Christina Sizun

Identifiants chercheurs

IdHAL :

christina-sizun

ORCID :

0000-0002-5760-2614

IdRef :

184765625

Présentation

Publications

Article dans une revue (35)

Hospital-Compounded Birabresib Capsules for NUT Carcinoma: A Quality- and Risk-Based CMC Strategy Maxime Annereau,François-Xavier Legrand,Maria Virginia Sánchez-Becerra,Stéphanie Ramos,Françoise Duperrayet al. Pharmaceutical Research, 2026, ⟨10.1007/s11095-026-04081-9⟩ Article dans une revue hal-05567574v1
The ISC machinery assembles [2Fe–2S] clusters by formation and fusion of [1Fe–1S] precursors Sylvain Gervason,Rafal Dutkiewicz,Kristian Want,Rania Benazza,Rémi Mor-Gautieret al. Nature Chemical Biology, 2025, 21 (5), pp.767-778. ⟨10.1038/s41589-024-01818-8⟩ Article dans une revue hal-05348439v1
Cyclodextrin-based formulations for delivering broad-spectrum nerve agent antidote to the central nervous system: stability, physicochemical characterization and application in a human blood–brain barrier model Léa Thiberville,Vincent Faivre,Christina Sizun,Marie-Pierre Dehouck,Christophe Landryet al. International Journal of Pharmaceutics, 2025, 674, pp.125505. ⟨10.1016/j.ijpharm.2025.125505⟩ Article dans une revue hal-05017548v1
A dual interaction between RSV NS1 and MED25 ACID domain reshapes antiviral responses Célia Ait Mouhoub,Jiawei Dong,Magali Noiray,Jenna Fix,Stepanka Nedvedovaet al. PLoS Pathogens, 2025, 21 (9), pp.e1012930. ⟨10.1371/journal.ppat.1012930⟩ Article dans une revue hal-05265108v1
Development of nanoparticles based on amphiphilic cyclodextrins for the delivery of active substances Luc Augis,Ingeborg Nerbø Reiten,Jan-Lukas Førde,Juan Casas-Solvas,Christina Sizunet al. International Journal of Pharmaceutics, 2024, 651, pp.123723. ⟨10.1016/j.ijpharm.2023.123723⟩ Article dans une revue hal-04366812v1
Hydrophobic binary mixtures containing amphotericin B as lipophilic solutions for the treatment of cutaneous leishmaniasis Luc Augis,Canh Hung Nguyen,Cécile Ciseran,András Wacha,Françoise Mercier-Noméet al. International Journal of Pharmaceutics, 2024, 662, pp.124486. ⟨10.1016/j.ijpharm.2024.124486⟩ Article dans une revue hal-04660063v1
Structural transitions in TCTP tumor protein upon binding to the anti-apoptotic protein family member Mcl-1 Florian Malard,Christina Sizun,Aurélien Thureau,Ludovic Carlier,Ewen Lescop Journal of Biological Chemistry, 2023, 299 (7), pp.104830. ⟨10.1016/j.jbc.2023.104830⟩ Article dans une revue hal-04208651v1
Hardening of Respiratory Syncytial Virus Inclusion Bodies by Cyclopamine Proceeds through Perturbation of the Interactions of the M2-1 Protein with RNA and the P Protein Cédric Diot,Charles-Adrien Richard,Jennifer Risso-Ballester,Davy Martin,Jenna Fixet al. International Journal of Molecular Sciences, 2023, 24 (18), pp.13862. ⟨10.3390/ijms241813862⟩ Article dans une revue hal-04239191v1
Investigation of the Fuzzy Complex between RSV Nucleoprotein and Phosphoprotein to Optimize an Inhibition Assay by Fluorescence Polarization Silva Khodjoyan,Deborha Morissette,Fortune Hontonnou,Luis Checa Ruano,Charles-Adrien Richardet al. International Journal of Molecular Sciences, 2023, 24 (1), pp.569. ⟨10.3390/ijms24010569⟩ Article dans une revue hal-04012024v1
Biophysical Reviews’ “Meet the Editors Series”: a profile of Christina Sizun Christina Sizun Biophysical Reviews, 2023, 15 (3), pp.301-304. ⟨10.1007/s12551-023-01071-8⟩ Article dans une revue hal-04256992v1
Iron insertion at the assembly site of the ISCU scaffold protein is a conserved process initiating Fe–S cluster biosynthesis Batoul Srour,Sylvain Gervason,Maren Hellen Hoock,Beata Monfort,Kristian Wantet al. Journal of the American Chemical Society, 2022, 144 (38), pp.17496 - 17515. ⟨10.1021/jacs.2c06338⟩ Article dans une revue hal-03837292v1
Respiratory Syncytial Virus NS1 Protein Targets the Transactivator Binding Domain of MED25 Jiawei Dong,Vincent Basse,Maxime Bierre,Andressa Peres de Oliveira,Pierre-Olivier Vidalainet al. Journal of Molecular Biology, 2022, 434 (19), pp.167763. ⟨10.1016/j.jmb.2022.167763⟩ Article dans une revue hal-03834936v1
Interactions between the nucleoprotein and the phosphoprotein of pneumoviruses: structural insight for rational design of antivirals Hortense Decool,Lorène Gonnin,Irina Gutsche,Christina Sizun,Jean-François Eléouëtet al. Viruses, 2021, 13 (12), pp.2449. ⟨10.3390/v13122449⟩ Article dans une revue hal-03520624v1
Tetramerization of Phosphoprotein Is Essential for Respiratory Syncytial Virus Budding while Its N-Terminal Region Mediates Direct Interactions with the Matrix Protein Monika Bajorek,Marie Galloux,Charles-Adrien Richard,Or Szekely,Rina Rosenzweiget al. Journal of Virology, 2021, 95, ⟨10.1128/jvi.02217-20⟩ Article dans une revue hal-04635668v2
A Structural and Dynamic Analysis of the Partially Disordered Polymerase-Binding Domain in RSV Phosphoprotein Christophe Cardone,Claire-Marie Caseau,Benjamin Bardiaux,Aurélien Thureaux,Marie Gallouet al. Biomolecules, 2021, 11 (8), ⟨10.3390/biom11081225⟩ Article dans une revue hal-03321817v1
Pneumoviral Phosphoprotein, a Multidomain Adaptor-Like Protein of Apparent Low Structural Complexity and High Conformational Versatility Christophe Cardone,Claire-Marie Caseau,Nelson Pereira,Christina Sizun International Journal of Molecular Sciences, 2021, 22 (4), pp.1537. ⟨10.3390/ijms22041537⟩ Article dans une revue hal-03319031v1
Cyclodextrin Complexation Studies as the First Step for Repurposing of Chlorpromazine Zhiqiang Wang,David Landy,Christina Sizun,Christine Cézard,Audrey Solgadiet al. International Journal of Pharmaceutics, 2020, 584, pp.119391. ⟨10.1016/j.ijpharm.2020.119391⟩ Article dans une revue hal-02885940v1
