Claire BERTRAND Associate Professor

Identifiants chercheurs

IdHAL :

claire-bertrand

ORCID :

0000-0001-5595-0677

IdRef :

070197970

Présentation

I am an Associate Professor at the University of Lorraine, where I have been working at the DynAMic laboratory since 2010. After postdoctoral training at the University of Lorraine and at Durham University (UK), I developed expertise in bacterial genetics and molecular biology. My research focuses on the molecular mechanisms underlying genetic plasticity in Streptomyces, soil bacteria with a remarkable capacity for environmental adaptation. In particular, I investigate DNA double-strand break repair pathways (NHEJ and homologous recombination), the role of the endonuclease NucS in gene fluxes, and the relationship between chromatin organization and chromosome compartmentalization. I teach genetics, molecular microbiology, and biotechnology, and I am actively involved in academic and educational responsibilities within the BioMIM curriculum and the Master’s program in Microbiology.

Publications

Article dans une revue (10)

Correction of non-random mutational biases along a linear bacterial chromosome by the mismatch repair endonuclease NucS Oyut Dagva,Annabelle Thibessard,Jean-Noël Lorenzi,Victor Labat,Emilie Piotrowskiet al. Nucleic Acids Research, 2024, 52 (9), pp.5033-5047. ⟨10.1093/nar/gkae132⟩ Article dans une revue hal-04495979v1
Bacterial NHEJ: A never ending story Claire Bertrand,Annabelle Thibessard,Claude Bruand,François Lecointe,Pierre Leblond Molecular Microbiology, 2019, 11, pp.1139-1151. ⟨10.1111/mmi.14218⟩ Article dans une revue hal-02044826v1
Draft Whole-Genome Shotgun Sequence of Streptomyces sp. Strain ETH9427 Annabelle Thibessard,Cláudia M Vicente,Claire Bertrand,Bertrand Aigle,Pierre Leblond Microbiology Resource Announcements, 2018, 7 (12), pp.e01197. ⟨10.1128/MRA.01197-18⟩ Article dans une revue hal-01887322v1
Genome plasticity is governed by double strand break DNA repair in Streptomyces Grégory Hoff,Claire Bertrand,Emilie Piotrowski,Annabelle Thibessard,Pierre Leblond Scientific Reports, 2018, 8 (1), pp.5272. ⟨10.1038/s41598-018-23622-w⟩ Article dans une revue hal-01757262v1
Implication of RuvABC and RecG in homologous recombination in Streptomyces ambofaciens Gregory Hoff,Claire Bertrand,Emilie Piotrowski,Annabelle Thibessard,Pierre Leblond Research in Microbiology, 2017, 168 (1), pp.26-35. ⟨10.1016/j.resmic.2016.07.003⟩ Article dans une revue hal-01552147v1
Multiple and Variable NHEJ-Like Genes Are Involved in Resistance to DNA Damage in Streptomyces ambofaciens Grégory Hoff,Claire Bertrand,Lingli Zhang,Emilie Piotrowski,Ludovic Chipotet al. Frontiers in Microbiology, 2016, 7, pp.1901. ⟨10.3389/fmicb.2016.01901⟩ Article dans une revue hal-01521993v1
Construction of pDYN6902, a new Streptomyces integrative expression vector designed for cloning sequences interfering with Escherichia coli viability Annabelle Thibessard,Claire Bertrand,Julien Hiblot,Emilie Piotrowski,Pierre Leblond Plasmid, 2015, 82, pp.43-49. ⟨10.1016/j.plasmid.2015.10.003⟩ Article dans une revue hal-01258339v1
The adnAB Locus, Encoding a Putative Helicase-Nuclease Activity, Is Essential in Streptomyces L. Zhang,Cong Tu Nguyen,L. Chipot,E. Piotrowski,C. Bertrandet al. Journal of Bacteriology, 2014, 196 (14), pp.2701 - 2708. ⟨10.1128/JB.01513-14⟩ Article dans une revue hal-01474715v1
Arabidopsis HAF2 gene encoding TATA-binding protein (TBP)-associated factor TAF1, is required to integrate light signals to regulate gene expression and growth Claire Bertrand,Moussa Benhamed,You-Fang Li,Mira Ayadi,Gaetan G. Lemonnieret al. Journal of Biological Chemistry, 2005, 280 (2), pp.1465-1473. ⟨10.1074/jbc.M409000200⟩ Article dans une revue hal-02675476v1
Arabidopsis Histone Acetyltransferase AtGCN5 Regulates the Floral Meristem Activity through the WUSCHEL/AGAMOUS Pathway Claire Bertrand,Catherine Bergounioux,Séverine Domenichini,Marianne Delarue,Dao-Xiu Zhou Journal of Biological Chemistry, 2003, 278 (30), pp.28246 - 28251. ⟨10.1074/jbc.m302787200⟩ Article dans une revue hal-05242274v1

Communication dans un congrès (3)

Double strand break repair triggers genome plasticity in Streptomyces Grégory Hoff,Claire Bertrand,Emilie Piotrowski,Annabelle Thibessard,Pierre Leblond Actino2017 Journées des Actinobactéries, Oct 2017, Lyon, France Communication dans un congrès hal-01655543v1
Double strand break repair triggers genome plasticity in Streptomyces Grégory Hoff,Claire Bertrand,Emilie Piotrowski,Annabelle Thibessard,Pierre Leblond Prokagenomics 2017 7th European Conference on Prokaryotic and Fungal Genomics, Sep 2017, Göttingen, Germany Communication dans un congrès hal-01655261v1
Double strand break repair triggers genome plasticity in Streptomyces Grégory Hoff,Claire Bertrand,Emilie Piotrowski,Stephen T Mcgovern,François Lecointeet al. International Symposium on the Biology of Actinomycetes, May 2017, Jeju, South Korea Communication dans un congrès hal-01655226v1

Ouvrages (1)

DNA repair | Nonhomologous End-Joining in Bacteria Annabelle Thibessard,Claire Bertrand,Edward Bartlett,Aidan Doherty,Claude Bruandet al. Elsevier, pp.289-295, 2021, ⟨10.1016/B978-0-12-819460-7.00150-X⟩ Ouvrages hal-05046362v1

Chapitre d'ouvrage (1)

Nonhomologous End-Joining in Bacteria Annabelle Thibessard,Claire Bertrand,Edward J Bartlett,Aidan J Doherty,Claude Bruandet al. Joseph Jez. Encyclopedia of Biological Chemistry 3rd Edition,, 4, Elsevier, 2021, 9780128194607 Chapitre d'ouvrage hal-03319644v1