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Eric Leclerc

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Generation of β-like cell subtypes from differentiated human induced pluripotent stem cells in 3D spheroids

Lisa Morisseau , Fumiya Tokito , Stéphane Poulain , Valérie Plaisance , Valerie Pawlowski
Molecular Omics, 2023, 19 (10), pp.810-822. ⟨10.1039/D3MO00050H⟩
Journal articles hal-04209565v1
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Multi‐omics analysis of hiPSCs‐derived HLCs matured on‐chip revealed patterns typical of liver regeneration

Mathieu Danoy , Yannick Tauran , Stéphane Poulain , Rachid Jellali , Johanna Bruce
Biotechnology and Bioengineering, In press, ⟨10.1002/bit.27667⟩
Journal articles hal-03288795v1
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Development of a pancreas-liver organ-on-chip coculture model for organ-to-organ interaction studies

Amal Essaouiba , Teru Okitsu , R. Kinoshita , Rachid Jellali , Yasuyuki Sakai
Biochemical Engineering Journal, 2020, 164, pp.107783. ⟨10.1016/j.bej.2020.107783⟩
Journal articles hal-03095499v1

Optimized protocol for the hepatic differentiation of induced pluripotent stem cells in a fluidic microenvironment

Mathieu Danoy , Myriam Lereau Bernier , Keiichi Kimura , Stéphane Poulain , Sachi Kato
Biotechnology and Bioengineering, 2019, 116 (7), pp.1762-1776. ⟨10.1002/bit.26970⟩
Journal articles hal-02357453v1
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Integration of metabolomic and transcriptomic profiling to compare two protocols of differentiation of human induced pluripotent stem cells into hepatocytes

Rachid Jellali , Stéphane Poulain , Myriam Lereau Bernier , Françoise Gilard , Yannick Y. Tauran
Process Biochemistry, 2019, 88, pp.139-147. ⟨10.1016/j.procbio.2019.09.034⟩
Journal articles hal-02357452v1

Investigation of the hepatic respiration and liver zonation on rat hepatocytes using an integrated oxygen biosensor in a microscale device

Satomi Matsumoto , Astia Safitri , Mathieu Danoy , Toshiro Maekawa , Haruyuki Kinoshita
Biotechnology Progress, 2019, 35 (5), ⟨10.1002/btpr.2854⟩
Journal articles hal-02357455v1

Simplest Chemosensor Array for Phosphorylated Saccharides

Yui Sasaki , Eric Leclerc , Vahid Hamedpour , Riku Kubota , Shin-Ya Takizawa
Analytical Chemistry, 2019, ⟨10.1021/acs.analchem.9b03578⟩
Journal articles hal-02369560v1

Profiling of derived-hepatocyte progenitors from induced pluripotent stem cells using nanoCAGE promoter analysis

Myriam Lereau Bernier , Stéphane Poulain , Yannick Y. Tauran , Mathieu Danoy , Marie Shinohara
Biochemical Engineering Journal, 2019, 142, pp.7-17. ⟨10.1016/j.bej.2018.11.001⟩
Journal articles hal-02357456v1
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Analysis of the transcription factors and their regulatory roles during a step-by-step differentiation of induced pluripotent stem cells into hepatocyte-like cells

Yannick Y. Tauran , Stéphane Poulain , Myriam Lereau-Bernier , Mathieu Danoy , Marie Shinohara
Molecular Omics, 2019, ⟨10.1039/C9MO00122K⟩
Journal articles hal-02357458v1
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Effects of DDT and permethrin on rat hepatocytes cultivated in microfluidic biochips: Metabolomics and gene expression study

Rachid Jellali , Perrine Zeller , Françoise Gilard , Audrey Legendre , Marie José Fleury
Environmental Toxicology and Pharmacology, 2018, 59, pp.1-12. ⟨10.1016/j.etap.2018.02.004⟩
Journal articles hal-02357463v1

Metabolomics-on-a-chip approach to study hepatotoxicity of DDT, permethrin and their mixtures

Rachid Jellali , Françoise Gilard , Vittoria Pandolfi , Audrey Legendre , Marie-José Fleury
Journal of Applied Toxicology, 2018, 38 (8), pp.1121-1134. ⟨10.1002/jat.3624⟩
Journal articles hal-02357461v1

Integration of an oxygen sensor into a polydymethylsiloxane hepatic culture device for two-dimensional gradient characterization

Satomi Matsumoto , Eric Leclerc , Toshiro Maekawa , Haruyuki Kinoshita , Marie Shinohara
Sensors and Actuators B: Chemical, 2018, 273, pp.1062-1069. ⟨10.1016/j.snb.2018.05.053⟩
Journal articles hal-02357459v1

Water-in-oil droplet formation in a flow-focusing microsystem using pressure- and flow rate-driven pumps

Sarah Lignel , Anne-Virginie Salsac , Audrey Drelich , Eric Leclerc , Isabelle Pezron
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2017, 531, pp.164-172. ⟨10.1016/j.colsurfa.2017.07.065⟩
Journal articles hal-02357482v1

Thin-film-transistor array: an exploratory attempt for high throughput cell manipulation using electrowetting principle