A seven-residue deletion in PrP leads to generation of a spontaneous prion formed from C-terminal C1 fragment of PrP Carola Munoz-Montesino,Djabir Larkem,Clément Barbereau,Angélique Igel-Egalon,Sandrine Truchetet al. Journal of Biological Chemistry, 2020, 295 (41), pp.14025-14039. ⟨10.1074/jbc.RA120.014738⟩ Article dans une revue hal-02984242v1
Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin Sylvain Gervason,Djabir Larkem,Amir Ben Mansour,Thomas Botzanowski,Christina S Mülleret al. Nature Communications, 2019, 10, pp.3566. ⟨10.1038/s41467-019-11470-9⟩ Article dans une revue hal-02276889v1
RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription Charles-Adrien Richard,Vincent Rincheval,Safa Lassoued,Jenna Fix,Christophe Cardoneet al. PLoS Pathogens, 2018, 14 (3), pp.e1006920. ⟨10.1371/journal.ppat.1006920⟩ Article dans une revue hal-01740353v1
The stress sigma factor of RNA polymerase RpoS/σ S is a solvent-exposed open molecule in solution Paola Cavaliere,Sebastien Brier,Petr Filipenko,Christina Sizun,Bertrand Raynalet al. Biochemical Journal, 2018, 475 (1), pp.341 - 354. ⟨10.1042/BCJ20170768⟩ Article dans une revue pasteur-01685123v1
New insights into structural disorder in human respiratory syncytial virus phosphoprotein and implications for binding of protein partners Nelson Pereira,Christophe Cardone,Safa Lassoued,Marie Galloux,Jenna Fixet al. Journal of Biological Chemistry, 2017, 292 (6), pp.2120-2131. ⟨10.1074/jbc.M116.765958⟩ Article dans une revue hal-01605660v1
A stretch of residues within the protease-resistant core is not necessary for prion structure and infectivity Carola Munoz-Montesino,Christina Sizun,Mohammed Moudjou,Laetitia Herzog,Fabienne Reineet al. Prion, 2017, 11 (1), pp.25-30. ⟨10.1080/19336896.2016.1274851⟩ Article dans une revue hal-01603861v1
Generating Bona Fide Mammalian Prions with Internal Deletions Carola Munoz Montesino,Christina Sizun,Mohammed Moudjou,Laetitia Herzog,Fabienne Reineet al. Journal of Virology, 2016, 90 (15), pp.6963-6975. ⟨10.1128/JVI.00555-16⟩ Article dans une revue hal-02638780v1
A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of Human Respiratory Syncytial Virus Mohamed Ouizougun-Oubari,Nelson Pereira,Bogdan Tarus,Marie Galloux,Safa Lassouedet al. Journal of Virology, 2015, 89 (21), pp.11129-11143. ⟨10.1128/JVI.01612-15⟩ Article dans une revue pasteur-02546455v1
1H, 13C and 15N resonance assignments of σS activating protein Crl from Salmonella enterica serovar Typhimurium Paola Cavaliere,Françoise Norel,Christina Sizun Biomolecular NMR Assignments, 2015, 9 (2), pp.397 - 401. ⟨10.1007/s12104-015-9617-z⟩ Article dans une revue pasteur-01413051v1
Resonance assignment of the ribosome binding domain of E. coli ribosomal protein S1. Pierre Giraud,Jean-Bernard Créchet,Marc Uzan,François Bontems,Christina Sizun Biomolecular NMR Assignments, 2015, 9 (1), pp.107-111 Article dans une revue hal-01138275v1
Binding interface between the Salmonella σ(S)/RpoS subunit of RNA polymerase and Crl: hints from bacterial species lacking crl. Paola Cavaliere,Christina Sizun,Fabienne Levi-Acobas,Mireille Nowakowski,Véronique Monteilet al. Scientific Reports, 2015, 5, pp.13564. ⟨10.1038/srep13564⟩ Article dans une revue pasteur-01392714v1
A Well-Balanced Preexisting Equilibrium Governs Electron Flux Efficiency of a Multidomain Diflavin Reductase Oriane Frances,Fataneh Fatemi,Denis Pompon,Eric Guittet,Christina Sizunet al. Biophysical Journal, 2015, 108 (6), pp.1527-1536. ⟨10.1016/j.bpj.2015.01.032⟩ Article dans une revue hal-01142871v1
Robust and low cost uniform (15)N-labeling of proteins expressed in Drosophila S2 cells and Spodoptera frugiperda Sf9 cells for NMR applications. Annalisa Meola,Célia Deville,Scott A Jeffers,Pablo Guardado-Calvo,Ieva Vasiliauskaiteet al. Journal of Structural Biology, 2014, 188 (1), pp.71-78. ⟨10.1016/j.jsb.2014.08.002⟩ Article dans une revue istex hal-01077147v1
Structure and Functional Analysis of the RNA- and Viral Phosphoprotein-Binding Domain of Respiratory Syncytial Virus M2-1 Protein. Marie-Lise Blondot,Virginie Dubosclard,Jenna Fix,Safa Lassoued,Magali Aumont-Nicaiseet al. PLoS Pathogens, 2012, 8 (5), pp.e1002734. ⟨10.1371/journal.ppat.1002734⟩ Article dans une revue hal-00722058v1
NMR structure of the human Mediator MED25 ACID domain. François Bontems,Alexis Verger,Frédérique Dewitte,Zoé Lens,Jean-Luc Baertet al. Journal of Structural Biology, 2011, 174 (1), pp.245-51. ⟨10.1016/j.jsb.2010.10.011⟩ Article dans une revue istex hal-00589014v1
1H, 13C, and 15N resonance assignment of the central domain of hRSV transcription antitermination factor M2-1. Virginie Dubosclard,Marie-Lise Blondot,Jean-François Eléouët,François Bontems,Christina Sizun Biomolecular NMR Assignments, 2011, 5 (2), pp.237-239. ⟨10.1007/s12104-011-9308-3⟩ Article dans une revue hal-00634155v1
S1 ribosomal protein functions in translation initiation and ribonuclease RegB activation are mediated by similar RNA/protein interactions. An NMR and SAXS analysis. Pascale Aliprandi,Christina Sizun,Javier Perez,Fabien Mareuil,Sandrine Caputoet al. Journal of Biological Chemistry, 2008, 283 (19), pp.13289-13301. ⟨10.1074/jbc.M707111200⟩ Article dans une revue hal-00254022v1
A simple genetic algorithm for the optimization of multidomain protein homology models driven by NMR residual dipolar coupling and small angle X-ray scattering data. Fabien Mareuil,Christina Sizun,Javier Perez,Marc Schoenauer,Jean-Yves Lallemandet al. European Biophysics Journal, 2007, 37 (1), pp.95-104. ⟨10.1007/s00249-007-0170-2⟩ Article dans une revue istex inria-00177279v2

