Clement Mettling

Publications

Article dans une revue (38)

Perceptual Advantages of People Living in Semeru Volcanic Areas, Indonesia: An MRCV (Multiple Response Categorical Variable) Analysis Yanti Ariyanti,Sarah Nila,Winati Nurhayu,Dimitri Dubois,Kanthi Arum Widayatiet al. HAYATI Journal of Biosciences, 2026, 33 (3), pp.739-749. ⟨10.4308/hjb.33.3.739-749⟩ Article dans une revue hal-05492915v1
γ-Aminobutyric Acid-Induced Monocytic Reactive Oxygen Species Impair CD4 Restoration in Treated Adults With HIV-1 Mehwish Younas,Sandrine Gimenez,Yea-Lih Lin,Clément Mettling,Domenico Maioranoet al. Journal of Infectious Diseases, In press, pp.jiaf058. ⟨10.1093/infdis/jiaf058⟩ Article dans une revue hal-05057438v1
Low Percentage of Perforin-Expressing NK Cells during Severe SARS-CoV-2 Infection: Consumption Rather than Primary Deficiency Lucy Kundura,Renaud Cezar,Emma Ballongue,Sonia André,Moïse Michelet al. Journal of Immunology, 2024, 212 (7), pp.1105 - 1112. ⟨10.4049/jimmunol.2300359⟩ Article dans une revue hal-04748173v1
The EBI2 receptor is coexpressed with CCR5 in CD4+ T cells and boosts HIV-1 R5 replication Adeline Guigues,Sandrine Gimenez,Clément Mettling,Damien Maurel,Etienne Doumazaneet al. AIDS. Official journal of the international AIDS Society, 2024, 38 (10), pp.1449-1459. ⟨10.1097/QAD.0000000000003931⟩ Article dans une revue hal-04748558v1
MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling Hervé Técher,Diyavarshini Gopaul,Jonathan Heuzé,Nail Bouzalmad,Baptiste Lerayet al. Nature Communications, 2024, 15 (1), pp.5423. ⟨10.1038/s41467-024-49740-w⟩ Article dans une revue hal-04748159v1
A Tripartite Complex HIV-1 Tat-Cyclophilin A-Capsid Protein Enables Tat Encapsidation That Is Required for HIV-1 Infectivity Malvina Schatz,Laetitia Marty,Camille Ounadjela,Phuoc Bao Viet Tong,Ilaria Cardaceet al. Journal of Virology, 2023, 97 (4), ⟨10.1128/jvi.00278-23⟩ Article dans une revue hal-04106774v1
The effect of the 7R allele at the DRD4 locus on risk tolerance is independent of background risk in Senegalese fishermen Gwen-Jirō Clochard,Aby Mbengue,Clément Mettling,Birane Diouf,Charlotte Faurieet al. Scientific Reports, 2023, 13 (1), pp.622. ⟨10.1038/s41598-022-27002-3⟩ Article dans une revue hal-03954770v1
Angiotensin II induces reactive oxygen species, DNA damage, and T-cell apoptosis in severe COVID-19 Lucy Kundura,Sandrine Gimenez,Renaud Cezar,Sonia André,Mehwish Younaset al. Journal of Allergy and Clinical Immunology, 2022, 150 (3), pp.594-603.e2. ⟨10.1016/j.jaci.2022.06.020⟩ Article dans une revue hal-03837641v1
Genomic amplification of chromosome 20q13.33 is the early biomarker for the development of sporadic colorectal carcinoma Vo-Minh-Hoang Bui,Clément Mettling,Jonathan Jou,H Sunny Sun BMC Medical Genomics, 2020, 13, ⟨10.1186/s12920-020-00776-z⟩ Article dans une revue hal-03078496v1
Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites Alexy Promonet,Ismaël Padioleau,Yaqun Liu,Lionel A. Sanz,Anna Biernackaet al. Nature Communications, 2020, 11 (1), pp.3940. ⟨10.1038/s41467-020-17858-2⟩ Article dans une revue hal-02931000v1
SAMHD1 agit sur les fourches de réplication bloquées pour empêcher l’induction d’interféron F. Coquel,M. Silva,H. Técher,K. Zadorozhny,S. Sharmaet al. Comptes Rendus. Biologies, 2020, 343 (1), pp.9-21. ⟨10.5802/crbiol.10⟩ Article dans une revue hal-03083188v1
SAMHD1 agit sur les fourches de réplication bloquées pour empêcher l’induction d’interféron F. Coquel,M. Silva,H. Técher,K. Zadorozhny,S. Sharmaet al. Comptes Rendus. Biologies, 2020, 343 (1), pp.9-21. ⟨10.5802/crbiol.10⟩ Article dans une revue hal-03078628v1
