsulation intended for viral studies

N.M. Tran , M. Dufresne , Gilles Duverlie , Sandrine Castelain , Christian Défarge et al.
Tissue Engineering: Parts A, B, and C, 2013, 19 (1-2), pp.103-113. ⟨10.1089/ten.tea.2012.0139⟩
Article dans une revue insu-00723045 v1

Investigation of ifosfamide nephrotoxicity induced in a liver-kidney co-culture biochip.

Leila Choucha-Snouber , Caroline Aninat , Laurent Grsicom , Geoffrey Madalinski , Céline Brochot et al.
Biotechnology and Bioengineering, 2013, 110 (2), pp.597-608. ⟨10.1002/bit.24707⟩
Article dans une revue istex inserm-00864839 v1
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Impact of Alginate Composition: From Bead Mechanical Properties to Encapsulated HepG2/C3A Cell Activities for In Vivo Implantation

Stephanie Capone , Murielle Dufresne , Mathias Rechel , Marie-José Fleury , Anne-Virginie Salsac et al.
PLoS ONE, 2013, 8 (4), pp.e62032. ⟨10.1371/journal.pone.0062032⟩
Article dans une revue hal-02019744 v1

Metabolomics-on-a-chip of hepatotoxicity induced by anticancer drug flutamide and its active metabolite hydroxyflutamide using HepG2/C3a microfluidic biochips

Leila Choucha-Snouber , Andrei Bunescu , Cécile Legallais , Céline Brochot , Marc-Emmanuel Dumas et al.
Toxicological Sciences, 2013, 132 (1), pp.8-20. ⟨10.1093/toxsci/kfs230⟩
Article dans une revue ineris-00963445 v1

Metabolomics-on-a-Chip and Predictive Systems Toxicology in Microfluidic Bioartificial Organs

Laetitia Shintu , Régis Baudoin , Vincent Navratil , Jean-Matthieu Prot , Clément Pontoizeau et al.
Analytical Chemistry, 2012, 84 (4), pp.1840-1848. ⟨10.1021/ac2011075⟩
Article dans une revue hal-00699575 v1
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Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: Application to acetaminophen injury

Jean-Matthieu Prot , Andrei Bunescu , Bénédicte Elena-Herrmann , Caroline Aninat , Leila Choucha Snouber et al.
Toxicology and Applied Pharmacology, 2012, 259 (3), pp.270-280. ⟨10.1016/j.taap.2011.12.017⟩
Article dans une revue hal-00699551 v1

ENDOCOM: Implantable wireless pressure sensor for the follow-up of abdominal aortic aneurysm stented

Olivier Romain , Johan Mazeyrat , Patrick Garda , Hakeim Talleb , David Lautru et al.
Innovation and Research in BioMedical engineering, 2011, 32 (3), pp.163 - 168. ⟨10.1016/j.irbm.2011.01.017⟩
Article dans une revue istex hal-00665334 v1

Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip

J.M. Prot , A.S. Briffaut , F. Letourneur , P. Chafey , F. Merlier et al.
PLoS ONE, 2011, 6 (8), pp.e21268. ⟨10.1371/journal.pone.0021268⟩
Article dans une revue hal-00637409 v1

Improvement of HepG2/C3a cell functions in a microfluidic biochip.

Jean Matthieu Prot , Caroline Aninat , Laurent Griscom , Florence Razan , Céline Brochot et al.
Biotechnology and Bioengineering, 2011, 108 (7), pp.1704-15. ⟨10.1002/bit.23104⟩
Article dans une revue istex hal-00740224 v1

A cocktail of metabolic probes demonstrates the relevance of primary human hepatocyte cultures in a microfluidic biochip for pharmaceutical drug screening

Jean-Matthieu Prot , Orianne Videau , Céline Brochot , Cécile Legallais , Henri Benech et al.
International Journal of Pharmaceutics, 2011, 108 (1-2), pp.67-75. ⟨10.1016/j.ijpharm.2011.01.054⟩
Article dans une revue istex ineris-00963290 v1

Numerical and experimental study of blood flow through a patient-specific arteriovenous fistula used for hemodialysis

