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Clément Campillo

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Présentation

**Research activities** **Since 2013: Assistant professor, Laboratoire d’Analyse et de Modélisation pour la Biologie et l’Environnement (LAMBE, UMR 8587, Evry), UEVE, Université Paris Saclay** Mechanics of cells probed by AFM (with J. Pelta, S. Labdi and B. Thiebot) \[18\] Oocyte mechanics \[15,16\] Biomimetic systems of the cell cortex \[17,20-23\]. **Sept. 2017: « Habilitation à Diriger les Recherches », U. Paris-Saclay** « Studying and reconstituting the mechanics of the cell cortex » **2012-2013:****Post-doc. Institut Lumière Matière, Lyon** (supervisor: J-P. Rieu) Impedance spectroscopy of cancer cells on microdevices (collaboration with R. Ferrigno, Institut des Nanotechnologies de Lyon and H. Mertani, Centre de Recherche en Cancérologie de Lyon). **June-sept. 2011: Visiting scientist, Gardel Lab, University of Chicago** Micropipette aspiration of Arp2/3 deficient cells \[14\]. **2008-2012: Post-doc. Physico-Chimie Curie (PCC), Paris** (supervisor C. Sykes) Role of membrane inclusions and actin cortex on membrane rheology by membrane nanotube extrusion (collaboration with P. Nassoy, P. Bassereau and P. Sens) \[12,13\] Membrane-cytoskeleton interactions in ciliopathy (collaboration with P. Dupuis-Williams, ESPCI) \[11\] Role of membrane tension in cell motility (collaboration with J. Plastino, PCC) \[9\] Mechanics mouse oocytes (Collaboration with M-E. Terret & M-H Verlhac, CIRB, Collège de France) \[14,16\] **2004-2007: PhD SPrAM - CEA Grenoble** (supervisors B. Pépin-Donat & A. Viallat) “Development of thermo-responsive vesicles from polyNipam systems” \[1,2,8,9,19\] Membrane mechanics of composite vesicles (collaboration with F. Brochard-Wyart, PCC) \[3,6\] Mechanics of composite vesicles (Visiting student in Institut Charles Sadron, Strasbourg, France, 6 months) \[4,5\] **Reviewer** for Nature Communications, Soft Matter, RSC Advances, ACS Omega, Biophysical Journal, New Journal of Physics, PLOS One, Physical Biology (Outstanding Reviewer award for 2018), Biomedical Physics & Engineering Express (IOP), Measurement Science and Technology (IOP) **Member** of GDR CellTiss **Grants & Fellowships** **2018** Coordinator of “High Throughput AFM”, fellowship from DIM Respore/UEVE, 82 k€ **2018 – 2021** Coordinator of “Dynactube”, ANR JCJC (young researcher fellowship, french National Research Agency), 317 k€ **2016** Partner of project AFM-UEVE, grant from region Ile de France (Sesame mi-lourd, DIM NanoK), 126 k€ (supplemented by UEVE 70 k€) **2015-2016**Teaching duty reduction (96h) from “Fonds de Rayonnement de la Recherche”, UEVE **2008-2012**Postdoctoral fellowship from french Cancer Research Association **2004-2007**PhD fellowship from International Research Training Group Grenoble-Strasbourg-Konstanz **Supervision** ***PhDs & Postdocs*** R. Lopes Dos Santos, PhD candidateon the remodelling of membrane nanotubes, from february 2019 M. Liboz, PhD candidateon the mechanics of micropatterned cancer cells, from september 2018 G. Lamour, postdoc (two years fellowship from Genopole, Evry), on the study of membrane nanotubes by AFM, from september 2016 A. Allard, PhD candidate, co-supervised by C. Sykes (PCC) and S. Labdi (LAMBE), on the effect of actin polymerization on membrane nanotubes stability \[21,23\], from january 2016 F. Valentino, PhD defended on September 27th2016, co-supervised since 2014 with C. Sykes (PCC), on actin polymerization on membrane nanotubes \[20,21\]. Now research and development engineer at Phasics (Saclay). ***Undergraduate students*** M. Liboz, Master 2 MAVINOV, U. Paris-Saclay, 4 months, 2018 C. Colne, Licence 3 Chemistry, UEVE, 3 weeks, 2018 T. Groux, Master 1 Chemistry, UEVE, 3 months, 2017 S. Brahimi, Licence 3 Chemistry, UEVE, 3 weeks, 2017 W. Hao, Licence Physique UCBL/ Wuhan University (China), 2 months, 2013 R. Pereira, Master Physical Engineering of Health, Paris 5, 2 months, 2011 G. Guiot, Ecole Polytechnique, 1st year, 3 months, 2010 L. Claverie, Ecole Polytechnique, 1st year, 3 months, 2009 F. Quémeneur, Master « Physics for life sciences», UJF, 4 months, 2005 **Communications** ***Oral presentations*** *Biomaterials Workshop (Invited talk), DIM Respore, Paris,* **2019** *“Shapes in chemistry and biology“Workshop, IPREM, Pau,* **2017** *“Active & Smart Matter Conference”, Syracuse, USA,* **2016** *Invited Seminar, LNIO, UTT, Troyes, France* **2016** *Invited Seminar, LADHYX, Ecole Polytechnique, Palaiseau, France* **2015** *Invited Seminar, LPSM, CEA Saclay* **2015** *GDR CellTiss, Mont Saint Odile,* **2014** *Invited Seminar, IMNC, Orsay* **2014** *Invited Seminar, Lenne Lab, IBDML, Luminy* **2013** *Invited Seminar, Baigl Lab, ENS Paris* **2013** *Invited Seminar, ITAV, Toulouse* **2012** *Invited Seminar, LPMCN, Lyon* **2011** *Invited Seminars, Gardel Lab, Lee Lab, University of Chicago, USA* **2011** *Invited Seminar, LADHYX, Ecole Polytechnique, Palaiseau, France* **2010** *Invited Seminar, Laboratoire de Spectrométrie Physique, Grenoble,* **2010** *GDR CellTiss, Gif-sur-Yvette,* **2009** *Softcomp Annual Meeting, Venice, Italy,* **2009** *12th Young Researchers & Life Sciences meeting, Paris,* **2009** *Biophysical Society 53rd Annual Meeting, Boston, USA,* 3 mars **2009** *Invited Seminar, SprAM, CEA-Grenoble,* **2008** *Softcomp Annual Meeting, Riva del Garda, Italy,* **2008** *Invited Seminar, Laboratoire de Spectrométrie Physique, Grenoble,***2007** *Invited Seminar, Institut Charles Sadron, Strasbourg,* **2007** *Invited Seminar, Spatz group, Max Planck Institut Stuttgart, Germany* **2007** *Congrès de la Société Française de Physique, Grenoble* **2007** *Invited Seminar, Institut Curie, Paris,* **2007** *Congrès Français de Mécanique, Troyes,***2005** *Meeting of the German Colloid Society, Aachen, Germany***2005** ***Poster presentations*** *“Membrane Biophysics of Exo-Endocytosis: from Model Systems to Cells” conference, Mandelieu* **2019** *“International Soft Matter Conference”, Grenoble* **2016** *“Physics & Biological Systems” conference, Gif-sur-Yvette* **2014** *FPGG Spring Symposium,* **2011** *Biophysical Society Conference “Actin, Cytoskeleton and Nucleus”, Singapore,* **2010** *“International Soft Matter Conference”, Granada, Spain,* **2010** *Pierre-Gilles de Gennes Winter School, Cargese,* **2008** *“Fundamental and Applied Macromolecular Science”, Strasbourg* **2007**

