Christos Chadjichristos

Publications

Article dans une revue (54)

Loss of NGAL protects against albumin-induced kidney inflammation and fibrosis Stefanny Figueroa,Javier Reyes Osorio,Safia Hadjadj,Gabriela Arenas,Patricio Araoset al. Renal Failure, 2026, 48 (1), ⟨10.1080/0886022X.2026.2642530⟩ Article dans une revue hal-05589000v1
From haemodynamics to kidney risk: AI-based early prediction validated in general and burn ICU populations Louis Boutin,Fedi Kadri,Arij Chaftar,Benjamin Deniau,Sakura Minaniet al. European Heart Journal - Digital Health, 2026, 7 (1), pp.ztaf150. ⟨10.1093/ehjdh/ztaf150⟩ Article dans une revue hal-05476878v1
Fibroblast‐derived neuropilin 1 alleviates renal fibrosis progression Yunzhu Shen,Sandrine Placier,Liliane Louedec,Perrine Frère,Sophie Vandermeerschet al. Journal of Pathology, 2025, Online ahead of print. ⟨10.1002/path.70009⟩ Article dans une revue hal-05440957v1
Postoperative subclinical AKI is frequent and is linked to a poor long-term prognosis in critically ill patients Louis Boutin,Christos Chadjichristos,Alexandre Mebazaa,François Dépret Indian Journal of Anaesthesia, 2025, 69 (7), pp.736-738. ⟨10.4103/ija.ija_207_25⟩ Article dans une revue hal-05172089v1
Progression of Kidney Fibrosis after Sepsis: The Underestimated Role of Resident Macrophages and Recruited Monocytes Charles de Roquetaillade,Manon Durand,Victor Beaucoté,Jérémie Guillemin,Christos Evangelos Chadjichristoset al. Journal of the American Society of Nephrology, 2025, Online ahead of print. ⟨10.1681/ASN.0000000712⟩ Article dans une revue inserm-05075620v1
Galectin-3/CD146 interaction promotes renal damage and systemic inflammation after acute kidney injury L. Boutin,S. Figueroa,E. Roger,S. Hadjadj,R. Piedagnelet al. Scientific Reports, 2025, 15 (1), pp.41575. ⟨10.1038/s41598-025-25477-4⟩ Article dans une revue hal-05390998v1
Endothelial-specific deletion of connexin 43 improves renal function and structure after acute kidney injury Magali Genest,Satoshi Kinugasa,Elena Roger,Louis Boutin,Sandrine Placieret al. Molecular Medicine, 2024, 30 (1), pp.261. ⟨10.1186/s10020-024-01011-6⟩ Article dans une revue hal-04853992v1
The role of CD146 in renal disease: from experimental nephropathy to clinics Louis Boutin,Elena Roger,Etienne Gayat,François Depret,Marcel Blot-Chabaudet al. Journal of Molecular Medicine, 2024, 102 (1), pp.113-128. ⟨10.1007/s00109-023-02392-7⟩ Article dans une revue hal-04401078v1
Subclinical and clinical acute kidney injury share similar urinary peptide signatures and prognosis Louis Boutin,Agnieszka Latosinska,Harald Mischak,Benjamin Deniau,Ayu Asakageet al. Intensive Care Medicine, 2023, 49 (10), pp.1191-1202. ⟨10.1007/s00134-023-07198-2⟩ Article dans une revue inserm-05464578v1
The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes Virgilia Sahiri,Jonathan Caron,Elena Roger,Christophe Desterke,Khalil Ghachemet al. International Journal of Molecular Sciences, 2023, 24 (3), pp.2723. ⟨10.3390/ijms24032723⟩ Article dans une revue hal-04023018v1
Galectin-3 in Kidney Diseases: From an Old Protein to a New Therapeutic Target Louis Boutin,François Dépret,Etienne Gayat,Matthieu Legrand,Christos Chadjichristos International Journal of Molecular Sciences, 2022, 23 (6), pp.3124. ⟨10.3390/ijms23063124⟩ Article dans une revue hal-03838218v1