Zaher Kharboutly , Valérie Deplano , Eric Bertrand , Cécile Legallais
Medical Engineering & Physics, 2010, 32, pp.111-118. ⟨10.1016/j.medengphy.2009.10.013⟩
Article dans une revue istex hal-00429960 v1

Analysis of the mass transfers in an artificial kidney microchip

A. Ould-Dris , P. Paullier , Laurent Griscom , Cécile Legallais , E. Leclerc
Journal of Membrane Science, 2010, 352, pp.116-125. ⟨10.1016/j.memsci.2010.02.007⟩
Article dans une revue istex hal-00592403 v1

Prédiction de la toxicocinétique in vivo de substances chimiques à partir de données in vitro et de modèles QSAR

Dany Habka , Alexandre R.R. Pery , Cécile Legallais , Céline Brochot
Environnement, Risques & Santé, 2010, 9 (6), pp.489-501. ⟨10.1684/ers.2010.0396⟩
Article dans une revue ineris-00963259 v1

Alginate-encapsulated HepG2 Cells in a Fluidized Bed Bioreactor Maintain Function in Human Liver Failure Plasma

Sam Coward , Cécile Legallais , Bertrand David , Michael Thomas , Ying Foo et al.
Artificial Organs, 2009, 33 (12), pp.1117-1126. ⟨10.1111/j.1525-1594.2009.00821.x⟩
Article dans une revue istex hal-02149842 v1

Les dispositifs de suppléance hépatique

A. Gautier , C. Legallais
Réanimation, 2009, 18 (5), pp.413-419. ⟨10.1016/j.reaurg.2009.05.010⟩
Article dans une revue hal-00437800 v1

In vitro tests and modelization of bicarbonate kinetics and mass transfers during online hemodiafiltration

H. Morel , M.Y. Jaffrin , P. Paullier , C. Legallais
The International Journal of Artificial Organs, 2009, 32, pp.482-491. ⟨10.1177/039139880903200802⟩
Article dans une revue hal-00437233 v1

Artificial and bioartificial liver devices: present and future

B. Carpentier , A. Gautier , C. Legallais
Gut, 2009, 58 (12), pp.1690-1702. ⟨10.1136/gut.2008.175380⟩
Article dans une revue istex hal-00437697 v1

Hollow fiber bioartificial liver: Physical and biological characterization with C3A cells

A. Gautier , A. Ould-Dris , M. Dufresne , P. Paullier , B. von Harten et al.
Journal of Membrane Science, 2009, 341 ((1-2)), pp.203-213. ⟨10.1016/j.memsci.2009.06.007⟩
Article dans une revue istex hal-00437709 v1

The place of adsorption and biochromatography in extracorporeal liver support systems

C. Legallais , A. Gautier , M. Dufresne , B. Carpentier , R. Baudoin
Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2008, 961 (2), pp.171-176. ⟨10.1016/j.jchromb.2007.07.048⟩
Article dans une revue istex hal-00339871 v1

Three-dimensional growth of human hepatoma C3A cells within alginate beads for fluidized bioartificial liver

A. Kinasiewicz , A. Gautier , D. Lewińska , A. Śmietanka , C. Legallais et al.
The International Journal of Artificial Organs, 2008, 31 (4), pp.340- 347. ⟨10.1177/039139880803100411⟩
Article dans une revue hal-00339867 v1

Solid–liquid mass transfers in an airlift reactor incorporating alginate beads for the application as a bioartificial liver

S. Demming , A. Gautier , C. Legallais , A. Ould-Dris
Chemical Engineering and Processing: Process Intensification, 2008, 47 (12), pp.2370-2378. ⟨10.1016/j.cep.2008.01.013⟩
Article dans une revue istex hal-00336365 v1

Générateurs d'hémodialyse : état du marché français

S. Merlo , A. Donadey , B. Coevoet , C. Legallais
ITBM RBM, 2007, 28, pp.150-168. ⟨10.1016/j.rbmret.2007.07.004⟩
Article dans une revue hal-00282676 v1

Investigations into the relationship between hemodynamics and vascular alterations in an established arteriovenous fistula

Z. Kharboutly , M. Fenech , J.M. Treutenaere , I. Claude , C. Legallais
Medical Engineering & Physics, 2007, 29 (9), pp.999-1007. ⟨10.1016/j.medengphy.2006.10.018⟩
Article dans une revue istex hal-03842143 v1

