Cedric Le May DR2 CNRS

Identifiants chercheurs

IdHAL :

cedric-le-may

ORCID :

0000-0002-7554-792X

IdRef :

089049853

Publications

Article dans une revue (87)

Versatile Functions of Hepatic Lipase in Lipoprotein Metabolism Wieneke Dijk,Antoine Rimbert,Thibaud Sotin,Cedric Le May,Bertrand Cariou Arteriosclerosis, Thrombosis, and Vascular Biology, 2026, 46 (1), pp.105-118. ⟨10.1161/ATVBAHA.125.323051⟩ Article dans une revue hal-05500165v1
Polymorphic Size of Lipoprotein(a) and Structural Bioprosthetic Valve Degeneration Romain Capoulade,Mikaël Croyal,Thomas Sénage,Guillaume Guimbretière,Cedric Le Mayet al. JACC: Cardiovascular Imaging, 2025, 18 (10), pp.1167 - 1169. ⟨10.1016/j.jcmg.2025.05.007⟩ Article dans une revue hal-05392595v1
Effect of alirocumab on postprandial hyperlipidaemia in patients with type 2 diabetes: A randomized, double‐blind, placebo‐controlled, cross‐over trial Bertrand Cariou,An Thys,Arsênio Rodrigues Oliveira,Marine P.M. Letertre,Béatrice Guyomarchet al. Diabetes, Obesity and Metabolism, 2025, ⟨10.1111/dom.16305⟩ Article dans une revue hal-04992510v1
Lp(a) concentration and polymorphic size are not associated with new onset diabetes in individuals with prediabetes Maxime Carpentier,Matthieu Wargny,Mikaël Croyal,Cedric Le May,Sarra Smatiet al. Diabetes & Metabolism, 2025, 51 (2), pp.101621. ⟨10.1016/j.diabet.2025.101621⟩ Article dans une revue hal-05387580v1
Methylglyoxal-Induced Glycation of Plasma Albumin: From Biomarker Discovery to Clinical Use for Prediction of New-Onset Diabetes in Individuals with Prediabetes Arsênio Rodrigues Oliveira,Chloé Chevalier,Matthieu Wargny,Victoria Pakulska,Cédric Caradeucet al. Clinical Chemistry, 2025, 71 (6), pp.688-699. ⟨10.1093/clinchem/hvaf035⟩ Article dans une revue hal-05387570v1
Efficacy of Semaglutide as Adjuvant Treatment for Sleeve Gastrectomy: A Proof‐of‐Concept Study in Mice Samuel Frey,Clément Louis-Gaubert,Amélie Thouzeau,Lola Cossé,Victoria Lorantet al. Obesity, 2025, 33 (11), pp.2061-2066. ⟨10.1002/oby.70003⟩ Article dans une revue hal-05387547v1
A rare gain of function variant of hepatic lipase attenuates hypercholesterolemia and atherosclerosis in mice via an LDL receptor-independent mechanism Thibaud Sotin,Xiaoke Ge,Milena Schönke,Lucie Vince,Amélie Thouzeauet al. Cardiovascular Research, 2025, 121 (7), pp.1024-1035. ⟨10.1093/cvr/cvaf097⟩ Article dans une revue inserm-05193295v1
From Genetic Findings to new Intestinal Molecular Targets in Lipid Metabolism Cedric Le May,Simon Ducheix,Bertrand Cariou,Antoine Rimbert Current Atherosclerosis Reports, 2025, 27 (1), pp.26. ⟨10.1007/s11883-024-01264-w⟩ Article dans une revue hal-05361443v1
Post-translational modifications of apolipoproteins as promising biomarkers for diabetes-related cardiovascular diseases: A comprehensive review Chloé Chevalier,Arsênio Rodrigues Oliveira,Valentin Blanchard,Cedric Le May,Bertrand Cariouet al. Diabetes & Metabolism, 2025, 51 (5), pp.101683. ⟨10.1016/j.diabet.2025.101683⟩ Article dans une revue hal-05387543v1
Gestational cholestyramine treatment protects adult offspring of ApoE ‐deficient mice against maternal‐hypercholesterolemia‐induced atherosclerosis Marina Habib,Mikael Croyal,Bertrand Kaeffer,Isabelle I. Grit,Blandine Castellanoet al. Acta Physiologica, 2024, 240 (5), pp.e14133. ⟨10.1111/apha.14133⟩ Article dans une revue hal-04797680v1
