Cécile Denis

Publications

Article dans une revue (99)

Magnetostaltic pumping in an ex vivo extracorporeal membrane oxygenation model Mohammadreza Zolala,Veronique Heim,Cécile V Denis,Peter J Lenting,Pierre H. Manginet al. Journal of Translational Medicine, 2026, 24 (1), pp.252. ⟨10.1186/s12967-026-07734-w⟩ Article dans une revue hal-05536643v1
Total Thrombus Formation system exploration of primary haemostasis in cirrhotic patients Johan Abdoul,Norman Luc,Bérangère Joly,Antoine Jehl,Adeline Blandinièreset al. Research and Practice in Thrombosis and Haemostasis, 2026, pp.103370. ⟨10.1016/j.rpth.2026.103370⟩ Article dans une revue hal-05487282v1
A fully humanized von Willebrand disease type 1 mouse model as unique platform to investigate novel therapeutic options Geneviève Mccluskey,Marco Heestermans,Ivan Peyron,Eloise Pascal,Marie Clavelet al. Haematologica, In press, ⟨10.3324/haematol.2024.286076⟩ Article dans une revue (data paper) hal-04871911v1
F-actin disassembly by the oxidoreductase MICAL1 promotes mechano-dependent VWF-GPIbα interaction in platelets Jean Solarz,Christelle Soukaseum,Stéphane Frémont,Sébastien Eymieux,Camilia Nabliet al. Nature Communications, 2025, 16 (1), pp.7375. ⟨10.1038/s41467-025-62487-2⟩ Article dans une revue hal-05206235v2
Clinical, Phenotypic and Genotypic Characteristics of Von Willebrand Disease in Afro‐Caribbeans: Results From a Study in Martinique Island, French West Indies Marie‐daniéla Dubois,Olivier Nicolas Pierre-Louis,Serge Pierre-Louis,Pierre Boisseau,Cécile Deniset al. Haemophilia, 2025, ⟨10.1111/hae.70003⟩ Article dans une revue hal-05045740v1
A consistent clinical factor VIII-equivalence is unlikely to exist for non-factor therapies in hemophilic mice Thibaud Sefiane,Geneviève Mccluskey,Marie Clavel,Hortense Maynadié,Ivan Peyronet al. Haematologia, In press, ⟨10.3324/haematol.2024.286982⟩ Article dans une revue hal-05051687v1
Clinical, Phenotypic and Genotypic Characteristics of Von Willebrand Disease in Afro‐Caribbeans: Results From a Study in Martinique Island, French West Indies Marie‐daniéla Dubois,Olivier Nicolas Pierre-Louis,Serge Pierre-Louis,Pierre Boisseau,Cécile Deniset al. Haemophilia, 2025, 31 (3), pp.458-476. ⟨10.1111/hae.70003⟩ Article dans une revue hal-05306019v1
A bispecific nanobody for the treatment of von Willebrand disease type 1 Ivan Peyron,Caterina Casari,Geneviève Mccluskey,Stéphanie Roullet,Vincent Licariet al. Blood, 2025, ⟨10.1182/blood.2025029401⟩ Article dans une revue hal-05263486v1
Amelioration of a von Willebrand disease type 2B phenotype in vivo upon treatment with allele-selective siRNAs Noa Linthorst,Yvonne Jongejan,Richard Dirven,Sebastiaan Laan,Ruben Bieringset al. Blood Advances, 2025, 9 (2), pp.310-320. ⟨10.1182/bloodadvances.2024014601⟩ Article dans une revue hal-05045746v1
NF-κB-Mediated Upregulation of Tissue Factor Contributes to the Procoagulant Phenotype of Smooth Muscle Cells from Abdominal Aorta Aneurysm in Human Veronique Regnault,Melusine Didelot,Veronique Ollivier,Cécile Lakomy,Jeremy Lagrangeet al. Thrombosis and Haemostasis, 2025, 126 (3), pp.319-331. ⟨10.1055/a-2665-2510⟩ Article dans une revue hal-05562634v1
Thrombin cleaves membrane-bound endoglin potentially contributing to the heterogeneity of circulating endoglin in preeclampsia Divina El Hamaoui,Aurore Marchelli,Sophie Gandrille,Etienne Reboul,Alain Stepanianet al. Communications Biology, 2025, 8 (1), pp.316. ⟨10.1038/s42003-025-07751-3⟩ Article dans une revue hal-04970186v1
Rôles du facteur von Willebrand dans les maladies inflammatoires chronique de l'intestin Jérémy Lagrange,Muhammad Usman Ahmed,Djésia Arnone,Patrick Lacolley,Véronique Regnaultet al. Sang Thrombose Vaisseaux, 2024, 36 (4), pp.159-170. ⟨10.1684/stv.2024.1293⟩ Article dans une revue (article de synthèse) hal-05150181v1
Von Willebrand factor: how unique structural adaptations support and coordinate its complex function Peter J. Lenting,Cécile Denis,Olivier Christophe Blood, 2024, 144 (21), pp.2174-2184. ⟨10.1182/blood.2023023277⟩ Article dans une revue hal-04817254v1
Differences in venous clot structures between hemophilic mice treated with emicizumab versus factor VIII or factor VIIIFc Thibaud Sefiane,Hortense Maynadié,Carmen Escurola Ettingshausen,Vincent Muczynski,Xavier Heiligensteinet al. Haematologica, 2024, ⟨10.3324/haematol.2023.284142⟩ Article dans une revue hal-04449388v1
An Inhibitory Single-Domain Antibody against Protein Z-Dependent Protease Inhibitor Promotes Thrombin Generation in Severe Hemophilia A and FXI Deficiency Claire Auditeau,Tung-Son Nguyen,Floriane Devaux,François Saller,Ivan Peyronet al. Thrombosis and Haemostasis, 2024, 125 (03), pp.207-217. ⟨10.1055/a-2373-2829⟩ Article dans une revue hal-05316627v1
The Role of Platelets and von Willebrand Factor in the Procoagulant Phenotype of Inflammatory Bowel Disease Célia Schellenberg,Jérémy Lagrange,Muhammad Usman Ahmed,Djésia Arnone,Philippe Campoliet al. Journal of Crohn's and Colitis, 2024, 18 (5), pp.751-761. ⟨10.1093/ecco-jcc/jjad198⟩ Article dans une revue hal-04458197v1
Type 2N von Willebrand disease: Genotype drives different bleeding phenotypes and treatment needs Mélanie Daniel,Catherine Ternisien,Sabine Castet,Céline Falaise,Roseline D’oironet al. Journal of Thrombosis and Haemostasis, 2024, ⟨10.1016/j.jtha.2024.06.020⟩ Article dans une revue hal-04665358v1
Impact of allele-selective silencing of von Willebrand factor in mice based on a single nucleotide allelic difference in von Willebrand factor Yvonne Jongejan,Noa Linthorst,Elisa Schrader Echeverri,Sebastiaan N.J. Laan,Richard Dirvenet al. Thrombosis Research, 2024, 236, pp.201-208. ⟨10.1016/j.thromres.2024.03.002⟩ Article dans une revue hal-04559129v1
A small-molecule hemostatic agent for the reversal of direct oral anticoagulant–induced bleeding Maximilien Desvages,Delphine Borgel,Frédéric Adam,Ge Tu,Simon Jaouenet al. Research and Practice in Thrombosis and Haemostasis, 2024, 8 (4), pp.102426. ⟨10.1016/j.rpth.2024.102426⟩ Article dans une revue hal-04927372v1
von Willebrand disease Omid Seidizadeh,Jeroen Eikenboom,Cécile Denis,Veronica Flood,Paula Jameset al. Nature Reviews Disease primers, 2024, 10 (1), pp.51. ⟨10.1038/s41572-024-00536-8⟩ Article dans une revue hal-04665350v1
