Céline Crauste

Documents

Publications

	A novel lipophenol quercetin derivative to prevent macular degeneration: Intravenous and oral formulations for preclinical pharmacological evaluation Maxime Vincent , Jordan Lehoux , Claire Desmarty , Esperance Moine , Philippe Legrand International Journal of Pharmaceutics, 2024, 651, pp.123740. ⟨10.1016/j.ijpharm.2023.123740⟩ Journal articles hal-04386862v1
	Overview of alkyl quercetin lipophenol synthesis and its protective effect against carbonyl stress involved in neurodegeneration Léa Otaegui , Jordan Lehoux , Leo Martin , Laurent Givalois , Thierry Durand Organic & Biomolecular Chemistry, In press, ⟨10.1039/d4ob00066h⟩ Journal articles hal-04520041v1
	Hydroxytyrosol fatty acid esters as new candidate markers for detecting olive oil inadequate storage conditions by UHPLC-QqQ-MS/MS Sonia Medina , David Auñón , Jordan Lehoux , Thierry Durand , Céline Crauste Microchemical Journal, 2022, 181, pp.107656. ⟨10.1016/j.microc.2022.107656⟩ Journal articles hal-04102912v1
	Formulation and Evaluation of SNEDDS Loaded with Original Lipophenol for the Oral Route to Prevent Dry AMD and Stragardt’s Disease Maxime Vincent , Laurianne Simon , Philippe Brabet , Philippe Legrand , Christophe Dorandeu Pharmaceutics, 2022, 14 (5), pp.1029. ⟨10.3390/pharmaceutics14051029⟩ Journal articles hal-03681400v1
	Synthesis of Fatty Acid Bioconjugates and Related Derivatives Céline Crauste , Jean‐marie Galano , Alexandre Guy , Jordan Lehoux , Thierry Durand European Journal of Organic Chemistry, 2022, 2022 (21), pp.e202101502. ⟨10.1002/ejoc.202101502⟩ Journal articles hal-03692908v1
	Unravelling the capacity of hydroxytyrosol and its lipophenolic derivates to modulate the H2O2-induced isoprostanoid profile of THP-1 monocytes by UHPLC-QqQ-MS/MS lipidomic workflow Carolina Alemán-Jiménez , Raúl Domínguez-Perles , Federico Fanti , Juana Gallego-Gómez , Agustín Simonelli-Muñoz Microchemical Journal, 2021, 170, pp.106703. ⟨10.1016/j.microc.2021.106703⟩ Journal articles hal-03374014v1
	Fatty Acid Hydroxytyrosyl Esters of Olive Oils Are Bioaccessible According to Simulated In Vitro Gastrointestinal Digestion: Unraveling the Role of Digestive Enzymes on Their Stability Carolina Alemán-Jiménez , Raúl Domínguez-Perles , Juana I. Gallego-Gómez , Agustín Simonelli-Muñoz , Espérance Moine Journal of Agricultural and Food Chemistry, 2021, 69 (47), pp.14165-14175. ⟨10.1021/acs.jafc.1c05373⟩ Journal articles hal-04102919v1
	New lipophenols prevent carbonyl and oxidative stresses involved in macular degeneration Espérance Moine , Manel Boukhallat , David Cia , Nathalie Jacquemot , Laurent Guillou Free Radical Biology and Medicine, 2021, 162, pp.367-382. ⟨10.1016/j.freeradbiomed.2020.10.316⟩ Journal articles hal-04256742v1
	Dissecting the antibacterial activity of oxadiazolone-core derivatives against Mycobacterium abscessus Abdeldjalil Madani , Ivy Mallick , Alexandre Guy , Céline Crauste , Thierry Durand PLoS ONE, 2020, 15 (9), pp.e0238178. ⟨10.1371/journal.pone.0238178⟩ Journal articles hal-02950695v1
	Targeted lipidomics profiling reveals the generation of hydroxytyrosol-fatty acids in hydroxytyrosol-fortified oily matrices: new analytical methodology and cytotoxicity evaluation Sonia Medina , Raúl Dominguez-Perles , David Auñon , Espérance Moine , Thierry Durand Journal of Agricultural and Food Chemistry, 2020, ⟨10.1021/acs.jafc.0c01938⟩ Journal articles hal-04102923v1
	Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy Nicolas Taveau , Aurélie Cubizolle , Laurent Guillou , Nicolas Pinquier , Espérance Moine Experimental & Molecular Medicine, 2020, 52 (7), pp.1090-1101. ⟨10.1038/s12276-020-0460-7⟩ Journal articles hal-04256818v1
	Isopropyl‐phloroglucinol‐DHA protects outer retinal cells against lethal dose of all‐ trans ‐retinal Aurelie Cubizolle , David Cia , Espérance Moine , Nathalie Jacquemot , Laurent Guillou Journal of Cellular and Molecular Medicine, 2020, 24 (9), pp.5057-5069. ⟨10.1111/jcmm.15135⟩ Journal articles hal-02593070v1
	New lipophenols prevent carbonyl and oxidative stresses involved in macular degeneration Espérance Moine , Manel Boukhallat , David Cia , Nathalie Jacquemot , Laurent Guillou Free Radical Biology and Medicine, 2020, ⟨10.1016/j.freeradbiomed.2020.10.316⟩ Journal articles hal-03067208v1
	Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy Nicolas Taveau , Aurélie Cubizolle , Laurent Guillou , Nicolas Pinquier , Espérance Moine Experimental & Molecular Medicine, 2020, 52, pp.1090 - 1101. ⟨10.1038/s12276-020-0460-7⟩ Journal articles hal-03071488v1
	Combination of Lutein and Zeaxanthin, and DHA Regulated Polyunsaturated Fatty Acid Oxidation in H2O2-Stressed Retinal Cells Ho Hang Leung , Jean-Marie Galano , Céline Crauste , Thierry Durand , Jetty Chung-Yung Lee Neurochemical Research, 2020, 45 (5), pp.1007-1019. ⟨10.1007/s11064-020-02994-4⟩ Journal articles hal-02592871v1
	Bis-allylic Deuterated DHA Alleviates Oxidative Stress in Retinal Epithelial Cells Mélissa Rosell , Martin Giera , Philippe Brabet , Mikhail S Shchepinov , Michel Guichardant Antioxidants , 2019, 8 (10), pp.447. ⟨10.3390/antiox8100447⟩ Journal articles hal-02308917v1
	Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis Phuong Chi Nguyen , Vincent Delorme , Anaïs Benarouche , Alexandre Guy , Valérie Landry Bioorganic Chemistry, 2018, 81, pp.414-424. ⟨10.1016/j.bioorg.2018.08.025⟩ Journal articles hal-01875577v1
	New Lipophenol Antioxidants Reduce Oxidative Damage in Retina Pigment Epithelial Cells Espérance Moine , Philippe Brabet , Laurent Guillou , Thierry Durand , Joseph Vercauteren Antioxidants , 2018, 7 (12), pp.197. ⟨10.3390/antiox7120197⟩ Journal articles hal-02308918v1
	LipG a bifunctional phospholipase/thioesterase involved in mycobacterial envelope remodeling Pierre Santucci , Vanessa Point , Isabelle Poncin , Alexandre Guy , Céline Crauste Bioscience Reports, 2018, 38 (6), pp.BSR20181953. ⟨10.1042/BSR20181953⟩ Journal articles hal-01990097v1
	Resveratrol-Linoleate protects from exacerbated endothelial permeability via a drastic inhibition of the MMP-9 activity Aly Shamseddin , Céline Crauste , Erwann Durand , Pierre Villeneuve , Grégor Dubois Bioscience Reports, 2018, 38 (4), pp.BSR20171712. ⟨10.1042/BSR20171712⟩ Journal articles hal-01935636v1
	Resveratrol formulated with a natural deep eutectic solvent inhibits active matrix metalloprotease-9 in hormetic conditions. Aly Shamseddin , Céline Crauste , Erwann Durand , Pierre Villeneuve , Gregor Dubois European Journal of Lipid Science and Technology, 2017, pp.1700171. ⟨10.1002/ejlt.201700171⟩ Journal articles hal-02308915v1
	Total Syntheses of Two bis-Allylic-Deuterated DHA Analogues Mélissa Rosell , Maxime Villa , Thierry Durand , Jean-Marie Galano , Joseph Vercauteren Asian Journal of Organic Chemistry, 2017, 6 (3), pp.322 - 334. ⟨10.1002/ajoc.201600565⟩ Journal articles hal-01622325v1
	Extra Virgin Olive Oil Reduced Polyunsaturated Fatty Acid and Cholesterol Oxidation in Rodent Liver: Is This Accounted for Hydroxytyrosol-Fatty Acid Conjugation? Yiu Yiu Lee , Céline Crauste , Hualin Wang , Ho Hang Leung , Joseph Vercauteren Chemical Research in Toxicology, 2016, 29 (10), pp.1689-1698. ⟨10.1021/acs.chemrestox.6b00214⟩ Journal articles hal-01622331v1
