Cynthia Marie-Claire

Documents

Publications

	Decreased telomere length in a subgroup of young individuals with bipolar disorders: replication in the FACE-BD cohort and association with the shelterin component POT1 Luana Spano , Cynthia Marie-Claire , Ophélia Godin , Apolline Lebras , Cindie Courtin Translational Psychiatry, 2024, 14 (1), pp.131. ⟨10.1038/s41398-024-02824-z⟩ Journal articles hal-04492634v1
	Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study Anna Ou , Sara Rosenthal , Mazda Adli , Kazufumi Akiyama , Nirmala Akula Translational Psychiatry, 2024, 14, pp.109. ⟨10.1038/s41398-024-02811-4⟩ Journal articles hal-04598121v1
	Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder Marisol Herrera-Rivero , Karina Gutiérrez-Fragoso , Anbupalam Thalamuthu , Azmeraw Amare , Mazda Adli Research Square - Preprint, 2023, pp.rs.3.rs-3068352. ⟨10.21203/rs.3.rs-3068352/v1⟩ Journal articles inserm-04198049v1
	Risperidone response in patients with schizophrenia drives DNA methylation changes in immune and neuronal systems Ana Lokmer , Charanraj Goud Alladi , Réjane Troudet , Delphine Bacq-Daian , Anne Boland-Auge Epigenomics, 2023, ⟨10.2217/epi-2023-0017⟩ Journal articles inserm-04044562v1
	Accelerated aging in bipolar disorders: An exploratory study of six epigenetic clocks Céline Bourdon , Bruno Etain , Luana Spano , Raoul Belzeaux , Marion Leboyer Psychiatry Research, 2023, 327, pp.115373. ⟨10.1016/j.psychres.2023.115373⟩ Journal articles hal-04181925v2
	Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder Azmeraw T Amare , Anbupalam Thalamuthu , Klaus Oliver Schubert , Janice M Fullerton , Muktar Ahmed Molecular Psychiatry, 2023, ⟨10.1038/s41380-023-02149-1⟩ Journal articles inserm-04165233v1
	Associations between circadian misalignment and telomere length in BD: an actigraphy study Luana Spano , Vincent Hennion , Cynthia Marie-Claire , Frank Bellivier , Jan Scott International Journal of Bipolar Disorders, 2022, 10 (1), pp.14. ⟨10.1186/s40345-022-00260-w⟩ Journal articles hal-03767739v1
	Methylomic Biomarkers of Lithium Response in Bipolar Disorder: A Proof of Transferability Study Cynthia Marie-Claire , Cindie Courtin , Frank Bellivier , Jan Scott , Bruno Etain Pharmaceuticals, 2022, 15 (2), pp.133. ⟨10.3390/ph15020133⟩ Journal articles hal-03806366v1
	Telomere length and mitochondrial DNA copy number in bipolar disorder: a sibling study. L. Spano , B. Etain , J-L Laplanche , M. Leboyer , S. Gard World Journal of Biological Psychiatry, 2022, pp.1-25. ⟨10.1080/15622975.2022.2131907⟩ Journal articles hal-03798566v1
	Plasma tau, NfL, GFAP and UCHL1 as candidate biomarkers of alcohol withdrawal-associated brain damage: A pilot study Virgile Clergue-Duval , Agathe Vrillon , Jerome Jeanblanc , Frank Questel , Julien Azuar Addiction Biology, 2022, 27 (6), ⟨10.1111/adb.13232⟩ Journal articles hal-03783445v1
	The molecular pathophysiology of mood disorders: From the analysis of single molecular layers to multi-omic integration Amazigh Mokhtari , Baptiste Porte , Raoul Belzeaux , Bruno Etain , El Cherif Ibrahim Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2022, 116, pp.110520. ⟨10.1016/j.pnpbp.2022.110520⟩ Journal articles hal-03568945v1
	Telomere length and mitochondrial DNA copy number in bipolar disorder: identification of a subgroup of young individuals with accelerated cellular aging L. Spano , B. Etain , M. Meyrel , V. Hennion , G. Gross Translational Psychiatry, 2022, 12 (1), pp.135. ⟨10.1038/s41398-022-01891-4⟩ Journal articles hal-03767733v1
	Biomarkers of Relapse in Cocaine Use Disorder: A Narrative Review Margaux Poireau , Thomas Milpied , Angéline Maillard , Christine Delmaire , Emmanuelle Volle Brain Sciences, 2022, 12 (8), pp.1013. ⟨10.3390/brainsci12081013⟩ Journal articles hal-03784434v1