Thrombin generation on vascular cells in the presence of factor VIII and/or emicizumab Sénadé Atsou,Célia Schellenberg,Jeremy Lagrange,Patrick Lacolley,Peter Lentinget al. Journal of Thrombosis and Haemostasis, 2024, 22 (1), pp.112-125. ⟨10.1016/j.jtha.2023.09.017⟩ Article dans une revue hal-04449373v1
Implications of von Willebrand Factor in Inflammatory Bowel Diseases: Beyond Bleeding and Thrombosis Jérémy Lagrange,Muhammad Usman Ahmed,Djésia Arnone,Patrick Lacolley,Véronique Regnaultet al. Inflammatory Bowel Diseases, 2024, 30 (12), pp.2500-2508. ⟨10.1093/ibd/izae142⟩ Article dans une revue hal-04701011v1
Fitusiran reduces bleeding in factor X–deficient mice Sebastien Verhenne,Geneviève Mccluskey,Hortense Maynadié,Frédéric Adam,Caterina Casariet al. Blood, 2024, 144 (2), pp.227-236. ⟨10.1182/blood.2023023404⟩ Article dans une revue hal-04654300v1
Angiopoietin-2 binds to multiple interactive sites within von Willebrand factor Alexis Texier,Peter Lenting,Cécile Denis,Stéphanie Roullet,Olivier Christophe Research and Practice in Thrombosis and Haemostasis, 2023, HITH, 7 (7), pp.102204. ⟨10.1016/j.rpth.2023.102204⟩ Article dans une revue (data paper) hal-04449394v1
Transplacental delivery of therapeutic proteins by engineered IgG: a step towards perinatal replacement therapy Angelina Mimoun,Melissa Bou Jaoudeh,Sandrine Delignat,Victoria Daventure,Alejandra Reyes Ruizet al. Journal of Thrombosis and Haemostasis, In press, ⟨10.1016/j.jtha.2023.05.021⟩ Article dans une revue hal-04117814v1
Imlifidase, a new option to optimize the management of patients with hemophilia A on emicizumab Melissa Bou-Jaoudeh,Angelina Mimoun,Sandrine Delignat,Ivan Peyron,Ladislas Capdevilaet al. Journal of Thrombosis and Haemostasis, 2023, 21 (10), pp.2776-2783. ⟨10.1016/j.jtha.2023.06.038⟩ Article dans une revue hal-04217783v1
A nanobody against the VWF A3 domain detects ADAMTS13-induced proteolysis in congenital and acquired VWD Claire Kizlik-Masson,Ivan Peyron,Stéphane Gangnard,Gaelle Le Goff,Solen Lenoiret al. Blood, 2023, 141 (12), pp.1457-1468. ⟨10.1182/blood.2022017569⟩ Article dans une revue inserm-04258451v1
Modèles murins en hémostase Cécile Denis,Caterina Casari,Stéphanie Roullet Hématologie, 2023, 29 (6), pp.338-353. ⟨10.1684/hma.2023.1827⟩ Article dans une revue (article de synthèse) hal-04457009v1
MAGT1 deficiency in XMEN disease is associated with severe platelet dysfunction and impaired platelet glycoprotein N-glycosylation Alexandre Kauskot,Coralie Mallebranche,Arnaud Bruneel,François Fenaille,Jean Solarzet al. Journal of Thrombosis and Haemostasis, 2023, ⟨10.1016/j.jtha.2023.05.007⟩ Article dans une revue hal-04106364v1
Shear Force-Induced Platelet Clearance Is a New Mechanism of Thrombocytopenia Antoine Rauch,Annabelle Dupont,Mickael Rosa,Maximilien Desvages,Christina Le Tannoet al. Circulation Research, 2023, 133 (10), pp.826-841. ⟨10.1161/CIRCRESAHA.123.322752⟩ Article dans une revue hal-04455871v1
ADP receptor P2Y12 is the capstone of the cross-talk between Ca 2+ mobilization pathways dependent on ATPases SERCA3 and SERCA2b in platelet Miao Feng,Béatrice Hechler,Frédéric Adam,Christian Gachet,Anita Ecklyet al. Research and Practice in Thrombosis and Haemostasis, In press Article dans une revue (data paper) hal-03930689v1
Development of a dual hybrid AAV vector for endothelial-targeted expression of von Willebrand factor Elena Barbon,Charlotte Kawecki,Solenne Marmier,Aboud Sakkal,Fanny Collaudet al. Gene Therapy, 2023, 30 (3-4), pp.245-254. ⟨10.1038/s41434-020-00218-6⟩ Article dans une revue hal-04455812v1
Efficacy of platelet-inspired hemostatic nanoparticles on bleeding in Von Willebrand disease murine models Stéphanie Roullet,Norman Luc,Julie Rayes,Jean Solarz,Dante Disharoonet al. Blood, 2023, 141 (23), pp.2891-2900. ⟨10.1182/blood.2022018956⟩ Article dans une revue inserm-04066466v1
N-Glycosylation Deficiency Reduces the Activation of Protein C and Disrupts Endothelial Barrier Integrity Tiffany Pascreau,François Saller,Elsa Bianchini,Dominique Lasne,Arnaud Bruneelet al. Thrombosis and Haemostasis, 2022, 122 (09), pp.1469-1478. ⟨10.1055/s-0042-1744378⟩ Article dans une revue inserm-04455209v1
The VWF/LRP4/aVb3-axis represents a novel pathway regulating proliferation of human vascular smooth muscle cells Jérémy Lagrange,Morel Worou,Jean-Baptiste Michel,Alexandre Raoul,Mélusine Didelotet al. Cardiovascular Research, 2022, 118 (2), pp.622-637. ⟨10.1093/cvr/cvab042⟩ Article dans une revue hal-03267669v1
Identification of von Willebrand factor D4 domain mutations in patients of Afro‐Caribbean descent: In vitro characterization Marie‐daniéla Dubois,Ivan Peyron,Olivier‐nicolas Pierre-Louis,Serge Pierre-Louis,Johalène Raboutet al. Research and Practice in Thrombosis and Haemostasis, 2022, 6 (4), pp.e12737. ⟨10.1002/rth2.12737⟩ Article dans une revue hal-04354187v1
New insights into regulation of αIIbβ3 integrin signaling by filamin A Lamia Lamrani,Frédéric Adam,Christelle Soukaseum,Cécile Denis,Hana Raslovaet al. Research and Practice in Thrombosis and Haemostasis, 2022, 6 (2), pp.e12672. ⟨10.1002/rth2.12672⟩ Article dans une revue hal-04471560v1
TaSER: Combining forces to stop the clot Cécile Denis,Peter Lenting,Denis Wahl Journal of Thrombosis and Haemostasis, 2022, HITH, 20 (2), pp.293-295. ⟨10.1111/jth.15597⟩ Article dans une revue hal-04449115v1
Antithrombotic potential of a single‐domain antibody enhancing the activated protein C‐cofactor activity of protein S Josepha Sedzro,Frédéric Adam,Claire Auditeau,Elsa Bianchini,Allan de Carvalhoet al. Journal of Thrombosis and Haemostasis, 2022, 20 (7), pp.1653-1664. ⟨10.1111/jth.15736⟩ Article dans une revue inserm-04455219v1
A gain‐of‐function filamin A mutation in mouse platelets induces thrombus instability Frédéric Adam,Alexandre Kauskot,Lamia Lamrani,Jean Solarz,Christelle Soukaseumet al. Journal of Thrombosis and Haemostasis, 2022, 20 (11), pp.2666-2678. ⟨10.1111/jth.15864⟩ Article dans une revue hal-03896872v1
Identification of von Willebrand factor D4 domain mutations in patients of Afro‐Caribbean descent: In vitro characterization Marie‐daniéla Dubois,Ivan Peyron,Olivier‐nicolas Pierre-Louis,Serge Pierre-Louis,Johalène Raboutet al. Research and Practice in Thrombosis and Haemostasis, 2022, 6 (4), pp.e12737. ⟨10.1002/rth2.12737⟩ Article dans une revue hal-05306074v1
