Christophe Arpin Scenior Immunologist

Identifiants chercheurs

IdHAL :

christophe-arpin

ORCID :

0000-0003-0915-5554

IdRef :

188564152

ResearcherID :

http://www.researcherid.com/rid/M-3862-2014

Présentation

Publications

Article dans une revue (41)

In silico modelling of CD8 T cell immune response links genetic regulation to population dynamics Thi Nhu Thao Nguyen,Madge Martin,C Arpin,Samuel Bernard,Olivier Gandrillonet al. ImmunoInformatics, 2024, 15, pp.100043. ⟨10.1016/j.immuno.2024.100043⟩ Article dans une revue hal-04489553v2
Exogenous IL-2 delays memory precursors generation and is essential for enhancing memory cells effector functions Shaoying Wang,Margaux Prieux,Simon de Bernard,Maxence Dubois,Daphne Laubretonet al. iScience, 2024, 27 (4), pp.109411. ⟨10.1016/j.isci.2024.109411⟩ Article dans une revue hal-04598215v1
In silico single-cell metabolism analysis unravels a new transition stage of CD8 T cells 4 days post-infection Christophe Arpin,Franck Picard,Olivier Gandrillon ImmunoInformatics, 2023, 14, pp.100038. ⟨10.1101/2023.09.22.558248⟩ Article dans une revue hal-04566377v1
scAN1.0: A reproducible and standardized pipeline for processing 10X single cell RNAseq data Maxime Lepetit,Mirela Diana Ilie,Marie Chanal,Gérald Raverot,Philippe Bertolinoet al. In Silico Biology, 2023, 15, pp.11 - 21. ⟨10.3233/isb-220252⟩ Article dans une revue hal-04305326v1
CD8 memory precursor cell generation is a continuous process Helena Todorov,Margaux Prieux,Daphne Laubreton,Matteo Bouvier,Shaoying Wanget al. iScience, 2022, 25 (9), pp.104927. ⟨10.1016/j.isci.2022.104927⟩ Article dans une revue hal-03842898v1
Modeling and characterization of inter-individual variability in CD8 T cell responses in mice Chloe Audebert,Daphné Laubreton,Christophe Arpin,Olivier Gandrillon,Jacqueline Marvelet al. In Silico Biology, 2021, 14 (1-2), pp.13-39. ⟨10.3233/ISB-200205⟩ Article dans une revue hal-03136073v1
Model-based assessment of the Role of Uneven Partitioning of Molecular Content on Heterogeneity and Regulation of Differentiation in CD8 T-cell Immune Responses Simon Girel,Christophe Arpin,Jacqueline Marvel,Olivier Gandrillon,Fabien Crauste Frontiers in Immunology, In press, pp.1-41. ⟨10.3389/fimmu.2019.00230⟩ Article dans une revue hal-02008705v1
Identification of Nascent Memory CD8 T Cells and Modeling of Their Ontogeny Fabien Crauste,Julien Mafille,Lilia Boucinha,Sophia Djebali,Olivier Gandrillonet al. Cell Systems, 2017, 4 (3), pp.306-317. ⟨10.1016/j.cels.2017.01.014⟩ Article dans une revue hal-01409637v1
IL-2 sensitivity and exogenous IL-2 concentration gradient tune the productive contact duration of CD8+ T cell-APC: a multiscale modeling study Xuefeng Gao,Christophe Arpin,Jacqueline Marvel,Sotiris A. Prokopiou,Olivier Gandrillonet al. BMC Systems Biology, 2016, 10 (1), pp.77. ⟨10.1186/s12918-016-0323-y⟩ Article dans une revue inserm-01354185v1
Immune signatures of protective spleen memory CD8 T cells Lilia Brinza,Sophia Djebali,Martine Tomkowiak,Julien Mafille,Céline Loiseauet al. Scientific Reports, 2016, 6, pp.37651. ⟨10.1038/srep37651⟩ Article dans une revue hal-01911427v1
Predicting pathogen-specific CD8 T cell immune responses from a modeling approach. Fabien Crauste,Emmanuelle Terry,I Le Mercier,Julien Mafille,Sophie Djebaliet al. Journal of Theoretical Biology, 2015, 374, pp.66-82. ⟨10.1016/j.jtbi.2015.03.033⟩ Article dans une revue hal-00717406v2