Cyclophilin A enables specific HIV-1 Tat palmitoylation and accumulation in uninfected cells Christophe Chopard,Phuoc Bao Viet Tong,Petra Toth,Malvina Schatz,Hocine Yezidet al. Nature Communications, 2018, 9 (1), pp.2251. ⟨10.1038/s41467-018-04674-y⟩ Article dans une revue hal-02146273v1
Reversing HIV latency via sphingosine-1-phosphate receptor 1 signaling Charline Duquenne,Sandrine Gimenez,Adeline Guigues,Benjamin Viala,Caroline Boulouiset al. AIDS. Official journal of the international AIDS Society, 2017, 31 (18), pp.2443 - 2454. ⟨10.1097/QAD.0000000000001649⟩ Article dans une revue hal-01635726v1
Autophagy-associated dengue vesicles promote viral transmission avoiding antibody neutralization Yw Wu,C Mettling,Sr Wu,Cy Yu,Gc Pernget al. Scientific Reports, 2016, 6, pp.32243. ⟨10.1038/srep32243⟩ Article dans une revue hal-01377127v1
Evidence of genotypic adaptation to the exposure to volcanic risk at the dopamine receptor DRD4 locus Charlotte Faurie,Clement Mettling,Mohamed Ali Bchir,Danang Hadmoko,Carine Heitzet al. Scientific Reports, 2016, 6 (37745), 7 p. ⟨10.1038/srep37745⟩ Article dans une revue hal-02062364v1
HIV-1 Tat inhibits phagocytosis by preventing the recruitment of Cdc42 to the phagocytic cup Solène Debaisieux,Simon Lachambre,Antoine Gross,Clément Mettling,Sébastien Besteiroet al. Nature Communications, 2015, 6 (1), pp.6211. ⟨10.1038/ncomms7211⟩ Article dans une revue hal-02146268v1
The Two Human CXCR4 Isoforms Display Different HIV Receptor Activities: Consequences for the Emergence of X4 Strains C Duquenne,C Psomas,S Gimenez,A Guigues,Mj Carleset al. Journal of Immunology, 2014, 193 (8), pp.4188-4194. ⟨10.4049/jimmunol.1303298⟩ Article dans une revue hal-01074809v1
Combined Phytochemistry and Chemotaxis Assays for Identification and Mechanistic Analysis of Anti-Inflammatory Phytochemicals in Fallopia japonica Ming-Yi Shen,Yan-Jun Liu,Ming-Jaw Don,Hsien-Yueh Liu,Zeng-Weng Chenet al. PLoS ONE, 2011, 6 (11), pp.e27480. ⟨10.1371/journal.pone.0027480⟩ Article dans une revue hal-00645719v1
Strategy for anti-aquaporin-4 auto-antibody identification and quantification using a new cell-based assay I. de Vidi,G. Boursier,N. Delouche,P. Portales,E. Cadarset al. Clinical Immunology, 2011, 138 (3), pp.239-246. ⟨10.1016/j.clim.2010.11.012⟩ Article dans une revue istex hal-00575112v1
Phosphatidylinositol-(4,5)-bisphosphate enables efficient secretion of HIV-1 Tat by infected T-cells Fabienne Rayne,Solène Debaisieux,Hocine Yezid,Yea-Lih Lin,Clément Mettlinget al. EMBO Journal, 2010, 29 (8), pp.1348-1362. ⟨10.1038/emboj.2010.32⟩ Article dans une revue hal-02147182v1
The chemokine CCL5 regulates the in vivo cel surface of its receptor, CCR5 Yea-Lih Lin,C. Mettling,P. Portales,Roman Rouzier,J. Clotet al. AIDS. Official journal of the international AIDS Society, 2008, 22 (3), pp.430-432. ⟨10.1097/QAD.0b013e3282f46a6f⟩ Article dans une revue hal-00206135v1
Galphai protein-dependant extracellular signal-regulated kinase-1/2 activation is required for HIV-1 reverse transcription C. Mettling,C. Desmetz,Al Fiser,B. Reant,P. Corbeauet al. AIDS. Official journal of the international AIDS Society, 2008, 13, pp.1569-1576. ⟨10.1097/QAD.0b013e32830abdaf⟩ Article dans une revue hal-00322412v1
Suv39H1 and HP1**g** are responsible for chromatin-mediated HIV-1 transcriptional silencing and post integration latency. I. Du Chene,E. Basyuk,Yea-Lih Lin,R. Triboulet,A. Knezevichet al. EMBO Journal, 2007, 26 (2), pp.424-435. ⟨10.1038/sj.emboj.7601517⟩ Article dans une revue hal-00130455v1
Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance N. Bakkour,Yl. Lin,S. Maire,L. Ayadi,Florence Mahuteau-Betzeret al. PLoS Pathogens, 2007, 3 (10), pp.1530-1539. ⟨10.1371/journal.ppat.0030159⟩ Article dans une revue hal-00259118v1
Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance N. Bakkour,Yea-Lih Lin,S. Maire,L. Ayadi,Florence Mahuteau-Betzeret al. PLoS Pathogens, 2007, 3 (10), pp.e159. ⟨10.1371/journal.ppat.0030159⟩ Article dans une revue hal-00185296v1
Unintegrated HIV-1 provides an inducible and functional reservoir in untreated and highly active antiretroviral therapy-treated patients G. Petitjean,Y. Al Tabaa,E. Tuaillon,C. Mettling,V. Baillatet al. Retrovirology, 2007, 4, pp.60. ⟨10.1186/1742-4690-4-60⟩ Article dans une revue hal-00194043v1
Cell surface CCR5 density determines the intensity of T cell migration towards rheumatoid arthritis synoviocytes. C. Desmetz,Yea-Lih Lin,C. Mettling,P. Portales,D. Noelet al. Clinical Immunology, 2007, 123 (2), pp.148-154. ⟨10.1016/j.clim.2007.01.004⟩ Article dans une revue istex hal-00148014v1
The efficiency of R5 HIV-1 infection is determined by CD4 T-cell surface CCR5 density through Galphai-protein signalling Yea-Lih Lin,C. Mettling,P. Portales,B. Reant,V. Robert-Hebmannet al. AIDS. Official journal of the international AIDS Society, 2006, 20, pp.1369-1377. ⟨10.1097/01.aids.0000233570.51899.e2⟩ Article dans une revue hal-00082331v1
The strength of the chemotactic response to a CCR5 binding chemokine is determined by the level of cell surface CCR5 density. C. Desmetz,Yea-Lih Lin,C. Mettling,P. Portales,H. Rabesandratanaet al. Immunology, 2006, 119 (4), pp.551-561. ⟨10.1111/j.1365-2567.2006.02470.x⟩ Article dans une revue hal-00122082v1
Structure-based design, synthesis, and biological evaluation of novel inhibitors of human cyclophilin A. Jf Guichou,J. Viaud,C. Mettling,G. Subra,Yea-Lih Linet al. Journal of Medicinal Chemistry, 2006, 49 (3), pp.900-910. ⟨10.1021/jm050716a⟩ Article dans une revue hal-00113407v1
Effects of virion surface gp120 density on infection by HIV-1 and viral production by infected cells E. Bachrach,H. Dreja,Y. L. Lin,C. Mettling,V. Pinetet al. Virology, 2005, 332 (1), pp.418--29. ⟨10.1016/j.virol.2004.11.031⟩ Article dans une revue hal-02262222v1
Inhibition of PrPSc formation by lentiviral gene transfer of PrP containing dominant negative mutations. Carole Crozet,Yea-Lih Lin,Clément Mettling,Chantal Mourton-Gilles,Pierre Corbeauet al. Journal of Cell Science, 2004, 117 (Pt 23), pp.5591-7. ⟨10.1242/jcs.01484⟩ Article dans une revue inserm-00143203v1
Regulatory elements and interactions in theDrosophila 68C glue gene cluster Marianne Martin,Clément Mettling,Angela Giangrande,Claude Ruiz,Geoff Richards Developmental Genetics, 1989, 10 (3), pp.189-197. ⟨10.1002/dvg.1020100308⟩ Article dans une revue istex hal-03478180v1
Drosophila Sgs3 TATA: effects of point mutations on expression in vivo and protein binding in vitro with staged nuclear extracts. A Giangrande,C Mettling,M Martin,C Ruiz,G Richards EMBO Journal, 1989, 8 (11), pp.3459-66 Article dans une revue hal-03478183v1
The use of oligonucleotide probes in studies of insect gene activity in development Clément Mettling,Angela Giangrande,Geoff Richards Journal of Insect Physiology, 1988, 34 (7), pp.679-684. ⟨10.1016/0022-1910(88)90077-7⟩ Article dans une revue istex hal-03478161v1
Sps-3 transcript levels are determined by multiple remote sequence elements. A Giangrande,C Mettling,G Richards EMBO Journal, 1987, 6 (10), pp.3079-84 Article dans une revue hal-03475626v1
The Drosophila sgs3 gene: an in-vivo test of intron function Clément Mettling,Angela Giangrande,Geoff Richards Journal of Molecular Biology, 1987, 196 (1), pp.223-226. ⟨10.1016/0022-2836(87)90523-7⟩ Article dans une revue istex hal-03475625v1

Pré-publication, Document de travail (1)

Regulation of oncogene-induced senescence by the MRE11 and TREX1 nucleases Hervé Técher,Diyavarshini Gopaul,Jonathan Heuzé,Baptiste Leray,Audrey Vernetet al. 2023 Pré-publication, Document de travail hal-04315770v1