F Azam Shaik , G Cathcart , S Ihida , M Lereau-Bernier , Eric Leclerc
Journal of Micromechanics and Microengineering, 2017, 27 (5), pp.054001. ⟨10.1088/1361-6439/aa66e8⟩
Journal articles hal-02357490v1

Online monitoring of hepatic rat metabolism by coupling a liver biochip and a mass spectrometer

Franck Merlier , Rachid Jellali , Eric Leclerc
Analyst, 2017, 142 (19), pp.3747-3757. ⟨10.1039/C7AN00973A⟩
Journal articles hal-01988812v1

In vitro cyto-biocompatibility study of thin-film transistors substrates using an organotypic culture method

Eric Leclerc , Jean-Luc Duval , Christophe Egles , Satoshi Ihida , Hiroshi Toshiyoshi
Journal of Materials Science: Materials in Medicine, 2017, 28 (1), pp.4. ⟨10.1007/s10856-016-5815-1⟩
Journal articles hal-01955190v1

Transient behavior and relaxation of microcapsules with a cross-linked human serum albumin membrane

Pierre-Yves Gires , Dominique Barthès-Biesel , Eric Leclerc , Anne-Virginie Salsac
Journal of the mechanical behavior of biomedical materials, 2016, 58, pp.2-10. ⟨10.1016/j.jmbbm.2015.09.008⟩
Journal articles hal-02019566v1

Investigation of ifosfamide nephrotoxicity induced in a liver-kidney co-culture biochip.

Leila Choucha-Snouber , Caroline Aninat , Laurent Grsicom , Geoffrey Madalinski , Céline Brochot
Biotechnology and Bioengineering, 2013, 110 (2), pp.597-608. ⟨10.1002/bit.24707⟩
Journal articles inserm-00864839v1

Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips

Régis Baudoin , Jean-Matthieu Prot , Grégory Nicolas , Jessy Brocheton , Céline Brochot
Xenobiotica, 2013, 43 (2), pp.140-152. ⟨10.3109/00498254.2012.706725⟩
Journal articles ineris-00963431v1

Microfluidic technique for measuring microcapsules.

Anne-Virginie Salsac , Eric Leclerc , Dominique Barthès-Biesel
Bioencapsulation Innovations, 2013
Journal articles hal-02019778v1
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Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: Application to acetaminophen injury

Jean-Matthieu Prot , Andrei Bunescu , Bénédicte Elena-Herrmann , Caroline Aninat , Leila Choucha Snouber
Toxicology and Applied Pharmacology, 2012, 259 (3), pp.270-280. ⟨10.1016/j.taap.2011.12.017⟩
Journal articles hal-00699551v1

Investigation of Oleic Acid, Palmitic Acid and their mixture on the development of hepatic steatosis using liver-on-chip technology

Lisa Morisseau , C. Legallais , Amar Abderrahmani , Yasuyoshi Sakai , Eric Leclerc
49th ESAO Congress, Aug 2023, Bergamo, Italy
Conference papers hal-04476949v1

Cryogel integrated microchip : towards a human 3D model of liver cancer

Lilandra Boulais , Rachid Jellali , Ulysse Pereira , Patrick Paullier , Eric Leclerc
Cancer Cells-on-Chip 2, Mar 2019, Lyon, France
Conference papers hal-04475771v1

Investigation of the Behavior of Rat Pancreatic Islets in an Organ-On-Chip Model

Amal Essaouiba , Teru Okitsu , Rachid Jellali , Marie Shinohara , Mathieu Danoy
IFAO-JSAO Congress, Nov 2019, Osaka (JP), Japan
Conference papers hal-04475774v1

Liver on chip platform: key questions following 15 years of development

C. Legallais , Rachid Jellali , Eric Leclerc
International MicroNanoconference, Dec 2018, Amsterdam, Netherlands
Conference papers hal-04475722v1

Relation entre stabilité des émulsions eau-dans-huile et cristallisation de gouttes d’eau générées par microfluidique.

Audrey Drelich , Sarah Lignel , Danièle Clausse , Anne-Virginie Salsac , Eric Leclerc
Journées de Calorimétrie et d’Analyse Thermique JAT 2017, May 2017, Rueil-Malmaison, France
Conference papers hal-02491826v1

Pharmaco-metabonomic investigation of acetaminophen toxicity on rat primary hepatocytes in microfluidic biochips

Claire Lopez , Mathilde Bayet-Robert , Marc-Emmanuel Dumas , Jean-Matthieu Prot , Alexandre R.R. Pery
7e Journées scientifiques du Réseau Français de Métabolomique et Fluxomique (RFMF), Jun 2013, Amiens, France
Conference papers hal-00980023v1

Automatic evaluation of the elastic modulus of a capsule membrane

T.X. Chu , Anne-Virginie Salsac , Eric Leclerc , Dominique Barthès-Biesel
Knowledge and Systems Engineering. Advances in Intelligent Systems and Computing, 245, 2013, 978-3-319-02820-0. ⟨10.1007/978-3-319-02821-7_34⟩
Book sections hal-02019807v1