Development of a renal microchip for in vitro distal tubule models

R. Baudoin , L. Griscom , M. Monge , C. Legallais , E. Leclerc
Biotechnology Progress, 2007, 23, pp.1245-1253. ⟨10.1021/bp0603513⟩
Article dans une revue istex hal-00196149 v1

Trends in the development of microfluidic cell biochips for in vitro hepatotoxicity

R. Baudoin , Anne Corlu , L. Griscom , C. Legallais , E. Leclerc
Toxicology in Vitro, 2007, 21, pp.535-544. ⟨10.1016/j.tiv.2006.11.004⟩
Article dans une revue istex hal-00172268 v1

Selective control of liver and kidney cells migration during organotypic cocultures inside fibronectin-coated rectangular silicone microchannels

Eric Leclerc , Régis Baudoin , Anne Corlu , Laurent Griscom , Jean Luc Duval et al.
Biomaterials, 2007, 28 (10), pp.1820-1829. ⟨10.1016/j.biomaterials.2006.11.044⟩
Article dans une revue istex hal-00172298 v1

Culture of C3A Cells in Alginate Beads for Fluidized Bed Bioartificial Liver.

A. Kinasiewicz , A. Gautier , D. Lewinska , J. Bukowski , C. Legallais et al.
Transplantation Proceedings, 2007, 39 (9), pp.2911-2913. ⟨10.1016/j.transproceed.2007.08.062⟩
Article dans une revue istex hal-00282673 v1

A theoretical study of oxygen transfer including cell necrosis for the design of a bioartificial pancreas

J.L. Dulong , C. Legallais
Biotechnology and Bioengineering, 2007, 96, pp.990-998. ⟨10.1002/bit.21140⟩
Article dans une revue istex hal-00282668 v1

Mechanical properties of alginate beads hosting hepatocytes in a fluidized bed bioreactor.

C David , L. Barbe , D. Barthès-Biesel , C. Legallais
The International Journal of Artificial Organs, 2006, 29 (8), pp.756-63. ⟨10.1177/039139880602900805⟩
Article dans une revue hal-02149847 v1

Study of Osteoblastic Cells in a Microfluidic Environment

E. Leclerc , B. David , L Griscom , Bruno Le Pioufle , T. Fujii et al.
Biomaterials, 2006, 27 (4), pp.558-595. ⟨10.1016/j.biomaterials.2005.06.002⟩
Article dans une revue istex hal-00778216 v1

Perfusion culture of mammalian cells in microfluidic environments for tissue engineering applications

Eric Leclerc , Bertrand David , Laurent Griscom , Bruno Lepioufle , Yasuyuki Sakai et al.
La Houille Blanche - Revue internationale de l'eau, 2006, 3 (3), pp.56-59. ⟨10.1051/lhb:200603008⟩
Article dans une revue istex hal-02149903 v1

Guidance of liver and kidney organotypic cultures inside rectangular silicone microchannels.

E. Leclerc , A. Corlu , L. Griscom , R. Baudoin , C. Legallais
Biomaterials, 2006, 27, pp.4109-4119. ⟨10.1016/j.biomaterials.2006.03.031⟩
Article dans une revue istex hal-00090178 v1

What are the relevant parameters for the geometrical optimization of an implantable bioartificial pancreas ?

J.L. Dulong , C. Legallais
Journal of Biomechanical Engineering, 2005, 127 (7), pp.1054-1061. ⟨10.1115/1.2073407⟩
Article dans une revue hal-00017278 v1

In vitro assessment of encapsulated C3A hepatocytes functions in a fluidized bed bioreactor

B. David , M. M. Dufresne , M. Nagel , C. Legallais
Biotechnology Progress, 2004, 20 (4), pp.1204-1212. ⟨10.1021/bp034301z⟩
Article dans une revue istex hal-02149856 v1

Bioartificial livers (BAL): current technological aspects and future developments

C. Legallais , B David , E. Dore
Journal of Membrane Science, 2001, 181 (1), pp.81-95. ⟨10.1016/S0376-7388(00)00539-1⟩
Article dans une revue istex hal-02149872 v1
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Triphasic electrospun scaffold with dynamic cells coculture for tissue engineering of bone-tendon-muscle junctions