	Phloroglucinol protects retinal pigment epithelium and photoreceptor against all-trans-retinal-induced toxicity and inhibits A2E formation David Cia , Aurelie Cubizolle , Céline Crauste , Nathalie Jacquemot , Laurent Guillou Journal of Cellular and Molecular Medicine, 2016, 20 (9), pp.1651-1663. ⟨10.1111/jcmm.12857⟩ Journal articles hal-01871969v1
	Omega-3 polyunsaturated lipophenols, how and why? Céline Crauste , Mélissa Rosell , Thierry Durand , Joseph Vercauteren Biochimie, 2015, ⟨10.1016/j.biochi.2015.07.018⟩ Journal articles hal-02309676v1
	Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking Approaches Baptiste Villemagne , Marion Flipo , Nicolas Blondiaux , Celine Crauste , Sandra Malaquin Journal of Medicinal Chemistry, 2014, 57 (11), pp.4876-4888. ⟨10.1021/jm500422b⟩ Journal articles hal-02309782v1
	Unconventional surface plasmon resonance signals reveal quantitative inhibition of transcriptional repressor EthR by synthetic ligands Céline Crauste , Nicolas Willand , Baptiste Villemagne , Marion Flipo , Eve Willery Analytical Biochemistry, 2014, 452, pp.54-66. ⟨10.1016/j.ab.2014.02.011⟩ Journal articles hal-02309788v1
	Synthesis and Evaluation of Polyunsaturated Fatty Acid-Phenol Conjugates as Anti-Carbonyl-Stress Lipophenols Céline Crauste , Claire Vigor , Philippe Brabet , Madeleine Picq , Michel Lagarde European Journal of Organic Chemistry, 2014, 2014 (21), pp.4548-4561. ⟨10.1002/ejoc.201402282⟩ Journal articles hal-02309885v1
	Tuberculosis: The drug development pipeline at a glance Baptiste Villemagne , Céline Crauste , Marion Flipo , Alain R. Baulard , Benoit Déprez European Journal of Medicinal Chemistry, 2012, 51, pp.1-16. ⟨10.1016/j.ejmech.2012.02.033⟩ Journal articles hal-02309791v1
	Synthesis of 2′,3′-Dideoxynucleoside Phosphoesters Using H-Phosphonate Chemistry on Soluble Polymer Support Céline Crauste , Christian Périgaud , Suzanne Peyrottes Journal of Organic Chemistry, 2011, 76 (3), pp.997-1000. ⟨10.1021/jo1022958⟩ Journal articles hal-02309881v1
	Asymmetric Synthesis of New β-Lactam Lipopeptides as Bacterial Signal Peptidase I Inhibitors Céline Crauste , Matheus Froeyen , Jozef Anné , Piet Herdewijn European Journal of Organic Chemistry, 2011, 2011 (19), pp.3437-3449. ⟨10.1002/ejoc.201100148⟩ Journal articles hal-02309796v1
	Insights into the Soluble PEG-Supported Synthesis of Cytosine-Containing Nucleoside 5′-Mono-, Di-, and Triphosphates Céline Crauste , Christian Périgaud , Suzanne Peyrottes Journal of Organic Chemistry, 2009, 74 (23), pp.9165-9172. ⟨10.1021/jo901931z⟩ Journal articles hal-02309892v1
	Development of a sensitive and selective LC/MS/MS method for the simultaneous determination of intracellular 1-beta-d-arabinofuranosylcytosine triphosphate (araCTP), cytidine triphosphate (CTP) and deoxycytidine triphosphate (dCTP) in a human follicular lymphoma cell line Céline Crauste , Isabelle Lefebvre , Michael Hovaneissian , Jean Yves Puy , Béatrice Roy Journal of Chromatography B Biomedical Sciences and Applications, 2009, 877 (14-15), pp.1417-1425. ⟨10.1016/j.jchromb.2009.02.071⟩ Journal articles hal-02309584v1
	Magnesium(II)-coordinated Claisen rearrangement: a direct approach towards ulosonic acid derivatives Claude Grison , Tomasz Krzysztof Olszewski , Céline Crauste , Alain Fruchier , Claude Didierjean Tetrahedron Letters, 2006, 47 (37), pp.6583-6586. ⟨10.1016/j.tetlet.2006.07.022⟩ Journal articles hal-02309971v1