	Individual differences in cocaine-induced conditioned place preference in male rats: Behavioral and transcriptomic evidence Luisa Alessandra Atehortua Martinez , Emmanuel Curis , Nawel Mekdad , Claire Larrieu , Cindie Courtin Journal of Psychopharmacology, 2022, 36 (10), pp.1161-1175. ⟨10.1177/02698811221123047⟩ Journal articles hal-03784427v1
	Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder Nadia Cattane , Cindie Courtin , Elisa Mombelli , Carlo Maj , Cristina Mora BMC Psychiatry, 2022, 22 (1), pp.665. ⟨10.1186/s12888-022-04286-3⟩ Journal articles hal-03834253v1
	Mini review: Recent advances on epigenetic effects of lithium Cynthia Marie-Claire , B. Etain , F. Bellivier Neuroscience Letters, 2021, 761, pp.136116. ⟨10.1016/j.neulet.2021.136116⟩ Journal articles hal-03357149v1
	Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients Cynthia Marie-Claire , Klaus Oliver Schubert , Anbupalam Thalamuthu , Azmeraw Amare , Joseph Frank Translational Psychiatry, 2021, 11 (1), pp.606. ⟨10.1038/s41398-021-01702-2⟩ Journal articles hal-03568953v1
	Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: A critical multi‐disciplinary literature review and agenda for future research from the ISBD task force on chronobiology Cynthia Marie-Claire , Diane Grillault Laroche , Ophélia Godin , Raoul Belzeaux , Katia M'Bailara Bipolar Disorders, 2021, pp.1-32. ⟨10.1111/bdi.13165⟩ Journal articles hal-03568951v1
	Network of co-expressed circadian genes, childhood maltreatment and sleep quality in bipolar disorders D. Grillault Laroche , E. Curis , F. Bellivier , C. Nepost , G. Gross Chronobiology International, 2021, pp.1-8. ⟨10.1080/07420528.2021.1903028⟩ Journal articles hal-03239600v1
	Biomarkers to predict staging and treatment response in opioid dependence: A narrative review Florence Vorspan , Cynthia Marie-Claire , Frank Bellivier , Vanessa Bloch Drug Development Research, 2021, ⟨10.1002/ddr.21789⟩ Journal articles hal-03123197v1
	A Comparison of Different Approaches to Clinical Phenotyping of Lithium Response: A Proof of Principle Study Employing Genetic Variants of Three Candidate Circadian Genes Jan Scott , Mohamed Lajnef , Romain Icick , Frank Bellivier , Cynthia Marie-Claire Pharmaceuticals, 2021, 14 (11), pp.1072. ⟨10.3390/ph14111072⟩ Journal articles hal-03568955v1
	Clinical Trials of Cannabidiol for Substance Use Disorders: Outcome Measures, Surrogate Endpoints, and Biomarkers Alix Morel , Pierre Lebard , Alexandra Dereux , Julien Azuar , Frank Questel Frontiers in Psychiatry, 2021, 12, pp.565617. ⟨10.3389/fpsyt.2021.565617⟩ Journal articles hal-03239604v1
	Clustering suicidal phenotypes and genetic associations with brain-derived neurotrophic factor in patients with substance use disorders Romain Icick , Vanessa Bloch , Nathalie Prince , Emily Karsinti , Jean-Pierre Lépine Translational Psychiatry, 2021, 11 (1), pp.72. ⟨10.1038/s41398-021-01200-5⟩ Journal articles hal-03123199v1
	Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: A critical multi‐disciplinary literature review and agenda for future research from the ISBD task force on chronobiology Michael Mccarthy , John Gottlieb , Robert Gonzalez , Colleen Mcclung , Lauren Alloy Bipolar Disorders, 2021, 24 (3), pp.232-263. ⟨10.1111/bdi.13165⟩ Journal articles hal-03806382v1
	A DNA methylation signature discriminates between excellent and non-response to lithium in patients with bipolar disorder type 1 Cynthia Marie-Claire , François-Xavier Lejeune , Emeline Mundwiller , Damien Ulveling , Ivan Moszer Scientific Reports, 2020, 10 (1), pp.12239. ⟨10.1038/s41598-020-69073-0⟩ Journal articles inserm-02937821v1