Nicolas Rivoallan , Morgane Lagier , Timothée Baudequin , Marc Mueller , Pascale Vigneron et al.
ESAO-IFAO Congress, ESAO-IFAO, Sep 2024, Aachen (Aix la Chapelle), Germany. pp.421-565, ⟨10.1177/03913988241279540⟩
Communication dans un congrès hal-04754056 v1

Investigation of Oleic Acid, Palmitic Acid and their mixture on the development of hepatic steatosis using liver-on-chip technology

Lisa Morisseau , C. Legallais , Amar Abderrahmani , Yasuyoshi Sakai , Eric Leclerc et al.
49th ESAO Congress, Aug 2023, Bergamo, Italy
Communication dans un congrès hal-04476949 v1

Advancements towards artificial organs

C. Legallais
ESOT Congres, European Society for Orthotopic Transplantation, Sep 2023, Athènes, Greece
Communication dans un congrès hal-04583786 v1

Philosophy of science, a tool to face engineered liver challenges

M Guillet , U Pereira , C de Lartigue , C Legallais , X Guchet
Termis –EU 2022, Jun 2022, Krakow, Poland
Communication dans un congrès hal-04471738 v1
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Contrôle découlement et suivi de prolifération dans des biopuces hépatiques

Taha Messelmani , Adam Meziane , William César , Marine Verhulsel , Zied Souguir et al.
25`eme Congrès Français de Mécanique, Aug 2022, Nantes, France
Communication dans un congrès hal-04497647 v1

Membranes and Porous Scaffolds for Bioartificial Organs

C. Legallais
EuroMembrane 2022, Nov 2022, Sorrento (Italie), Italy
Communication dans un congrès hal-04475702 v1

Evaluation of treatment strategies for acute liver failure based on a perfused bed bioreactor

C de Lartigue , U Pereira , M Guillet , C Legallais
9th World Congress of Biomechanics, Jul 2022, Tai pei, Taiwan
Communication dans un congrès hal-04471743 v1

Development of liver-on-chip model integrating LSEC barrier and hepatocytes organoids for toxicity application

Taha Messelmani , Anne Le Goff , Fabrice Soncin , Zied Souguir , Elodie Vandenhaute et al.
The 1st edition of the MicroPhysio conference on "Micro-physiological models: From organoids to organs-on-chip", Apr 2022, Cargese (Corse), France
Communication dans un congrès hal-04497703 v1

Development of an advanced liver organ-on-chip integrating hydroscaffold mimicking cell matrix

Taha Messelmani , Zied Souguir , Victoria Maes , Anne Le Goff , Elodie Vandenhaute et al.
47th ESAO Congress, Sep 2021, London (U.K.), United Kingdom
Communication dans un congrès hal-04497725 v1

Modulating mechanical and biological parameters to investigate phenotypic changes in human liver sinusoidal endothelial cells

A Couderc , K El Kirat , P Moret , C Legallais , A Le Goff et al.
2021 TERMIS 6th World Congress, Nov 2021, Maastricht, Netherlands
Communication dans un congrès hal-04476517 v1

Can a new perfused dynamic bioreactor hosting heparg in alginate-poly-l-lysine beads meet the clinical needs for extracorporeal liver supply?

C de Lartigue , U Pereira , M Pasqua , J Nicolas , J Rialland et al.
47th ESAO congress, Sep 2021, London, United Kingdom
Communication dans un congrès hal-04471728 v1

3D liver-on-chip model integrating hydrogel mimicking cell matrix

Taha Messelmani , Zied Souguir , Victoria Maes , Anne Le Goff , Eric Leclerc et al.
TERMIS 6th World Congress, Nov 2021, Maastricht (Netherland), Netherlands
Communication dans un congrès hal-04500618 v1

Investigation of the Behavior of Rat Pancreatic Islets in an Organ-On-Chip Model

Amal Essaouiba , Teru Okitsu , Rachid Jellali , Marie Shinohara , Mathieu Danoy et al.
IFAO-JSAO Congress, Nov 2019, Osaka (JP), Japan
Communication dans un congrès hal-04475774 v1