Primary hypocholesterolemia is associated with an increased risk of hepatic complications in the general population Matthieu Wargny,Thomas Goronflot,Antoine Rimbert,Jérôme Boursier,Sofiane Kabet al. Journal of Hepatology, 2024, 80 (6), pp.846-857. ⟨10.1016/j.jhep.2024.01.030⟩ Article dans une revue hal-04474613v2
Human induced pluripotent stem cells ‐derived liver organoids grown on a Biomimesys® hyaluronic acid‐based hydroscaffold as a new model for studying human lipoprotein metabolism Meryl Roudaut,Amandine Caillaud,Zied Souguir,Lise Bray,Aurore Girardeauet al. Bioengineering & Translational Medicine, 2024, ⟨10.1002/btm2.10659⟩ Article dans une revue (data paper) hal-04509118v1
Empagliflozin mitigates metabolic dysfunction‐associated steatotic liver disease by reducing de novo lipogenesis in a mouse model of lipoatrophic diabetes Sarra Smati,Thibaud Sotin,Perrine Deniel,Simon Ducheix,Michael Joubertet al. Diabetes, Obesity and Metabolism, 2024, 26 (8), pp.3466-3470. ⟨10.1111/dom.15634⟩ Article dans une revue hal-04797985v1
PCSK9 inhibition protects mice from food allergy Victoria Lorant,Martin Klein,Damien Garçon,Thibaud Sotin,Samuel Freyet al. Translational Research, The Journal of Laboratory and Clinical Medicine, 2024, 272, pp.151-161. ⟨10.1016/j.trsl.2024.03.001⟩ Article dans une revue hal-04529957v1
LDL lowering effect of PCSK9 inhibition is reduced in women Veronika Myasoedova,Antoine Rimbert,Marina Camera,Cedric Le May,Romain Capouladeet al. European Heart Journal - Cardiovascular Pharmacotherapy, 2023, 9 (4), pp.337-342. ⟨10.1093/ehjcvp/pvad009⟩ Article dans une revue hal-04212334v1
Generation of an induced pluripotent stem cell line (ITXi012-A) from a patient with genetically determined high-lipoprotein(a) plasma levels Amandine Caillaud,Lise Bray,Aurore Girardeau,Zoé Begué-Racapé,Lucie Vinceet al. Stem Cell Research, 2023, 72, ⟨10.1016/j.scr.2023.103205⟩ Article dans une revue hal-04212298v1
Nutritional biomarkers and heart failure requiring hospitalization in patients with type 2 diabetes: the SURDIAGENE cohort Matthieu Wargny,Mikaël Croyal,Stéphanie Ragot,Elise Gand,David Jacobiet al. Cardiovascular Diabetology, 2022, 21 (1), pp.101. ⟨10.1186/s12933-022-01505-9⟩ Article dans une revue hal-03869068v1
Identification of a Gain-of-Function LIPC Variant as a Novel Cause of Familial Combined Hypocholesterolemia Wieneke Dijk,Mathilde Di-Filippo Charcosset,Sander Kooijman,Robin Van Eenige,Antoine Rimbertet al. Circulation, 2022, 146 (10), pp.724-739. ⟨10.1161/circulationaha.121.057978⟩ Article dans une revue inserm-03831077v1
Generation of a GPR146 knockout human induced pluripotent stem cell line (ITXi001-A-1) Lise Bray,Amandine Caillaud,Aurore Girardeau,Murielle Patitucci,Cédric Le Mayet al. Stem Cell Research, 2022, 60, pp.102721. ⟨10.1016/j.scr.2022.102721⟩ Article dans une revue hal-03869113v1
PCSK9 deficiency results in a specific shedding of excess LDLR in female mice only: Role of hepatic cholesterol Anna Roubtsova,Damien Garçon,Sandrine Lacoste,Ann Chamberland,Jadwiga Marcinkiewiczet al. Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2022, 1867 (12), pp.159217. ⟨10.1016/j.bbalip.2022.159217⟩ Article dans une revue hal-03869056v1
Effect of Parathyroidectomy on Metabolic Homeostasis in Primary Hyperparathyroidism Samuel Frey,Raphaël Bourgade,Cedric Le May,Mikaël Croyal,Edith Bigot-Corbelet al. Journal of Clinical Medicine, 2022, 11, ⟨10.3390/jcm11051373⟩ Article dans une revue hal-03869109v1