	Childhood maltreatment and HPA axis gene expression in bipolar disorders: A gene network analysis. D Grillault Laroche , E Curis , F Bellivier , C Nepost , Cindie Courtin Psychoneuroendocrinology, 2020, 120, pp.104753. ⟨10.1016/j.psyneuen.2020.104753⟩ Journal articles hal-03024265v1
	Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances. Florence Vorspan , Romain Icick , Nawel Mekdad , Cindie Courtin , Vanessa Bloch Translational Psychiatry, 2020, 10 (1), pp.381. ⟨10.1038/s41398-020-01050-7⟩ Journal articles hal-03024249v1
	Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances Florence Vorspan , Romain Icick , Nawel Mekdad , Cindie Courtin , Vanessa Bloch Translational Psychiatry, 2020, 10 (1), pp.381. ⟨10.1038/s41398-020-01050-7⟩ Journal articles hal-03893616v1
	Selecting reference genes in RT-qPCR based on equivalence tests: a network based approach Emmanuel Curis , Calypso Nepost , Diane Grillault Laroche , Cindie Courtin , Jean-Louis Laplanche Scientific Reports, 2019, 9 (1), pp.16231. ⟨10.1038/s41598-019-52217-2⟩ Journal articles hal-03032928v1
	QT length during methadone maintenance treatment: gene × dose interaction El-Hadi Zerdazi , Florence Vorspan , Andries Marees , François Naccache , Jean-Pierre Lepine Fundamental & Clinical Pharmacology, 2019, 33 (1), pp.96 - 106. ⟨10.1111/fcp.12405⟩ Journal articles hal-03032957v1
	Increased plasma levels of high mobility group box 1 protein in patients with bipolar disorder: A pilot study Cynthia Marie-Claire , Cindie Courtin , Emmanuel Curis , Elodie Bouaziz-Amar , Jean-Louis Laplanche Journal of Neuroimmunology, 2019, 334, pp.576993. ⟨10.1016/j.jneuroim.2019.576993⟩ Journal articles hal-02335130v1
	Selecting reference genes in RT-qPCR based on equivalence tests: a network based approach Emmanuel Curis , Calypso Nepost , Diane Grillault Laroche , Cindie Courtin , Jean-Louis Laplanche Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-52217-2⟩ Journal articles hal-02355149v1
	A tutorial on conducting genome-wide association studies: Quality control and statistical analysis Andries Marees , Hilde de Kluiver , Sven Stringer , Florence Vorspan , Emmanuel Curis International Journal of Methods in Psychiatric Research, 2018, 27 (2), ⟨10.1002/mpr.1608⟩ Journal articles hal-01904753v1
	DNA Methylation as a Biomarker of Treatment Response Variability in Serious Mental Illnesses: A Systematic Review Focused on Bipolar Disorder, Schizophrenia, and Major Depressive Disorder Charanraj Goud Alladi , Bruno Etain , Frank Bellivier , Cynthia Marie-Claire International Journal of Molecular Sciences, 2018, 19 (10), ⟨10.3390/ijms19103026⟩ Journal articles hal-01904730v1
	QT length during methadone maintenance treatment: Gene x dose interaction El-Hadi Zerdazi , Florence Vorspan , Andries Marees , François Naccache , Jean-Pierre Lépine Fundamental & Clinical Pharmacology, 2018, 33 (1), pp.96-106. ⟨10.1111/fcp.12405⟩ Journal articles hal-01904739v1
	Determination of sets of covariating gene expression using graph analysis on pairwise expression ratios Emmanuel Curis , Cindie Courtin , Pierre Alexis Geoffroy , Jean-Louis Laplanche , Bruno Saubaméa Bioinformatics, 2018, 35, pp.258 - 265. ⟨10.1093/bioinformatics/bty629⟩ Journal articles hal-03033388v1
	Dopamine ( DRD2 ) and Serotonin ( HTR2A, 2C) Receptor Gene Polymorphisms do not influence early response to Risperidone in South Indian Patients with Schizophrenia Charanraj Goud Alladi , Ravi Philip Rajkumar , Surendiran Adithan , Cynthia Marie-Claire , Frank Bellivier Fundamental & Clinical Pharmacology, In press, ⟨10.1111/fcp.12424⟩ Journal articles hal-01904725v1
	Determination of sets of covariating gene expression using graph analysis on pairwise expression ratios Emmanuel Curis , Cindie Courtin , Pierre Alexis Geoffroy , Jean-Louis Laplanche , Bruno Saubamea Bioinformatics, 2018, ⟨10.1093/bioinformatics/bty629⟩ Journal articles hal-01904746v1