A thrombopoietin receptor agonist to rescue an unusual platelet transfusion-induced reaction in a p.V1316M-associated von Willebrand disease type 2B patient Caterina Casari,Remi Favier,Paulette Legendre,Alexandre Kauskot,Frederic Adamet al. Therapeutic Advances in Hematology, 2022, 13, pp.204062072210768. ⟨10.1177/20406207221076812⟩ Article dans une revue hal-04455865v1
Von Willebrand factor and cancer: Another piece of the puzzle Cécile V Denis,Stéphanie Roullet,Julien Perrin Journal of Thrombosis and Haemostasis, 2022, 20 (10), pp.2207-2210. ⟨10.1111/jth.15810⟩ Article dans une revue inserm-03783811v1
A compact integrated microfluidic oxygenator with high gas exchange efficiency and compatibility for long-lasting endothelialization Julie Lachaux,Gilgueng Hwang,Nassim Arouche,Sina Naserian,Abdelmounaim Harouriet al. Lab on a Chip, In press, ⟨10.1039/d1lc00356a⟩ Article dans une revue hal-03318488v1
The Proteolytic Inactivation of Protein Z-Dependent Protease Inhibitor by Neutrophil Elastase Might Promote the Procoagulant Activity of Neutrophil Extracellular Traps in Sepsis Elsa P Bianchini,Mahita Razanakolona,Julie Helms,Fouzia Zouiti,Amélie Couteau-Chardonet al. Thrombosis and Haemostasis, 2021, Online ahead of print. ⟨10.1055/a-1530-3980⟩ Article dans une revue inserm-03313257v1
Development of a dual hybrid AAV vector for endothelial-targeted expression of von Willebrand factor Elena Barbon,Charlotte Kawecki,Solenne Marmier,Aboud Sakkal,Fanny Collaudet al. Gene Therapy, 2021, 30 (3-4), pp.245-254. ⟨10.1038/s41434-020-00218-6⟩ Article dans une revue (data paper) hal-04324328v1
A compact integrated microfluidic oxygenator with high gas exchange efficiency and compatibility for long-lasting endothelialization Julie Lachaux,Gilgueng Hwang,Nassim Arouche,Sina Naserian,Abdelmounaim Harouriet al. Lab on a Chip, 2021, 21 (24), pp.4791-4804. ⟨10.1039/d1lc00356a⟩ Article dans une revue hal-03853585v1
How to keep the factor VIII/von Willebrand factor complex in the circulation Cécile Denis,Peter Lenting Haematologica, 2021, HITH, 107 (9), pp.2011-2013. ⟨10.3324/haematol.2021.280222⟩ Article dans une revue hal-04449734v1
Von Willebrand Disease: What does the future hold? Cécile V Denis,Sophie Susen,Peter J. Lenting Blood, 2021, 137 (17), pp.2299-2306. ⟨10.1182/blood.2020008501⟩ Article dans une revue hal-03267627v1
A Combination of Two Variants p. (Val510 =) and p. (Pro2145Thrfs * 5), Responsible for von Willebrand Disease Type 3 in a Caribbean Patient Marie Daniela Dubois,Serge Pierre-Louis,Johalène Rabout,Cécile Denis,Olivier Christopheet al. TH Open : Companion Journal To Thrombosis and Haemostasis, 2020, 04 (04), pp.e318-e321. ⟨10.1055/s-0040-1718703⟩ Article dans une revue hal-04683162v1
Camelid‐derived single‐chain antibodies in hemostasis: Mechanistic, diagnostic, and therapeutic applications Ivan Peyron,Claire Kizlik-Masson,Marie-Daniéla Dubois,Sénadé Atsou,Stephen Ferrièreet al. Research and Practice in Thrombosis and Haemostasis, 2020, 4 (7), pp.1087-1100. ⟨10.1002/rth2.12420⟩ Article dans une revue hal-05320380v1
A Combination of Two Variants p. (Val510 =) and p. (Pro2145Thrfs * 5), Responsible for von Willebrand Disease Type 3 in a Caribbean Patient Marie Daniela Dubois,Serge Pierre-Louis,Johalène Rabout,Cécile Denis,Olivier Christopheet al. TH Open : Companion Journal To Thrombosis and Haemostasis, 2020, 04 (04), pp.e318-e321. ⟨10.1055/s-0040-1718703⟩ Article dans une revue hal-05320384v1
In vivo modulation of a dominant‐negative variant in mouse models of von Willebrand disease type 2A Matteo Campioni,Paulette Legendre,Cécile Loubiere,Barbara Lunghi,Mirko Pinottiet al. Journal of Thrombosis and Haemostasis, 2020, Online ahead of print. ⟨10.1111/jth.15131⟩ Article dans une revue (data paper) inserm-02983110v1
A hemophilia A mouse model for the in vivo assessment of emicizumab function Stephen Ferrière,Ivan Peyron,Olivier D. Christophe,Charlotte Kawecki,Caterina Casariet al. Blood, 2020, 136 (6), pp.740-748. ⟨10.1182/blood.2019004334⟩ Article dans une revue inserm-02916896v1
Measuring beta‐galactose exposure on platelets: Standardization and healthy reference values Dominique Lasne,Tiffany Pascreau,Sadyo Darame,Marie‐charlotte Bourrienne,Peggy Tournouxet al. Research and Practice in Thrombosis and Haemostasis, 2020, 4 (5), pp.813-822. ⟨10.1002/rth2.12369⟩ Article dans une revue hal-02964593v1
Development and characterization of single‐domain antibodies neutralizing protease nexin‐1 as tools to increase thrombin generation Charlotte Kawecki,Karen Aymonnier,Stephen Ferrière,Laurence Venisse,Véronique Arocaset al. Journal of Thrombosis and Haemostasis, 2020, 18, pp.2155-2168. ⟨10.1111/jth.14940⟩ Article dans une revue inserm-02934843v1
NAADP/SERCA3-dependent Ca2+ stores pathway specifically controls early autocrine ADP secretion potentiating platelet activation. Miao Feng,Ziane Elaïb,Delphine Borgel,Cécile Denis,Frédéric Adamet al. Circulation Research, 2020, 127 (7), pp.e166-e183. ⟨10.1161/CIRCRESAHA.119.316090⟩ Article dans une revue inserm-02948394v1
Camelid‐derived single‐chain antibodies in hemostasis: Mechanistic, diagnostic, and therapeutic applications Ivan Peyron,Claire Kizlik‐masson,Marie‐daniéla Dubois,Sénadé Atsou,Stephen Ferrièreet al. Research and Practice in Thrombosis and Haemostasis, 2020, 4 (7), pp.1087-1110. ⟨10.1002/rth2.12420⟩ Article dans une revue hal-03116405v1
A Combination of Two Variants p. (Val510 =) and p. (Pro2145Thrfs * 5), Responsible for von Willebrand Disease Type 3 in a Caribbean Patient Marie Daniela Dubois,Serge Pierre-Louis,Johalène Rabout,Cécile Denis,Olivier Christopheet al. TH Open : Companion Journal To Thrombosis and Haemostasis, 2020, 04 (04), pp.e318-e321. ⟨10.1055/s-0040-1718703⟩ Article dans une revue hal-05306098v1
The von Willebrand Factor A1 domain mediates thromboinflammation, aggravating ischemic stroke outcome in mice Frederik Denorme,Kimberly Martinod,Aline Vandenbulcke,Cecile Denis,Peter J. Lentinget al. Haematologica, 2020, pp.haematol.2019.241042. ⟨10.3324/haematol.2019.241042⟩ Article dans une revue inserm-02552320v1
Gain-of-Function Variant p.Pro2555Arg of von Willebrand Factor Increases Aggregate Size through Altering Stem Dynamics Volker Huck,Po-Chia Chen,Emma-Ruoqi Xu,Alexander Tischer,Ulrike Klemmet al. Thrombosis and Haemostasis, 2020, 122 (02), pp.226-239. ⟨10.1055/a-1344-4405⟩ Article dans une revue (data paper) hal-04496009v1