Connexin 43: A Target for the Treatment of Inflammation in Secondary Complications of the Kidney and Eye in Diabetes Chelsy L Cliff,Bethany M Williams,Christos E Chadjichristos,Ulrik Mouritzen,Paul E Squireset al. International Journal of Molecular Sciences, 2022, 23 (2), pp.600. ⟨10.3390/ijms23020600⟩ Article dans une revue hal-03557450v1
Genetic inactivation of Semaphorin 3C protects mice from acute kidney injury Anxiang Cai,Guanyu Ye,Sandrine Placier,Perrine Frère,Brigitte Surinet al. Kidney International, 2022, 101 (4), pp.720-732. ⟨10.1016/j.kint.2021.12.028⟩ Article dans une revue inserm-03665154v1
The Role of Connexin 43 in Renal Disease: Insights from In Vivo Models of Experimental Nephropathy Elena Roger,Louis Boutin,Christos Chadjichristos International Journal of Molecular Sciences, 2022, 23 (21), pp.13090. ⟨10.3390/ijms232113090⟩ Article dans une revue hal-03891976v1
Deletion of Notch3 Impairs Contractility of Renal Resistance Vessels Due to Deficient Ca2+ Entry Frank Helle,Michael Hultström,Panagiotis Kavvadas,Bjarne Iversen,Christos E Chadjichristoset al. International Journal of Molecular Sciences, 2022, 23 (24), pp.16068. ⟨10.3390/ijms232416068⟩ Article dans une revue hal-03922921v1
Elevated plasma Galectin-3 is associated with major adverse kidney events and death after ICU admission Louis Boutin,Matthieu Legrand,Malha Sadoune,Alexandre Mebazaa,Etienne Gayatet al. Critical Care, 2022, 26 (1), pp.13. ⟨10.1186/s13054-021-03878-x⟩ Article dans une revue hal-03518948v1
Super‐resolved local recruitment of CLDN5 to filtration slits implicates a direct relationship with podocyte foot process effacement Florian Tesch,Florian Siegerist,Eleonora Hay,Nadine Artelt,Christoph Danielet al. Journal of Cellular and Molecular Medicine, 2021, 25 (16), pp.7631-7641. ⟨10.1111/jcmm.16519⟩ Article dans une revue hal-03268855v1
Endothelial-Specific Deletion of CD146 Protects Against Experimental Glomerulonephritis in Mice Ahmed Abed,Aurélie Leroyer,Panagiotis Kavvadas,Florence Authier,Richard Bachelieret al. Hypertension, 2021, 77 (4), pp.1260-1272. ⟨10.1161/HYPERTENSIONAHA.119.14176⟩ Article dans une revue hal-03226402v2
Blocking Connexin-43 mediated hemichannel activity protects against early tubular injury in experimental chronic kidney disease Gareth Price,Christos Chadjichristos,Panagiotis Kavvadas,Sydney Tang,Wai Han Yiuet al. Cell Communication and Signaling, 2020, 18 (1), pp.79. ⟨10.1186/s12964-020-00558-1⟩ Article dans une revue hal-03838304v1
Periostin Promotes Cell Proliferation and Macrophage Polarization to Drive Repair after AKI Raphaёl Kormann,Panagiotis Kavvadas,Sandrine Placier,Sophie Vandermeersch,Aude Dorisonet al. Journal of the American Society of Nephrology, 2020, 31 (1), pp.85-100. ⟨10.1681/ASN.2019020113⟩ Article dans une revue hal-02494252v1
Notch3 orchestrates epithelial and inflammatory responses to promote acute kidney injury Panagiotis Kavvadas,Zela Keuylian,Niki Prakoura,Sandrine Placier,Aude Dorisonet al. Kidney International, 2018, 94 (1), pp.126-138. ⟨10.1016/j.kint.2018.01.031⟩ Article dans une revue hal-03838330v1
The Role of Palladin in Podocytes Nadine Artelt,Tim Ludwig,Henrik Rogge,Panagiotis Kavvadas,Florian Siegeristet al. Journal of the American Society of Nephrology, 2018, 29 (6), pp.1662-1678. ⟨10.1681/ASN.2017091039⟩ Article dans une revue hal-03838331v1
Decreased Expression of Connexin 43 Blunts the Progression of Experimental GN Panagiotis Kavvadas,Ahmed Abed,Coralie Poulain,Florence Authier,Lise-Paule Labéjofet al. Journal of the American Society of Nephrology, 2017, 28 (10), pp.2915-2930. ⟨10.1681/ASN.2016111211⟩ Article dans une revue hal-03838334v1