	Lipophenols as new therapeutics toward retinal degeneration: in vitro and in vivo pharmacological studies Espérance Moine , Nicolas Taveau , Maxime Vincent , Laurent Guillou , Sylvie Bégu Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), May 2020, En ligne (Etats-Unis), France. pp.4939 Conference papers hal-04570694v1

	Deciphering the physiological role of serine enzymes involved in mycobacterial lipid metabolism using activity-based protein profiling Romain Avellan , Morgane Sarrazin , Christopher D Spilling , Céline Crauste , Stéphane Canaan Biology of Mycobacterial Lipids, 2022, ⟨10.1016/B978-0-323-91948-7.00001-4⟩ Book sections hal-03705053v1

Céline Crauste

Publications

A novel lipophenol quercetin derivative to prevent macular degeneration: Intravenous and oral formulations for preclinical pharmacological evaluation

Overview of alkyl quercetin lipophenol synthesis and its protective effect against carbonyl stress involved in neurodegeneration

Hydroxytyrosol fatty acid esters as new candidate markers for detecting olive oil inadequate storage conditions by UHPLC-QqQ-MS/MS

Formulation and Evaluation of SNEDDS Loaded with Original Lipophenol for the Oral Route to Prevent Dry AMD and Stragardt’s Disease

Synthesis of Fatty Acid Bioconjugates and Related Derivatives

Unravelling the capacity of hydroxytyrosol and its lipophenolic derivates to modulate the H2O2-induced isoprostanoid profile of THP-1 monocytes by UHPLC-QqQ-MS/MS lipidomic workflow

Fatty Acid Hydroxytyrosyl Esters of Olive Oils Are Bioaccessible According to Simulated In Vitro Gastrointestinal Digestion: Unraveling the Role of Digestive Enzymes on Their Stability

New lipophenols prevent carbonyl and oxidative stresses involved in macular degeneration

Dissecting the antibacterial activity of oxadiazolone-core derivatives against Mycobacterium abscessus

Targeted lipidomics profiling reveals the generation of hydroxytyrosol-fatty acids in hydroxytyrosol-fortified oily matrices: new analytical methodology and cytotoxicity evaluation

Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy

Isopropyl‐phloroglucinol‐DHA protects outer retinal cells against lethal dose of all‐ trans ‐retinal

New lipophenols prevent carbonyl and oxidative stresses involved in macular degeneration

Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy

Combination of Lutein and Zeaxanthin, and DHA Regulated Polyunsaturated Fatty Acid Oxidation in H2O2-Stressed Retinal Cells

Bis-allylic Deuterated DHA Alleviates Oxidative Stress in Retinal Epithelial Cells

Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis

New Lipophenol Antioxidants Reduce Oxidative Damage in Retina Pigment Epithelial Cells

LipG a bifunctional phospholipase/thioesterase involved in mycobacterial envelope remodeling

Resveratrol-Linoleate protects from exacerbated endothelial permeability via a drastic inhibition of the MMP-9 activity

Resveratrol formulated with a natural deep eutectic solvent inhibits active matrix metalloprotease-9 in hormetic conditions.

Total Syntheses of Two bis-Allylic-Deuterated DHA Analogues

Extra Virgin Olive Oil Reduced Polyunsaturated Fatty Acid and Cholesterol Oxidation in Rodent Liver: Is This Accounted for Hydroxytyrosol-Fatty Acid Conjugation?

Phloroglucinol protects retinal pigment epithelium and photoreceptor against all-trans-retinal-induced toxicity and inhibits A2E formation

Omega-3 polyunsaturated lipophenols, how and why?

Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking Approaches

Unconventional surface plasmon resonance signals reveal quantitative inhibition of transcriptional repressor EthR by synthetic ligands

Synthesis and Evaluation of Polyunsaturated Fatty Acid-Phenol Conjugates as Anti-Carbonyl-Stress Lipophenols

Tuberculosis: The drug development pipeline at a glance

Synthesis of 2′,3′-Dideoxynucleoside Phosphoesters Using H-Phosphonate Chemistry on Soluble Polymer Support

Asymmetric Synthesis of New β-Lactam Lipopeptides as Bacterial Signal Peptidase I Inhibitors

Insights into the Soluble PEG-Supported Synthesis of Cytosine-Containing Nucleoside 5′-Mono-, Di-, and Triphosphates

Development of a sensitive and selective LC/MS/MS method for the simultaneous determination of intracellular 1-beta-d-arabinofuranosylcytosine triphosphate (araCTP), cytidine triphosphate (CTP) and deoxycytidine triphosphate (dCTP) in a human follicular lymphoma cell line

Magnesium(II)-coordinated Claisen rearrangement: a direct approach towards ulosonic acid derivatives

Lipophenols as new therapeutics toward retinal degeneration: in vitro and in vivo pharmacological studies

Deciphering the physiological role of serine enzymes involved in mycobacterial lipid metabolism using activity-based protein profiling