Claire Wyart

48
Documents

Présentation

Date of birth:

Feb. 16, 1977

Position:

Group leader in the Paris Brain Institute (ICM)

INSERM Director of Research

Citizenships: France & USA

Dependents: 3 children

Education

Institution

Diploma

Years

Major

Ecole Normale Supérieure Ulm, Paris

Bachelor

Master

1996-2000

Biology

Neurosciences

Institute of Physics, Strasbourg

PhD

2000-2003

Neurosciences & Biophysics

Address Institut du Cerveau (ICM), INSERM U1127, 47 bld hopital, 75013 Paris, France

Email: claire.wyart@icm-institute.org Phone: +33 157 274 310

Websites

Lab https://wyartlab.org ~ https://zenith-etn.com ~ Outreach https://adioscorona.org

Positions

2017 Promotion to Inserm Research Director (DR2)

2011 Group Leader ATIP-Avenir, Institut du Cerveau (ICM), France

2011 Inserm Researcher Position through national competitive selection (CR1)

2009-10 Life Science Research Associate, Mol. & Cell. Biology, UC Berkeley, USA

2005-09 Postdoctoral Fellow, Molecular and Cellular Biology dept, UC Berkeley, USA

Prizes

2019 Elected EMBO member

Grand Prix of Mrs. Victor Noury from the French National Academy

2017 EMBO-Young Investigator Program (EMBO-YIP) Award

Foundation Science Education Research (FSER) First Prize of the jury

2016 New York Stem Cell Foundation Robertson Innovator Neuroscience Award

2013 Irène Joliot-Curie Prize for women in science

2011 Prize Atip-Avenir of the Bettencourt-Schueller Foundation (FBS)

Emergence Prize from the City of Paris

2010 Chair of Excellence of School of Neurosciences of Paris (ENP)

2005 Prize of the Foundation Blancmesnil for the documentary TERMA

2004 Best PhD from Louis Pasteur University

Coordination of research programs

2020 European Research Council (ERC) - Consolidator grant

Fondation Recherche Médicale (FRM) Team label

2018 European Research Council - Proof of Concept Grant

Human Frontier Research Program (HFSP) coordinator

2016 New York Stem Cell Foundation (NYSCF) award

2013 Human Frontier Research Program (HFSP) coordinator

2012 European Research Council - Starting Grant

Scientific board & committees

2020-23 Fondation Recherche Médicale (FRM)

2018-21 FENS-Kavli Network of Excellence board member

2017-20 Fondation Cotrel

2016-21 FENS-Kavli Network of Excellence scholar

2016 CNRS Selection committee for researchers in neurosciences (CNRS#25)

Member of editorial committee

Current Biology (2017-now), eLife (2018-now), Current Opinion in Physiology (2018-19).

Publications and conferences

∞ 60 publications in journals including Nature (1), Science (2), Nature Methods (1), eLife (4), Neuron (1), Nature Communications (3), Nature Neuroscience (1), Current Biology (6).

∞ > 50 invitations to present at international conferences since 2016.

∞ > 20 invitations to give a seminar in an institute since 2016.

Researcher ID

ORCID: 0000-0002-1668-4975 & Web Of Science: AAB-4603-2020

Publications

Publications

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Uncovering multiscale structure in the variability of larval zebrafish navigation

Gautam Sridhar , Massimo Vergassola , João C Marques , Michael B Orger , Antonio Carlos Costa et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (47), pp.e2410254121. ⟨10.1073/pnas.2410254121⟩
Article dans une revue hal-04729187 v2
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Fluctuating Landscapes and Heavy Tails in Animal Behavior

Antonio Carlos Costa , Gautam Sridhar , Claire Wyart , Massimo Vergassola
Article dans une revue hal-04729188 v1
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CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection

Andrew Prendergast , Kin Ki Jim , Hugo Marnas , Laura Desban , Feng Quan et al.
Current Biology, 2023, 33 (5), pp.940-956.e10. ⟨10.1016/j.cub.2023.01.039⟩
Article dans une revue hal-04032555 v1
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SCO-spondin knockout mice exhibit small brain ventricles and mild spine deformation