Publications

marie-emilie-terret

Mechanical Characterization of Murine Oocytes by Atomic Force Microscopy

Rose Bulteau , Lucie Barbier , Guillaume Lamour , Tristan Piolot , Elsa Labrune
Methods in Molecular Biology, 2024, Methods in Molecular Biology, 2740, pp.117-124. ⟨10.1007/978-1-0716-3557-5_7⟩
Article dans une revue hal-04476753v1
Image document

Methods for Assessing Oocyte Quality: A Review of Literature

Yassir Lemseffer , Marie-Emilie Terret , Clément Campillo , Elsa Labrune
Biomedicines, 2022, 10 (9), pp.2184. ⟨10.3390/biomedicines10092184⟩
Article dans une revue hal-03811993v1
Image document

Artificially decreasing cortical tension generates aneuploidy in mouse oocytes

Isma Bennabi , Flora Crozet , Elvira Nikalayevich , Agathe Chaigne , Gaëlle Letort
Nature Communications, 2020, 11, ⟨10.1038/s41467-020-15470-y⟩
Article dans une revue hal-03003434v1
Image document

F-actin mechanics control spindle centring in the mouse zygote

Agathe Chaigne , Clément Campillo , Raphaël Voituriez , Nir S. Gov , C. Sykes
Nature Communications, 2016, 7, pp.10253. ⟨10.1038/ncomms10253⟩
Article dans une revue hal-01276390v1
Image document

A narrow window of cortical tension guides asymmetric spindle positioning in the mouse oocyte

Agathe Chaigne , Clément Campillo , Nir S Gov , Raphaël Voituriez , C. Sykes
Nature Communications, 2015, 6 (1), pp.6027/1-10. ⟨10.1038/ncomms7027⟩
Article dans une revue hal-02065107v1

A soft cortex is essential for asymmetric spindle positioning in mouse oocytes

Agathe Chaigne , Clément Campillo , Nir S. Gov , Raphael Voituriez , Jessica Azoury
Nature Cell Biology, 2013, 15 (8), pp.958-966. ⟨10.1038/ncb2799⟩
Article dans une revue hal-00994646v1

Characterization of a novel subcortical actin layer regulating spindle positioning and cortical plasticity in mouse oocytes

Agathe Chaigne , Clément Campillo , Jessica Azoury , Claudia Umana-Diaz , Pierre Nassoy
Annual Meeting of the American-Society-for-Cell-Biology (ASCB), Dec 2011, Denver, United States. pp.85
Communication dans un congrès hal-00995023v1