Multiscale Modeling of the Early CD8 T-Cell Immune Response in Lymph Nodes: An Integrative Study Sotiris Prokopiou,Loic Barbarroux,Samuel Bernard,Julien Mafille,Yann Leverrieret al. Computation, 2014, 2 (4), pp.159-181. ⟨10.3390/computation2040159⟩ Article dans une revue hal-01074736v1
Mathematical model of the primary CD8 T cell immune response: stability analysis of a nonlinear age-structured system. Emmanuelle Terry,Jacqueline Marvel,Christophe Arpin,Olivier Gandrillon,Fabien Crauste Journal of Mathematical Biology, 2012, 65, pp.263-291. ⟨10.1007/s00285-011-0459-8⟩ Article dans une revue istex hal-00649219v1
T inflammatory memory CD8 T cells participate to antiviral response and generate secondary memory cells with an advantage in XCL1 production Virginie Jubin,Erwan Ventre,Yann Leverrier,Sophia Djebali,Katia Mayolet al. Immunologic Research, 2012, 52 (3), pp.284-293. ⟨10.1007/s12026-012-8340-4⟩ Article dans une revue istex hal-02474056v1
TLR2 engagement on memory CD8 + T cells improves their cytokine-mediated proliferation and IFN-γ secretion in the absence of Ag Anne Cottalorda,Blandine C. Mercier,Florentin Mbitikon-Kobo,Christophe Arpin,Denise Teohet al. European Journal of Immunology, 2009, 39 (10), pp.2673-2681. ⟨10.1002/eji.200939627⟩ Article dans une revue hal-02474074v1
Characterization of a CD44/CD122int memory CD8 T cell subset generated under sterile inflammatory conditions. Florentin Martial Mbitikon-Kobo,Marc Vocanson,Marie-Cécile Michallet,Martine Tomkowiak,Anne Cottalordaet al. Journal of Immunology, 2009, 182 (6), pp.3846-54. ⟨10.4049/jimmunol.0802438⟩ Article dans une revue inserm-00392005v1
Nationwide survey of extended-spectrum {beta}-lactamase-producing Enterobacteriaceae in the French community setting. C. Arpin,C. Quentin,F. Grobost,E. Cambau,J. Robertet al. Journal of Antimicrobial Chemotherapy, 2009, 63 (6), pp.1205-14. ⟨10.1093/jac/dkp108⟩ Article dans une revue istex hal-00426312v1
Loss of p53 or p73 in human papillomavirus type 38 E6 and E7 transgenic mice partially restores the UV-activated cell cycle checkpoints W Dong,Christophe Arpin,R Accardi,L Gissmann,B Syllaet al. Oncogene, 2008, 27 (20), pp.2923-2928. ⟨10.1038/sj.onc.1210944⟩ Article dans une revue hal-02474213v1
Synthesis of omeprazole analogues and evaluation of these as potential inhibitors of the multidrug efflux pump NorA of Staphylococcus aureus. C; Vidaillac,J. Guillon,C. Arpin,I. Forfar-Bares,B. B. Baet al. Antimicrobial Agents and Chemotherapy, 2007, 51 (3), pp.831-8. ⟨10.1128/AAC.01306-05⟩ Article dans une revue hal-00166189v1
Extended-Spectrum {beta}-Lactamase-producing Enterobacteriaceae in Various Types of Private Health Care Centers. C. Arpin,L. Coulange,V. Dubois,C. André,I. Fischeret al. Antimicrobial Agents and Chemotherapy, 2007, Sous presse. ⟨10.1128/AAC.01431-06⟩ Article dans une revue hal-00166193v1
High genetic stability of integrons in clinical isolates of Shigella spp. of worldwide origin. V. Dubois,M. P. Parizano,C. Arpin,L. Coulange,M. C. Bezianet al. Antimicrobial Agents and Chemotherapy, 2007, 51 (4), pp.1333-40. ⟨10.1128/AAC.01109-06⟩ Article dans une revue hal-00166190v1
Differential In Vivo Persistence of Two Subsets of Memory Phenotype CD8 T Cells Defined by CD44 and CD122 Expression Levels Thierry Walzer,Christophe Arpin,Laurent Beloeil,Jacqueline Marvel Journal of Immunology, 2002, 168 (6), pp.2704-2711. ⟨10.4049/jimmunol.168.6.2704⟩ Article dans une revue hal-02474128v1