Monoclonal gammopathy of clinical significance: &lt;i&gt;in vivo&lt;/i&gt; demonstration of the anti-thrombotic effect of an acquired anti-thrombin antibody Berenice Schell,Celine Desconclois,Xavier Mariette,Cecile Goujard,Peter Lentinget al. Haematologica, 2020, 106 (1), pp.316-319. ⟨10.3324/haematol.2019.242370⟩ Article dans une revue hal-04456957v1
A Combination of Two Variants p. (Val510 =) and p. (Pro2145Thrfs * 5), Responsible for von Willebrand Disease Type 3 in a Caribbean Patient Marie Daniela Dubois,Marie Daniela Dubois,Serge Pierre-Louis,Johalène Rabout,Cécile Deniset al. TH Open, 2020, 04 (04), pp.e318-e321. ⟨10.1055/s-0040-1718703⟩ Article dans une revue hal-03121861v1
Platelet Functions are Decreased in Obesity and Restored after Weight Loss: Evidence for a Role of the SERCA3-Dependent ADP Secretion Pathway Ziane Elaïb,Jose Lopez,Muriel Coupaye,Kevin Zuber,Yann Beckeret al. Thrombosis and Haemostasis, 2019, 119 (03), pp.384-396. ⟨10.1055/s-0038-1677033⟩ Article dans une revue hal-04453727v1
Endothelial-driven increase in plasma thrombin generation characterising a new hypercoagulable phenotype in acute heart failure Batric Popovic,Faiez Zannad,Huguette Louis,Isabelle Clerc-Urmès,Cécile Lakomyet al. International Journal of Cardiology, 2019, 274, pp.195-201. ⟨10.1016/j.ijcard.2018.07.130⟩ Article dans une revue istex hal-01944277v1
Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease: preclinical and clinical evidence Annabelle Dupont,Christelle Soukaseum,Mathilde Cheptou,Frédéric Adam,Thomas Nipotiet al. Haematologica, 2019, HITH, pp.haematol.2018.206250. ⟨10.3324/haematol.2018.206250⟩ Article dans une revue hal-02347340v1
Correction of bleeding in experimental severe hemophilia A by systemic delivery of factor VIII- encoding mRNA Jules Russick,Sandrine Delignat,Peter Milanov,Olivier D. Christophe,Gábor Boroset al. Haematologica, 2019, 105 (4), pp.1129-1137. ⟨10.3324/haematol.2018.210583⟩ Article dans une revue hal-02328193v1
Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor Emma-Ruoqi Xu,Sören von Bülow,Po-Chia Chen,Peter Lenting,Katra Kolšeket al. Blood, 2019, 133 (4), pp.366-376. ⟨10.1182/blood-2018-04-843615⟩ Article dans une revue hal-04456916v1
Vascular endothelial cell expression of JAK2V617F is sufficient to promote a pro-thrombotic state due to increased P-selectin expression Alexandre Guy,Virginie Gourdou-Latyszenok,Nicolas Le Lay,Claire Peghaire,Badr Kilaniet al. Haematologica, In press, 104 (1), pp.70-81. ⟨10.3324/haematol.2018.195321⟩ Article dans une revue hal-02995532v1
A single‐domain antibody that blocks factor VIIa activity in the absence but not presence of tissue factor Stephen Ferrière,Charlotte Kawecki,Jean‐françois Ottavi,Cécile Denis,Alexandre Kauskotet al. Journal of Thrombosis and Haemostasis, 2019, 17 (12), pp.2035-2046. ⟨10.1111/jth.14615⟩ Article dans une revue hal-04456634v1
A Thrombin-Activatable Factor X Variant Corrects Hemostasis in a Mouse Model for Hemophilia A Vincent Muczynski,Sebastien Verhenne,Caterina Casari,Ghislaine Chérel,Laurence Panicot-Duboiset al. Thrombosis and Haemostasis, 2019, 119 (12), pp.1981-1993. ⟨10.1055/s-0039-1697662⟩ Article dans une revue hal-02570572v1
Weibel-Palade Bodies Orchestrate Pericytes During Angiogenesis Mélissande Cossutta,Marie Darche,Gilles Carpentier,Claire Houppe,Matteo Ponzoet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2019, 39 (9), pp.1843-1858. ⟨10.1161/ATVBAHA.119.313021⟩ Article dans une revue hal-02347222v1
Vascular endothelial cell expression of JAK2 V617F is sufficient to promote a pro-thrombotic state due to increased P-selectin expression Alexandre Guy,Virginie Gourdou-Latyszenok,Nicolas Le Lay,Claire Peghaire,Badr Kilaniet al. Haematologica, 2019, 104 (1), pp.70-81. ⟨10.3324/haematol.2018.195321⟩ Article dans une revue hal-04477310v1
Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity Alessandro Donada,Nathalie Balayn,Dominika Sliwa,Larissa Lordier,Valentina Cegliaet al. Blood, 2019, 133 (16), pp.1778-1788. ⟨10.1182/blood-2018-07-861427⟩ Article dans une revue hal-04441275v1
The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction Reinhard Schneppenheim,Natalie Hellermann,Maria Brehm,Ulrike Klemm,Tobias Obseret al. Blood, 2019, 133 (4), pp.356-365. ⟨10.1182/blood-2018-04-843425⟩ Article dans une revue hal-04456911v1
Targeting protease nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia Karen Aymonnier,Charlotte Kawecki,Laurence Venisse,Yacine Boulaftali,Olivier D Christopheet al. Blood, 2019, 134 (19), pp.1632-1644. ⟨10.1182/blood.2019000281⟩ Article dans une revue inserm-03116956v1
The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent Julie Rayes,Soumaya Jadoui,Siân Lax,Angèle Gros,Surasak Wichaiyoet al. Haematologica, 2018, 103 (6), pp.e256-e258. ⟨10.3324/haematol.2017.182162⟩ Article dans une revue (data paper) hal-04456875v1
Advances in Clinical and Basic Science of Coagulation: Illustrated abstracts of the 9th Chapel Hill Symposium on Hemostasis Wolfgang Bergmeier,Silvio Antoniak,Edward Conway,Cécile Denis,Lindsey Georgeet al. Research and Practice in Thrombosis and Haemostasis, 2018, 2 (3), pp.407-428. ⟨10.1002/rth2.12095⟩ Article dans une revue hal-04456872v1
Impact of PI3Kα (Phosphoinositide 3-Kinase Alpha) Inhibition on Hemostasis and Thrombosis Pierre-Alexandre Laurent,Béatrice Hechler,Romain Solinhac,Ashraf Ragab,Cendrine Cabouet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2018, 38 (9), pp.2041-2053. ⟨10.1161/ATVBAHA.118.311410⟩ Article dans une revue hal-04457846v1
Macrophage scavenger receptor SR-AI contributes to the clearance of von Willebrand factor Nikolett Wohner,Vincent Muczynski,Amel Mohamadi,Paulette Legendre,Valérie Proulleet al. Haematologica, 2018, 103 (4), pp.728-737. ⟨10.3324/haematol.2017.175216⟩ Article dans une revue hal-04456818v1
A mutation of the human EPHB2 gene leads to a major platelet functional defect Eliane Berrou,Christelle Soukaseum,Rémi Favier,Frédéric Adam,Ziane Elaibet al. Blood, 2018, 132 (19), pp.2067-2077. ⟨10.1182/blood-2018-04-845644⟩ Article dans une revue hal-04449239v1
A factor VIII–nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation Vincent Muczynski,Caterina Casari,François Moreau,Gabriel Ayme,Charlotte Kaweckiet al. Blood, 2018, 132 (11), pp.1193-1197. ⟨10.1182/blood-2018-01-829523⟩ Article dans une revue hal-03209466v1