Plasma apolipoprotein concentrations and incident diabetes in subjects with prediabetes Mikaël Croyal,Matthieu Wargny,Kevin Chemello,Chloé Chevalier,Valentin Blanchardet al. Cardiovascular Diabetology, 2022, 21 (1), pp.21. ⟨10.1186/s12933-022-01452-5⟩ Article dans une revue hal-03869138v1
Transintestinal cholesterol excretion in health and disease Damien Garçon,Jean-Matthieu Berger,Bertrand Cariou,Cedric Le May Current Atherosclerosis Reports, 2022, 24 (3), pp.153-160. ⟨10.1007/s11883-022-00995-y⟩ Article dans une revue hal-03869126v1
Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes Yoann Combot,Veijo T. Salo,Gilliane Chadeuf,Maarit Hölttä,Katharina Venet al. Cell Reports, 2022, 38 (2), pp.110213. ⟨10.1016/j.celrep.2021.110213⟩ Article dans une revue hal-03534214v1
Taste-Driven Responsiveness to Fat and Sweet Stimuli in Mouse Models of Bariatric Surgery Aurélie Dastugue,Cedric Le May,Séverine Ledoux,Cindy Le Bourgot,Pascaline Delabyet al. Biomedicines, 2022, Special Issue Animal Models of Human Pathology: Revision, Relevance and Refinements, 10 (4), pp.741. ⟨10.3390/biomedicines10040741⟩ Article dans une revue hal-03869074v1
Orosensory perception of fat/sweet stimuli and appetite-regulating peptides before and after sleeve gastrectomy or gastric by-pass in adult women with obesity Arnaud Bernard,Johanne Le Beyec-Le Bihan,Loredana Radoi,Muriel Coupaye,Ouidad Samiet al. Nutrients, 2021, 13 (3), pp.878. ⟨10.3390/nu13030878⟩ Article dans une revue hal-03170655v1
The Complex ABCG5/ABCG8 Regulates Vitamin D Absorption Rate and Contributes to its Efflux from the Intestine Tiffany Antoine,Cedric Le May,Marielle Margier,Charlotte Halimi,Marion Nowickiet al. Molecular Nutrition and Food Research, 2021, 65 (21), pp.2100617. ⟨10.1002/mnfr.202100617⟩ Article dans une revue hal-03451191v1
The Tryptophan/Kynurenine Pathway: A Novel Cross-Talk between Nutritional Obesity, Bariatric Surgery and Taste of Fat Arnaud Bernard,Cedric Le May,Aurélie Dastugue,Audrey Ayer,Claire Blanchardet al. Nutrients, 2021, 13 (4), pp.1366. ⟨10.3390/nu13041366⟩ Article dans une revue hal-03328777v1
Genetic Inhibition of PCSK9 and Liver Function Antoine Rimbert,Sarra Smati,Wieneke Dijk,Cedric Le May,Bertrand Cariou JAMA Cardiology, 2021, ⟨10.1001/jamacardio.2020.5341⟩ Article dans une revue hal-03100949v1
Effects of proprotein convertase subtilisin kexin type 9 modulation in human pancreatic beta cells function Stéphane Ramin-Mangata,Aurélie Thédrez,Brice Nativel,Nicolas Diotel,Valentin Blanchardet al. Atherosclerosis, 2021, 326, pp.47-55. ⟨10.1016/j.atherosclerosis.2021.03.044⟩ Article dans une revue hal-03353494v1
PCSK9 is not secreted from mature differentiated intestinal cells François Moreau,Aurélie Thédrez,Damien Garçon,Audrey Ayer,Thibaud Sotinet al. Journal of Lipid Research, 2021, 62, pp.100096. ⟨10.1016/j.jlr.2021.100096⟩ Article dans une revue hal-03350100v1
PCSK9 regulates the NODAL signaling pathway and cellular proliferation in hiPSCs Meryl Roudaut,Salam Idriss,Amandine Caillaud,Aurore Girardeau,Antoine Rimbertet al. Stem Cell Reports, 2021, ⟨10.1016/j.stemcr.2021.10.004⟩ Article dans une revue hal-03451184v1
Routine use of statins and increased COVID-19 related mortality in inpatients with type 2 diabetes: Results from the CORONADO study Bertrand Cariou,Thomas Goronflot,Antoine Rimbert,Sandrine Boullu,Cedric Le Mayet al. Journal of Diabetes & Metabolism, 2021, 47 (2), pp.101202. ⟨10.1016/j.diabet.2020.10.001⟩ Article dans une revue hal-03100948v1
