|
Replication-poison treatment in BRCA1-deficient breast cancer causes MRE11 over-resection that induces single-stranded DNA accumulation and Mitotic Catastrophe
Imene Tabet
,
Esin Orhan
,
Ermes Candiello
,
Lise Fenou
,
Carolina Velázquez
et al.
Article dans une revue
(data paper)
hal-04931535
v1
|
|
CDK inhibition results in pharmacologic BRCAness increasing sensitivity to olaparib in BRCA1-WT and olaparib resistant in Triple Negative Breast Cancer
Esin Orhan
,
Carolina Velazquez
,
Imene Tabet
,
Lise Fenou
,
Geneviève Rodier
et al.
Article dans une revue
hal-04535765
v1
|
|
BRCA1-methylated triple negative breast cancers previously exposed to neoadjuvant chemotherapy form RAD51 foci and respond poorly to olaparib
Carolina Velazquez
,
Esin Orhan
,
Imene Tabet
,
Lise Fenou
,
Béatrice Orsetti
et al.
Article dans une revue
hal-04275543
v1
|
|
In high grade ovarian carcinoma, platinum-sensitive tumor recurrence and acquired-resistance derive from quiescent residual cancer cells that overexpress CRYAB, CEACAM6 and SOX2
Stanislas Du Manoir
,
Hélène Delpech
,
Béatrice Orsetti
,
William Jacot
,
Nelly Pirot
et al.
Article dans une revue
inserm-03613881
v1
|
|
RNF219 regulates CCR4-NOT function in mRNA translation and deadenylation
Aude Guénolé
,
Fabien Velilla
,
Aymeric Chartier
,
April Rich
,
Anne-Ruxandra Carvunis
et al.
Article dans une revue
hal-04275608
v1
|
|
Multi-Level Control of the ATM/ATR-CHK1 Axis by the Transcription Factor E4F1 in Triple-Negative Breast Cancer
Kalil Batnini
,
Thibault Houles
,
Olivier Kirsh
,
Stanislas Du Manoir
,
Mehdi Zaroual
et al.
Article dans une revue
hal-03845417
v1
|
|
Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition
Simon Hayek
,
Nicolas Pietrancosta
,
Anna Hovhannisyan
,
Rodolphe Alves de Sousa
,
Nassima Bekaddour
et al.
Article dans une revue
hal-02372490
v1
|
|
Distinct oncogenes drive different genome and epigenome alterations in human mammary epithelial cells
Claire Fonti
,
Anne Saumet
,
Amanda Abi-Khalil
,
Béatrice Orsetti
,
Elouan Cleroux
et al.
Article dans une revue
inserm-02177754
v1
|
|
Coprs inactivation leads to a derepression of LINE1 transposons in spermatocytes
Conception Paul
,
Hélène Delpech
,
Delphine Haouzi
,
Samir Hamamah
,
Claude Sardet
et al.
Article dans une revue
hal-02414875
v1
|
|
Cell-cycle regulation of non-enzymatic functions of the Drosophila methyltransferase PR-Set7
Amel Zouaz
,
Céline Fernando
,
Yannick Perez
,
Claude Sardet
,
Eric Julien
et al.
Article dans une revue
hal-02292938
v1
|
|
Histone H4K20 tri‐methylation at late‐firing origins ensures timely heterochromatin replication
Julien Brustel
,
Nina Kirstein
,
Fanny Izard
,
Charlotte Grimaud
,
Paulina Prorok
et al.
Article dans une revue
hal-02154100
v1
|
|
Checkpoint kinase 1 inhibition sensitises transformed cells to dihydroorotate dehydrogenase inhibition
Stéphanie Arnould
,
Genevieve Rodier
,
Gisèle Matar
,
Charles Vincent
,
Nelly Pirot
et al.
Article dans une revue
hal-02291385
v1
|
|
Checkpoint kinase 1 inhibition sensitises transformed cells to dihydroorotate dehydrogenase inhibition
Stéphanie Arnould
,
Geneviève Rodier
,
Gisèle Matar
,
Charles Vincent
,
Nelly Pirot
et al.