Macrophage scavenger receptor SR-AI contributes to the clearance of von Willebrand factor Nikolett Wohner,Vincent Muczynski,Amel Mohamadi,Paulette Legendre,Valérie Proulleet al. Haematologica, 2018, 103 (4), pp.728-737. ⟨10.3324/haematol.2017.175216⟩ Article dans une revue pasteur-03209471v1
VWF clearance: it’s glycomplicated Cécile Denis,Peter J. Lenting Blood, 2018, HITH, 131 (8), pp.842-843. ⟨10.1182/blood-2018-01-824904⟩ Article dans une revue hal-04449623v1
A mutation in the gene coding for the sialic acid transporter SLC35A1 is required for platelet life span but not proplatelet formation Alexandre Kauskot,Tiffany Pascreau,Frédéric Adam,Arnaud Bruneel,Christelle Reperantet al. Haematologica, 2018, 103 (12), pp.e613-e617. ⟨10.3324/haematol.2018.198028⟩ Article dans une revue hal-04455614v1
A factor VIII–nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation Vincent Muczynski,Caterina Casari,François Moreau,Gabriel Aymé,Charlotte Kaweckiet al. Blood, 2018, 132 (11), pp.1193-1197. ⟨10.1182/blood-2018-01-829523⟩ Article dans une revue (data paper) hal-04456589v1
Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets Caterina Casari,David Paul,Sophie Susen,Cécile Lavenu-Bombled,Annie Harrocheet al. Blood Advances, 2018, 2 (12), pp.1417-1428. ⟨10.1182/bloodadvances.2017014290⟩ Article dans une revue hal-04376230v1
Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions Vincent Muczynski,Gabriel Aymé,Véronique Regnault,Marc Vasse,Delphine Borgelet al. Blood, 2017, 129 (17), pp.2443-2454. ⟨10.1182/blood-2016-06-724351⟩ Article dans une revue hal-03567147v1
A Novel Single-Domain Antibody Against von Willebrand Factor A1 Domain Resolves Leukocyte Recruitment and Vascular Leakage During Inflammation—Brief Report Gabriel Ayme,Frédéric Adam,Paulette Legendre,Amine Bazaa,Valérie Proulleet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2017, 37 (9), pp.1736-1740. ⟨10.1161/ATVBAHA.117.309319⟩ Article dans une revue pasteur-03209478v1
Biological outcome and mapping of total factor cascades in response to HIF induction during regenerative angiogenesis Abdel-Majid Khatib,Rachid Lahlil,Martin Hagedorn,Claudine Delomenie,Olivier Christopheet al. Oncotarget, 2016, 7 (11), pp.12102-12120. ⟨10.18632/oncotarget.7728⟩ Article dans une revue hal-03519971v1
Soluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity Marion Pepin,Soraya Mezouar,Julie Pegon,Vincent Muczynski,Frédéric Adamet al. Scientific Reports, 2016, 6 (1), pp.37953. ⟨10.1038/srep37953⟩ Article dans une revue hal-01455400v1
LIM kinase/cofilin dysregulation promotes macrothrombocytopenia in severe von Willebrand disease-type 2B Alexandre Kauskot,Sonia Poirault-Chassac,Frédéric Adam,Vincent Muczynski,Gabriel Aymeet al. JCI Insight, 2016, 1 (16), pp.e88643. ⟨10.1172/jci.insight.88643⟩ Article dans une revue hal-03209475v1
A Laboratory Phenotype/Genotype Correlation of 1167 French Patients From 670 Families With von Willebrand Disease Agnès Veyradier,Pierre Boisseau,Edith Fressinaud,Claudine Caron,Catherine Ternisienet al. Medicine, 2016, 95 (11), pp.e3038. ⟨10.1097/MD.0000000000003038⟩ Article dans une revue hal-01872774v1
von Willebrand factor: at the crossroads of bleeding and thrombosis. Cécile Denis,Peter J. Lenting International Journal of Hematology, 2012, 95 (4), pp.353-61. ⟨10.1007/s12185-012-1041-x⟩ Article dans une revue inserm-00689902v1
Effectiveness of therapeutic communities: a systematic review Marion Malivert,Mélina Fatseas,Cécile Denis,Emmanuel Langlois,Marc Auriacombe European Addiction Research, 2012, 18 (1), pp.1-11. ⟨10.1159/000331007⟩ Article dans une revue halshs-00646645v1
Arterial thrombosis: relevance of a model with two levels of severity assessed by histologic, ultrastructural and functional characterization Beatrice Hechler,Christelle Nonne,Anita Eckly,Stéphanie Magnenat,Jean-Yves Rinckelet al. Journal of Thrombosis and Haemostasis, 2010, 8 (1), pp.173-184. ⟨10.1111/j.1538-7836.2009.03666.x⟩ Article dans une revue hal-04814318v1
Clearance of von Willebrand factor. Cécile V. Denis,Olivier D. Christophe,Beatrijs D. Oortwijn,Peter J. Lenting Thrombosis and Haemostasis, 2008, 99 (2), pp.271-8 Article dans une revue (article de synthèse) inserm-00260376v1
Epilepsy in Dcx knockout mice associated with discrete lamination defects and enhanced excitability in the hippocampus. Marika Nosten-Bertrand,Caroline Kappeler,Céline Dinocourt,Cécile Denis,Johanne Germainet al. PLoS ONE, 2008, 3 (6), pp.e2473. ⟨10.1371/journal.pone.0002473⟩ Article dans une revue inserm-00378410v1
Parallel Loss of Hippocampal LTD and Cognitive Flexibility in a Genetic Model of Hyperdopaminergia. Elise Morice,Jean-Marie Billard,Cécile Denis,Flavie Mathieu,Catalina Betancuret al. Neuropsychopharmacology, 2007, 32 (10), pp.2108-16. ⟨10.1038/sj.npp.1301354⟩ Article dans une revue inserm-00166900v1

Communication dans un congrès (34)

A novel β1-tubulin mutation associated with secretion-dependent platelet hyperactivity and prothrombotic risk via GPVI and CLEC-2 engagement Toscane Viellard,Jean Solarz,Christelle Repérant,Christelle Soukaseum,Johannes A Ebleet al. 7th EUPLAN International Conference, Sep 2025, Wuerzburg, Germany Communication dans un congrès inserm-05293799v1
vWF/GPIb mechano-dependent interactions require F-actin disassembly by the oxidoreductase MICAL1 Jean Solarz,Christelle Soukaseum,Christelle Reperant,Stéphane Frémont,Thibaud Séfianeet al. GTH, 2025, 69th Annual Meeting of the Society of Thrombosis and Haemostasis Research – Advances Research Technology Education, Feb 2025, Lausanne ( CH), Switzerland. pp.S97, ⟨10.1055/s-0044-1801697⟩ Communication dans un congrès hal-05077230v1
Une nouvelle mutation de la tubuline β1 associée à un profil prothrombotique dépendant de l’axe GPVI et de la sécrétion Toscane Viellard,Christelle Repérant,Jean Solarz,Jean-Claude Bordet,Cécile Deniset al. Congrès de la Société Française d'Hématologie, Apr 2025, Paris, France Communication dans un congrès hal-05151565v1
F-actin disassembly by the oxidoreductase MICAL1 promotes mechano-dependent VWF-GPIBa interaction in platelets Jean Solarz,Christelle Soukaseum,Stéphane Frémont,Sébastien Eymieux,Camilia Nabliet al. Société Française de Thrombose et d'hémostase, Oct 2025, Lyon, France Communication dans un congrès hal-05305768v1