P-glycoprotein (ABCB1) is involved in vitamin K efflux Marielle Margier,Cedric Le May,Tiffany Antoine,Charlotte Halimi,Marion Nowickiet al. Food Chemistry, 2021, 343, pp.1-5. ⟨10.1016/j.foodchem.2020.128510⟩ Article dans une revue hal-03012693v1
VLDL (Very-Low-Density Lipoprotein)-Apo E (Apolipoprotein E) May Influence Lp(a) (Lipoprotein [a]) Synthesis or Assembly Mikaël Croyal,Valentin Blanchard,Khadija Ouguerram,Maud Chétiveaux,Léa Cabiochet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, 40 (3), pp.819-829. ⟨10.1161/ATVBAHA.119.313877⟩ Article dans une revue hal-03098122v1
Circulating PCSK9 levels are not associated with the conversion to type 2 diabetes Stéphane Ramin-Mangata,Matthieu Wargny,Matthieu Pichelin,Cedric Le May,Aurélie Thédrezet al. Atherosclerosis, 2020, 293, pp.49-56. ⟨10.1016/j.atherosclerosis.2019.11.027⟩ Article dans une revue hal-03013257v1
Circulating Rather Than Intestinal PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Regulates Postprandial Lipemia in Mice Damien Garçon,François Moreau,Audrey Ayer,Wieneke Dijk,Xavier Prieuret al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, 40 (9), pp.2084-2094. ⟨10.1161/ATVBAHA.120.314194⟩ Article dans une revue hal-03012708v1
A high-throughput mass spectrometry-based assay for large-scale profiling of circulating human apolipoproteins Valentin Blanchard,Damien Garçon,Catherine Jaunet,Kevin Chemello,Stéphanie Billon-Crossouardet al. Journal of Lipid Research, 2020, 61 (7), pp.1128-1139. ⟨10.1194/jlr.D120000835⟩ Article dans une revue hal-03098131v1
Bile acids associate with glucose metabolism, but do not predict conversion from impaired fasting glucose to diabetes Oscar Chávez-Talavera,Matthieu Wargny,Matthieu Pichelin,Amandine Descat,Emmanuelle Vallezet al. Metabolism, 2020, 103, pp.154042. ⟨10.1016/j.metabol.2019.154042⟩ Article dans une revue inserm-02869470v1
Roux-en-Y gastric bypass, but not sleeve gastrectomy, decreases plasma PCSK9 levels in morbidly obese patients C. Blanchard,S. Ledoux,A. Verhaegen,Matthieu Wargny,E. Letessieret al. Journal of Diabetes & Metabolism, 2020, 46 (6), pp.480-487. ⟨10.1016/j.diabet.2020.01.003⟩ Article dans une revue hal-03013255v1
In vivo evidence for transintestinal cholesterol efflux in patients with complete common bile duct obstruction François Moreau,Claire Blanchard,Christophe Perret,Laurent Flet,Frédéric Douaneet al. Journal of clinical lipidology, 2019, 13 (1), pp.213-217.e1. ⟨10.1016/j.jacl.2018.09.010⟩ Article dans une revue hal-02429506v1
Beyond LDL: What Role for PCSK9 in Triglyceride-Rich Lipoprotein Metabolism? Wieneke Dijk,Cedric Le May,Bertrand Cariou Trends in endocrinology and metabolism: TEM, 2018, Equipe IV, 29 (6), pp.420 - 434. ⟨10.1016/j.tem.2018.03.013⟩ Article dans une revue istex hal-01833913v1
Roux-en-Y gastric bypass reduces plasma cholesterol in diet-induced obese mice by affecting trans-intestinal cholesterol excretion and intestinal cholesterol absorption Claire Blanchard,François Moreau,Audrey Ayer,L. Toque,Damien Garçonet al. International Journal of Obesity, 2018, Equipe IV, 42 (3), pp.552--560. ⟨10.1038/ijo.2017.232⟩ Article dans une revue hal-01833321v1
PCSK9 Concentrations in Cerebrospinal Fluid Are Not Specifically Increased in Alzheimer's Disease Hélène Courtemanche,Edith Bigot,Matthieu Pichelin,Béatrice Guyomarch,Claire Boutoleau-Bretonnièreet al. Journal of Alzheimer's Disease, 2018, Equipe IV, ⟨10.3233/JAD-170993⟩ Article dans une revue hal-01833920v1