Huixin Xu , Guillaume P Dugué , Yasmine Cantaut-Belarif , François-Xavier Lejeune , Suhasini Gupta et al.
Fluids and Barriers of the CNS, 2023, 20 (1), pp.89. ⟨10.1186/s12987-023-00491-8⟩
Article dans une revue hal-04336908 v2
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Cerebrospinal fluid-contacting neurons: multimodal cells with diverse roles in the CNS

Claire Wyart , Martin Carbo-Tano , Yasmine Cantaut-Belarif , Adeline Orts-Del’immagine , Urs L Böhm
Nature Reviews Neuroscience, 2023, 24 (9), pp.540-556. ⟨10.1038/s41583-023-00723-8⟩
Article dans une revue hal-04192775 v1
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The Reissner fiber under tension in vivo shows dynamic interaction with ciliated cells contacting the cerebrospinal fluid

Celine Bellegarda , Guillaume Zavard , Lionel Moisan , Françoise Brochard-Wyart , Jean-François Joanny et al.
eLife, 2023, 12, ⟨10.7554/eLife.86175⟩
Article dans une revue hal-04302096 v1
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[Polymodal sensory integration at the interface with the cerebrospinal fluid].

Claire Wyart
Médecine/Sciences, 2023, 39 (6-7), pp.537-543. ⟨10.1051/medsci/2023082⟩
Article dans une revue hal-04505931 v1
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Granger causality analysis for calcium transients in neuronal networks, challenges and improvements

Xiaowen Chen , Faustine Ginoux , Martin Carbo-Tano , Thierry Mora , Aleksandra Walczak et al.
eLife, 2023, 12, pp.e81279. ⟨10.7554/eLife.81279⟩
Article dans une revue hal-04252210 v1
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Loss of CSF-contacting neuron sensory function is associated with a hyper-kyphosis of the spine reminiscent of Scheuermann’s disease

Laura Marie-Hardy , Lotfi Slimani , Giulia Messa , Zaineb El Bourakkadi , Annick Prigent et al.
Scientific Reports, 2023, 13 (5529), ⟨10.1038/s41598-023-32536-1⟩
Article dans une revue (data paper) hal-04064556 v1
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The mesencephalic locomotor region recruits V2a reticulospinal neurons to drive forward locomotion in larval zebrafish

Martin Carbo-Tano , Mathilde Lapoix , Xinyu Jia , Olivier Thouvenin , Marco Pascucci et al.
Nature Neuroscience, 2023, 26 (10), pp.1775-1790. ⟨10.1038/s41593-023-01418-0⟩
Article dans une revue hal-04362291 v1
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Evolutionary divergence of locomotion in two related vertebrate species

Gokul Rajan , Julie Lafaye , Martin Carbo-Tano , Karine Duroure , Giulia Faini et al.
Cell Reports, 2022, 38 (13), pp.110585. ⟨10.1016/j.celrep.2022.110585⟩
Article dans une revue hal-03142570 v2
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A lexical approach for identifying behavioural action sequences

Gautam Reddy , Laura Desban , Hidenori Tanaka , Julian Roussel , Olivier Mirat et al.
PLoS Computational Biology, 2022, 18 (1), pp.e1009672. ⟨10.1371/journal.pcbi.1009672⟩
Article dans une revue hal-03521462 v1
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Automated Analysis of Cerebrospinal Fluid Flow and Motile Cilia Properties in The Central Canal of Zebrafish Embryos

Olivier Thouvenin , Yasmine Cantaut-Belarif , Ludovic Keiser , Francois Gallaire , Claire Wyart
Bio-protocol , 2021, 11 (5), ⟨10.21769/BioProtoc.3932⟩
Article dans une revue hal-03191555 v1
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Spinal sensory neurons project onto hindbrain to stabilize posture and enhance locomotor speed