Evolution of genome size in Drosophila. is the invader`s genome being invaded by transposable elements? Cristina Vieira,C. Nardon,C. Arpin,D. Lepetit,C. Biémont Molecular Biology and Evolution, 2002, 19, pp.1154-1161 Article dans une revue hal-00427308v1
Hyperproliferative Response of a Monoclonal Memory CD8 T Cell Population Is Characterized by an Increased Frequency of Clonogenic Precursors Christophe Arpin,Georgi S. Angelov,Thierry Walzer,Martine Tomkowiak,Laurent Belœilet al. Journal of Immunology, 2002, 168 (5), pp.2147-2153. ⟨10.4049/jimmunol.168.5.2147⟩ Article dans une revue hal-02474116v1
Type II topoisomerase quinolone resistance-determining regions of Aeromonas caviae, A. hydrophila, and A. sobria complexes and mutations associated with quinolone resistance Marisol Goñi,C. Arpin,M. Capdepuy,V. Dubois,Pierre Caumetteet al. Antimicrobial Agents and Chemotherapy, 2002, 46 (2), pp.350-359. ⟨10.1128/AAC.46.2.350-359.2002⟩ Article dans une revue hal-01631903v1
Involvement of inhibitory NKRs in the survival of a subset of memory-phenotype CD8+ T cells Sophie Ugolini,Christophe Arpin,Nicolas Anfossi,Thierry Walzer,Anna Cambiaggiet al. Nature Immunology, 2001, 2 (5), pp.430-435. ⟨10.1038/87740⟩ Article dans une revue hal-02474146v1
Effects of T3R alpha 1 and T3R alpha 2 gene deletion on T and B lymphocyte development C. Arpin,M. Philgren,A. Fraichard,Denise Aubert,Jacques Samarutet al. Journal of Immunology, 2000, 164, pp.152-160 Article dans une revue hal-02685706v1
Effects of T3Rα1 and T3Rα2 Gene Deletion on T and B Lymphocyte Development Christophe Arpin,Maria Pihlgren,Alexandre Fraichard,Denise Aubert,Jacques Samarutet al. Journal of Immunology, 2000, 164 (1), pp.152-160. ⟨10.4049/jimmunol.164.1.152⟩ Article dans une revue hal-03634583v1
Characterization at the Single-Cell Level of Naive and Primed CD8 T Cell Cytokine Responses Thierry Walzer,Patrice Dubois,Martine Tomkowiak,Christophe Arpin,Maria Pihlgrenet al. Cellular Immunology, 2000, 206 (1), pp.16-25. ⟨10.1006/cimm.2000.1720⟩ Article dans une revue istex hal-02474152v1
Memory CD44int CD8 T cells show increased proliferative responses and IFN-γ production following antigenic challenge in vitro Maria Pihlgren,Christophe Arpin,Thierry Walzer,Martine Tomkowiak,Annie Thomaset al. International Immunology, 1999, 11 (5), pp.699-706. ⟨10.1093/intimm/11.5.699⟩ Article dans une revue hal-02474162v1
The Normal Counterpart of IgD Myeloma Cells in Germinal Center Displays Extensively Mutated IgVH Gene, Cμ–Cδ Switch, and λ Light Chain Expression Christophe Arpin,Odette de Bouteiller,Diane Razanajaona,Isabelle Fugier-Vivier,Francine Brièreet al. Journal of Experimental Medicine, 1998, 187 (8), pp.1169-1178. ⟨10.1084/jem.187.8.1169⟩ Article dans une revue hal-02474169v1
Dendritic Cells Enhance the Differentiation of Naive B Cells into Plasma Cells In Vitro Jérôme Fayette,Isabelle Durand,Jean-Michel Bridon,Christophe Arpin,Bertrand Duboiset al. Scandinavian Journal of Immunology, 1998, 48 (6), pp.563-570. ⟨10.1046/j.1365-3083.1998.00471.x⟩ Article dans une revue hal-02474199v1
Germinal center development Yong-Jun Liu,Christophe Arpin Immunological Reviews, 1997, 156 (1), pp.111-126. ⟨10.1111/j.1600-065x.1997.tb00963.x⟩ Article dans une revue istex hal-02474229v1