Unexpected metabolic disorders induced by endocrine disruptors in Xenopus tropicalis provide new lead for understanding amphibian decline Christophe Regnault,Marie Usal,Sylvie Veyrenc,Karine Couturier,Cécile Batandieret al. Proceedings of the National Academy of Sciences of the United States of America, 2018, Equipe IV Therassay, 115 (19), pp.E4416-E4425. ⟨10.1073/pnas.1721267115⟩ Article dans une revue hal-01833911v1
Plasma PCSK9 concentrations during the course of nondiabetic chronic kidney disease: Relationship with glomerular filtration rate and lipid metabolism Marion Morena,Cedric Le May,Leila Chenine,Lucie Arnaud,Anne-Marie Dupuyet al. Journal of clinical lipidology, 2017, 11 (1), pp.87-93. ⟨10.1016/j.jacl.2016.10.005⟩ Article dans une revue hal-01763117v1
The Role of Estrogens in Pancreatic Islet Physiopathology Franck Mauvais-Jarvis,Cedric Le May,Joseph P. Tiano,Suhuan Liu,Gamze Kilic-Berkmenet al. Advances in Experimental Medicine and Biology, 2017, Equipe IV, 1043, pp.385--399. ⟨10.1007/978-3-319-70178-3_18⟩ Article dans une revue hal-01833109v1
Impact of protease inhibitors on circulating PCSK9 levels in HIV-infected antiretroviral-naive patients from an ongoing prospective cohort Franck Boccara,Mathilde Ghislain,Laurence Meyer,Cecile Goujard,Cedric Le Mayet al. AIDS. Official journal of the international AIDS Society, 2017, Equipe IV, 31 (17), pp.2367--2376. ⟨10.1097/QAD.0000000000001633⟩ Article dans une revue hal-01832935v1
Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice Audrey Ayer,Frederic Borel,Francois Moreau,Xavier Prieur,Michel Neunlistet al. Journal of visualized experiments : JoVE, 2017, Equipe IV, 121, ⟨10.3791/54905⟩ Article dans une revue hal-01832948v1
Circulating PCSK9 levels in acute coronary syndrome: Results from the PC-SCA-9 prospective study Bertrand Cariou,P. Guérin,Cedric Le May,V. Letocart,L. Arnaudet al. Diabetes & Metabolism, 2017, Equipe IV, 43 (6), pp.529--535. ⟨10.1016/j.diabet.2017.07.009⟩ Article dans une revue istex hal-01832940v1
E2F1 inhibits circulating cholesterol clearance by regulating Pcsk9 expression in the liver Qiuwen Lai,Albert Giralt,Cedric Le May,Lianjun Zhang,Bertrand Cariouet al. JCI Insight, 2017, Equipe IV, 2 (10), ⟨10.1172/jci.insight.89729⟩ Article dans une revue hal-01828864v1
PPARγ Modulates Long Chain Fatty Acid Processing in the Intestinal Epithelium Kalina Duszka,Matej Oresic,Cedric Le May,Jürgen König,Walter Wahli International Journal of Molecular Sciences, 2017, Equipe IV, 18 (12), ⟨10.3390/ijms18122559⟩ Article dans une revue hal-01832934v1
The Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin Prevents Cardiomyopathy in a Diabetic Lipodystrophic Mouse Model Michael Joubert,Benoît Jagu,David Montaigne,Xavier Marechal,Angela Tesseet al. Diabetes, 2017, Equipe IIa Equipe III Equipe IV, 66 (4), pp.1030--1040. ⟨10.2337/db16-0733⟩ Article dans une revue hal-01832151v1
Impact of Sleeve Gastrectomy on Intestinal Permeability in Diet-Induced Obese Mice Claire Blanchard,Audrey Ayer,Julien Chevalier,François Moreau,Jean-Paul Pais de Barroset al. Surgery for Obesity and Related Diseases, 2016, 12 (7), pp.S10 - S11. ⟨10.1016/j.soard.2016.08.043⟩ Article dans une revue hal-01503082v1