Whole-transcriptome analysis of UUO mouse model of renal fibrosis reveals new molecular players in kidney diseases Eleni Arvaniti,Panagiotis Moulos,Athina Vakrakou,Christos Chatziantoniou,Christos Chadjichristoset al. Scientific Reports, 2016, 6 (1), pp.26235. ⟨10.1038/srep26235⟩ Article dans une revue hal-03838355v1
NF κ B-Induced Periostin Activates Integrin- β 3 Signaling to Promote Renal Injury in GN Niki Prakoura,Panagiotis Kavvadas,Raphaёl Kormann,Jean-Claude Dussaule,Christos Chadjichristoset al. Journal of the American Society of Nephrology, 2016, 28 (5), pp.1475 - 1490. ⟨10.1681/ASN.2016070709⟩ Article dans une revue hal-01528800v1
Discoidin domain receptor-1 and periostin: new players in chronic kidney disease Carlo Alfieri,Panagiotis Kavvadas,Paola Simonini,Masami Ikehata,Jean Claude Dussauleet al. Nephrology Dialysis Transplantation, 2015, 30 (12), pp.1965-1971. ⟨10.1093/ndt/gfv074⟩ Article dans une revue hal-03838393v1
Functional roles of connexins and pannexins in the kidney Ahmed Abed,Panagiotis Kavvadas,Christos Chadjichristos Cellular and Molecular Life Sciences, 2015, 72 (15), pp.2869-2877. ⟨10.1007/s00018-015-1964-5⟩ Article dans une revue hal-03838371v1
Targeting connexin 43 protects against the progression of experimental chronic kidney disease in mice Ahmed Abed,Julie Toubas,Panagiotis Kavvadas,Florence Authier,Dominique Cathelinet al. Kidney International, 2014, 86 (4), pp.768-779. ⟨10.1038/ki.2014.108⟩ Article dans une revue hal-03838395v1
Connexins in Renal Endothelial Function and Dysfunction Ahmed Abed,Jean-Claude Dussaule,Jean-Jacques Boffa,Christos Chatziantoniou,Christos Chadjichristos Cardiovascular and Hematological Disorders - Drug Targets, 2014, 14 (1), pp.15-21. ⟨10.2174/1871529x14666140401105827⟩ Article dans une revue hal-03838401v1
Progression of renal fibrosis: the underestimated role of endothelial alterations Dominique Guerrot,Jean-Claude Dussaule,Panagiotis Kavvadas,Jean-Jacques Boffa,Christos Chadjichristoset al. Fibrogenesis & Tissue Repair, 2012, 5 (Suppl 1), pp.S15 Article dans une revue inserm-00704841v1
Progression of renal fibrosis: the underestimated role of endothelial alterations Dominique Guerrot,Jean-Claude Dussaule,Panagiotis Kavvadas,Jean-Jacques Boffa,Christos Chadjichristoset al. Fibrogenesis and Tissue Repair, 2012, 5 (S1), pp.S15. ⟨10.1186/1755-1536-5-S1-S15⟩ Article dans une revue hal-03838410v1
The RenTg Mice: A Powerful Tool to Study Renin-Dependent Chronic Kidney Disease Anne-Cecile Huby,Panagiotis Kavvadas,Carlo Alfieri,Ahmed Abed,Julie Toubaset al. PLoS ONE, 2012, 7 (12), pp.e52362. ⟨10.1371/journal.pone.0052362⟩ Article dans une revue hal-03838404v1
Sox9/Sox6 and Sp1 are involved in the insulin-like growth factor-I-mediated upregulation of human type II collagen gene expression in articular chondrocytes Emmanuelle Renard,Benoît Porée,Christos Chadjichristos,Magdalini Kypriotou,Laure Maneixet al. Journal of Molecular Medicine, 2012, 90 (6), pp.649-666. ⟨10.1007/s00109-011-0842-3⟩ Article dans une revue istex hal-03838419v1
The role of cell plasticity in progression and reversal of renal fibrosis Jean-Claude Dussaule,Dominique Guerrot,Anne-Cécile Huby,Christos Chadjichristos,Nasim Shwekeet al. International Journal of Experimental Pathology, 2011, 92 (3), pp.151-157. ⟨10.1111/j.1365-2613.2011.00760.x⟩ Article dans une revue hal-03838428v1