The benefits of multiscale approaches in Liver Tissue Engineering

C. Legallais
46th Congress European Society for Artificial Organs, ESAO, Sep 2019, Hannover - Germany, Germany
Communication dans un congrès hal-04475719 v1

Ethical and epistemological questions in (bio)artificial organs

C. Legallais , X. Guchet
Joint IFAO-JSAO Congress, Japanese Society for Artificial Organs, Nov 2019, Osaka (JP), Japan
Communication dans un congrès hal-04583808 v1

Cryogel integrated microchip : towards a human 3D model of liver cancer

Lilandra Boulais , Rachid Jellali , Ulysse Pereira , Patrick Paullier , Eric Leclerc et al.
Cancer Cells-on-Chip 2, Mar 2019, Lyon, France
Communication dans un congrès hal-04475771 v1

Bioartificial liver : What’s next ?

C. Legallais
European Society for Orthotopic Transplantation (ESOT) Congress, Sep 2019, Copenaghen, Denmark
Communication dans un congrès hal-04475716 v1

Bioartificial Liver: What's next ?

C. Legallais
ESOT Congress, European Society for Orthotopic Transplantation, Sep 2019, Copenhagen, Denmark
Communication dans un congrès hal-04583832 v1

Liver on chip platform: key questions following 15 years of development

C. Legallais , Rachid Jellali , Eric Leclerc
International MicroNanoconference, Dec 2018, Amsterdam, Netherlands
Communication dans un congrès hal-04475722 v1

Electrically Conductive Multi Dimensional Scaffolds With Controllable Architecture For Skeletal Muscle Engineering

Megane Beldjilali-Labro , Alejandro Garcia Garcia , Fahmi Bedoui , Rachid Jellali , Murielle Dufresne et al.
5th TERMIS World Congress, Aug 2018, Kyoto (Japan), Japan
Communication dans un congrès hal-04475764 v1

Mechanical stimulation monitoring towards optimal tendon tissue reconstruction

Alejandro Garcia Garcia , Jean-Baptiste Perot , Marie Naudot , Sophie Le Ricousse , C. Legallais et al.
XLV ESAO Congress, Sep 2018, Madrid, Spain
Communication dans un congrès hal-04475768 v1

Development and validation of a bioartificial liver device with fluidized bed bioreactors hosting alginate-encapsulated hepatocyte spheroids

S. Figaro , Ulysse Pereira , H. Rada , N. Semenzato , D. Pouchoulin et al.
2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Aug 2015, Milan, France. pp.1335-1338, ⟨10.1109/embc.2015.7318615⟩
Communication dans un congrès hal-03411623 v1

Liver-kidney microfluidic bioreactor for cell co-culture in drug studies

L. Choucha Snouber , Laurent Griscom , Pe Poleni , Florence Razan , Céline Brochot et al.
MICROTAS, Oct 2010, GRONINGEN, Netherlands. pp.0328
Communication dans un congrès hal-00756580 v1
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Numerical study of the influence of wall compliance on the hemodynamics in a patient-specific arteriovenous fistula

Iolanda Decorato , Zaher Kharboutly , Cécile Legallais , Anne-Virginie Salsac
CFM 2011 - 20ème Congrès Français de Mécanique, Aug 2011, Besançon, France
Communication dans un congrès hal-03421275 v1

RFID implantable pressure sensor for the follow-up of abdominal aortic aneurysm stented

Olivier Romain , Johan Mazeyrat , Patrick Garda , Hakeim Talleb , David Lautru et al.
IEEE DTIS 2011 : 6th International conference on Design & Technology of Integrated Systems in nanoscale era, Apr 2011, Athens, Greece. pp.1-6, ⟨10.1109/DTIS.2011.5941418⟩
Communication dans un congrès hal-00600948 v1

Toxicologie predictive: les voies du futur

Ph Detilleux , L Vallier , C Legallais , E Leclerc , M Prot J et al.
Congrès de la SPTC - Société de Pharmaco-Toxicologie Cellulaire, May 2010, Paris, France
Communication dans un congrès hal-01122677 v1

Calibration of PBPK models based on in vivo and in vitro data to describe complex biotransformation processes