Retrograde cholesterol transport in the human Caco-2/TC7 cell line: a model to study trans-intestinal cholesterol excretion in atherogenic and diabetic dyslipidemia Camille Dugardin,Olivier Briand,Véronique Touche,Marleen Schonewille,François Moreauet al. Acta Diabetologica, 2016, 54 (2), pp.191-199. ⟨10.1007/s00592-016-0936-z⟩ Article dans une revue hal-03013305v1
FGF21 Improves the Adipocyte Dysfunction Related to Seipin Deficiency Lucile Dollet,Clara Levrel,Tamer Coskun,Soazig Le Lay,Cedric Le Mayet al. Diabetes, 2016, Equipe 5, 65 (11), pp.3410--3417. ⟨10.2337/db16-0327⟩ Article dans une revue hal-01831750v1
Role of PCSK9 beyond liver involvement Bertrand Cariou,Karim Si-Tayeb,Cedric Le May Current Opinion in Lipidology, 2015, Equipe 5, 26 (3), pp.155--161. ⟨10.1097/MOL.0000000000000180⟩ Article dans une revue hal-01830980v1
The loss-of-function PCSK9 p.R46L genetic variant does not alter glucose homeostasis Amélie Bonnefond,Loïc Yengo,Cedric Le May,Fréderic Fumeron,Michel Marreet al. Diabetologia, 2015, Equipe 5, 58 (9), pp.2051--2055. ⟨10.1007/s00125-015-3659-8⟩ Article dans une revue hal-01830978v1
Letter From Le May and Cariou Regarding Article, &quot;Proprotein Convertase Subtilisin Kexin Type 9 Promotes Intestinal Overproduction of Triglyceride-Rich Apolipoprotein B Lipoproteins Through Both Low-Density Lipoprotein Receptor-Dependent and -Independent Mechanisms Cedric Le May,Bertrand Cariou EUCOR Newsletter, 2015, Equipe 5, 131 (18), pp.e427--e427. ⟨10.1161/CIRCULATIONAHA.114.011697⟩ Article dans une revue hal-01830973v1
PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension Jean-Mathieu Berger,Nathalie Vaillant,Cedric Le May,Carolina Calderon,Jeremy Brégeonet al. Atherosclerosis, 2015, Equipe 2 Equipe 5, 239 (1), pp.252--259. ⟨10.1016/j.atherosclerosis.2015.01.012⟩ Article dans une revue istex hal-01830594v1
Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia Karim Si-Tayeb,Salam Idriss,Benoite Champon,Amandine Caillaud,Matthieu Pichelinet al. Disease Models & Mechanisms, 2015, ⟨10.1242/dmm.022277⟩ Article dans une revue hal-01233240v1
Preserved adrenal function in fully PCSK9-deficient subject Bertrand Cariou,Isabelle Benoit,Cedric Le May International Journal of Cardiology, 2014, 176 (2), pp.499-500. ⟨10.1016/j.ijcard.2014.07.057⟩ Article dans une revue hal-03013322v1
L’excrétion trans -intestinale de cholestérol (TICE) Claire Blanchard,François Moreau,Bertrand Cariou,Cedric Le May Médecine/Sciences, 2014, 30 (10), pp.896-901. ⟨10.1051/medsci/20143010017⟩ Article dans une revue hal-03013320v1
Congenital Lipodystrophies and Dyslipidemias Xavier Prieur,Cedric Le May,Jocelyne Magré,Bertrand Cariou Current Atherosclerosis Reports, 2014, 16 (9), pp.437. ⟨10.1007/s11883-014-0437-x⟩ Article dans une revue hal-03013323v1
Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1 Cedric Le May,Jean Mathieu Berger,Anne Lespine,Bruno Pillot,Xavier Prieuret al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2013, 33 (7), pp.1484-1493. ⟨10.1161/ATVBAHA.112.300263⟩ Article dans une revue hal-03013326v1
Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1 Cedric Le May,Jean Mathieu Berger,Anne Lespine,Bruno Pillot,Xavier Prieuret al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2013, 33 (7), pp.1484 - 1493. ⟨10.1161/ATVBAHA.112.300263⟩ Article dans une revue hal-02650431v1
Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice X. Prieur,L. Dollet,M. Takahashi,M. Nemani,B. Pillotet al. Diabetologia, 2013, 56 (8), pp.1813-1825. ⟨10.1007/s00125-013-2926-9⟩ Article dans une revue hal-03013324v1