Modulation mécanosensible des interactions vWF/GPIb par le désassemblage du cytosquelette d'actine induit par MICAL1 Jean Solarz,Christelle Soukaseum,Stéphane Frémont,Christelle Repérant,Sébastien Eymieuxet al. Société Française d'hématologie, Apr 2025, Paris, France Communication dans un congrès hal-05151554v1
A consistent in vivo factor VIII-equivalence is unlikely to exist for non-factor therapies Hortense Maynadié,Thibaud Sefiane,Genevieve Mccluskey,Marie Clavel,Ivan Peyronet al. Congrès Français d'Hémostase, Société Française de Thrombose et d'Hémostase, Sep 2024, Lille, France Communication dans un congrès hal-04701045v1
L'angiopoïétine-2 se lie à de multiples sites interactifs au sein du facteur von Willebrand Alexis Texier,Peter J. Lenting,Cécile Denis,Stéphanie Roullet,Olivier Christophe 44ème congrès de la Société Française d'Hématologie, Société Française d'Hématologie, Mar 2024, Paris, France. pp.P327, Abstract 18-03 Communication dans un congrès inserm-04541054v1
Fitusiran-treatment modulates the ratio between alpha- and beta-antithrombin isoforms Geneviève Mccluskey,Hortense Maynadié,Caterina Casari,Delphine Borgel,Laurent Frenzelet al. Congrès Français d'Hémostase, Société Française de Thrombose et d'Hémostase, Sep 2024, Lille, France Communication dans un congrès hal-04701035v1
Fitusiran displays efficient pro-hemostatic activity in a mouse model of inducible factor X-deficiency Genevieve Mccluskey,Sebastien Verhenne,Hortense Maynadié,Cécile Denis,Olivier Christopheet al. World Federation of Hemophilia, World Federation of Hemophilia, Apr 2024, Madrid, Spain Communication dans un congrès hal-04654270v1
Mise en évidence dans un modèle murin d’un risque prothrombotique associé à une mutation de la tubuline β1 Toscane Viellard,Christelle Repérant,Jean Solarz,Jean-Claude Bordet,Cécile Deniset al. Congrès Français d'Hémostase, Société Française de Thrombose et d'Hémostase, Sep 2024, Lille, France Communication dans un congrès hal-04701038v1
L'angiopoïétine-2 se lie à de multiples sites interactifs au sein du facteur von Willebrand Alexis Texier,Peter J. Lenting,Cécile Denis,Stéphanie Roullet,Olivier Christophe 44e congrès annuel de la Société Française d’Hématologie, Société Française d’Hématologie, Mar 2024, Paris, France. p 327, abstract 18-03 Communication dans un congrès hal-04654288v1
Mise en évidence dans un modèle murin d’un risque prothrombotique associé à une mutation de la tubuline β1 Toscane Viellard,Christelle Repérant,Jean Solarz,Jean-Claude Bordet,Cécile Deniset al. Congrès Français d'Hémostase (CFH) 2024, Sep 2024, Lille, France Communication dans un congrès hal-05151543v1
Une nouvelle mutation de la tubuline β1 associée à un profil prothrombotique dépendant de l’axe GPVI et de la sécrétion Toscane Viellard,Christelle Repérant,Jean Solarz,Jean-Claude Bordet,Cécile Deniset al. Club Français des Plaquettes et des Mégacaryocytes (CFPM), Oct 2024, Saint Etienne, France Communication dans un congrès hal-05151561v1
Allele-selective inhibition of mutant von Willebrand factor with small interfering RNAs to ameliorate a von Willebrand disease type 2B phenotype in vivo in mice Linthorst Noa,Jongejan Yvonne,Bierings Ruben,Dahlman Je,Cécile Deniset al. Congress of the International Society on Thrombosis and Haemostasis, International Society on Thrombosis and Haemostasis, Jun 2023, Montreal (Canada), Canada. pp.100553. Abstract OC 08.5 Communication dans un congrès hal-04501151v1
A single-domain antibody enhancing protein S activity reduces vaso-occlusion in two murine models of sickle cell disease Claire Auditeau,Thiago Maciel,Josepha Sedzro,Camille Roussel,Aurélie Fricot-Monsinjonet al. European Congress on Thrombosis and Haemostasis, Sep 2023, Valence (Espagne), Spain Communication dans un congrès hal-04501174v1
MICAL1, un nouvel acteur moléculaire impliqué dans la stabilisation du thrombus Jean Solarz,Christelle Soukaseum,Cécile Denis,Frédéric Adam,Alexandre Kauskot Congrès Société Française d’Hématologie 2023, Mar 2023, Paris, France Communication dans un congrès hal-04455383v1
Llama-derived single-domain antibodies blocking tissue factor pathway inhibitor and increasing thrombin generation in FVIII- and FX-deficient plasma Francois Saller,Ivan Peyron,Andrea Ruty,Saenjamsai P,Claire Auditeauet al. European Congress on Thrombosis and Haemostasis, Sep 2023, Valence (Espagne), Spain Communication dans un congrès hal-04501177v1
MICAL1, un nouvel acteur des forces contractiles dans le thrombus Jean Solarz,Christelle Soukaseum,Frédéric Adam,Cécile Denis,Alexandre Kauskot Club Français de Plaquettes et des Mégacaryocytes, May 2022, Bordeaux, France Communication dans un congrès hal-04455372v1
Effects of platelet-inspired haemostatic nanoparticles on bleeding in von Willebrand disease murine models Stéphanie Roullet,Norman Luc,Julie Rayes,Frédéric Adam,Andrew J Ditoet al. ISTH 2022 Congress, International Society of Thrombosis and Hemostasis, 2022, Londres, United Kingdom Communication dans un congrès hal-04455066v1
Transplacental Delivery of Maternal FVIII for Induction of FVIII-specific Immune Tolerance Angelina Mimoun,Melissa Bou Jaoudeh,Ivan Peyron,Victoria Daventure,Sandrine Delignatet al. Hybrid Congress of the International Society on Thrombosis and Haemostasis, International Society on Thrombosis and Haemostasis, Jul 2021, Philadelphia (Pennsylvania), United States. pp.Abstract OC 14.1 Communication dans un congrès hal-04501088v1
Antithrombotic Potential of a Single-domain Antibody Enhancing the Anticoagulant Activity of Protein S Josepha Sedzro,Frédéric Adam,Allan De Carvalho,Elsa P Bianchini,Ivan Peyronet al. Hybrid Congress of the International Society on Thrombosis and Haemostasis, International Society on Thrombosis and Haemostasis, Jul 2021, Philadelphia (Pennsylvania), United States. pp.Abstract OC 60.2 Communication dans un congrès hal-04501112v1
Caractérisation d’une nanobody qui potentialize l’activité cofacteur de la protéine C active de la protéine S Sedzro Jc,Francois Saller,Frédéric Adam,De Carvalho,Sophie Gandrilleet al. 40ème congrès de la Société Française d’Hématologie, Société Française d’Hématologie, Sep 2020, Paris, France. pp.Page 39, Abstract 04-01 Communication dans un congrès hal-04501074v1