Memory B Cells Are Biased Towards Terminal Differentiation: A Strategy That May Prevent Repertoire Freezing Christophe Arpin,Jacques Banchereau,Yong-Jun Liu Journal of Experimental Medicine, 1997, 186 (6), pp.931-940. ⟨10.1084/jem.186.6.931⟩ Article dans une revue hal-02474219v1
Germinal Center Founder Cells Display Propensity for Apoptosis before Onset of Somatic Mutation Serge Lebecque,Odette de Bouteiller,Christophe Arpin,Jacques Banchereau,Yong-Jun Liu Journal of Experimental Medicine, 1997, 185 (3), pp.563-572. ⟨10.1084/jem.185.3.563⟩ Article dans une revue hal-02474258v1
Positive and Negative Selection of Human B Lymphocytes in Vitro Jacques Banchereau,Laurent Galibert,Christophe Arpin,Nicolas Burdin,Yong-Jun Liuet al. Annals of the New York Academy of Sciences, 1997, 815 (1 B-Lymphocytes), pp.237-245. ⟨10.1111/j.1749-6632.1997.tb52065.x⟩ Article dans une revue istex hal-02474241v1
Human Peripheral B Cell Development sIgM - IgD + CD38 + Hypermutated Germinal Center Centroblasts Preferentially Express Iglambda Light Chain and Have Undergone Cmu-to-Cdelta Switch Christophe Arpin,Odette de Bouteiller,Diane Razanajaona,Francine Brière,Jacques Banchereauet al. Annals of the New York Academy of Sciences, 1997, 815 (1 B-Lymphocytes), pp.193-196. ⟨10.1111/j.1749-6632.1997.tb52060.x⟩ Article dans une revue istex hal-02474251v1
Sequential triggering of apoptosis, somatic mutation and isotype switch during germinal center development Yong-Jun Liu,Christophe Arpin,Odette de Bouteiller,Christiane Guret,Jacques Banchereauet al. Seminars in Immunology, 1996, 8 (3), pp.169-177. ⟨10.1006/smim.1996.0021⟩ Article dans une revue istex hal-02474265v1
Normal Human IgD+IgM− Germinal Center B Cells Can Express Up to 80 Mutations in the Variable Region of Their IgD Transcripts Yong-Jun Liu,Odette de Bouteiller,Christophe Arpin,Francine Brière,Laurent Galibertet al. Immunity, 1996, 4 (6), pp.603-613. ⟨10.1016/s1074-7613(00)80486-0⟩ Article dans une revue hal-02474288v1
Generation of memory B cells and plasma cells in vitro Christophe Arpin,J. Dechanet,C. van Kooten,P. Merville,G. Grouardet al. Science, 1995, 268 (5211), pp.720-722. ⟨10.1126/science.7537388⟩ Article dans une revue hal-02474293v1
Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by Rapid Up-Regulation of B7-1 and B7-2 Yong-Jun Liu,Clarisse Barthélémy,Odette De Bouteiller,Christophe Arpin,Isabelle Durandet al. Immunity, 1995, 2 (3), pp.239-248. ⟨10.1016/1074-7613(95)90048-9⟩ Article dans une revue hal-02474297v1

Chapitre d'ouvrage (2)

Five Human Mature B Cell Subsets Yong-Jun Liu,Odette de Bouteiller,Christophe Arpin,Isabelle Durand,Jacques Banchereau In Vivo Immunology: Regulatory processes during lymphopoiesis and immunopoiesis, pp.289-294, 1994 Chapitre d'ouvrage hal-02238859v1
Pectinolysis regulation in Erwinia chrysanthemi Sylvie Reverchon,Nicole Hugouvieux-Cotte-Pattat,Guy Condemine,C. Bourson,Christophe Arpinet al. Plant Pathogenic Bacteria, Akademiai Kiado publishers, pp.739-744, 1990 Chapitre d'ouvrage hal-01979402v1

Pré-publication, Document de travail (1)

A temporary challenge by tumor cells can lead to a permanent partial-impairment of memory CD8 T cell function Daphné Laubreton,Margaux Prieux,Sophia Djebali,Maxence Dubois,Simon de Bernardet al. 2025 Pré-publication, Document de travail hal-04965796v1