Plasma PCSK9 concentrations during an oral fat load and after short term high-fat, high-fat high-protein and high-fructose diets. Bertrand Cariou,Cédric Langhi,Maëlle Le Bras,Murielle Bortolotti,Kim-Anne Lêet al. Nutrition and Metabolism, 2013, 10 (1), pp.4. ⟨10.1186/1743-7075-10-4⟩ Article dans une revue inserm-00778104v1
Clinical aspects of PCSK9 Bertrand Cariou,Cedric Le May,Philippe Costet Atherosclerosis, 2011, 216 (2), pp.258-265. ⟨10.1016/j.atherosclerosis.2011.04.018⟩ Article dans une revue istex hal-03013330v1
Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes Joseph Tiano,Viviane Delghingaro-Augusto,Cedric Le May,Suhuan Liu,Meenakshi Kawet al. Journal of Clinical Investigation, 2011, 121 (8), pp.3331-3342. ⟨10.1172/JCI44564⟩ Article dans une revue hal-03013329v1
Extranuclear estrogen receptor- stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis W. Wong,J. Tiano,S. Liu,S. Hewitt,Cedric Le Mayet al. Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (29), pp.13057-13062. ⟨10.1073/pnas.0914501107⟩ Article dans une revue hal-03013333v1
Association between plasma PCSK9 and gamma-glutamyl transferase levels in diabetic patients Bertrand Cariou,Maëlle Le Bras,Cédric Langhi,Cedric Le May,Béatrice Guyomarc’h-Delasalleet al. Atherosclerosis, 2010, 211 (2), pp.700-702. ⟨10.1016/j.atherosclerosis.2010.04.015⟩ Article dans une revue istex hal-03013334v1
PCSK9 is expressed in pancreatic δ-cells and does not alter insulin secretion Cédric Langhi,Cedric Le May,Valéry Gmyr,Brigitte Vandewalle,Julie Kerr-Conteet al. Biochemical and Biophysical Research Communications, 2009, 390 (4), pp.1288-1293. ⟨10.1016/j.bbrc.2009.10.138⟩ Article dans une revue istex hal-03013335v1
Proprotein Convertase Subtilisin Kexin Type 9 Null Mice Are Protected From Postprandial Triglyceridemia Cedric Le May,Cédric Le May,Sanae Kourimate,Cédric Langhi,Maud Chétiveauxet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2009, 29 (5), pp.684-690. ⟨10.1161/ATVBAHA.108.181586⟩ Article dans une revue hal-03013340v1
PCSK9 Dominant Negative Mutant Results in Increased LDL Catabolic Rate and Familial Hypobetalipoproteinemia Cedric Le May,Bertrand Cariou,Khadija Ouguerram,Yassine Zaïr,Raphael Gueroiset al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2009, 29 (12), pp.2191-2197. ⟨10.1161/ATVBAHA.109.194191⟩ Article dans une revue hal-03013337v1
Proprotein convertase subtilisin kexin type 9 null mice are protected from postprandial triglyceridemia Cedric Le May,Sanae Kourimate,Cédric Langhi,Maud Chétiveaux,Anne Jarryet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2009, 29 (5), pp.684-690. ⟨10.1161/ATVBAHA.108.181586⟩ Article dans une revue hal-02661775v1
Importance of Extranuclear Estrogen Receptor- and Membrane G Protein-Coupled Estrogen Receptor in Pancreatic Islet Survival S. Liu,Cedric Le May,W. P.S. Wong,R. Ward,D. Clegget al. Diabetes, 2009, 58 (10), pp.2292-2302. ⟨10.2337/db09-0257⟩ Article dans une revue hal-03013339v1
Involvement of ZIP/p62 in the regulation of PPARα transcriptional activity by p38-MAPK Claire Diradourian,Cedric Le May,Michèle Caüzac,Jean Girard,Anne-Françoise Burnolet al. BBA - Biochimica et Biophysica Acta, 2008, 1781 (5), pp.239-244. ⟨10.1016/j.bbalip.2008.02.002⟩ Article dans une revue istex hal-03013344v1
Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes Cédric Langhi,Cedric Le May,Sanae Kourimate,Sandrine Caron,Bart Staelset al. FEBS Letters, 2008, 582 (6), pp.949-955. ⟨10.1016/j.febslet.2008.02.038⟩ Article dans une revue hal-03013345v1
Dual Mechanisms for the Fibrate-mediated Repression of Proprotein Convertase Subtilisin/Kexin Type 9 Sanae Kourimate,Cedric Le May,Cédric Langhi,Anne Laure Jarnoux,Khadija Ouguerramet al. Journal of Biological Chemistry, 2008, 283 (15), pp.9666-9673. ⟨10.1074/jbc.M705831200⟩ Article dans une revue hal-03013347v1
Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice Cedric Le May,K. Chu,M. Hu,C. Ortega,E. Simpsonet al. Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (24), pp.9232-9237. ⟨10.1073/pnas.0602956103⟩ Article dans une revue hal-03013348v1
Fatty Acids Induce L-CPT I Gene Expression through a PPARα-Independent Mechanism in Rat Hepatoma Cells Cedric Le May,Cédric Le May,Michèle Caüzac,Claire Diradourian,Dominique Perdereauet al. Journal of Nutrition, 2005, 135 (10), pp.2313-2319. ⟨10.1093/jn/135.10.2313⟩ Article dans une revue hal-03013352v1
PAX4 gene variations predispose to ketosis-prone diabetes Cedric Le May,Franck Mauvais-Jarvis,Stuart Smith,Cédric Le May,Suzanne Lealet al. Human Molecular Genetics, 2004, 13 (24), pp.3151-3159. ⟨10.1093/hmg/ddh341⟩ Article dans une revue hal-03013354v1
Control of Gene Expression by Fatty Acids Cedric Le May,Jean-Paul Pégorier,Cédric Le May,Jean Girard Journal of Nutrition, 2004, 134 (9), pp.2444S-2449S. ⟨10.1093/jn/134.9.2444S⟩ Article dans une revue hal-03013355v1
Antidiabetic actions of estrogen: Insight from human and genetic mouse models Cedric Le May,Jean-Francois Louet,Cedric Lemay,Franck Mauvais-Jarvis Current Atherosclerosis Reports, 2004, 6 (3), pp.180-185. ⟨10.1007/s11883-004-0030-9⟩ Article dans une revue hal-03013357v1
Regulation of liver carnitine palmitoyltransferase I gene expression by hormones and fatty acids J.-F. Louet,Cedric Le May,J.-P. Pégorier,J.-F. Decaux,J. Girard Biochemical Society Transactions, 2001, 29 (2), pp.310. ⟨10.1042/0300-5127:0290310⟩ Article dans une revue hal-03013360v1
Reduced hepatic fatty acid oxidation in fasting PPARα null mice is due to impaired mitochondrial hydroxymethylglutaryl-CoA synthase gene expression Cedric Le May,Thierry Pineau,Karine Bigot,Claude Kohl,Jean Girardet al. FEBS Letters, 2000, 475 (3), pp.163-166. ⟨10.1016/s0014-5793(00)01648-3⟩ Article dans une revue hal-03013361v1

Pré-publication, Document de travail (1)

Tripartite ER-Mitochondria-Lipid Droplets contact sites control adipocyte metabolic flexibility Marie Palard,Gilliane Chadeuf,Maxime Carpentier,Samuel Frey,Mikael Croyalet al. 2025 Pré-publication, Document de travail hal-05376862v1

Brevet (1)

LIPC variant in the treatment of hypercholesterolemia and atherosclerotic cardiovascular disease Bertrand Cariou,Cedric Le May,Wieneke Dijk,Philippe Moulin,Mathilde Di-Filippo Charcosset France, Patent n° : PCT/FR2023/050714. 2023 Brevet hal-05199054v1

Communication dans un congrès (1)

Plasma cholesterol is excreted in the feces of patients with complete common bile duct obstruction : in vivo evidence for tice pathway in humans François Moreau,Claire Blanchard,Christophe Perret,Laurent Flet,Frédéric Douaneet al. 85th Congress of the European-Atherosclerosis-Society (EAS), European Atherosclerosis Society. SWE., Apr 2017, Prague, Czech Republic. pp.2 Communication dans un congrès hal-02737439v1