Dany Habka , Alexandre R.R. Pery , C. Aninat , A. Corlu , C. Guguen-Guillouzo et al.
12. International Congress of Toxicology (IUTOX 2010), Jul 2010, Barcelone, Spain
Communication dans un congrès ineris-00970650 v1

Microfluidic biochip for in vitro toxicity analysis

R. Baudoin , J.M. Prot , C. Legallais , E. Leclerc
ESAO 2009, Sep 2009, Compiègne, France
Communication dans un congrès hal-00456973 v1

Comparison of the growth kinetics of hepatocarcinoma cells in a microfluidic bioreactor and Petri dishes

J.M. Prot , R. Baudoin , L. Griscom , C. Legallais , E. Leclerc
MMB 2009, Apr 2009, Québec, Canada
Communication dans un congrès hal-00457134 v1

Use of a liver biochip as a tool in toxicological study.

J.M. Prot , R. Baudoin , L. Griscom , C. Legallais , E. Leclerc
XXXVI Annual meeting European Society for Artificial Organs. ESAO 2009, Sep 2009, Compiègne, France
Communication dans un congrès hal-00457136 v1

Flow and mass transfer modeling for tissue engineering applications.

B. Carpentier , A. Gautier , P. Paullier , A. Ould-Dris , P. Layrolle et al.
33ème Congrès de la Société de Biomécanique, Sep 2008, Compiègne, France. pp.53-55
Communication dans un congrès hal-00345817 v1

Bicarbonate and urea kinetics modeling during hemodialysis and online postdilution hemodiafiltration.

H. Morel , M.Y. Jaffrin , J. Vienken , C. Legallais
ESAO 2008, XXXV Annual Meeting European Society for Artificial Organs, Sep 2008, Genève, Switzerland. pp.65
Communication dans un congrès hal-00345030 v1

In vitro bicarbonate and urea kinetics during hemodialysis and online hemodiafiltration.

H. Morel , M.Y. Jaffrin , C. Legallais , J. Vienken
33ème Congrès de la Société de Biomécanique, Sep 2008, Compiègne, France. pp.167
Communication dans un congrès hal-00344995 v1

Cell Micro-Encapsulation and Bioartificial Liver.

C. Legallais , A. Gautier , B. Carpentier , Q. Vu Dinh , M. Dufresne et al.
8th World Biomaterials Congress, May 2008, Amsterdam, Netherlands
Communication dans un congrès hal-00345819 v1

Modélisations numérique et expérimentale des écoulements sanguins dans une fistule artério veineuse

Zaher Kharboutly , Cécile Legallais , Valérie Deplano , Eric Bertrand
8ème Colloque National en calcul des structures, May 2007, Giens, France
Communication dans un congrès hal-00455960 v1

Modélisations numérique et expérimentale des écoulements sanguins dans une fistule artério-veineuse.

Z. Kharboutly , C. Legallais , V. Deplano , E. Bertrand
8ème Colloque National en Calcul des Structures, May 2007, Giens, France
Communication dans un congrès hal-00294647 v1
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Modélisations numérique et expérimentale des écoulements sanguins dans une fistule artério-veineuse

Zaher Kharboutly , Cécile Legallais , Valérie Deplano , Eric Bertrand
8e Colloque national en calcul des structures, CSMA, May 2007, Giens, France
Communication dans un congrès hal-01507578 v1

Three dimensional growth of hepatic cells in alginate beads. Studies of beads optimization for fluidized bed bioreactor.

A. Kinasiewicz , A. Gautier , D. Lewinska , M. Dufresne , A. Smietanka et al.
34th ESAO Congress, Sep 2007, Krems, Austria
Communication dans un congrès hal-00290051 v1

An example of bioartificial organ : combination of hepatocytes microencapsulation and fluidized bed technology for extracorporeal liver support.

A. Gautier , M. Dufresne , B. Carpentier , P. Paullier , C. Legallais
International Congress on “Biochromatography and Nanobiotechnologies", Feb 2007, Vellore, India
Communication dans un congrès hal-00289993 v1

Bioartificial liver based on hollow fiber membrane : physical and biological characterization at micro scale level.

A. Gautier , H.D. Lemke , B. von Harten , M. Dufresne , C. Legallais
34th ESAO Congress, Sep 2007, Krems, Austria
Communication dans un congrès hal-00290030 v1

Development of a cellular biochip mimicking in vitro organs for chronic toxicity analysis.