Alteration of connexin expression is an early signal for chronic kidney disease Julie Toubas,Samantha Beck,Anne-Laure Pageaud,Anne-Cecile Huby,Mouna Mael-Aininet al. American Journal of Physiology. Renal Physiology, 2011, 301 (1), pp.F24-F32. ⟨10.1152/ajprenal.00255.2010⟩ Article dans une revue hal-03838425v1
Connexins: New genes in atherosclerosis Christos Chadjichristos,Brenda Kwak Annals of Medicine, 2009, 39 (6), pp.402-411. ⟨10.1080/07853890701436757⟩ Article dans une revue hal-03838471v1
Improvement of renal hemodynamics during hypertension-induced chronic renal disease: role of EGF receptor antagonism Frank Helle,Charlotte Jouzel,Christos Chadjichristos,Sandrine Placier,Martin Flamantet al. American Journal of Physiology. Renal Physiology, 2009, 297 (1), pp.F191-F199. ⟨10.1152/ajprenal.00015.2009⟩ Article dans une revue hal-03838442v1
Molecular role of Cx37 in advanced atherosclerosis: A micro-array study Jean-Paul Derouette,Cindy Wong,Laurent Burnier,Sandrine Morel,Esther Sutteret al. Atherosclerosis, 2009, 206 (1), pp.69-76. ⟨10.1016/j.atherosclerosis.2009.02.020⟩ Article dans une revue istex hal-03838448v1
Interleukin-1 and Transforming Growth Factor-ß 1 as Crucial Factors in Osteoarthritic Cartilage Metabolism Jean-Pierre Pujol,Christos Chadjichristos,Florence Legendre,Catherine Baugé,Gallic Beauchefet al. Connective Tissue Research, 2009, 49 (3-4), pp.293-297. ⟨10.1080/03008200802148355⟩ Article dans une revue hal-03838453v1
Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad-independent TGF-β pathway - implication of C-Krox and Sp1 Emmanuelle Renard,Christos Chadjichristos,Magdalini Kypriotou,Gallic Beauchef,Pascal Bordatet al. Journal of Cellular and Molecular Medicine, 2008, 12 (6b), pp.2836-2847. ⟨10.1111/j.1582-4934.2008.00287.x⟩ Article dans une revue hal-03838458v1
Interleukin-6 (IL-6) and/or Soluble IL-6 Receptor Down-regulation of Human Type II Collagen Gene Expression in Articular Chondrocytes Requires a Decrease of Sp1·Sp3 Ratio and of the Binding Activity of Both Factors to the COL2A1 Promoter Benoît Porée,Magdalini Kypriotou,Christos Chadjichristos,Gallic Beauchef,Emmanuelle Renardet al. Journal of Biological Chemistry, 2008, 283 (8), pp.4850-4865. ⟨10.1074/jbc.M706387200⟩ Article dans une revue hal-03838464v1
Targeting Connexin 43 Prevents Platelet-Derived Growth Factor-BB–Induced Phenotypic Change in Porcine Coronary Artery Smooth Muscle Cells Christos Chadjichristos,Sandrine Morel,Jean-Paul Derouette,Esther Sutter,Isabelle Rothet al. Circulation Research, 2008, 102 (6), pp.653-660. ⟨10.1161/CIRCRESAHA.107.170472⟩ Article dans une revue hal-03838462v1
Human Collagen Krox Up-regulates Type I Collagen Expression in Normal and Scleroderma Fibroblasts through Interaction with Sp1 and Sp3 Transcription Factors Magdalini Kypriotou,Gallic Beauchef,Christos Chadjichristos,Russell Widom,Emmanuelle Renardet al. Journal of Biological Chemistry, 2007, 282 (44), pp.32000-32014. ⟨10.1074/jbc.M705197200⟩ Article dans une revue hal-03838477v1
Role of Endogenous Fas (CD95/Apo-1) Ligand in Balloon-Induced Apoptosis, Inflammation, and Neointima Formation Christian Matter,Christos Chadjichristos,Patricia Meier,Tobias von Lukowicz,Christine Lohmannet al. Circulation, 2006, 113 (15), pp.1879-1887. ⟨10.1161/CIRCULATIONAHA.106.611731⟩ Article dans une revue hal-03838495v1