	Lithium effects on serine-threonine kinases activity: High throughput kinomic profiling of lymphoblastoid cell lines from excellent-responders and non-responders bipolar patients Jeverson Moreira , Gaëlle Noé , Savithri Rangarajan , Cindie Courtin , Bruno Etain World Journal of Biological Psychiatry, 2018, pp.1 - 8. ⟨10.1080/15622975.2018.1487078⟩ Journal articles hal-01904750v1
	Dopamine ( DRD 2 ) and Serotonin ( HTR 2A, 2C) Receptor Gene Polymorphisms do not influence early response to Risperidone in South Indian Patients with Schizophrenia Charanraj Goud Alladi , Ravi Philip Rajkumar , Surendiran Adithan , Cynthia Marie-Claire , Frank Bellivier Fundamental & Clinical Pharmacology, 2018, 33, pp.355 - 364. ⟨10.1111/fcp.12424⟩ Journal articles hal-03032951v1
	Molecular Signatures of Lithium Treatment: Current Knowledge Frank Bellivier , Cynthia Marie-Claire Pharmacopsychiatry, 2018, 51 (05), pp.212 - 219. ⟨10.1055/a-0650-4820⟩ Journal articles hal-01904742v1
	Lithium response in bipolar disorders and core clock genes expression Pierre Alexis Geoffroy , Emmanuel Curis , Cindie Courtin , Jeverson Moreira , Thomas Morvillers World Journal of Biological Psychiatry, 2017, pp.1 - 14. ⟨10.1080/15622975.2017.1282174⟩ Journal articles hal-01904765v1
	Pharmacoepigenomics of opiates and methadone maintenance treatment: current data and perspectives Cynthia Marie-Claire , Clément Jourdaine , Jean-Pierre Lépine , Frank Bellivier , Vanessa Bloch Pharmacogenomics, 2017, 18 (14), pp.1359 - 1372. ⟨10.2217/pgs-2017-0040⟩ Journal articles hal-01904755v1
	Lithium response in bipolar disorder: No difference in GADL1 gene expression between cell lines from excellent-responders and non-responders Cynthia Marie-Claire , Jeverson Moreira , Cindie Courtin , Pierre Alexis Geoffroy , Emmanuel Curis Psychiatry Research, 2017, 251, pp.217 - 220. ⟨10.1016/j.psychres.2017.02.022⟩ Journal articles hal-01904761v1
	Variability of response to methadone: genome-wide DNA methylation analysis in two independent cohorts Cynthia Marie-Claire , Severine Crettol , Nicolas Cagnard , Vanessa Bloch , Stéphane Mouly Epigenomics, 2016, 8 (2), pp.181 - 195. ⟨10.2217/epi.15.110⟩ Journal articles hal-01904769v1
	Circadian genes and lithium response in bipolar disorders: associations with PPARGC1A (PGC-1 α ) and RORA P. A. Geoffroy , B. Etain , M. Lajnef , E. H. Zerdazi , C. Brichant-Petitjean Genes, Brain and Behavior, 2016, 15 (7), pp.660 - 668. ⟨10.1111/gbb.12306⟩ Journal articles hal-01904767v1
	Impact of P-glycoprotein at the blood-brain barrier on the uptake of heroin and its main metabolites: behavioral effects and consequences on the transcriptional responses and reinforcing properties Maria Seleman , Hélène Chapy , Salvatore Cisternino , Cindie Courtin , Maria Smirnova Psychopharmacology, 2014, 231 (16), pp.3139 - 3149. ⟨10.1007/s00213-014-3490-9⟩ Journal articles hal-01904771v1
	Comparison of the transcriptional responses induced by acute morphine, methadone and buprenorphine Emilie Belkaï , Dominique Crété , Cindie Courtin , Florence Noble , Cynthia Marie-Claire European Journal of Pharmacology, 2013, 711 (1-3), pp.10-18. ⟨10.1016/j.ejphar.2013.04.015⟩ Journal articles hal-01904772v1
	Transport of Biogenic Amine Neurotransmitters at the Mouse Blood–Retina and Blood–Brain Barriers by Uptake1 and Uptake2 Pascal André , Bruno Saubamea , Véronique Cochois-Guégan , Cynthia Marie-Claire , Julie Cattelotte Journal of Cerebral Blood Flow and Metabolism, 2012, 32 (11), pp.1989 - 2001. ⟨10.1038/jcbfm.2012.109⟩ Journal articles hal-01904808v1