R. Baudoin , L. Griscom , A. Corlu , P. Layrolle , C. Legallais et al.
Transducers'07, 14th International Conference on Solid-State Sensors, actuators and Microsystems, Jun 2007, Lyon, France
Communication dans un congrès hal-00289965 v1
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Validation des procédures de maillage pour l'étude des écoulements sanguins dans une fistule artério-veineuse réelle

Zaher Kharboutly , J.M. Treutenaere , I. Claude , M. Fenech , C. Legallais
CFM 2007 - 18ème Congrès Français de Mécanique, Aug 2007, Grenoble, France
Communication dans un congrès hal-03360384 v1

Caractérisation des écoulements dans une fistule artério veineuse. Comparaison numérique expérimentale.

Zaher Kharboutly , Cécile Legallais , Eric Bertrand , Valérie Deplano
Journées scientifiques du GDR2760 : Interactions fluide structure biologiques, May 2007, Marseille, France
Communication dans un congrès hal-00456057 v1

Production of bone substitutes in bioreactors : Modeling and culture of bone marrow stem cells.

B. Carpentier , J. Sohier , P. Layrolle , C. Legallais
34th ESAO Congress, Sep 2007, Krems, Austria
Communication dans un congrès hal-00289975 v1

Human liver cells in a pilot-scale fluidised-bed bioreactor maintain performance in human liver failure plasma making them suitable for a bioartificial liver.

S. Coward , C. Legallais , A. Gautier , P. Paullier , M. Thomas et al.
5th World Congress of Biomechanics, Jul 2006, Munich, Germany
Communication dans un congrès hal-00118127 v1

PDMS microdevices as new supports for in vitro bioartificial organs.

R. Baudoin , L. Griscom , C. Legallais , E. Leclerc
XXXIII ESAO Congress, Jun 2006, Umea, Sweden
Communication dans un congrès hal-00116600 v1

Development of a renal microfluidic device for future in vitro kidney model reconstruction.

R. Baudoin , L. Griscom , C. Legallais , E. Leclerc
XXXIII ESAO Congress, Jun 2006, Umea, Sweden
Communication dans un congrès hal-00116598 v1

Application of cells microencapsulation for bioartificial liver in fluidized bed bioreactor.

A. Gautier , B. Carpentier , M. Dufresne , P. Paullier , C. Legallais
14th International Workshop on Bioencapsulation, Oct 2006, Lausanne, Switzerland
Communication dans un congrès hal-00118146 v1

Liver organotypic chick embryo cultures on silicone microchannels.

E. Leclerc , A. Corlu , L. Griscom , R. Baudoin , C. Legallais
ESB 20th European Conference on Biomaterials, Sep 2006, Nantes, France
Communication dans un congrès hal-00118400 v1

Mass transfer studies in a model of fluidized bed bioartificial liver.

B. Carpentier , A. Gautier , P. Paullier , C. Legallais
XXXIII ESAO Congress, Jun 2006, Umea, Sweden
Communication dans un congrès hal-00118114 v1

Activity of cells within alginate beads produced for fluidized bed bioreactor (bioartificial liver).

A. Kinasiewicz , A. Gautier , D. Lewinska , M. Dufresne , P. Paullier et al.
XXIII ESAO Congress, Jun 2006, Umea, Sweden
Communication dans un congrès hal-00118286 v1

Development of a microfluidic devices for in vitro liver model.

R. Baudoin , L. Griscom , A. Corlu , C. Legallais , E. Leclerc
5th World Congress of Biomechanics, Jul 2006, Munich, Germany
Communication dans un congrès hal-00116596 v1

In vitro optimization of alginate bead production for hepatocytes encapsulation in the fluidized bed bioartificial liver.

A. Gautier , A. Kinasiewicz , B. Carpentier , D. Lewinska , P. Paullier et al.
5th World Congress of Biomechanics, Jul 2006, Munich, Germany
Communication dans un congrès hal-00118148 v1

Numerical Simulation of Blood Flow in a side-to-end fistula for hemodialysis.