Article dans une revue
hal-04766813
v1
|
|
E4F1 controls a transcriptional program essential for pyruvate dehydrogenase activity
Matthieu Lacroix
,
Geneviève Rodier
,
Olivier Kirsh
,
Thibault Houles
,
Hélène Delpech
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (39), pp.10998-11003. ⟨10.1073/pnas.1602754113⟩
Article dans une revue
hal-01837650
v1
|
|
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis
Perrine Goguet-Rubio
,
Berfin Seyran
,
Laurie Gayte
,
Florence F. Bernex
,
Anne Sutter
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (39), pp.11004-11009. ⟨10.1073/pnas.1602751113⟩
Article dans une revue
inserm-02465232
v1
|
|
Description of an optimized ChIP-seq analysis pipeline dedicated to genome wide identification of E4F1 binding sites in primary and transformed MEFs
Thibault Houlès
,
Geneviève Rodier
,
Laurent Le Cam
,
Claude Sardet
,
Olivier Kirsh
Article dans une revue
hal-04766820
v1
|
|
The Transcription Factor E4F1 Coordinates CHK1-Dependent Checkpoint and Mitochondrial Functions
Geneviève Rodier
,
Olivier Kirsh
,
Martín Baraibar
,
Thibault Houlès
,
Matthieu Lacroix
et al.
Article dans une revue
hal-01213872
v1
|
|
The Wnt-target gene Dlk-1 is regulated by the Prmt5-associated factor Copr5 during adipogenic conversion
Conception Paul
,
Claude Sardet
,
Eric Fabbrizio
Article dans une revue
hal-02277973
v1
|
|
The Transcription Factor E4F1 Coordinates CHK1-Dependent Checkpoint and Mitochondrial Functions
Geneviève Rodier
,
Olivier Kirsh
,
Martín Baraibar
,
Thibault Houlès
,
Matthieu Lacroix
et al.
Article dans une revue
hal-04766824
v1
|
|
Description of an optimized ChIP-seq analysis pipeline dedicated to genome wide identification of E4F1 binding sites in primary and transformed MEFs
Thibault Houles
,
Geneviève Rodier
,
Laurent Le Cam
,
Claude Sardet
,
Olivier Kirsh
Article dans une revue
hal-02317536
v1
|
|
E4F1 dysfunction results in autophagic cell death in myeloid leukemic cells
Elodie Hatchi
,
Geneviève Rodier
,
Claude Sardet
,
Laurent Le Cam
Article dans une revue
hal-04766830
v1
|
|
PRMT5-mediated histone H4 arginine-3 symmetrical dimethylation marks chromatin at G + C-rich regions of the mouse genome
Michael Girardot
,
Ryutaro Hirasawa
,
Salim Kacem
,
Lauriane Fritsch
,
Julien Pontis
et al.
Article dans une revue
hal-03051652
v1
|
|
Leukoencephalopathy with cysts and hyperglycinemia may result from NFU1 deficiency
M. Nizon
,
A. Boutron
,
N. Boddaert
,
A. Slama
,
Hélène Delpech
et al.
Article dans une revue
hal-02181366
v1
|
|
PRMT5-mediated histone H4 arginine-3 symmetrical dimethylation marks chromatin at G + C-rich regions of the mouse genome
Michael Girardot
,
Ryutaro Hirasawa
,
Salim Kacem
,
L. Fritsch
,
J. Pontis
et al.
Article dans une revue
hal-02181362
v1
|
|
Mutations in human lipoyltransferase gene LIPT1 cause a Leigh disease with secondary deficiency for pyruvate and alpha-ketoglutarate dehydrogenase.
Yohan Soreze
,
Audrey Boutron
,
Florence Habarou
,
Christine Barnerias
,
Luc Nonnenmacher
et al.
Article dans une revue
inserm-00938361
v1
|
|
The histone- and PRMT5-associated protein COPR5 is required for myogenic differentiation
C. Paul
,
C. Sardet
,
E. Fabbrizio
Article dans une revue
hal-02193071
v1
|
|
E4F1 connects the Bmi1-ARF-p53 pathway to epidermal stem cell-dependent skin homeostasis.
Julie Caramel
,
Matthieu Lacroix
,
Laurent Le Cam
,
Claude Sardet
Article dans une revue
inserm-00610180
v1
|
|
E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells.
Elodie Hatchi
,
Genevieve Rodier
,
Matthieu Lacroix
,
Julie Caramel
,
Olivier Kirsh
et al.
Article dans une revue
inserm-00610191
v1
|
|
E4F1 dysfunction results in autophagic cell death in myeloid leukemic cells.
Elodie Hatchi
,
Laurent Le Cam
,
Geneviève Rodier
,
Claude Sardet
Article dans une revue
inserm-00646349
v1
|
|
XIAP-associated factor 1 interacts with and attenuates the trans-activity of four and a Half LIM protein 2
V. P. Tan
,
C. S. Lam
,
J. Wang
,
B. C. Wong
,
W. Zhang
et al.