	Chronic and intermittent morphine treatment differently regulates opioid and dopamine systems: a role in locomotor sensitization Cynthia Marie-Claire , Thierry Le Marec , Cynthia Marie , Florence Noble , Nicolas Marie Psychopharmacology, 2011, 216 (2), pp.297 - 303. ⟨10.1007/s00213-011-2223-6⟩ Journal articles hal-01905192v1
	Modulation of MDMA-induced behavioral and transcriptional effects by the delta opioid antagonist naltrindole in mice. Emilie Belkaï , Jean-Michel Scherrmann , Florence Noble , Cynthia Marie-Claire Addiction Biology, 2009, 14 (3), pp.245-52. ⟨10.1111/j.1369-1600.2009.00156.x⟩ Journal articles inserm-00416565v1
	Effects of chronic morphine and morphine withdrawal on gene expression in rat peripheral blood mononuclear cells. Stephane Desjardins , Emilie Belkai , Dominique Crete , Laurie Cordonnier , Jean-Michel Scherrmann Neuropharmacology, 2008, 55 (8), pp.1347-54. ⟨10.1016/j.neuropharm.2008.08.027⟩ Journal articles inserm-00343477v1
	Effects of the selective neurotensin antagonist SR 142948A on 3,4-methylenedioxymethamphetamine-induced behaviours in mice. Cynthia Marie-Claire , Stefano Palminteri , Patrizia Romualdi , Florence Noble Neuropharmacology, 2008, 54 (7), pp.1107-11. ⟨10.1016/j.neuropharm.2008.03.001⟩ Journal articles inserm-00278426v1
	Involvement of D1 dopamine receptor in MDMA-induced locomotor activity and striatal gene expression in mice. Nadia Benturquia , Cindie Courtin , Florence Noble , Cynthia Marie-Claire Brain Research, 2008, 1211, pp.1-5. ⟨10.1016/j.brainres.2008.03.016⟩ Journal articles inserm-00279098v1
	Effects of chronic morphine and morphine withdrawal on gene expression in rat peripheral blood mononuclear cells Stephane Desjardins , Emilie Belkai , Dominique Crete , Laurie Cordonnier , Jean-Michel Scherrmann Neuropharmacology, 2008, 55 (8), pp.1347 - 1354. ⟨10.1016/j.neuropharm.2008.08.027⟩ Journal articles hal-01905201v1
	Rnd family genes are differentially regulated by 3,4-methylenedioxymethamphetamine and cocaine acute treatment in mice brain. Cynthia Marie-Claire , Julie Salzmann , Alexandre David , Cindie Courtin , Corinne Canestrelli Brain Research, 2007, 1134 (1), pp.12-7. ⟨10.1016/j.brainres.2006.11.065⟩ Journal articles inserm-00193078v1
	Expression of drug transporters at the blood-brain barrier using an optimized isolated rat brain microvessel strategy. Salah Yousif , Cynthia Marie-Claire , Françoise Roux , Jean-Michel Scherrmann , Xavier Declèves Brain Research, 2007, 1134 (1), pp.1-11. ⟨10.1016/j.brainres.2006.11.089⟩ Journal articles inserm-00176175v1
	Sensitization to the conditioned rewarding effects of morphine modulates gene expression in rat hippocampus. Cynthia Marie-Claire , Cindie Courtin , Amelie Robert , Xavier Gidrol , Bernard P. Roques Neuropharmacology, 2007, 52 (2), pp.430-5. ⟨10.1016/j.neuropharm.2006.08.012⟩ Journal articles inserm-00162324v1
	Analysis of transcriptional responses in the mouse dorsal striatum following acute 3,4-methylenedioxymethamphetamine (ecstasy): identification of extracellular signal-regulated kinase-controlled genes. Julie Salzmann , Corinne Canestrelli , Florence Noble , Cynthia Marie-Claire Neuroscience, 2006, 137 (2), pp.473-82. ⟨10.1016/j.neuroscience.2005.09.019⟩ Journal articles inserm-00171007v1
	Regulation of genes involved in dopamine transporter modulation by acute cocaine in rat striatum. Cindie Courtin , Dominique Crete , Corinne Canestrelli , Florence Noble , Cynthia Marie-Claire Neuroscience Letters, 2006, 398 (3), pp.235-40. ⟨10.1016/j.neulet.2006.01.001⟩ Journal articles inserm-00162388v1
	Cytoskeletal genes regulation by chronic morphine treatment in rat striatum. Cynthia Marie-Claire , Cindie Courtin , Bernard P. Roques , Florence Noble Neuropsychopharmacology, 2004, 29 (12), pp.2208-15. ⟨10.1038/sj.npp.1300513⟩ Journal articles inserm-00144800v1