Ming-Yue Wu , Martin Carbó-Tano , Olivier Mirat , Francois-Xavier Lejeune , Julian Roussel et al.
Current Biology, 2021, ⟨10.1016/j.cub.2021.05.042⟩
Article dans une revue hal-03334718 v1
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Sensory neurons contacting the cerebrospinal fluid require the Reissner fiber to detect spinal curvature in vivo

Adeline Orts-Del'Immagine , Yasmine Cantaut-Belarif , Olivier Thouvenin , Julian Roussel , Asha Baskaran et al.
Current Biology, 2020
Article dans une revue hal-03334720 v1
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Origin and role of the cerebrospinal fluid bidirectional flow in the central canal

Olivier Thouvenin , Ludovic Keiser , Yasmine Cantaut-Belarif , Martin Carbo-Tano , Frederik J. Verweij et al.
eLife, 2020, 9, pp.e47699. ⟨10.7554/eLife.47699⟩
Article dans une revue hal-02489664 v1
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Somatostatin 1.1 contributes to the innate exploration of zebrafish larva

Feng B Quan , Laura Desban , Olivier Mirat , Maxime Kermarquer , Julian Roussel et al.
Scientific Reports, 2020, 10, pp.15235. ⟨10.1038/s41598-020-72039-x⟩
Article dans une revue mnhn-02943951 v1
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Experience, circuit dynamics, and forebrain recruitment in larval zebrafish prey capture

Claire S Oldfield , Irene Grossrubatscher , Mario Chavez , Adam Hoagland , Alex R Huth et al.
eLife, 2020, 9, pp.e56619. ⟨10.7554/eLife.56619⟩
Article dans une revue hal-03019795 v1
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Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface

Frederick B Shipley , Neil Dani , Huixin Xu , Christopher Deister , Jin Cui et al.
Neuron, 2020, 108 (4), pp.623-639.e10. ⟨10.1016/j.neuron.2020.08.024⟩
Article dans une revue hal-04539366 v1
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A calibrated optogenetic toolbox of stable zebrafish opsin lines

Paride Antinucci , Adna Dumitrescu , Charlotte Deleuze , Holly Morley , Kristie Leung et al.
Article dans une revue hal-02540191 v1
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Adrenergic activation modulates the signal from the Reissner fiber to cerebrospinal fluid-contacting neurons during development

Yasmine Cantaut-Belarif , Adeline Orts Del'Immagine , Margot Penru , Guillaume Pézeron , Claire Wyart et al.
Article dans une revue hal-02975594 v1
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Regulation of the apical extension morphogenesis tunes the mechanosensory response of microvilliated neurons

Laura Desban , Andrew Prendergast , Julian Roussel , Marion Rosello , David Geny et al.
PLoS Biology, 2019, 17 (4), pp.e3000235. ⟨10.1371/journal.pbio.3000235⟩
Article dans une revue hal-02136729 v1
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Dynactin1 depletion leads to neuromuscular synapse instability and functional abnormalities

Valerie Bercier , Jeffrey Hubbard , Kevin Fidelin , Karine Duroure , Thomas O Auer et al.
Molecular Neurodegeneration, 2019, 14 (1), pp.27. ⟨10.1186/s13024-019-0327-3⟩
Article dans une revue hal-02273092 v1
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Title Taking a big step towards understanding locomotion Authors list

Claire Wyart
Trends in Neurosciences, 2018, 41 (12), pp.869-870
Article dans une revue hal-01971726 v1
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Investigation of hindbrain activity during active locomotion reveals inhibitory neurons involved in sensorimotor processing

Kristen E Severi , Urs L Böhm , Claire Wyart
Scientific Reports, 2018, 8 (1), pp.13615. ⟨10.1038/s41598-018-31968-4⟩
Article dans une revue hal-04403445 v1
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Multiplexed temporally focused light shaping for high-resolution multi-cell targeting