Article dans une revue
istex
hal-02193331
v1
|
|
Four and a half LIM protein 2 (FHL2) negatively regulates the transcription of E-cadherin through interaction with Snail1
W. Zhang
,
J. Wang
,
B. Zou
,
C. Sardet
,
J. Li
et al.
Article dans une revue
istex
hal-02193500
v1
|
|
E4F1 deficiency results in oxidative stress–mediated cell death of leukemic cells
Elodie Hatchi
,
Genevieve Rodier
,
Matthieu Lacroix
,
Julie Caramel
,
Olivier Kirsh
et al.
Article dans une revue
hal-04766837
v1
|
|
Dual mechanism controls asymmetric spindle position in ascidian germ cell precursors
F. Prodon
,
J. Chenevert
,
C. Hebras
,
R. Dumollard
,
E. Faure
et al.
Article dans une revue
hal-03025982
v1
|
|
Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis.
Matthieu Lacroix
,
Julie Caramel
,
Perrine Goguet-Rubio
,
Laetitia K. Linares
,
Soline Estrach
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (49), pp.21076-81. ⟨10.1073/pnas.1010167107⟩
Article dans une revue
inserm-00555585
v1
|
|
Lessons from interconnected ubiquitylation and acetylation of p53: think metastable networks
Monsef Benkirane
,
Claude Sardet
,
O. Coux
Article dans une revue
hal-00450665
v1
|
|
Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice.
Vanessa Fritz
,
Zohra Benfodda
,
Geneviève Rodier
,
Corinne Henriquet
,
François Iborra
et al.
Article dans une revue
inserm-00544679
v1
|
|
The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells
M. Tardat
,
J. Brustel
,
O. Kirsh
,
C. Lefevbre
,
M. Callanan
et al.
Article dans une revue
istex
hal-02193626
v1
|
|
Four-and-a-half LIM protein 2 promotes invasive potential and epithelial-mesenchymal transition in colon cancer
W. Zhang
,
B. Jiang
,
Z. Guo
,
C. Sardet
,
B. Zou
et al.
Article dans une revue
hal-02193632
v1
|
|
The CDK4-pRB-E2F1 pathway controls insulin secretion.
Jean-Sébastien Annicotte
,
Emilie Blanchet
,
Carine Chavey
,
Irena Iankova
,
Safia Costes
et al.
Article dans une revue
inserm-00418907
v1
|
|
PR‐SET7 and SUV4‐20H regulate H4 lysine‐20 methylation at imprinting control regions in the mouse
Maëlle Pannetier
,
Eric Julien
,
Gunnar Schotta
,
Mathieu Tardat
,
Claude Sardet
et al.
Article dans une revue
hal-02534254
v1
|
|
The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5.
Matthieu Lacroix
,
Selma El Messaoudi
,
Geneviève Rodier
,
Aphonse Le Cam
,
Claude Sardet
et al.
Article dans une revue
hal-00353700
v1
|
|
Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene.
Selma El Messaoudi
,
Eric Fabbrizio
,
Carmen Rodriguez
,
Paul Chuchana
,
Lucas Fauquier
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (36), pp.13351-6. ⟨10.1073/pnas.0605692103⟩
Article dans une revue
hal-00169734
v1
|
|
E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation
L. Le Cam
,
L. K. Linares
,
C. Paul
,
E. Julien
,
M. Lacroix
et al.
Article dans une revue
hal-02262465
v1
|
|
The LIM-only protein FHL2 is a negative regulator of E4F1
C. Paul
,
M. Lacroix
,
I. Iankova
,
E. Julien
,
B. W. Schafer
et al.
Article dans une revue
hal-02262467
v1
|
|
A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner
C. Attwooll
,
S. Oddi
,
P. Cartwright
,
E. Prosperini
,
K. Agger
et al.
Article dans une revue
hal-02262247
v1
|
|
A map of the interactome network of the metazoan C-elegans
S. M. Li
,
C. M. Armstrong
,
N. Bertin
,
H. Ge
,
S. Milstein
et al.
Article dans une revue
hal-02262415
v1
|
|
Identification of the E1A-regulated transcription factor p120(E4F) as an interacting partner of the RASSF1A candidate tumor suppressor gene
S. L. Fenton
,
A. Dallol
,
A. Agathanggelou
,
L. Hesson
,
J. Ahmed-Choudhury
et al.
Article dans une revue
hal-02262407
v1
|
|
The E4F protein is required for mitotic progression during embryonic cell cycles
L. Le Cam
,
M. Lacroix
,
M. A. Ciemerych
,
C. Sardet
,
P. Sicinski
Article dans une revue
hal-02262414
v1
|
|
Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65
Rosemary Kiernan
,
V. Bres
,
Raymond W. M. Ng
,
M. P. Coudart
,
S. El Messaoudi
et al.