	[Acute and long-term effects of ecstasy] Julie Salzmann , Cynthia Marie-Claire , Florence Noble La Presse Médicale, 2004, 33 (18 Suppl), pp.24-32 Journal articles inserm-00176174v1
	Further evidence that the CCK2 receptor is coupled to two transduction pathways using site-directed mutagenesis. Blandine Pommier , Cynthia Marie-Claire , Sophie da Nascimento , Hung-Li Wang , Bernard P. Roques Journal of Neurochemistry, 2003, 85 (2), pp.454-61 Journal articles inserm-00171259v1
	General function of N-terminal propeptide on assisting protein folding and inhibiting catalytic activity based on observations with a chimeric thermolysin-like protease. Bing Tang , Satoru Nirasawa , Motomitsu Kitaoka , Cynthia Marie-Claire , Kiyoshi Hayashi Biochemical and Biophysical Research Communications, 2003, 301 (4), pp.1093-8 Journal articles inserm-00144798v1
	Importance of ERK activation in behavioral and biochemical effects induced by MDMA in mice. Julie Salzmann , Cynthia Marie-Claire , Stephanie Le Guen , Bernard P Roques , Florence Noble British Journal of Pharmacology, 2003, 140 (5), pp.831-8. ⟨10.1038/sj.bjp.0705506⟩ Journal articles inserm-00171261v1
	Fos but not Cart (cocaine and amphetamine regulated transcript) is overexpressed by several drugs of abuse: a comparative study using real-time quantitative polymerase chain reaction in rat brain. Cynthia Marie-Claire , Ingrid Laurendeau , Corine Canestrelli , Cindie Courtin , Michel Vidaud Neuroscience Letters, 2003, 345 (2), pp.77-80 Journal articles inserm-00171266v1
	Folding pathway mediated by an intramolecular chaperone: the structural and functional characterization of the aqualysin I propeptide. Cynthia Marie-Claire , Yukihiro Yabuta , Kyoko Suefuji , Hiroshi Matsuzawa , Ujwal Shinde Journal of Molecular Biology, 2001, 305 (1), pp.151-65. ⟨10.1006/jmbi.2000.4233⟩ Journal articles inserm-00171014v1
	Exploration of the S'1 subsite of neprilysin: a joined molecular modeling and site-directed mutagenesis study. Cynthia Marie-Claire , Gilles Tiraboschi , Emmanuel Ruffet , Nicolas Inguimbert , Marie-Claude Fournie-Zaluski Proteins - Structure, Function and Bioinformatics, 2000, 39 (4), pp.365-71 Journal articles inserm-00171018v1
	The prosequence of thermolysin acts as an intramolecular chaperone when expressed in trans with the mature sequence in Escherichia coli. Cynthia Marie-Claire , Emmanuel Ruffet , Ann Beaumont , Bernard P. Roques Journal of Molecular Biology, 1999, 285 (5), pp.1911-5. ⟨10.1006/jmbi.1998.2449⟩ Journal articles inserm-00171255v1
	Characterization of Glu350 as a critical residue involved in the N-terminal amine binding site of aminopeptidase N (EC 3.4.11.2): insights into its mechanism of action. Nathalie Luciani , Cynthia Marie-Claire , Emmanuel Ruffet , Ann Beaumont , Bernard P. Roques Biochemistry, 1998, 37 (2), pp.686-92. ⟨10.1021/bi971705p⟩ Journal articles inserm-00145193v1
	Intramolecular processing of prothermolysin. Cynthia Marie-Claire , Bernard P. Roques , Ann Beaumont Journal of Biological Chemistry, 1998, 273 (10), pp.5697-701 Journal articles inserm-00145189v1
	Differences in transition state stabilization between thermolysin (EC 3.4.24.27) and neprilysin (EC 3.4.24.11). Cynthia Marie-Claire , Emmanuel Ruffet , Gilles Tiraboschi , Marie-Claude Fournie-Zaluski FEBS Letters, 1998, 438 (3), pp.215-9 Journal articles inserm-00145191v1
	Evidence by site-directed mutagenesis that arginine 203 of thermolysin and arginine 717 of neprilysin (neutral endopeptidase) play equivalent critical roles in substrate hydrolysis and inhibitor binding. Cynthia Marie-Claire , Emmanuel Ruffet , Serge Antonczak , Ann Beaumont , Michael O'Donohue Biochemistry, 1997, 36 (45), pp.13938-45. ⟨10.1021/bi9712495⟩ Journal articles inserm-00171023v1