p.(Pro2145Thrfs*5) et p.(Cys2216Phefs*9), deux Nouvelles mutations identifiées dans le domaine D4 du facteur von Willebrand chez des patientes d’origine afro-caribéenne Marie Daniela Dubois,Serge Pierre-Louis,Johalène Rabout,Cécile Denis,Olivier Christopheet al. 40ème congrès de la Société Française d’Hématologie, Société Française d’Hématologie, Sep 2020, Paris, France. p 50, Abstract 05-07 Communication dans un congrès hal-04501081v1
L'ADP sécrétée par la voie de signalisation calcique plaquettaire NAADP/SERCA3 active spécifiquement le récepteur purinergique P2Y12 et pas P2Y1 Miao Feng,Cécile Denis,Regis Bobe,Jean‐philippe Rosa 8ème rencontre Club français des plaquettes et des mégacayocytes, Nov 2020, plateforme zoom, France Communication dans un congrès hal-04455261v1
A inducible mouse model of Factor X deficiency to test novel FX therapeutics Sebastien Verhenne,Loubiere C,Cécile Denis,Peter J. Lenting,Olivier Christophe XXVIIth Congress of the International Society on Thrombosis and Haemostasis, International Society on Thrombosis and Haemostasis, Jul 2019, Melbourne (AUS), Australia. pp.Abstract OC 28.4 Communication dans un congrès hal-04499851v1
La rupture de l'interaction entre la filamine A et le complexe aIIbb3 conduit à l'activation de la voie RhoA entraînant une macrothrombocytopénie Alessandro Donada,Balayn N,Sliwa D,Larissa L,Ceglia Vet al. 39th Congress of the Société Française d’Hématologie, Société Française d’Hématologie, Mar 2019, Paris, France. pp.142 Communication dans un congrès hal-04498415v1
Von Willebrand factor induces human vascular smooth muscle cells proliferation through low density lipoprotein-related receptor 4 and alphavbeta3 integrin Morel Worou,Melusine Didelot,Vincent Muczynski,Raoul A,Paulette Legendreet al. XXVIIth Congress of the International Society on Thrombosis and Haemostasis, International Society on Thrombosis and Haemostasis, Jul 2019, Melbourne (AUS), Australia Communication dans un congrès hal-04498513v1
Diagnostic moléculaire de la maladie de von Willebrand de type 1C avec trouble de la clairance et mutation de la région propeptide Dubois Md,Pierre-Louis S,Bourdin C,Cécile Denis,Johalène Raboutet al. 39th Congress of the Société Française d’Hématologie, Société Française d’Hématologie, Mar 2019, Paris, France. pp.142 Communication dans un congrès hal-04498426v1
Développement d’un modèle de souris avec un déficit inductible en facteur X Sebastien Verhenne,Loubière Cécile,Elena Barbon,F Mingozzi,Cécile Deniset al. 39th Congress of the Société Française d’Hématologie, Société Française d’Hématologie, Mar 2019, Paris, France. pp.Abstract 12-29 Communication dans un congrès hal-04498403v1
Targeting Protease Nexin-1, a natural anticoagulant to control bleeding in hemophilia A Karen Aymonnier,Charlotte Kawecki,Laurence Venisse,Emmanuelle de Raucourt,Olivier Christopheet al. XXVIIth Congress of the International Society on Thrombosis and Haemostasis, International Society on Thrombosis and Haemostasis, Jul 2019, Melbourne (AUS), Australia. pp.Abstract OC 75.3 Communication dans un congrès hal-04498448v1
The potential use of nanobodies delivered via AAV vectors in the treatment of hemophilia Elena Barbon,Gabriel Ayme,Amel Mohamadi,Cécile Denis,Olivier Christopheet al. 21st Annual Meeting of the American Society of Gene and Cell Therapy, American Society of Gene and Cell Therapy, May 2018, CHICAGO, United States Communication dans un congrès hal-04457494v1
La Protéase Nexine-1, un inhibiteur physiologique de la thrombine, cible potentielle dans le traitement de l’hémophilie. Karen Aymonnier,Charlotte Kawecki,Laurence Venisse,Emmanuelle de Raucourt,Olivier Christopheet al. 38th Congress of the Société Française d’Hématologie, Société Française d’Hématologie, Mar 2018, PARIS, France. p 133, Abstract 12-59 Communication dans un congrès hal-04457483v1
Targeting Protease Nexin-1, a natural anticoagulant to control bleeding in hemophilia A Karen Aymonnier,Charlotte Kawecki,Laurence Venisse,Emmanuelle de Raucourt,Olivier Christopheet al. 2nd European Congress on Thrombosis and Haemostasis, Oct 2018, Marseille, France Communication dans un congrès hal-04457505v1
Maladie de Willebrande type 2B et thrombopénies : Impact de la désialylation des plaquettes. Annabelle Dupont,Christelle Soukaseum,Frédéric Adam,Paulette Legendre,Valérie Proulleet al. 38th Congress of the Société Française d’Hématologie, Société Française d’Hématologie, Mar 2018, Paris, France. pp.Page 143, Abstract 12-88 Communication dans un congrès hal-04457466v1

Poster de conférence (19)

A novel β1-tubulin mutation associated with a secretion-dependent platelet hyperactivity and prothrombotic risk Toscane Viellard,Jean Solarz,Christelle Repérant,Christelle Soukaseum,Cécile Deniset al. ECTH 2025 Prague, Oct 2025, Prague (CZ), Czech Republic Poster de conférence hal-05351155v1
Contrôle mécanosensible de la dynamique de l’actine dans la fonctionnalité de la GPIbα par MICAL1 Jean Solarz,Christelle Soukaseum,Christelle Repérant,Cécile Denis,Dominique Baruchet al. Congrès Français d'Hémostase, Sep 2024, Lille, France Poster de conférence hal-04701025v1
Le récepteur PAR4 initie la voie SERCA3/NAADP qui potentialise l'activation des plaquettes en réponse à la thrombine. Miao Feng,Frédéric Adam,Alexandre Kauskot,Cécile Denis,Marijke Bryckaertet al. Congrès Francais d'Hémostase, May 2023, Saint malo, France Poster de conférence hal-04455436v1
Effect of allele-selective silencing of von Willebrand factor in mice on experimental bleeding and thrombosis models Jongejan Yvonne,Linthorst Noa,Schrader E,Laan Snj,R.J. Dirvenet al. Congress of the International Society on Thrombosis and Haemostasis, Jun 2023, Montreal, Canada. Res. Pract. Thromb. Haemost., 7 (Suppl. 2), pp.Abstract PB 1431, 2023 Poster de conférence hal-04501158v1
MICAL1 links actin dynamics to shear-dependent adhesive and thrombotic function of platelets Jean Solarz,Christelle Soukaseum,Christelle Repérant,Cécile Denis,Frédéric Adamet al. Congrès Français d’Hémostase, May 2023, Saint-Malo, France Poster de conférence hal-04455404v1
MICAL1, a new molecular actor involved in thrombus growth and stability Jean Solarz,Christelle Soukaseum,Christelle Repérant,Stéphane Frémont,Cécile Deniset al. Gordon Research Conference, Cell Biology of Megakaryocytes and Platelets, Mar 2023, Lucca (Barga), Italy Poster de conférence hal-05151535v1