Z. Kharboutly , J.M. Treutenaere , M. Fenech , T. Chambon , I. Claude et al.
5th World Congress of Biomechanics, Jul 2006, Munich, Germany
Communication dans un congrès hal-00118280 v1

Investigation of Human Hepatoma cell line microfluidic devices.

E. Leclerc , L. Griscom , Bruno Le Pioufle , C. Guguen-Guillouzo , A. Corlu et al.
3rd annual International IEEE EMBS special topic conference on microtechnologies in medicine and biology., 2005, Oahu, Hawaii, United States
Communication dans un congrès hal-00019381 v1

Blood flow simulation in an arteriovenous fistula.

Z. Kharboutly , M. Fenech , J.M. Treutenaere , I. Claude , C. Legallais
XXth Congress International Society for Biomechanics, 2005, Cleveland, Ohio, United States
Communication dans un congrès hal-00019375 v1

CFD modeling of unsteady blood flow in a arteriovenous fistula reconstructed from angioscanner.

Z. Kharboutly , M. Fenech , J.M. Treutenaere , I. Claude , C. Legallais
30ème Congrès de la Société de Biomécanique. In Computer Methods in Biomechanics and Biomedical Engineering, 8,, 2005, Bruxelles, Belgium. pp.161-162
Communication dans un congrès hal-00019374 v1

Behaviour of osteoblast-like cells in cellular microdevices

E. Leclerc , B. David , R. Warocquier-Clerout , L. Griscom , Bruno Le Pioufle et al.
Micro Total Analysis Systems 2004, Vol 1, 2005, Netherlands. pp.396-398
Communication dans un congrès hal-00795188 v1

Hydrodynamic behaviour of several types of fluidized bed bioreactor used in a bioartificial liver.

R. Baudoin , A. Gautier , S.M. Coward , B. David , H.J.F. Hodgson et al.
XXXII ESAO Congress, 2005, Bologne, Italy
Communication dans un congrès hal-00018719 v1

Non woven electrospun scaffold with continuous gradient from honeycomb like to aligned structures for osteotendinous junction tissue engineering

Nicolas Rivoallan , Timothée Baudequin , Birgit Glasmacher , C. Legallais
49th ESAO congress, Aug 2023, Bergamo, Italy
Poster de conférence hal-04476951 v1

What is a biologically inspired human-designed liver?[

M Guillet , U Pereira , C de Lartigue , C Legallais , X Guchet
6th World congress Termis 2021, Nov 2021, Maasticht, Netherlands
Poster de conférence hal-04471715 v1

Evaluation of treatment strategies for acute liver failure based on a perfused bed bioreactor

C de Lartigue , U Pereira , M Pasqua , J Nicolas , J Rialland et al.
6th World congress Termis 2021, Nov 2021, Maasticht, Netherlands
Poster de conférence hal-04471720 v1

Activity of encapsulated HepaRG in fluidized bed artificial liver

C de Lartigue , M Pasqua , U Pereira , C Legallais
Biomat – MatSan, Jun 2019, La grande Motte, France
Poster de conférence hal-04471634 v1

Can HepaRG self-assembled spheroids fulfil the clinical needs for extracorporeal liver supply?

M Pasqua , U Pereira , A Messina , C de Lartigue , P Vigneron et al.
3D culture to organoids, Dec 2019, Paris, France
Poster de conférence hal-04471643 v1

Can encapsulated HEPARG in alginate-polyl-lysine beads meet the clinical needs for extracorporeal liver supply?

M Pasqua , U Pereira , C de Lartigue , A Messina , P Vigneron et al.
3D culture to organoids, Dec 2019, Paris, France
Poster de conférence hal-04471711 v1

Differentiation of human pluripotent stem cells into hepatocytes is more efficient in spheroids than in 2D culture

A Messina , U Pereira , C Legallais , A Dubart-Kupperschmitt
EASL the international liver congress, Oct 2018, Paris ( France), France
Poster de conférence hal-04471493 v1

Cryogel-integrated hepatic cell culture microchips for liver tissue engineering

L Boulais , R Jellali , U Pereira , P Paullier , E Leclerc et al.
Termis world congres Kyoto, Sep 2018, Kyoto (Japan), Japan
Poster de conférence hal-04471609 v1
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Microfluidic and Organ-on-a-chip-based Technologies for Diabetes Therapy and Research

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