Nicolò Accanto , Clément Molinier , Dimitrii Tanese , Emiliano Ronzitti , Zachary L. Newman et al.
Optica, 2018, 5 (11), pp.1478-1491
Article dans une revue hal-01945948 v1
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Pkd2l1 is required for mechanoception in cerebrospinal fluid-contacting neurons and maintenance of spine curvature

Jenna Sternberg , Andrew Prendergast , Lucie Brosse , Yasmine Cantaut-Belarif , Olivier Thouvenin et al.
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-06225-x⟩
Article dans une revue hal-01918990 v1

The Reissner Fiber in the Cerebrospinal Fluid Controls Morphogenesis of the Body Axis

Yasmine Cantaut-Belarif , Jenna Sternberg , Olivier Thouvenin , Claire Wyart , Pierre-Luc Bardet
Current Biology, 2018, 28 (15), pp.2479-2486.e4. ⟨10.1016/j.cub.2018.05.079⟩
Article dans une revue hal-04032491 v1
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Multiplexed temporally focused light shaping for high-resolution multi-cell targeting

Nicolò Accanto , Clément Molinier , Dimitrii Tanese , Emiliano Ronzitti , Zachary L Newman et al.
Optica, 2018, 5 (11), pp.1478. ⟨10.1364/OPTICA.5.001478⟩
Article dans une revue hal-04413986 v1
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The dual developmental origin of spinal cerebrospinal fluid-contacting neurons gives rise to distinct functional subtypes

Lydia Djenoune , Laura Desban , Johanna Gomez , Jenna R. Sternberg , Andrew Prendergast et al.
Scientific Reports, 2017, 7 (1), pp.719. ⟨10.1038/s41598-017-00350-1⟩
Article dans une revue hal-01516797 v1
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Mechanosensory neurons control the timing of spinal microcircuit selection during locomotion

Steven Knafo , Kevin Fidelin , Andrew Prendergast , Po-En Brian Tseng , Alexandre Parrin et al.
eLife, 2017, 2017 (6), pp.e25260. ⟨10.7554/eLife.25260⟩
Article dans une revue hal-01954973 v1
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Intraspinal Sensory Neurons Provide Powerful Inhibition to Motor Circuits Ensuring Postural Control during Locomotion

Jeffrey michael Hubbard , Urs lucas Böhm , Andrew Prendergast , Po-En brian Tseng , Morgan Newman et al.
Current Biology, 2016, ⟨10.1016/j.cub.2016.08.026⟩
Article dans une revue hal-01382762 v1
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Three-dimensional spatiotemporal focusing of holographic patterns

Oscar Hernandez , Eirini Papagiakoumou , Dimitrii Tanese , Kevin Fidelin , Claire Wyart et al.
Nature Communications, 2016, 7 (1), ⟨10.1038/ncomms11928⟩
Article dans une revue hal-01963770 v1
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Remote z-scanning with a macroscopic voice coil motor for fast 3D multiphoton laser scanning microscopy

Peter Rupprecht , Andrew Prendergast , Claire Wyart , Rainer W. Friedrich
Biomedical optics express, 2016, 7 (5), pp.1656-1671. ⟨10.1364/BOE.7.001656⟩
Article dans une revue hal-01327206 v1
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CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits

Urs Lucas Böhm , Andrew Prendergast , Lydia Djenoune , Sophie Nunes Figueiredo , Johanna Gomez et al.
Nature Communications, 2016, 7, pp.10866 ⟨10.1038/ncomms10866⟩
Article dans une revue hal-01285569 v1
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Spinal sensory circuits in motion

Urs Lucas Böhm , Claire Wyart
Current Opinion in Neurobiology, 2016, 41, pp.38-43. ⟨10.1016/j.conb.2016.07.007⟩
Article dans une revue hal-01371943 v1
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Comparative Distribution and In Vitro Activities of the Urotensin II-Related Peptides URP1 and URP2 in Zebrafish: Evidence for Their Colocalization in Spinal Cerebrospinal Fluid-Contacting Neurons