Cynthia Marie-Claire

Publications

Decreased telomere length in a subgroup of young individuals with bipolar disorders: replication in the FACE-BD cohort and association with the shelterin component POT1

Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study

Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder

Risperidone response in patients with schizophrenia drives DNA methylation changes in immune and neuronal systems

Accelerated aging in bipolar disorders: An exploratory study of six epigenetic clocks

Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder

Associations between circadian misalignment and telomere length in BD: an actigraphy study

Methylomic Biomarkers of Lithium Response in Bipolar Disorder: A Proof of Transferability Study

Telomere length and mitochondrial DNA copy number in bipolar disorder: a sibling study.

Plasma tau, NfL, GFAP and UCHL1 as candidate biomarkers of alcohol withdrawal-associated brain damage: A pilot study

The molecular pathophysiology of mood disorders: From the analysis of single molecular layers to multi-omic integration

Telomere length and mitochondrial DNA copy number in bipolar disorder: identification of a subgroup of young individuals with accelerated cellular aging

Biomarkers of Relapse in Cocaine Use Disorder: A Narrative Review

Individual differences in cocaine-induced conditioned place preference in male rats: Behavioral and transcriptomic evidence

Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder

Mini review: Recent advances on epigenetic effects of lithium

Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients

Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: A critical multi‐disciplinary literature review and agenda for future research from the ISBD task force on chronobiology

Network of co-expressed circadian genes, childhood maltreatment and sleep quality in bipolar disorders

Biomarkers to predict staging and treatment response in opioid dependence: A narrative review

A Comparison of Different Approaches to Clinical Phenotyping of Lithium Response: A Proof of Principle Study Employing Genetic Variants of Three Candidate Circadian Genes

Clinical Trials of Cannabidiol for Substance Use Disorders: Outcome Measures, Surrogate Endpoints, and Biomarkers

Clustering suicidal phenotypes and genetic associations with brain-derived neurotrophic factor in patients with substance use disorders

Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: A critical multi‐disciplinary literature review and agenda for future research from the ISBD task force on chronobiology

A DNA methylation signature discriminates between excellent and non-response to lithium in patients with bipolar disorder type 1

Childhood maltreatment and HPA axis gene expression in bipolar disorders: A gene network analysis.

Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances.

Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances

Selecting reference genes in RT-qPCR based on equivalence tests: a network based approach

QT length during methadone maintenance treatment: gene × dose interaction

Increased plasma levels of high mobility group box 1 protein in patients with bipolar disorder: A pilot study

Selecting reference genes in RT-qPCR based on equivalence tests: a network based approach

A tutorial on conducting genome-wide association studies: Quality control and statistical analysis

DNA Methylation as a Biomarker of Treatment Response Variability in Serious Mental Illnesses: A Systematic Review Focused on Bipolar Disorder, Schizophrenia, and Major Depressive Disorder

QT length during methadone maintenance treatment: Gene x dose interaction

Determination of sets of covariating gene expression using graph analysis on pairwise expression ratios