Article dans une revue
hal-02239699
v1
|
|
Retinoblastoma protein transcriptional repression through histone deacetylation of a single nucleosome
A. J. Morrison
,
C. Sardet
,
R. E. Herrera
Article dans une revue
hal-02197535
v1
|
|
Negative regulation of transcription by the type II arginine methyltransferase PRMT5
E. Fabbrizio
,
S. El Messaoudi
,
J. Polanowska
,
C. Paul
,
J. R. Cook
et al.
Article dans une revue
hal-02197525
v1
|
|
E2Fs regulate adipocyte differentiation
L. Fajas
,
R. L. Landsberg
,
Y. Huss-Garcia
,
C. Sardet
,
J. A. Lees
et al.
Article dans une revue
hal-02197526
v1
|
|
A B-myb promoter corepressor site facilitates in vivo occupation of the adjacent E2F site by p107-E2F and p130-E2F complexes
S. Catchpole
,
F. Tavner
,
L. Le Cam
,
C. Sardet
,
R. J. Watson
Article dans une revue
hal-02197519
v1
|
|
Retinoblastoma gene proteins: sensors for proliferation signals
E. Fabbrizio
,
C. Sardet
Article dans une revue
hal-02197453
v1
|
|
Cyclin A is a mediator of p120E4F-dependent cell cycle arrest in G1
L. Fajas
,
C. Paul
,
A. Vié
,
S. Estrach
,
R. Medema
et al.
Article dans une revue
hal-02197307
v1
|
|
The periodic down regulation of Cyclin E gene expression from exit of mitosis to end of G(1) is controlled by a deacetylase- and E2F-associated bipartite repressor element
J. Polanowska
,
E. Fabbrizio
,
L. Le Cam
,
Didier Trouche
,
S. Emiliani
et al.
Article dans une revue
hal-02197312
v1
|
|
The retinoblastoma-like protein p130 is involved in the determination of reserve-cells in differentiating myoblasts
Gilles Carnac
,
L. Fajas
,
A. L'Honore
,
C. Sardet
,
N. J. C. Lamb
et al.
Article dans une revue
hal-02196840
v1
|
|
The Rac1-and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin
Jean-Michel Bellanger
,
Catherine Astier
,
Claude Sardet
,
Yasutaka Ohta
,
Thomas P. Stossel
et al.
Article dans une revue
hal-02196838
v1
|
|
Erythroid-specific inhibition of the tal-1 intragenic promoter is due to binding of a repressor to a novel silencer
C. Courtes
,
N. Lecointe
,
L. Le Cam
,
Fulbert Baudoin
,
C. Sardet
et al.
Article dans une revue
hal-02196811
v1
|
|
A CDE/CHR-like element mediates repression of transcription of the mouse RB2 (p130) gene
L. Fajas
,
L. Le Cam
,
J. Polanowska
,
E. Fabbrizio
,
N. Servant
et al.
Article dans une revue
hal-02196816
v1
|
|
Human E2F5 gene is oncogenic in primary rodent cells and is amplified in human breast tumors
J. Polanowska
,
L. Le Cam
,
B. Orsetti
,
H. Valles
,
E. Fabbrizio
et al.
Article dans une revue
istex
hal-02196851
v1
|
|
Cell cycle regulated expression of mammalian CDC6 is dependent on E2F
G. Hateboer
,
A. Wobst
,
B. O. Petersen
,
L. Le Cam
,
E. Vigo
et al.
Molecular and Cellular Biology, 1998, 18 (11), pp.6679--6697
Article dans une revue
hal-02195868
v1
|
|
Regulation of E2F-1 gene expression in avian cells.
X. Espanel
,
L. Le Cam
,
S. North
,
C. Sardet
,
Gilbert Brun
et al.
Oncogene, 1998, 17, pp.585-594
Article dans une revue
hal-00023710
v1
|
|
Activation of E2F-mediated transcription by human T-cell leukemia virus type I Tax protein in a p16(INK4A)-negative T-cell line.
I. Lemasson
,
S. Thébault
,
C. Sardet
,
C. Devaux
,
Jean-Michel Mesnard
Journal of Biological Chemistry, 1998, 273 (36), pp.23598-604
Article dans une revue
hal-00189014
v1
|
|
Regulation of E2F-1 gene expression in avian cells.
X. Espanel
,
L. Lecam
,
S. North
,
C. Sardet
,
G. Brun
et al.
Oncogene, 1998, 17, pp.585-594
Article dans une revue
hal-00314332
v1
|