Feng B. Quan , Christophe Dubessy , Sonya Galant , Natalia B. Kenigfest , Lydia Djenoune et al.
PLoS ONE, 2015, 10 (3), pp.e0119290. ⟨10.1371/journal.pone.0119290⟩
Article dans une revue hal-01227829 v1
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State-Dependent Modulation of Locomotion by GABAergic Spinal Sensory Neurons

Kevin Fidelin , Lydia Djenoune , Caleb Stokes , Andrew Prendergast , Johanna Gómez et al.
Current Biology, 2015, 25 (23), pp.3035-3047. ⟨10.1016/j.cub.2015.09.070⟩
Article dans une revue hal-01941112 v1
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Deletion of a kinesin I motor unmasks a mechanism of homeostatic branching control by neurotrophin-3

Thomas O. Auer , Tong Xiao , Valerie Bercier , Christoph Gebhardt , Karine Duroure et al.
eLife, 2015, 4, pp.e05061. ⟨10.7554/eLife.05061.030⟩
Article dans une revue hal-01214787 v1
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Fast Calcium Imaging with Optical Sectioning via HiLo Microscopy

Marcel A. Lauterbach , Emiliano Ronzitti , Jenna R. Sternberg , Claire Wyart , Valentina Emiliani
PLoS ONE, 2015, 10 (12), pp.e0143681. ⟨10.1371/journal.pone.0143681⟩
Article dans une revue hal-01272977 v1
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Investigation of spinal cerebrospinal fluid-contacting neurons expressing PKD2L1: evidence for a conserved system from fish to primates

Lydia Djenoune , Hanen Khabou , Fanny Joubert , Feng B. Quan , Sophie Nunes Figueiredo et al.
Frontiers in Neuroanatomy, 2014, 8, pp.26. ⟨10.3389/fnana.2014.00026⟩
Article dans une revue hal-01321299 v1
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Endothelial Cilia Mediate Low Flow Sensing during Zebrafish Vascular Development

Jacky G. Goetz , Emily Steed , Rita R. Ferreira , Stéphane Roth , Caroline Ramspacher et al.
Cell Reports, 2014, 6 (5), pp.799-808. ⟨10.1016/j.celrep.2014.01.032⟩
Article dans une revue hal-01311698 v1
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Hierarchy of Neural Organization in the Embryonic Spinal Cord: Granger-Causality Graph Analysis of Calcium Imaging Data

Fabrizio de Vico Fallani , Martina Corazzol , Jenna Sternberg , Claire Wyart , Mario Chavez
IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2014, pp.10. ⟨10.1109/TNSRE.2014.2341632⟩
Article dans une revue hal-01112731 v1

Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway

Elim Hong , Kirankumar Santhakumar , Courtney A. Akitake , Sang Jung Ahn , Christine Thisse et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (52), pp.21171-21176. ⟨10.1073/pnas.1319566110⟩
Article dans une revue hal-01542736 v1
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ZebraZoom: an automated program for high-throughput behavioral analysis and categorization

Olivier Mirat , Jenna R. Sternberg , Kristen E. Severi , Claire Wyart
Frontiers in Neural Circuits, 2013, 7, pp.107. ⟨10.3389/fncir.2013.00107⟩
Article dans une revue hal-01578454 v1

Dynamics of excitatory synaptic components in sustained firing at low rates.

Claire Wyart , Simona Cocco , Laurent Bourdieu , Jean-Francois Léger , Catherine Herr et al.
Journal of Neurophysiology, 2005, 93 (6), pp.3370-80. ⟨10.1152/jn.00530.2004⟩
Article dans une revue hal-00145309 v1

Constrained synaptic connectivity in functional mammalian neuronal networks grown on patterned surfaces.

Claire Wyart , Christophe Ybert , Laurent Bourdieu , Catherine Herr , Christelle Prinz et al.
Journal of Neuroscience Methods, 2002, 117 (2), pp.123-31
Article dans une revue hal-00145442 v1