Autre publication scientifique (3)

Interaction between RSV NS1 protein, a suppressor of antiviral immunity, and MED25 suggests a role in transcriptional regulation Christina Sizun 2023 Autre publication scientifique hal-04494604v1
Disordered, fuzzy and sticky: NMR insights into a viral scaffold protein Christina Sizun 2023 Autre publication scientifique hal-04494690v1
Biophysics for Global Health and Sustainability Christina Sizun 2023 Autre publication scientifique hal-04397650v1

Pré-publication, Document de travail (3)

Pre-assembly of biomolecular condensate seeds drives RSV replication Dhanushika Ratnayake,Marie Galloux,Sanne Boersma,Christina Sizun,Julien Sourimantet al. 2025 Pré-publication, Document de travail hal-05155891v1
Hardening of Respiratory Syncytial Virus Inclusion Bodies by Cyclopamine Proceeds through Perturbation of the Interactions between the M2-1 Protein, RNA and the P Protein Cédric Diot,Charles-Adrien Richard,Jennifer Risso-Ballester,Davy Martin,Jenna Fixet al. 2024 Pré-publication, Document de travail hal-04684081v1
Structural transitions in TCTP tumor protein upon Mcl-1 binding Florian Malard,Christina Sizun,Aurélien Thureau,Ludovic Carlier,Ewen Lescop 2022 Pré-publication, Document de travail hal-03864191v1