Connexin37 protects against atherosclerosis by regulating monocyte adhesion Cindy Wong,Thomas Christen,Isabelle Roth,Christos Chadjichristos,Jean-Paul Derouetteet al. Nature Medicine, 2006, 12 (8), pp.950-954. ⟨10.1038/nm1441⟩ Article dans une revue hal-03838480v1
Reduced Connexin43 Expression Limits Neointima Formation After Balloon Distension Injury in Hypercholesterolemic Mice Christos Chadjichristos,Christian Matter,Isabelle Roth,Esther Sutter,Graziano Pelliet al. Circulation, 2006, 113 (24), pp.2835-2843. ⟨10.1161/CIRCULATIONAHA.106.627703⟩ Article dans une revue hal-03838485v1
A silanized hydroxypropyl methylcellulose hydrogel for the three-dimensional culture of chondrocytes. Claire Vinatier,David Magne,Pierre Weiss,Christophe Trojani,Nathalie Rochetet al. Biomaterials, 2005, 26 (33), pp.6643-51. ⟨10.1016/j.biomaterials.2005.04.057⟩ Article dans une revue istex inserm-00110465v1
Interleukin-1 plays a major role in vascular inflammation and atherosclerosis in male apolipoprotein E-knockout mice F Merhisoussi,B Kwak,D Magne,Christos Chadjichristos,M Bertiet al. Cardiovascular Research, 2005, 66 (3), pp.583-593. ⟨10.1016/j.cardiores.2005.01.008⟩ Article dans une revue hal-03838505v1
A silanized hydroxypropyl methylcellulose hydrogel for the three-dimensional culture of chondrocytes C. Vinatier,D. Magne,P. Weiss,C. Trojani,N. Rochetet al. Biomaterials, 2005, 26 (33), pp.6643-6651. ⟨10.1016/j.biomaterials.2005.04.057⟩ Article dans une revue istex hal-03838502v1
c-Krox down-regulates the expression of UDP–glucose dehydrogenase in chondrocytes Gallic Beauchef,Magdalini Kypriotou,Christos Chadjichristos,Russell Widom,Benoît Poréeet al. Biochemical and Biophysical Research Communications, 2005, 333 (4), pp.1123-1131. ⟨10.1016/j.bbrc.2005.06.020⟩ Article dans une revue istex hal-03838499v1
SOX9 Exerts a Bifunctional Effect on Type II Collagen Gene (COL2A1) Expression in Chondrocytes Depending on the Differentiation State Magdalini Kypriotou,Magali Fossard-Demoor,Christos Chadjichristos,Chafik Ghayor,Benoit de Crombruggheet al. DNA and Cell Biology, 2003, 22 (2), pp.119-129. ⟨10.1089/104454903321515922⟩ Article dans une revue hal-03838513v1
Sp1 and Sp3 Transcription Factors Mediate Interleukin-1β Down-regulation of Human Type II Collagen Gene Expression in Articular Chondrocytes Christos Chadjichristos,Chafik Ghayor,Magdalini Kypriotou,Grégoire Martin,Renard Emmanuelleet al. Journal of Biological Chemistry, 2003, 278 (41), pp.39762-39772. ⟨10.1074/jbc.M303541200⟩ Article dans une revue hal-03838509v1
Down-regulation of Human Type II Collagen Gene Expression by Transforming Growth Factor-β1 (TGF-β1) in Articular Chondrocytes Involves SP3/SP1 Ratio Christos Chadjichristos,Chafik Ghayor,Jean-François Herrouin,Leena Ala-Kokko,Gunthram Suskeet al. Journal of Biological Chemistry, 2002, 277 (46), pp.43903-43917. ⟨10.1074/jbc.M206111200⟩ Article dans une revue hal-03838515v1
SP3 Represses the SP1-mediated Transactivation of the HumanCOL2A1 Gene in Primary and De-differentiated Chondrocytes Chafik Ghayor,Christos Chadjichristos,Jean-François Herrouin,Leena Ala-Kokko,Guntram Suskeet al. Journal of Biological Chemistry, 2001, 276 (40), pp.36881-36895. ⟨10.1074/jbc.M105083200⟩ Article dans une revue hal-03838523v1

Chapitre d'ouvrage (1)

Connexins in Atherosclerosis Christos Chadjichristos,Jean-Paul Derouette,Brenda Kwak Cardiovascular Gap Junctions, 42, KARGER, pp.255-267, 2006, ⟨10.1159/000092574⟩ Chapitre d'ouvrage hal-03838488v1