MAGT1 DEFICIENCY CAUSES A PROMINENT PLATELETS DYSFUNCTION THROUGH IMPAIRMENT OF MEMBRANE GLYCOPROTEINS N-GLYCOSYLATION Alexandre Kauskot,Coralie Mallebranche,Jean Solarz,Miao Feng,Toscane Viellardet al. 20th Biennial Meeting of the European Society for Immunodeficiencies (ESID), Oct 2022, Gothenburg, Sweden. Abstract 801 Poster de conférence hal-04455514v1
Resistance to Fibrinolysis in Critically Ill Patients with COVID-19 Can Be Overcome by N-acetylcysteine in vitro Dorothée Faille,Marie Charlotte Bourrienne,Gay J,Benoit Ho Tin Noé,Stephane Loyauet al. Hybrid Congress of the International Society on Thrombosis and Haemostasis, Jul 2021, Philadelphia (Pennsylvania), United States. Res. Pract. Thromb. Haemost, 5 (Suppl. 1), pp.Abstract LPB0104, 2021 Poster de conférence hal-04501103v1
Von Willebrand Factor Induces Vascular Smooth Muscle Cell Proliferation And Migration Through Low Density Lipoprotein-Related Receptor Protein 4 And αvβ3 Integrin Jeremy Lagrange,Jean-Baptiste Michel,Alexandre Raoul,Peter J. Lenting,Patrick Lacolleyet al. American Heart Association's Vascular Discovery: From Genes to Medicine 2020 Scientific Sessions, May 2020, Virtual meeting (Live and on-demand), France. Arteriosclerosis, Thrombosis, and Vascular Biology, 40 (Suppl1), pp.Abstract 304, 2020 Poster de conférence hal-04499901v1
Transplacental delivery of maternal factor VIII for induction of immune tolerance to therapeutic factor VIII Angelina Mimoun,Melissa Bou Jaoudeh,Ivan Peyron,Daventure V,Sandrine Delignatet al. Virtual Congress of the International Society on Thrombosis and Haemostasis, Jul 2020, Milan (Virtual), Italy. Res. Pract. Thromb. Haemost, 4 (Suppl. 1), pp.Abstract PB0177, 2020 Poster de conférence hal-04501045v1
NAADP/SERCA3-dependent Ca2+ stores pathway specifically controls early autocrine ADP secretion potentiating platelet activation. Miao Feng,Ziane Elaib,Delphine Borgel,Cécile V. Denis,Frédéric Adamet al. ISTH 2020, Jul 2020, Virtual congress, France Poster de conférence hal-04455286v1
Standardization of a Flow Cytometry Platelet Sialylation Assay, and reference Values forBeta-Galactose Exposure in Healthy Subjects Dominique Lasne,Tiffany Pascreau,Sadyo Darame,Marie-Charlotte Bourrienne,Aurélien Philippeet al. ISTH, 2020, Jul 2020, Milan (Italie), Italy. PB0441 Poster de conférence hal-04454870v1
Prothrombotic gain-of-functin variants of von Willebrand factor. V. Huck,Alexander Tischer,Mess C,Tobias Obser,Köning Get al. Virtual Congress of the International Society on Thrombosis and Haemostasis, Jul 2020, Milan (Virtual), Italy. Res. Pract. Thromb. Haemost, 4 (Suppl. 1), pp.Abstract PB1584, 2020 Poster de conférence hal-04501054v1
NAADP/SERCA3-Dependent Ca2+ Stores Pathway Specifically Controls Early Autocrine ADP Secretion Potentiating Platelet Activation Miao Feng,Ziane Elaib,Delphine Borgel,Cécile Denis,Frederic Adamet al. Virtual Congress of the International Society on Thrombosis and Haemostasis, Jul 2020, Milan (Virtual), Italy. Res. Pract. Thromb. Haemost, 4 (Suppl. 1), pp.Abstract PB1745, 2020 Poster de conférence hal-04501065v1
Phosphoinositide 3-kinase  (PI3K) triggers PI3K activation at low levels of GPVI stimulation and controls platelet arrest on von Willebrand factor ar arterial shear. Laurent P-A,Beatrice Hechler,Solinhac R,Cabou C,Anquetil Tet al. XXVIIth Congress of the International Society on Thrombosis and Haemostasis, Jul 2019, Melbourne (AUS), Australia. Res. Pract. Thromb. Haemost, 3 (Suppl. 1), pp.Abstract PB463, 2019 Poster de conférence hal-04499868v1
Development of single domain antibodies targeting protease nexin-1 as a strategy for hemophilia treatment Charlotte Kawecki,Karen Aymonnier,Laurence Venisse,Véronique Arocas,Olivier Christopheet al. XXVIIth Congress of the International Society on Thrombosis and Haemostasis, Jul 2019, Melbourne (AUS), Australia. Res. Pract. Thromb. Haemost, 3 (Suppl. 1), pp.Abstract PB0316, 2019 Poster de conférence hal-04499858v1
The VWF-GPIb interaction mediates thrombo-inflammation in experimental stroke via recruitment of monocytes, neutrophils and T-cells to the brain Frederik Denorme,Kimberly Martinod,Vandebulcke A,Cécile Denis,Peter J. Lentinget al. XXVIIth Congress of the International Society on Thrombosis and Haemostasis, Jul 2019, Melbourne (AUS), Australia. Res. Pract. Thromb. Haemost., 3 (Suppl. 1), pp.Abstract PB1002, 2019 Poster de conférence hal-04499886v1
Relevance of platelet desialylation and thrombocytopenia in type 2B von Willebrand disease Annabelle Dupont,Christelle Soukaseum,Mathilde Cheptou,Frédéric Adam,Thomas Nipotiet al. GRC, Cell biology of megakaryocytes and platelets, 2019, Mar 2019, Galveston - Texas, United States Poster de conférence hal-04455289v1
Modulation of the platelet count by Romiplostim and inhibitors of LIM kinase in genetically-engineered von Willebrand disease type 2B mice: in vivo evaluation of haemostatic efficiency. Mathilde Cheptou,Frédéric Adam,Olivier Christophe,Peter Lenting,Cécile Deniset al. ECTH, 2018, Oct 2018, Marseille, France Poster de conférence hal-04455308v1

Proceedings/Recueil des communications (3)

Thrombin-mediated cleavage of membrane endoglin: Implications in endothelial dysfunction Divina El Hamaoui,Aurore Marchelli,Sophie Gandrille,Alain Stepanian,Franck Lebrinet al. 17th Annual Congress of the European Association for Haemophilia and Allied Disorders 2024, Haemophilia, 30 (S1), pp.34-188, 2024, ⟨10.1111/hae.14919⟩ Proceedings/Recueil des communications hal-04460082v1
Design and Characterization of FLT210, a Potent Next Generation AAV-hFVIII Vector Candidate Azadeh Kia,Fabrizio Comper,Samantha Correia,Caterina Casari,Segen Negashet al. 61 ASH Annual Meeting, Blood, 134 (Supplement_1), pp.4638-4638, 2019, ⟨10.1182/blood-2019-128490⟩ Proceedings/Recueil des communications hal-04461585v1
Thrombin-mediated activation of factor VIII is insufficient to produce all necessary cofactor activity in vivo Charlotte Kawecki,Ivan Peyron,Amine Bazaa,Vincent Muczynski,Stephen Ferrièreet al. Congress of the International Society of Thrombosis and Haemostasis, Research and Practice in Thrombosis and Haemostasis, 3, pp.1-891, 2019, ⟨10.1002/rth2.12229⟩ Proceedings/Recueil des communications hal-04461945v1