Dopamine ( DRD2 ) and Serotonin ( HTR2A, 2C) Receptor Gene Polymorphisms do not influence early response to Risperidone in South Indian Patients with Schizophrenia

Determination of sets of covariating gene expression using graph analysis on pairwise expression ratios

Lithium effects on serine-threonine kinases activity: High throughput kinomic profiling of lymphoblastoid cell lines from excellent-responders and non-responders bipolar patients

Dopamine ( DRD 2 ) and Serotonin ( HTR 2A, 2C) Receptor Gene Polymorphisms do not influence early response to Risperidone in South Indian Patients with Schizophrenia

Molecular Signatures of Lithium Treatment: Current Knowledge

Lithium response in bipolar disorders and core clock genes expression

Pharmacoepigenomics of opiates and methadone maintenance treatment: current data and perspectives

Lithium response in bipolar disorder: No difference in GADL1 gene expression between cell lines from excellent-responders and non-responders

Variability of response to methadone: genome-wide DNA methylation analysis in two independent cohorts

Circadian genes and lithium response in bipolar disorders: associations with PPARGC1A (PGC-1 α ) and RORA

Impact of P-glycoprotein at the blood-brain barrier on the uptake of heroin and its main metabolites: behavioral effects and consequences on the transcriptional responses and reinforcing properties

Comparison of the transcriptional responses induced by acute morphine, methadone and buprenorphine

Transport of Biogenic Amine Neurotransmitters at the Mouse Blood–Retina and Blood–Brain Barriers by Uptake1 and Uptake2

Chronic and intermittent morphine treatment differently regulates opioid and dopamine systems: a role in locomotor sensitization

Modulation of MDMA-induced behavioral and transcriptional effects by the delta opioid antagonist naltrindole in mice.

Effects of chronic morphine and morphine withdrawal on gene expression in rat peripheral blood mononuclear cells.

Effects of the selective neurotensin antagonist SR 142948A on 3,4-methylenedioxymethamphetamine-induced behaviours in mice.

Involvement of D1 dopamine receptor in MDMA-induced locomotor activity and striatal gene expression in mice.

Effects of chronic morphine and morphine withdrawal on gene expression in rat peripheral blood mononuclear cells

Rnd family genes are differentially regulated by 3,4-methylenedioxymethamphetamine and cocaine acute treatment in mice brain.

Expression of drug transporters at the blood-brain barrier using an optimized isolated rat brain microvessel strategy.

Sensitization to the conditioned rewarding effects of morphine modulates gene expression in rat hippocampus.

Analysis of transcriptional responses in the mouse dorsal striatum following acute 3,4-methylenedioxymethamphetamine (ecstasy): identification of extracellular signal-regulated kinase-controlled genes.

Regulation of genes involved in dopamine transporter modulation by acute cocaine in rat striatum.

Cytoskeletal genes regulation by chronic morphine treatment in rat striatum.

[Acute and long-term effects of ecstasy]

Further evidence that the CCK2 receptor is coupled to two transduction pathways using site-directed mutagenesis.

General function of N-terminal propeptide on assisting protein folding and inhibiting catalytic activity based on observations with a chimeric thermolysin-like protease.

Importance of ERK activation in behavioral and biochemical effects induced by MDMA in mice.

Fos but not Cart (cocaine and amphetamine regulated transcript) is overexpressed by several drugs of abuse: a comparative study using real-time quantitative polymerase chain reaction in rat brain.

Folding pathway mediated by an intramolecular chaperone: the structural and functional characterization of the aqualysin I propeptide.

Exploration of the S'1 subsite of neprilysin: a joined molecular modeling and site-directed mutagenesis study.

The prosequence of thermolysin acts as an intramolecular chaperone when expressed in trans with the mature sequence in Escherichia coli.

Characterization of Glu350 as a critical residue involved in the N-terminal amine binding site of aminopeptidase N (EC 3.4.11.2): insights into its mechanism of action.

Intramolecular processing of prothermolysin.

Differences in transition state stabilization between thermolysin (EC 3.4.24.27) and neprilysin (EC 3.4.24.11).

Evidence by site-directed mutagenesis that arginine 203 of thermolysin and arginine 717 of neprilysin (neutral endopeptidase) play equivalent critical roles in substrate hydrolysis and inhibitor binding.